Biochemistry and Molecular Biology

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Cysteine redox sensor in PKGIα enables oxidant-induced activation

Burgoyne, J. R., Madhani, M., Cuello, F., Charles, R. L., Brennan, J. P., Schröder, E., Browning, D. D. & Eaton, P., Sep 7 2007, In : Science. 317, 5843, p. 1393-1397 5 p.

Research output: Contribution to journalArticle

330 Scopus citations

Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis

Liu, H. Y., Zheng, G., Treber, M., Dai, J. & Woldegiorgis, G., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 4524-4531 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer

Pejovic, T., Yates, J. E., Liu, H. Y., Hays, L. E., Akkari, Y., Torimaru, Y., Keeble, W., Rathbun, R. K., Rodgers, W. H., Bale, A. E., Ameziane, N., Zwaan, C. M., Errami, A., Thuillier, P., Cappuccini, F., Olson, S. B., Cain, J. M. & Bagby, G. C., Sep 15 2006, In : Cancer Research. 66, 18, p. 9017-9025 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In : International journal of molecular sciences. 19, 2, 577.

Research output: Contribution to journalArticle

2 Scopus citations

Cytokine gene polymorphisms and the pathology of chronic gastritis

Moorchung, N., Srivastava, A. N., Gupta, N. K., Ghoshal, U. C., Achyut, B. R. & Mittal, B., May 2007, In : Singapore Medical Journal. 48, 5, p. 447-54 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Cytotoxicity evaluation and antimicrobial studies of starch capped water soluble copper nanoparticles

Valodkar, M., Rathore, P. S., Jadeja, R. N., Thounaojam, M., Devkar, R. V. & Thakore, S., Jan 30 2012, In : Journal of Hazardous Materials. 201-202, p. 244-249 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Cytotoxicity evaluation and hepatoprotective potential of bioassay guided fractions from Feronia limmonia Linn leaf

Jain, M., Kapadia, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Mishra, S. H., Dec 2011, In : Asian Pacific Journal of Tropical Biomedicine. 1, 6, p. 443-447 5 p.

Research output: Contribution to journalArticle

37 Scopus citations
Open Access

Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Jadeja, R. N., Urrunaga, N. H., Ahmad, D. & Khurana, S., Mar 1 2016, In : Data in Brief. 6, p. 405-409 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Death of retinal neurons in streptozotocin-induced diabetic mice

Martin, P. M., Roon, P., Van Ells, T. K., Ganapathy, V. & Smith, S. B., Sep 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 9, p. 3330-3336 7 p.

Research output: Contribution to journalArticle

324 Scopus citations

Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to fas ligand-induced apoptosis in vitro and tumor suppression in vivo

Yang, D., Torres, C. M., Bardhan, K., Zimmerman, M., McGaha, T. L. & Liu, K., May 1 2012, In : Journal of Immunology. 188, 9, p. 4441-4449 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Defective antibody-mediated opsonisation of S. pneumoniae in high risk patients detected by flow cytometry

Obaro, S. K., Henderson, D. C. & Monteil, M. A., Jan 1996, In : Immunology Letters. 49, 1-2, p. 83-89 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Defective T-cell receptor-induced apoptosis of T cells and rejection of transplanted immunogenic tumors in p53-/- mice

Singh, N., Huang, L. & Qin, H., Feb 1 2010, In : European Journal of Immunology. 40, 2, p. 559-568 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study

Khodaverdian, V., Tapadar, S., MacDonald, I. A., Xu, Y., Ho, P. Y., Bridges, A., Rajpurohit, P., Sanghani, B. A., Fan, Y., Thangaraju, M., Hathaway, N. A. & Oyelere, A. K., Dec 1 2019, In : Scientific reports. 9, 1, 4802.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock

Subramani, K., Chu, X., Warren, M., Lee, M., Lu, S., Singh, N. & Raju, R. P., Mar 1 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 3, p. 688-695 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Degradation of Oxidized Insulin B Chain by the Multiproteinase Complex Macropain (Proteasome)

Dick, L. R., Moomaw, C. R., DeMartino, G. N. & Slaughter, C. A., Mar 1 1991, In : Biochemistry. 30, 10, p. 2725-2734 10 p.

Research output: Contribution to journalArticle

82 Scopus citations
8 Scopus citations

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

Hong, Y., Manoharan, I., Suryawanshi, A., Shanmugam, A., Swafford, D., Ahmad, S., Chinnadurai, R., Manicassamy, B., He, Y., Mellor, A. L., Thangaraju, M., Munn, D. H. & Manicassamy, S., Apr 2 2016, In : OncoImmunology. 5, 4

Research output: Contribution to journalArticle

24 Scopus citations

Deletion of the amino acid transporter SLC6A14 suppresses tumour growth in spontaneous mouse models of breast cancer

Babu, E., Bhutia, Y. D., Ramachandran, S., Gnana-Prakasam, J. P., Prasad, P. D., Thangaraju, M. & Ganapathy, V., Jul 1 2015, In : Biochemical Journal. 469, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

De novo design of selective antibiotic peptides by incorporation of unnatural amino acids

Hicks, R. P., Bhonsle, J. B., Venugopal, D., Koser, B. W. & Magill, A. J., Jun 28 2007, In : Journal of Medicinal Chemistry. 50, 13, p. 3026-3036 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

De novo transcriptome sequencing in a songbird, the dark-eyed junco (Junco hyemalis): genomic tools for an ecological model system

Peterson, M. P., Whittaker, D. J., Ambreth, S., Sureshchandra, S., Buechlein, A., Podicheti, R., Choi, J. H., Lai, Z., Mockatis, K., Colbourne, J., Tang, H. & Ketterson, E. D., Jul 9 2012, In : BMC Genomics. 13, 1, 305.

Research output: Contribution to journalArticle

27 Scopus citations

Derangement of a factor upstream of RARalpha triggers the repression of a pleiotropic epigenetic network.

Corlazzoli, F., Rossetti, S., Bistulfi, G., Ren, M. & Sacchi, N., Jan 1 2009, In : PLoS One. 4, 1

Research output: Contribution to journalArticle

17 Scopus citations

Deregulation of apoptotic factors Bcl-xL and Bax confers apoptotic resistance to myeloid-derived suppressor cells and contributes to their persistence in cancer

Hu, X., Bardhan, K., Paschall, A. V., Yang, D., Waller, J. L., Park, M. A., Nayak, A., Samuel, T. A., Abrams, S. I. & Liu, K., Jun 28 2013, In : Journal of Biological Chemistry. 288, 26, p. 19103-19115 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

Descriptive epidemiology of asthma in Trinidad, West Indies

Monteil, M. A., Juman, S., Hassanally, R., Williams, K. P., Pierre, L., Rahaman, M., Singh, H. & Trinidade, A., Jan 1 2000, In : Journal of Asthma. 37, 8, p. 677-684 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity

Manfredini, S., Pavan, B., Vertuani, S., Scaglianti, M., Compagnone, D., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Prasad, P. D. & Dalpiaz, A., Jan 31 2002, In : Journal of Medicinal Chemistry. 45, 3, p. 559-562 4 p.

Research output: Contribution to journalArticle

85 Scopus citations

Design, synthesis and biological activities of quinazoline containing sorafenib analogs as antitumor agents

Zhang, J., Wang, N., Xie, X., Yan, C., Fu, F., Yao, J. & Wang, H., Jun 1 2017, In : Wuhan University Journal of Natural Sciences. 22, 3, p. 239-246 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules

Manfredini, S., Vertuani, S., Pavan, B., Vitali, F., Scaglianti, M., Bortolotti, F., Biondi, C., Scatturin, A., Prasad, P. & Dalpiaz, A., Oct 15 2004, In : Bioorganic and Medicinal Chemistry. 12, 20, p. 5453-5463 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Detection of differentially methylated regions using bayes factor for ordinal group responses

Dunbar, F., Xu, H., Ryu, D., Ghosh, S., Shi, H. & George, V., Sep 2019, In : Genes. 10, 9, 721.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Detection of lung and chest tumours using99tcm-tetrofosmin comparison with 201t1

Arbab, A. S., Toyama, K., Arak, T., Araki, T. & Koizumi, K., Jul 1998, In : Nuclear Medicine Communications. 19, 7, 1 p.

Research output: Contribution to journalArticle

8 Scopus citations

Determinants of Gli2 co-activation of wildtype and naturally truncated androgen receptors

Li, N., Chen, M., Truong, S., Yan, C. & Buttyan, R., Oct 2014, In : Prostate. 74, 14, p. 1400-1410 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Determining the effect of the incorporation of unnatural amino acids into antimicrobial peptides on the interactions with zwitterionic and anionic membrane model systems

Russell, A. L., Kennedy, A. M., Spuches, A. M., Gibson, W. S., Venugopal, D., Klapper, D., Srouji, A. H., Bhonsle, J. B. & Hicks, R. P., Nov 1 2011, In : Chemistry and Physics of Lipids. 164, 8, p. 740-758 19 p.

Research output: Contribution to journalArticle

13 Scopus citations

Development of a novel animal model to differentiate radiation necrosis from tumor recurrence

Kumar, S., Arbab, A. S., Jain, R., Kim, J., DeCarvalho, A. C., Shankar, A., Mikkelsen, T. & Brown, S. L., Jul 2012, In : Journal of Neuro-Oncology. 108, 3, p. 411-420 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Development of a partial fibronectin knockout transgenic mouse model

Manshouri, T., Huang, S., Sundaresan, A., Chakravarthy, M., Chakrabarty, S. & Albitar, M., Jan 1 1997, In : Transgenics. 2, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

Development of ZMYM2-FGFR1 driven AML in human CD34+ cells in immunocompromised mice

Ren, M., Qin, H., Wu, Q., Savage, N. M., George, T. I. & Cowell, J. K., Aug 15 2016, In : International Journal of Cancer. 139, 4, p. 836-840 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Diagnosis and characterization of acute erythroleukemia subsets by determining the percentages of myeloblasts and proerythroblasts in 69 cases

Ramchandran, R., Bengra, C., Whitney, B., Lanclos, K. & Tuan Lo, D., Sep 11 2000, In : American Journal of Hematology. 65, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: A RPE specific phenomenon

Ananth, S., Zhuang, L., Gopal, E., Itagaki, S., Ellappan, B., Smith, S. B., Ganapathy, V. & Martin, P., Mar 26 2010, In : Biochemical and Biophysical Research Communications. 394, 1, p. 75-80 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
29 Scopus citations

Dietary Supplement 4-Methylumbelliferone: An Effective Chemopreventive and Therapeutic Agent for Prostate Cancer

Yates, T. J., Lopez, L. E., Lokeshwar, S. D., Ortiz, N., Kallifatidis, G., Jordan, A., Hoye, K., Altman, N. & Lokeshwar, V. B., Jul 1 2015, In : Journal of the National Cancer Institute. 107, 7, djv085.

Research output: Contribution to journalArticle

38 Scopus citations

Diet-induced obesity and mammary tumor development in MMTV-neu female mice

Cleary, M. P., Grande, J. P., Juneja, S. C. & Maihle, N. J., Dec 1 2004, In : Nutrition and Cancer. 50, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer

Yan, P. S., Shi, H., Rahmatpanah, F., Hsiau, T. H. C., Hsiau, A. H. A., Leu, Y. W., Liu, J. C. & Huang, T. H. M., Oct 1 2003, In : Cancer Research. 63, 19, p. 6178-6186 9 p.

Research output: Contribution to journalArticle

103 Scopus citations

Differential influence of the 4F2 heavy chain and the protein related to b0,+ amino acid transport on substrate affinity of the heteromeric b0,+ amino acid transporter

Rajan, D. P., Huang, W., Kekuda, R., George, R. L., Wang, J., Conway, S. J., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., May 12 2000, In : Journal of Biological Chemistry. 275, 19, p. 14331-14335 5 p.

Research output: Contribution to journalArticle

44 Scopus citations
Open Access
3 Scopus citations

Differential methylation tests of regulatory regions

Ryu, D., Xu, H., George, V., Su, S., Wang, X., Shi, H. & Podolsky, R. H., Jun 1 2016, In : Statistical Applications in Genetics and Molecular Biology. 15, 3, p. 237-251 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinases

Bell, S. M., Connolly, D. C., Maihle, N. J. & Degen, J. L., Sep 1993, In : Molecular and Cellular Biology. 13, 9, p. 5888-5897 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Differential modulation of sodium- and chloride-dependent opioid peptide transport system by small nonopioid peptides and free amino acids

Miyauchi, S., Gopal, E., Thakkar, S. V., Ichikawa, S., Prasad, P. D. & Ganapathy, V., Apr 1 2007, In : Journal of Pharmacology and Experimental Therapeutics. 321, 1, p. 257-264 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Differential PI3Kδ signaling in CD4+ T-cell subsets enables selective targeting of t regulatory cells to enhance cancer immunotherapy

Ahmad, S., Abu-Eid, R., Shrimali, R. K., Webb, M., Verma, V., Doroodchi, A., Berrong, Z., Samara, R., Rodriguez, P. C., Mkrtichyan, M. & Khleif, S. N., Apr 15 2017, In : Cancer Research. 77, 8, p. 1892-1904 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Differential recognition of β-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2

Ganapathy, M. E., Brandsch, M., Prasad, P. D., Ganapathy, V. & Leibach, F. H., Jan 1 1995, In : Journal of Biological Chemistry. 270, 43, p. 25672-25677 6 p.

Research output: Contribution to journalArticle

246 Scopus citations

Differential regulation of cell motility and invasion by FAK

Hsia, D. A., Mitra, S. K., Hauck, C. R., Streblow, D. N., Nelson, J. A., Ilic, D., Huang, S., Li, E., Nemerow, G. R., Leng, J., Spencer, K. S. R., Cheresh, D. A. & Schlaepfer, D. D., Mar 3 2003, In : Journal of Cell Biology. 160, 5, p. 753-767 15 p.

Research output: Contribution to journalArticle

422 Scopus citations

Direct detection by 15N NMR of the tryptophan tryptophylquinone aminoquinol reaction intermediate of methylamine dehydrogenase

Bishop, G. R., Valente, E. J., Whitehead, T. L., Brown, K. L., Hicks, R. P. & Davidson, V. L., Dec 1 1996, In : Journal of the American Chemical Society. 118, 50, p. 12868-12869 2 p.

Research output: Contribution to journalArticle

30 Scopus citations