Biochemistry and Molecular Biology

Projects 1977 2020

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Finished
Research project
Endogenous Retroviruses
Globins
Genes
Transgenic Mice
Erythroid Cells
Tumor Microenvironment
Neoplasms
Inflammation
Carcinogenesis
Colonic Neoplasms
Retinal Neurons
Diabetic Retinopathy
Retina
Ketone Bodies
Ependymoglial Cells

NCMHD Southeastern Exploratory Sickle Cell Center of Excellence

Adamkiewicz, T., Gibson, R. W., Ikuta, T., Kutlar, A., Gibson, R. W., Gibson, R. W. & Tuan Lo, D.

National Institutes of Health

5/28/0912/31/15

Project: Research project

Sickle Cell Anemia
Hydroxyurea
gamma-Globins
Globins
Opioid Analgesics
B-Cell Chronic Lymphocytic Leukemia
Epigenomics
Methylation
DNA Methylation
High-Throughput Nucleotide Sequencing
Chemokine CXCL12
Neoplasms
Vascular Endothelial Growth Factor Receptor
Therapeutics
Tumor Burden
CDC2 Protein Kinase
Centrosome
Cell Cycle
Cell Death
DNA Damage
Ecdysone
Steroids
Genome
Hormones
Genes
Eukaryotic Initiation Factor-4E
Eukaryotic Initiation Factors
Neoplasms
High-Throughput Screening Assays
Preclinical Drug Evaluations
Plasminogen Activators
Urokinase-Type Plasminogen Activator
Carcinoma
RNA Stability
p38 Mitogen-Activated Protein Kinases

Gamma-globin gene silencing in human red cells

Tuan Lo, D.

National Institutes of Health

9/1/035/31/08

Project: Research project

gamma-Globins
Gene Silencing
Erythroid Precursor Cells
Transcription Factors
beta-Globins

REGULATION OF HUMAN B-GLOBIN GENE IN ERYTHROID CELLS

Tuan Lo, D.

National Institutes of Health

7/1/882/28/97

Project: Research project

Erythroid Cells
Globins
beta-Globins
Genes
epsilon-Globins
Tumor Biomarkers
Semiconductor quantum dots
Color
Gels
Antibodies
Genistein
Prostatic Neoplasms
Neoplasm Metastasis
Isoflavones
Incidence

COLD SPRING HARBOR LABORATORY CANCER RESEARCH CENTER

Ruley, E., Garrels, J., Broker, T., Roberts, R., Greider, C., Tansey, W. P., Lowe, S., Hannon, G., Lazebnik, Y., Kobayashi, R., Krainer, A., Egeblad, M., Spector, D., Powers, S., Grodzicker, T., Marshak, D., Mathews, M., Stenlund, A., Krainer, A., Herr, W., Stillman, B. & Slaughter, C. A.

National Institutes of Health

1/1/7712/31/16

Project: Research project

Proteins
Research
Carcinogenesis
DNA Tumor Viruses
Neoplasms
Cytotoxic T-Lymphocytes
Dendritic Cells
Vaccines
Neoplasm Antigens
Neoplasms
Human Mammary Glands
Breast
Breast Neoplasms
Butyrates
Pyruvic Acid
CpG Islands
DNA Methylation
Genome
Human Genome
Epigenomics

Mentoring Translational Researchers in Louisiana

Esquenazi, S., Rodriguez, P. C., Schieffelin, J., Velasco, C., Davila, E., Estrada, J., Ochoa, A., Rudner, X., Koochekpour, S., Rodriguez, P. C., Zabaleta, J., Arnold, Z., Foster, T. C., Gilbert, J., Schurr, J., Aviles, D., Chou, C., Volaufova, J., Magee, J., Pasternak, R., Liang, M., Rojas, P., Lamotte, L., Yoon, S., Davis, H., Thompson, H., Cui, Y. & Sakamuro, D.

National Institutes of Health

9/30/056/30/15

Project: Research project

Mentors
Dendritic Cells
Research Personnel
Inflammation
Neoplasms
NF-kappa B
Apoptosis
Colon
Carcinoma
Autoimmune Lymphoproliferative Syndrome
gemcitabine
Pancreatic Neoplasms
Methylation
Apoptosis
Regulator Genes

CANCER CENTER SUPPORT GRANT (COMPREHENSIVE)

Maihle, N. J., Lingle, W., O'Connell, M., Diasio, R. B., Greipp, P., David, C., Held, K., Weiland, L., Moertel, C., Burnham, N., Kovach, J., Wold, L., Katzmann, J., Wieand, H., Jenkins, R., Ames, M., Cunningham, J., Wettstein, P. J., Raghavakaimal, S., Buckner, J., Adjei, A., Kocher, J., Highsmith, W. E., Beebe, T., Vile, R., Okuno, S., Federspiel, M., Sarkaria, J., Pitot, H., Salisbury, J., van Deursen, J., Alberts, S., Sargent, D., Roche, P., Thibodeau, S. N., Ingle, J. N., Reid, J., Colon-Otero, G., Galanis, E., Weinshilboum, R., Ames, M., Dewald, G., Liebson, P., Banks, P., Prendergast, F., Wiebeu, E., Clapham, D., Spelsburg, T., Grendahl, D., McCormick, D., Leibson, P., O'Fallon, J., Kline, B., Prendergast, F., Chute, C., McKean, D., Highsmith, E., Kwon, E. D., Wieben, E., Flotte, T., Pitot, H., Leibson, P., Lawson, M., Grendahl, D., McCormick, D. & Jenkins, R. B.

National Institutes of Health

3/1/802/28/19

Project: Research project

Intercellular Signaling Peptides and Proteins
Research
Neoplasms
Radiobiology
Immunogenetics
DNA Damage
Phosphotransferases
Cell Cycle
Proteins
Cell Cycle Checkpoints

TISSUE SPECIFIC ONCOGENESIS MEDIATED BY C-ERBB

Maihle, N. J.

National Institutes of Health

12/1/8911/30/95

Project: Research project

Carcinogenesis
Phosphotransferases
erbB Genes
Genetic Techniques
Primary Cell Culture

IL-6 &SIL-6R GROWTH INHIBITION OF BREAST CARCINOMA

Maihle, N. J.

National Institutes of Health

7/1/964/30/00

Project: Research project

Interleukin-6
Breast Neoplasms
Epithelial Cells
Growth
Breast
Plasminogen Activators
Urokinase-Type Plasminogen Activator
Protein Kinases
Cell Movement
Endothelial Cells

ERV-9 IN THE BETA-GLOBIN LOCUS CONTROL REGION

Tuan Lo, D.

National Institutes of Health

8/1/997/31/04

Project: Research project

Locus Control Region
Endogenous Retroviruses
beta-Globins
Genes
Transcription Factors
Castration
Dietary Supplements
Prostatic Neoplasms
Therapeutics
Punicaceae
Cisplatin
DNA Repair
Neoplasms
E2F1 Transcription Factor
Proto-Oncogene Proteins c-myc
Phosphodiesterase 5 Inhibitors
Chemoprevention
Colonic Neoplasms
Colon
Epithelium
Retina
Diabetic Retinopathy
Inflammation
Anti-Inflammatory Agents
Microglia
B-Cell Chronic Lymphocytic Leukemia
Epigenomics
T-Lymphocytes
Biomarkers
Neoplasms
Molecular Epidemiology
Epigenomics
Methylation
Biomarkers
DNA Methylation
Epigenomics
Non-Hodgkin's Lymphoma
DNA Methylation
Methylation
Transcription Factors
Vitamins
Placenta
Biotin
Ascorbic Acid
Choriocarcinoma
Glioma
Necrosis
Radiation
Capillary Permeability
Central Nervous System Neoplasms
Glioma
Stem Cells
Bone Marrow Cells
Angiogenesis Inducing Agents
Neoplasms
Transplantation Tolerance
Isoantigens
T-Lymphocyte Subsets
Regulatory T-Lymphocytes
T-Lymphocytes
Butyrates
Niacin
Ulcerative Colitis
Dietary Fiber
Inflammation
DNA Damage
Neoplasms
Carcinogenesis
Histone Acetyltransferases
Genetically Modified Animals
Glioma
Genetic Therapy
Stem Cells
Neoplasms
Magnetic Resonance Imaging

TRUNCATED C-ERBB RECEPTORS IN WOMEN WITH OVARIAN CANCER

Maihle, N. J.

National Institutes of Health

8/1/925/31/00

Project: Research project

Proto-Oncogenes
Ovarian Neoplasms
Serum
Neoplasms
Breast Neoplasms
Radiation Injuries
Glioma
Magnetic Resonance Imaging
Cytotoxic T-Lymphocytes
Necrosis
Neoplastic Stem Cells
Colorectal Neoplasms
Fluorouracil
DNA Methylation
Pharmaceutical Preparations

LIGAND INDEPENDENT ONCOGENIC SIGNALING BY ERBB1

Maihle, N. J.

National Institutes of Health

8/5/995/31/05

Project: Research project

Ligands
Tyrosine
Fibroblasts
Calmodulin-Binding Proteins
Guanine Nucleotide Exchange Factors