Biochemistry and Molecular Biology

Research Output 1968 2019

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7 Citations (Scopus)

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

Mangaonkar, A., Mondal, A. K., Fulzule, S., Pundkar, C., Park, E. J., Jillella, A., Kota, V., Xu, H., Savage, N. M., Shi, H., Munn, D. & Kolhe, R., Dec 1 2017, In : Scientific Reports. 7, 1, 12892.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Acute Myeloid Leukemia
Mortality
Messenger RNA
Bone Marrow
15 Citations (Scopus)

A novel protein kinase C (PKCε) is required for fMet-Leu-Phe-induced activation of NF-κB in human peripheral blood monocytes

Chen, L. Y., Doerner, A., Lehmann, P. F., Huang, S., Zhong, G. & Pan, Z. K., Jun 10 2005, In : Journal of Biological Chemistry. 280, 23, p. 22497-22501 5 p.

Research output: Contribution to journalArticle

N-Formylmethionine Leucyl-Phenylalanine
Protein Kinase C
Monocytes
Blood
Chemical activation
6 Citations (Scopus)

An RPE cell line as a useful in vitro model for studying retinoic acid receptor ß :Expression and affinity

Pavan, B., Dalpiaz, A., Biondi, C., Nieddu, M., De Luca, A., Prasad, P. D., Paganetto, G. & Favaloro, B., Dec 1 2008, In : Bioscience Reports. 28, 6, p. 327-334 8 p.

Research output: Contribution to journalArticle

Retinoic Acid Receptors
Cells
Cell Line
Ligands
Flavonoids
28 Citations (Scopus)

An SNP-based second-generation genetic map of Daphnia magna and its application to QTL analysis of phenotypic traits

Routtu, J., Hall, M. D., Albere, B., Beisel, C., Bergeron, R. D., Chaturvedi, A., Choi, J-H., Colbourne, J., Meester, L. D., Stephens, M. T., Stelzer, C. P., Solorzano, E., Thomas, W. K., Pfrender, M. E. & Ebert, D., Nov 27 2014, In : BMC Genomics. 15, 1, 1033.

Research output: Contribution to journalArticle

Daphnia
Single Nucleotide Polymorphism
Genome Size
Clone Cells
Genotype
295 Citations (Scopus)

Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

Shrimali, R. K., Yu, Z., Theoret, M. R., Chinnasamy, D., Restifo, N. P. & Rosenberg, S. A., Aug 1 2010, In : Cancer Research. 70, 15, p. 6171-6180 10 p.

Research output: Contribution to journalArticle

Adoptive Immunotherapy
Angiogenesis Inhibitors
Lymphocytes
Adoptive Transfer
Vascular Endothelial Growth Factor Receptor-2
398 Citations (Scopus)

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

Conley, S. J., Gheordunescu, E., Kakarala, P., Newman, B., Korkaya, H., Heath, A. N., Clouthier, S. G. & Wicha, M. S., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2784-2789 6 p.

Research output: Contribution to journalArticle

Angiogenesis Inhibitors
Neoplastic Stem Cells
Breast Neoplasms
Heterografts
Stem Cells
9 Citations (Scopus)

Antibacterial and anticancer activity of a series of novel peptides incorporating cyclic tetra-substituted Cαamino acids

Hicks, R. P., Jan 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 18, p. 4056-4065 10 p.

Research output: Contribution to journalArticle

Cyclic Peptides
Adenosine Monophosphate
Acids
Tics
Cells
14 Citations (Scopus)

Anticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation

Liu, Y., Gao, X., Deeb, D., Arbab, A. S., Dulchavsky, S. A. & Gauta, S. C., Aug 3 2012, In : Journal of Experimental Therapeutics and Oncology. 10, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Antineoplastic Agents
Interleukin-2
Cell Proliferation
T-Lymphocytes
Janus Kinases
3 Citations (Scopus)

Antigen-Specific antitumor responses induced by OX40 agonist are enhanced by the ido inhibitor indoximod

Berrong, Z., Mkrtichyan, M., Ahmad, S., Webb, M., Mohamed, E., Okoev, G., Matevosyan, A., Shrimali, R. K., Eid, R. A., Hammond, S., Janik, J. E. & Khleif, S. N., Feb 2018, In : Cancer Immunology Research. 6, 2, p. 201-208 8 p.

Research output: Contribution to journalArticle

Antigens
Neoplasms
Vaccines
Immunotherapy
Indoleamine-Pyrrole 2,3,-Dioxygenase
1 Citation (Scopus)

Anti-HER-2 therapy following severe trastuzumab-induced cardiac toxicity

Sadek, I., Keaton, M., Maihle, N. J. & Tang, S-C., Sep 1 2017, In : Genes and Diseases. 4, 3, p. 159-162 4 p.

Research output: Contribution to journalArticle

Toxicity
Thoracic Wall
Breast Neoplasms
Therapeutics
Disease control
17 Citations (Scopus)

Anti-inflammatory role of sesamin in STZ induced mice model of diabetic retinopathy

Ahmad, S., ElSherbiny, N. M., Jamal, M. S., Alzahrani, F. A., Haque, R., Khan, R., Zaidi, S. K., AlQahtani, M. H., Liou, G. I. & Bhatia, K., Jun 15 2016, In : Journal of Neuroimmunology. 295-296, p. 47-53 7 p.

Research output: Contribution to journalArticle

Diabetic Retinopathy
Streptozocin
Anti-Inflammatory Agents
Nitric Oxide Synthase Type II
Microglia
18 Citations (Scopus)

Anti-Jagged immunotherapy inhibits MDSCs and overcomes tumor-induced tolerance

Sierra, R. A., Trillo-Tinoco, J., Mohamed, E., Yu, L., Achyut, B. R., Arbab, A. S., Bradford, J. W., Osborne, B. A., Miele, L. & Rodriguez, P. C., Oct 15 2017, In : Cancer Research. 77, 20, p. 5628-5638 11 p.

Research output: Contribution to journalArticle

Immunotherapy
Neoplasms
T-Lymphocytes
Myeloid-Derived Suppressor Cells
Growth
31 Citations (Scopus)

Antimicrobial peptides containing unnatural amino acid exhibit potent bactericidal activity against ESKAPE pathogens

Hicks, R. P., Abercrombie, J. J., Wong, R. K. & Leung, K. P., Jan 1 2013, In : Bioorganic and Medicinal Chemistry. 21, 1, p. 205-214 10 p.

Research output: Contribution to journalArticle

Pathogens
Amino Acids
Peptides
Acids
Dipeptides
14 Citations (Scopus)

Antiproliferative Activity of Crocin Involves Targeting of Microtubules in Breast Cancer Cells

Hire, R. R., Srivastava, S., Davis, M. B., Kumar Konreddy, A. & Panda, D., Mar 24 2017, In : Scientific Reports. 7, 44984.

Research output: Contribution to journalArticle

Microtubules
Breast Neoplasms
Tubulin
Vinblastine
crocin
6 Citations (Scopus)

Antitumor activity of sulfated hyaluronic acid fragments in pre-clinical models of bladder cancer

Jordan, A. R., Lokeshwar, S. D., Lopez, L. E., Hennig, M., Chipollini, J., Yates, T., Hupe, M. C., Merseburger, A. S., Shiedlin, A., Cerwinka, W. H., Liu, K. & Lokeshwar, V. B., Jan 1 2017, In : Oncotarget. 8, 15, p. 24262-24274 13 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Urinary Bladder Neoplasms
Catenins
1-Phosphatidylinositol 4-Kinase
Neoplasms
42 Citations (Scopus)

A phase II evaluation of gefitinib in the treatment of persistent or recurrent endometrial cancer: A Gynecologic Oncology Group study

Leslie, K. K., Sill, M. W., Fischer, E., Darcy, K. M., Mannel, R. S., Tewari, K. S., Hanjani, P., Wilken, J. A., Baron, A. T., Godwin, A. K., Schilder, R. J., Singh, M. & Maihle, N. J., Jun 1 2013, In : Gynecologic Oncology. 129, 3, p. 486-494 9 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Epidermal Growth Factor Receptor
Extracellular Signal-Regulated MAP Kinases
Disease-Free Survival
Estrogen Receptors
22 Citations (Scopus)

Apoptosis in the skeletal muscle of untreated children with juvenile dermatomyositis: Impact of duration of untreated disease

Zhao, Y., Fedczyna, T. O., McVicker, V., Caliendo, J., Li, H. & Pachman, L. M., Nov 1 2007, In : Clinical Immunology. 125, 2, p. 165-172 8 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Muscle Weakness
In Situ Nick-End Labeling
Apoptosis
Caspase 3
206 Citations (Scopus)

Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6b

Huang, S., Jiang, Y., Li, Z., Nishida, E., Mathias, P., Lin, S., Ulevitch, R. J., Nemerow, G. R. & Han, J., Jan 1 1997, In : Immunity. 6, 6, p. 739-749 11 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase 6
Peptide Hydrolases
Apoptosis
T-Lymphocytes
Cell Death
118 Citations (Scopus)

Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine

Martin, P. M., El-sherbeny, A., Roon, P., Schoenlein, P. V., Ganapathy, V. & Smith, S. B., Jan 1 2001, In : Experimental Eye Research. 73, 1, p. 45-57 13 p.

Research output: Contribution to journalArticle

Excitatory Amino Acids
Retinal Ganglion Cells
Homocysteine
Cell Death
Ganglia
46 Citations (Scopus)

Application of 3D-QSAR for identification of descriptors defining bioactivity of antimicrobial peptides

Bhonsle, J. B., Venugopal, D., Huddler, D. P., Magill, A. J. & Hicks, R. P., Dec 27 2007, In : Journal of Medicinal Chemistry. 50, 26, p. 6545-6553 9 p.

Research output: Contribution to journalArticle

Quantitative Structure-Activity Relationship
Bioactivity
Peptides
Cell membranes
Mycobacterium
56 Citations (Scopus)

Application of a protein-blotting procedure to the study of human glucocorticoid receptor interactions with DNA

Silva, C. M., Tully, D. B., Petch, L. A., Jewell, C. M. & Cidlowski, J. A., Jun 11 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 7, p. 1744-1748 5 p.

Research output: Contribution to journalArticle

Glucocorticoid Receptors
Mouse mammary tumor virus
DNA
Proteins
Collodion

Application of measuring 99mTc-MAG3 plasma clearance based on one- compartment model (MPC method) to pediatric patients

Koizumi, K., Higashida, K., Arbab, A. S., Toyama, K., Arai, T. & Yoshitomi, T., Jun 26 1997, In : Kakuigaku. 34, 4, p. 259-265 7 p.

Research output: Contribution to journalArticle

Technetium Tc 99m Mertiatide
Pediatrics
Plasma Volume
Hematocrit
Body Weight
64 Citations (Scopus)

Applications of CpG island microarrays for high-throughput analysis of DNA methylation

Yan, P. S., Chen, C. M., Shi, H., Rahmatpanah, F., Wei, S. H. & Huang, T. H. M., Aug 15 2002, In : Journal of Nutrition. 132, 8 SUPPL., p. 2430S-2434S

Research output: Contribution to journalArticle

CpG Islands
DNA Methylation
Methylation
Glass
Clone Cells
6 Citations (Scopus)

A preliminary study of neopterin as a potential marker for severe dengue virus infection

Babb, K., Carrington, C. V. F. & Monteil, M. A., Jan 1 1999, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 93, 4, p. 447-448 2 p.

Research output: Contribution to journalArticle

Severe Dengue
Neopterin
Dengue Virus
Dengue
Virus Diseases
27 Citations (Scopus)

A preliminary study of serum concentrations of soluble epidermal growth factor receptor (sErbB1), gonadotropins, and steroid hormones in healthy men and women

Baron, A. T., Lafky, J. M., Maihle, N. J., Suman, V. J., Hillman, D. W., Buenafe, M. C., Boardman, C. H., Podratz, K. C. & Perez, E. A., Jan 1 2001, In : Cancer Epidemiology Biomarkers and Prevention. 10, 11, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

Gonadotropins
Epidermal Growth Factor Receptor
Steroids
Hormones
Serum
33 Citations (Scopus)

A randomized phase II study of sequential docetaxel and doxorubicin/cyclophosphamide in patients with metastatic breast cancer

Kugler, J. W., Perez, E. A., Geeraerts, L., Lafky, J. M., Ingle, J. N., Suman, V. J., Adjei, A. A., Baron, A. T., Hatfield, A. K., Maihle, N., Michalak, J. C. & Kuross, S. A., Aug 1 2002, In : Annals of Oncology. 13, 8, p. 1225-1235 11 p.

Research output: Contribution to journalArticle

docetaxel
Doxorubicin
Cyclophosphamide
Breast Neoplasms
Serum
2 Citations (Scopus)

Are cancer stem cells ready for prime time?

Liu, S., Korkaya, H. & Wicha, M. S., Apr 1 2012, In : Scientist. 26, 4

Research output: Contribution to journalArticle

23 Citations (Scopus)

A repressive epigenetic domino effect confers susceptibility to breast epithelial cell transformation: Implications for predicting breast cancer risk

Bistulfi, G., Pozzi, S., Ren, M., Rossetti, S. & Sacchi, N., Nov 1 2006, In : Cancer Research. 66, 21, p. 10308-10314 7 p.

Research output: Contribution to journalArticle

Cellular Retinol-Binding Proteins
Tretinoin
Epigenomics
Breast
Epithelial Cells
2 Citations (Scopus)

A retrospective analysis of invasive Streptococcus pneumoniae infections in Trinidad.

Williams, K. P. & Monteil, M. A., Mar 2000, In : The West Indian medical journal. 49, 1, p. 61-64 4 p.

Research output: Contribution to journalArticle

Trinidad and Tobago
Pneumococcal Infections
Pneumonia
Amoxicillin
Body Fluids
6 Citations (Scopus)

A retrospective study of the 1996 DEN-1 epidemic in Trinidad: Demographic and clinical features

Brown, T. U., Babb, K., Nimrod, M., Carrington, C. V. F., Salas, R. A. & Monteil, M. A., Dec 1 2004, In : Dengue Bulletin. 28, p. 7-19 13 p.

Research output: Contribution to journalArticle

Trinidad and Tobago
Islands
Dengue
Retrospective Studies
Demography
14 Citations (Scopus)

ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling

Davis, J. E., Xie, X., Guo, J., Huang, W., Chu, W. M., Huang, S., Teng, Y. & Wu, G., Jan 1 2016, In : Oncotarget. 7, 26, p. 39834-39845 12 p.

Research output: Contribution to journalArticle

ADP-Ribosylation Factor 1
Mitogen-Activated Protein Kinases
Prostate
Carcinogenesis
Prostatic Neoplasms
5 Citations (Scopus)

AR negative triple negative or “Quadruple Negative” breast cancers in African American women have an enriched basal and immune signature

Davis, M. B., Tripathi, S., Hughley, R., He, Q., Bae, S., Karanam, B., Martini, R., Newman, L., Colomb, W., Grizzle, W. & Yates, C., Jun 1 2018, In : PloS one. 13, 6, e0196909.

Research output: Contribution to journalArticle

Androgen Receptors
African Americans
breast neoplasms
Breast Neoplasms
Tumors
23 Citations (Scopus)

A role for cyclic-GMP dependent protein kinase in anoikis

Hou, Y., Wong, E., Martin, J., Schoenlein, P. V., Dostmann, W. R. & Browning, D. D., Jun 1 2006, In : Cellular Signalling. 18, 6, p. 882-888 7 p.

Research output: Contribution to journalArticle

Anoikis
Cyclic GMP-Dependent Protein Kinases
Suspensions
Apoptosis
Colon
117 Citations (Scopus)

A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

Samaddar, J. S., Gaddy, V. T., Duplantier, J., Thandavan, S. P., Shah, M., Smith, M. J., Browning, D., Rawson, J., Smith, S. B., Barrett, J. T. & Schoenlein, P. V., Oct 22 2008, In : Molecular cancer therapeutics. 7, 9, p. 2977-2987 11 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Autophagy
Cell Death
Breast Neoplasms
Caspases
15 Citations (Scopus)

ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates

Rajpurohit, S. K., Dec 1 2016, In : Nature Protocols. 11, 12, p. 2432-2453 22 p.

Research output: Contribution to journalArticle

Zebrafish
Drug Discovery
Screening
Throughput
Insulin

Article watch: December 2015

Slaughter, C. A., Dec 1 2015, In : Journal of Biomolecular Techniques. 26, 4, p. 150-156 7 p.

Research output: Contribution to journalArticle

Article watch: September 2015

Slaughter, C. A., Sep 1 2015, In : Journal of Biomolecular Techniques. 26, 3, p. 113-117 5 p.

Research output: Contribution to journalArticle

Article watch: September 2014

Slaughter, C. A., Sep 1 2014, In : Journal of Biomolecular Techniques. 25, 3, p. 87-91 5 p.

Research output: Contribution to journalArticle

Telefacsimile

Article watch, April 2011

Slaughter, C., Apr 1 2011, In : Journal of Biomolecular Techniques. 22, 1, p. 45-49 5 p.

Research output: Contribution to journalArticle

Article watch, July 2011

Slaughter, C., Jul 1 2012, In : Journal of Biomolecular Techniques. 22, 2, p. 86-89 4 p.

Research output: Contribution to journalArticle

Article watch, September 2011

Slaughter, C. A., Sep 1 2011, In : Journal of Biomolecular Techniques. 22, 3, p. 119-121 3 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A sandwich type acridinium-linked immunosorbent assay (ALISA) detects soluble ErbB1 (sErbB1) in normal human sera

Baron, A. T., Lafky, J. M., Connolly, D. C., Peoples, J., O'Kane, D. J., Suman, V. J., Boardman, C. H., Podratz, K. C. & Maihle, N. J., Oct 1 1998, In : Journal of Immunological Methods. 219, 1-2, p. 23-43 21 p.

Research output: Contribution to journalArticle

Immunosorbents
Serum
Body Fluids
Neoplasms
Tumor Biomarkers
30 Citations (Scopus)

Ascorbic and 6-Br-ascorbic acid conjugates as a tool to increase the therapeutic effects of potentially central active drugs

Dalpiaz, A., Pavan, B., Vertuani, S., Vitali, F., Scaglianti, M., Bortolotti, F., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Marzola, G., Prasad, P. D. & Manfredini, S., Jan 1 2005, In : European Journal of Pharmaceutical Sciences. 24, 4, p. 259-269 11 p.

Research output: Contribution to journalArticle

Therapeutic Uses
Ascorbic Acid
Retinal Pigment Epithelium
Pharmaceutical Preparations
Kynurenic Acid
8 Citations (Scopus)

A selective inhibitor of the UFM1-activating enzyme, UBA5

da Silva, S. R., Paiva, S. L., Bancerz, M., Geletu, M., Lewis, A. M., Chen, J., Cai, Y., Lukkarila, J. L., Li, H. & Gunning, P. T., Jan 1 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 18, p. 4542-4547 6 p.

Research output: Contribution to journalArticle

Ubiquitin
Cells
Cell Proliferation
Organometallics
Enzymes

A similar effect of P16 hydroxymethylation and true-methylation on the prediction of malignant transformation of oral epithelial dysplasia: Observation from a prospective study 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

Liu, H., Liu, Z., Liu, X. W., Xu, S., Wang, L., Liu, Y., Zhou, J., Gu, L., Gao, Y., Liu, X. Y., Shi, H., Sun, Z. & Deng, D., Sep 24 2018, In : BMC Cancer. 18, 1, 918.

Research output: Contribution to journalArticle

Methylation
Carcinogenesis
Observation
Prospective Studies
Health
5 Citations (Scopus)

A simplified cloning strategy for the generation of an endothelial cell selective recombinant adenovirus vector

Mahanivong, C., Krüger, J. A., Bian, D., Reisfeld, R. A. & Huang, S., Jul 1 2006, In : Journal of Virological Methods. 135, 1, p. 127-135 9 p.

Research output: Contribution to journalArticle

Adenoviridae
Organism Cloning
Endothelial Cells
NGR peptide
Genes
40 Citations (Scopus)

A single amino acid in the adenovirus type 37 fiber confers binding to human conjunctival cells

Huang, S., Reddy, V., Dasgupta, N. & Nemerow, G. R., Apr 1 1999, In : Journal of Virology. 73, 4, p. 2798-2802 5 p.

Research output: Contribution to journalArticle

Adenoviridae
serotypes
Amino Acids
amino acids
cells
80 Citations (Scopus)

A small-molecule inhibitor of MDMX activates p53 and induces apoptosis

Wang, H., Ma, X., Ren, S., Buolamwini, J. K. & Yan, C., Jan 1 2011, In : Molecular cancer therapeutics. 10, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

Apoptosis
Neoplasms
MCF-7 Cells
Preclinical Drug Evaluations
Cell Survival
32 Citations (Scopus)

A small-molecule p53 activato induces apoptosis through inhibiting MDMX expression in breast cancer cells1,2

Wang, H. & Yan, C., Jul 2011, In : Neoplasia. 13, 7, p. 611-619 9 p.

Research output: Contribution to journalArticle

(10-methyl-9-anthryl)methyl imidothiocarbamate
Apoptosis
Breast Neoplasms
pseudourea
Growth
5 Citations (Scopus)

Assessing heavy metal and PCB exposure from tap water by measuring levels in plasma from sporadic breast cancer patients, a pilot study

Zimeri, A. M., Robb, S. W., Hassan, S. M., Hire, R. R. & Davis, M. B., Dec 9 2015, In : International journal of environmental research and public health. 12, 12, p. 15683-15691 9 p.

Research output: Contribution to journalArticle

Polychlorinated Biphenyls
Heavy Metals
Breast Neoplasms
Water
Neoplasm Genes