Biochemistry and Molecular Biology

Research Output

Article

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells

Putiri, E. L., Tiedemann, R. L., Thompson, J. J., Liu, C., Ho, T., Choi, J. H. & Robertson, K. D., Jun 23 2014, In : Genome Biology. 15, 6, R81.

Research output: Contribution to journalArticle

56 Scopus citations

Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome

Silva, M. J., Chang, C. S., Hu, T., Qin, H., Kitamura, E., Hawthorn, L., Ren, M. & Cowell, J. K., Dec 2019, In : Genomics. 111, 6, p. 1566-1573 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Distinct transcript isoforms of the atypical chemokine receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) gene are expressed in lymphoblasts and altered isoform levels are associated with genetic ancestry and the duffy-null allele

Davis, M. B., Walens, A., Hire, R., Mumin, K., Brown, A. M., Ford, D. J., Howerth, E. W. & Monteil, M., Oct 16 2015, In : PloS one. 10, 10, 140098.

Research output: Contribution to journalArticle

8 Scopus citations

Distribution and Short-term Prognostic Value of the 21-gene recurrence score in African American compared to White American breast cancer patients

Amro, A., Chen, Y., Barry, R., Susick, L., Bensenhaver, J., Proctor, E., Petersen, L., Nathanson, S. D., Ali, H., Loutfi, R., Chitale, D., Simonds, A., Kuklinski, M., Park, K. U., Davis, M. & Newman, L. A., Jul 1 2019, In : Breast Journal. 25, 4, p. 667-671 5 p.

Research output: Contribution to journalArticle

Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells

Bachmann, A., Hanke, B., Zawatzky, R., Soto, U., Van Riggelen, J., Zur Hausen, H. & Rösl, F., 2002, In : Journal of Virology. 76, 1, p. 280-291 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma

Bennett, L. B., Schnabel, J. L., Kelchen, J. M., Taylor, K. H., Guo, J., Arthur, G. L., Papageorgio, C. N., Shi, H. & Caldwell, C. W., Sep 2009, In : Genes Chromosomes and Cancer. 48, 9, p. 828-841 14 p.

Research output: Contribution to journalArticle

52 Scopus citations

DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes, including interferon regulatory factor 8

Guo, C., Pei, L., Xiao, X., Wei, Q., Chen, J., Ding, H., Huang, S., Fan, G., Shi, H. & Dong, Z., Nov 2017, In : Kidney International. 92, 5, p. 1194-1205 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

DNA methylation represses IFN-γ-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells

McGough, J. M., Yang, D., Huang, S., Georgi, D., Hewitt, S. M., Röcken, C., Tänzer, M., Ebert, M. P. A. & Liu, K., Dec 1 2008, In : Molecular Cancer Research. 6, 12, p. 1841-1851 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

DNA methyltransferase 1–mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1– driven leukemogenesis

Hu, T., Chong, Y., Cai, B., Liu, Y., Lu, S. & Cowell, J. K., Nov 29 2019, In : Journal of Biological Chemistry. 294, 48, p. 18122-18130 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells

Fukuhara, S., Chang, I., Mitsui, Y., Chiyomaru, T., Yamamura, S., Majid, S., Saini, S., Hirata, H., Deng, G., Gill, A., Wong, D. K., Shiina, H., Nonomura, N., Dahiya, R. & Tanaka, Y., 2014, In : Oncotarget. 5, 22, p. 11297-11307 11 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

Pathania, R., Ramachandran, S., Elangovan, S., Padia, R., Yang, P., Cinghu, S., Veeranan-Karmegam, R., Arjunan, P., Gnana-Prakasam, J. P., Sadanand, F., Pei, L., Chang, C. S., Choi, J. H., Shi, H., Manicassamy, S., Prasad, P. D., Sharma, S., Ganapathy, V., Jothi, R. & Thangaraju, M., Apr 22 2015, In : Nature communications. 6, 6910.

Research output: Contribution to journalArticle

117 Scopus citations

DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma

Poole, C. J., Zheng, W., Lodh, A., Yevtodiyenko, A., Liefwalker, D., Li, H., Felsher, D. W. & van Riggelen, J., 2017, In : Oncotarget. 8, 44, p. 76898-76920 23 p.

Research output: Contribution to journalArticle

16 Scopus citations

Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation

Leu, Y. W., Rahmatpanah, F., Shi, H., Wei, S. H., Liu, J. C., Yan, P. S. & Huang, T. H. M., Oct 1 2003, In : Cancer Research. 63, 19, p. 6110-6115 6 p.

Research output: Contribution to journalArticle

128 Scopus citations

Down-regulation of BCRP/ABCG2 in colorectal and cervical cancer

Gupta, N., Martin, P. M., Miyauchi, S., Ananth, S., Herdman, A. V., Martindale, R. G., Podolsky, R. & Ganapathy, V., May 5 2006, In : Biochemical and Biophysical Research Communications. 343, 2, p. 571-577 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Downregulation of IFN-γR in association with loss of Fas function is linked to tumor progression

Yang, D., Stewart, T. J., Smith, K. K., Georgi, D., Abrams, S. I. & Liu, K., Jan 15 2008, In : International Journal of Cancer. 122, 2, p. 350-362 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice

Naggar, H., Shamsul Ola, M., Martin, P. M., Huang, W., Bridges, C. C., Ganapathy, V. & Smith, S. B., 2002, In : Investigative Ophthalmology and Visual Science. 43, 2, p. 556-563 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
Open Access
14 Scopus citations

Draft genome sequence of a novel rhabdovirus isolated from Deinocerites mosquitoes

Xu, C. L., Cantalupo, P. G., Sáenz-Robles, M. T., Baldwin, A., Fitzpatrick, D., Norris, D. E., Jackson, E. & Pipas, J. M., May 1 2018, In : Genome Announcements. 6, 19, e01438-17.

Research output: Contribution to journalArticle

2 Scopus citations

Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis

Cho, S. G., Du, Q., Huang, S. & Dong, Z., Jul 2010, In : American Journal of Physiology - Renal Physiology. 299, 1, p. F199-F206

Research output: Contribution to journalArticle

53 Scopus citations

Drugs of abuse and placental transport

Ganapathy, V., Prasad, P. D., Ganapathy, M. E. & Leibach, F. H., Jun 14 1999, In : Advanced Drug Delivery Reviews. 38, 1, p. 99-110 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy

Wang, Q., Navitskaya, S., Chakravarthy, H., Huang, C., Kady, N., Lydic, T. A., Chen, Y. E., Yin, K. J., Powell, F. L., Martin, P. M., Grant, M. B. & Busik, J. V., Sep 1 2016, In : EBioMedicine. 11, p. 138-150 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway

Zhang, L. N., Karp, P., Gerard, C. J., Pastor, E., Laux, D., Munson, K., Yan, Z., Liu, X., Godwin, S., Thomas, C. P., Zabner, J., Shi, H., Caldwell, C. W., Peluso, R., Carter, B. & Engelhardt, J. F., Dec 2004, In : Molecular Therapy. 10, 6, p. 990-1002 13 p.

Research output: Contribution to journalArticle

34 Scopus citations

Dynamic changes in the locus control region of erythroid progenitor cells demonstrated by polymerase chain reaction

Yoo, J., Herman, L. E., Li, C., Krantz, S. B. & Tuan Lo, D., Mar 15 1996, In : Blood. 87, 6, p. 2558-2567 10 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma

Tiedemann, R. L., Hlady, R. A., Hanavan, P. D., Lake, D. F., Tibes, R., Lee, J. H., Choi, J. H., Ho, T. H. & Robertson, K. D., 2016, In : Oncotarget. 7, 2, p. 1927-1946 20 p.

Research output: Contribution to journalArticle

28 Scopus citations

Dynamic retrotransposition of ERV-9 LTR and L1 in the β-globin gene locus during primate evolution

Ling, J., Zhang, L., Jin, H., Pi, W., Kosteas, T., Anagnou, N. P., Goodman, M. & Tuan, D., Mar 2004, In : Molecular Phylogenetics and Evolution. 30, 3, p. 867-871 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Dysplastic hepatocytes develop nuclear inclusions in a mouse model of viral hepatitis

Thakur, P., Lamoke, F., Chaffin, J. M., Bartoli, M., Lee, J. R. & Duncan, M. B., Jun 16 2014, In : PloS one. 9, 6, e99872.

Research output: Contribution to journalArticle

5 Scopus citations

Dysregulated signaling pathways in the development of CNTRL-FGFR1–induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models

Ren, M., Qin, H., Kitamura, E. & Cowell, J. K., Aug 8 2013, In : Blood. 122, 6, p. 1007-1016 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

E-Cadherin Engagement Stimulates Tyrosine Phosphorylation

Kinch, M. S., Petch, L., Zhong, C. & Burridge, K., 1997, In : Cell Communication and Adhesion. 4, 6, p. 425-437 13 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Ectopic expression of nonliganded retinoic acid receptor β abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells

Arce, J. D. C., Soto, U., Van Riggelen, J., Schwarz, E., Zur Hausen, H. & Rösl, F., Oct 29 2004, In : Journal of Biological Chemistry. 279, 44, p. 45408-45416 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effectiveness of potassium citrate therapy in the management of nephrolithiasis

Rajpurohit, S. K., Pendse, AK., Barjatiya, MK. & Singh, PP., 1996, In : Urolithiasis. p. 450

Research output: Contribution to journalArticle

Effect of curcumin on pro-angiogenic factors in the xenograft model of breast cancer

Ferreira, L. C., Arbab, A. S., Jardim-Perassi, B. V., Borin, T. F., Varma, N. R. S., Iskander, A. S. M., Shankar, A., Ali, M. M. & de Campos Zuccari, D. A. P., Dec 1 2015, In : Anti-Cancer Agents in Medicinal Chemistry. 15, 10, p. 1285-1296 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Effect of high fat diet on body weight and mammary tumor latency in MMTV-TGF-α mice

Cleary, M. P., Grande, J. P. & Maihle, N. J., Aug 1 2004, In : International Journal of Obesity. 28, 8, p. 956-962 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Effect of melatonin on tumor growth and angiogenesis in xenograft model of breast cancer

Jardim-Perassi, B. V., Arbab, A. S., Ferreira, L. C., Borin, T. F., Varma, N. R. S., Iskander, A. S. M., Shankar, A., Ali, M. M. & De Campos Zuccari, D. A. P., Jan 9 2014, In : PloS one. 9, 1, e85311.

Research output: Contribution to journalArticle

99 Scopus citations

Effect of moderate caloric restriction and/or weight cycling on mammary tumor incidence and latency in MMTV-Neu female mice

Pape-Ansorge, K. A., Grande, J. P., Christensen, T. A., Maihle, N. J. & Cleary, M. P., 2002, In : Nutrition and Cancer. 44, 2, p. 162-168 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Effect of α-domain substitution on the structure, property and function of human neuronal growth inhibitory factor

Ding, Z-C., Zheng, Q., Cai, B., Yu, W. H., Teng, X. C., Wang, Y., Zhou, G. M., Wu, H. M., Sun, H. Z., Zhang, M. J. & Huang, Z. X., Nov 1 2007, In : Journal of Biological Inorganic Chemistry. 12, 8, p. 1173-1179 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice

Dogan, S., Hu, X., Zhang, Y., Maihle, N. J., Grande, J. P. & Cleary, M. P., Dec 27 2007, In : Breast Cancer Research. 9, 6, R91.

Research output: Contribution to journalArticle

64 Scopus citations

Effects of modulating M3 muscarinic receptor activity on azoxymethane-induced liver injury in mice

Khurana, S., Jadeja, R., Twaddell, W., Cheng, K., Rachakonda, V., Saxena, N. & Raufman, J. P., 2013, In : Biochemical Pharmacology. 86, 2, p. 329-338 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Effects of novel polyether ionophore hainanmycin on nutrient digestion, metabolism and ruminal characteristics of goats

Mingqiang, R., Zanming, S., Ruqian, Z., Tianshui, L. & Jie, C., Jan 1 1998, In : Journal of Animal and Feed Sciences. 7, 1, p. 21-28 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effects of targeted Bcl-2 expression in mitochondria or endoplasmic reticulum on renal tubular cell apoptosis

Bhatt, K., Feng, L., Pabla, N., Liu, K., Smith, S. & Dong, Z., Mar 2008, In : American Journal of Physiology - Renal Physiology. 294, 3, p. F499-F507

Research output: Contribution to journalArticle

38 Scopus citations

Effects of the incorporation of CHAPS into SDS micelles on neuropeptide-micelle binding: Separation of the role of electrostatic interactions from hydrophobic interactions

Whitehead, T. L., Jones, L. M. & Hicks, R. P., Jun 11 2001, In : Biopolymers. 58, 7, p. 593-605 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Effects of tyrosine kinase inhibitors and CXCR4 antagonist on tumor growth and angiogenesis in rat glioma model: MRI and protein analysis study

Ali, M. M., Kumar, S., Shankar, A., Varma, N. R. S., Iskander, A. S. M., Janic, B., Chwang, W. B., Jain, R., Babajeni-Feremi, A., Borin, T. F., Bagher-Ebadian, H., Brown, S. L., Ewing, J. R. & Arbab, A. S., Dec 2013, In : Translational Oncology. 6, 6, p. 660-669 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system

Chang, L. J., Urlacher, V., Iwakuma, T., Cui, Y. & Zucali, J., May 1 1999, In : Gene Therapy. 6, 5, p. 715-728 14 p.

Research output: Contribution to journalArticle

177 Scopus citations

Efficacy of melatonin, IL-25 and siIL-17B in tumorigenesis-associated properties of breast cancer cell lines

Gelaleti, G. B., Borin, T. F., Maschio-Signorini, L. B., Moschetta, M. G., Jardim-Perassi, B. V., Calvinho, G. B., Facchini, M. C., Viloria-Petit, A. M. & de Campos Zuccari, D. A. P., Aug 15 2017, In : Life sciences. 183, p. 98-109 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

EGF receptor/ErbB isoforms as serum biomarkers in breast and ovarian cancer

Maihle, N. J., Lafky, J. M., Baron, A. T., Boardman, C. H., Greenwood, T. M., Christensen, T. A., Reiter, J. L., Cora, E. M., Lee, H., Suman, V. J., Fishman, D. A., Perez, E. A. & Podratz, K. C., Mar 1 2002, In : Journal of Clinical Ligand Assay. 25, 1, p. 57-60 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

EGFR isoforms and gene regulation in human endometrial cancer cells

Albitar, L., Pickett, G., Morgan, M., Wilken, J. A., Maihle, N. J. & Leslie, K. K., Jun 25 2010, In : Molecular cancer. 9, 166.

Research output: Contribution to journalArticle

31 Scopus citations

Electrochemical Detection of Alginate Penetration in Immobilized Layer-by-Layer Films by Unnatural Amino Acid Containing Antimicrobial Peptides

Vinogradov, S. M., Satterwhite-Warden, J. E., Hicks, R. P., Anderson, E. & Hvastkovs, E. G., Dec 20 2015, In : Electrochimica Acta. 186, p. 245-252 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Electrogenic nature of rat sodium-dependent multivitamin transport

Prasad, P. D., Srinivas, S. R., Wang, H., Leibach, F. H., Devoe, L. D. & Ganapathy, V., Apr 21 2000, In : Biochemical and Biophysical Research Communications. 270, 3, p. 836-840 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis

Tian, F. J., An, L. N., Wang, G. K., Zhu, J. Q., Li, Q., Zhang, Y. Y., Zeng, A., Zou, J., Zhu, R. F., Han, X. S., Shen, N., Yang, H. T., Zhao, X. X., Huang, S., Qin, Y. W. & Jing, Q., Jul 1 2014, In : Cardiovascular Research. 103, 1, p. 100-110 11 p.

Research output: Contribution to journalArticle

96 Scopus citations

Elevated serum levels of transforming growth factor-α in breast cancer patients

Chakrabarty, S., Huang, S., Moskal, T. L. & Fritsche, H. A., May 16 1994, In : Cancer Letters. 79, 2, p. 157-160 4 p.

Research output: Contribution to journalArticle

27 Scopus citations