Biochemistry and Molecular Biology

Research Output 1968 2019

Filter
Article
1968
273 Citations (Scopus)

The biology of isolated chromatin

Bonner, J., Dahmus, M. E., Fambrough, D., Huang, R. C. C., Marushige, K. & Tuan Lo, D., Jan 1 1968, In : Science. 159, 3810, p. 47-56 10 p.

Research output: Contribution to journalArticle

Chromatin
Chromosomes
Genes
1969
99 Citations (Scopus)

Optical absorbance and optical rotatory dispersion studies on calf thymus nucleohistone

Tuan Lo, D. & Bonner, J., Oct 14 1969, In : Journal of Molecular Biology. 45, 1, p. 59-76 18 p.

Research output: Contribution to journalArticle

Optical Rotatory Dispersion
Histones
Thymus Gland
DNA
Osmolar Concentration
1973
49 Citations (Scopus)

Isolation of the Nonhistone Proteins of Rat Walker Carcinoma 256. Their Association with Tumor Angiogenesis

Tuan Lo, D., Smith, S., Folkman, J. & Merler, E., Aug 1 1973, In : Biochemistry. 12, 17, p. 3159-3165 7 p.

Research output: Contribution to journalArticle

Walker Carcinoma 256
Rats
Tumors
Histones
Guanidine
1975
30 Citations (Scopus)

Aconitase polymorphism in man

SLAUGHTER, C. A., HOPKINSON, D. A. & HARRIS, HARRY., Oct 1975, In : Annals of Human Genetics. 39, 2, p. 193-202 10 p.

Research output: Contribution to journalArticle

Aconitate Hydratase
Isoenzymes
Alleles
Population
Phenotype
1976
1 Citation (Scopus)

Adenylate kinase and aconitase in human rodent somatic cell hybrids

Povey, S., Slaughter, C. A., Wilson, D. E., Buckton, K., Gormley, I. P. & Perry, P., Dec 1 1976, In : Cytogenetics and Cell Genetics. 16, 1-5, p. 211-214 4 p.

Research output: Contribution to journalArticle

Chromosomes, Human, 6-12 and X
Aconitate Hydratase
Hydro-Lyases
Adenylate Kinase
Hybrid Cells
1 Citation (Scopus)

Adenylate kinase and aconitase in human rodent somatic cell hybrids HUMAN GENE MAPPING.3.

Povey, S., Slaughter, C. A., Wilson, D. E., Buckton, K., Gormley, I. P. & Perry, P., Dec 1 1976, In : Birth Defects: Original Article Series. 12, 7, p. 211-214 4 p.

Research output: Contribution to journalArticle

Chromosomes, Human, 6-12 and X
Aconitate Hydratase
Hydro-Lyases
Adenylate Kinase
Hybrid Cells
52 Citations (Scopus)

Evidence for the assignment of the loci AK1, AK3 and ACONs to chromosome 9 in man

POVEY, S., Slaughter, C. A., WILSON, D. E., GORMLEY, I. P., BUCKTON, K. E., PERRY, P. & BOBROW, M., Jan 1 1976, In : Annals of Human Genetics. 39, 4, p. 413-422 10 p.

Research output: Contribution to journalArticle

Aconitate Hydratase
Adenylate Kinase
Chromosomes, Human, Pair 9
nucleoside triphosphate-adenylate kinase
Nail-Patella Syndrome
1977
40 Citations (Scopus)

Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells

Prasad, P. D., Ramamoorthy, S., Leibach, F. H. & Ganapathy, V., Sep 1 1977, In : Placenta. 18, 7, p. 527-533 7 p.

Research output: Contribution to journalArticle

Choriocarcinoma
Biotin
Vitamins
Sodium
Valinomycin
8 Citations (Scopus)

Sequence specific interaction of the chromosomal proteins with DNA

Tuan Lo, D., Chetsanga, C. & Doty, P. M., Oct 1 1977, In : Nucleic Acids Research. 4, 10, p. 3415-3439 25 p.

Research output: Contribution to journalArticle

Chromatin
DNA
Nucleic Acid Repetitive Sequences
Proteins
Histones
1978
9 Citations (Scopus)

Assignment of the locus ACONM to chromosome 22

Slaughter, C. A., Povey, S., Carritt, B., Solomon, E. & Bobrow, M., Jan 1 1978, In : Cytogenetic and Genome Research. 22, 1-6, p. 223-225 3 p.

Research output: Contribution to journalArticle

Minor Lymphocyte Stimulatory Loci
Chromosomes, Human, Pair 22
Aconitate Hydratase
Chromosomes, Human, Pair 9
Rodentia
1979
66 Citations (Scopus)

Restriction endonuclease mapping of the human γ globin gene loci

Tuan Lo, D., Biro, P. A., Deriel, J. K., Lazarus, H. & Forget, B. G., Jun 11 1979, In : Nucleic Acids Research. 6, 7, p. 2519-2544 26 p.

Research output: Contribution to journalArticle

Restriction Mapping
Globins
Genes
DNA
Fetal Hemoglobin
1980

ANALYSIS OF β‐GLOBIN GENES IN β^ THALASSEMIA

Tuan Lo, D., Biro, P. A., De Riel, J. K. & Forget, B. G., Jan 1 1980, In : Annals of the New York Academy of Sciences. 344, 1, p. 12-30 19 p.

Research output: Contribution to journalArticle

Genetic Suppression
Nucleic Acid Hybridization
Chromosome Deletion
Thalassemia
Globins
20 Citations (Scopus)

Cotransfer of circular and linear prokaryotic and eukaryotic DNA sequences into mouse cells.

Hsiung, N., Warrick, H., deRiel, J. K., Tuan Lo, D., Forget, B. G., Skoultchi, A. & Kucherlapati, R., Jan 1 1980, In : Proceedings of the National Academy of Sciences of the United States of America. 77, 8, p. 4852-4856 5 p.

Research output: Contribution to journalArticle

Thymidine Kinase
Plasmids
Genes
beta-Globins
Transfection
42 Citations (Scopus)

Heterogeneity in the molecular basis of hereditary persistence of fetal haemoglobin

Tuan Lo, D., Murnane, M. J., DeRiel, J. K. & Forget, B. G., Dec 1 1980, In : Nature. 285, 5763, p. 335-337 3 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Globins
Gene Deletion
DNA
Hemoglobins
13 Citations (Scopus)

Morphological and ultrastructural features of Nikitinsporites canadensis chaloner, a devonian megaspore from the frasnian of canada

Taylor, T. N., Maihle, N. J. & Hills, L. V., Jan 1 1980, In : Review of Palaeobotany and Palynology. 30, C, p. 89-99 11 p.

Research output: Contribution to journalArticle

megaspores
Frasnian
ornamentation
ultrastructure
appendages
1981
56 Citations (Scopus)

Calmodulin localization during capping and receptor-mediated endocytosis

Salisbury, J. L., Condeelis, J. S., Maihle, N. J. & Satir, P., Dec 1 1981, In : Nature. 294, 5837, p. 163-166 4 p.

Research output: Contribution to journalArticle

Receptor Aggregation
Calmodulin
Endocytosis
Trifluoperazine
Ligands
15 Citations (Scopus)
Electrophoresis
Monoclonal Antibodies
Enzymes
Gels
Alleles
13 Citations (Scopus)

Ultrastructure of the flagellar apparatus of the green alga Tetraselmis subcordiformis - With special consideration given to the function of the rhizoplast and rhizanchora

Salisbury, J. L., Swanson, J. A., Floyd, G. L., Hall, R. & Maihle, N. J., Mar 1 1981, In : Protoplasma. 107, 1-2, p. 1-11 11 p.

Research output: Contribution to journalArticle

Basal Bodies
Tetraselmis
Chlorophyta
microtubules
ultrastructure
1982
64 Citations (Scopus)

A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin

Jagadeeswaran, P., Tuan Lo, D., Forget, B. G. & Weissman, S. M., Dec 1 1982, In : Nature. 296, 5856, p. 469-470 2 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Nucleic Acid Repetitive Sequences
Gene Deletion
Globins
Genes
1983
34 Citations (Scopus)
Amino Acid Sequence
Antibodies
p-Azobenzenearsonate
Hybridomas
Radioimmunoassay
82 Citations (Scopus)

cDNA cloning of the bovine low density lipoprotein receptor: Feedback regulation of a receptor mRNA

Russell, D. W., Yamamoto, T., Schneider, W. J., Slaughter, C. A., Brown, M. S. & Goldstein, J. L., Jan 1 1983, In : Proceedings of the National Academy of Sciences of the United States of America. 80, 24 I, p. 7501-7505 5 p.

Research output: Contribution to journalArticle

LDL Receptors
Organism Cloning
Complementary DNA
Messenger RNA
Cyanogen Bromide
13 Citations (Scopus)

Discrimination of human placental alkaline phosphatase allelic variants by monoclonal antibodies

Slaughter, C. A., Gogolin, K. J., Coseo, M. C., Meyer, L. J., Lesko, J. & Harris, H., Apr 14 1983, In : American journal of human genetics. 35, 1, p. 1-20 20 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Antibodies
Phenotype
placental alkaline phosphatase
Hybridomas
3 Citations (Scopus)

Molecular studies of mutations that increase Hb F production in man.

Forget, B. G., Tuan Lo, D., Newman, M. V., Feingold, E. A., Collins, F., Fukumaki, Y., Jagadeeswaran, P. & Weissman, S. M., Dec 1 1983, In : Progress in clinical and biological research. 134, p. 65-76 12 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Chromosome Deletion
Thalassemia
Chromosome Mapping
Gene Expression Regulation
20 Citations (Scopus)

Neoisostegane, a new bisbenzocyclooctadiene lignan lactone from Steganotaenia araliacea hochst.

Hicks, R. P. & Sneden, A. T., Jan 1 1983, In : Tetrahedron Letters. 24, 29, p. 2987-2990 4 p.

Research output: Contribution to journalArticle

Araliaceae
Lignans
Lactones
Nuclear magnetic resonance
Proton Magnetic Resonance Spectroscopy
1984
79 Citations (Scopus)
Globins
K562 Cells
Deoxyribonuclease I
Leukemia
myc Genes
15 Citations (Scopus)

Neoisostegane, A New Bisbenzocyclooctadiene Lignan Lactone from Steganotaenia Araliacea1

Taafrout, M., Rouessac, F., Robin, J. P., Hicks, R. P., Shillady, D. D. & Sneden, A. T., Jan 1 1984, In : Journal of Natural Products. 47, 4, p. 600-606 7 p.

Research output: Contribution to journalArticle

Lignans
Lactones
Araliaceae
Isomerization
Functional groups
1985

Agonist-induced change in the membrane form of muscarinic cholinergic receptors (MR) in astrocytoma cells

Harden, T. K., Petch Lee, L. A. & Traynelis, S. F., Jan 1 1985, In : Federation Proceedings. 44, 5

Research output: Contribution to journalArticle

Astrocytoma
Cholinergic Receptors
Muscarinic Receptors
Membranes
7 Citations (Scopus)

Preparation of glucosidic derivatives of steganol

Hicks, R. P. & Sneden, A. T., Jan 1 1985, In : Journal of Natural Products. 48, 3, p. 357-362 6 p.

Research output: Contribution to journalArticle

Glucosides
Derivatives
Podophyllotoxin
Acetaldehyde
Assays
410 Citations (Scopus)

The 'β-like-globin' gene domain in human erythroid cells

Tuan Lo, D., Solomon, W., Li, Q. & London, I. M., Jan 1 1985, In : Proceedings of the National Academy of Sciences of the United States of America. 82, 19, p. 6384-6388 5 p.

Research output: Contribution to journalArticle

Erythroid Cells
Globins
Deoxyribonuclease I
Genes
DNA
1986
3 Citations (Scopus)

Blood utilization for elective general surgery at the Port-of-Spain General Hospital.

Monteil, M. A. & Naraynsingh, V., Dec 1 1986, In : West Indian Medical Journal. 35, 4, p. 293-294 2 p.

Research output: Contribution to journalArticle

Hospital Surgery Department
Blood Grouping and Crossmatching
Trinidad and Tobago
Blood Banks
Hospital Departments
341 Citations (Scopus)

Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase

Weiss, M. J., Henthorn, P. S., Lafferty, M. A., Slaughter, C. A., Raducha, M. & Harris, H., Dec 19 1986, In : Proceedings of the National Academy of Sciences of the United States of America. 83, 19, p. 7182-7186 5 p.

Research output: Contribution to journalArticle

Alkaline Phosphatase
Complementary DNA
Liver
Kidney
Bone and Bones
61 Citations (Scopus)

Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids

Henthorn, P. S., Knoll, B. J., Raducha, M., Rothblum, K. N., Slaughter, C. A., Weiss, M., Lafferty, M. A., Fischer, T. & Harris, H., Dec 19 1986, In : Proceedings of the National Academy of Sciences of the United States of America. 83, 15, p. 5597-5601 5 p.

Research output: Contribution to journalArticle

Amino Acid Sequence
Complementary DNA
Alleles
Amino Acids
Gene Library
1987
56 Citations (Scopus)

Application of a protein-blotting procedure to the study of human glucocorticoid receptor interactions with DNA

Silva, C. M., Tully, D. B., Petch, L. A., Jewell, C. M. & Cidlowski, J. A., Jun 11 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 7, p. 1744-1748 5 p.

Research output: Contribution to journalArticle

Glucocorticoid Receptors
Mouse mammary tumor virus
DNA
Proteins
Collodion
112 Citations (Scopus)

Nucleotide and amino acid sequences of human intestinal alkaline phosphatase: Close homology to placental alkaline phosphatase

Henthorn, P. S., Raducha, M., Edwards, Y. H., Weiss, M. J., Slaughter, C. A., Lafferty, M. A. & Harris, H., Apr 29 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 5, p. 1234-1238 5 p.

Research output: Contribution to journalArticle

Amino Acid Sequence
Nucleotides
Alkaline Phosphatase
Amino Acids
Complementary DNA
1988
16 Citations (Scopus)

Analysis of phenylthiohydantoin amino acid mixtures for sequencing by thermospray liquid chromatography/mass spectrometry

Pramanik, B. C., Hinton, S. M., Millington, D. S., Dourdeville, T. A. & Slaughter, C. A., Nov 15 1988, In : Analytical Biochemistry. 175, 1, p. 305-318 14 p.

Research output: Contribution to journalArticle

Phenylthiohydantoin
Liquid chromatography
Protein Sequence Analysis
Liquid Chromatography
Mass spectrometry
60 Citations (Scopus)

Epidermal growth factor (EGF) and hormones stimulate phosphoinositide hydrolysis and increase EGF receptor protein synthesis and mRNA levels in rat liver epithelial cells. Evidence for protein kinase C-dependent and -independent pathways

Earp, H. S., Hepler, J. R., Petch Lee, L. A., Miller, A., Berry, A. R., Harris, J. A., Raymond, V. W., McCune, B. K., Lee, L. W., Grisham, J. W. & Harden, T. K., Jan 1 1988, In : Journal of Biological Chemistry. 263, 27, p. 13868-13874 7 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Epidermal Growth Factor Receptor
Epidermal Growth Factor
Liver
Protein Kinase C
84 Citations (Scopus)

Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins

Sudhof, T. C., Slaughter, C. A., leznicki, I., Barjon, P. & Reynolds, G. A., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 3, p. 664-668 5 p.

Research output: Contribution to journalArticle

Annexin A6
Annexins
Proteins
Phospholipids
Annexin A2
135 Citations (Scopus)

Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Gil, G., Smith, J. R., Goldstein, J. L., Slaughter, C. A., Orth, K., Brown, M. S. & Osborn, T. F., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 23, p. 8963-8967 5 p.

Research output: Contribution to journalArticle

NFI Transcription Factors
Oxidoreductases
Genes
Proteins
Cricetinae
1989
197 Citations (Scopus)

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human 'β-like globin' genes

Tuan Lo, D., Solomon, W. B., London, I. M. & Lee, D. P., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 8, p. 2554-2558 5 p.

Research output: Contribution to journalArticle

Globins
Genes
Erythroid Cells
Genetic Complementation Test
118 Citations (Scopus)

cDNA cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper

Dawson, P. A., Ridgway, N. D., Slaughter, C. A., Brown, M. S. & Goldstein, J. L., Jan 1 1989, In : Journal of Biological Chemistry. 264, 28, p. 16798-16803 6 p.

Research output: Contribution to journalArticle

Leucine Zippers
Cloning
Oligomers
Organism Cloning
Complementary DNA
16 Citations (Scopus)

Disease tropism of c-erbB: Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation

Pelley, R. J., Maihle, N. J., Boerkoel, C., Shu, H. K., Carter, T. H., Moscovici, C. & Kung, H. J., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 18, p. 7164-7168 5 p.

Research output: Contribution to journalArticle

Tropism
Tyrosine
Phosphotransferases
Avian Leukosis Virus
Leukemia, Erythroblastic, Acute
9 Citations (Scopus)

One hundred years of retinoblastoma Research: From the clinic to the gene and back again

Cowell, J. K., Jun 1 1989, In : Ophthalmic Paediatrics and Genetics. 10, 2, p. 75-88 14 p.

Research output: Contribution to journalArticle

Retinoblastoma
Research
Genes
Neoplasms
Chromosomes, Human, Pair 13
1990
151 Citations (Scopus)

Association of protein phosphatase 2A with polyoma virus medium tumor antigen

Walter, G., Ruediger, R., Slaughter, C. A. & Mumby, M., Jan 1 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 7, p. 2521-2525 5 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Polyomavirus
Neoplasm Antigens
Proteins
Simian virus 40
171 Citations (Scopus)

A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue

Petch Lee, L. A., Harris, J., Raymond, V. W., Blasband, A., Lee, D. C. & Earp, H. S., Jan 1 1990, In : Molecular and Cellular Biology. 10, 6, p. 2973-2982 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Messenger RNA
Clone Cells
Epidermal Growth Factor
Hepatocytes
4 Citations (Scopus)

NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays

Kaplita, P. V., Abreu, M. E., Connor, J. R., Erickson, R. H., Ferkany, J. W., Hicks, R. P., Schenden, J. A., Noronha‐Blob, L. & Hanson, R. C., Jan 1 1990, In : Drug Development Research. 20, 4, p. 429-443 15 p.

Research output: Contribution to journalArticle

Adenosine A1 Receptor Antagonists
Xanthine
Guinea Pigs
Adenylyl Cyclases
Adenosine A2 Receptors

Retroviral insertional mutagenesis: the making of a receptor-oncogene.

Kung, H. J., Pelley, R. J., Shu, H. K., Maihle, N. J., Raines, M., Carter, T., Boerkoel, C., Moscovici, G. & Moscovici, C., Jan 1 1990, In : Developments in biological standardization. 72, p. 139-144 6 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Avian Leukosis Virus
Leukemia, Erythroblastic, Acute
Insertional Mutagenesis
Viral DNA
8 Citations (Scopus)

Staphylococcal opsonization and anti-Staphylococcus aureus IgG subclass antibodies in patients with severe or recurrent S. aureus infections

Monteil, M. A., Kaniuk, A. S. C. & Hobbs, J. R., Dec 1990, In : FEMS Microbiology Letters. 64, 5-6, p. 259-262 4 p.

Research output: Contribution to journalArticle

Staphylococcus aureus
Immunoglobulin G
Antibodies
Infection
Staphylococcal Infections
73 Citations (Scopus)

The fruitfly Drosophila melanogaster contains a novel charged adipokinetic-hormone-family peptide

Schaffer, M. H., Noyes, B. E., Slaughter, C. A., Thorne, G. C. & Gaskell, S. J., Jan 1 1990, In : Biochemical Journal. 269, 2, p. 315-320 6 p.

Research output: Contribution to journalArticle

Drosophila melanogaster
Peptides
Pyrrolidonecarboxylic Acid
Arthropods
Neuropeptides
1991
46 Citations (Scopus)

1,3,8-Trisubstituted Xanthines. Effects of Substitution Pattern upon Adenosine Receptor A1/A2 Affinity

Erickson, R. H., Hiner, R. N., Feeney, S. W., Blake, P. R., Rzeszotarski, W. J., Hicks, R. P., Costello, D. G. & Abreu, M. E., Apr 1 1991, In : Journal of Medicinal Chemistry. 34, 4, p. 1431-1435 5 p.

Research output: Contribution to journalArticle

Xanthines
Adenosine A2 Receptors
Adenosine A1 Receptors
varespladib methyl
44 Citations (Scopus)

A conserved sequence element in ribonuclease III processing signals is not required for accurate in vitro enzymatic cleavage

Chelladurai, B. S., Li, H. & Nicholson, A. W., Apr 25 1991, In : Nucleic Acids Research. 19, 8, p. 1759-1766 8 p.

Research output: Contribution to journalArticle

Ribonuclease III
Conserved Sequence
RNA
Base Pairing
RNA Phages