Biochemistry and Molecular Biology

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2016

Oncogenic microRNA-4534 regulates PTEN pathway in prostate cancer

Nip, H., Dar, A. A., Saini, S., Colden, M., Varahram, S., Chowdhary, H., Yamamura, S., Mitsui, Y., Tanaka, Y., Kato, T., Hashimoto, Y., Shiina, M., Kulkarni, P., Dasgupta, P., Imai-Sumida, M., Laura Tabatabai, Z., Greene, K., Deng, G., Dahiya, R. & Majid, S., 2016, In : Oncotarget. 7, 42, p. 68371-68384 14 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease

Promsote, W., Powell, F. L., Veean, S., Thounaojam, M., Markand, S., Saul, A., Gutsaeva, D., Bartoli, M., Smith, S. B., Ganapathy, V. & Martin, P. M., Dec 10 2016, In : Antioxidants and Redox Signaling. 25, 17, p. 921-935 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction

Livingston, M. J., Ding, H. F., Huang, S., Hill, J. A., Yin, X. M. & Dong, Z., Jun 2 2016, In : Autophagy. 12, 6, p. 976-998 23 p.

Research output: Contribution to journalArticle

76 Scopus citations

Phenotypic alteration of CD8+ T cells in chronic lymphocytic leukemia is associated with epigenetic reprogramming

Wu, J., Xu, X., Lee, E. J., Shull, A. Y., Pei, L., Awan, F., Wang, X., Choi, J-H., Deng, L., Xin, H. B., Zhong, W., Liang, J., Miao, Y., Wu, Y., Fan, L., Li, J., Xu, W. & Shi, H., 2016, In : Oncotarget. 7, 26, p. 40558-40570 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Predicting DNA Methylation State of CpG Dinucleotide Using Genome Topological Features and Deep Networks

Wang, Y., Liu, T., Xu, D., Shi, H., Zhang, C., Mo, Y. Y. & Wang, Z., Jan 22 2016, In : Scientific reports. 6, 19598.

Research output: Contribution to journalArticle

33 Scopus citations

Prevalence of cervical cancer and associated mortality in Grenada, 2000-2010

Bahadoor-Yetman, A., Riley, L., Gibbons, A., Fields, P. J., Mapp-Alexander, V., Hage, R. & Baldwin, A., Apr 2016, In : Revista Panamericana de Salud Publica/Pan American Journal of Public Health. 39, 4, p. 194-199 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Prohibitin as the Molecular Binding Switch in the Retinal Pigment Epithelium

Sripathi, S. R., Sylvester, OD. D., He, W., Moser, T., Um, J. Y., Lamoke, F., Ramakrishna, W., Bernstein, P. S., Bartoli, M. & Jahng, W. J., Feb 1 2016, In : Protein Journal. 35, 1

Research output: Contribution to journalArticle

9 Scopus citations

Prostate-specific membrane antigen targeted protein contrast agents for molecular imaging of prostate cancer by MRI

Pu, F., Salarian, M., Xue, S., Qiao, J., Feng, J., Tan, S., Patel, A., Li, X., Mamouni, K., Hekmatyar, K., Zou, J., Wu, D. & Yang, J. J., Jul 7 2016, In : Nanoscale. 8, 25, p. 12668-12682 15 p.

Research output: Contribution to journalArticle

21 Scopus citations

RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA1 expression

Wang, Y., Deng, O., Feng, Z., Du, Z., Xiong, X., Lai, J., Yang, X., Xu, M., Wang, H., Taylor, D., Yan, C., Chen, C., Difeo, A., Ma, Z. & Zhang, J., Mar 17 2016, In : Oncogene. 35, 11, p. 1363-1372 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Roles of distal and genic methylation in the development of prostate tumorigenesis revealed by genome-wide DNA methylation analysis

Wang, Y., Jadhav, R. R., Liu, J., Wilson, D., Chen, Y., Thompson, I. M., Troyer, D. A., Hernandez, J., Shi, H., Leach, R. J., Huang, T. H. M. & Jin, V. X., 2016, In : Scientific reports. 6, 22051.

Research output: Contribution to journalArticle

12 Scopus citations

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation

Lemos, H., Mohamed, E., Huang, L., Ou, R., Pacholczyk, G., Arbab, A. S., Munn, D. & Mellor, A. L., Apr 15 2016, In : Cancer Research. 76, 8, p. 2076-2081 6 p.

Research output: Contribution to journalArticle

85 Scopus citations

Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1

Xie, X., Tang, S. C., Cai, Y., Pi, W., Deng, L., Wu, G., Chavanieu, A. & Teng, Y., 2016, In : Oncotarget. 7, 36, p. 58111-58120 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Targeted next generation sequencing approach identifies eighteen new candidate genes in normosmic hypogonadotropic hypogonadism and Kallmann syndrome

Quaynor, S. D., Bosley, M. E., Duckworth, C. G., Porter, K. R., Kim, S. H., Kim, H. G., Chorich, L. P., Sullivan, M. E., Choi, J. H., Cameron, R. S. & Layman, L. C., Dec 5 2016, In : Molecular and Cellular Endocrinology. 437, p. 86-96 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models

Wu, Q., Bhole, A., Qin, H., Karp, J., Malek, S., Cowell, J. K. & Ren, M., 2016, In : Oncotarget. 7, 31, p. 49733-49742 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers

Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E., Melnik, M. K., Korkaya, H., Maroun, C. R., Christensen, J. G., Steensma, M. R., Boerner, J. L. & Graveel, C. R., 2016, In : Oncotarget. 7, 43, p. 69903-69915 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress

Zhang, Y., Lai, J., Du, Z., Gao, J., Yang, S., Gorityala, S., Xiong, X., Deng, O., Ma, Z., Yan, C., Susana, G., Xu, Y. & Zhang, J., Jun 7 2016, In : Oncotarget. 7, 23, p. 34688-34702 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

The andean anticancer herbal product BIRM causes destabilization of androgen receptor and induces caspase-8 mediated-apoptosis in prostate cancer

Shamaladevi, N., Araki, S., Lyn, D. A., Ayyathurai, R., Gao, J., Lokeshwar, V. B., Navarrete, H. & Lokeshwar, B. L., 2016, In : Oncotarget. 7, 51, p. 84201-84213 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation

Zhao, J., Li, X., Guo, M., Yu, J. & Yan, C., May 4 2016, In : BMC Genomics. 17, 1, 335.

Research output: Contribution to journalArticle

28 Scopus citations

The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells

Lu, C., Redd, P. S., Lee, J. R., Savage, N. & Liu, K., Dec 1 2016, In : OncoImmunology. 5, 12, e1247135.

Research output: Contribution to journalArticle

60 Scopus citations

The stress-responsive gene ATF3 mediates dichotomous UV responses by regulating the Tip60 and p53 proteins

Cui, H., Li, X., Han, C., Wang, Q. E., Wang, H., Ding, H. F., Zhang, J. & Yan, C., May 13 2016, In : Journal of Biological Chemistry. 291, 20, p. 10847-10857 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Tracing anti-cancer and cancer-promoting actions of all-trans retinoic acid in breast cancer to a RARa epigenetic mechanism of mammary epithelial cell fate

Rossetti, S., Ren, M. Q., Visconti, N., Corlazzoli, F., Gagliostro, V., Somenzi, G., Yao, J., Sun, Y. & Sacchi, N., 2016, In : Oncotarget. 7, 52, p. 87064-87080 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells

Liu, M., Xia, Y., Ding, J., Ye, B., Zhao, E., Choi, J. H., Alptekin, A., Yan, C., Dong, Z., Huang, S., Yang, L., Cui, H., Zha, Y. & Ding, H. F., Oct 4 2016, In : Cell Reports. 17, 2, p. 609-623 15 p.

Research output: Contribution to journalArticle

20 Scopus citations

Transformation of human CD34+ hematopoietic progenitor cells with DEK-NUP214 induces AML in an immunocompromised mouse model

Qin, H., Malek, S., Cowell, J. K. & Ren, M., Oct 27 2016, In : Oncogene. 35, 43, p. 5686-5691 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility

Zhou, H. M., Fang, Y. Y., Weinberger, P. M., Ding, L. L., Cowell, J. K., Hudson, F. Z., Ren, M., Lee, J. R., Chen, Q. K., Su, H., Dynan, W. S. & Lin, Y., Feb 4 2016, In : BMC Cancer. 16, 1, 55.

Research output: Contribution to journalArticle

18 Scopus citations

Triple negative breast cancer development can be selectively suppressed by sustaining an elevated level of cellular cyclic AMP through simultaneously blocking its efflux and decomposition

Wang, W., Li, Y., Zhu, J. Y., Fang, D., Ding, H., Dong, Z., Jing, Q., Su, S. B. & Huang, S., 2016, In : Oncotarget. 7, 52, p. 87232-87245 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

Huang, L., Ou, R., Rabelo de Souza, G., Cunha, T. M., Lemos, H., Mohamed, E., Li, L., Pacholczyk, G., Randall, J., Munn, D. H. & Mellor, A. L., May 2016, In : PLoS Pathogens. 12, 5, e1005615.

Research output: Contribution to journalArticle

19 Scopus citations

WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling

Teng, Y., Pi, W., Wang, Y. & Cowell, J. K., Sep 1 2016, In : Oncogene. 35, 35, p. 4633-4640 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

YM155 inhibits topoisomerase function

Hong, M., Ren, M. Q., Silva, J., Paul, A., Wilson, W. D., Schroeder, C., Weinberger, P., Janik, J. & Hao, Z., Oct 13 2016, In : Anti-Cancer Drugs. 28, 2, p. 142-152 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

53BP1 promotes microhomology-mediated end-joining in G1-phase cells

Xiong, X., Du, Z., Wang, Y., Feng, Z., Fan, P., Yan, C., Willers, H. & Zhang, J., 2015, In : Nucleic Acids Research. 43, 3, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

27 Scopus citations
4 Scopus citations

A critical role of CXCR2 PDZ-mediated interactions in endothelial progenitor cell homing and angiogenesis

Hou, Y., Wu, Y., Farooq, S. M., Guan, X., Wang, S., Liu, Y., Oblak, J. J., Holcomb, J., Jiang, Y., Strieter, R. M., Lasley, R. D., Arbab, A. S., Sun, F., Li, C. & Yang, Z., Mar 1 2015, In : Stem Cell Research. 14, 2, p. 133-143 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

A federated network for translational cancer research using clinical data and biospecimens

Jacobson, R. S., Becich, M. J., Bollag, R. J., Chavan, G., Corrigan, J., Dhir, R., Feldman, M. D., Gaudioso, C., Legowski, E., Maihle, N. J., Mitchell, K., Murphy, M., Sakthivel, M., Tseytlin, E. & Weaver, J., Dec 15 2015, In : Cancer Research. 75, 24, p. 5194-5201 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4+ T cells

Lu, X., Ding, Z. C., Cao, Y., Liu, C., Habtetsion, T., Yu, M., Lemos, H., Salman, H., Xu, H., Mellor, A. L. & Zhou, G., Feb 15 2015, In : Journal of Immunology. 194, 4, p. 2011-2021 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy

Chaudhary, K., Shinde, R., Liu, H., Gnana-Prakasam, J. P., Veeranan-Karmegam, R., Huang, L., Ravishankar, B., Bradley, J., Kvirkvelia, N., McMenamin, M., Xiao, W., Kleven, D., Mellor, A. L., Madaio, M. P. & McGaha, T. L., Jun 15 2015, In : Journal of Immunology. 194, 12, p. 5713-5724 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation

Lamoke, F., Mazzone, V., Persichini, T., Maraschi, A., Harris, B. M., Venema, R. C., Colasanti, M., Gliozzi, M., Muscoli, C., Bartoli, M. & Mollace, V., May 3 2015, In : Journal of Neuroinflammation. 12, 1, 84.

Research output: Contribution to journalArticle

28 Scopus citations

Article watch: September 2015

Slaughter, C. A., Sep 1 2015, In : Journal of Biomolecular Techniques. 26, 3, p. 113-117 5 p.

Research output: Contribution to journalArticle

Article watch: December 2015

Slaughter, C. A., Dec 1 2015, In : Journal of Biomolecular Techniques. 26, 4, p. 150-156 7 p.

Research output: Contribution to journalArticle

Assessing heavy metal and PCB exposure from tap water by measuring levels in plasma from sporadic breast cancer patients, a pilot study

Zimeri, A. M., Robb, S. W., Hassan, S. M., Hire, R. R. & Davis, M. B., Dec 9 2015, In : International journal of environmental research and public health. 12, 12, p. 15683-15691 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Assessing myogenic response and vasoactivity in resistance mesenteric arteries using pressure myography

Jadeja, R. N., Rachakonda, V., Bagi, Z. & Khurana, S., Jul 6 2015, In : Journal of Visualized Experiments. 2015, 101, p. 1-7 7 p., e50997.

Research output: Contribution to journalArticle

8 Scopus citations

B cell-intrinsic IDO1 regulates humoral immunity to T cell-independent antigens

Shinde, R., Shimoda, M., Chaudhary, K., Liu, H., Mohamed, E., Bradley, J., Kandala, S., Li, X., Liu, K. & McGaha, T. L., Sep 1 2015, In : Journal of Immunology. 195, 5, p. 2374-2382 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Bone marrow derived myeloid cells orchestrate antiangiogenic resistance in glioblastoma through coordinated molecular networks

Achyut, B. R., Shankar, A., Iskander, A. S. M., Ara, R., Angara, K., Zeng, P., Knight, R. A., Scicli, A. G. & Arbab, A. S., Dec 28 2015, In : Cancer Letters. 369, 2, p. 416-26 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Can Brown Fat Win the Battle Against White Fat?

Elattar, S. & Satyanarayana, A., Oct 1 2015, In : Journal of Cellular Physiology. 230, 10, p. 2311-2317 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Canonical Wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation

Suryawanshi, A., Manoharan, I., Hong, Y., Swafford, D., Majumdar, T., Taketo, M. M., Manicassamy, B., Koni, P. A., Thangaraju, M., Sun, Z., Mellor, A. L., Munn, D. H. & Manicassamy, S., Apr 1 2015, In : Journal of Immunology. 194, 7, p. 3295-3304 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes

Bhagirath, D., Zhao, X., West, W. W., Qiu, F., Band, H. & Band, V., 2015, In : Oncotarget. 6, 11, p. 9018-9030 13 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Concentration-independent MRI of pH with a dendrimer-based pH-responsive nanoprobe

Bhuiyan, M. P. I., Aryal, M. P., Janic, B., Karki, K., Varma, N. R. S., Ewing, J. R., Arbab, A. S. & Ali, M. M., Nov 1 2015, In : Contrast Media and Molecular Imaging. 10, 6, p. 481-486 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Curcumin improves the tumoricidal effect of mitomycin C by suppressing ABCG2 expression in stem cell-like breast cancer cells

Zhou, Q., Ye, M., Lu, Y., Zhang, H., Chen, Q., Huang, S. & Su, S., Aug 25 2015, In : PloS one. 10, 8, e0136694.

Research output: Contribution to journalArticle

36 Scopus citations

Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets

Jain, A., Samykutty, A., Jackson, C., Browning, D., Bollag, W. B., Thangaraju, M., Takahashi, S. & Singh, S. R., Aug 28 2015, In : Cancer Letters. 365, 1, p. 122-131 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression

Yang, L., Fang, D., Chen, H., Lu, Y., Dong, Z., Ding, H. F., Jing, Q., Su, S. B. & Huang, S., 2015, In : Oncotarget. 6, 25, p. 20801-20812 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Deletion of the amino acid transporter SLC6A14 suppresses tumour growth in spontaneous mouse models of breast cancer

Babu, E., Bhutia, Y. D., Ramachandran, S., Gnana-Prakasam, J. P., Prasad, P. D., Thangaraju, M. & Ganapathy, V., Jul 1 2015, In : Biochemical Journal. 469, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Distinct transcript isoforms of the atypical chemokine receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) gene are expressed in lymphoblasts and altered isoform levels are associated with genetic ancestry and the duffy-null allele

Davis, M. B., Walens, A., Hire, R., Mumin, K., Brown, A. M., Ford, D. J., Howerth, E. W. & Monteil, M., Oct 16 2015, In : PloS one. 10, 10, 140098.

Research output: Contribution to journalArticle

8 Scopus citations