Biochemistry and Molecular Biology

Article

CD4⁺CD25⁺ regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis

Singh, N., Yamamoto, M., Takami, M., Seki, Y., Takezaki, M., Mellor, A. L. & Iwashima, M., Jan 1 2010, In : Journal of Immunology. 184, 1, p. 94-104 11 p.

Research output: Contribution to journal › Article

19 Scopus citations

CD73 on cancer-associated fibroblasts enhanced by the A_2B-mediated feedforward circuit enforces an immune checkpoint

Yu, M., Guo, G., Huang, L., Deng, L., Chang, C. S., Achyut, B. R., Canning, M., Xu, N., Arbab, A. S., Bollag, R. J., Rodriguez, P. C., Mellor, A. L., Shi, H., Munn, D. H. & Cui, Y., Dec 1 2020, In : Nature communications. 11, 1, 515.

Research output: Contribution to journal › Article

Open Access

2 Scopus citations

CDDO-Me: A novel synthetic triterpenoid for the treatment of pancreatic cancer

Deeb, D., Gao, X., Arbab, A. S., Barton, K., Dulchavsky, S. A. & Gautam, S. C., Dec 1 2010, In : Cancers. 2, 4, p. 1779-1793 15 p.

Research output: Contribution to journal › Article

17 Scopus citations

cDNA cloning and functional analysis of the p97 subunit of the 265 proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11

Tsurumi, C., Shimizu, Y., Saeki, M., Kato, S., Demartino, G. N., Slaughter, C. A., Fujimuro, M., Yokosawa, H., Yamasaki, M. O., Hendil, K. B., Toh-E, A., Tanahashi, N. & Tanaka, K., Jan 1 1996, In : European Journal of Biochemistry. 239, 3, p. 912-921 10 p.

Research output: Contribution to journal › Article

55 Scopus citations

CDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family

Fujiwara, T., Watanabe, T. K., Tanaka, K., Slaughter, C. A. & DeMartino, G. N., Jun 3 1996, In : FEBS Letters. 387, 2-3, p. 184-188 5 p.

Research output: Contribution to journal › Article

23 Scopus citations

cDNA cloning of the bovine low density lipoprotein receptor: Feedback regulation of a receptor mRNA

Russell, D. W., Yamamoto, T., Schneider, W. J., Slaughter, C. A., Brown, M. S. & Goldstein, J. L., Jan 1 1983, In : Proceedings of the National Academy of Sciences of the United States of America. 80, 24 I, p. 7501-7505 5 p.

Research output: Contribution to journal › Article

83 Scopus citations

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

Wu, X., Prasad, P. D., Leibach, F. H. & Ganapathy, V., May 29 1998, In : Biochemical and Biophysical Research Communications. 246, 3, p. 589-595 7 p.

Research output: Contribution to journal › Article

296 Scopus citations

Cell growth and matrix invasion of EBV-immortalized human B lymphocytes is regulated by expression of α(v) integrins

Huang, S., Stupack, D., Liu, A., Cheresh, D. & Nemerow, G. R., Apr 6 2000, In : Oncogene. 19, 15, p. 1915-1923 9 p.

Research output: Contribution to journal › Article

32 Scopus citations

Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes

Bhagirath, D., Zhao, X., West, W. W., Qiu, F., Band, H. & Band, V., Jan 1 2015, In : Oncotarget. 6, 11, p. 9018-9030 13 p.

Research output: Contribution to journal › Article

Open Access

8 Scopus citations

Cell type-specific release of matrix-metallo-proteinase-9 by bacterial chemoattractant in human blood phagocytic leukocytes

Doerner, A. M., Chen, L. Y., Ye, R. D., Yong, J., Huang, S. & Pan, Z. K., Feb 22 2011, In : International Journal of Clinical and Experimental Medicine. 4, 1, p. 67-73 7 p.

Research output: Contribution to journal › Article

2 Scopus citations

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

Wu, C. H., Van Riggelen, J., Yetil, A., Fan, A. C., Bachireddy, P. & Felsher, D. W., Aug 7 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 32, p. 13028-13033 6 p.

Research output: Contribution to journal › Article

265 Scopus citations

Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity

Lingle, W. L., Lutz, W. H., Ingle, J. N., Maihle, N. J. & Salisbury, J. L., Mar 17 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 6, p. 2950-2955 6 p.

Research output: Contribution to journal › Article

403 Scopus citations

Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloidderived suppressor cells

Liu, F., Li, X., Lu, C., Bai, A., Bielawski, J., Bielawska, A., Marshall, B., Schoenlein, P. V., Lebedyeva, I. O. & Liu, K., Jan 1 2016, In : Oncotarget. 7, 51, p. 83907-83925 19 p.

Research output: Contribution to journal › Article

31 Scopus citations

Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes

Coe, G. L., Redd, P. S., Paschall, A. V., Lu, C., Gu, L., Cai, H., Albers, T., Lebedyeva, I. O. & Liu, K., Aug 4 2016, In : Scientific reports. 6, 30816.

Research output: Contribution to journal › Article

11 Scopus citations

Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression

Paschall, A. V., Zimmerman, M. A., Torres, C. M., Yang, D., Chen, M. R., Li, X., Bieberich, E., Bai, A., Bielawski, J., Bielawska, A. & Liu, K., Jan 15 2014, In : BMC Cancer. 14, 1, 24.

Research output: Contribution to journal › Article

37 Scopus citations

cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium

Wang, R., Islam, B. N., Bridges, A., Sharman, S. K., Hu, M., Hou, Y., Somanath, P. R., Venable, L., Singh, N., Kim, S., Sridhar, S., Hofmann, F. & Browning, D. D., Feb 1 2017, In : American Journal of Pathology. 187, 2, p. 377-389 13 p.

Research output: Contribution to journal › Article

8 Scopus citations

Changes in vascular permeability and expression of different angiogenic factors following anti-angiogenic treatment in rat glioma

Ali, M. M., Janic, B., Babajani-Feremi, A., Varma, N. R. S., Iskander, A. S. M., Anagli, J. & Arbab, A. S., Jan 15 2010, In : PloS one. 5, 1, e8727.

Research output: Contribution to journal › Article

52 Scopus citations

Chaperone-mediated autophagy degradation of IGF-1Rβ induced by NVP-AUY922 in pancreatic cancer

Xue, N., Lai, F., Du, T., Ji, M., Liu, D., Yan, C., Zhang, S., Yu, X., Jin, J. & Chen, X., Sep 1 2019, In : Cellular and Molecular Life Sciences. 76, 17, p. 3433-3447 15 p.

Research output: Contribution to journal › Article

2 Scopus citations

Characterization of [Re₂Cl₃(μ-dppm)₂(NCCH₃) ₂][Cl] and [Re₂Cl₃(μ-dppm)₂(NCC₆H ₅)₂][Cl] · 2CH₂Cl₂ by X-ray Crystallographic and Two-Dimensional NMR Spectroscopic Techniques

Concolino, T. E., Eglin, J. L., Hadden, C. E., Hicks, R. P., Staples, R. J., Valente, E. J. & Zubkowski, J. D., Jan 1 2000, In : Journal of Cluster Science. 11, 1, p. 109-123 15 p.

Research output: Contribution to journal › Article

1 Scopus citations

Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells

Prasad, P. D., Ramamoorthy, S., Leibach, F. H. & Ganapathy, V., Sep 10 1997, In : Placenta. 18, 7, p. 527-533 7 p.

Research output: Contribution to journal › Article

40 Scopus citations

Characterization of N ⁵-methyltetrahydrofolate uptake in cultured human retinal pigment epithelial cells

Huang, W., Prasad, P. D., Kekuda, R., Leibach, F. H. & Ganapathy, V., Aug 12 1997, In : Investigative Ophthalmology and Visual Science. 38, 8, p. 1578-1587 10 p.

Research output: Contribution to journal › Article

36 Scopus citations

Characterization of pressure-mediated vascular tone in resistance arteries from bile duct-ligated rats

Jadeja, R. N., Thounaojam, M. C. & Khurana, S., Jan 1 2017, In : Oncotarget. 8, 19, p. 30706-30722 17 p.

Research output: Contribution to journal › Article

3 Scopus citations

Characterization of progesterone receptor binding to the 90- and 70- kDa heat shock proteins

Schowalter, D. B., Sullivan, W. P., Maihle, N. J., Dobson, A. D. W., Conneely, O. M., O'Malley, B. W. & Toft, D. O., Jan 1 1991, In : Journal of Biological Chemistry. 266, 31, p. 21165-21173 9 p.

Research output: Contribution to journal › Article

62 Scopus citations

Characterization of the main phase transition in 1,2-dipalmitoyl-phosphatidylcholine LUVs by ¹H NMR

Kennedy, A., Hmel, P. J., Seelbaugh, J., Quiles, J. G., Hicks, R. & Reid, T. J., Dec 12 2002, In : Journal of Liposome Research. 12, 3, p. 221-237 17 p.

Research output: Contribution to journal › Article

13 Scopus citations

Characterization of the Moraxella catarrhalis uspA1 and uspA2 genes and their encoded products

Cope, L. D., Lafontaine, E. R., Slaughter, C. A., Hasemann, C. A., Aebi, C., Henderson, F. W., McCracken, G. H. & Hansen, E. J., Jul 1999, In : Journal of Bacteriology. 181, 13, p. 4026-4034 9 p.

Research output: Contribution to journal › Article

Open Access

87 Scopus citations

Chemoattractant-stimulated NF-κB Activation Is Dependent on the Low Molecular Weight GTPase RhoA

Huang, S., Chen, L. Y., Zuraw, B. L., Ye, R. D. & Pan, Z. K., Nov 2 2001, In : Journal of Biological Chemistry. 276, 44, p. 40977-40981 5 p.

Research output: Contribution to journal › Article

39 Scopus citations

Chemokine and chemokine receptor expression in kidney tumors: Molecular profiling of histological subtypes and association with metastasis

Gahan, J. C., Gosalbez, M., Yates, T., Young, E. E., Escudero, D. O., Chi, A., Garcia-Roig, M., Satyanarayana, R., Soloway, M. S., Bird, V. G. & Lokeshwar, V. B., Mar 1 2012, In : Journal of Urology. 187, 3, p. 827-833 7 p.

Research output: Contribution to journal › Article

28 Scopus citations

Chemotherapy rescues tumor-driven aberrant CD4⁺ T-cell differentiation and restores an activated polyfunctional helper phenotype

Ding, Z. C., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Mar 25 2010, In : Blood. 115, 12, p. 2397-2406 10 p.

Research output: Contribution to journal › Article

50 Scopus citations

Chimeric Mouse model to track the migration of bone marrow derived cells in glioblastoma following anti-angiogenic treatments

Achyut, B. R., Shankar, A., Iskander, A. S. M., Ara, R., Knight, R. A., Scicli, A. G. & Arbab, A. S., 2016, In : Cancer Biology and Therapy. 17, 3, p. 280-90 11 p.

Research output: Contribution to journal › Article

8 Scopus citations

Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer

Bhutia, Y. D., Ogura, J., Grippo, P. J., Torres, C., Sato, T., Wachtel, M., Ramachandran, S., Babu, E., Sivaprakasam, S., Rajasekaran, D., Schniers, B., On, N., Smoot, L., Thangaraju, M., Gnana-Prakasam, J. P. & Ganapathy, V., Mar 2020, In : Asian Journal of Pharmaceutical Sciences. 15, 2, p. 237-251 15 p.

Research output: Contribution to journal › Article

Open Access

2 Scopus citations

Chronic granulomatous disease 100% corrected by displacement bone marrow transplantation from a volunteer unrelated donor

Hobbs, J. R., Monteil, M., McCluskey, D. R., Jurges, E. & El Tumi, M., Nov 1 1992, In : European Journal of Pediatrics. 151, 11, p. 806-810 5 p.

Research output: Contribution to journal › Article

34 Scopus citations

Circadian clocks regulate adenylyl cyclase activity rhythms in human RPE cells

Pavan, B., Frigato, E., Pozzati, S., Prasad, P. D., Bertolucci, C. & Biondi, C., Nov 10 2006, In : Biochemical and Biophysical Research Communications. 350, 1, p. 169-173 5 p.

Research output: Contribution to journal › Article

19 Scopus citations

Circulating miR-583 and miR-663 Refer to ZHENG differentiation in chronic hepatitis B

Zhang, H., Guan, Y., Lu, Y. Y., Hu, Y. Y., Huang, S. & Su, S. B., Apr 29 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 751341.

Research output: Contribution to journal › Article

7 Scopus citations

Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway

Jiang, M., Wang, C. Y., Huang, S., Yang, T. & Dong, Z., May 1 2009, In : American Journal of Physiology - Renal Physiology. 296, 5, p. F983-F993

Research output: Contribution to journal › Article

71 Scopus citations

Cleavage of the retinal pigment epithelium-specific protein RPE65 under oxidative stress

Lee, H., Chung, H., Arnouk, H., Powell, F. L., Hunt, R. C., Hrushesky, W. J. M., Wood, P. A., Lee, S. H. & Jahng, W. J., Aug 1 2010, In : International Journal of Biological Macromolecules. 47, 2, p. 104-108 5 p.

Research output: Contribution to journal › Article

13 Scopus citations

Clerodendron glandulosum.Coleb extract ameliorates high fat diet/fatty acid induced lipotoxicity in experimental models of non-alcoholic steatohepatitis

Jadeja, R. N., Thounaojam, M. C., Dandekar, D. S., Devkar, R. V. & Ramachandran, A. V., Dec 1 2010, In : Food and Chemical Toxicology. 48, 12, p. 3424-3431 8 p.

Research output: Contribution to journal › Article

21 Scopus citations

Clerodendron glandulosum.Coleb extract prevents in vitro human LDL oxidation and oxidized LDL induced apoptosis in human monocyte derived macrophages

Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Ramachandran, A. V., Jun 1 2011, In : Food and Chemical Toxicology. 49, 6, p. 1195-1202 8 p.

Research output: Contribution to journal › Article

17 Scopus citations

Clerodendron glandulosum.Coleb leaf extract attenuates in vitro macrophage differentiation and expression of VCAM-1 and P-selectin in thoracic aorta of atherogenic diet fed rats

Jadeja, R. N., Thounaojam, M. C., Jain, M., Devkar, R. V. & Ramachandran, A. V., Jun 1 2012, In : Immunopharmacology and Immunotoxicology. 34, 3, p. 443-453 11 p.

Research output: Contribution to journal › Article

5 Scopus citations

Clerodendron glandulosum Coleb., Verbenaceae, melhora a dieta rica em gordura induzida por alteração no metabolismo de lipídios e colesterol em ratos

Translated title of the contribution: Clerodendron glandulosum Coleb., Verbenaceae, ameliorates high fat diet-induced alteration in lipid and cholesterol metabolism in ratsJadeja, R. N., Thounaojam, M. C., Ansarullah, Devkar, R. V. & Ramachandran, A. V., Jan 1 2010, In : Brazilian Journal of Pharmacognosy. 20, 1, p. 117-123 7 p.

Research output: Contribution to journal › Article

14 Scopus citations

Clerodendron glandulosum Coleb methanolic extract ameliorates high fat diet induced hyper lipidemia in male rats

Patel, D. K., Bhatt, R. K., Desai, S. N., Thounaojam, M. C., Jadeja, R. N., Ansarullah, Salunke, S. P., Padate, G. S., Devkar, R. V. & Ramachandran, A. V., Sep 17 2009, In : Pharmacologyonline. 2, p. 323-331 9 p.

Research output: Contribution to journal › Article

Climatic variables are associated with seasonal acute asthma admissions to accident and emergency room facilities in Trinidad, West Indies

Ivey, M. A., Simeon, D. T. & Monteil, M. A., Nov 1 2003, In : Clinical and Experimental Allergy. 33, 11, p. 1526-1530 5 p.

Research output: Contribution to journal › Article

37 Scopus citations

Clinical efficacy of modified preoperative neoadjuvant chemotherapy in the treatment of locally advanced (stage IB2 to IIB) ervical ancer: randomized study

Chen, H., Liang, C., Zhang, L., Huang, S. & Wu, X., Sep 1 2008, In : Gynecologic Oncology. 110, 3, p. 308-315 8 p.

Research output: Contribution to journal › Article

94 Scopus citations

Clinical Parameters Outperform Molecular Subtypes for Predicting Outcome in Bladder Cancer: Results from Multiple Cohorts, Including TCGA

Morera, D. S., Hasanali, S. L., Belew, D., Ghosh, S., Klaassen, Z., Jordan, A. R., Wang, J., Terris, M. K., Bollag, R. J., Merseburger, A. S., Stenzl, A., Soloway, M. S. & Lokeshwar, V. B., Jan 1 2020, In : The Journal of urology. 203, 1, p. 62-72 11 p.

Research output: Contribution to journal › Article

4 Scopus citations

Cloning and characterization of a potential-sensitive organic cation transporter (OCT3) from rat placenta

Kekuda, R., Prasad, P. D., Wu, X., Leibach, F. H. & Ganapathy, V., Mar 20 1998, In : FASEB Journal. 12, 5, p. A1043

Research output: Contribution to journal › Article

1 Scopus citations

Cloning and expression of a b^0,+-like amino acid transporter functioning asa heterodimer with 4F2hc-instead of rBAT. A new candidate gene for cystinuria

Rajan, D. P., Kekuda, R., Huang, W., Wang, H., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Oct 8 1999, In : Journal of Biological Chemistry. 274, 41, p. 29005-29010 6 p.

Research output: Contribution to journal › Article

59 Scopus citations

Cloning and functional characterization of a Na⁺-independent, broad-specific neutral amino acid transporter from mammalian intestine

Rajan, D. P., Kekuda, R., Huang, W., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jan 15 2000, In : Biochimica et Biophysica Acta - Biomembranes. 1463, 1, p. 6-14 9 p.

Research output: Contribution to journal › Article

75 Scopus citations

Cloning and functional characterization of a new subtype of the amino acid transport system N

Nakanishi, T., Kekuda, R., Fei, Y. J., Hatanaka, T., Sugawara, M., Martindale, R. G., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jan 1 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1757-C1768

Research output: Contribution to journal › Article

85 Scopus citations

Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta

Kekuda, R., Prasad, P. D., Wu, X., Wang, H., Fei, Y. J., Leibach, F. H. & Ganapathy, V., Jun 26 1998, In : Journal of Biological Chemistry. 273, 26, p. 15971-15979 9 p.

Research output: Contribution to journal › Article

360 Scopus citations

Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney

Gopal, E., Umapathy, N. S., Martin, P. M., Ananth, S., Gnana-Prakasam, J. P., Becker, H., Wagner, C. A., Ganapathy, V. & Prasad, P. D., Nov 1 2007, In : Biochimica et Biophysica Acta - Biomembranes. 1768, 11, p. 2690-2697 8 p.

Research output: Contribution to journal › Article

54 Scopus citations

Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types

Umapathy, N. S., Gnana-Prakasam, J. P., Martin, P. M., Mysona, B., Dun, Y., Smith, S. B., Ganapathy, V. & Prasad, P. D., Nov 1 2007, In : Investigative Ophthalmology and Visual Science. 48, 11, p. 5299-5305 7 p.

Research output: Contribution to journal › Article

45 Scopus citations