Biochemistry and Molecular Biology

Research Output

Article

Elevated urokinase-specific surface receptor expression is maintained through its interaction with urokinase plasminogen activator

Mahanivong, C., Yu, J. & Huang, S., Mar 2007, In : Molecular Carcinogenesis. 46, 3, p. 165-175 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy

Paholak, H. J., Stevers, N. O., Chen, H., Burnett, J. P., He, M., Korkaya, H., McDermott, S. P., Deol, Y., Clouthier, S. G., Luther, T., Li, Q., Wicha, M. S. & Sun, D., Oct 1 2016, In : Biomaterials. 104, p. 145-157 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Emerging roles of ATF3 in the suppression of prostate cancer

Wang, Z. & Yan, C., Jan 2 2016, In : Molecular and Cellular Oncology. 3, 1, e1010948.

Research output: Contribution to journalArticle

14 Scopus citations
28 Scopus citations

Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells

Prusinski Fernung, L., Yang, Q., Sakamuro, D., Kumari, A., Mas, A. & Al-Hendy, A., Oct 1 2018, In : Biology of reproduction. 99, 4, p. 735-748 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-β-synthase mutant mouse

Ganapathy, P. S., Moister, B., Roon, P., Mysona, B. A., Duplantier, J., Dun, Y., Moister, T. K. V. E., Farley, M. J., Prasad, P. D., Liu, K. & Smith, S. B., 2009, In : Investigative Ophthalmology and Visual Science. 50, 9, p. 4460-4470 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Endogenous reactivation of the RARβ2 tumor suppressor gene epigenetically silenced in breast cancer

Sirchia, S. M., Ren, M., Pili, R., Sironi, E., Somenzi, G., Ghidoni, R., Toma, S., Nicolò, G. & Sacchi, N., May 1 2002, In : Cancer Research. 62, 9, p. 2455-2461 7 p.

Research output: Contribution to journalArticle

146 Scopus citations

Endothelin-1/Endothelin A receptor-mediated biased signaling is a new player in modulating human ovarian cancer cell tumorigenesis

Teoh, J. P., Park, K. M., Wang, Y., Hu, Q., Kim, S., Wu, G., Huang, S., Maihle, N. J. & Kim, I., Sep 3 2014, In : Cellular Signalling. 26, 12, p. 2885-2895 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Engineering monovalent quantum dot-antibody bioconjugates with a hybrid gel system

Liu, H. Y. & Gao, X., Mar 16 2011, In : Bioconjugate Chemistry. 22, 3, p. 510-517 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Enhanced therapeutic efficacy and memory of tumor-specific CD8 T cells by ex vivo PI3K-δ inhibition

Abu Eid, R., Ahmad, S., Lin, Y., Webb, M., Berrong, Z., Shrimali, R. K., Kumai, T., Ananth, S., Rodriguez, P. C., Celis, E., Janik, J. E., Mkrtichyan, M. & Khleif, S. N., Aug 1 2017, In : Cancer Research. 77, 15, p. 4135-4145 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Enrichment of regulatory CD4+CD25+ T cells by inhibition of phospholipase D signaling

Singh, N., Seki, Y., Takami, M., Baban, B., Chandler, P. R., Khosravi, D., Zheng, X., Takezaki, M., Lee, J. R., Mellor, A. L., Bollag, W. B. & Iwashima, M., Aug 1 2006, In : Nature Methods. 3, 8, p. 629-636 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Epidermal growth factor (EGF) and hormones stimulate phosphoinositide hydrolysis and increase EGF receptor protein synthesis and mRNA levels in rat liver epithelial cells. Evidence for protein kinase C-dependent and -independent pathways

Earp, H. S., Hepler, J. R., Petch, L. A., Miller, A., Berry, A. R., Harris, J. A., Raymond, V. W., McCune, B. K., Lee, L. W., Grisham, J. W. & Harden, T. K., 1988, In : Journal of Biological Chemistry. 263, 27, p. 13868-13874 7 p.

Research output: Contribution to journalArticle

60 Scopus citations

Epidermal growth factor expression in human colon and colon carcinomas: Anti‐sense epidermal growth factor receptor rna down‐regulates the proliferation of human colon cancer cells

Rajagopal, S., Huang, S., Moskal, T. L., Lee, BN. N., El‐Naggar, A. K. & Chakrabarty, S., Sep 15 1995, In : International Journal of Cancer. 62, 6, p. 661-667 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition

Zhang, S., Wang, X., Iqbal, S., Wang, Y., Osunkoya, A. O., Chen, Z., Chen, Z., Shin, D. M., Yuan, H., Wang, Y. A., Zhau, H. E., Chung, L. W. K., Ritenour, C., Kucuk, O. & Wu, D., Jan 18 2013, In : Journal of Biological Chemistry. 288, 3, p. 1469-1479 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Epidermal growth factor receptor-dependent stimulation of amphiregulin expression in androgen-stimulated human prostate cancer cells

Sehgal, I., Bailey, J., Hitzemann, K., Pittelkow, M. R. & Maihle, N. J., Mar 1994, In : Molecular Biology of the Cell. 5, 3, p. 339-347 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Epigenetic modulation of retinoic acid receptor β2 by the histone deacetylase inhibitor MS-275 in human renal cell carcinoma

Wang, X. F., Qian, D. Z., Ren, M., Kato, Y., Wei, Y., Zhang, L., Fansler, Z., Clark, D., Nakanishi, O. & Pili, R., May 1 2005, In : Clinical Cancer Research. 11, 9, p. 3535-3542 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

Epigenetic regulation of apoptosis and cell cycle regulatory genes in human colon carcinoma cells

Paschall, A. V. & Liu, K., Sep 1 2015, In : Genomics Data. 5, p. 189-191 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Epigenetics and colorectal cancer pathogenesis

Bardhan, K. & Liu, K., Jun 2013, In : Cancers. 5, 2, p. 676-713 38 p.

Research output: Contribution to journalArticle

134 Scopus citations

Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis

Hlady, R. A., Tiedemann, R. L., Puszyk, W., Zendejas, I., Roberts, L. R., Choi, J. H., Liu, C. & Robertson, K. D., 2014, In : Oncotarget. 5, 19, p. 9425-9443 19 p.

Research output: Contribution to journalArticle

39 Scopus citations

Epithelial-mesenchymal transition of ovarian cancer cells is sustained by Rac1 through simultaneous activation of MEK1/2 and Src signaling pathways

Fang, D., Chen, H., Zhu, J. Y., Wang, W., Teng, Y., Ding, H., Jing, Q., Su, S. B. & Huang, S., Mar 1 2017, In : Oncogene. 36, 11, p. 1546-1558 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis

Zhang, S., Wang, X., Osunkoya, A. O., Iqbal, S., Wang, Y., Chen, Z., Müller, S., Chen, Z., Josson, S., Coleman, I. M., Nelson, P. S., Wang, Y. A., Wang, R., Shin, D. M., Marshall, F. F., Kucuk, O., Chung, L. W. K., Zhau, H. E. & Wu, D., Dec 15 2011, In : Oncogene. 30, 50, p. 4941-4952 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

ESTclean: A cleaning tool for next-gen transcriptome shotgun sequencing

Tae, H., Ryu, D., Sureshchandra, S. & Choi, J-H., Sep 26 2012, In : BMC Bioinformatics. 13, 1, 247.

Research output: Contribution to journalArticle

5 Scopus citations

ESTPiper - A web-based analysis pipeline for expressed sequence tags

Tang, Z., Choi, J. H., Hemmerich, C., Sarangi, A., Colbourne, J. K. & Dong, Q., Apr 21 2009, In : BMC Genomics. 10, 174.

Research output: Contribution to journalArticle

16 Scopus citations

Evaluation of angiogenesis process after metformin and LY294002 treatment in mammary tumor

Moschetta, M. G., Leonel, C., Maschio-Signorini, L. B., Borin, T. F., Gelaleti, G. B., Jardim-Perassi, B. V., Ferreira, L. C., Sonehara, N. M., Carvalho, L. G. S., Hellmén, E. & Zuccari, D. A. P. D. C., Jan 1 2019, In : Anti-Cancer Agents in Medicinal Chemistry. 19, 5, p. 655-666 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A

Hatanaka, T., Huang, W., Ling, R., Prasad, P. D., Sugawara, M., Leibach, F. H. & Ganapathy, V., Feb 9 2001, In : Biochimica et Biophysica Acta - Biomembranes. 1510, 1-2, p. 10-17 8 p.

Research output: Contribution to journalArticle

84 Scopus citations
12 Scopus citations

Evidence that CXCL16 is a potent mediator of angiogenesis and is involved in endothelial progenitor cell chemotaxis: Studies in mice with K/BxN serum-induced arthritis

Isozaki, T., Arbab, A. S., Haas, C. S., Amin, M. A., Arendt, M. D., Koch, A. E. & Ruth, J. H., Jul 2013, In : Arthritis and Rheumatism. 65, 7, p. 1736-1746 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Evolutionary divergence of core and post-translational circadian clock genes in the pitcher-plant mosquito, Wyeomyia smithii

Tormey, D., Colbourne, J. K., Mockaitis, K., Choi, J. H., Lopez, J., Burkhart, J., Bradshaw, W. & Holzapfel, C., Oct 6 2015, In : BMC Genomics. 16, 1, 754.

Research output: Contribution to journalArticle

9 Scopus citations

Examination of the activity of carboxyl-terminal chimeric constructs of human and yeast ferrochelatases

Medlock, A. E. & Dailey, H. A., Jun 27 2000, In : Biochemistry. 39, 25, p. 7461-7467 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 σ receptor gene

Prasad, P. D., Li, H. W., Fei, Y. J., Ganapathy, M. E., Fujita, T., Plumley, L. H., Yang-Feng, T. L., Leibach, F. H. & Ganapathy, V., Feb 1998, In : Journal of Neurochemistry. 70, 2, p. 443-451 9 p.

Research output: Contribution to journalArticle

148 Scopus citations

Exosome-Derived Dystrophin from Allograft Myogenic Progenitors Improves Cardiac Function in Duchenne Muscular Dystrophic Mice

Su, X., Jin, Y., Shen, Y., Ju, C., Cai, J., Liu, Y., Kim, I., Wang, Y., Yu, H., Weintraub, N. L., Jiang, M. & Tang, Y. L., 2018, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalArticle

8 Scopus citations

Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium

Wang, Y., Zhang, L., Li, Y., Chen, L., Wang, X., Guo, W., Zhang, X., Qin, G., He, S. H., Zimmerman, A., Liu, Y., Kim, I., Weintraub, N. L. & Tang, Y. L., Jun 9 2015, In : International Journal of Cardiology. 192, p. 61-69 9 p.

Research output: Contribution to journalArticle

191 Scopus citations

Exosomes from Suxiao Jiuxin pill-treated cardiac mesenchymal stem cells decrease H3K27 demethylase UTX expression in mouse cardiomyocytes in vitro

Ruan, X. F., Li, Y. J., Ju, C. W., Shen, Y., Lei, W., Chen, C., Li, Y., Yu, H., Liu, Y., Kim, I., Wang, X. L., Weintraub, N. L. & Tang, Y. L., Apr 1 2018, In : Acta Pharmacologica Sinica. 39, 4, p. 579-586 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Experimental metastasis and CTL adoptive transfer immunotherapy mouse model

Zimmerman, M., Hu, X. & Liu, K., Nov 1 2010, In : Journal of Visualized Experiments. 45, e2077.

Research output: Contribution to journalArticle

10 Scopus citations

Expression, subcellular localization, and regulation of sigma receptor in retinal Müller cells

Jiang, G., Mysona, B., Dun, Y., Gnana-Prakasam, J. P., Pabla, N., Li, W., Dong, Z., Ganapathy, V. & Smith, S. B., Dec 2006, In : Investigative Ophthalmology and Visual Science. 47, 12, p. 5576-5582 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor α in mammalian retinal pigment epithelium

Chancy, C. D., Kekuda, R., Huang, W., Prasad, P. D., Kuhnel, J. M., Sirotnak, F. M., Roon, P., Ganapathy, V. & Smith, S. B., Jul 7 2000, In : Journal of Biological Chemistry. 275, 27, p. 20676-20684 9 p.

Research output: Contribution to journalArticle

118 Scopus citations

Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines

Gopal, E., Miyauchi, S., Martin, P. M., Ananth, S., Srinivas, S. R., Smith, S. B., Prasad, P. D. & Ganapathy, V., Jan 1 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 292, 1, p. G402-G408

Research output: Contribution to journalArticle

36 Scopus citations

Expression and function of immunoglobulin-like transcripts on tolerogenic dendritic cells

Wu, J. & Horuzsko, A., May 2009, In : Human Immunology. 70, 5, p. 353-356 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells

Umapathy, N. S., Dun, Y., Martin, P. M., Duplantier, J. N., Roon, P., Prasad, P., Smith, S. B. & Ganapathy, V., Nov 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 5151-5160 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium

Gnana-Prakasam, J. P., Ananth, S., Prasad, P. D., Zhang, M., Atherton, S. S., Martin, P. M., Smith, S. B. & Ganapathy, V., May 2011, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 3751-3758 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium

Martin, P. M., Ananth, S., Cresci, G., Roon, P., Smith, S. B. & Ganapathy, V., Feb 16 2009, In : Molecular Vision. 15, p. 362-372 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium

Martin, P. M., Gnana-Prakasam, J. P., Roon, P., Smith, R. G., Smith, S. B. & Ganapathy, V., Oct 2006, In : Investigative Ophthalmology and Visual Science. 47, 10, p. 4238-4244 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity.

Davis, M. B., Liu, X., Wang, S., Reeves, J., Khramtsov, A., Huo, D. & Olopade, O. I., 2013, In : Molecular cancer. 12, 1, 40.

Research output: Contribution to journalArticle

11 Scopus citations

Expression of a Cocaine-Sensitive Norepinephrine Transporter in the Human Placental Syncytiotrophoblast

Ramamoorthy, S., Prasad, P. D., Kulanthaivel, P., Leibach, F. H., Blakely, R. D. & Ganapathy, V., 1993, In : Biochemistry. 32, 5, p. 1346-1353 8 p.

Research output: Contribution to journalArticle

101 Scopus citations

Expression of antisense epidermal growth factor receptor RNA downmodulates the malignant behavior of human colon cancer cells

Chakrabarty, S., Rajagopal, S. & Huang, S., May 1995, In : Clinical & Experimental Metastasis. 13, 3, p. 191-195 5 p.

Research output: Contribution to journalArticle

45 Scopus citations

Expression of antisense fibronectin RNA in human colon carcinoma cells disrupts the regulation of carcinoembryonic antigen by transforming growth factor β1

Huang, S. & Chakrabarty, S., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 28764-28768 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Expression of co-stimulatory molecules on langerhans cells in lesional epidermis of human atopic dermatitis

Fesenkova, V. I., Kurchenko, A. I., Castellani, M. L., Conti, P., Anogeianaki, A., Caraffa, A. & Kalogeromitros, D., Jul 1 2007, In : Immunopharmacology and Immunotoxicology. 29, 3-4, p. 487-498 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis

Kwon, I. K., Schoenlein, P. V., Delk, J., Liu, K., Thangaraju, M., Dulin, N. O., Ganapathy, V., Berger, F. G. & Browning, D. D., Apr 1 2008, In : Cancer. 112, 7, p. 1462-1470 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Expression of peroxisome proliterator-activated receptor (PPARγ) mRNA in adipose and muscle tissue of Holstein and Charolais cattle

Huff, P. W., Ren, M. Q., Lozeman, F. J., Weselake, R. J. & Wegner, J., Mar 2004, In : Canadian Journal of Animal Science. 84, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Expression of slc5a8 in kidney and its role in Na+-coupled transport of lactate

Gopal, E., Fei, Y. J., Sugawara, M., Miyauchi, S., Zhuang, L., Martin, P., Smith, S. B., Prasad, P. D. & Ganapathy, V., Oct 22 2004, In : Journal of Biological Chemistry. 279, 43, p. 44522-44532 11 p.

Research output: Contribution to journalArticle

110 Scopus citations