Biochemistry and Molecular Biology

Research Output 1968 2019

2019

African Clinicians' Prioritization of Needs in International Breast Cancer Partnerships

Gyan, K., Kyei, I., Susick, L. L., Chen, Y., Davis, M. B., Salem, B. & Newman, L. A., Feb 1 2019, In : JAMA Surgery. 154, 2, p. 184-185 2 p.

Research output: Contribution to journal › Letter

Breast Neoplasms

Alcohol-induced ketonemia is associated with lowering of blood glucose, downregulation of gluconeogenic genes, and depletion of hepatic glycogen in type 2 diabetic db/db mice

Srinivasan, M. P., Shawky, N. M., Kaphalia, B. S., Thangaraju, M. & Segar, L., Feb 1 2019, In : Biochemical Pharmacology. 160, p. 46-61 16 p.

Research output: Contribution to journal › Article

Liver Glycogen
Ketosis
Blood Glucose
Ethanol
Down-Regulation

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc–

Wang, L., Liu, Y., Du, T., Yang, H., Lei, L., Guo, M., Ding, H., Zhang, J., Wang, H., Chen, X. & Yan, C., Jan 1 2019, In : Cell Death and Differentiation.

Research output: Contribution to journal › Article

Open Access
Activating Transcription Factor 3
Antiporters
Lipid Peroxidation
Glutathione
Cell Death
1 Citation (Scopus)

Atypical chemokine receptor 1 (DARC/ACKR1) in breast tumors is associated with survival, circulating chemokines, tumor-infiltrating immune cells, and African ancestry

Jenkins, B. D., Martini, R. N., Hire, R., Brown, A., Bennett, B., Brown, I., Howerth, E. W., Egan, M., Hodgson, J., Yates, C., Kittles, R., Chitale, D., Ali, H., Nathanson, D., Nikolinakos, P., Newman, L., Monteil, M. A. & Davis, M. B., Apr 1 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 4, p. 690-700 11 p.

Research output: Contribution to journal › Article

Open Access
Chemokine Receptors
Chemokines
Breast Neoplasms
Neoplasms
Alleles

B-arrestins regulate stem cell-like phenotype and response to chemotherapy in bladder cancer

Kallifatidis, G., Smith, D. K., Morera, D. S., Gao, J., Hennig, M. J., Hoy, J. J., Pearce, R. F., Dabke, I. R., Li, J., Merseburger, A. S., Kuczyk, M. A., Lokeshwar, V. B. & Lokeshwar, B. L., Apr 1 2019, In : Molecular cancer therapeutics. 18, 4, p. 801-811 11 p.

Research output: Contribution to journal › Article

Arrestins
gemcitabine
Urinary Bladder Neoplasms
Stem Cells
Phenotype

Chaperone-mediated autophagy degradation of IGF-1Rβ induced by NVP-AUY922 in pancreatic cancer

Xue, N., Lai, F., Du, T., Ji, M., Liu, D., Yan, C., Zhang, S., Yu, X., Jin, J. & Chen, X., Sep 1 2019, In : Cellular and Molecular Life Sciences. 76, 17, p. 3433-3447 15 p.

Research output: Contribution to journal › Article

Autophagy
Pancreatic Neoplasms
HSP90 Heat-Shock Proteins
Proteasome Endopeptidase Complex
Lysosomes

Computational methods for detection of differentially methylated regions using kernel distance and scan statistics

Dunbar, F., Xu, H., Ryu, D., Ghosh, S., Shi, H. & George, V., Apr 1 2019, In : Genes. 10, 4, 298.

Research output: Contribution to journal › Article

Open Access
DNA Methylation
B-Cell Chronic Lymphocytic Leukemia
Genomics
Epigenomics
Research Personnel

Correction: The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20 (Oncogene, (2019), 38, 4, (469-482), 10.1038/s41388-018-0472-0)

Lee, E., Ouzounova, M., Piranlioglu, R., Ma, M. T., Guzel, M., Marasco, D., Chadli, A., Gestwicki, J. E., Cowell, J. K., Wicha, M. S., Hassan, K. A. & Korkaya, H., Jul 11 2019, In : Oncogene. 38, 28, 1 p.

Research output: Contribution to journal › Comment/debate

Open Access
Financial Management
Oncogenes
Breast Neoplasms
Laboratory Animals
Genomics

Correction to: Giant Magnetic Heat Induction of Magnesium-Doped γ-Fe 2 O 3 Superparamagnetic Nanoparticles for Completely Killing Tumors (Advanced Materials, (2018), 30, 6, (1704362), 10.1002/adma.201704362)

Jang, J. T., Lee, J., Seon, J., Ju, E., Kim, M., Kim, Y. I., Kim, M. G., Takemura, Y., Arbab, A. S., Kang, K. W., Park, K. H., Paek, S. H. & Bae, S., Mar 22 2019, In : Advanced Materials. 31, 12, 1806347.

Research output: Contribution to journal › Comment/debate

Magnesium
Tumors
Nanoparticles
Fourier transforms
Infrared radiation

Corrigendum to “CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma” (Neoplasia (2018) 20(10) (1070–1082), (S1476558618303798) (10.1016/j.neo.2018.08.011))

Angara, K., Borin, T. F., Rashid, M. H., Lebedyeva, I. O., Ara, R., Lin, P-C., Iskander, A. S. M., Bollag, R. J., Achyut, B. R. & Arbab, A. S., Jan 1 2019, In : Neoplasia (United States). 21, 1, p. 156-157 2 p.

Research output: Contribution to journal › Comment/debate

Glioblastoma
Blood Vessels
Phenotype
Manuscripts
Neoplasms

Cryptotanshinone inhibits esophageal squamous-cell carcinoma in vitro and in vivo through the suppression of STAT3 activation

Ji, Y., Liu, Y., Xue, N., Du, T., Wang, L., Huang, R., Li, L., Yan, C. & Chen, X., Jan 1 2019, In : OncoTargets and Therapy. 12, p. 883-896 14 p.

Research output: Contribution to journal › Article

Open Access
Esophageal Neoplasms
Interleukin-6
Janus Kinase 2
Apoptosis
Salvia miltiorrhiza

CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells

Chen, L., Tang, S., Zhang, F. F., Garcia, V., Falck, J. R., Schwartzman, M. L., Arbab, A. S. & Guo, A. M., Jun 1 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 6, p. H1468-H1479

Research output: Contribution to journal › Article

Cytochrome P-450 CYP4A
Ischemia
Endothelial Cells
Chemokine CXCL12
Pharmacology
1 Citation (Scopus)

Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study

Khodaverdian, V., Tapadar, S., MacDonald, I. A., Xu, Y., Ho, P. Y., Bridges, A., Rajpurohit, P., Sanghani, B. A., Fan, Y., Thangaraju, M., Hathaway, N. A. & Oyelere, A. K., Dec 1 2019, In : Scientific Reports. 9, 1, 4802.

Research output: Contribution to journal › Article

Open Access
Histone Demethylases
Structure-Activity Relationship
Iron
Catalytic Domain
deferiprone

Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock

Subramani, K., Chu, X., Warren, M., Lee, M., Lu, S., Singh, N. & Raju, R. P., Mar 1 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 3, p. 688-695 8 p.

Research output: Contribution to journal › Article

Hemorrhagic Shock
Niacin
NAD
Sirtuin 1
Nicotinamide Mononucleotide

Dietary myo-inositol chemoprevents lung carcinogenesis via boosting immune system in Kras mouse model

Piranlioglu, R., Korkaya, H. & Hassan, K. A., Jan 1 2019, In : Journal of Thoracic Disease. 11, 3, p. 632-635 4 p.

Research output: Contribution to journal › Review article

Inositol
Immune System
Carcinogenesis
Lung
3 Citations (Scopus)

Discovery, synthesis of novel fusidic acid derivatives possessed amino-terminal groups at the 3-hydroxyl position with anticancer activity

Ni, J., Guo, M., Cao, Y., Lei, L., Liu, K., Wang, B., Lu, F., Zhai, R., Gao, X., Yan, C., Wang, H. & Bi, Y., Jan 15 2019, In : European Journal of Medicinal Chemistry. p. 122-131 10 p.

Research output: Contribution to journal › Article

Fusidic Acid
Hydroxyl Radical
Tumors
Derivatives
Neoplasms

Discovery and Validation of a Novel Neutrophil Activation Marker Associated with Obesity

Pan, Y., Choi, J-H., Shi, H., Zhang, L., Su, S. & Wang, X., Dec 1 2019, In : Scientific Reports. 9, 1, 3433.

Research output: Contribution to journal › Article

Neutrophil Activation
Obesity
Alkaline Phosphatase
Cardiovascular Diseases
Kidney
1 Citation (Scopus)

Heterogeneity of the head and neck squamous cell carcinoma immune landscape and its impact on immunotherapy

Canning, M., Guo, G., Yu, M., Myint, C., Groves, M. W., Byrd, J. K. & Cui, Y., Jan 1 2019, In : Frontiers in Cell and Developmental Biology. 7, APR, 52.

Research output: Contribution to journal › Review article

Open Access
Immunotherapy
Carcinoma, squamous cell of head and neck
Therapeutics
Papillomavirus Infections
Transcriptome

Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation

Yang, L., Zha, Y., Ding, J., Ye, B., Liu, M., Yan, C., Dong, Z., Cui, H. & Ding, H., Jan 1 2019, In : Oncogenesis. 8, 1, 3.

Research output: Contribution to journal › Article

Histone Demethylases
Neuroblastoma
Epigenomics
Cell Differentiation
Histones

HLA-G dimer targets Granzyme B pathway to prolong human renal allograft survival

Ajith, A., Portik-Dobos, V., Nguyen, A. T., Callaway, C., Horuzsko, D. D., Kapoor, R., Zayas Montalvo, C. F., Maenaka, K., Mulloy, L. L. & Horuzsko, A., Apr 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 4, p. 5220-5236 17 p.

Research output: Contribution to journal › Article

Granzymes
HLA Antigens
Dimers
Allografts
Kidney
1 Citation (Scopus)

Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation

Cai, Y., Zhu, G., Liu, S., Pan, Z., Quintero, M., Poole, C. J., Lu, C., Zhu, H., Islam, B., Van Riggelen, J., Browning, D. D., Liu, K., Blumberg, R., Singh, N. & Li, H., Dec 1 2019, In : Cell Discovery. 5, 1, 7.

Research output: Contribution to journal › Article

Ubiquitin-Protein Ligases
Paneth Cells
Ubiquitin
Homeostasis
Inflammation

Intracellular reduction in ATP levels contributes to CYT997-induced suppression of metastasis of head and neck squamous carcinoma

Zhao, X., Lang, L., He, L., Gao, L., Chyan, D., Xiong, Y., Li, H., Peng, H. & Teng, Y., Feb 1 2019, In : Journal of Cellular and Molecular Medicine. 23, 2, p. 1174-1182 9 p.

Research output: Contribution to journal › Article

Squamous Cell Carcinoma
Neck
Adenosine Triphosphate
Head
Neoplasm Metastasis
2 Citations (Scopus)

Loss of fas expression and function is coupled with colon cancer resistance to immune checkpoint inhibitor immunotherapy

Xiao, W., Ibrahim, M. L., Redd, P. S., Klement, J. D., Lu, C., Yang, D., Savage, N. M. & Liu, K., Feb 1 2019, In : Molecular Cancer Research. 17, 2, p. 420-430 11 p.

Research output: Contribution to journal › Article

Immunotherapy
Colonic Neoplasms
Microsatellite Repeats
Neoplastic Stem Cells
Apoptosis

Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis

Jadeja, R. N., Jones, M. A., Fromal, O., Powell, F. L., Khurana, S., Singh, N. & Martin, P. M., Jan 1 2019, In : Aging. 11, 2, p. 386-400 15 p.

Research output: Contribution to journal › Article

Liver
Lipogenesis
Lipids
Gene Expression
Adipose Tissue
1 Citation (Scopus)

Loss of the BCR-FGFR1 GEF domain suppresses RhoA activation and enhances B-lymphomagenesis in mice

Hu, T., Chong, Y., Lu, S., Qin, H., Ren, M., Savage, N. M., Chang, C. S. & Cowell, J. K., Jan 1 2019, In : Cancer Research. 79, 1, p. 114-124 11 p.

Research output: Contribution to journal › Article

Guanidine
Nucleotides
Lymphoma
Leukemia
Stem Cells

Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin

Folk, W. P., Kumari, A., Iwasaki, T., Pyndiah, S., Johnson, J. C., Cassimere, E. K., Abdulovic-Cui, A. L. & Sakamuro, D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 14, p. 5700-5719 20 p.

Research output: Contribution to journal › Article

Ataxia Telangiectasia
Nuclear Proteins
Cisplatin
Tumors
Phosphotransferases

MiR322 mediates cardioprotection against ischemia/reperfusion injury via FBXW7/notch pathway

Chen, Z., Su, X., Shen, Y., Jin, Y., Luo, T., Kim, I., Weintraub, N. L. & Tang, Y. L., Aug 1 2019, In : Journal of molecular and cellular cardiology. 133, p. 67-74 8 p.

Research output: Contribution to journal › Article

Reperfusion Injury
Myocardial Reperfusion
Myocardial Ischemia
Apoptosis
Cardiac Myocytes

Monosodium urate contributes to retinal inflammation and progression of diabetic retinopathy

Thounaojam, M., Montemari, A., Powell, F. L., Malla, P., Gutsaeva, D. R., Bachettoni, A., Ripandelli, G., Repossi, A., Tawfik, A. M., Martin, P. M., Facchiano, F. & Bartoli, M., Jan 1 2019, In : Diabetes. 68, 5, p. 1014-1025 12 p.

Research output: Contribution to journal › Article

Open Access
Diabetic Retinopathy
Uric Acid
Inflammation
Streptozocin
Hyperglycemia

MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL

Poole, C. J., Lodh, A., Choi, J-H. & Van Riggelen, J., Jul 2 2019, In : Epigenetics and Chromatin. 12, 1, 41.

Research output: Contribution to journal › Article

Open Access
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
DNA Methylation
Phenotype
Gene Expression
5-Methylcytosine
1 Citation (Scopus)

Neoblast-enriched zinc finger protein FIR1 triggers local proliferation during planarian regeneration

Han, X. S., Wang, C., Guo, F. H., Huang, S., Qin, Y. W., Zhao, X. X. & Jing, Q., Jan 1 2019, In : Protein and Cell. 10, 1, p. 43-59 17 p.

Research output: Contribution to journal › Article

Planarians
Zinc Fingers
Stem cells
Zinc
Regeneration

Plasticity and potency of mammary stem cell subsets during mammary gland development

Lee, E., Piranlioglu, R., Wicha, M. S. & Korkaya, H., May 1 2019, In : International journal of molecular sciences. 20, 9, 2357.

Research output: Contribution to journal › Article

Open Access
mammary glands
stem cells
Human Mammary Glands
Stem cells
plastic properties

Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model

Piranlioglu, R., Lee, E. M., Ouzounova, M., Bollag, R. J., Vinyard, A., Arbab, A. S., Marasco, D., Guzel, M., Cowell, J. K., Thangaraju, M., Chadli, A., Hassan, K. A., Wicha, M. S., Celis, E. & Korkaya, H., Dec 1 2019, In : Nature Communications. 10, 1, 1430.

Research output: Contribution to journal › Article

immunity
mice
Tumors
Immunity
tumors

Salubrinal, a novel inhibitor of eIF-2α dephosphorylation, promotes erythropoiesis at early stage targeted by ufmylation pathway

Chen, F., Xing, C., Zhang, W., Li, J., Hu, T., Li, L., Li, H. & Cai, Y., Oct 1 2019, In : Journal of Cellular Physiology. 234, 10, p. 18560-18570 11 p.

Research output: Contribution to journal › Article

Erythropoiesis
Anemia
Up-Regulation
Unfolded Protein Response
Erythrocyte Indices

Small molecule BKM1972 inhibits human prostate cancer growth and overcomes docetaxel resistance in intraosseous models

Chen, Y., Gera, L., Zhang, S., Li, X., Yang, Y., Mamouni, K., Wu, A. Y., Liu, H. Y., Kucuk, O. & Wu, D., Apr 1 2019, In : Cancer Letters. 446, p. 62-72 11 p.

Research output: Contribution to journal › Article

docetaxel
Prostatic Neoplasms
Growth
Neoplasm Metastasis
STAT3 Transcription Factor

SuV39H1 represses the expression of cytotoxic T-lymphocyte effector genes to promote colon tumor immune evasion

Lu, C., Yang, D., Klement, J. D., Oh, I. K., Savage, N. M., Waller, J. L., Colby, A. H., Grinstaff, M. W., Oberlies, N. H., Pearce, C. J., Xie, Z., Kulp, S. K., Coss, C. C., Phelps, M. A., Albers, T., Lebedyeva, I. O. & Liu, K., Mar 1 2019, In : Cancer Immunology Research. 7, 3, p. 414-427 14 p.

Research output: Contribution to journal › Article

Tumor Escape
Cytotoxic T-Lymphocytes
Colon
Tumor Microenvironment
Microsatellite Repeats

Systemic antibiotic therapy reduces circulating inflammatory dendritic cells and Treg–Th17 plasticity in periodontitis

Rajendran, M., Looney, S. W., Singh, N., Elashiry, M., Meghil, M. M., El-Awady, A. R., Tawfik, O., Susin, C., Arce Munoz, R. M. & Cutler, C. W., May 1 2019, In : Journal of Immunology. 202, 9, p. 2690-2699 10 p.

Research output: Contribution to journal › Article

Periodontitis
Dendritic Cells
Anti-Bacterial Agents
Porphyromonas gingivalis
Therapeutics

The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis

Eisa, N. H., Jilani, Y., Kainth, K., Redd, P., Lu, S., Bougrine, O., Sater, H. A., Patwardhan, C. A., Shull, A., Shi, H., Liu, K., Elsherbiny, N. M., Eissa, L. A., El-Shishtawy, M. M., Horuzsko, A., Bollag, R. J., Maihle, N. J., Roig, J., Korkaya, H., Cowell, J. K. & 1 others, Chadli, A., Jan 1 2019, In : Journal of Biological Chemistry. 294, 14, p. 5246-5260 15 p.

Research output: Contribution to journal › Article

Myosins
Carcinogenesis
Phosphotransferases
Cell proliferation
Cells
2 Citations (Scopus)

The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20

Lee, E., Ouzounova, M., Piranlioglu, R., Ma, M. T., Guzel, M., Marasco, D., Chadli, A., Gestwicki, J. E., Cowell, J. K., Wicha, M. S., Hassan, K. A. & Korkaya, H., Jan 24 2019, In : Oncogene. 38, 4, p. 469-482 14 p.

Research output: Contribution to journal › Article

Breast Neoplasms
Cell Death
Triple Negative Breast Neoplasms
Heterografts
Cell Line
1 Citation (Scopus)

The route of administration dictates the immunogenicity of peptide-based cancer vaccines in mice

Sultan, H., Kumai, T., Nagato, T., Wu, J., Salazar, A. M. & Celis, E., Mar 13 2019, In : Cancer Immunology, Immunotherapy. 68, 3, p. 455-466 12 p.

Research output: Contribution to journal › Article

Cancer Vaccines
Subunit Vaccines
Cytotoxic T-Lymphocytes
Peptides
Vaccines
1 Citation (Scopus)

THZ1 suppresses human non-small-cell lung cancer cells in vitro through interference with cancer metabolism

Cheng, Z. J., Miao, D. L., Su, Q. Y., Tang, X. L., Wang, X. L., Deng, L. B., Shi, H. & Xin, H. B., Jun 1 2019, In : Acta Pharmacologica Sinica. 40, 6, p. 814-822 9 p.

Research output: Contribution to journal › Article

Non-Small Cell Lung Carcinoma
Neoplasms
Glutaminase
Glutamine
Cell Line
1 Citation (Scopus)

Transient inhibition of neddylation at neonatal stage evokes reversible cardiomyopathy and predisposes the heart to isoproterenol-induced heart failure

Zou, J., Ma, W., Littlejohn, R., Li, J., Stansfield, B. K., Kim, I., Liu, J., Zhou, J., Weintraub, N. L. & Su, H., Jun 1 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 6, p. H1406-H1416

Research output: Contribution to journal › Article

Cardiomyopathies
Isoproterenol
Heart Failure
Cardiomegaly
Ubiquitins

Type i interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes

Lu, C., Klement, J. D., Ibrahim, M. L., Xiao, W., Redd, P. S., Nayak, A., Zhou, G. & Liu, K., Jun 22 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, 157.

Research output: Contribution to journal › Article

Open Access
Granzymes
Cytotoxic T-Lymphocytes
Interferons
Growth
Neoplasms
1 Citation (Scopus)

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR

Zhu, H., Bhatt, B., Sivaprakasam, S., Cai, Y., Liu, S., Kodeboyina, S. K., Patel, N., Savage, N. M., Sharma, A. K., Kaufman, R. J., Li, H. & Singh, N., Dec 1 2019, In : Nature Communications. 10, 1, 1084.

Research output: Contribution to journal › Article

Unfolded Protein Response
Plasma Cells
proteins
Plasmas
expansion
1 Citation (Scopus)

UFL1 promotes histone H4 ufmylation and ATM activation

Qin, B., Yu, J., Nowsheen, S., Wang, M., Tu, X., Liu, T., Li, H., Wang, L. & Lou, Z., Dec 1 2019, In : Nature Communications. 10, 1, 1242.

Research output: Contribution to journal › Article

Open Access
ataxia
Ataxia Telangiectasia
Ligases
Histones
Chemical activation
2018

[125 I]IodoDPA-713 binding to 18 kDa translocator protein (TSPO) in a mouse model of intracerebral hemorrhage: Implications for neuroimaging

Bonsack, F., Foss, C. A., Arbab, A. S., Alleyne, C. H., Pomper, M. G. & Sukumari Ramesh, S., Feb 22 2018, In : Frontiers in Neuroscience. 12, FEB, 66.

Research output: Contribution to journal › Article

Cerebral Hemorrhage
Neuroimaging
Proteins
Brain
Autoradiography
18 Citations (Scopus)

A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes

Bayoumi, A. S., Park, K. M., Wang, Y., Teoh, J. P., Aonuma, T., Tang, Y. L., Su, H., Weintraub, N. L. & Kim, I., Jan 1 2018, In : Journal of molecular and cellular cardiology. 114, p. 72-82 11 p.

Research output: Contribution to journal › Article

MicroRNAs
Cardiac Myocytes
Myocardial Infarction
Adrenergic Receptors
Apoptosis
20 Citations (Scopus)

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R. W., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journal › Article

Antigen-Presenting Cells
Myeloid Cells
Immunotherapy
Cell Differentiation
Cross-Priming

AhR ligand aminoflavone suppresses α6-integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

Campbell, P. S., Mavingire, N., Khan, S., Rowland, L. K., Wooten, J. V., Opoku-Agyeman, A., Guevara, A., Soto, U., Cavalli, F., Loaiza-Pérez, A. I., Nagaraj, G., Denham, L. J., Adeoye, O., Jenkins, B. D., Davis, M. B., Schiff, R. & Brantley, E. J., Jan 1 2018, In : Journal of Cellular Physiology. 234, 1, p. 108-121 14 p.

Research output: Contribution to journal › Article

aminoflavone
Tamoxifen
Cells
Breast Neoplasms
Ligands
3 Citations (Scopus)

Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death

Habtetsion, T., Ding, Z-C., Pi, W., Li, T., Lu, C., Chen, T., Xi, C., Spartz, H., Liu, K., Hao, Z., Mivechi, N. F., Huo, Y., Blazar, B. R., Munn, D. H. & Zhou, G., Aug 7 2018, In : Cell Metabolism. 28, 2, p. 228-242.e6

Research output: Contribution to journal › Article

Oxidative Stress
Cell Death
T-Lymphocytes
Adoptive Immunotherapy
Neoplasms
1 Citation (Scopus)

Androgen receptor and ALDH1 expression among internationally diverse patient populations

Jiagge, E., Jibril, A. S., Davis, M. B., Murga-Zamalloa, C., Kleer, C. G., Gyan, K., Divine, G., Hoenerhoff, M., Bensenhave, J., Awuah, B., Oppong, J., Adjei, E., Salem, B., Toy, K., Merajver, S., Wicha, M. & Newman, L., Mar 1 2018, In : Journal of Global Oncology. 2018, 4

Research output: Contribution to journal › Article

Androgen Receptors
Triple Negative Breast Neoplasms
African Americans
Population
Breast Neoplasms