Biochemistry and Molecular Biology

Research Output 1968 2020

1968
273 Citations (Scopus)

The biology of isolated chromatin

Bonner, J., Dahmus, M. E., Fambrough, D., Huang, R. C. C., Marushige, K. & Tuan, D. Y. H., Jan 1 1968, In : Science. 159, 3810, p. 47-56 10 p.

Research output: Contribution to journalArticle

Chromatin
Chromosomes
Genes
1969
99 Citations (Scopus)

Optical absorbance and optical rotatory dispersion studies on calf thymus nucleohistone

Tuan Lo, D. & Bonner, J., Oct 14 1969, In : Journal of Molecular Biology. 45, 1, p. 59-76 18 p.

Research output: Contribution to journalArticle

Optical Rotatory Dispersion
Histones
Thymus Gland
DNA
Osmolar Concentration
1973
49 Citations (Scopus)

Isolation of the Nonhistone Proteins of Rat Walker Carcinoma 256. Their Association with Tumor Angiogenesis

Tuan, D., Smith, S., Folkman, J. & Merler, E., Aug 1 1973, In : Biochemistry. 12, 17, p. 3159-3165 7 p.

Research output: Contribution to journalArticle

Walker Carcinoma 256
Rats
Tumors
Histones
Guanidine
1975
Open Access
1976

Disruption of Escherichia coli Outer Membranes by EM 49. A New Membrane Active Peptide Antibiotic

Rosenthal, K. S., Storm, D. R. & Swanson, P. E., Dec 1 1976, In : Biochemistry. 15, 26, p. 5783-5792 10 p.

Research output: Contribution to journalArticle

Escherichia coli
Anti-Bacterial Agents
Membranes
Peptides
Phospholipids
1977
40 Citations (Scopus)

Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells

Prasad, P. D., Ramamoorthy, S., Leibach, F. H. & Ganapathy, V., Sep 1 1977, In : Placenta. 18, 7, p. 527-533 7 p.

Research output: Contribution to journalArticle

Choriocarcinoma
Biotin
Vitamins
Sodium
Valinomycin

Disruption of the escherichia coli outer membrane permeability barrier by immobilized polymyxin b

Rosenthal, K. S. & Storm, D. R., Jan 1 1977, In : The Journal of Antibiotics. 30, 12, p. 1087-1092 6 p.

Research output: Contribution to journalArticle

Open Access
Polymyxins
Polymyxin B
Permeability
Escherichia coli
Membranes

Inhibition of Escherichia coli Growth and Respiration by Polymyxin B Covalently Attached to Agarose Beads

LaPorte, D. C., Rosenthal, K. S. & Storm, D. R., Apr 1 1977, In : Biochemistry. 16, 8, p. 1642-1648 7 p.

Research output: Contribution to journalArticle

Polymyxins
Polymyxin B
Sepharose
Escherichia coli
Respiration

Mechanism of action of EM 49, membrane-active peptide antibiotic

Rosenthal, K. S., Ferguson, R. A. & Storm, D. R., Jan 1 1977, In : Antimicrobial agents and chemotherapy. 12, 6, p. 665-672 8 p.

Research output: Contribution to journalArticle

Open Access
Anti-Bacterial Agents
Peptides
Membranes
Respiration
Polymyxin B

Polymyxin and related peptide antibiotics

Storm, D. R., Rosenthal, K. S. & Swanson, P. E., Dec 1 1977, In : Annual Review of Biochemistry. Vol. 46, p. 723-763 41 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Sequence specific interaction of the chromosomal proteins with DNA

Tuan, D., Chetsanga, C. & Doty, P. M., Oct 1 1977, In : Nucleic Acids Research. 4, 10, p. 3415-3439 25 p.

Research output: Contribution to journalArticle

Chromatin
DNA
Nucleic Acid Repetitive Sequences
Proteins
Histones
1979
66 Citations (Scopus)

Restriction endonuclease mapping of the human γ globin gene loci

Tuan, D., Biro, P. A., Deriel, J. K., Lazarus, H. & Forget, B. G., Jun 11 1979, In : Nucleic Acids Research. 6, 7, p. 2519-2544 26 p.

Research output: Contribution to journalArticle

Restriction Mapping
Globins
Genes
DNA
Fetal Hemoglobin
1980

ANALYSIS OF β‐GLOBIN GENES IN β^ THALASSEMIA

Tuan, D., Biro, P. A., De Riel, J. K. & Forget, B. G., May 1980, In : Annals of the New York Academy of Sciences. 344, 1, p. 12-30 19 p.

Research output: Contribution to journalArticle

Genetic Suppression
Nucleic Acid Hybridization
Chromosome Deletion
Thalassemia
Globins
20 Citations (Scopus)

Cotransfer of circular and linear prokaryotic and eukaryotic DNA sequences into mouse cells.

Hsiung, N., Warrick, H., deRiel, J. K., Tuan, D., Forget, B. G., Skoultchi, A. & Kucherlapati, R., Aug 1980, In : Proceedings of the National Academy of Sciences of the United States of America. 77, 8, p. 4852-4856 5 p.

Research output: Contribution to journalArticle

Thymidine Kinase
Plasmids
Genes
beta-Globins
Transfection
42 Citations (Scopus)

Heterogeneity in the molecular basis of hereditary persistence of fetal haemoglobin

Tuan Lo, D., Murnane, M. J., DeRiel, J. K. & Forget, B. G., Dec 1 1980, In : Nature. 285, 5763, p. 335-337 3 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Globins
Gene Deletion
DNA
Hemoglobins
13 Citations (Scopus)

Morphological and ultrastructural features of Nikitinsporites canadensis chaloner, a devonian megaspore from the frasnian of canada

Taylor, T. N., Maihle, N. J. & Hills, L. V., Jan 1 1980, In : Review of Palaeobotany and Palynology. 30, C, p. 89-99 11 p.

Research output: Contribution to journalArticle

megaspores
Frasnian
ornamentation
ultrastructure
appendages
1 Citation (Scopus)

Physicochemical measurement of the base composition of mRNA-related sequences of the human α and β globin genes

Tuan, D. & G. Forget, B., Sep 1 1980, In : Molecular Biology Reports. 6, 3, p. 179-183 5 p.

Research output: Contribution to journalArticle

Globins
Base Composition
Complementary DNA
Messenger RNA
Genes
20 Citations (Scopus)

POSSIBLE FUNCTIONS OF CALMODULIN IN PROTOZOA

Satir, B. H., Garofalo, R. S., Gilligan, D. M. & Maihle, N. J., Dec 1980, In : Annals of the New York Academy of Sciences. 356, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Protozoa
Trifluoperazine
Calcium-Binding Proteins
Calmodulin
Animals
1981
56 Citations (Scopus)

Calmodulin localization during capping and receptor-mediated endocytosis

Salisbury, J. L., Condeelis, J. S., Maihle, N. J. & Satir, P., Dec 1 1981, In : Nature. 294, 5837, p. 163-166 4 p.

Research output: Contribution to journalArticle

Receptor Aggregation
Calmodulin
Endocytosis
Trifluoperazine
Ligands
31 Citations (Scopus)

Presence and indirect immunofluorescent localization of calmodulin in Paramecium tetraurelia

Maihle, N. I., Dedman, J. R., Means, A. R., Chafouleas, J. G. & Satir, B. H., Oct 19 1981, In : Journal of Cell Biology. 89, 3, p. 695-699 5 p.

Research output: Contribution to journalArticle

Paramecium tetraurelia
Organoids
Paramecium
Calcium-Binding Proteins
Cilia
13 Citations (Scopus)

Ultrastructure of the flagellar apparatus of the green alga Tetraselmis subcordiformis - With special consideration given to the function of the rhizoplast and rhizanchora

Salisbury, J. L., Swanson, J. A., Floyd, G. L., Hall, R. & Maihle, N. J., Mar 1 1981, In : Protoplasma. 107, 1-2, p. 1-11 11 p.

Research output: Contribution to journalArticle

Basal Bodies
Tetraselmis
Chlorophyta
microtubules
ultrastructure
1982
64 Citations (Scopus)

A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin

Jagadeeswaran, P., Tuan, D., Forget, B. G. & Weissman, S. M., Dec 1 1982, In : Nature. 296, 5856, p. 469-470 2 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Nucleic Acid Repetitive Sequences
Gene Deletion
Globins
Genes
35 Citations (Scopus)

The cross-reactive idiotype of A-strain mice Serological and structural analyses

Capra, J. D., Slaughter, C. A., Milner, E. C. B., Estess, P. & Tucker, P. W., Jan 1 1982, In : Immunology Today. 3, 12, p. 332-339 8 p.

Research output: Contribution to journalReview article

Hybridomas
Goats
Antibody Formation
Technology
arsonic acid
1983
83 Citations (Scopus)

cDNA cloning of the bovine low density lipoprotein receptor: Feedback regulation of a receptor mRNA

Russell, D. W., Yamamoto, T., Schneider, W. J., Slaughter, C. A., Brown, M. S. & Goldstein, J. L., Jan 1 1983, In : Proceedings of the National Academy of Sciences of the United States of America. 80, 24 I, p. 7501-7505 5 p.

Research output: Contribution to journalArticle

LDL Receptors
Organism Cloning
Complementary DNA
Messenger RNA
Cyanogen Bromide
3 Citations (Scopus)

Molecular studies of mutations that increase Hb F production in man.

Forget, B. G., Tuan Lo, D., Newman, M. V., Feingold, E. A., Collins, F., Fukumaki, Y., Jagadeeswaran, P. & Weissman, S. M., Dec 1 1983, In : Progress in clinical and biological research. 134, p. 65-76 12 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Chromosome Deletion
Thalassemia
Chromosome Mapping
Gene Expression Regulation
20 Citations (Scopus)

Neoisostegane, a new bisbenzocyclooctadiene lignan lactone from Steganotaenia araliacea hochst.

Hicks, R. P. & Sneden, A. T., Jan 1 1983, In : Tetrahedron Letters. 24, 29, p. 2987-2990 4 p.

Research output: Contribution to journalArticle

Araliaceae
Lignans
Lactones
Nuclear magnetic resonance
Proton Magnetic Resonance Spectroscopy
1984
80 Citations (Scopus)
Globins
K562 Cells
Deoxyribonuclease I
Leukemia
myc Genes
15 Citations (Scopus)

Neoisostegane, A New Bisbenzocyclooctadiene Lignan Lactone from Steganotaenia Araliacea1

Taafrout, M., Rouessac, F., Robin, J. P., Hicks, R. P., Shillady, D. D. & Sneden, A. T., May 1984, In : Journal of Natural Products. 47, 4, p. 600-606 7 p.

Research output: Contribution to journalArticle

Lignans
Lactones
Araliaceae
Isomerization
Functional groups
1985
63 Citations (Scopus)

Agonist-induced alteration in the membrane form of muscarinic cholinergic receptors

Harden, T. K., Petch, L. A., Traynelis, S. F. & Waldo, G. L., Dec 1 1985, In : Journal of Biological Chemistry. 260, 24, p. 13060-13066 7 p.

Research output: Contribution to journalArticle

Cholinergic Receptors
Muscarinic Receptors
Cholinergic Agents
Carbachol
Membranes

Agonist-induced change in the membrane form of muscarinic cholinergic receptors (MR) in astrocytoma cells

Harden, T. K., Petch Lee, L. A. & Traynelis, S. F., Jan 1 1985, In : Federation Proceedings. 44, 5

Research output: Contribution to journalArticle

Astrocytoma
Cholinergic Receptors
Muscarinic Receptors
Membranes
7 Citations (Scopus)

Preparation of glucosidic derivatives of steganol

Hicks, R. P. & Sneden, A. T., Jan 1 1985, In : Journal of Natural Products. 48, 3, p. 357-362 6 p.

Research output: Contribution to journalArticle

Glucosides
Derivatives
Podophyllotoxin
Acetaldehyde
Assays
28 Citations (Scopus)

Protein secretion in Tetrahymena thermophila: Characterization of the secretory mutant strain SB281

Maihle, N. J. & Satir, B. H., Jan 1 1985, In : Journal of Cell Science. VOL. 78, p. 49-65 17 p.

Research output: Contribution to journalArticle

Freeze Fracturing
Tetrahymena thermophila
Tetrahymena
Species Specificity
Membrane Fusion
412 Citations (Scopus)

The 'β-like-globin' gene domain in human erythroid cells

Tuan Lo, D., Solomon, W., Li, Q. & London, I. M., Jan 1 1985, In : Proceedings of the National Academy of Sciences of the United States of America. 82, 19, p. 6384-6388 5 p.

Research output: Contribution to journalArticle

Erythroid Cells
Globins
Deoxyribonuclease I
Genes
DNA
1986

2-Deoxy-d-glucose inhibition of herpes simplex virus type-1 receptor expression

Mohanty, J. G. & Rosenthal, K. S., May 1986, In : Antiviral Research. 6, 3, p. 137-149 13 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Glucose
Growth Inhibitors
Vesicular Stomatitis
Wheat Germ Agglutinins
3 Citations (Scopus)

Blood utilization for elective general surgery at the Port-of-Spain General Hospital.

Monteil, M. A. & Naraynsingh, V., Dec 1 1986, In : West Indian Medical Journal. 35, 4, p. 293-294 2 p.

Research output: Contribution to journalArticle

Hospital Surgery Department
Blood Grouping and Crossmatching
Trinidad and Tobago
Blood Banks
Hospital Departments
61 Citations (Scopus)

Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids

Henthorn, P. S., Knoll, B. J., Raducha, M., Rothblum, K. N., Slaughter, C. A., Weiss, M., Lafferty, M. A., Fischer, T. & Harris, H., Dec 19 1986, In : Proceedings of the National Academy of Sciences of the United States of America. 83, 15, p. 5597-5601 5 p.

Research output: Contribution to journalArticle

Amino Acid Sequence
Complementary DNA
Alleles
Amino Acids
Gene Library
1987
56 Citations (Scopus)

Application of a protein-blotting procedure to the study of human glucocorticoid receptor interactions with DNA

Silva, C. M., Tully, D. B., Petch, L. A., Jewell, C. M. & Cidlowski, J. A., Jun 11 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 7, p. 1744-1748 5 p.

Research output: Contribution to journalArticle

Glucocorticoid Receptors
Mouse mammary tumor virus
DNA
Proteins
Collodion
14 Citations (Scopus)

SELECTIVE IMMUNODEFICIENCY AFFECTING STAPHYLOCOCCAL RESPONSE

Monteil, M., Hobbs, J. & Citron, K., Oct 17 1987, In : The Lancet. 330, 8564, p. 880-883 4 p.

Research output: Contribution to journalArticle

Immunoglobulin G
Staphylococcal Infections
Sepsis
Antibodies
Therapeutics
1988

Enhancement of the antiviral and interferon-inducing activities of poly r(A-U) by carminic acid

Jamison, J. M., Flowers, D. G., Jamison, E., Kitareewan, S., Krabill, K., Rosenthal, K. S. & Tsai, C. C., 1988, In : Life sciences. 42, 15, p. 1477-1483 7 p.

Research output: Contribution to journalArticle

Carmine
Poly A-U
Interferons
Antiviral Agents
Ribonucleotides
60 Citations (Scopus)

Epidermal growth factor (EGF) and hormones stimulate phosphoinositide hydrolysis and increase EGF receptor protein synthesis and mRNA levels in rat liver epithelial cells. Evidence for protein kinase C-dependent and -independent pathways

Earp, H. S., Hepler, J. R., Petch, L. A., Miller, A., Berry, A. R., Harris, J. A., Raymond, V. W., McCune, B. K., Lee, L. W., Grisham, J. W. & Harden, T. K., Jan 1 1988, In : Journal of Biological Chemistry. 263, 27, p. 13868-13874 7 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Epidermal Growth Factor Receptor
Epidermal Growth Factor
Liver
Protein Kinase C
135 Citations (Scopus)

Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Gil, G., Smith, J. R., Goldstein, J. L., Slaughter, C. A., Orth, K., Brown, M. S. & Osborn, T. F., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 23, p. 8963-8967 5 p.

Research output: Contribution to journalArticle

NFI Transcription Factors
Oxidoreductases
Genes
Proteins
Cricetinae
24 Citations (Scopus)

Proviral insertional activation of c-erbB: Differential processing of the protein products arising from two alternate transcripts

Maihle, N. J., Raines, M. A., Flickinger, T. W. & Kung, H. J., Jan 1 1988, In : Molecular and Cellular Biology. 8, 11, p. 4868-4876 9 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins
Genetic Transcription
Genetic Transformation
Proviruses
Proto-Oncogenes
23 Citations (Scopus)

Septic scarlet fever due to streptococcus pyogenes cellulitis

Shaunak, S., Wendon, J., Monteil, M. & Gordon, A. M., Nov 1988, In : QJM. 69, 2, p. 921-925 5 p.

Research output: Contribution to journalArticle

Scarlet Fever
Cellulitis
Streptococcus pyogenes
Toxemia
Young Adult
1989
199 Citations (Scopus)

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human 'β-like globin' genes

Tuan, D. Y. H., Solomon, W. B., London, I. M. & Lee, D. P., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 8, p. 2554-2558 5 p.

Research output: Contribution to journalArticle

Globins
Genes
Erythroid Cells
Genetic Complementation Test
30 Citations (Scopus)

C-erbB and the epidermal growth-factor receptor: a molecule with dual identity

Maihle, N. J. & Kung, H. J., Feb 1989, In : BBA - Reviews on Cancer. 948, 3, p. 287-304 18 p.

Research output: Contribution to journalReview article

Proto-Oncogene Proteins
Neoplastic Cell Transformation
Genetic Transcription
Epidermal Growth Factor Receptor
Phosphorylation
16 Citations (Scopus)

Disease tropism of c-erbB: Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation

Pelley, R. J., Maihle, N. J., Boerkoel, C., Shu, H. K., Carter, T. H., Moscovici, C. & Kung, H. J., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 18, p. 7164-7168 5 p.

Research output: Contribution to journalArticle

Tropism
Tyrosine
Phosphotransferases
Avian Leukosis Virus
Leukemia, Erythroblastic, Acute
9 Citations (Scopus)

One hundred years of retinoblastoma Research: From the clinic to the gene and back again

Cowell, J. K., Jun 1 1989, In : Ophthalmic Paediatrics and Genetics. 10, 2, p. 75-88 14 p.

Research output: Contribution to journalArticle

Retinoblastoma
Research
Genes
Neoplasms
Chromosomes, Human, Pair 13
1990
171 Citations (Scopus)

A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue

Petch, L. A., Harris, J., Raymond, V. W., Blasband, A., Lee, D. C. & Earp, H. S., Jan 1 1990, In : Molecular and Cellular Biology. 10, 6, p. 2973-2982 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Messenger RNA
Clone Cells
Epidermal Growth Factor
Hepatocytes
4 Citations (Scopus)

NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays

Kaplita, P. V., Abreu, M. E., Connor, J. R., Erickson, R. H., Ferkany, J. W., Hicks, R. P., Schenden, J. A., Noronha‐Blob, L. & Hanson, R. C., 1990, In : Drug Development Research. 20, 4, p. 429-443 15 p.

Research output: Contribution to journalArticle

Adenosine A1 Receptor Antagonists
Xanthine
Guinea Pigs
Adenylyl Cyclases
Adenosine A2 Receptors

Retroviral insertional mutagenesis: the making of a receptor-oncogene.

Kung, H. J., Pelley, R. J., Shu, H. K., Maihle, N. J., Raines, M., Carter, T., Boerkoel, C., Moscovici, G. & Moscovici, C., Jan 1 1990, In : Developments in biological standardization. 72, p. 139-144 6 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Avian Leukosis Virus
Leukemia, Erythroblastic, Acute
Insertional Mutagenesis
Viral DNA