Biochemistry and Molecular Biology

Research Output 1968 2019

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1 Citation (Scopus)

Assessment of renal acidification capacity of stone formers by acid challenge test

Ahmed, A., Pendse, AK., Rajpurohit, S. K. & Singh, PP., 1992, In : Indian Journal of Clinical Biochemistry. 7, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Assignment of the human folate transporter gene to chromosome 21q22.3 by somatic cell hybrid analysis and in situ hybridization

Yang-Feng, T. L., Ma, Y. Y., Liang, R., Prasad, P. D., Leibach, F. H. & Ganapathy, V., May 25 1995, In : Biochemical and Biophysical Research Communications. 210, 3, p. 874-879 6 p.

Research output: Contribution to journalArticle

Folic Acid Transporters
Hybrid Cells
Chromosomes
In Situ Hybridization
Complementary DNA
9 Citations (Scopus)

Assignment of the locus ACONM to chromosome 22

Slaughter, C. A., Povey, S., Carritt, B., Solomon, E. & Bobrow, M., Jan 1 1978, In : Cytogenetic and Genome Research. 22, 1-6, p. 223-225 3 p.

Research output: Contribution to journalArticle

Minor Lymphocyte Stimulatory Loci
Chromosomes, Human, Pair 22
Aconitate Hydratase
Chromosomes, Human, Pair 9
Rodentia
1 Citation (Scopus)

Association of beta2-adrenergic receptor and insulin receptor substrate-1 polymorphisms with obesity in a Northern Indian population

Srivastava, N., Achyut, B. R., Prakash, J., Agarwal, C. G., Pant, D. C. & Mittal, B., May 2008, In : Indian Journal of Dermatology. 14, 2, p. 48-54 7 p.

Research output: Contribution to journalArticle

Adrenergic beta-2 Receptors
Insulin Receptor Substrate Proteins
Adrenergic Receptors
Obesity
Population
15 Citations (Scopus)

Association of cholesteryl ester transfer protein (TaqIB) and apolipoprotein E (HhaI) gene variants with obesity

Srivastava, N., Achyut, B. R., Prakash, J., Agarwal, C. G., Pant, D. C. & Mittal, B., Jul 2008, In : Molecular and Cellular Biochemistry. 314, 1-2, p. 171-7 7 p.

Research output: Contribution to journalArticle

Cholesterol Ester Transfer Proteins
Apolipoprotein E4
Apolipoproteins E
Blood pressure
Obesity
64 Citations (Scopus)

Association of hyaluronic acid family members (HAS1, HAS2, and HYAL-1) with bladder cancer diagnosis and prognosis

Kramer, M. W., Escudero, D. O., Lokeshwar, S. D., Golshani, R., Ekwenna, O. O., Acosta, K., Merseburger, A. S., Soloway, M. & Lokeshwar, V. B., Mar 15 2011, In : Cancer. 117, 6, p. 1197-1209 13 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Urinary Bladder Neoplasms
Neoplasms
Neoplasm Metastasis
Recurrence
151 Citations (Scopus)

Association of protein phosphatase 2A with polyoma virus medium tumor antigen

Walter, G., Ruediger, R., Slaughter, C. A. & Mumby, M., Jan 1 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 7, p. 2521-2525 5 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Polyomavirus
Neoplasm Antigens
Proteins
Simian virus 40
9 Citations (Scopus)

Associations between climate variables and asthma visits to accident and emergency facilities in Trinidad, West Indies

Ivey, M. A., Simeon, D. T., Juman, S., Hassanally, R., Williams, K. & Monteil, M. A., Jan 1 2001, In : Allergology International. 50, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

Trinidad and Tobago
West Indies
Climate
Accidents
Emergencies
24 Citations (Scopus)

Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells

Sukumari Ramesh, S., Laird, M. D., Singh, N., Vender, J. R., Alleyne, C. H. & Dhandapani, K. M., Nov 15 2010, In : Glia. 58, 15, p. 1858-1870 13 p.

Research output: Contribution to journalArticle

Hemin
Astrocytes
Glutathione
Cell Death
Apoptosis
9 Citations (Scopus)

A study of recurrent stone formers with special reference to renal tubular acidosis

Singh, P. P., Pendse, A. K., Ahmed, A., Ramavataram, D. V. & Rajpurohit, S. K., 1995, In : Urological Research. 23, 3, p. 201-3 3 p.

Research output: Contribution to journalArticle

Renal Tubular Acidosis
Citric Acid
Calcium
Ammonium Compounds
Acids
9 Citations (Scopus)

A synthetic manassantin a derivative inhibits hypoxia-inducible factor 1 and tumor growth

Lang, L., Liu, X., Li, Y., Zhou, Q., Xie, P., Yan, C. & Chen, X., Jun 12 2014, In : PloS one. 9, 6, e99584.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Tumors
chemical derivatives
Derivatives
neoplasms
85 Citations (Scopus)

A systematic evaluation of miRNA: MRNA interactions involved in the migration and invasion of breast cancer cells

Luo, D., Wilson, J. M., Harvel, N., Liu, J., Pei, L., Huang, S., Hawthorn, L. & Shi, H., Mar 5 2013, In : Journal of Translational Medicine. 11, 1, 57.

Research output: Contribution to journalArticle

MicroRNAs
Cells
Breast Neoplasms
Genes
Cell Line
7 Citations (Scopus)

Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice

Wang, Z., He, Y., Deng, W., Lang, L., Yang, H., Jin, B., Kolhe, R. B., Ding, H., Zhang, J., Hai, T. & Yan, C., Jan 4 2018, In : Oncogene. 37, 1, p. 18-27 10 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
Genomic Instability
Carcinogenesis
Neoplasms
DNA Damage

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc

Wang, L., Liu, Y., Du, T., Yang, H., Lei, L., Guo, M., Ding, H., Zhang, J., Wang, H., Chen, X. & Yan, C., Jan 1 2019, In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

Open Access
Activating Transcription Factor 3
Antiporters
Lipid Peroxidation
Glutathione
Cell Death
82 Citations (Scopus)

ATF3 represses 72-kDa type IV collagenase (MMP-2) expression by antagonizing p53-dependent trans-activation of the collagenase promoter

Yan, C., Wang, H. & Boyd, D. D., Mar 29 2002, In : Journal of Biological Chemistry. 277, 13, p. 10804-10812 9 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 8
Matrix Metalloproteinase 2
Collagenases
Matrix Metalloproteinases
Chemical activation
27 Citations (Scopus)

A transformation-associated complex involving tyrosine kinase signal adapter proteins and caldesmon links v-ErbB signaling to actin stress fiber disassembly

Mcmanus, M. J., Lingle, W. L., Salisbury, J. L. & Maihle, N. J., Oct 14 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 21, p. 11351-11356 6 p.

Research output: Contribution to journalArticle

Calmodulin-Binding Proteins
Stress Fibers
Protein-Tyrosine Kinases
Actins
Collagen
191 Citations (Scopus)

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis

Pabla, N., Huang, S., Mi, Q. S., Daniel, R. & Dong, Z., Mar 7 2008, In : Journal of Biological Chemistry. 283, 10, p. 6572-6583 12 p.

Research output: Contribution to journalArticle

Cisplatin
DNA Damage
Chemical activation
Apoptosis
DNA
171 Citations (Scopus)

A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue

Petch Lee, L. A., Harris, J., Raymond, V. W., Blasband, A., Lee, D. C. & Earp, H. S., Jan 1 1990, In : Molecular and Cellular Biology. 10, 6, p. 2973-2982 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Messenger RNA
Clone Cells
Epidermal Growth Factor
Hepatocytes
1 Citation (Scopus)

Atypical chemokine receptor 1 (DARC/ACKR1) in breast tumors is associated with survival, circulating chemokines, tumor-infiltrating immune cells, and African ancestry

Jenkins, B. D., Martini, R. N., Hire, R., Brown, A., Bennett, B., Brown, I., Howerth, E. W., Egan, M., Hodgson, J., Yates, C., Kittles, R., Chitale, D., Ali, H., Nathanson, D., Nikolinakos, P., Newman, L., Monteil, M. A. & Davis, M. B., Apr 1 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 4, p. 690-700 11 p.

Research output: Contribution to journalArticle

Open Access
Chemokine Receptors
Chemokines
Breast Neoplasms
Neoplasms
Alleles
50 Citations (Scopus)

Augmentation in expression of activation-induced genes differentiates memory from naive CD4+ T cells and is a molecular mechanism for enhanced cellular response of memory CD4+ T cells

Liu, K., Li, Y., Prabhu, V., Young, L., Becker, K. G., Munson, P. J. & Weng, N. P., Jun 15 2001, In : Journal of Immunology. 166, 12, p. 7335-7344 10 p.

Research output: Contribution to journalArticle

Transcriptional Activation
T-Lymphocytes
Complementary DNA
Clone Cells
Genes
12 Citations (Scopus)

Augmentation of the anticancer activity of CYT997 in human prostate cancer by inhibiting Src activity

Teng, Y., Cai, Y., Pi, W., Gao, L. & Shay, C., Jun 12 2017, In : Journal of Hematology and Oncology. 10, 1, 118.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Pharmaceutical Preparations
Microtubules
Neoplasms
Cell Survival
27 Citations (Scopus)

A Universal protein tag for delivery of SiRNA-Aptamer Chimeras

Liu, H. Y. & Gao, X., Nov 7 2013, In : Scientific Reports. 3, 3129.

Research output: Contribution to journalArticle

Small Interfering RNA
Proteins
RNA
RNA Interference
Complement System Proteins
57 Citations (Scopus)

AU-rich-element-dependent translation repression requires the cooperation of tristetraprolin and RCK/P54

Qi, M. Y., Wang, Z. Z., Zhang, Z., Shao, Q., Zeng, A., Li, X. Q., Li, W. Q., Wang, C., Tian, F. J., Li, Q., Zou, J., Qin, Y. W., Brewer, G., Huang, S. & Jing, Q., Mar 1 2012, In : Molecular and Cellular Biology. 32, 5, p. 913-928 16 p.

Research output: Contribution to journalArticle

Tristetraprolin
AU Rich Elements
Protein Biosynthesis
Messenger RNA
Tumor Necrosis Factor-alpha
243 Citations (Scopus)

Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury

Livingston, M. J., Liu, K., Luo, J. & Dong, Z., Jan 1 2010, In : American Journal of Pathology. 176, 3, p. 1181-1192 12 p.

Research output: Contribution to journalArticle

Autophagy
Reperfusion Injury
Kidney
Reperfusion
Ischemia
13 Citations (Scopus)

Autophosphorylation of Skeletal Muscle Myosin Light Chain Kinase

Gao, Z. H., Stull, J. T., Moomaw, C. R., Hsu, J. & Slaughter, C. A., Feb 1 1992, In : Biochemistry. 31, 26, p. 6126-6133 8 p.

Research output: Contribution to journalArticle

Skeletal Muscle Myosins
Myosin-Light-Chain Kinase
Calmodulin
Phosphorylation
Catalytic Domain
43 Citations (Scopus)

A π-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase

Medlock, A. E., Dailey, T. A., Ross, T. A., Dailey, H. A. & Lanzilotta, W. N., Nov 2 2007, In : Journal of Molecular Biology. 373, 4, p. 1006-1016 11 p.

Research output: Contribution to journalArticle

Ferrochelatase
Porphyrins
Heme
Enzymes
Proteins
13 Citations (Scopus)

Bacterial LPS up-regulated TLR3 expression is critical for antiviral response in human monocytes: Evidence for negative regulation by CYLD

Pan, Z. K., Fisher, C., Li, J. D., Jiang, Y., Huang, S. & Chen, L. Y., Jun 6 2011, In : International Immunology. 23, 6, p. 357-364 8 p., dxr019.

Research output: Contribution to journalArticle

Antiviral Agents
Monocytes
Leukocytes
TNF Receptor-Associated Factor 6
Toll-Like Receptors

B-arrestins regulate stem cell-like phenotype and response to chemotherapy in bladder cancer

Kallifatidis, G., Smith, D. K., Morera, D. S., Gao, J., Hennig, M. J., Hoy, J. J., Pearce, R. F., Dabke, I. R., Li, J., Merseburger, A. S., Kuczyk, M. A., Lokeshwar, V. B. & Lokeshwar, B. L., Apr 1 2019, In : Molecular cancer therapeutics. 18, 4, p. 801-811 11 p.

Research output: Contribution to journalArticle

Arrestins
gemcitabine
Urinary Bladder Neoplasms
Stem Cells
Phenotype
3 Citations (Scopus)

Baseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic response to combination therapy in children (PACTG 338)

Fiscus, S. A., Kovacs, A., Petch, L. A., Hu, C., Wiznia, A. A., Mofenson, L. M., Yogev, R., McIntosh, K., Pelton, S. I., Napravnik, S., Stanley, K. & Nachman, S. A., Mar 9 2007, In : AIDS Research and Therapy. 4, 2.

Research output: Contribution to journalArticle

Reverse Transcriptase Inhibitors
Nucleosides
Mutation
Zidovudine
Highly Active Antiretroviral Therapy
12 Citations (Scopus)

B cell-intrinsic IDO1 regulates humoral immunity to T cell-independent antigens

Shinde, R., Shimoda, M., Chaudhary, K., Liu, H., Mohamed, E., Bradley, J., Kandala, S., Li, X., Liu, K. & McGaha, T. L., Sep 1 2015, In : Journal of Immunology. 195, 5, p. 2374-2382 9 p.

Research output: Contribution to journalArticle

T Independent Antigens
Humoral Immunity
B-Lymphocytes
T-Lymphocytes
Autoimmunity
40 Citations (Scopus)

Biased g protein-coupled receptor signaling: New player in modulating physiology and pathology

Bologna, Z., Teoh, J. P., Bayoumi, A. S., Tang, Y. L. & Kim, I., Jan 1 2017, In : Biomolecules and Therapeutics. 25, 1, p. 12-25 14 p.

Research output: Contribution to journalArticle

Physiology
Pathology
G-Protein-Coupled Receptors
Arrestins
GTP-Binding Proteins
83 Citations (Scopus)

Bifidobacteria stabilize claudins at tight junctions and prevent intestinal barrier dysfunction in mouse necrotizing enterocolitis

Bergmann, K. R., Liu, S. X. L., Tian, R., Kushnir, A., Turner, J. R., Li, H. L., Chou, P. M., Weber, C. R. & De Plaen, I. G., May 2013, In : American Journal of Pathology. 182, 5, p. 1595-1606 12 p.

Research output: Contribution to journalArticle

Claudins
Necrotizing Enterocolitis
Bifidobacterium
Tight Junctions
Claudin-4
274 Citations (Scopus)

BIN1 is a novel MYC-interacting protein with features of a tumour suppressor

Sakamuro, D., Elliott, K. J., Wechsler-Reya, R. & Prendergast, G. C., Sep 1 1996, In : Nature Genetics. 14, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasms
Proteins
Oncogene Proteins
Cell Cycle Checkpoints
64 Citations (Scopus)

Bin1 mediates apoptosis by c-Myc in transformed primary cells

DuHadaway, J. B., Sakamuro, D., Ewert, D. L. & Prendergast, G. C., Apr 1 2001, In : Cancer Research. 61, 7, p. 3151-3156 6 p.

Research output: Contribution to journalArticle

Cell Death
Capital Punishment
Apoptosis
Tumor Suppressor Proteins
Genes
12 Citations (Scopus)

Bioimaging using the optimized nonlinear optical properties of ZnO nanoparticles

Urban, B. E., Neogi, P., Senthilkumar, K., Rajpurohit, S. K., Jagadeeshwaran, P., Kim, S., Fujita, Y. & Neogi, A., 2012, In : Selected Topics in Quantum Electronics, IEEE Journal of. 18, 4, p. 1451-1456 6 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Biological functions of SLC5A8, a candidate tumour suppressor

Ganapathy, V., Gopal, E., Miyauchi, S. & Prasad, P. O., Feb 1 2005, In : Biochemical Society Transactions. 33, 1, p. 237-240 4 p.

Research output: Contribution to journalArticle

Volatile Fatty Acids
Tumors
Genes
Butyrates
Niacin
16 Citations (Scopus)

BKM1740, an acyl-tyrosine bisphosphonate amide derivative, inhibits the bone metastatic growth of human prostate cancer cells by inducing apoptosis

Seong, I. S., Gera, L., Zhau, H. E., Wei, P. Q., Iqbal, S., Johnson, N. A., Zhang, S., Zayzafoon, M., Stewart, J., Wang, R., Chung, L. W. K. & Wu, D., Oct 1 2008, In : Clinical Cancer Research. 14, 19, p. 6198-6206 9 p.

Research output: Contribution to journalArticle

Bone Development
Diphosphonates
Prostatic Neoplasms
Apoptosis
Bone and Bones
87 Citations (Scopus)

Bladder tumor markers for monitoring recurrence and screening comparison of hyaluronic acid-hyaluronidase and BTA-stat tests

Lokeshwar, V. B., Schroeder, G. L., Selzer, M. G., Hautmann, S. H., Posey, J. T., Duncan, R. C., Watson, R., Rose, L., Markowitz, S. & Soloway, M. S., Jul 1 2002, In : Cancer. 95, 1, p. 61-72 12 p.

Research output: Contribution to journalArticle

Hyaluronoglucosaminidase
Hyaluronic Acid
Tumor Biomarkers
Urinary Bladder Neoplasms
Urinary Bladder
91 Citations (Scopus)
Histone Deacetylases
Butyrates
Propionates
Fermentation
Dendritic Cells
5 Citations (Scopus)

Blood lead levels in primary school children in Trinidad and Tobago

Rajkumar, W. S., Manohar, J., Doon, R., Siung-Chang, A., Chang-Yen, I. & Monteil, M., May 15 2006, In : Science of the Total Environment. 361, 1-3, p. 81-87 7 p.

Research output: Contribution to journalArticle

Blood
Lead
blood
Industrial poisons
baseline survey
3 Citations (Scopus)

Blood utilization for elective general surgery at the Port-of-Spain General Hospital.

Monteil, M. A. & Naraynsingh, V., Dec 1 1986, In : West Indian Medical Journal. 35, 4, p. 293-294 2 p.

Research output: Contribution to journalArticle

Hospital Surgery Department
Blood Grouping and Crossmatching
Trinidad and Tobago
Blood Banks
Hospital Departments
331 Citations (Scopus)

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

Kato, Y., Tapping, R. I., Huang, S., Watson, M. H., Ulevitch, R. J. & Lee, J. D., Oct 15 1998, In : Nature. 395, 6703, p. 713-716 4 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Cell Proliferation
Mitogen-Activated Protein Kinases
Cell Cycle
Mitogen-Activated Protein Kinase Kinases
19 Citations (Scopus)

Bone marrow derived myeloid cells orchestrate antiangiogenic resistance in glioblastoma through coordinated molecular networks

Achyut, B. R., Shankar, A., Iskander, A. S. M., Ara, R., Angara, K., Zeng, P., Knight, R. A., Scicli, A. G. & Arbab, A. S., Dec 28 2015, In : Cancer Letters. 369, 2, p. 416-26 11 p.

Research output: Contribution to journalArticle

Myeloid Cells
Glioblastoma
Bone Marrow
Tumor Microenvironment
Immunosuppressive Agents
10 Citations (Scopus)

Bone marrow-derived stromal cells (BMSCs) interact with fibroblasts in accelerating wound healing

Dulchavsky, D., Gao, X., Liu, Y. B., Deeb, D., Arbab, A. S., McIntosh, K., Dulchavsky, S. A. & Gautam, S. C., Dec 1 2008, In : Journal of Investigative Surgery. 21, 5, p. 270-279 10 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Wound Healing
Fibroblasts
Wounds and Injuries
Chemotaxis
124 Citations (Scopus)

Bradykinin stimulates NF-κB activation and interleukin 1β gene expression in cultured human fibroblasts

Pan, Z. K., Zuraw, B. L., Lung, C. C., Prossnitz, E. R., Browning, D. D. & Ye, R. D., Nov 1 1996, In : Journal of Clinical Investigation. 98, 9, p. 2042-2049 8 p.

Research output: Contribution to journalArticle

Bradykinin
Interleukin-1
Fibroblasts
Gene Expression
Chloramphenicol O-Acetyltransferase
22 Citations (Scopus)

Brain perfusion measured by flow-sensitive alternating inversion recovery (FAIR) and dynamic susceptibility contrast-enhanced magnetic resonance imaging: Comparison with nuclear medicine technique

Arbab, A. S., Aoki, S., Toyama, K., Kumagai, H., Arai, T., Kabasawa, H., Takahashi, Y. & Araki, T., Jan 1 2001, In : European Radiology. 11, 4, p. 635-641 7 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Nuclear Medicine
Perfusion Imaging
Inosine Monophosphate
Perfusion
2 Citations (Scopus)

Breast cancer heterogeneity: Need to review current treatment strategies

Malik, F., Korkaya, H., Clouthier, S. G. & Wicha, M. S., Dec 1 2012, In : Current Breast Cancer Reports. 4, 4, p. 225-231 7 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Breast Neoplasms
Therapeutics
Stem Cell Research
Neoplasms
23 Citations (Scopus)

Breast cancer stem cells: We've got them surrounded

Korkaya, H. & Wicha, M. S., Feb 1 2013, In : Clinical Cancer Research. 19, 3, p. 511-513 3 p.

Research output: Contribution to journalArticle

Interleukin-8 Receptors
Tumor Microenvironment
Neoplastic Stem Cells
Breast Neoplasms
Therapeutics
397 Citations (Scopus)

Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks

Liu, S., Ginestier, C., Ou, S. J., Clouthier, S. G., Patel, S. H., Monville, F., Korkaya, H., Heath, A., Dutcher, J., Kleer, C. G., Jung, Y., Dontu, G., Taichman, R. & Wicha, M. S., Jan 15 2011, In : Cancer Research. 71, 2, p. 614-624 11 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Mesenchymal Stromal Cells
Breast Neoplasms
Cytokines
Heterografts
59 Citations (Scopus)

Brief hyperglycaemia in the early pregnant rat increases fetal weight at term by stimulating placental growth and affecting placental nutrient transport

Ericsson, A., Säljö, K., Sjöstrand, E., Jansson, N., Prasad, P. D., Powell, T. L. & Jansson, T., Jun 1 2007, In : Journal of Physiology. 581, 3, p. 1323-1332 10 p.

Research output: Contribution to journalArticle

Fetal Weight
Hyperglycemia
Food
Pregnancy
Injections