Biochemistry and Molecular Biology

Research Output 1968 2020

2018
2 Citations (Scopus)

Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells

Prusinski Fernung, L., Yang, Q., Sakamuro, D., Kumari, A., Mas, A. & Al-Hendy, A., Oct 1 2018, In : Biology of reproduction. 99, 4, p. 735-748 14 p.

Research output: Contribution to journalArticle

Endocrine Disruptors
Leiomyoma
DNA Repair
Stem Cells
Incidence
4 Citations (Scopus)

Exosome-Derived Dystrophin from Allograft Myogenic Progenitors Improves Cardiac Function in Duchenne Muscular Dystrophic Mice

Su, X., Jin, Y., Shen, Y., Ju, C., Cai, J., Liu, Y., Kim, I., Wang, Y., Yu, H., Weintraub, N. L., Jiang, M. & Tang, Y. L., Jan 1 2018, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalArticle

Exosomes
Dystrophin
Allografts
Stem Cells
Duchenne Muscular Dystrophy
11 Citations (Scopus)

Exosomes from Suxiao Jiuxin pill-treated cardiac mesenchymal stem cells decrease H3K27 demethylase UTX expression in mouse cardiomyocytes in vitro

Ruan, X. F., Li, Y. J., Ju, C. W., Shen, Y., Lei, W., Chen, C., Li, Y., Yu, H., Liu, Y., Kim, I., Wang, X. L., Weintraub, N. L. & Tang, Y. L., Apr 1 2018, In : Acta Pharmacologica Sinica. 39, 4, p. 579-586 8 p.

Research output: Contribution to journalArticle

Exosomes
Mesenchymal Stromal Cells
Cardiac Myocytes
Epigenomics
Chromatin Assembly and Disassembly
4 Citations (Scopus)

FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome

Hu, T., Wu, Q., Chong, Y., Qin, H., Poole, C. J., Van Riggelen, J., Ren, M. & Cowell, J. K., Nov 1 2018, In : Leukemia. 32, 11, p. 2363-2373 11 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Phosphotransferases
Stem Cells
Granzymes
2 Citations (Scopus)

FKBP12.6 protects heart from AngII-induced hypertrophy through inhibiting Ca2+/calmodulin-mediated signalling pathways in vivo and in vitro

Xiao, Y. F., Zeng, Z. X., Guan, X. H., Wang, L. F., Wang, C. J., Shi, H., Shou, W., Deng, K. Y. & Xin, H. B., Jul 2018, In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3638-3651 14 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Calmodulin
Angiotensin II
Hypertrophy
Cardiomegaly
1 Citation (Scopus)

Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - A preliminary report

Shiao, S. P. K., Xiao, H., Dong, L., Wang, X., Liu, K., She, J. & Shi, H., May 22 2018, In : Oncotarget. 9, 39, p. 25557-25571 15 p.

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Colorectal Neoplasms
Genome
Neoplasm Genes
18 Citations (Scopus)

Giant Magnetic Heat Induction of Magnesium-Doped γ-Fe2O3 Superparamagnetic Nanoparticles for Completely Killing Tumors

Jang, J. T., Lee, J., Seon, J., Ju, E., Kim, M., Kim, Y. I., Kim, M. G., Takemura, Y., Arbab, A. S., Kang, K. W., Park, K. H., Paek, S. H. & Bae, S., Feb 8 2018, In : Advanced Materials. 30, 6, 1704362.

Research output: Contribution to journalArticle

Magnesium
Tumors
Nanoparticles
Induction heating
Oncology
2 Citations (Scopus)

Glucocorticoid-induced leucine zipper promotes neutrophil and T-cell polarization with protective effects in acute kidney injury

Baban, B., Marchetti, C., Khodadadi, H., Malik, A., Emami, G., Lin, P. C., Arbab, A. S., Riccardi, C. & Mozaffari, M. S., Dec 2018, In : Journal of Pharmacology and Experimental Therapeutics. 367, 3, p. 483-493 11 p.

Research output: Contribution to journalArticle

Leucine Zippers
Trans-Activators
Acute Kidney Injury
Glucocorticoids
Neutrophils
8 Citations (Scopus)

Glutamine via a-ketoglutarate dehydrogenase provides succinyl-CoA for heme synthesis during erythropoiesis

Burch, J. S., Marcero, J. R., Maschek, J. A., Cox, J. E., Jackson, L. K., Medlock, A. E., Phillips, J. D. & Dailey, H. A., Sep 6 2018, In : Blood. 132, 10, p. 987-998 12 p.

Research output: Contribution to journalArticle

Erythropoiesis
Glutamine
Heme
Oxidoreductases
Succinate-CoA Ligases
5 Citations (Scopus)

Gpr109a limits microbiota-induced IL-23 production to constrain ILC3-mediated colonic inflammation

Bhatt, B., Zeng, P., Zhu, H., Sivaprakasam, S., Li, S., Xiao, H., Dong, L., Shiao, S-Y. P., Kolhe, R. B., Li, H., Levy Bercowski, D., Ganapathy, V., Singh, N. & Patel, N., Apr 15 2018, In : Journal of Immunology. 200, 8, p. 2905-2914 10 p.

Research output: Contribution to journalArticle

Interleukin-23
Microbiota
Inflammation
Mycoplasmataceae
Streptococcaceae
12 Citations (Scopus)

GPR81, a cell-surface receptor for lactate, regulates intestinal homeostasis and protects mice from experimental colitis

Ranganathan, P., Shanmugam, A. K., Swafford, D., Suryawanshi, A., Bhattacharjee, P., Hussein, M. S., Koni, P., Prasad, P. D., Kurago, Z. B., Thangaraju, M., Ganapathy, V. & Manicassamy, S., Mar 1 2018, In : Journal of Immunology. 200, 5, p. 1781-1789 9 p.

Research output: Contribution to journalArticle

Cell Surface Receptors
Colitis
Lactic Acid
Homeostasis
Inflammation
1 Citation (Scopus)

Gut microbes modulate host response to immune checkpoint inhibitor cancer immunotherapy

Liu, K. & Lu, C., Jan 1 2018, In : Translational Cancer Research. 7, p. S608-S610

Research output: Contribution to journalEditorial

Immunotherapy
Neoplasms
3 Citations (Scopus)

H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells

Redd, P. S., Lu, C., Klement, J. D., Ibrahim, M. L., Zhou, G., Kumai, T., Celis, E. & Liu, K., Sep 2 2018, In : OncoImmunology. 7, 9, e1483302.

Research output: Contribution to journalArticle

T-Lymphocytes
CD8 Antigens
Immunologic Monitoring
CD4 Antigens
T-Cell Antigen Receptor
34 Citations (Scopus)

H6, a novel hederagenin derivative, reverses multidrug resistance in vitro and in vivo

Yang, Y., Guan, D., Lei, L., Lu, J., Liu, J. Q., Yang, G., Yan, C., Zhai, R., Tian, J., Bi, Y., Fu, F. & Wang, H., Feb 15 2018, In : Toxicology and Applied Pharmacology. 341, p. 98-105 8 p.

Research output: Contribution to journalArticle

Multiple Drug Resistance
P-Glycoprotein
Paclitaxel
Derivatives
Rhodamine 123

Haemophagocytic lymphohistiocytosis occurred during induction chemotherapy in an acute monocytic leukemia patient with FLT3-ITD and DNMT3A mutations

Li, F., Zhang, X., Wang, Y., Yang, A., Zhang, Z., Tang, W., Zhong, N. & Shi, H., May 29 2018, In : BMC Cancer. 18, 1, 604.

Research output: Contribution to journalArticle

Leukemia, Monocytic, Acute
Hemophagocytic Lymphohistiocytosis
Induction Chemotherapy
Mutation
Blood Component Transfusion
22 Citations (Scopus)

Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in the Murine Thromboembolic Stroke Model

Webb, R. L., Kaiser, E. E., Scoville, S. L., Thompson, T. A., Fatima, S., Pandya, C. D., Sriram, K., Swetenburg, R. L., Vaibhav, K., Arbab, A. S., Baban, B., Dhandapani, K. M., Hess, D. C., Hoda, MD. N. & Stice, S. L., Oct 1 2018, In : Translational Stroke Research. 9, 5, p. 530-539 10 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Stroke
Rodentia
Mesenchymal Stromal Cells
Extracellular Vesicles
7 Citations (Scopus)

Identification of α-fetoprotein-specific T-cell receptors for hepatocellular carcinoma immunotherapy

Zhu, W., Peng, Y., Wang, L., Hong, Y., Jiang, X., Li, Q., Liu, H., Huang, L., Wu, J., Celis, E., Merchen, T. D., Kruse, E. J. & He, Y., Aug 2018, In : Hepatology. 68, 2, p. 574-589 16 p.

Research output: Contribution to journalArticle

Fetal Proteins
T-Cell Antigen Receptor
Immunotherapy
Hepatocellular Carcinoma
T-Lymphocytes
18 Citations (Scopus)

IDO immune status after chemoradiation may predict survival in lung cancer patients

Wang, W., Huang, L., Jin, J. Y., Jolly, S., Zang, Y., Wu, H., Yan, L., Pi, W., Li, L., Mellor, A. L. & Kong, F. M., Feb 1 2018, In : Cancer Research. 78, 3, p. 809-816 8 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Lung Neoplasms
Radiotherapy
Kynurenine
Survival
7 Citations (Scopus)

IFNAR1 controls autocrine type I IFN regulation of PD-L1 expression in myeloid-derived suppressor cells

Xiao, W., Klement, J. D., Lu, C., Ibrahim, M. L. & Liu, K., Jul 1 2018, In : Journal of Immunology. 201, 1, p. 264-277 14 p.

Research output: Contribution to journalArticle

Ligands
Tumor Microenvironment
Myeloid-Derived Suppressor Cells
Neoplasms
Up-Regulation
7 Citations (Scopus)

Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression

Chaudhary, K., Promsote, W., Ananth, S., Veeranan-Karmegam, R., Tawfik, A. M., Arjunan, P., Martin, P. M., Smith, S. B., Thangaraju, M., Kisselev, O., Ganapathy, V. & Gnana-Prakasam, J. P., Dec 1 2018, In : Scientific Reports. 8, 1, 3025.

Research output: Contribution to journalArticle

Iron Overload
Diabetic Retinopathy
Renin
Iron
Knockout Mice
2 Citations (Scopus)

Kidney-targeted inhibition of protein kinase C-α ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction

Kvirkvelia, N., McMenamin, M., Warren, M., Jadeja, R. N., Kodeboyina, S. K., Sharma, A., Zhi, W., O'Connor, P. M., Raju, R., Lucas, R. & Madaio, M. P., Aug 2018, In : Kidney International. 94, 2, p. 280-291 12 p.

Research output: Contribution to journalArticle

Nephritis
Protein Kinase C
Kidney
Protein C Inhibitor
Mitochondrial Proteins
3 Citations (Scopus)

Loss of NAMPT in aging retinal pigment epithelium reduces NAD+ availability and promotes cellular senescence

Jadeja, R. N., Powell, F. L., Jones, M. A., Fuller, J., Joseph, E., Thounaojam, M. C., Bartoli, M. & Martin, P. M., Jun 1 2018, In : Aging. 10, 6, p. 1306-1323 18 p.

Research output: Contribution to journalArticle

Nicotinamide Phosphoribosyltransferase
Retinal Pigment Epithelium
Cell Aging
NAD
Retinal Diseases
6 Citations (Scopus)

Mimetics of suppressor of cytokine signaling 3: Novel potential therapeutics in triple breast cancer

La Manna, S., Lee, E., Ouzounova, M., Di Natale, C., Novellino, E., Merlino, A., Korkaya, H. & Marasco, D., Nov 1 2018, In : International Journal of Cancer. 143, 9, p. 2177-2186 10 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Breast Neoplasms
Cytokines
Neoplasms
Neoplasm Metastasis
7 Citations (Scopus)

MiR-130a and miR-145 reprogram Gr-1+CD11b+ myeloid cells and inhibit tumor metastasis through improved host immunity

Ishii, H., Vodnala, S. K., Achyut, B. R., So, J. Y., Hollander, M. C., Greten, T. F., Lal, A. & Yang, L., Dec 1 2018, In : Nature Communications. 9, 1, 2611.

Research output: Contribution to journalArticle

immunity
metastasis
Myeloid Cells
Tumors
Immunity
8 Citations (Scopus)

MiR-339 promotes development of stem cell leukemia/lymphoma syndrome via downregulation of the BCL2L11 and BAX proapoptotic genes

Hu, T., Chong, Y., Lu, S., Wang, R., Qin, H., Silva, J., Kitamura, E., Chang, C. S., Hawthorn, L. A. & Cowell, J. K., Jul 1 2018, In : Cancer Research. 78, 13, p. 3522-3531 10 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Stem Cells
Down-Regulation
Cell Survival
4 Citations (Scopus)

Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis

Ibrahim, M. L., Klement, J. D., Lu, C., Redd, P. S., Xiao, W., Yang, D., Browning, D. D., Savage, N. M., Buckhaults, P. J., Morse, H. C. & Liu, K., Dec 11 2018, In : Cell Reports. 25, 11, p. 3036-3046.e6

Research output: Contribution to journalArticle

Colitis
Interleukin-10
Colon
Carcinogenesis
Inflammation
10 Citations (Scopus)
Cardiac Myocytes
Cullin Proteins
Heart Failure
Ubiquitins
cdc Genes
3 Citations (Scopus)

Oral Pathobiont Activates Anti-Apoptotic Pathway, Promoting both Immune Suppression and Oncogenic Cell Proliferation

Arjunan, P., Meghil, M. M., Pi, W., Xu, J., Lang, L., El-Awady, A., Sullivan, W., Rajendran, M., Rabelo, M. S., Wang, T., Tawfik, O. K., Kunde-Ramamoorthy, G., Singh, N., Thangaraju, M., Susin, C., Teng, Y., Arce Munoz, R. M. & Cutler, C. W., Dec 1 2018, In : Scientific Reports. 8, 1, 16607.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Squamous Cell Carcinoma
Chronic Periodontitis
Cell Proliferation
Dendritic Cells

P38 activation induces the dissociation of tristetraprolin from Argonaute 2 to increase ARE-mRNA stabilization

Qi, M. Y., Song, J. W., Zhang, Z., Huang, S., Jing, Q. & Matera, A. G., Apr 15 2018, In : Molecular Biology of the Cell. 29, 8, p. 988-1002 15 p.

Research output: Contribution to journalArticle

Tristetraprolin
AU Rich Elements
Messenger RNA
RNA Stability
5 Citations (Scopus)

Pharmacologically targeting the myristoylation of the scaffold protein FRS2 inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression

Li, Q., Alsaidan, O. A., Ma, Y., Kim, S., Liu, J., Albers, T., Liu, K., Beharry, Z., Zhao, S., Wang, F., Lebedyeva, I. & Cai, H., Jan 1 2018, In : Journal of Biological Chemistry. 293, 17, p. 6434-6448 15 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Fibroblast Growth Factors
Fibroblast Growth Factor 2
Scaffolds
Tumors
1 Citation (Scopus)

Phosphodiesterase-5 inhibitors for colon cancer chemoprevention

Islam, B. N. & Browning, D. D., Sep 1 2018, In : Aging. 10, 9, p. 2216-2217 2 p.

Research output: Contribution to journalEditorial

Phosphodiesterase 5 Inhibitors
Chemoprevention
Colonic Neoplasms
9 Citations (Scopus)

Regenerative therapy for cardiomyopathies

Wang, Z., Su, X., Ashraf, M., Kim, I. M., Weintraub, N. L., Jiang, M. & Tang, Y., Jan 1 2018, In : Journal of Cardiovascular Translational Research. 11, 5, p. 357-365 9 p.

Research output: Contribution to journalArticle

Cardiomyopathies
Heart Diseases
Stem Cells
Cardiovascular Diseases
Exosomes

Regression analysis for secondary response variable in a case-cohort study

Pan, Y., Cai, J., Kim, S. & Zhou, H., Sep 1 2018, In : Biometrics. 74, 3, p. 1014-1022 9 p.

Research output: Contribution to journalArticle

Cohort Study
Cost effectiveness
cohort studies
Regression Analysis
Regression analysis
5 Citations (Scopus)

Remote ischemic post-conditioning promotes hematoma resolution via AMPK-dependent immune regulation

Vaibhav, K., Braun, M., Khan, M. B., Fatima, S., Saad, N., Shankar, A., Khan, Z. T., Harris, R. B. S., Yang, Q., Huo, Y., Arbab, A. S., Giri, S., Alleyne, C. H., Vender, J. R., Hess, D. C., Baban, B., Hoda, M. N. & Dhandapani, K. M., Oct 1 2018, In : The Journal of experimental medicine. 215, 10, p. 2636-2654 19 p.

Research output: Contribution to journalArticle

Ischemic Postconditioning
AMP-Activated Protein Kinases
Hematoma
Extremities
Cerebral Hemorrhage
2 Citations (Scopus)

Repositioning dopamine D2 receptor agonist bromocriptine to enhance docetaxel chemotherapy and treat bone metastatic prostate cancer

Yang, Y., Mamouni, K., Li, X., Chen, Y., Kavuri, S. K., Du, Y., Fu, H., Kucuk, O. & Wu, D., Sep 2018, In : Molecular cancer therapeutics. 17, 9, p. 1859-1870 12 p.

Research output: Contribution to journalArticle

docetaxel
Bromocriptine
Dopamine D2 Receptors
Dopamine Agonists
Prostatic Neoplasms
4 Citations (Scopus)

Rnf126 as a biomarker of a poor prognosis in invasive breast cancer and chek1 inhibitor efficacy in breast cancer cells

Yang, X., Pan, Y., Qiu, Z., Du, Z., Zhang, Y., Fa, P., Gorityala, S., Ma, S., Li, S., Chen, C., Wang, H., Xu, Y., Yan, C., Ruth, K., Ma, Z. & Zhang, J., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1629-1643 15 p.

Research output: Contribution to journalArticle

Biomarkers
Breast Neoplasms
Proteins
Staining and Labeling
Ubiquitin-Protein Ligases
5 Citations (Scopus)

Role of angiotensin system modulation on progression of cognitive impairment and brain MRI changes in aged hypertensive animals – A randomized double- blind pre-clinical study

Ahmed, H. A., Ishrat, T., Pillai, B., Bunting, K. M., Patel, A., Vazdarjanova, A., Waller, J. L., Arbab, A. S., Ergul, A. & Fagan, S. C., Jul 2 2018, In : Behavioural Brain Research. 346, p. 29-40 12 p.

Research output: Contribution to journalArticle

Angiotensins
Cognition
Magnetic Resonance Imaging
Brain
Renin-Angiotensin System
1 Citation (Scopus)

Role of MDA5 and interferon-I in dendritic cells for T cell expansion by anti-tumor peptide vaccines in mice

Sultan, H., Wu, J., Kumai, T., Salazar, A. M. & Celis, E., Jul 1 2018, In : Cancer Immunology, Immunotherapy. 67, 7, p. 1091-1103 13 p.

Research output: Contribution to journalArticle

Melanoma-Specific Antigens
Cancer Vaccines
Subunit Vaccines
Differentiation Antigens
Cytotoxic T-Lymphocytes
1 Citation (Scopus)

SALL1 expression in acute myeloid leukemia

Salman, H., Shuai, X., Nguyen-Lefebvre, A. T., Giri, B., Ren, M., Rauchman, M., Robbins, L., Hou, W., Korkaya, H. & Ma, Y., Jan 26 2018, In : Oncotarget. 9, 7, p. 7442-7452 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Acute Myeloid Leukemia
Stem Cells
Leukemia
Bone Marrow
7 Citations (Scopus)

Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization

Braun, M., Khan, Z. T., Khan, M. B., Kumar, M., Ward, A., Achyut, B. R., Arbab, A. S., Hess, D. C., Hoda, MD. N., Baban, B., Dhandapani, K. M. & Vaibhav, K., Feb 1 2018, In : Brain, Behavior, and Immunity. 68, p. 224-237 14 p.

Research output: Contribution to journalArticle

Cannabinoid Receptors
Macrophages
Endocannabinoids
Cerebrovascular Circulation
Anti-Inflammatory Agents

Sensitive liquid chromatography/tandem mass spectrometry method for the determination of two novel highly lipophilic anticancer drug candidates in rat plasma and tissues

Hooshfar, S., Linzey, M. R., Wu, D., Gera, L., Mamouni, K., Li, X., Chen, Y., Yang, Y., Olorunyolemi, O. & Bartlett, M. G., Feb 1 2018, In : Biomedical Chromatography. 32, 2, e4064.

Research output: Contribution to journalArticle

Liquid chromatography
Tandem Mass Spectrometry
Liquid Chromatography
Mass spectrometry
Rats
3 Citations (Scopus)

SRC increases MYC mRNA expression in estrogen receptor-positive breast cancer via mRNA stabilization and inhibition of p53 function

Abdullah, C., Korkaya, H., Iizuka, S. & Courtneidge, S. A., Mar 1 2018, In : Molecular and Cellular Biology. 38, 6, e00463-17.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Messenger RNA
Estrogens
RNA-Binding Proteins
3 Citations (Scopus)

Sustained persistence of il2 signaling enhances the antitumor effect of peptide vaccines through t-cell expansion and preventing pd-1 inhibition

Sultan, H., Kumai, T., Fesenkova, V. I., Fan, A. E., Wu, J., Cho, H. II., Kobayashi, H., Harabuchi, Y. & Celis, E., May 2018, In : Cancer Immunology Research. 6, 5, p. 617-627 11 p.

Research output: Contribution to journalArticle

Subunit Vaccines
Interleukin-2
T-Lymphocytes
Neoplasms
Neoplasm Antigens
7 Citations (Scopus)

Suxiao Jiuxin pill promotes exosome secretion from mouse cardiac mesenchymal stem cells in vitro

Ruan, X. F., Ju, C. W., Shen, Y., Liu, Y., Kim, I., Yu, H., Weintraub, N. L., Wang, X. L. & Tang, Y. L., Apr 1 2018, In : Acta Pharmacologica Sinica. 39, 4, p. 569-578 10 p.

Research output: Contribution to journalArticle

Exosomes
Mesenchymal Stromal Cells
Sphingomyelin Phosphodiesterase
GTP Phosphohydrolases
Therapeutics
5 Citations (Scopus)

Synergistic Targeting HER2 and EGFR with Bivalent Aptamer-siRNA Chimera Efficiently Inhibits HER2-Positive Tumor Growth

Xue, L., Maihle, N. J., Yu, X., Tang, S. C. & Liu, H., Nov 5 2018, In : Molecular Pharmaceutics. 15, 11, p. 4801-4813 13 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Breast Neoplasms
Growth
Drug Resistance
Pharmaceutical Preparations
14 Citations (Scopus)

Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer

Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In : Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Breast Neoplasms
Nucleotide Aptamers
Antibodies
Heterografts
3 Citations (Scopus)

Targeting the MYC oncogene in burkitt lymphoma through HSP90 inhibition

Poole, C. J., Zheng, W., Lee, H., Young, D., Lodh, A., Chadli, A. & van Riggelen, J., Nov 16 2018, In : Cancers. 10, 11, 448.

Research output: Contribution to journalArticle

Burkitt Lymphoma
Oncogenes
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
tanespimycin
Proteins
1 Citation (Scopus)

Tauroursodeoxycholic acid alleviates secondary injury in the spinal cord via up-regulation of CIBZ gene

Zhang, Z., Chen, J., Chen, F., Yu, D., Li, R., Lv, C., Wang, H., Li, H., Li, J. & Cai, Y., Jul 1 2018, In : Cell Stress and Chaperones. 23, 4, p. 551-560 10 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Up-Regulation
Genes
Endoplasmic Reticulum Stress
Apoptosis
3 Citations (Scopus)
STAT1 Transcription Factor
effectors
ischemia
kidneys
Reperfusion Injury
8 Citations (Scopus)

The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer

Kadi, N. E., Wang, L., Davis, A., Korkaya, H., Cooke, A., Vadnala, V., Brown, N. A., Betz, B. L., Cascalho, M., Kalemkerian, G. P. & Hassan, K. A., Dec 15 2018, In : Cancer Research. 78, 24, p. 6728-6735 8 p.

Research output: Contribution to journalArticle

5-Methylcytosine
Deamination
Protein-Tyrosine Kinases
Lung Neoplasms
Mutation