Biochemistry and Molecular Biology

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Discovery, synthesis of novel fusidic acid derivatives possessed amino-terminal groups at the 3-hydroxyl position with anticancer activity

Ni, J., Guo, M., Cao, Y., Lei, L., Liu, K., Wang, B., Lu, F., Zhai, R., Gao, X., Yan, C., Wang, H. & Bi, Y., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 122-131 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Discovery and Validation of a Novel Neutrophil Activation Marker Associated with Obesity

Pan, Y., Choi, J-H., Shi, H., Zhang, L., Su, S. & Wang, X., Dec 1 2019, In : Scientific reports. 9, 1, 3433.

Research output: Contribution to journalArticle

1 Scopus citations

Disease tropism of c-erbB: Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation

Pelley, R. J., Maihle, N. J., Boerkoel, C., Shu, H. K., Carter, T. H., Moscovici, C. & Kung, H. J., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 18, p. 7164-7168 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Disruption of retinoic acid receptor alpha reveals the growth promoter face of retinoic acid

Somenzi, G., Sala, G., Rossetti, S., Ren, M. Q., Ghidoni, R. & Sacchi, N., Sep 5 2007, In : PloS one. 2, 9, e836.

Research output: Contribution to journalArticle

25 Scopus citations

Dissociated ROS production and ceramide generation in sulfasalazine-induced cell death in Raw 264.7 cells

Salh, B., Assi, K., Huang, S., O'Brien, L., Steinbrecher, U. & Gómez-Muñoz, A., Oct 1 2002, In : Journal of Leukocyte Biology. 72, 4, p. 790-799 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells

Putiri, E. L., Tiedemann, R. L., Thompson, J. J., Liu, C., Ho, T., Choi, J. H. & Robertson, K. D., Jun 23 2014, In : Genome Biology. 15, 6, R81.

Research output: Contribution to journalArticle

54 Scopus citations

Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome

Silva, M. J., Chang, C. S., Hu, T., Qin, H., Kitamura, E., Hawthorn, L., Ren, M. & Cowell, J. K., Dec 2019, In : Genomics. 111, 6, p. 1566-1573 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Distinct transcript isoforms of the atypical chemokine receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) gene are expressed in lymphoblasts and altered isoform levels are associated with genetic ancestry and the duffy-null allele

Davis, M. B., Walens, A., Hire, R., Mumin, K., Brown, A. M., Ford, D. J., Howerth, E. W. & Monteil, M., Oct 16 2015, In : PloS one. 10, 10, 140098.

Research output: Contribution to journalArticle

8 Scopus citations

Distribution and Short-term Prognostic Value of the 21-gene recurrence score in African American compared to White American breast cancer patients

Amro, A., Chen, Y., Barry, R., Susick, L., Bensenhaver, J., Proctor, E., Petersen, L., Nathanson, S. D., Ali, H., Loutfi, R., Chitale, D., Simonds, A., Kuklinski, M., Park, K. U., Davis, M. & Newman, L. A., Jul 1 2019, In : Breast Journal. 25, 4, p. 667-671 5 p.

Research output: Contribution to journalArticle

Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells

Bachmann, A., Hanke, B., Zawatzky, R., Soto, U., Van Riggelen, J., Zur Hausen, H. & Rösl, F., Jan 1 2002, In : Journal of Virology. 76, 1, p. 280-291 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma

Bennett, L. B., Schnabel, J. L., Kelchen, J. M., Taylor, K. H., Guo, J., Arthur, G. L., Papageorgio, C. N., Shi, H. & Caldwell, C. W., Sep 1 2009, In : Genes Chromosomes and Cancer. 48, 9, p. 828-841 14 p.

Research output: Contribution to journalArticle

52 Scopus citations

DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes, including interferon regulatory factor 8

Guo, C., Pei, L., Xiao, X., Wei, Q., Chen, J., Ding, H., Huang, S., Fan, G., Shi, H. & Dong, Z., Nov 2017, In : Kidney International. 92, 5, p. 1194-1205 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

DNA methylation represses IFN-γ-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells

McGough, J. M., Yang, D., Huang, S., Georgi, D., Hewitt, S. M., Röcken, C., Tänzer, M., Ebert, M. P. A. & Liu, K., Dec 1 2008, In : Molecular Cancer Research. 6, 12, p. 1841-1851 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

DNA methyltransferase 1–mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1– driven leukemogenesis

Hu, T., Chong, Y., Cai, B., Liu, Y., Lu, S. & Cowell, J. K., Nov 29 2019, In : Journal of Biological Chemistry. 294, 48, p. 18122-18130 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells

Fukuhara, S., Chang, I., Mitsui, Y., Chiyomaru, T., Yamamura, S., Majid, S., Saini, S., Hirata, H., Deng, G., Gill, A., Wong, D. K., Shiina, H., Nonomura, N., Dahiya, R. & Tanaka, Y., Jan 1 2014, In : Oncotarget. 5, 22, p. 11297-11307 11 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

Pathania, R., Ramachandran, S., Elangovan, S., Padia, R., Yang, P., Cinghu, S., Veeranan-Karmegam, R., Arjunan, P., Gnana-Prakasam, J. P., Sadanand, F., Pei, L., Chang, C. S., Choi, J. H., Shi, H., Manicassamy, S., Prasad, P. D., Sharma, S., Ganapathy, V., Jothi, R. & Thangaraju, M., Apr 22 2015, In : Nature communications. 6, 6910.

Research output: Contribution to journalArticle

114 Scopus citations

DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma

Poole, C. J., Zheng, W., Lodh, A., Yevtodiyenko, A., Liefwalker, D., Li, H., Felsher, D. W. & van Riggelen, J., Jan 1 2017, In : Oncotarget. 8, 44, p. 76898-76920 23 p.

Research output: Contribution to journalArticle

11 Scopus citations

Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation

Leu, Y. W., Rahmatpanah, F., Shi, H., Wei, S. H., Liu, J. C., Yan, P. S. & Huang, T. H. M., Oct 1 2003, In : Cancer Research. 63, 19, p. 6110-6115 6 p.

Research output: Contribution to journalArticle

128 Scopus citations

Down-regulation of BCRP/ABCG2 in colorectal and cervical cancer

Gupta, N., Martin, P. M., Miyauchi, S., Ananth, S., Herdman, A. V., Martindale, R. G., Podolsky, R. & Ganapathy, V., May 5 2006, In : Biochemical and Biophysical Research Communications. 343, 2, p. 571-577 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Downregulation of IFN-γR in association with loss of Fas function is linked to tumor progression

Yang, D., Stewart, T. J., Smith, K. K., Georgi, D., Abrams, S. I. & Liu, K., Jan 15 2008, In : International Journal of Cancer. 122, 2, p. 350-362 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice

Naggar, H., Shamsul Ola, M., Martin, P. M., Huang, W., Bridges, C. C., Ganapathy, V. & Smith, S. B., Feb 11 2002, In : Investigative Ophthalmology and Visual Science. 43, 2, p. 556-563 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
14 Scopus citations

Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis

Cho, S. G., Du, Q., Huang, S. & Dong, Z., Jul 1 2010, In : American Journal of Physiology - Renal Physiology. 299, 1, p. F199-F206

Research output: Contribution to journalArticle

47 Scopus citations

Drugs of abuse and placental transport

Ganapathy, V., Prasad, P. D., Ganapathy, M. E. & Leibach, F. H., Jun 14 1999, In : Advanced Drug Delivery Reviews. 38, 1, p. 99-110 12 p.

Research output: Contribution to journalArticle

52 Scopus citations

Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy

Wang, Q., Navitskaya, S., Chakravarthy, H., Huang, C., Kady, N., Lydic, T. A., Chen, Y. E., Yin, K. J., Powell, F. L., Martin, P. M., Grant, M. B. & Busik, J. V., Sep 1 2016, In : EBioMedicine. 11, p. 138-150 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Dynamic 99tcm-ecd spet correlates well with 201tl indices in brain tumours

Miyazawa, N., Koizumi, K., Arbab, A. S. & Tohyama, K., Nov 1999, In : Nuclear Medicine Communications. 20, 11, p. 1023-1030 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Dynamic changes in the locus control region of erythroid progenitor cells demonstrated by polymerase chain reaction

Yoo, J., Herman, L. E., Li, C., Krantz, S. B. & Tuan Lo, D., Mar 15 1996, In : Blood. 87, 6, p. 2558-2567 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma

Tiedemann, R. L., Hlady, R. A., Hanavan, P. D., Lake, D. F., Tibes, R., Lee, J. H., Choi, J. H., Ho, T. H. & Robertson, K. D., Jan 1 2016, In : Oncotarget. 7, 2, p. 1927-1946 20 p.

Research output: Contribution to journalArticle

26 Scopus citations

Dynamic retrotransposition of ERV-9 LTR and L1 in the β-globin gene locus during primate evolution

Ling, J., Zhang, L., Jin, H., Pi, W., Kosteas, T., Anagnou, N. P., Goodman, M. & Tuan, D., Mar 2004, In : Molecular Phylogenetics and Evolution. 30, 3, p. 867-871 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Dynamic SPET parameters of 123I-MIBG cardiac imaging

Arbab, A. S., Koizumi, K., Toyama, K., Arai, T. & Araki, T., Jul 1999, In : Nuclear Medicine Communications. 20, 7, p. 617-622 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dysplastic hepatocytes develop nuclear inclusions in a mouse model of viral hepatitis

Thakur, P., Lamoke, F., Chaffin, J. M., Bartoli, M., Lee, J. R. & Duncan, M. B., Jun 16 2014, In : PloS one. 9, 6, e99872.

Research output: Contribution to journalArticle

4 Scopus citations

Dysregulated signaling pathways in the development of CNTRL-FGFR1–induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models

Ren, M., Qin, H., Kitamura, E. & Cowell, J. K., Aug 8 2013, In : Blood. 122, 6, p. 1007-1016 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Dysregulation of lipid and cholesterol metabolism in high fat diet fed hyperlipidemic rats: Protective effect of Sida rhomboidea. roxb leaf extract

Thounaojam, M., Jadeja, R., Ansarullah, Devkar, R. & Ramachandran, A. V., Jun 1 2009, In : Journal of Health Science. 55, 3, p. 413-420 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

E-Cadherin Engagement Stimulates Tyrosine Phosphorylation

Kinch, M. S., Petch, L., Zhong, C. & Burridge, K., Dec 1 1997, In : Cell Communication and Adhesion. 4, 6, p. 425-437 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Ectopic expression of nonliganded retinoic acid receptor β abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells

Arce, J. D. C., Soto, U., Van Riggelen, J., Schwarz, E., Zur Hausen, H. & Rösl, F., Oct 29 2004, In : Journal of Biological Chemistry. 279, 44, p. 45408-45416 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effectiveness of potassium citrate therapy in the management of nephrolithiasis

Rajpurohit, S. K., Pendse, AK., Barjatiya, MK. & Singh, PP., 1996, In : Urolithiasis. p. 450

Research output: Contribution to journalArticle

6 Scopus citations

Effect of curcumin on pro-angiogenic factors in the xenograft model of breast cancer

Ferreira, L. C., Arbab, A. S., Jardim-Perassi, B. V., Borin, T. F., Varma, N. R. S., Iskander, A. S. M., Shankar, A., Ali, M. M. & de Campos Zuccari, D. A. P., Dec 1 2015, In : Anti-Cancer Agents in Medicinal Chemistry. 15, 10, p. 1285-1296 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Effect of high fat diet on body weight and mammary tumor latency in MMTV-TGF-α mice

Cleary, M. P., Grande, J. P. & Maihle, N. J., Aug 1 2004, In : International Journal of Obesity. 28, 8, p. 956-962 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Effect of moderate caloric restriction and/or weight cycling on mammary tumor incidence and latency in MMTV-Neu female mice

Pape-Ansorge, K. A., Grande, J. P., Christensen, T. A., Maihle, N. J. & Cleary, M. P., Jan 1 2002, In : Nutrition and Cancer. 44, 2, p. 162-168 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Effect of α-domain substitution on the structure, property and function of human neuronal growth inhibitory factor

Ding, Z-C., Zheng, Q., Cai, B., Yu, W. H., Teng, X. C., Wang, Y., Zhou, G. M., Wu, H. M., Sun, H. Z., Zhang, M. J. & Huang, Z. X., Nov 1 2007, In : Journal of Biological Inorganic Chemistry. 12, 8, p. 1173-1179 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
15 Scopus citations

Effects of ferumoxides - Protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells

Janic, B., Iskander, A. S. M., Rad, A. M., Soltanian-Zadeh, H. & Arbab, A. S., Jun 25 2008, In : PloS one. 3, 6, e2499.

Research output: Contribution to journalArticle

20 Scopus citations

Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice

Dogan, S., Hu, X., Zhang, Y., Maihle, N. J., Grande, J. P. & Cleary, M. P., Dec 27 2007, In : Breast Cancer Research. 9, 6, R91.

Research output: Contribution to journalArticle

64 Scopus citations

Effects of modulating M3 muscarinic receptor activity on azoxymethane-induced liver injury in mice

Khurana, S., Jadeja, R., Twaddell, W., Cheng, K., Rachakonda, V., Saxena, N. & Raufman, J. P., Jan 1 2013, In : Biochemical Pharmacology. 86, 2, p. 329-338 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Effects of novel polyether ionophore hainanmycin on nutrient digestion, metabolism and ruminal characteristics of goats

Mingqiang, R., Zanming, S., Ruqian, Z., Tianshui, L. & Jie, C., Jan 1 1998, In : Journal of Animal and Feed Sciences. 7, 1, p. 21-28 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effects of targeted Bcl-2 expression in mitochondria or endoplasmic reticulum on renal tubular cell apoptosis

Bhatt, K., Feng, L., Pabla, N., Liu, K., Smith, S. & Dong, Z., Mar 1 2008, In : American Journal of Physiology - Renal Physiology. 294, 3, p. F499-F507

Research output: Contribution to journalArticle

37 Scopus citations

Effects of the incorporation of CHAPS into SDS micelles on neuropeptide-micelle binding: Separation of the role of electrostatic interactions from hydrophobic interactions

Whitehead, T. L., Jones, L. M. & Hicks, R. P., Jun 11 2001, In : Biopolymers. 58, 7, p. 593-605 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Effects of tyrosine kinase inhibitors and CXCR4 antagonist on tumor growth and angiogenesis in rat glioma model: MRI and protein analysis study

Ali, M. M., Kumar, S., Shankar, A., Varma, N. R. S., Iskander, A. S. M., Janic, B., Chwang, W. B., Jain, R., Babajeni-Feremi, A., Borin, T. F., Bagher-Ebadian, H., Brown, S. L., Ewing, J. R. & Arbab, A. S., Dec 2013, In : Translational Oncology. 6, 6, p. 660-669 10 p.

Research output: Contribution to journalArticle

21 Scopus citations