Biochemistry and Molecular Biology

Research Output

[125 I]IodoDPA-713 binding to 18 kDa translocator protein (TSPO) in a mouse model of intracerebral hemorrhage: Implications for neuroimaging

Bonsack, F., Foss, C. A., Arbab, A. S., Alleyne, C. H., Pomper, M. G. & Sukumari-Ramesh, S., Feb 22 2018, In : Frontiers in Neuroscience. 12, FEB, 66.

Research output: Contribution to journalArticle

2 Scopus citations

[Biological effects of sCD40L on acute myeloid leukemia cells HL-60 and its mechanism].

Li, J., Chen, Q. & Ren, M., Apr 1 2012, In : Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 33, 4, p. 324-326 3 p.

Research output: Contribution to journalArticle

1,3,8-Trisubstituted Xanthines. Effects of Substitution Pattern upon Adenosine Receptor A1/A2 Affinity

Erickson, R. H., Hiner, R. N., Feeney, S. W., Blake, P. R., Rzeszotarski, W. J., Hicks, R. P., Costello, D. G. & Abreu, M. E., Apr 1 1991, In : Journal of Medicinal Chemistry. 34, 4, p. 1431-1435 5 p.

Research output: Contribution to journalArticle

46 Scopus citations

10B7, human epidermal growth factor receptor, extracellular domain peptide 290-311

Maihle, N. J., Jan 1 1997, In : Hybridoma. 16, 3, p. 293-294 2 p.

Research output: Contribution to journalArticle

53BP1 promotes microhomology-mediated end-joining in G1-phase cells

Xiong, X., Du, Z., Wang, Y., Feng, Z., Fan, P., Yan, C., Willers, H. & Zhang, J., 2015, In : Nucleic Acids Research. 43, 3, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation

Wang, J., Peng, L., Zhang, R., Zheng, Z., Chen, C., Cheung, K. L., Cui, M., Bian, G., Xu, F., Chiang, D., Hu, Y., Chen, Y., Lu, G., Yang, J., Zhang, H., Yang, J., Zhu, H., Chen, S. H., Liu, K., Zhou, M. M. & 4 others, Sikora, A. G., Li, L., Jiang, B. & Xiong, H., Apr 12 2016, In : Oncotarget. 7, 15, p. 19312-19326 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

A (GATA)7 motif located in the 5' boundary area of the human β-globin locus control region exhibits silencer activity in erythroid cells

Ramchandran, R., Bengra, C., Whitney, B., Lanclos, K. & Tuan, D., 2000, In : American Journal of Hematology. 65, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

A 1.8 kb alternative transcript from the human epidermal growth factor receptor gene encodes a truncated form of the receptor

Reiter, J. L. & Maihle, N. J., 1996, In : Nucleic Acids Research. 24, 20, p. 4050-4056 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease

Zhou, J., Wu, R., High, A. A., Slaughter, C. A., Finkelstein, D., Rehg, J. E., Redecke, V. & Häcker, H., Nov 1 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 44, p. E998-E1006

Research output: Contribution to journalArticle

67 Scopus citations

A2A adenosine receptor protects tumors from antitumor T cells

Ohta, A., Gorelik, E., Prasad, S. J., Ronchese, F., Lukashev, D., Wong, M. K. K., Huang, X., Caldwell, S., Liu, K., Smith, P., Chen, J. F., Jackson, E. K., Apasov, S., Abrams, S. & Sitkovsky, M., Aug 29 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 35, p. 13132-13137 6 p.

Research output: Contribution to journalArticle

485 Scopus citations

A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37

Wu, E., Fernandez, J., Fleck, S. K., Von Seggern, D. J., Huang, S. & Nemerow, G. R., Jan 20 2001, In : Virology. 279, 1, p. 78-89 12 p.

Research output: Contribution to journalArticle

63 Scopus citations
4 Scopus citations

Aberrant Epigenetic Gene Regulation in Lymphoid Malignancies

Taylor, K. H., Briley, A., Wang, Z., Cheng, J., Shi, H. & Caldwell, C. W., Jan 1 2013, In : Seminars in Hematology. 50, 1, p. 38-47 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

A brief overview of antimicrobial peptides containing unnatural amino acids and Ligand-based approaches for peptide Ligands

Bhonsle, J. B., Clark, T., Bartolotti, L. & Hicks, R. P., Jan 1 2013, In : Current Topics in Medicinal Chemistry. 13, 24, p. 3205-3224 20 p.

Research output: Contribution to journalArticle

20 Scopus citations

Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: Role of cystine/glutamate exchanger

Gnana-Prakasam, J. P., Thangaraju, M., Liu, K., Ha, Y., Martin, P. M., Smith, S. B. & Ganapathy, V., Dec 1 2009, In : Biochemical Journal. 424, 2, p. 243-252 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes

Bayoumi, A. S., Park, K. M., Wang, Y., Teoh, J. P., Aonuma, T., Tang, Y. L., Su, H., Weintraub, N. L. & Kim, I., Jan 2018, In : Journal of molecular and cellular cardiology. 114, p. 72-82 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

A chemokine/chemokine receptor signature potentially predicts clinical outcome in colorectal cancer patients

Mitchell, A., Hasanali, S. L., Morera, D. S., Baskar, R., Wang, X., Khan, R., Talukder, A., Li, C. S., Manoharan, M., Jordan, A. R., Wang, J., Bollag, R. J., Singh, N., Albo, D., Ghosh, S. & Lokeshwar, V. B., 2019, In : Cancer biomarkers : section A of Disease markers. 26, 3, p. 291-301 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

A chromosomal region 7p11.2 transcript map: Its development and application to the study of EGFR amplicons in glioblastoma

Eley, G. D., Reiter, J. L., Pandita, A., Park, S., Jenkins, R. B., Maihle, N. J. & James, C. D., 2002, In : Neuro-Oncology. 4, 2, p. 86-94 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

A cis-regulatory map of the Drosophila genome

Négre, N., Brown, C. D., Ma, L., Bristow, C. A., Miller, S. W., Wagner, U., Kheradpour, P., Eaton, M. L., Loriaux, P., Sealfon, R., Li, Z., Ishii, H., Spokony, R. F., Chen, J., Hwang, L., Cheng, C., Auburn, R. P., Davis, M. B., Domanus, M., Shah, P. K. & 20 others, Morrison, C. A., Zieba, J., Suchy, S., Senderowicz, L., Victorsen, A., Bild, N. A., Grundstad, A. J., Hanley, D., MacAlpine, D. M., Mannervik, M., Venken, K., Bellen, H., White, R., Gerstein, M., Russell, S., Grossman, R. L., Ren, B., Posakony, J. W., Kellis, M. & White, K. P., Mar 24 2011, In : Nature. 471, 7339, p. 527-531 5 p.

Research output: Contribution to journalArticle

336 Scopus citations

A critical role of CXCR2 PDZ-mediated interactions in endothelial progenitor cell homing and angiogenesis

Hou, Y., Wu, Y., Farooq, S. M., Guan, X., Wang, S., Liu, Y., Oblak, J. J., Holcomb, J., Jiang, Y., Strieter, R. M., Lasley, R. D., Arbab, A. S., Sun, F., Li, C. & Yang, Z., Mar 1 2015, In : Stem Cell Research. 14, 2, p. 133-143 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population

Korkaya, H., Kim, G. I., Davis, A., Malik, F., Henry, N. L., Ithimakin, S., Quraishi, A. A., Tawakkol, N., D'Angelo, R., Paulson, A. K., Chung, S., Luther, T., Paholak, H. J., Liu, S., Hassan, K. A., Zen, Q., Clouthier, S. G. & Wicha, M. S., Aug 24 2012, In : Molecular Cell. 47, 4, p. 570-584 15 p.

Research output: Contribution to journalArticle

312 Scopus citations

Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B

Shi, L., Chen, G., Macdonald, G., Bergeron, L., Li, H., Miura, M., Rotello, R. J., Miller, D. K., Li, P., Seshadri, T., Yuan, J. & Greenberg, A. H., Oct 1 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 20, p. 11002-11007 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor

Eldredge, E. R., Korf, G. M., Christensen, T. A., Connolly, D. C., Getz, M. J. & Maihle, N. J., Nov 1994, In : Molecular and Cellular Biology. 14, 11, p. 7527-7534 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Activation of cGMP-dependent protein kinase by protein kinase C

Hou, Y., Lascola, J., Dulin, N. O., Ye, R. D. & Browning, D. D., May 9 2003, In : Journal of Biological Chemistry. 278, 19, p. 16706-16712 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., Lee, J. R., Offermanns, S. & Ganapathy, V., Jan 16 2014, In : Immunity. 40, 1, p. 128-139 12 p.

Research output: Contribution to journalArticle

724 Scopus citations

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journalArticle

33 Scopus citations
75 Scopus citations

Activation of the small GTPase Rac1 by cGMP-dependent protein kinase

Hou, Y., Ye, R. D. & Browning, D. D., Jan 1 2004, In : Cellular Signalling. 16, 9, p. 1061-1069 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Acute Depletion Redefines the Division of Labor among DNA Methyltransferases in Methylating the Human Genome

Tiedemann, R. L., Putiri, E. L., Lee, J. H., Hlady, R. A., Kashiwagi, K., Ordog, T., Zhang, Z., Liu, C., Choi, J. H. & Robertson, K. D., Nov 20 2014, In : Cell Reports. 9, 4, p. 1554-1566 13 p.

Research output: Contribution to journalArticle

28 Scopus citations

Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage

Ren, M. Q., Tidwell, J. A., Sharma, S. & Cowell, J. K., Jun 6 2012, In : PloS one. 7, 6, e38265.

Research output: Contribution to journalArticle

18 Scopus citations

Additions and Corrections: 1,3,8-Trisubstituted Xanthines. Effects of Substitution Pattern upon Adenosine Receptor A1/A2 Affinity. (Journal of Medicinal Chemistry (1991) 34(4) (1431–1435) (10.1021/jm00108a029))

Erickson, R. H., Hiner, R. N., Feeney, S. W., Blake, P. R., Rzeszotarski, W. J., Hicks, R. P., Costello, D. G. & Abreu, M. E., Dec 1 1991, In : Journal of Medicinal Chemistry. 34, 12, 1 p.

Research output: Contribution to journalComment/debate

Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells

Huang, S., Kamata, T., Takada, Y., Ruggeri, Z. M. & Nemerow, G. R., 1996, In : Journal of Virology. 70, 7, p. 4502-4508 7 p.

Research output: Contribution to journalArticle

Open Access
209 Scopus citations

Adenovirus internalization and infection require dynamin

Wang, K., Huang, S., Kapoor-Munshi, A. & Nemerow, G., Apr 1998, In : Journal of Virology. 72, 4, p. 3455-3458 4 p.

Research output: Contribution to journalArticle

Open Access
149 Scopus citations

Adenovirus technology for gene manipulation and functional studies

Wang, Y. & Huang, S., Jan 1 2000, In : Drug Discovery Today. 5, 1, p. 10-16 7 p.

Research output: Contribution to journalReview article

43 Scopus citations

Adenovirus vector pseudotyping in fiber-expressing cell lines: Improved transduction of Epstein-Barr virus-transformed B cells

Von Seggern, D. J., Huang, S., Fleck, S. K., Stevenson, S. C. & Nemerow, G. R., 2000, In : Journal of Virology. 74, 1, p. 354-362 9 p.

Research output: Contribution to journalArticle

98 Scopus citations

Adhesion-induced tyrosine phosphorylation of the p130 SRC substrate

Petch, L. A., Bockholt, S. M., Bouton, A., Parsons, J. T. & Burridge, K., 1995, In : Journal of Cell Science. 108, 4, p. 1371-1379 9 p.

Research output: Contribution to journalArticle

208 Scopus citations

Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells

Ding, Z-C., Habtetsion, T., Cao, Y., Li, T., Liu, C., Kuczma, M., Chen, T., Hao, Z., Bryan, L. J., Munn, D. H. & Zhou, G., Dec 1 2017, In : Scientific reports. 7, 1, 12168.

Research output: Contribution to journalArticle

9 Scopus citations

A facilitated tracking and transcription mechanism of long-range enhancer function

Zhu, X., Ling, J., Zhang, L., Pi, W., Wu, M. & Tuan Lo, D., Aug 2007, In : Nucleic Acids Research. 35, 16, p. 5532-5544 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

A federated network for translational cancer research using clinical data and biospecimens

Jacobson, R. S., Becich, M. J., Bollag, R. J., Chavan, G., Corrigan, J., Dhir, R., Feldman, M. D., Gaudioso, C., Legowski, E., Maihle, N. J., Mitchell, K., Murphy, M., Sakthivel, M., Tseytlin, E. & Weaver, J., Dec 15 2015, In : Cancer Research. 75, 24, p. 5194-5201 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

African Americans with pancreatic ductal adenocarcinoma exhibit gender differences in Kaiso expression

Jones, J., Mukherjee, A., Karanam, B., Davis, M., Jaynes, J., Reams, R. R., Dean-Colomb, W. & Yates, C., Oct 1 2016, In : Cancer Letters. 380, 2, p. 513-522 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

African Clinicians' Prioritization of Needs in International Breast Cancer Partnerships

Gyan, K., Kyei, I., Susick, L. L., Chen, Y., Davis, M. B., Salem, B. & Newman, L. A., Feb 2019, In : JAMA Surgery. 154, 2, p. 184-185 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

African dust and asthma in the Caribbean: Medical and statistical perspectives

Monteil, M. A. & Antoine, R., Aug 27 2009, In : International Journal of Biometeorology. 53, 5, p. 379-381 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

African dust clouds are associated with increased paediatric asthma accident and emergency admissions on the Caribbean island of Trinidad

Gyan, K., Henry, W., Lacaille, S., Laloo, A., Lamsee-Ebanks, C., McKay, S., Antoine, R. M. & Monteil, M. A., Jul 1 2005, In : International Journal of Biometeorology. 49, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

113 Scopus citations

A garter snake transcriptome: Pyrosequencing, de novo assembly, and sex-specific differences

Schwartz, T. S., Tae, H., Yang, Y., Mockaitis, K., Van Hemert, J. L., Proulx, S. R., Choi, J. H. & Bronikowski, A. M., Dec 7 2010, In : BMC Genomics. 11, 1, 694.

Research output: Contribution to journalArticle

53 Scopus citations

A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin

Jagadeeswaran, P., Tuan, D., Forget, B. G. & Weissman, S. M., Dec 1 1982, In : Nature. 296, 5856, p. 469-470 2 p.

Research output: Contribution to journalArticle

64 Scopus citations

A genome-wide methylation study of severe vitamin d deficiency in African American adolescents

Zhu, H., Wang, X., Shi, H., Su, S., Harshfield, G. A., Gutin, B., Snieder, H. & Dong, Y., May 2013, In : Journal of Pediatrics. 162, 5, p. 1004-1009.e1

Research output: Contribution to journalArticle

52 Scopus citations

A Genome-Wide Methylation Study on Essential Hypertension in Young African American Males

Wang, X., Falkner, B., Zhu, H., Shi, H., Su, S., Xu, X., Sharma, A. K., Dong, Y., Treiber, F., Gutin, B., Harshfield, G. & Snieder, H., Jan 17 2013, In : PloS one. 8, 1, e53938.

Research output: Contribution to journalArticle

45 Scopus citations

A genome-wide methylation study on obesity: Differential variability and differential methylation

Xu, X., Su, S., Barnes, V. A., De Miguel, C., Pollock, J., Ownby, D., Shi, H., Zhu, H., Snieder, H. & Wang, X., May 2013, In : Epigenetics. 8, 5, p. 522-533 12 p.

Research output: Contribution to journalArticle

100 Scopus citations

A Genome-Wide Pooled shRNA Screen Identifies PPP2R2A as a Predictive Biomarker for the Response to ATR and CHK1 Inhibitors

Qiu, Z., Fa, P., Liu, T., Prasad, C. B., Ma, S., Hong, Z., Chan, E. R., Wang, H., Li, Z., He, K., Wang, Q. E., Williams, T. M., Yan, C., Sizemore, S. T., Narla, G. & Zhang, J., Aug 15 2020, In : Cancer Research. 80, 16, p. 3305-3318 14 p.

Research output: Contribution to journalArticle

Open Access

A glycoprotein pneumococcal conjugate vaccine primes for antibody responses to a pneumococcal polysaccharide vaccine in Gambian children

Obaro, S. K., Huo, Z., Banya, W. A. S., Henderson, D. C., Monteil, M. A., Leach, A. & Greenwood, B. M., Dec 1 1997, In : Pediatric Infectious Disease Journal. 16, 12, p. 1135-1140 6 p.

Research output: Contribution to journalArticle

72 Scopus citations