Biochemistry and Molecular Biology

Research Output

Article

c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms

Sakamuro, D., Eviner, V., Elliott, K. J., Showe, L., White, E. & Prendergast, G. C., Dec 7 1995, In : Oncogene. 11, 11, p. 2410-2418 9 p.

Research output: Contribution to journalArticle

154 Scopus citations

Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3

Thangaraju, M., Carswell, K. N., Prasad, P. D. & Ganapathy, V., Jan 1 2009, In : Biochemical Journal. 417, 1, p. 379-389 11 p.

Research output: Contribution to journalArticle

99 Scopus citations

Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8

Cresci, G. A., Thangaraju, M., Mellinger, J. D., Liu, K. & Ganapathy, V., Mar 1 2010, In : Journal of Gastrointestinal Surgery. 14, 3, p. 449-461 13 p.

Research output: Contribution to journalArticle

85 Scopus citations

Combination of transfection agents and magnetic resonance contrast agents for cellular imaging: Relationship between relaxivities, electrostatic forces, and chemical composition

Kalish, H., Arbab, A. S., Miller, B. R., Lewis, B. K., Zywicke, H. A., Bulte, J. W. M., Bryant, L. H. & Frank, J. A., Aug 1 2003, In : Magnetic Resonance in Medicine. 50, 2, p. 275-282 8 p.

Research output: Contribution to journalArticle

119 Scopus citations

Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma

Shankar, A., Borin, T. F., Iskander, A., Varma, N. R. S., Achyut, B. R., Jain, M., Mikkelsen, T., Guo, A. M., Chwang, W. B., Ewing, J. R., Bagher-Ebadian, H. & Arbab, A. S., Mar 9 2016, In : OncoTargets and Therapy. 9, p. 1205-1219 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

Fiskus, W., Wang, Y., Sreekumar, A., Buckley, K. M., Shi, H., Jillella, A., Ustun, C., Rao, R., Fernandez, P., Chen, J., Balusu, R., Koul, S., Atadja, P., Marquez, V. E. & Bhalla, K. N., 2009, In : Blood. 114, 13, p. 2733-2743 11 p.

Research output: Contribution to journalArticle

269 Scopus citations

Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth

Pathania, R., Ramachandran, S., Mariappan, G., Thakur, P., Shi, H., Choi, J. H., Manicassamy, S., Kolhe, R., Prasad, P. D., Sharma, S., Lokeshwar, B. L., Ganapathy, V. & Thangaraju, M., Jun 1 2016, In : Cancer Research. 76, 11, p. 3224-3235 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues

Blackburn, A. R., Hamrick, M. W., Chutkan, N., Sangani, R., Waller, J. L., Corpe, R., Prasad, P. D., Isales, C. M., Ganapathy, V. & Fulzele, S., Jan 8 2014, In : BMC Musculoskeletal Disorders. 15, 1, 9.

Research output: Contribution to journalArticle

1 Scopus citations

Comparing mRNA levels of genes encoding leptin, leptin receptor, and lipoprotein lipase between dairy and beef cattle

Ren, M. Q., Wegner, J., Bellmann, O., Brockmann, G. A., Schneider, F., Teuscher, F. & Ender, K., Oct 1 2002, In : Domestic Animal Endocrinology. 23, 3, p. 371-381 11 p.

Research output: Contribution to journalArticle

49 Scopus citations

Comparison of prevalence and severity of asthma among adolescents in the Caribbean islands of Trinidad and Tobago: Results of a nationwide cross-sectional survey

Monteil, M. A., Joseph, G., Changkit, C., Wheeler, G. & Antoine, R. M., Sep 14 2005, In : BMC public health. 5, 96.

Research output: Contribution to journalArticle

17 Scopus citations

Comparison of the conformation and electrostatic surface properties of magainin peptides bound to sodium dodecyl sulfate and dodecylphosphocholine micelles

Hicks, R. P., Mones, E., Kim, H., Koser, B. W., Nichols, D. A. & Bhattacharjee, A. K., Apr 1 2003, In : Biopolymers. 68, 4, p. 459-470 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Competitive ubiquitination activates the tumor suppressor p53

Li, X., Guo, M., Cai, L., Du, T., Liu, Y., Ding, H. F., Wang, H., Zhang, J., Chen, X. & Yan, C., Jun 1 2020, In : Cell Death and Differentiation. 27, 6, p. 1807-1818 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Complete distal renal tubular acidosis: Biochemical profile of a case

Rajpurohit, S. K., Pendse, AK., Ahmed, A. & Singh, PP., 1992, In : Indian Journal of Clinical Biochemistry. 7, 2, p. 205-206 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Complete genome sequence and analysis of the industrial Saccharomyces cerevisiae strain N85 used in Chinese rice wine production

Zhang, W., Li, Y., Chen, Y., Xu, S., Du, G., Shi, H., Zhou, J. & Chen, J., 2018, In : DNA Research. 25, 3, p. 297-306 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Computational methods for detection of differentially methylated regions using kernel distance and scan statistics

Dunbar, F., Xu, H., Ryu, D., Ghosh, S., Shi, H. & George, V., Apr 2019, In : Genes. 10, 4, 298.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Concentration-independent MRI of pH with a dendrimer-based pH-responsive nanoprobe

Bhuiyan, M. P. I., Aryal, M. P., Janic, B., Karki, K., Varma, N. R. S., Ewing, J. R., Arbab, A. S. & Ali, M. M., Nov 1 2015, In : Contrast Media and Molecular Imaging. 10, 6, p. 481-486 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Concurrent PD-1 blockade negates the effects of OX40 agonist antibody in combination immunotherapy through inducing T-cell apoptosis

Shrimali, R. K., Ahmad, S., Verma, V., Zeng, P., Ananth, S., Gaur, P., Gittelman, R. M., Yusko, E., Sanders, C., Robins, H., Hammond, S. A., Janik, J. E., Mkrtichyan, M., Gupta, S. & Khleif, S. N., Sep 2017, In : Cancer Immunology Research. 5, 9, p. 755-766 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

Conformational analysis of met‐enkephalin in both aqueous solution and in the presence of sodium dodecyl sulfate micelles using multidimensional NMR and molecular modeling

Graham, W. H., Carter, E. S. & Hicks, R. P., Jan 1 1992, In : Biopolymers. 32, 12, p. 1755-1764 10 p.

Research output: Contribution to journalArticle

103 Scopus citations

Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease

Ren, M. Q. & Cowell, J. K., Jun 23 2011, In : Blood. 117, 25, p. 6837-6847 11 p.

Research output: Contribution to journalArticle

29 Scopus citations
17 Scopus citations

Contributions of viral splice sites and cis-regulatory elements to lentivirus vector function

Cui, Y., Iwakuma, T. & Chang, L. J., 1999, In : Journal of Virology. 73, 7, p. 6171-6176 6 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Control of AKR fibroblast phenotype by fibronectin: Regulation of cell‐surface fibronectin binding receptor by fibronectin

Huang, S., Varani, J. & Chakrabarty, S., Dec 1994, In : Journal of Cellular Physiology. 161, 3, p. 470-482 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Control of fibronectin receptor expression by fibronectin: Antisense fibronectin RNA downmodulates the induction of fibronectin receptor by transforming growth factor β1

Rajagopal, S., Huang, S., Albitar, M. & Chakrabarty, S., Feb 1997, In : Journal of Cellular Physiology. 170, 2, p. 138-144 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

COP1 and GSK3β cooperate to promote c-Jun degradation and inhibit breast cancer cell tumorigenesis

Shao, J., Teng, Y., Padia, R., Hong, S., Noh, H., Xie, X., Mumm, J. S., Dong, Z., Ding, H. F., Cowell, J., Kim, J., Han, J. & Huang, S., Sep 2013, In : Neoplasia (United States). 15, 9, p. 1075-1085 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Co-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer

Liu, H., Yu, X., Liu, H., Wu, D. & She, J-X., Jul 26 2016, In : Scientific reports. 6, 30346.

Research output: Contribution to journalArticle

32 Scopus citations

Cotransfer of circular and linear prokaryotic and eukaryotic DNA sequences into mouse cells.

Hsiung, N., Warrick, H., deRiel, J. K., Tuan, D., Forget, B. G., Skoultchi, A. & Kucherlapati, R., Aug 1980, In : Proceedings of the National Academy of Sciences of the United States of America. 77, 8, p. 4852-4856 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Creation of EcR isoform-specific mutations in Drosophila melanogaster via local P element transposition, imprecise P element excision, and male recombination

Carney, G. E., Robertson, A., Davis, M. B. & Bender, M., Apr 1 2004, In : Molecular Genetics and Genomics. 271, 3, p. 282-290 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome

Chong, Y., Liu, Y., Lu, S., Cai, B., Qin, H., Chang, C. S., Ren, M., Cowell, J. K. & Hu, T., Apr 15 2020, In : International Journal of Cancer. 146, 8, p. 2243-2254 12 p.

Research output: Contribution to journalArticle

Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization

Stewart, P. L., Chiu, C. Y., Huang, S., Muir, T., Zhao, Y., Chait, B., Mathias, P. & Nemerow, G. R., Mar 17 1997, In : EMBO Journal. 16, 6, p. 1189-1198 10 p.

Research output: Contribution to journalArticle

137 Scopus citations

Cryptotanshinone inhibits esophageal squamous-cell carcinoma in vitro and in vivo through the suppression of STAT3 activation

Ji, Y., Liu, Y., Xue, N., Du, T., Wang, L., Huang, R., Li, L., Yan, C. & Chen, X., 2019, In : OncoTargets and Therapy. 12, p. 883-896 14 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Curcumin analogue UBS109 prevents bone loss in breast cancer bone metastasis mouse model: Involvement in osteoblastogenesis and osteoclastogenesis

Yamaguchi, M., Zhu, S., Zhang, S., Wu, D., Moore, T. M., Snyder, J. P. & Shoji, M., Jul 2014, In : Cell and Tissue Research. 357, 1, p. 245-252 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects

Zhou, Q. M., Wang, X. F., Liu, X. J., Zhang, H., Lu, Y. Y., Huang, S. & Su, S. B., Sep 1 2011, In : European Journal of Cancer. 47, 14, p. 2240-2247 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Curcumin improves the tumoricidal effect of mitomycin C by suppressing ABCG2 expression in stem cell-like breast cancer cells

Zhou, Q., Ye, M., Lu, Y., Zhang, H., Chen, Q., Huang, S. & Su, S., Aug 25 2015, In : PloS one. 10, 8, e0136694.

Research output: Contribution to journalArticle

36 Scopus citations

Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets

Jain, A., Samykutty, A., Jackson, C., Browning, D., Bollag, W. B., Thangaraju, M., Takahashi, S. & Singh, S. R., Aug 28 2015, In : Cancer Letters. 365, 1, p. 122-131 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cutting edge: IRF8 regulates bax transcription in vivo in primary myeloid cells

Yang, J., Hu, X., Zimmerman, M., Torres, C. M., Yang, D., Smith, S. B. & Liu, K., Nov 1 2011, In : Journal of Immunology. 187, 9, p. 4426-4430 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma

Angara, K., Borin, T. F., Rashid, M. H., Lebedyeva, I., Ara, R., Lin, P. C., Iskander, A. S. M., Bollag, R. J., Achyut, B. R. & Arbab, A. S., Oct 2018, In : Neoplasia (United States). 20, 10, p. 1070-1082 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Cyclic 3′,5′-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia

Kwon, I. K., Wang, R., Prakash, N., Bozard, R., Baudino, T. A., Liu, K., Thangaraju, M., Dong, Z. & Browning, D. D., Dec 1 2011, In : Cancer. 117, 23, p. 5282-5293 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cyclic-GMP-elevating agents suppress polyposis in Apc Min mice by targeting the preneoplastic epithelium

Sharman, S. K., Islam, B. N., Hou, Y., Singh, N., Berger, F. G., Sridhar, S., Yoo, W. & Browning, D. D., Feb 2018, In : Cancer Prevention Research. 11, 2, p. 81-91 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression

Yang, L., Fang, D., Chen, H., Lu, Y., Dong, Z., Ding, H. F., Jing, Q., Su, S. B. & Huang, S., 2015, In : Oncotarget. 6, 25, p. 20801-20812 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression

Mao, L., Ding, J., Perdue, A., Yang, L., Zha, Y., Ren, M., Huang, S., Cui, H. & Ding, H. F., Aug 16 2012, In : Oncogene. 31, 33, p. 3785-3795 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells

Chen, L., Tang, S., Zhang, F. F., Garcia, V., Falck, J. R., Schwartzman, M. L., Arbab, A. S. & Guo, A. M., Jun 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 6, p. H1468-H1479

Research output: Contribution to journalArticle

1 Scopus citations

Cystathionine beta synthase expression in mouse retina

Markand, S., Tawfik, A., Ha, Y., Gnana-Prakasam, J., Sonne, S., Ganapathy, V., Sen, N., Xian, M. & Smith, S. B., May 2013, In : Current Eye Research. 38, 5, p. 597-604 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cysteine redox sensor in PKGIα enables oxidant-induced activation

Burgoyne, J. R., Madhani, M., Cuello, F., Charles, R. L., Brennan, J. P., Schröder, E., Browning, D. D. & Eaton, P., Sep 7 2007, In : Science. 317, 5843, p. 1393-1397 5 p.

Research output: Contribution to journalArticle

337 Scopus citations

Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis

Liu, H. Y., Zheng, G., Treber, M., Dai, J. & Woldegiorgis, G., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 4524-4531 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Cytochrome p450 1B1 polymorphisms and risk of renal cell carcinoma in men

Chang, I., Fukuhara, S., Wong, D. K., Gill, A., Mitsui, Y., Majid, S., Saini, S., Yamamura, S., Chiyomaru, T., Hirata, H., Ueno, K., Arora, S., Shahryari, V., Deng, G., Laura Tabatabai, Z., Greene, K. L., Shin, D. M., Enokida, H., Shiina, H., Nonomura, N. & 2 others, Dahiya, R. & Tanaka, Y., 2014, In : Tumor Biology. 35, 10, p. 10223-10230 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer

Pejovic, T., Yates, J. E., Liu, H. Y., Hays, L. E., Akkari, Y., Torimaru, Y., Keeble, W., Rathbun, R. K., Rodgers, W. H., Bale, A. E., Ameziane, N., Zwaan, C. M., Errami, A., Thuillier, P., Cappuccini, F., Olson, S. B., Cain, J. M. & Bagby, G. C., Sep 15 2006, In : Cancer Research. 66, 18, p. 9017-9025 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In : International journal of molecular sciences. 19, 2, 577.

Research output: Contribution to journalArticle

2 Scopus citations

Cytokine gene polymorphisms and the pathology of chronic gastritis

Moorchung, N., Srivastava, A. N., Gupta, N. K., Ghoshal, U. C., Achyut, B. R. & Mittal, B., May 2007, In : Singapore Medical Journal. 48, 5, p. 447-54 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
Open Access
1 Scopus citations

Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Jadeja, R. N., Urrunaga, N. H., Ahmad, D. & Khurana, S., Mar 1 2016, In : Data in Brief. 6, p. 405-409 5 p.

Research output: Contribution to journalArticle

1 Scopus citations