Biochemistry and Molecular Biology

Curcumin analogue UBS109 prevents bone loss in breast cancer bone metastasis mouse model: Involvement in osteoblastogenesis and osteoclastogenesis

Yamaguchi, M., Zhu, S., Zhang, S., Wu, D., Moore, T. M., Snyder, J. P. & Shoji, M., Jul 2014, In : Cell and Tissue Research. 357, 1, p. 245-252 8 p.

Research output: Contribution to journal › Article

14 Scopus citations

Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects

Zhou, Q. M., Wang, X. F., Liu, X. J., Zhang, H., Lu, Y. Y., Huang, S. & Su, S. B., Sep 1 2011, In : European Journal of Cancer. 47, 14, p. 2240-2247 8 p.

Research output: Contribution to journal › Article

33 Scopus citations

Curcumin improves the tumoricidal effect of mitomycin C by suppressing ABCG2 expression in stem cell-like breast cancer cells

Zhou, Q., Ye, M., Lu, Y., Zhang, H., Chen, Q., Huang, S. & Su, S., Aug 25 2015, In : PloS one. 10, 8, e0136694.

Research output: Contribution to journal › Article

33 Scopus citations

Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets

Jain, A., Samykutty, A., Jackson, C., Browning, D., Bollag, W. B., Thangaraju, M., Takahashi, S. & Singh, S. R., Aug 28 2015, In : Cancer Letters. 365, 1, p. 122-131 10 p.

Research output: Contribution to journal › Article

21 Scopus citations

Curcumin modulates microRNA-203-mediated regulation of the Src-Akt axis in bladder cancer

Saini, S., Arora, S., Majid, S., Shahryari, V., Chen, Y., Deng, G., Yamamura, S., Ueno, K. & Dahiya, R., Oct 2011, In : Cancer Prevention Research. 4, 10, p. 1698-1709 12 p.

Research output: Contribution to journal › Article

Open Access

149 Scopus citations

Cutting edge: IRF8 regulates bax transcription in vivo in primary myeloid cells

Yang, J., Hu, X., Zimmerman, M., Torres, C. M., Yang, D., Smith, S. B. & Liu, K., Nov 1 2011, In : Journal of Immunology. 187, 9, p. 4426-4430 5 p.

Research output: Contribution to journal › Article

16 Scopus citations

CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

Ginestier, C., Liu, S., Diebel, M. E., Korkaya, H., Luo, M., Brown, M., Wicinski, J., Cabaud, O., Charafe-Jauffret, E., Birnbaum, D., Guan, J. L., Dontu, G. & Wicha, M. S., Feb 1 2010, In : Journal of Clinical Investigation. 120, 2, p. 485-497 13 p.

Research output: Contribution to journal › Article

537 Scopus citations

CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma

Angara, K., Borin, T. F., Rashid, M. H., Lebedyeva, I., Ara, R., Lin, P. C., Iskander, A. S. M., Bollag, R. J., Achyut, B. R. & Arbab, A. S., Oct 2018, In : Neoplasia (United States). 20, 10, p. 1070-1082 13 p.

Research output: Contribution to journal › Article

8 Scopus citations

Cyclic 3′,5′-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia

Kwon, I. K., Wang, R., Prakash, N., Bozard, R., Baudino, T. A., Liu, K., Thangaraju, M., Dong, Z. & Browning, D. D., Dec 1 2011, In : Cancer. 117, 23, p. 5282-5293 12 p.

Research output: Contribution to journal › Article

2 Scopus citations

Cyclic-GMP-elevating agents suppress polyposis in Apc ^Min mice by targeting the preneoplastic epithelium

Sharman, S. K., Islam, B. N., Hou, Y., Singh, N., Berger, F. G., Sridhar, S., Yoo, W. & Browning, D. D., Feb 2018, In : Cancer Prevention Research. 11, 2, p. 81-91 11 p.

Research output: Contribution to journal › Article

9 Scopus citations

Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression

Yang, L., Fang, D., Chen, H., Lu, Y., Dong, Z., Ding, H. F., Jing, Q., Su, S. B. & Huang, S., 2015, In : Oncotarget. 6, 25, p. 20801-20812 12 p.

Research output: Contribution to journal › Article

31 Scopus citations

Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression

Mao, L., Ding, J., Perdue, A., Yang, L., Zha, Y., Ren, M., Huang, S., Cui, H. & Ding, H. F., Aug 16 2012, In : Oncogene. 31, 33, p. 3785-3795 11 p.

Research output: Contribution to journal › Article

14 Scopus citations

CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells

Chen, L., Tang, S., Zhang, F. F., Garcia, V., Falck, J. R., Schwartzman, M. L., Arbab, A. S. & Guo, A. M., Jun 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 6, p. H1468-H1479

Research output: Contribution to journal › Article

1 Scopus citations

Cystathionine beta synthase expression in mouse retina

Markand, S., Tawfik, A., Ha, Y., Gnana-Prakasam, J., Sonne, S., Ganapathy, V., Sen, N., Xian, M. & Smith, S. B., May 1 2013, In : Current Eye Research. 38, 5, p. 597-604 8 p.

Research output: Contribution to journal › Article

11 Scopus citations

Cysteine redox sensor in PKGIα enables oxidant-induced activation

Burgoyne, J. R., Madhani, M., Cuello, F., Charles, R. L., Brennan, J. P., Schröder, E., Browning, D. D. & Eaton, P., Sep 7 2007, In : Science. 317, 5843, p. 1393-1397 5 p.

Research output: Contribution to journal › Article

332 Scopus citations

Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis

Liu, H. Y., Zheng, G., Treber, M., Dai, J. & Woldegiorgis, G., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 4524-4531 8 p.

Research output: Contribution to journal › Article

10 Scopus citations

Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer

Pejovic, T., Yates, J. E., Liu, H. Y., Hays, L. E., Akkari, Y., Torimaru, Y., Keeble, W., Rathbun, R. K., Rodgers, W. H., Bale, A. E., Ameziane, N., Zwaan, C. M., Errami, A., Thuillier, P., Cappuccini, F., Olson, S. B., Cain, J. M. & Bagby, G. C., Sep 15 2006, In : Cancer Research. 66, 18, p. 9017-9025 9 p.

Research output: Contribution to journal › Article

37 Scopus citations

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In : International journal of molecular sciences. 19, 2, 577.

Research output: Contribution to journal › Article

2 Scopus citations

Cytokine gene polymorphisms and the pathology of chronic gastritis

Moorchung, N., Srivastava, A. N., Gupta, N. K., Ghoshal, U. C., Achyut, B. R. & Mittal, B., May 2007, In : Singapore Medical Journal. 48, 5, p. 447-54 8 p.

Research output: Contribution to journal › Article

16 Scopus citations

Cytotoxicity evaluation and antimicrobial studies of starch capped water soluble copper nanoparticles

Valodkar, M., Rathore, P. S., Jadeja, R. N., Thounaojam, M., Devkar, R. V. & Thakore, S., Jan 30 2012, In : Journal of Hazardous Materials. 201-202, p. 244-249 6 p.

Research output: Contribution to journal › Article

78 Scopus citations

Cytotoxicity evaluation and hepatoprotective potential of bioassay guided fractions from Feronia limmonia Linn leaf

Jain, M., Kapadia, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Mishra, S. H., Dec 2011, In : Asian Pacific Journal of Tropical Biomedicine. 1, 6, p. 443-447 5 p.

Research output: Contribution to journal › Article

37 Scopus citations

Data on the role of miR-144 in regulating fetal hemoglobin production in retinal pigmented epithelial cells

Jadeja, R. N. & Martin, P. M., Feb 2020, In : Data in Brief. 28, 104874.

Research output: Contribution to journal › Article

Open Access

Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Jadeja, R. N., Urrunaga, N. H., Ahmad, D. & Khurana, S., Mar 1 2016, In : Data in Brief. 6, p. 405-409 5 p.

Research output: Contribution to journal › Article

1 Scopus citations

Death of retinal neurons in streptozotocin-induced diabetic mice

Martin, P. M., Roon, P., Van Ells, T. K., Ganapathy, V. & Smith, S. B., Sep 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 9, p. 3330-3336 7 p.

Research output: Contribution to journal › Article

325 Scopus citations

Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to fas ligand-induced apoptosis in vitro and tumor suppression in vivo

Yang, D., Torres, C. M., Bardhan, K., Zimmerman, M., McGaha, T. L. & Liu, K., May 1 2012, In : Journal of Immunology. 188, 9, p. 4441-4449 9 p.

Research output: Contribution to journal › Article

59 Scopus citations

Defective antibody-mediated opsonisation of S. pneumoniae in high risk patients detected by flow cytometry

Obaro, S. K., Henderson, D. C. & Monteil, M. A., Jan 1996, In : Immunology Letters. 49, 1-2, p. 83-89 7 p.

Research output: Contribution to journal › Article

11 Scopus citations

Defective T-cell receptor-induced apoptosis of T cells and rejection of transplanted immunogenic tumors in p53^-/- mice

Singh, N., Huang, L. & Qin, H., Feb 1 2010, In : European Journal of Immunology. 40, 2, p. 559-568 10 p.

Research output: Contribution to journal › Article

4 Scopus citations

Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study

Khodaverdian, V., Tapadar, S., MacDonald, I. A., Xu, Y., Ho, P. Y., Bridges, A., Rajpurohit, P., Sanghani, B. A., Fan, Y., Thangaraju, M., Hathaway, N. A. & Oyelere, A. K., Dec 1 2019, In : Scientific reports. 9, 1, 4802.

Research output: Contribution to journal › Article

Open Access

5 Scopus citations

Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock

Subramani, K., Chu, X., Warren, M., Lee, M., Lu, S., Singh, N. & Raju, R. P., Mar 1 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 3, p. 688-695 8 p.

Research output: Contribution to journal › Article

2 Scopus citations

Defining the enzyme binding domain of a ribonuclease III processing signal. Ethylation interference and hydroxyl radical footprinting using catalytically inactive RNase III mutants

Li, H. & Nicholson, A. W., Mar 15 1996, In : EMBO Journal. 15, 6, p. 1421-1433 13 p.

Research output: Contribution to journal › Article

63 Scopus citations

Degradation of Oxidized Insulin B Chain by the Multiproteinase Complex Macropain (Proteasome)

Dick, L. R., Moomaw, C. R., DeMartino, G. N. & Slaughter, C. A., Mar 1 1991, In : Biochemistry. 30, 10, p. 2725-2734 10 p.

Research output: Contribution to journal › Article

83 Scopus citations

Deletion of hemojuvelin, an iron-regulatory protein, in mice results in abnormal angiogenesis and vasculogenesis in retina along with reactive gliosis

Tawfik, A., Gnana-Prakasam, J. P., Smith, S. B. & Ganapathy, V., May 8 2014, In : Investigative Ophthalmology and Visual Science. 55, 6, p. 3616-3625 10 p.

Research output: Contribution to journal › Article

8 Scopus citations

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

Hong, Y., Manoharan, I., Suryawanshi, A., Shanmugam, A., Swafford, D., Ahmad, S., Chinnadurai, R., Manicassamy, B., He, Y., Mellor, A. L., Thangaraju, M., Munn, D. H. & Manicassamy, S., Apr 2 2016, In : OncoImmunology. 5, 4

Research output: Contribution to journal › Article

24 Scopus citations

Deletion of the amino acid transporter SLC6A14 suppresses tumour growth in spontaneous mouse models of breast cancer

Babu, E., Bhutia, Y. D., Ramachandran, S., Gnana-Prakasam, J. P., Prasad, P. D., Thangaraju, M. & Ganapathy, V., Jul 1 2015, In : Biochemical Journal. 469, 1, p. 17-23 7 p.

Research output: Contribution to journal › Article

35 Scopus citations

De novo design of selective antibiotic peptides by incorporation of unnatural amino acids

Hicks, R. P., Bhonsle, J. B., Venugopal, D., Koser, B. W. & Magill, A. J., Jun 28 2007, In : Journal of Medicinal Chemistry. 50, 13, p. 3026-3036 11 p.

Research output: Contribution to journal › Article

47 Scopus citations

De novo transcriptome sequencing in a songbird, the dark-eyed junco (Junco hyemalis): genomic tools for an ecological model system

Peterson, M. P., Whittaker, D. J., Ambreth, S., Sureshchandra, S., Buechlein, A., Podicheti, R., Choi, J. H., Lai, Z., Mockatis, K., Colbourne, J., Tang, H. & Ketterson, E. D., Jul 9 2012, In : BMC Genomics. 13, 1, 305.

Research output: Contribution to journal › Article

27 Scopus citations

Deoxycholylglycine, a conjugated secondary bile acid, reduces vascular tone by attenuating Ca²⁺ sensitivity via rho kinase pathway

Jadeja, R. N., Thounaojam, M. C., Bartoli, M. & Khurana, S., Jun 1 2018, In : Toxicology and Applied Pharmacology. 348, p. 14-21 8 p.

Research output: Contribution to journal › Article

Derangement of a factor upstream of RARalpha triggers the repression of a pleiotropic epigenetic network.

Corlazzoli, F., Rossetti, S., Bistulfi, G., Ren, M. & Sacchi, N., 2009, In : PloS one. 4, 1, p. e4305

Research output: Contribution to journal › Article

Open Access

17 Scopus citations

Deregulation of apoptotic factors Bcl-xL and Bax confers apoptotic resistance to myeloid-derived suppressor cells and contributes to their persistence in cancer

Hu, X., Bardhan, K., Paschall, A. V., Yang, D., Waller, J. L., Park, M. A., Nayak, A., Samuel, T. A., Abrams, S. I. & Liu, K., Jun 28 2013, In : Journal of Biological Chemistry. 288, 26, p. 19103-19115 13 p.

Research output: Contribution to journal › Article

39 Scopus citations

Descriptive epidemiology of asthma in Trinidad, West Indies

Monteil, M. A., Juman, S., Hassanally, R., Williams, K. P., Pierre, L., Rahaman, M., Singh, H. & Trinidade, A., Jan 1 2000, In : Journal of Asthma. 37, 8, p. 677-684 8 p.

Research output: Contribution to journal › Article

19 Scopus citations

Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity

Manfredini, S., Pavan, B., Vertuani, S., Scaglianti, M., Compagnone, D., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Prasad, P. D. & Dalpiaz, A., Jan 31 2002, In : Journal of Medicinal Chemistry. 45, 3, p. 559-562 4 p.

Research output: Contribution to journal › Article

85 Scopus citations

Design, synthesis and biological activities of quinazoline containing sorafenib analogs as antitumor agents

Zhang, J., Wang, N., Xie, X., Yan, C., Fu, F., Yao, J. & Wang, H., Jun 1 2017, In : Wuhan University Journal of Natural Sciences. 22, 3, p. 239-246 8 p.

Research output: Contribution to journal › Article

1 Scopus citations

Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules

Manfredini, S., Vertuani, S., Pavan, B., Vitali, F., Scaglianti, M., Bortolotti, F., Biondi, C., Scatturin, A., Prasad, P. & Dalpiaz, A., Oct 15 2004, In : Bioorganic and Medicinal Chemistry. 12, 20, p. 5453-5463 11 p.

Research output: Contribution to journal › Article

23 Scopus citations

Detection and selection of lentiviral vector-transduced cells.

Cui, Y. & Chang, L. J., 2003, In : Methods in molecular biology (Clifton, N.J.). 229, p. 69-85 17 p.

Research output: Contribution to journal › Article

3 Scopus citations

Detection of differentially methylated regions using bayes factor for ordinal group responses

Dunbar, F., Xu, H., Ryu, D., Ghosh, S., Shi, H. & George, V., Sep 2019, In : Genes. 10, 9, 721.

Research output: Contribution to journal › Article

Open Access

1 Scopus citations

Detection of lung and chest tumours using⁹⁹tc^m-tetrofosmin comparison with ²⁰¹t1

Arbab, A. S., Toyama, K., Arak, T., Araki, T. & Koizumi, K., Jul 1998, In : Nuclear Medicine Communications. 19, 7, 1 p.

Research output: Contribution to journal › Article

8 Scopus citations

Determinants of Gli2 co-activation of wildtype and naturally truncated androgen receptors

Li, N., Chen, M., Truong, S., Yan, C. & Buttyan, R., Oct 2014, In : Prostate. 74, 14, p. 1400-1410 11 p.

Research output: Contribution to journal › Article

11 Scopus citations

Determining the effect of the incorporation of unnatural amino acids into antimicrobial peptides on the interactions with zwitterionic and anionic membrane model systems

Russell, A. L., Kennedy, A. M., Spuches, A. M., Gibson, W. S., Venugopal, D., Klapper, D., Srouji, A. H., Bhonsle, J. B. & Hicks, R. P., Nov 1 2011, In : Chemistry and Physics of Lipids. 164, 8, p. 740-758 19 p.

Research output: Contribution to journal › Article

13 Scopus citations

Development of a novel animal model to differentiate radiation necrosis from tumor recurrence

Kumar, S., Arbab, A. S., Jain, R., Kim, J., DeCarvalho, A. C., Shankar, A., Mikkelsen, T. & Brown, S. L., Jul 2012, In : Journal of Neuro-Oncology. 108, 3, p. 411-420 10 p.

Research output: Contribution to journal › Article

20 Scopus citations

Development of a partial fibronectin knockout transgenic mouse model

Manshouri, T., Huang, S., Sundaresan, A., Chakravarthy, M., Chakrabarty, S. & Albitar, M., Jan 1 1997, In : Transgenics. 2, 2, p. 167-174 8 p.

Research output: Contribution to journal › Article