Biochemistry and Molecular Biology

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2004

Ectopic expression of nonliganded retinoic acid receptor β abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells

Arce, J. D. C., Soto, U., Van Riggelen, J., Schwarz, E., Zur Hausen, H. & Rösl, F., Oct 29 2004, In : Journal of Biological Chemistry. 279, 44, p. 45408-45416 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effect of high fat diet on body weight and mammary tumor latency in MMTV-TGF-α mice

Cleary, M. P., Grande, J. P. & Maihle, N. J., Aug 1 2004, In : International Journal of Obesity. 28, 8, p. 956-962 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Expression of peroxisome proliterator-activated receptor (PPARγ) mRNA in adipose and muscle tissue of Holstein and Charolais cattle

Huff, P. W., Ren, M. Q., Lozeman, F. J., Weselake, R. J. & Wegner, J., Mar 2004, In : Canadian Journal of Animal Science. 84, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Expression of slc5a8 in kidney and its role in Na+-coupled transport of lactate

Gopal, E., Fei, Y. J., Sugawara, M., Miyauchi, S., Zhuang, L., Martin, P., Smith, S. B., Prasad, P. D. & Ganapathy, V., Oct 22 2004, In : Journal of Biological Chemistry. 279, 43, p. 44522-44532 11 p.

Research output: Contribution to journalArticle

110 Scopus citations

Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development

Kalinichenko, V. V., Gusarova, G. A., Kim, I., Shin, B., Yoder, H. M., Clark, J., Sapozhnikov, A. M., Whitsett, J. A. & Costa, R. H., Mar 2004, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 286, 3 30-3, p. L521-L530

Research output: Contribution to journalArticle

52 Scopus citations

Growth performance, carcass characteristics and bioavailability of isoflavones in pigs fed soy bean based diets

Kuhn, G., Hennig, U., Kalbe, C., Rehfeldt, C., Ren, M. Q., Moors, S. & Degen, G. H., Aug 1 2004, In : Archives of Animal Nutrition. 58, 4, p. 265-276 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

HS2 enhancer function is blocked by a transcriptional terminator inserted between the enhancer and the promoter

Ling, J., Ainol, L., Zhang, L., Yu, X., Pi, W. & Tuan Lo, D., Dec 3 2004, In : Journal of Biological Chemistry. 279, 49, p. 51704-51713 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Identification and characterization of the major Huperzine A metabolite in rat blood

Garcia, G. E., Hicks, R. P., Skanchy, D., Moorad-Doctor, D. R., Doctor, B. P. & Ved, H. S., Jan 1 2004, In : Journal of Analytical Toxicology. 28, 5, p. 379-383 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Leptin Receptor-Deficient MMTV-TGF-α/LeprdbLepr db Female Mice Do Not Develop Oncogene-Induced Mammary Tumors

Cleary, M. P., Juneja, S. C., Phillips, F. C., Hu, X., Grande, J. P. & Maihle, N. J., Feb 2004, In : Experimental Biology and Medicine. 229, 2, p. 182-193 12 p.

Research output: Contribution to journalArticle

114 Scopus citations

Lysophosphatidic acid stimulates ovarian cancer cell migration via a Ras-MEK kinase 1 pathway

Bian, D., Su, S., Mahanivong, C., Cheng, R. K., Han, Q., Pan, Z. K., Sun, P. & Huang, S., Jun 15 2004, In : Cancer Research. 64, 12, p. 4209-4217 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling

Satyanarayana, A., Greenberg, R. A., Schaetzlein, S., Buer, J., Masutomi, K., Hahn, W. C., Zimmermann, S., Martens, U., Manns, M. P. & Rudolph, K. L., Jun 2004, In : Molecular and Cellular Biology. 24, 12, p. 5459-5474 16 p.

Research output: Contribution to journalArticle

58 Scopus citations

Nuclear magnetic resonance and molecular modeling analysis of the interaction of the antimalarial drugs artelinic acid and artesunic acid with β-cyclodextrin

Hartell, M. G., Hicks, R., Bhattacharjee, A. K., Koser, B. W., Carvalho, K. & Van Hamont, J. E., Jan 1 2004, In : Journal of Pharmaceutical Sciences. 93, 8, p. 2076-2089 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Osmoregulation of Taurine Transporter Function and Expression in Retinal Pigment Epithelial, Ganglion, and Müller Cells

El-Sherbeny, A., Naggar, H., Miyauchi, S., Ola, M. S., Maddox, D. M., Martin, P. M., Ganapathy, V. & Smith, S. B., Feb 2004, In : Investigative Ophthalmology and Visual Science. 45, 2, p. 694-701 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

P38 mitogen-activated protein kinase regulation of endothelial cell migration depends on urokinase plasminogen activator expression

Yu, J., Bian, D., Mahanivong, C., Cheng, R. K., Zhou, W. & Huang, S., Nov 26 2004, In : Journal of Biological Chemistry. 279, 48, p. 50446-50454 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Pfg-nmr investigations of the binding of cationic neuropeptides to anionic and zwitterionic micelles

Whitehead, T. L., Jones, L. M. & Hicks, R. P., Feb 2004, In : Journal of Biomolecular Structure and Dynamics. 21, 4, p. 567-576 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Protease inhibitor and nonnucleoside reverse transcriptase inhibitor concentrations in the genital tract of HIV-1-infected women

Min, S. S., Corbett, A. H., Rezk, N., Cu-Uvin, S., Fiscus, S. A., Petch, L., Cohen, M. S. & Kashuba, A. D. M., Dec 15 2004, In : Journal of Acquired Immune Deficiency Syndromes. 37, 5, p. 1577-1580 4 p.

Research output: Contribution to journalArticle

44 Scopus citations

Recent advances in Drosophila genomics

Davis, M. B. & White, K. P., 2004, In : Genome Biology. 5, 8, 339.

Research output: Contribution to journalArticle

3 Scopus citations

Sasa Health exerts a protective effect on Her2/NeuN mammary tumorigenesis

Ren, M., Reilly, R. T. & Sacchi, N., Sep 1 2004, In : Anticancer research. 24, 5 A, p. 2879-2884 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Serine racemase and D-serine transport in human placenta and evidence for a transplacental gradient for D-serine in humans

Chen, Z., Huang, W., Srinivas, S. R., Jones, C. R., Ganapathy, V. & Prasad, P. D., Jul 1 2004, In : Journal of the Society for Gynecologic Investigation. 11, 5, p. 294-303 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Smoking at home is strongly associated with symptoms of asthma and rhinitis in children of primary school age in Trinidad and Tobago

Monteil, M. A., Joseph, G., Kit, C. C., Wheeler, G. & Antoine, R. M., Sep 2004, In : Revista Panamericana de Salud Publica/Pan American Journal of Public Health. 16, 3, p. 193-198 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Sperm membrane protein profiles of fertile and infertile men: Identification and characterization of fertility-associated sperm antigen

Rajeev, S. K. & Reddy, K. V. R., Feb 2004, In : Human Reproduction. 19, 2, p. 234-242 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Structure-activity relationship study of antimalarial indolo [2,1-b]quinazoline-6,12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of new antimalarial candidates

Bhattacharjee, A. K., Hartell, M. G., Nichols, D. A., Hicks, R. P., Stanton, B., Van Hamont, J. E. & Milhous, W. K., Jan 2004, In : European Journal of Medicinal Chemistry. 39, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

100 Scopus citations

The anthrax protective antigen (PA63) bound conformation of a peptide inhibitor of the binding of lethal factor to PA63: As determined by trNOESY NMR and molecular modeling

Hicks, R. P., Bhattacharjee, A. K., Koser, B. W. & Traficante, D. D., Oct 21 2004, In : Journal of Medicinal Chemistry. 47, 22, p. 5347-5355 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

The association of dimethylsulfoxide and model membranes studied by pulse-field gradient NMR

Kennedy, A., Long, C. J., Hmel, P. J., Hicks, R. & Reid, T. J., 2004, In : Spectroscopy. 18, 2, p. 265-269 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

The hepatitis E virus open reading frame 3 protein activates ERK through binding and inhibition of the MAPK phosphatase

Kar-Roy, A., Korkaya, H., Oberoi, R., Lal, S. K. & Jameel, S., Jul 2 2004, In : Journal of Biological Chemistry. 279, 27, p. 28345-28357 13 p.

Research output: Contribution to journalArticle

63 Scopus citations

The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans

Pi, W., Yang, Z., Wang, J., Ruan, L., Yu, X., Ling, J., Krantz, S., Isales, C. M., Conway, S. J., Lin, S. & Tuan Lo, D., Jan 20 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 3, p. 805-810 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate

Martin, P. M., Ola, M. S., Agarwal, N., Ganapathy, V. & Smith, S. B., Apr 7 2004, In : Molecular Brain Research. 123, 1-2, p. 66-75 10 p.

Research output: Contribution to journalArticle

63 Scopus citations

Transporter-Mediated Effects of Diclofenamic Acid and Its Ascorbyl Pro-drug in the In Vivo Neurotropic Activity of Ascorbyl Nipecotic Acid Conjugate

Dalpiaz, A., Pavan, B., Scaglianti, M., Vitali, F., Bortolotti, F., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Prasad, P. & Manfredini, S., Jan 2004, In : Journal of Pharmaceutical Sciences. 93, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
2005

Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination

Yan, C., Lu, D., Hai, T. & Boyd, D. D., Jul 6 2005, In : EMBO Journal. 24, 13, p. 2425-2435 11 p.

Research output: Contribution to journalArticle

141 Scopus citations

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., Feb 2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

African dust clouds are associated with increased paediatric asthma accident and emergency admissions on the Caribbean island of Trinidad

Gyan, K., Henry, W., Lacaille, S., Laloo, A., Lamsee-Ebanks, C., McKay, S., Antoine, R. M. & Monteil, M. A., Jul 1 2005, In : International Journal of Biometeorology. 49, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

113 Scopus citations

A novel protein kinase C (PKCε) is required for fMet-Leu-Phe-induced activation of NF-κB in human peripheral blood monocytes

Chen, L. Y., Doerner, A., Lehmann, P. F., Huang, S., Zhong, G. & Pan, Z. K., Jun 10 2005, In : Journal of Biological Chemistry. 280, 23, p. 22497-22501 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Ascorbic and 6-Br-ascorbic acid conjugates as a tool to increase the therapeutic effects of potentially central active drugs

Dalpiaz, A., Pavan, B., Vertuani, S., Vitali, F., Scaglianti, M., Bortolotti, F., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Marzola, G., Prasad, P. & Manfredini, S., Mar 2005, In : European Journal of Pharmaceutical Sciences. 24, 4, p. 259-269 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Biological functions of SLC5A8, a candidate tumour suppressor

Ganapathy, V., Gopal, E., Miyauchi, S. & Prasad, P. O., Feb 1 2005, In : Biochemical Society Transactions. 33, 1, p. 237-240 4 p.

Research output: Contribution to journalArticle

73 Scopus citations

C/EBPδ is a crucial regulator of pro-apoptotic gene expression during mammary gland involution

Thangaraju, M., Rudelius, M., Bierie, B., Raffeld, M., Sharan, S., Hennighausen, L., Huang, A. M. & Sterneck, E., Nov 2005, In : Development. 132, 21, p. 4675-4685 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2)

Srinivas, S. R., Gopal, E., Zhuang, L., Itagaki, S., Martin, P. M., Fei, Y. J., Ganapathy, V. & Prasad, P. D., Dec 15 2005, In : Biochemical Journal. 392, 3, p. 655-664 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Comparison of prevalence and severity of asthma among adolescents in the Caribbean islands of Trinidad and Tobago: Results of a nationwide cross-sectional survey

Monteil, M. A., Joseph, G., Changkit, C., Wheeler, G. & Antoine, R. M., Sep 14 2005, In : BMC public health. 5, 96.

Research output: Contribution to journalArticle

17 Scopus citations

Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis

Liu, H. Y., Zheng, G., Treber, M., Dai, J. & Woldegiorgis, G., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 4524-4531 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Epigenetic modulation of retinoic acid receptor β2 by the histone deacetylase inhibitor MS-275 in human renal cell carcinoma

Wang, X. F., Qian, D. Z., Ren, M., Kato, Y., Wei, Y., Zhang, L., Fansler, Z., Clark, D., Nakanishi, O. & Pili, R., May 1 2005, In : Clinical Cancer Research. 11, 9, p. 3535-3542 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

Genotypic analysis of the protease and reverse transcriptase of HIV type 1 subtype C isolates from antiretroviral drug-naive adults in Malawi

Petch, L. A., Hoffman, I. F., Jere, C. S., Kazembe, P. N., Martinson, F. E., Chilongozi, D., Fiscus, S. A. & Cohen, M. S., Sep 1 2005, In : AIDS Research and Human Retroviruses. 21, 9, p. 799-805 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Impaired retinoic acid (RA) signal leads to RARβ2 epigenetic silencing and RA resistance

Ren, M. Q., Pozzi, S., Bistulfi, G., Somenzi, G., Rossetti, S. & Sacchi, N., Dec 2005, In : Molecular and Cellular Biology. 25, 23, p. 10591-10603 13 p.

Research output: Contribution to journalArticle

50 Scopus citations

Inhibition of amino acid transport system A by interleukin-1β in trophoblasts

Thongsong, B., Subramanian, R. K., Ganapathy, V. & Prasad, P. D., Oct 1 2005, In : Journal of the Society for Gynecologic Investigation. 12, 7, p. 495-503 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

In vivo imaging of retinoic acid receptor β2 transcriptional activation by the histone deacetylase inhibitor MS-275 in retinoid-resistant prostate cancer cells

Qian, D. Z., Ren, M., Wei, Y., Wang, X., Van De Geijn, F., Rasmussen, C., Nakanishi, O., Sacchi, N. & Pili, R., Jun 15 2005, In : Prostate. 64, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Involvement of MicroRNA in AU-Rich Element-Mediated mRNA Instability

Jing, Q., Huang, S., Guth, S., Zarubin, T., Motoyama, A., Chen, J., Di Padova, F., Lin, S. C., Gram, H. & Han, J., Mar 11 2005, In : Cell. 120, 5, p. 623-634 12 p.

Research output: Contribution to journalArticle

654 Scopus citations

Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells

Van Riggelen, J., Buchwalter, G., Soto, U., De-Castro Arce, J., Zur Hausen, H., Wasylyk, B. & Rösl, F., Feb 4 2005, In : Journal of Biological Chemistry. 280, 5, p. 3286-3294 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Phenotypic analysis of EcR-A mutants suggests that EcR isoforms have unique functions during Drosophila development

Davis, M. B., Carney, G. E., Robertson, A. E. & Bender, M., Jun 15 2005, In : Developmental Biology. 282, 2, p. 385-396 12 p.

Research output: Contribution to journalArticle

74 Scopus citations

Selenocysteine tRNA identification in the model organisms Dictyostelium discoideum and Tetrahymena thermophila

Shrimali, R. K., Lobanov, A. V., Xu, X. M., Rao, M., Carlson, B. A., Mahadeo, D. C., Parent, C. A., Gladyshev, V. N. & Hatfield, D. L., Apr 1 2005, In : Biochemical and Biophysical Research Communications. 329, 1, p. 147-151 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells

Li, H., Ye, X., Mahanivong, C., Bian, D., Chun, J. & Huang, S., Mar 18 2005, In : Journal of Biological Chemistry. 280, 11, p. 10564-10571 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family

Gopal, E., Fei, Y. J., Miyauchi, S., Zhuang, L., Prasad, P. D. & Ganapathy, V., May 15 2005, In : Biochemical Journal. 388, 1, p. 309-316 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Soluble epidermal growth factor receptor (SEG-FR) and cancer antigen 125 (CA125) as screening and diagnostic tests for epithelial ovarian cancer

Baron, A. T., Boardman, C. H., Lafky, J. M., Rademaker, A., Liu, D., Fishman, D. A., Podratz, K. C. & Maihle, N. J., Feb 2005, In : Cancer Epidemiology Biomarkers and Prevention. 14, 2, p. 306-318 13 p.

Research output: Contribution to journalArticle

51 Scopus citations