Biochemistry and Molecular Biology

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2005

Studies on epidermal growth factor receptor signaling in vertebrate limb patterning

Omi, M., Fisher, M., Maihle, N. J. & Dealy, C. N., Jun 1 2005, In : Developmental Dynamics. 233, 2, p. 288-300 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo

Lechel, A., Satyanarayana, A., Ju, Z., Plentz, R. R., Schaetzlein, S., Rudolph, C., Wilkens, L., Wiemann, S. U., Saretzki, G., Malek, N. P., Manns, M. P., Buer, J. & Rudolph, K. L., Mar 2005, In : EMBO Reports. 6, 3, p. 275-281 7 p.

Research output: Contribution to journalArticle

68 Scopus citations

The HS2 enhancer of the β-globin locus control region initiates synthesis of non-coding, polyadenylated RNAs independent of a cis-linked globin promoter

Ling, J., Baibakov, B., Pi, W., Emerson, B. M. & Tuan, D., Jul 29 2005, In : Journal of Molecular Biology. 350, 5, p. 883-896 14 p.

Research output: Contribution to journalArticle

44 Scopus citations

The long terminal repeat (LTR) of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2

Yu, X., Zhu, X., Pi, W., Ling, J., Ko, L., Takeda, Y. & Tuan, D., Oct 21 2005, In : Journal of Biological Chemistry. 280, 42, p. 35184-35194 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Tolerization of dendritic cells by HLA-G

Ristich, V., Liang, S., Zhang, W., Wu, J. & Horuzsko, A., Apr 1 2005, In : European Journal of Immunology. 35, 4, p. 1133-1142 10 p.

Research output: Contribution to journalArticle

240 Scopus citations

Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans

Gupta, N., Miyauchi, S., Martindale, R. G., Herdman, A. V., Podolsky, R., Miyake, K., Mager, S., Prasad, P. D., Ganapathy, M. E. & Ganapathy, V., Jun 30 2005, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1741, 1-2, p. 215-223 9 p.

Research output: Contribution to journalArticle

67 Scopus citations
2006

A2A adenosine receptor protects tumors from antitumor T cells

Ohta, A., Gorelik, E., Prasad, S. J., Ronchese, F., Lukashev, D., Wong, M. K. K., Huang, X., Caldwell, S., Liu, K., Smith, P., Chen, J. F., Jackson, E. K., Apasov, S., Abrams, S. & Sitkovsky, M., Aug 29 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 35, p. 13132-13137 6 p.

Research output: Contribution to journalArticle

476 Scopus citations

An anti-tumor role for cGMP-dependent protein kinase

Hou, Y., Gupta, N., Schoenlein, P., Wong, E., Martindale, R., Ganapathy, V. & Browning, D., Aug 18 2006, In : Cancer Letters. 240, 1, p. 60-68 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

A repressive epigenetic domino effect confers susceptibility to breast epithelial cell transformation: Implications for predicting breast cancer risk

Bistulfi, G., Pozzi, S., Ren, M. Q., Rossetti, S. & Sacchi, N., Nov 1 2006, In : Cancer Research. 66, 21, p. 10308-10314 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

A role for cyclic-GMP dependent protein kinase in anoikis

Hou, Y., Wong, E., Martin, J., Schoenlein, P. V., Dostmann, W. R. & Browning, D. D., Jun 1 2006, In : Cellular Signalling. 18, 6, p. 882-888 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

A simplified cloning strategy for the generation of an endothelial cell selective recombinant adenovirus vector

Mahanivong, C., Krüger, J. A., Bian, D., Reisfeld, R. A. & Huang, S., Jul 1 2006, In : Journal of Virological Methods. 135, 1, p. 127-135 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Blood lead levels in primary school children in Trinidad and Tobago

Rajkumar, W. S., Manohar, J., Doon, R., Siung-Chang, A., Chang-Yen, I. & Monteil, M., May 15 2006, In : Science of the Total Environment. 361, 1-3, p. 81-87 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

c/ebpδ null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney

Thangaraju, M., Ananth, S., Martin, P. M., Roon, P., Smith, S. B., Sterneck, E., Prasad, P. D. & Ganapathy, V., Sep 15 2006, In : Journal of Biological Chemistry. 281, 37, p. 26769-26773 5 p.

Research output: Contribution to journalArticle

56 Scopus citations

Circadian clocks regulate adenylyl cyclase activity rhythms in human RPE cells

Pavan, B., Frigato, E., Pozzati, S., Prasad, P. D., Bertolucci, C. & Biondi, C., Nov 10 2006, In : Biochemical and Biophysical Research Communications. 350, 1, p. 169-173 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer

Pejovic, T., Yates, J. E., Liu, H. Y., Hays, L. E., Akkari, Y., Torimaru, Y., Keeble, W., Rathbun, R. K., Rodgers, W. H., Bale, A. E., Ameziane, N., Zwaan, C. M., Errami, A., Thuillier, P., Cappuccini, F., Olson, S. B., Cain, J. M. & Bagby, G. C., Sep 15 2006, In : Cancer Research. 66, 18, p. 9017-9025 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Down-regulation of BCRP/ABCG2 in colorectal and cervical cancer

Gupta, N., Martin, P. M., Miyauchi, S., Ananth, S., Herdman, A. V., Martindale, R. G., Podolsky, R. & Ganapathy, V., May 5 2006, In : Biochemical and Biophysical Research Communications. 343, 2, p. 571-577 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Enrichment of regulatory CD4+CD25+ T cells by inhibition of phospholipase D signaling

Singh, N., Seki, Y., Takami, M., Baban, B., Chandler, P. R., Khosravi, D., Zheng, X., Takezaki, M., Lee, J. R., Mellor, A. L., Bollag, W. B. & Iwashima, M., Aug 1 2006, In : Nature Methods. 3, 8, p. 629-636 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Expression, subcellular localization, and regulation of sigma receptor in retinal Müller cells

Jiang, G., Mysona, B., Dun, Y., Gnana-Prakasam, J. P., Pabla, N., Li, W., Dong, Z., Ganapathy, V. & Smith, S. B., Dec 2006, In : Investigative Ophthalmology and Visual Science. 47, 12, p. 5576-5582 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium

Martin, P. M., Gnana-Prakasam, J. P., Roon, P., Smith, R. G., Smith, S. B. & Ganapathy, V., Oct 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 10, p. 4238-4244 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Functional Characteristics of NaS2, a Placenta-specific Na+-coupled Transporter for Sulfate and Oxyanions of the Micronutrients Selenium and Chromium

Miyauchi, S., Srinivas, S. R., Fei, Y. J., Gopal, E., Umapathy, N. S., Wang, H., Conway, S. J., Ganapathy, V. & Prasad, P. D., Jun 1 2006, In : Placenta. 27, 6-7, p. 550-559 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Heterologous expression systems for studying placental transporters.

Ganapathy, V., Fei, Y. J. & Prasad, P. D., Jan 1 2006, In : Methods in molecular medicine. 122, p. 285-300 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

Human papillomavirus E7 oncoprotein dysregulates steroid receptor coactivator 1 localization and function

Baldwin, A., Huh, K. W. & Münger, K., Jul 2006, In : Journal of Virology. 80, 13, p. 6669-6677 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of L-lactate and ketone bodies in the brain

Martin, P. M., Gopal, E., Ananth, S., Zhuang, L., Itagaki, S., Prasad, B. M., Smith, S. B., Prasad, P. D. & Ganapathy, V., Jul 1 2006, In : Journal of Neurochemistry. 98, 1, p. 279-288 10 p.

Research output: Contribution to journalArticle

91 Scopus citations

Inhibition of sperm-egg binding and fertilisation in mice by a monoclonal antibody reactive to 57-kDa human sperm surface antigen

Reddy, K. V. R., Vijayalaxmi, G., Rajeev, K. S. & Aranha, C., Nov 29 2006, In : Reproduction, Fertility and Development. 18, 8, p. 875-884 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8)

Itagaki, S., Gopal, E., Zhuang, L., Fei, Y. J., Miyauchi, S., Prasad, P. D. & Ganapathy, V., Jun 1 2006, In : Pharmaceutical Research. 23, 6, p. 1209-1216 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Lck couples Shc to TCR signaling

Fukushima, A., Hatanaka, Y., Chang, J. W., Takamatsu, M., Singh, N. & Iwashima, M., Aug 1 2006, In : Cellular Signalling. 18, 8, p. 1182-1189 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Mutation at Glu23 eliminates the neuron growth inhibitory activity of human metallothionein-3

Ding, Z-C., Teng, X. C., Cai, B., Wang, H., Zheng, Q., Wang, Y., Zhou, G. M., Zhang, M. J., Wu, H. M., Sun, H. Z. & Huang, Z. X., Oct 20 2006, In : Biochemical and Biophysical Research Communications. 349, 2, p. 674-682 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Origin and T Cell Receptor Diversity of Foxp3+CD4+CD25+ T Cells

Pacholczyk, R., Ignatowicz, H., Kraj, P. & Ignatowicz, L., Aug 1 2006, In : Immunity. 25, 2, p. 249-259 11 p.

Research output: Contribution to journalArticle

230 Scopus citations

Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase

Taurin, S., Sandbo, N., Qin, Y., Browning, D. & Dulin, N. O., Apr 14 2006, In : Journal of Biological Chemistry. 281, 15, p. 9971-9976 6 p.

Research output: Contribution to journalArticle

294 Scopus citations

Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation

Xu, Y., Huang, S., Liu, Z. G. & Han, J., Mar 31 2006, In : Journal of Biological Chemistry. 281, 13, p. 8788-8795 8 p.

Research output: Contribution to journalArticle

194 Scopus citations

Prevalence and antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus isolates from Trinidad & Tobago

Akpaka, P. E., Kissoon, S., Swanston, W. H. & Monteil, M., Jul 3 2006, In : Annals of Clinical Microbiology and Antimicrobials. 5, 16.

Research output: Contribution to journalArticle

22 Scopus citations

SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases

Thangaraju, M., Gopal, E., Martin, P. M., Ananth, S., Smith, S. B., Prasad, P. D., Sterneck, E. & Ganapathy, V., Dec 15 2006, In : Cancer Research. 66, 24, p. 11560-11564 5 p.

Research output: Contribution to journalArticle

96 Scopus citations

Soluble epidermal growth factor receptor acridinium-linked immunosorbent assay.

Lafky, J. M., Baron, A. T. & Maihle, N. J., Jan 1 2006, In : Methods in molecular biology (Clifton, N.J.). 327, p. 39-47 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Stromal-epithelial interaction in prostate cancer progression

Chung, L. W. K., Huang, W. C., Sung, S. Y., Wu, D., Odero-Marah, V., Nomura, T., Shigemura, K., Miyagi, T., Seo, S., Shi, C., Molitierno, J., Elmore, J., Anderson, C., Isotani, S., Edlund, M., Hsieh, C. L., Wang, R., Shehata, B. & Zhau, H. E., Jan 1 2006, In : Clinical Genitourinary Cancer. 5, 2, p. 162-170 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch

Giuriato, S., Ryeom, S., Fan, A. C., Bachireddy, P., Lynch, R. C., Rioth, M. J., Van Riggelen, J., Kopelman, A. M., Passegué, E., Tang, F., Folkman, J. & Felsher, D. W., Oct 31 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 44, p. 16266-16271 6 p.

Research output: Contribution to journalArticle

110 Scopus citations

The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration

Bian, D., Mahanivong, C., Yu, J., Frisch, S. M., Pan, Z. K., Ye, R. D. & Huang, S., Apr 6 2006, In : Oncogene. 25, 15, p. 2234-2244 11 p.

Research output: Contribution to journalArticle

86 Scopus citations

The Granulin-Epithelin Precursor Is a Steroid-Regulated Growth Factor in Endometrial Cancer

Jones, M. B., Houwink, A. P., Freeman, B. K., Greenwood, T. M., Lafky, J. M., Lingle, W. L., Berchuck, A., Maxwell, G. L., Podratz, K. C. & Maihle, N. J., May 2006, In : Journal of the Society for Gynecologic Investigation. 13, 4, p. 304-311 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis

Pondarré, C., Antiochos, B. B., Campagna, D. R., Clarke, S. L., Greer, E. L., Deck, K. M., McDonald, A., Han, A. P., Medlock, A., Kutok, J. L., Anderson, S. A., Eisenstein, R. S. & Fleming, M. D., Mar 1 2006, In : Human Molecular Genetics. 15, 6, p. 953-964 12 p.

Research output: Contribution to journalArticle

152 Scopus citations

The role of mast cells and eosinophils in chronic gastritis

Moorchung, N., Srivastava, A. N., Gupta, N. K., Malaviya, A. K., Achyut, B. R. & Mittal, B., Oct 2006, In : Clinical and Experimental Medicine. 6, 3, p. 107-14 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Up-regulation of the amino acid transporter ATB0,+ (SLC6A14) in carcinoma of the cervix

Gupta, N., Prasad, P. D., Ghamande, S., Moore-Martin, P., Herdman, A. V., Martindale, R. G., Podolsky, R., Mager, S., Ganapathy, M. E. & Ganapathy, V., Jan 1 2006, In : Gynecologic Oncology. 100, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

β2-microglobulin is a signaling and growth-promoting factor for human prostate cancer bone metastasis

Huang, W. C., Wu, D., Xie, Z., Zhau, H. E., Nomura, T., Zayzafoon, M., Pohl, J., Hsieh, C. L., Weitzmann, M. N., Farach-Carson, M. C. & Chung, L. W. K., Sep 15 2006, In : Cancer Research. 66, 18, p. 9108-9116 9 p.

Research output: Contribution to journalArticle

80 Scopus citations

β2-microglobulin promotes the growth of human renal cell carcinoma through the activation of the protein kinase A, cyclic AMP-responsive element-binding protein, and vascular endothelial growth factor axis

Nomura, T., Huang, W. C., Zhau, H. E., Wu, D., Xie, Z., Mimata, H., Zayzafoon, M., Young, A. N., Marshall, F. F., Weitzmann, M. N. & Chung, L. W. K., Dec 15 2006, In : Clinical Cancer Research. 12, 24, p. 7294-7305 12 p.

Research output: Contribution to journalArticle

56 Scopus citations
2007

A facilitated tracking and transcription mechanism of long-range enhancer function

Zhu, X., Ling, J., Zhang, L., Pi, W., Wu, M. & Tuan Lo, D., Aug 2007, In : Nucleic Acids Research. 35, 16, p. 5532-5544 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis

Dailey, H. A., Wu, C. K., Horanyi, P., Medlock, A. E., Najahi-Missaoui, W., Burden, A. E., Dailey, T. A. & Rose, J., Jul 10 2007, In : Biochemistry. 46, 27, p. 7973-7979 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Apoptosis in the skeletal muscle of untreated children with juvenile dermatomyositis: Impact of duration of untreated disease

Zhao, Y., Fedczyna, T. O., McVicker, V., Caliendo, J., Li, H. & Pachman, L. M., Nov 2007, In : Clinical Immunology. 125, 2, p. 165-172 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Application of 3D-QSAR for identification of descriptors defining bioactivity of antimicrobial peptides

Bhonsle, J. B., Venugopal, D., Huddler, D. P., Magill, A. J. & Hicks, R. P., Dec 27 2007, In : Journal of Medicinal Chemistry. 50, 26, p. 6545-6553 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

A π-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase

Medlock, A. E., Dailey, T. A., Ross, T. A., Dailey, H. A. & Lanzilotta, W. N., Nov 2 2007, In : Journal of Molecular Biology. 373, 4, p. 1006-1016 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Baseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic response to combination therapy in children (PACTG 338)

Fiscus, S. A., Kovacs, A., Petch, L. A., Hu, C., Wiznia, A. A., Mofenson, L. M., Yogev, R., McIntosh, K., Pelton, S. I., Napravnik, S., Stanley, K. & Nachman, S. A., 2007, In : AIDS Research and Therapy. 4, 2.

Research output: Contribution to journalArticle

3 Scopus citations

Brief hyperglycaemia in the early pregnant rat increases fetal weight at term by stimulating placental growth and affecting placental nutrient transport

Ericsson, A., Säljö, K., Sjöstrand, E., Jansson, N., Prasad, P. D., Powell, T. L. & Jansson, T., Jun 1 2007, In : Journal of Physiology. 581, 3, p. 1323-1332 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

cAMP-responsive element-binding protein regulates vascular endothelial growth factor expression: Implication in human prostate cancer bone metastasis

Wu, D., Zhau, H. E., Huang, W. C., Iqbal, S., Habib, F. K., Sartor, O., Cvitanovic, L., Marshall, F. F., Xu, Z. & Chung, L. W. K., Aug 2 2007, In : Oncogene. 26, 35, p. 5070-5077 8 p.

Research output: Contribution to journalArticle

98 Scopus citations