Biochemistry and Molecular Biology

Research output

Research output per year 1967 2021

• 1311 Article
• 95 Review article
• 23 Chapter
• 17 Comment/debate
• 44 More
  • 14 Letter
  • 11 Editorial
  • 10 Conference contribution
  • 7 Short survey
  • 2 Conference article

Research output per year

Research output per year

Search results

• 2021

  MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment

  Mudd, T. W., Lu, C., Klement, J. D. & Liu, K., Feb 2021, In: Cellular Immunology. 360, 104260.

  Research output: Contribution to journal › Article › peer-review

  • Tumor Microenvironment
  • Colorectal Neoplasms
  • Nivolumab
  • T-Lymphocytes
  • T-Lymphocyte Subsets

• Selenomethionine (Se-Met) induces the cystine/glutamate exchanger SLC7A11 in cultured human retinal pigment epithelial (RPE) cells: Implications for antioxidant therapy in aging retina

  Ananth, S., Miyauchi, S., Thangaraju, M., Jadeja, R. N., Bartoli, M., Ganapathy, V. & Martin, P. M., Jan 2021, In: Antioxidants. 10, 1, p. 1-17 17 p., 9.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epithelial Cells
  • Selenomethionine
  • Cystine
  • Retinal Pigments
  • Glutamic Acid
• 2020

  A Genome-Wide Pooled shRNA Screen Identifies PPP2R2A as a Predictive Biomarker for the Response to ATR and CHK1 Inhibitors

  Qiu, Z., Fa, P., Liu, T., Prasad, C. B., Ma, S., Hong, Z., Chan, E. R., Wang, H., Li, Z., He, K., Wang, Q. E., Williams, T. M., Yan, C., Sizemore, S. T., Narla, G. & Zhang, J., Aug 15 2020, In: Cancer Research. 80, 16, p. 3305-3318 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Small Interfering RNA
  • Genome
  • Non-Small Cell Lung Carcinoma
  • Biomarkers
  • Proto-Oncogene Proteins c-myc

• A Novel Splice Variant of HYAL-4 Drives Malignant Transformation and Predicts Outcome in Patients with Bladder Cancer

  Lokeshwar, V. B., Morera, D. S., Hasanali, S. L., Yates, T. J., Hupe, M. C., Knapp, J., Lokeshwar, S. D., Wang, J., Hennig, M. J. P., Baskar, R., Escudero, D. O., Racine, R. R., Dhir, N., Jordan, A. R., Hoye, K., Azih, I., Manoharan, M., Klaassen, Z., Kavuri, S., Lopez, L. E. & 2 others, Ghosh, S. & Lokeshwar, B. L., Jul 1 2020, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 26, 13, p. 3455-3467 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Urinary Bladder Neoplasms
  • Chondroitinases and Chondroitin Lyases
  • Chondroitin Sulfate Proteoglycans
  • Phenotype
  • Neoplasms

• ATF3 promotes erastin-induced ferroptosis by suppressing system Xc^–

  Wang, L., Liu, Y., Du, T., Yang, H., Lei, L., Guo, M., Ding, H., Zhang, J., Wang, H., Chen, X. & Yan, C., Feb 1 2020, In: Cell Death and Differentiation. 27, 2, p. 662-675 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • erastin
  • Activating Transcription Factor 3
  • Antiporters
  • Lipid Peroxidation
  • Glutathione
  21 Scopus citations

• Autocrine IL6-Mediated Activation of the STAT3-DNMT Axis Silences the TNFα-RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells

  Smith, A. D., Lu, C., Payne, D., Paschall, A. V., Klement, J. D., Redd, P. S., Ibrahim, M. L., Yang, D., Han, Q., Liu, Z., Shi, H., Hartney, T. J., Nayak-Kapoor, A. & Liu, K., Aug 1 2020, In: Cancer Research. 80, 15, p. 3145-3156 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Myeloid-Derived Suppressor Cells
  • Interleukin-6
  • Survival
  • Tumor Microenvironment
  • DNA Methylation
  2 Scopus citations

• C. sakazakii activates AIM2 pathway accompanying with excessive ER stress response in mammalian mammary gland epithelium

  Song, W., Sheng, L., Chen, F., Tian, Y., Li, L., Wang, G., Li, H. & Cai, Y., Mar 1 2020, In: Cell Stress and Chaperones. 25, 2, p. 223-233 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cronobacter sakazakii
  • Inflammasomes
  • Endoplasmic Reticulum Stress
  • Human Mammary Glands
  • Mastitis
  1 Scopus citations

• Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function

  Upadhyay, K. K., Jadeja, R. N., Vyas, H. S., Pandya, B., Joshi, A., Vohra, A., Thounaojam, M. C., Martin, P. M., Bartoli, M. & Devkar, R. V., Jan 2020, In: Redox Biology. 28, 101314.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oxidative stress
  • Non-alcoholic Fatty Liver Disease
  • Carbon Monoxide
  • Molecules
  • Chemical activation
  11 Scopus citations

• CD73 on cancer-associated fibroblasts enhanced by the A_2B-mediated feedforward circuit enforces an immune checkpoint

  Yu, M., Guo, G., Huang, L., Deng, L., Chang, C. S., Achyut, B. R., Canning, M., Xu, N., Arbab, A. S., Bollag, R. J., Rodriguez, P. C., Mellor, A. L., Shi, H., Munn, D. H. & Cui, Y., Dec 1 2020, In: Nature communications. 11, 1, 515.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fibroblasts
  • Cancer-Associated Fibroblasts
  • fibroblasts
  • Tumors
  • cancer
  15 Scopus citations

• Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer

  Bhutia, Y. D., Ogura, J., Grippo, P. J., Torres, C., Sato, T., Wachtel, M., Ramachandran, S., Babu, E., Sivaprakasam, S., Rajasekaran, D., Schniers, B., On, N., Smoot, L., Thangaraju, M., Gnana-Prakasam, J. P. & Ganapathy, V., Mar 2020, In: Asian Journal of Pharmaceutical Sciences. 15, 2, p. 237-251 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epithelial-Mesenchymal Transition
  • Pancreatic Neoplasms
  • Iron
  • Neoplasms
  • p53 Genes
  4 Scopus citations

• Clinical Parameters Outperform Molecular Subtypes for Predicting Outcome in Bladder Cancer: Results from Multiple Cohorts, Including TCGA

  Morera, D. S., Hasanali, S. L., Belew, D., Ghosh, S., Klaassen, Z., Jordan, A. R., Wang, J., Terris, M. K., Bollag, R. J., Merseburger, A. S., Stenzl, A., Soloway, M. S. & Lokeshwar, V. B., Jan 1 2020, In: The Journal of urology. 203, 1, p. 62-72 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Atlases
  • Urinary Bladder Neoplasms
  • Genome
  • Datasets
  • Survival
  11 Scopus citations

• Competitive ubiquitination activates the tumor suppressor p53

  Li, X., Guo, M., Cai, L., Du, T., Liu, Y., Ding, H. F., Wang, H., Zhang, J., Chen, X. & Yan, C., Jun 1 2020, In: Cell Death and Differentiation. 27, 6, p. 1807-1818 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitination
  • Ubiquitin
  • Activating Transcription Factor 3
  • Neoplasms
  • Ubiquitin-Protein Ligases
  3 Scopus citations

• Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome

  Chong, Y., Liu, Y., Lu, S., Cai, B., Qin, H., Chang, C. S., Ren, M., Cowell, J. K. & Hu, T., Apr 15 2020, In: International Journal of Cancer. 146, 8, p. 2243-2254 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Lymphoma
  • Leukemia
  • Phosphotransferases
  • Stem Cells
  • SHP099

• Data on the role of miR-144 in regulating fetal hemoglobin production in retinal pigmented epithelial cells

  Jadeja, R. N. & Martin, P. M., Feb 2020, In: Data in Brief. 28, 104874.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fetal Hemoglobin
  • Epithelial Cells
  • Erythroid Cells
  • Oxidative Stress
  • erythroid Kruppel-like factor
  1 Scopus citations

• Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo

  Elashiry, M., Elashiry, M. M., Elsayed, R., Rajendran, M., Auersvald, C., Zeitoun, R., Rashid, M. H., Ara, R., Meghil, M. M., Liu, Y., Arbab, A. S., Arce, R. M., Hamrick, M., Elsalanty, M., Brendan, M., Pacholczyk, R. & Cutler, C. W., Jan 1 2020, In: Journal of Extracellular Vesicles. 9, 1, 1795362.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes
  • Bone Diseases
  • Dendritic Cells
  • Interleukin-10
  • Alveolar Bone Loss
  1 Scopus citations

• Diagnostic utility of axial imaging in the evaluation of hematuria: A systematic review and critical appraisal of the literature

  Wallis, C. J. D., Sayyid, R. K., Manyevitch, R., Perlis, N., Lokeshwar, V. B., Fleshner, N. E., Terris, M. K., Nielsen, M. E. & Klaassen, Z. W. A., Jul 2020, In: Canadian Urological Association Journal. 15, 2

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hematuria
  • Systematic Reviews
  • Diagnostic Imaging
  • Meta-Analysis
  • Urologic Neoplasms

• Downregulation of PUMA underlies resistance to FGFR1 inhibitors in the stem cell leukemia/lymphoma syndrome

  Liu, Y., Cai, B., Chong, Y., Zhang, H., Kemp, C. A., Lu, S., Chang, C. S., Ren, M., Cowell, J. K. & Hu, T., Oct 1 2020, In: Cell Death and Disease. 11, 10, 884.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lymphoma
  • Leukemia
  • Stem Cells
  • Down-Regulation
  • Apoptosis

• Expression profiles and function of IL6 in polymorphonuclear myeloid-derived suppressor cells

  Ibrahim, M. L., Lu, C., Klement, J. D., Redd, P. S., Yang, D., Smith, A. D. & Liu, K., Nov 1 2020, In: Cancer Immunology, Immunotherapy. 69, 11, p. 2233-2245 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Myeloid-Derived Suppressor Cells
  • Interleukin-6
  • Colon
  • Neoplasms
  • Carcinoma
  1 Scopus citations

• Ferroptosis: An emerging therapeutic opportunity for cancer

  Wang, L., Chen, X. & Yan, C., 2020, (Accepted/In press) In: Genes and Diseases.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • phospholipid-hydroperoxide glutathione peroxidase
  • Cell death
  • Lipid Peroxidation
  • Lipids
  • Cells

• First draft genome for the sand-hopper Trinorchestia longiramus

  Patra, A. K., Chung, O., Yoo, J. Y., Kim, M. S., Yoon, M. G., Choi, J. H. & Yang, Y., Dec 1 2020, In: Scientific Data. 7, 1, 85.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hoppers
  • Gene
  • Draft
  • Genome
  • Genes
  2 Scopus citations

• Homocysteine induces inflammation in retina and brain

  Elsherbiny, N. M., Sharma, I., Kira, D., Alhusban, S., Samra, Y. A., Jadeja, R., Martin, P., Al-Shabrawey, M. & Tawfik, A., Mar 2020, In: Biomolecules. 10, 3, 393.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Homocysteine
  • Retina
  • Brain
  • Macular Degeneration
  • Diabetic Retinopathy
  7 Scopus citations

• Identifying Sialylation Linkages at the Glycopeptide Level by Glycosyltransferase Labeling Assisted Mass Spectrometry (GLAMS)

  Zhu, H., Wang, S., Liu, D., Ding, L., Chen, C., Liu, Y., Wu, Z., Bollag, R., Liu, K., Alexander, W. M., Yin, J., Ma, C., Li, L. & Wang, P. G., May 5 2020, In: Analytical Chemistry. 92, 9, p. 6297-6303 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Isomers
  • Glycosyltransferases
  • Mass spectrometry
  • Glycopeptides
  • Sialoglycoproteins
  1 Scopus citations

• Implications of NAD⁺ Metabolism in the Aging Retina and Retinal Degeneration

  Jadeja, R. N., Thounaojam, M. C., Bartoli, M. & Martin, P. M., 2020, In: Oxidative medicine and cellular longevity. 2020, 2692794.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Metabolism
  • Retinal Degeneration
  • NAD
  • Retina
  • Aging of materials
  3 Scopus citations

• Inactivation of endothelial ADAM17 reduces retinal ischemia-reperfusion induced neuronal and vascular damage

  Gutsaeva, D. R., Shalaby, L., Powell, F. L., Thounaojam, M. C., Abouhish, H., Wetzstein, S. A., Jadeja, R. N., Kwok, H. F., Martin, P. M. & Bartoli, M., Aug 1 2020, In: International journal of molecular sciences. 21, 15, p. 1-18 18 p., 5379.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ischemia
  • ADAM17 Protein
  • deactivation
  • mice
  • Metalloproteases

• Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration

  Jadeja, R. N., Jones, M. A., Abdelrahman, A. A., Powell, F. L., Thounaojam, M. C., Gutsaeva, D., Bartoli, M. & Martin, P. M., Jan 2020, In: Redox Biology. 28, 101336.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oxidative stress
  • Retinal Degeneration
  • Retinal Pigments
  • Retinal Pigment Epithelium
  • MicroRNAs
  12 Scopus citations

• Inhibition of HDAC6 attenuates diabetes-induced retinal redox imbalance and microangiopathy

  Abouhish, H., Thounaojam, M., Jadeja, R. N., Gutsaeva, D. R., Powell, F. L., Khriza, M., Martin, P. M. & Bartoli, M., Jul 2020, In: Antioxidants. 9, 7, p. 1-19 19 p., 599.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Histone Deacetylase 6
  • Oxidation-Reduction
  • Medical problems
  • tubastatin A
  • Rats
  2 Scopus citations

• Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

  Yang, W., Yu, T., Huang, X., Bilotta, A. J., Xu, L., Lu, Y., Sun, J., Pan, F., Zhou, J., Zhang, W., Yao, S., Maynard, C. L., Singh, N., Dann, S. M., Liu, Z. & Cong, Y., Dec 1 2020, In: Nature communications. 11, 1, 4457.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • interleukin-22
  • fatty acids
  • Volatile Fatty Acids
  • immunity
  • Gastrointestinal Microbiome
  7 Scopus citations

• Invasion of Human Retinal Pigment Epithelial Cells by Porphyromonas gingivalis leading to Vacuolar/Cytosolic localization and Autophagy dysfunction In-Vitro

  Arjunan, P., Swaminathan, R., Yuan, J., Al-Shabrawey, M., Espinosa-Heidmann, D. G., Nussbaum, J., Martin, P. M. & Cutler, C. W., Dec 1 2020, In: Scientific reports. 10, 1, 7468.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Porphyromonas gingivalis
  • Retinal Pigments
  • Autophagy
  • Epithelial Cells
  • In Vitro Techniques
  2 Scopus citations

• Investigation of the effect of dietary intake of omega-3 polyunsaturated fatty acids on trauma-induced white matter injury with quantitative diffusion MRI in mice

  Reyes, L. D., Haight, T., Desai, A., Chen, H., Bosomtwi, A., Korotcov, A., Dardzinski, B., Kim, H. Y. & Pierpaoli, C., Nov 1 2020, In: Journal of Neuroscience Research. 98, 11, p. 2232-2244 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Diffusion Magnetic Resonance Imaging
  • Anisotropy
  • Omega-3 Fatty Acids
  • Unsaturated Fatty Acids
  • White Matter

• Label-free ferrohydrodynamic cell separation of circulating tumor cells

  Zhao, W., Cheng, R., Jenkins, B. D., Davis, M. B., Kavuri, S. K., Hao, Z., Schroeder, C. & Mao, L., 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 868-869 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Tumors
  • Cells
  • Labels
  • Blood
  • Biomarkers

• LncRNA CDKN2B-AS1/miR-141/cyclin D network regulates tumor progression and metastasis of renal cell carcinoma

  Dasgupta, P., Kulkarni, P., Majid, S., Hashimoto, Y., Shiina, M., Shahryari, V., Bhat, N. S., Tabatabai, L., Yamamura, S., Saini, S., Tanaka, Y. & Dahiya, R., Aug 1 2020, In: Cell Death and Disease. 11, 8, 660.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cyclin D
  • Renal Cell Carcinoma
  • Neoplasm Metastasis
  • Cyclins
  • Neoplasms

• Mechanistic dissection of diabetic retinopathy using the protein-metabolite interactome

  Patrick, A. T., He, W., Madu, J., Sripathi, S. R., Choi, S., Lee, K., Samson, F. P., Powell, F. L., Bartoli, M., Jee, D., Gutsaeva, D. R. & Jahng, W. J., 2020, (Accepted/In press) In: Journal of Diabetes and Metabolic Disorders.

  Research output: Contribution to journal › Article › peer-review

  • Diabetic Retinopathy
  • Dissection
  • Metabolome
  • prohibitin
  • Biomarkers
  1 Scopus citations

• MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer

  Bhagirath, D., Yang, T. L., Akoto, T., Patel, N., Tabatabai, L. Z. & Saini, S., Dec 22 2020, In: Oncotarget. 11, 51, p. 4681-4692 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epithelial-Mesenchymal Transition
  • MicroRNAs
  • Prostatic Neoplasms
  • Neoplasms
  • Monosomy 8p Chromosome 8

• MicroRNA determinants of neuroendocrine differentiation in metastatic castration-resistant prostate cancer

  Bhagirath, D., Liston, M., Patel, N., Akoto, T., Lui, B., Yang, T. L., To, D. M., Majid, S., Dahiya, R., Tabatabai, Z. L. & Saini, S., Dec 3 2020, In: Oncogene. 39, 49, p. 7209-7223 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Castration
  • MicroRNAs
  • Prostatic Neoplasms
  • Nodal Protein
  • abiraterone
  1 Scopus citations

• Molecular Bio-Imaging Probe for Non-Invasive Differentiation Between Human Leiomyoma Versus Leiomyosarcoma

  Shalaby, S., Khater, M., Laknaur, A., Arbab, A. & Al-Hendy, A., Feb 1 2020, In: Reproductive Sciences. 27, 2, p. 644-654 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Leiomyosarcoma
  • Molecular Imaging
  • Leiomyoma
  • Sarcoma
  • Survivin
  1 Scopus citations

• Molecular signaling pathways and therapeutic targets in hepatocellular carcinoma

  Dimri, M. & Satyanarayana, A., Feb 2020, In: Cancers. 12, 2, 491.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hepatocellular Carcinoma
  • Catenins
  • Critical Pathways
  • Wnt Signaling Pathway
  • TOR Serine-Threonine Kinases
  21 Scopus citations

• Molecular targeting of renal cell carcinoma by an oral combination

  Jordan, A. R., Wang, J., Yates, T. J., Hasanali, S. L., Lokeshwar, S. D., Morera, D. S., Shamaladevi, N., Li, C. S., Klaassen, Z., Terris, M. K., Thangaraju, M., Singh, A. B., Soloway, M. S. & Lokeshwar, V. B., May 1 2020, In: Oncogenesis. 9, 5, 52.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sorafenib
  • Renal Cell Carcinoma
  • Hymecromone
  • Down-Regulation
  • UDP-glucuronosyltransferase 1A9

• Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury

  Vaibhav, K., Braun, M., Alverson, K., Khodadadi, H., Kutiyanawalla, A., Ward, A., Banerjee, C., Sparks, T., Malik, A., Rashid, M. H., Rashid, M. H., Khan, M. B., Waters, M. F., Hess, D. C., Arbab, A. S., Vender, J. R., Hoda, N., Hoda, N., Hoda, N., Baban, B. & 3 others, Baban, B., Baban, B. & Dhandapani, K. M., May 2020, In: Science Advances. 6, 22, EAAX8847.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Traps
  • Traumatic Brain Injury
  • Deoxyribonuclease I
  • dornase alfa
  • Protein-Arginine Deiminases
  4 Scopus citations

• Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide

  Horimatsu, T., Blomkalns, A. L., Ogbi, M., Moses, M., Kim, D., Patel, S., Gilreath, N., Reid, L., Benson, T. W., Pye, J., Ahmadieh, S., Thompson, A., Robbins, N., Mann, A., Edgell, A., Benjamin, S., Stansfield, B. K., Huo, Y., Fulton, D. J., Agarwal, G. & 4 others, Singh, N., Offermanns, S., Weintraub, N. L. & Kim, H. W., Dec 1 2020, In: Cardiovascular Research. 116, 14, p. 2226-2238 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Niacinamide
  • Niacin
  • Abdominal Aortic Aneurysm
  • NAD
  • Adventitia
  5 Scopus citations

• Novel small-molecule LG1836 inhibits the in vivo growth of castration-resistant prostate cancer

  Chen, Y., Li, X., Mamouni, K., Yang, Y., Danaher, A., White, J., Liu, H. Y., Kucuk, O., Gera, L. & Wu, D., Sep 1 2020, In: Prostate. 80, 12, p. 993-1005 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Castration
  • Prostatic Neoplasms
  • Growth
  • Androgen Receptors
  • Androgens

• NRF2 mediates γ-globin gene regulation through epigenetic modifications in a β-YAC transgenic mouse model

  Zhu, X., Xi, C., Ward, A., Takezaki, M., Shi, H., Peterson, K. R. & Pace, B. S., Sep 1 2020, In: Experimental Biology and Medicine. 245, 15, p. 1308-1318 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Globins
  • Gene expression
  • Transgenic Mice
  • Epigenomics
  • Genes

• Oncoprotein GT198 vaccination delays tumor growth in MMTV-PyMT mice

  Achyut, B. R., Zhang, H., Angara, K., Mivechi, N. F., Arbab, A. S. & Ko, L., Apr 28 2020, In: Cancer Letters. 476, p. 57-66 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncogene Proteins
  • Vaccination
  • Growth
  • Neoplasms
  • Breast Neoplasms

• Osteopontin: A key regulator of tumor progression and immunomodulation

  Moorman, H. R., Poschel, D., Klement, J. D., Lu, C., Redd, P. S. & Liu, K., Nov 2020, In: Cancers. 12, 11, p. 1-31 31 p., 3379.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Osteopontin
  • Immunomodulation
  • Neoplasms
  • T-Lymphocytes
  • Tumor Microenvironment

• P50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy

  Lu, C., Klement, J. D., Smith, A. D., Yang, D., Waller, J. L., Browning, D. D., Munn, D. H. & Liu, K., Oct 13 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, 230.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tumor Escape
  • Cytotoxic T-Lymphocytes
  • Immunotherapy
  • T-Lymphocytes
  • Nivolumab
  1 Scopus citations

• Pancreatic Adenocarcinoma: Unconventional Approaches for an Unconventional Disease

  Gromisch, C., Qadan, M., Machado, M. A., Liu, K., Colson, Y. & Grinstaff, M. W., Aug 15 2020, In: Cancer Research. 80, 16, p. 3179-3192 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Adenocarcinoma
  • Pancreatic Neoplasms
  • Drug Development
  • Nanomedicine
  • Nanotechnology
  1 Scopus citations

• PCC0208017, a novel small-molecule inhibitor of MARK3/MARK4, suppresses glioma progression in vitro and in vivo

  Li, F., Liu, Z., Sun, H., Li, C., Wang, W., Ye, L., Yan, C., Tian, J. & Wang, H., Feb 2020, In: Acta Pharmaceutica Sinica B. 10, 2, p. 289-300 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glioma
  • In Vitro Techniques
  • Microtubules
  • Phosphotransferases
  • M Phase Cell Cycle Checkpoints
  8 Scopus citations

• Persistent STAT5 activation reprograms the epigenetic landscape in CD4⁺ T cells to drive polyfunctionality and antitumor immunity

  Ding, Z. C., Shi, H., Aboelella, N. S., Fesenkova, K., Park, E. J., Liu, Z., Pei, L., Li, J., McIndoe, R. A., Xu, H., Piazza, G. A., Blazar, B. R., Munn, D. H. & Zhou, G., Oct 30 2020, In: Science immunology. 5, 52, aba5962.

  Research output: Contribution to journal › Article › peer-review

  • STAT5 Transcription Factor
  • Transcriptional Activation
  • Epigenomics
  • Immunity
  • T-Lymphocytes
  1 Scopus citations

• Poly-IC enhances the effectiveness of cancer immunotherapy by promoting T cell tumor infiltration

  Sultan, H., Wu, J., Fesenkova, V. I., Fan, A. E., Addis, D., Salazar, A. M. & Celis, E., Sep 21 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, e001224.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Immunotherapy
  • T-Lymphocytes
  • Carboxymethylcellulose Sodium
  • Lysine
  • Neoplasms
  2 Scopus citations

• Promotion of epithelial hyperplasia by interleukin-8—CXCR axis in human prostate

  Smith, D. K., Hasanali, S. L., Wang, J., Kallifatidis, G., Morera, D. S., Jordan, A. R., Terris, M. K., Klaassen, Z., Bollag, R., Lokeshwar, V. B. & Lokeshwar, B. L., Sep 1 2020, In: Prostate. 80, 12, p. 938-949 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukins
  • Prostatic Hyperplasia
  • Hyperplasia
  • Prostate
  • Interleukin-8
  1 Scopus citations

• Rac1/2 activation promotes FGFR1 driven leukemogenesis in stem cell leukemia/lymphoma syndrome

  Hu, T., Chong, Y., Lu, S., McGuinness, M., Williams, D. A. & Cowell, J. K., Jan 31 2020, In: Haematologica. 105, 2, p. E68-E71

  Research output: Contribution to journal › Letter › peer-review

  Open Access