Biochemistry and Molecular Biology

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2009

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

Fiskus, W., Wang, Y., Sreekumar, A., Buckley, K. M., Shi, H., Jillella, A., Ustun, C., Rao, R., Fernandez, P., Chen, J., Balusu, R., Koul, S., Atadja, P., Marquez, V. E. & Bhalla, K. N., 2009, In : Blood. 114, 13, p. 2733-2743 11 p.

Research output: Contribution to journalArticle

269 Scopus citations

Derangement of a factor upstream of RARalpha triggers the repression of a pleiotropic epigenetic network.

Corlazzoli, F., Rossetti, S., Bistulfi, G., Ren, M. & Sacchi, N., 2009, In : PloS one. 4, 1, p. e4305

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma

Bennett, L. B., Schnabel, J. L., Kelchen, J. M., Taylor, K. H., Guo, J., Arthur, G. L., Papageorgio, C. N., Shi, H. & Caldwell, C. W., Sep 2009, In : Genes Chromosomes and Cancer. 48, 9, p. 828-841 14 p.

Research output: Contribution to journalArticle

52 Scopus citations

Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-β-synthase mutant mouse

Ganapathy, P. S., Moister, B., Roon, P., Mysona, B. A., Duplantier, J., Dun, Y., Moister, T. K. V. E., Farley, M. J., Prasad, P. D., Liu, K. & Smith, S. B., 2009, In : Investigative Ophthalmology and Visual Science. 50, 9, p. 4460-4470 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

ESTPiper - A web-based analysis pipeline for expressed sequence tags

Tang, Z., Choi, J. H., Hemmerich, C., Sarangi, A., Colbourne, J. K. & Dong, Q., Apr 21 2009, In : BMC Genomics. 10, 174.

Research output: Contribution to journalArticle

16 Scopus citations

Expression and function of immunoglobulin-like transcripts on tolerogenic dendritic cells

Wu, J. & Horuzsko, A., May 2009, In : Human Immunology. 70, 5, p. 353-356 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium

Martin, P. M., Ananth, S., Cresci, G., Roon, P., Smith, S. B. & Ganapathy, V., Feb 16 2009, In : Molecular Vision. 15, p. 362-372 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection

Gnana-Prakasam, J. P., Zhang, M., Martin, P. M., Atherton, S. S., Smith, S. B. & Ganapathy, V., May 1 2009, In : Biochemical Journal. 419, 3, p. 533-543 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression

Chen, H., Zhu, G., Li, Y., Padia, R. N., Dong, Z., Pan, Z. K., Liu, K. & Huang, S., Dec 15 2009, In : Cancer Research. 69, 24, p. 9228-9235 8 p.

Research output: Contribution to journalArticle

131 Scopus citations

Foxp3-deficient regulatory T cells do not revert into conventional effector CD4+ T cells but constitute a unique cell subset

Kuczma, M., Podolsky, R., Garge, N., Daniely, D., Pacholczyk, R., Ignatowicz, L. & Kraj, P., Sep 15 2009, In : Journal of Immunology. 183, 6, p. 3731-3741 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Functional Identification of a Novel Transport System for Endogenous and Synthetic Opioid Peptides in the Rabbit Conjunctival Epithelial Cell Line CJVE

Ananth, S., Karunakaran, S., Martin, P. M., Nagineni, C. N., Hooks, J. J., Smith, S. B., Prasad, P. D. & Ganapathy, V., May 2009, In : Pharmaceutical Research. 26, 5, p. 1226-1235 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
34 Scopus citations

Genotypic and functional roles of IL-1B and IL-1RN on the risk of gastroesophageal reflux disease: the presence of IL-1B-511*T/IL-1RN*1 (T1) haplotype may protect against the disease

Chourasia, D., Achyut, B. R., Tripathi, S., Mittal, B., Mittal, R. D. & Ghoshal, U. C., Nov 2009, In : American Journal of Gastroenterology. 104, 11, p. 2704-13 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three

ISAAC Phase Three Study Group, Dec 1 2009, In : Journal of Allergy and Clinical Immunology. 124, 6

Research output: Contribution to journalArticle

432 Scopus citations

GPFM 09A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon

Thangaraju, M., Cresci, G. A., Liu, K., Ananth, S., Gnanaprakasam, J. P., Browning, D. D., Mellinger, J. D., Smith, S. B., Digby, G. J., Lambert, N. A., Prasad, P. D. & Ganapathy, V., Apr 1 2009, In : Cancer Research. 69, 7, p. 2826-2832 7 p.

Research output: Contribution to journalArticle

263 Scopus citations

High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

Jones, H. N., Woollett, L. A., Barbour, N., Prasad, P. D., Powell, T. L. & Jansson, T., Jan 2009, In : FASEB Journal. 23, 1, p. 271-278 8 p.

Research output: Contribution to journalArticle

204 Scopus citations

IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression

Yang, D., Wang, S., Brooks, C., Dong, Z., Schoenlein, P. V., Kumar, V., Ouyang, X., Xiong, H., Lahat, G., Hayes-Jordan, A., Lazar, A., Pollock, R., Lev, D. & Liu, K., Feb 1 2009, In : Cancer Research. 69, 3, p. 1080-1088 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Important roles of the conserved linker-KKS in human neuronal growth inhibitory factor

Ding, Z-C., Teng, X. C., Zheng, Q., Ni, F. Y., Cai, B., Wang, Y., Zhou, G. M., Sun, H. Z., Tan, X. S. & Huang, Z. X., Oct 1 2009, In : BioMetals. 22, 5, p. 817-826 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Induction of CRP3/MLP expression during vein arterialization is dependent on stretch rather than shear stress

Campos, L. C. G., Miyakawa, A. A., Barauna, V. G., Cardoso, L., Borin, T. F., Dallan, L. A. D. O. & Krieger, J. E., Jul 2009, In : Cardiovascular Research. 83, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Interferon regulatory factor-8 modulates the development of tumour-induced CD11b +Gr-1 + myeloid cells

Stewart, T. J., Greeneltch, K. M., Reid, J. E., Liewehr, D. J., Steinberg, S. M., Liu, K. & Abrams, S. I., Sep 2009, In : Journal of Cellular and Molecular Medicine. 13, 9 B, p. 3939-3950 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Isoforms of human leukocyte antigen-G and their inhibitory receptors in human kidney allograft acceptance

Wu, J., Zhang, W., Hernandez-Lopez, P., Fabelo, E., Parikh, M., Mulloy, L. L. & Horuzsko, A., Dec 1 2009, In : Human Immunology. 70, 12, p. 988-994 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Lipopolysaccharide-driven Th2 cytokine production in macrophages is regulated by both MyD88 and TRAM

Mukherjee, S., Chen, L. Y., Papadimos, T. J., Huang, S., Zuraw, B. L. & Pan, Z. K., Oct 23 2009, In : Journal of Biological Chemistry. 284, 43, p. 29391-29398 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Microarray comparison of prostate tumor gene expression in African-American and Caucasian American males: A pilot project study

Reams, R. R., Agrawal, D., Davis, M. B., Yoder, S., Odedina, F. T., Kumar, N., Higginbotham, J. M., Akinremi, T., Suther, S. & Soliman, K. F. A., 2009, In : Infectious Agents and Cancer. 4, SUPPL. 1, S3.

Research output: Contribution to journalArticle

40 Scopus citations

Modular, easy-to-assemble, low-cost zebrafish facility

Kim, S., Carlson, R., Zafreen, L., Rajpurohit, S. K. & Jagadeeswaran, P., Sep 2009, In : Zebrafish. 6, 3, p. 269-74 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
9 Scopus citations

Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration

Su, S., Li, Y., Luo, Y., Sheng, Y., Su, Y., Padia, R. N., Pan, Z. K., Dong, Z. & Huang, S., Aug 27 2009, In : Oncogene. 28, 34, p. 3047-3057 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Quantum dot hybrid gel blotting: a technique for identifying quantum dot-protein/protein-protein interactions.

Vu, T. Q. & Liu, H., Jan 1 2009, In : Methods in molecular biology (Clifton, N.J.). 544, p. 381-391 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Regulation of placental amino acid transporter activity by mammalian target of rapamycin

Roos, S., Kanai, Y., Prasad, P. D., Powell, T. L. & Jansson, T., Jan 2009, In : American Journal of Physiology - Cell Physiology. 296, 1, p. C142-C150

Research output: Contribution to journalArticle

97 Scopus citations

Single particle quantum dot imaging achieves ultrasensitive detection capabilities for Western immunoblot analysis

Scholl, B., Liu, H. Y., Long, B. R., McCarty, O. J. T., O'Hare, T., Druker, B. J. & Vu, T. Q., Jun 23 2009, In : ACS Nano. 3, 6, p. 1318-1328 11 p.

Research output: Contribution to journalArticle

20 Scopus citations
12 Scopus citations

Synergistic induction of inflammation by bacterial products lipopolysaccharide and fMLP: An important microbial pathogenic mechanism

Chen, L. Y., Pan, W. W., Chen, M., Li, J. D., Liu, W., Chen, G., Huang, S., Papadimos, T. J. & Pan, Z. K., Feb 15 2009, In : Journal of Immunology. 182, 4, p. 2518-2524 7 p.

Research output: Contribution to journalArticle

17 Scopus citations
143 Scopus citations

The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice

Carlson, B. A., Schweizer, U., Perella, C., Shrimali, R. K., Feigenbaum, L., Shen, L., Speransky, S., Floss, T., Jeong, S. J., Watts, J., Hoffmann, V., Combs, G. F., Gladyshev, V. N. & Hatfield, D. L., Feb 15 2009, In : Biochemical Journal. 418, 1, p. 61-71 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

The structural and biological significance of the EAAEAE insert in the α-domain of human neuronal growth inhibitory factor

Cai, B., Ding, Z-C., Zhang, Q., Ni, F. Y., Wang, H., Zheng, Q., Wang, Y., Zhou, G. M., Wang, K. Q., Sun, H. Z., Wu, H. M. & Huang, Z. X., Jul 2009, In : FEBS Journal. 276, 13, p. 3547-3558 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Tie2cre-induced inactivation of the miRNA-processing enzyme Dicer disrupts invariant NKT cell development

Zhou, L., Seo, K. H., He, H. Z., Pacholczyk, R. W., Meng, D. M., Li, C. G., Xu, J., She, J-X., Dong, Z. & Mi, Q. S., Jun 23 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 25, p. 10266-10271 6 p.

Research output: Contribution to journalArticle

76 Scopus citations

Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate

Thangaraju, M., Karunakaran, S. K., Itagaki, S., Gopal, E., Elangovan, S., Prasad, P. D. & Ganapathy, V., Oct 15 2009, In : Cancer. 115, 20, p. 4655-4666 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Trastuzumab-lnduced HER reprogramming in "Resistant" breast carcinoma cells

Narayan, M., Wilken, J. A., Harris, L. N., Baron, A. T., Kimbler, K. D. & Maihle, N. J., Mar 15 2009, In : Cancer Research. 69, 6, p. 2191-2194 4 p.

Research output: Contribution to journalArticle

150 Scopus citations
2010

A garter snake transcriptome: Pyrosequencing, de novo assembly, and sex-specific differences

Schwartz, T. S., Tae, H., Yang, Y., Mockaitis, K., Van Hemert, J. L., Proulx, S. R., Choi, J. H. & Bronikowski, A. M., Dec 7 2010, In : BMC Genomics. 11, 1, 694.

Research output: Contribution to journalArticle

53 Scopus citations

A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing protein 1 (DDRGK1) and modulates NF-κB signaling

Wu, J., Lei, G., Mei, M., Tang, Y. & Li, H., May 14 2010, In : Journal of Biological Chemistry. 285, 20, p. 15126-15136 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

Shrimali, R. K., Yu, Z., Theoret, M. R., Chinnasamy, D., Restifo, N. P. & Rosenberg, S. A., Aug 1 2010, In : Cancer Research. 70, 15, p. 6171-6180 10 p.

Research output: Contribution to journalArticle

353 Scopus citations

Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells

Sukumari-Ramesh, S., Laird, M. D., Singh, N., Vender, J. R., Alleyne, C. H. & Dhandapani, K. M., Nov 15 2010, In : Glia. 58, 15, p. 1858-1870 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury

Jiang, M., Liu, K., Luo, J. & Dong, Z., Mar 2010, In : American Journal of Pathology. 176, 3, p. 1181-1192 12 p.

Research output: Contribution to journalArticle

272 Scopus citations
105 Scopus citations

CD4+CD25+ regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis

Singh, N., Yamamoto, M., Takami, M., Seki, Y., Takezaki, M., Mellor, A. L. & Iwashima, M., Jan 1 2010, In : Journal of Immunology. 184, 1, p. 94-104 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Characteristics of the genome of Arsenophonus nasoniae, son-killer bacterium of the wasp Nasonia

Darby, A. C., Choi, J. H., Wilkes, T., Hughes, M. A., Werren, J. H., Hurst, G. D. D. & Colbourne, J. K., Feb 2010, In : Insect Molecular Biology. 19, SUPPL. 1, p. 75-89 15 p.

Research output: Contribution to journalArticle

44 Scopus citations

Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype

Ding, Z. C., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Mar 25 2010, In : Blood. 115, 12, p. 2397-2406 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Cleavage of the retinal pigment epithelium-specific protein RPE65 under oxidative stress

Lee, H., Chung, H., Arnouk, H., Powell, F. L., Hunt, R. C., Hrushesky, W. J. M., Wood, P. A., Lee, S. H. & Jahng, W. J., Aug 2010, In : International Journal of Biological Macromolecules. 47, 2, p. 104-108 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8

Cresci, G. A., Thangaraju, M., Mellinger, J. D., Liu, K. & Ganapathy, V., Mar 1 2010, In : Journal of Gastrointestinal Surgery. 14, 3, p. 449-461 13 p.

Research output: Contribution to journalArticle

85 Scopus citations

Defective T-cell receptor-induced apoptosis of T cells and rejection of transplanted immunogenic tumors in p53-/- mice

Singh, N., Huang, L. & Qin, H., Feb 2010, In : European Journal of Immunology. 40, 2, p. 559-568 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: A RPE specific phenomenon

Ananth, S., Zhuang, L., Gopal, E., Itagaki, S., Ellappan, B., Smith, S. B., Ganapathy, V. & Martin, P., Mar 26 2010, In : Biochemical and Biophysical Research Communications. 394, 1, p. 75-80 6 p.

Research output: Contribution to journalArticle

9 Scopus citations