Biochemistry and Molecular Biology

Research Output

Article

A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue

Petch, L. A., Harris, J., Raymond, V. W., Blasband, A., Lee, D. C. & Earp, H. S., 1990, In : Molecular and Cellular Biology. 10, 6, p. 2973-2982 10 p.

Research output: Contribution to journalArticle

172 Scopus citations

Atypical chemokine receptor 1 (DARC/ACKR1) in breast tumors is associated with survival, circulating chemokines, tumor-infiltrating immune cells, and African ancestry

Jenkins, B. D., Martini, R. N., Hire, R., Brown, A., Bennett, B., Brown, I., Howerth, E. W., Egan, M., Hodgson, J., Yates, C., Kittles, R., Chitale, D., Ali, H., Nathanson, D., Nikolinakos, P., Newman, L., Monteil, M. & Davis, M. B., Apr 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 4, p. 690-700 11 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Augmentation in expression of activation-induced genes differentiates memory from naive CD4+ T cells and is a molecular mechanism for enhanced cellular response of memory CD4+ T cells

Liu, K., Li, Y., Prabhu, V., Young, L., Becker, K. G., Munson, P. J. & Weng, N. P., Jun 15 2001, In : Journal of Immunology. 166, 12, p. 7335-7344 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Augmentation of the anticancer activity of CYT997 in human prostate cancer by inhibiting Src activity

Teng, Y., Cai, Y., Pi, W., Gao, L. & Shay, C., Jun 12 2017, In : Journal of Hematology and Oncology. 10, 1, 118.

Research output: Contribution to journalArticle

15 Scopus citations

A Universal protein tag for delivery of SiRNA-Aptamer Chimeras

Liu, H. Y. & Gao, X., Nov 7 2013, In : Scientific reports. 3, 3129.

Research output: Contribution to journalArticle

28 Scopus citations

AU-rich-element-dependent translation repression requires the cooperation of tristetraprolin and RCK/P54

Qi, M. Y., Wang, Z. Z., Zhang, Z., Shao, Q., Zeng, A., Li, X. Q., Li, W. Q., Wang, C., Tian, F. J., Li, Q., Zou, J., Qin, Y. W., Brewer, G., Huang, S. & Jing, Q., Mar 2012, In : Molecular and Cellular Biology. 32, 5, p. 913-928 16 p.

Research output: Contribution to journalArticle

58 Scopus citations

Autocrine IL6-Mediated Activation of the STAT3-DNMT Axis Silences the TNFα-RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells

Smith, A. D., Lu, C., Payne, D., Paschall, A. V., Klement, J. D., Redd, P. S., Ibrahim, M. L., Yang, D., Han, Q., Liu, Z., Shi, H., Hartney, T. J., Nayak-Kapoor, A. & Liu, K., Aug 1 2020, In : Cancer Research. 80, 15, p. 3145-3156 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury

Jiang, M., Liu, K., Luo, J. & Dong, Z., Mar 2010, In : American Journal of Pathology. 176, 3, p. 1181-1192 12 p.

Research output: Contribution to journalArticle

272 Scopus citations

Autophosphorylation of Skeletal Muscle Myosin Light Chain Kinase

Gao, Z. H., Stull, J. T., Moomaw, C. R., Hsu, J. & Slaughter, C. A., Feb 1 1992, In : Biochemistry. 31, 26, p. 6126-6133 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

A π-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase

Medlock, A. E., Dailey, T. A., Ross, T. A., Dailey, H. A. & Lanzilotta, W. N., Nov 2 2007, In : Journal of Molecular Biology. 373, 4, p. 1006-1016 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Bacterial chemoattractant synergizes with LPS to induce inflammation via upregulating TLR4

Jiang, Y., Smith, L., Pan, W. W., Chen, X., Wang, J., Lu, X. Y., Huang, S. & Pan, Z. K., Mar 30 2016, In : International Journal of Clinical and Experimental Medicine. 9, 3, p. 6005-6013 9 p.

Research output: Contribution to journalArticle

Bacterial LPS up-regulated TLR3 expression is critical for antiviral response in human monocytes: Evidence for negative regulation by CYLD

Pan, Z. K., Fisher, C., Li, J. D., Jiang, Y., Huang, S. & Chen, L. Y., 2011, In : International Immunology. 23, 6, p. 357-364 8 p., dxr019.

Research output: Contribution to journalArticle

17 Scopus citations

B-arrestins regulate stem cell-like phenotype and response to chemotherapy in bladder cancer

Kallifatidis, G., Smith, D. K., Morera, D. S., Gao, J., Hennig, M. J., Hoy, J. J., Pearce, R. F., Dabke, I. R., Li, J., Merseburger, A. S., Kuczyk, M. A., Lokeshwar, V. B. & Lokeshwar, B. L., Apr 2019, In : Molecular cancer therapeutics. 18, 4, p. 801-811 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Baseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic response to combination therapy in children (PACTG 338)

Fiscus, S. A., Kovacs, A., Petch, L. A., Hu, C., Wiznia, A. A., Mofenson, L. M., Yogev, R., McIntosh, K., Pelton, S. I., Napravnik, S., Stanley, K. & Nachman, S. A., 2007, In : AIDS Research and Therapy. 4, 2.

Research output: Contribution to journalArticle

3 Scopus citations

B cell-intrinsic IDO1 regulates humoral immunity to T cell-independent antigens

Shinde, R., Shimoda, M., Chaudhary, K., Liu, H., Mohamed, E., Bradley, J., Kandala, S., Li, X., Liu, K. & McGaha, T. L., Sep 1 2015, In : Journal of Immunology. 195, 5, p. 2374-2382 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Bifidobacteria stabilize claudins at tight junctions and prevent intestinal barrier dysfunction in mouse necrotizing enterocolitis

Bergmann, K. R., Liu, S. X. L., Tian, R., Kushnir, A., Turner, J. R., Li, H. L., Chou, P. M., Weber, C. R. & De Plaen, I. G., May 2013, In : American Journal of Pathology. 182, 5, p. 1595-1606 12 p.

Research output: Contribution to journalArticle

97 Scopus citations

Bioimaging using the optimized nonlinear optical properties of ZnO nanoparticles

Urban, B. E., Neogi, P., Senthilkumar, K., Rajpurohit, S. K., Jagadeeshwaran, P., Kim, S., Fujita, Y. & Neogi, A., 2012, In : Selected Topics in Quantum Electronics, IEEE Journal of. 18, 4, p. 1451-1456 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Biological functions of SLC5A8, a candidate tumour suppressor

Ganapathy, V., Gopal, E., Miyauchi, S. & Prasad, P. O., Feb 1 2005, In : Biochemical Society Transactions. 33, 1, p. 237-240 4 p.

Research output: Contribution to journalArticle

73 Scopus citations

BKM1740, an acyl-tyrosine bisphosphonate amide derivative, inhibits the bone metastatic growth of human prostate cancer cells by inducing apoptosis

Seong, I. S., Gera, L., Zhau, H. E., Wei, P. Q., Iqbal, S., Johnson, N. A., Zhang, S., Zayzafoon, M., Stewart, J., Wang, R., Chung, L. W. K. & Wu, D., Oct 1 2008, In : Clinical Cancer Research. 14, 19, p. 6198-6206 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
105 Scopus citations

Blood lead levels in primary school children in Trinidad and Tobago

Rajkumar, W. S., Manohar, J., Doon, R., Siung-Chang, A., Chang-Yen, I. & Monteil, M., May 15 2006, In : Science of the Total Environment. 361, 1-3, p. 81-87 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Blood utilization for elective general surgery at the Port-of-Spain General Hospital.

Monteil, M. A. & Naraynsingh, V., Dec 1 1986, In : West Indian Medical Journal. 35, 4, p. 293-294 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

Kato, Y., Tapping, R. I., Huang, S., Watson, M. H., Ulevitch, R. J. & Lee, J. D., Oct 15 1998, In : Nature. 395, 6703, p. 713-716 4 p.

Research output: Contribution to journalArticle

337 Scopus citations

Bone marrow derived myeloid cells orchestrate antiangiogenic resistance in glioblastoma through coordinated molecular networks

Achyut, B. R., Shankar, A., Iskander, A. S. M., Ara, R., Angara, K., Zeng, P., Knight, R. A., Scicli, A. G. & Arbab, A. S., Dec 28 2015, In : Cancer Letters. 369, 2, p. 416-26 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Bone marrow-derived stromal cells (BMSCs) interact with fibroblasts in accelerating wound healing

Dulchavsky, D., Gao, X., Liu, Y. B., Deeb, D., Arbab, A. S., McIntosh, K., Dulchavsky, S. A. & Gautam, S. C., 2008, In : Journal of Investigative Surgery. 21, 5, p. 270-279 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Brief hyperglycaemia in the early pregnant rat increases fetal weight at term by stimulating placental growth and affecting placental nutrient transport

Ericsson, A., Säljö, K., Sjöstrand, E., Jansson, N., Prasad, P. D., Powell, T. L. & Jansson, T., Jun 1 2007, In : Journal of Physiology. 581, 3, p. 1323-1332 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

BRN4 is a novel driver of neuroendocrine differentiation in castration-resistant prostate cancer and is selectively released in extracellular vesicles with BRN2

Bhagirath, D., Yang, T. L., Tabatabai, Z. L., Majid, S., Dahiya, R., Tanaka, Y. & Saini, S., Nov 1 2019, In : Clinical Cancer Research. 25, 21, p. 6532-6545 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Brown adipose tissue and the genetics of obesity

Ande, S., Mar 1 2016, In : Heart and Metabolism. 69, p. 4-8 5 p.

Research output: Contribution to journalArticle

141 Scopus citations

C/EBPδ is a crucial regulator of pro-apoptotic gene expression during mammary gland involution

Thangaraju, M., Rudelius, M., Bierie, B., Raffeld, M., Sharan, S., Hennighausen, L., Huang, A. M. & Sterneck, E., Nov 2005, In : Development. 132, 21, p. 4675-4685 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

c/ebpδ null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney

Thangaraju, M., Ananth, S., Martin, P. M., Roon, P., Smith, S. B., Sterneck, E., Prasad, P. D. & Ganapathy, V., Sep 15 2006, In : Journal of Biological Chemistry. 281, 37, p. 26769-26773 5 p.

Research output: Contribution to journalArticle

56 Scopus citations

C. sakazakii activates AIM2 pathway accompanying with excessive ER stress response in mammalian mammary gland epithelium

Song, W., Sheng, L., Chen, F., Tian, Y., Li, L., Wang, G., Li, H. & Cai, Y., Mar 1 2020, In : Cell Stress and Chaperones. 25, 2, p. 223-233 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Calmodulin localization during capping and receptor-mediated endocytosis

Salisbury, J. L., Condeelis, J. S., Maihle, N. J. & Satir, P., Dec 1 1981, In : Nature. 294, 5837, p. 163-166 4 p.

Research output: Contribution to journalArticle

56 Scopus citations

CAME: Identification of chromatin accessibility from nucleosome occupancy and methylome sequencing

Piao, Y., Lee, S. K., Lee, E. J., Robertson, K. D., Shi, H., Ryu, K. H. & Choi, J. H., Apr 15 2017, In : Bioinformatics. 33, 8, p. 1139-1146 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

cAMP-responsive element-binding protein regulates vascular endothelial growth factor expression: Implication in human prostate cancer bone metastasis

Wu, D., Zhau, H. E., Huang, W. C., Iqbal, S., Habib, F. K., Sartor, O., Cvitanovic, L., Marshall, F. F., Xu, Z. & Chung, L. W. K., Aug 2 2007, In : Oncogene. 26, 35, p. 5070-5077 8 p.

Research output: Contribution to journalArticle

98 Scopus citations

Can Brown Fat Win the Battle Against White Fat?

Elattar, S. & Satyanarayana, A., Oct 1 2015, In : Journal of Cellular Physiology. 230, 10, p. 2311-2317 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta

Kenney, S. P., Kekuda, R., Prasad, P. D., Leibach, F. H., Devoe, L. D. & Ganapathy, V., Jan 1 1999, In : American Journal of Obstetrics and Gynecology. 181, 2, p. 491-497 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Canonical NFκB signaling in myeloid cells is required for the glioblastoma growth

Achyut, B. R., Angara, K., Jain, M., Borin, T. F., Rashid, M. H., Iskander, A. S. M., Ara, R., Kolhe, R., Howard, S., Venugopal, N., Rodriguez, P. C., Bradford, J. W. & Arbab, A. S., Dec 1 2017, In : Scientific reports. 7, 1, 13754.

Research output: Contribution to journalArticle

8 Scopus citations

Canonical wnt signaling in CD11c + APCs regulates microbiota-Induced inflammation and immune cell homeostasis in the colon

Swafford, D., Shanmugam, A., Ranganathan, P., Hussein, M. S., Koni, P. A., Prasad, P. D., Thangaraju, M. & Manicassamy, S., May 1 2018, In : Journal of Immunology. 200, 9, p. 3259-3268 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Canonical Wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation

Suryawanshi, A., Manoharan, I., Hong, Y., Swafford, D., Majumdar, T., Taketo, M. M., Manicassamy, B., Koni, P. A., Thangaraju, M., Sun, Z., Mellor, A. L., Munn, D. H. & Manicassamy, S., Apr 1 2015, In : Journal of Immunology. 194, 7, p. 3295-3304 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Capillary electrophoresis determination of biflavanones from Garcinia kola in three traditional African medicinal formulations

Okunji, C. O., Ware, T. A., Hicks, R. P., Iwu, M. M. & Skanchy, D. J., Jun 19 2002, In : Planta Medica. 68, 5, p. 440-444 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Carbon monoxide releasing molecule A-1 attenuates acetaminophen-mediated hepatotoxicity and improves survival of mice by induction of Nrf2 and related genes

Upadhyay, K. K., Jadeja, R. N., Thadani, J. M., Joshi, A., Vohra, A., Mevada, V., Patel, R., Khurana, S. & Devkar, R. V., Dec 1 2018, In : Toxicology and Applied Pharmacology. 360, p. 99-108 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function

Upadhyay, K. K., Jadeja, R. N., Vyas, H. S., Pandya, B., Joshi, A., Vohra, A., Thounaojam, M. C., Martin, P. M., Bartoli, M. & Devkar, R. V., Jan 2020, In : Redox Biology. 28, 101314.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family

Wang, Y., Huang, S., Sah, V. P., Ross, J., Brown, J. H., Han, J. & Chien, K. R., Jan 23 1998, In : Journal of Biological Chemistry. 273, 4, p. 2161-2168 8 p.

Research output: Contribution to journalArticle

724 Scopus citations

Carvedilol-responsive microRNAs, miR-199a-3p and -214 protect cardiomyocytes from simulated ischemia-reperfusion injury

Park, K. M., Teoh, J. P., Wang, Y., Broskova, Z., Bayoumi, A. S., Tang, Y. L., Su, H., Weintraub, N. L. & Kim, I., Aug 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 2, p. H371-H383

Research output: Contribution to journalArticle

38 Scopus citations

Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelope

Wu, J., Jiang, H., Luo, S., Zhang, M., Zhang, Y., Sun, F., Huang, S. & Li, H., May 2013, In : Cell Research. 23, 5, p. 691-704 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

CD133+CD24lo defines a 5-Fluorouracil-resistant colon cancer stem cell-like phenotype

Paschall, A. V., Yang, D., Lu, C., Redd, P. S., Choi, J. H., Heaton, C. M., Lee, J. R., Nayak-Kapoor, A. & Liu, K., 2016, In : Oncotarget. 7, 48, p. 78698-78712 15 p.

Research output: Contribution to journalArticle

16 Scopus citations

CD38 deficiency promotes inflammatory response through activating sirt1/NF-κB-mediated inhibition of TLR2 expression in macrophages

Qian, Y., Chen, C., Ma, L., Wang, Z., Wang, L. F., Zuo, L., Yang, Y., Huang, X., Jiang, M., Wang, X., Shi, H., Fu, M., Deng, K. Y. & Xin, H. B., 2018, In : Mediators of Inflammation. 2018, 8736949.

Research output: Contribution to journalArticle

4 Scopus citations

CD4+CD25+ regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis

Singh, N., Yamamoto, M., Takami, M., Seki, Y., Takezaki, M., Mellor, A. L. & Iwashima, M., Jan 1 2010, In : Journal of Immunology. 184, 1, p. 94-104 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint

Yu, M., Guo, G., Huang, L., Deng, L., Chang, C. S., Achyut, B. R., Canning, M., Xu, N., Arbab, A. S., Bollag, R. J., Rodriguez, P. C., Mellor, A. L., Shi, H., Munn, D. H. & Cui, Y., Dec 1 2020, In : Nature communications. 11, 1, 515.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations