Biochemistry and Molecular Biology

Research Output 1968 2019

Filter
Article
Article

[125 I]IodoDPA-713 binding to 18 kDa translocator protein (TSPO) in a mouse model of intracerebral hemorrhage: Implications for neuroimaging

Bonsack, F., Foss, C. A., Arbab, A. S., Alleyne, C. H., Pomper, M. G. & Sukumari-Ramesh, S., Feb 22 2018, In : Frontiers in Neuroscience. 12, FEB, 66.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Neuroimaging
Proteins
Brain
Autoradiography

[Biological effects of sCD40L on acute myeloid leukemia cells HL-60 and its mechanism].

Li, J., Chen, Q. & Ren, M., Apr 1 2012, In : Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 33, 4, p. 324-326 3 p.

Research output: Contribution to journalArticle

CD95 Antigens
CD40 Ligand
HL-60 Cells
Myeloid Cells
Acute Myeloid Leukemia
46 Citations (Scopus)

1,3,8-Trisubstituted Xanthines. Effects of Substitution Pattern upon Adenosine Receptor A1/A2 Affinity

Erickson, R. H., Hiner, R. N., Feeney, S. W., Blake, P. R., Rzeszotarski, W. J., Hicks, R. P., Costello, D. G. & Abreu, M. E., Apr 1 1991, In : Journal of Medicinal Chemistry. 34, 4, p. 1431-1435 5 p.

Research output: Contribution to journalArticle

Xanthines
Adenosine A2 Receptors
Adenosine A1 Receptors
varespladib methyl
21 Citations (Scopus)

53BP1 promotes microhomology-mediated end-joining in G1-phase cells

Xiong, X., Du, Z., Wang, Y., Feng, Z., Fan, P., Yan, C., Willers, H. & Zhang, J., Jan 1 2015, In : Nucleic Acids Research. 43, 3, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

G1 Phase
Double-Stranded DNA Breaks
Sequence Deletion
Genomic Instability
Homologous Recombination
6 Citations (Scopus)

5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation

Wang, J., Peng, L., Zhang, R., Zheng, Z., Chen, C., Cheung, K. L., Cui, M., Bian, G., Xu, F., Chiang, D., Hu, Y., Chen, Y., Lu, G., Yang, J., Zhang, H., Yang, J., Zhu, H., Chen, S. H., Liu, K., Zhou, M. M. & 4 others, Sikora, A. G., Li, L., Jiang, B. & Xiong, H., Apr 12 2016, In : Oncotarget. 7, 15, p. 19312-19326 15 p.

Research output: Contribution to journalArticle

Th17 Cells
Thymidylate Synthase
Fluorouracil
Cell Differentiation
Colitis

89Sr therapy for pain relief in patients with bone metastases

Koizumi, K., Arbab, A. S., Toyama, K., Shirasu, M., Osawa, S., Araki, T., Yamaguchi, M., Onishi, H., Araki, T., Arai, T., Komatsu, H., Ueno, A. & Nokata, H., Dec 1 1996, In : Kakuigaku. 33, 11, p. 1243-1248 6 p.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Bone and Bones
Pain
Therapeutics
Bone Marrow
17 Citations (Scopus)

A (GATA)7 motif located in the 5' boundary area of the human β-globin locus control region exhibits silencer activity in erythroid cells

Ramchandran, R., Bengra, C., Whitney, B., Lanclos, K. & Tuan Lo, D., Jan 1 2000, In : American Journal of Hematology. 65, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

Locus Control Region
Phosphoglycerate Kinase
Erythroid Cells
Chloramphenicol O-Acetyltransferase
Globins
66 Citations (Scopus)

A 1.8 kb alternative transcript from the human epidermal growth factor receptor gene encodes a truncated form of the receptor

Reiter, J. L. & Maihle, N. J., Nov 28 1996, In : Nucleic Acids Research. 24, 20, p. 4050-4056 7 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Epidermal Growth Factor Receptor
Complementary DNA
Ligands
RNA Splice Sites
62 Citations (Scopus)

A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease

Zhou, J., Wu, R., High, A. A., Slaughter, C. A., Finkelstein, D., Rehg, J. E., Redecke, V. & Häcker, H., Nov 1 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 44, p. E998-E1006

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
Toll-Like Receptors
Nitric Oxide Synthase Type II
Inflammation
Anti-Inflammatory Agents
427 Citations (Scopus)

A2A adenosine receptor protects tumors from antitumor T cells

Ohta, A., Gorelik, E., Prasad, S. J., Ronchese, F., Lukashev, D., Wong, M. K. K., Huang, X., Caldwell, S., Liu, K., Smith, P., Chen, J. F., Jackson, E. K., Apasov, S., Abrams, S. & Sitkovsky, M., Aug 29 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 35, p. 13132-13137 6 p.

Research output: Contribution to journalArticle

Adenosine A2A Receptors
T-Lymphocytes
Neoplasms
Tumor Microenvironment
Autoimmunity
60 Citations (Scopus)

A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37

Wu, E., Fernandez, J., Fleck, S. K., Von Seggern, D. J., Huang, S. & Nemerow, G. R., Jan 20 2001, In : Virology. 279, 1, p. 78-89 12 p.

Research output: Contribution to journalArticle

N-Acetylneuraminic Acid
Adenoviridae
Membrane Proteins
Infection
Enterovirus
3 Citations (Scopus)
Diketopiperazines
disulfides
Proline
routes
activation
19 Citations (Scopus)

Aberrant Epigenetic Gene Regulation in Lymphoid Malignancies

Taylor, K. H., Briley, A., Wang, Z., Cheng, J., Shi, H. & Caldwell, C. W., Jan 1 2013, In : Seminars in Hematology. 50, 1, p. 38-47 10 p.

Research output: Contribution to journalArticle

Epigenomics
DNA Packaging
Non-Hodgkin's Lymphoma
Genes
Neoplasms
25 Citations (Scopus)
Nutrition
Ablation
Energy Metabolism
Insulin Resistance
Insulin
19 Citations (Scopus)

A brief overview of antimicrobial peptides containing unnatural amino acids and Ligand-based approaches for peptide Ligands

Bhonsle, J. B., Clark, T., Bartolotti, L. & Hicks, R. P., Jan 1 2013, In : Current Topics in Medicinal Chemistry. 13, 24, p. 3205-3224 20 p.

Research output: Contribution to journalArticle

Ligands
Amino Acids
Peptides
Calorimetry
Circular Dichroism
34 Citations (Scopus)

Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: Role of cystine/glutamate exchanger

Gnana-Prakasam, J. P., Thangaraju, M., Liu, K., Ha, Y., Martin, P. M., Smith, S. B. & Ganapathy, V., Dec 1 2009, In : Biochemical Journal. 424, 2, p. 243-252 10 p.

Research output: Contribution to journalArticle

Iron-Regulatory Proteins
Retinal Pigments
Cystine
Retinal Pigment Epithelium
Glutamic Acid
20 Citations (Scopus)

A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes

Bayoumi, A. S., Park, K. M., Wang, Y., Teoh, J. P., Aonuma, T., Tang, Y. L., Su, H., Weintraub, N. L. & Kim, I., Jan 1 2018, In : Journal of molecular and cellular cardiology. 114, p. 72-82 11 p.

Research output: Contribution to journalArticle

MicroRNAs
Cardiac Myocytes
Myocardial Infarction
Adrenergic Receptors
Apoptosis
36 Citations (Scopus)

A chromosomal region 7p11.2 transcript map: Its development and application to the study of EGFR amplicons in glioblastoma

Eley, G. D., Reiter, J. L., Pandita, A., Park, S., Jenkins, R. B., Maihle, N. J. & James, C. D., Jan 1 2002, In : Neuro-Oncology. 4, 2, p. 86-94 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Epidermal Growth Factor Receptor
P1 Bacteriophage Artificial Chromosomes
Radiation Hybrid Mapping
Chromosomes
318 Citations (Scopus)

A cis-regulatory map of the Drosophila genome

Négre, N., Brown, C. D., Ma, L., Bristow, C. A., Miller, S. W., Wagner, U., Kheradpour, P., Eaton, M. L., Loriaux, P., Sealfon, R., Li, Z., Ishii, H., Spokony, R. F., Chen, J., Hwang, L., Cheng, C., Auburn, R. P., Davis, M. B., Domanus, M., Shah, P. K. & 20 others, Morrison, C. A., Zieba, J., Suchy, S., Senderowicz, L., Victorsen, A., Bild, N. A., Grundstad, A. J., Hanley, D., MacAlpine, D. M., Mannervik, M., Venken, K., Bellen, H., White, R., Gerstein, M., Russell, S., Grossman, R. L., Ren, B., Posakony, J. W., Kellis, M. & White, K. P., Mar 24 2011, In : Nature. 471, 7339, p. 527-531 5 p.

Research output: Contribution to journalArticle

Drosophila
Transcription Factors
Chromatin
Genome
Binding Sites
30 Citations (Scopus)

Aconitase polymorphism in man

SLAUGHTER, C. A., HOPKINSON, D. A. & HARRIS, HARRY., Oct 1975, In : Annals of Human Genetics. 39, 2, p. 193-202 10 p.

Research output: Contribution to journalArticle

Aconitate Hydratase
Isoenzymes
Alleles
Population
Phenotype
44 Citations (Scopus)

A conserved sequence element in ribonuclease III processing signals is not required for accurate in vitro enzymatic cleavage

Chelladurai, B. S., Li, H. & Nicholson, A. W., Apr 25 1991, In : Nucleic Acids Research. 19, 8, p. 1759-1766 8 p.

Research output: Contribution to journalArticle

Ribonuclease III
Conserved Sequence
RNA
Base Pairing
RNA Phages
10 Citations (Scopus)

A critical role of CXCR2 PDZ-mediated interactions in endothelial progenitor cell homing and angiogenesis

Hou, Y., Wu, Y., Farooq, S. M., Guan, X., Wang, S., Liu, Y., Oblak, J. J., Holcomb, J., Jiang, Y., Strieter, R. M., Lasley, R. D., Arbab, A. S., Sun, F., Li, C. & Yang, Z., Mar 1 2015, In : Stem Cell Research. 14, 2, p. 133-143 11 p.

Research output: Contribution to journalArticle

Macromolecular Substances
Endothelial Progenitor Cells
Chemokine Receptors
Chemokines
Cell Movement
137 Citations (Scopus)

Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination

Yan, C., Lu, D., Hai, T. & Boyd, D. D., Jul 6 2005, In : EMBO Journal. 24, 13, p. 2425-2435 11 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
Ubiquitination
Sensors
DNA Damage
Null Lymphocytes
39 Citations (Scopus)

Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6

Wang, H., Mo, P., Ren, S. & Yan, C., Apr 23 2010, In : Journal of Biological Chemistry. 285, 17, p. 13201-13210 10 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
Protein Binding
Uterine Cervical Neoplasms
Proteins
Ubiquitin
73 Citations (Scopus)

Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B

Shi, L., Chen, G., Macdonald, G., Bergeron, L., Li, H., Miura, M., Rotello, R. J., Miller, D. K., Li, P., Seshadri, T., Yuan, J. & Greenberg, A. H., Oct 1 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 20, p. 11002-11007 6 p.

Research output: Contribution to journalArticle

Granzymes
Caspase 1
Apoptosis
Peptide Hydrolases
Cytotoxic T-Lymphocytes
24 Citations (Scopus)

Activation of cGMP-dependent protein kinase by protein kinase C

Hou, Y., Lascola, J., Dulin, N. O., Ye, R. D. & Browning, D. D., May 9 2003, In : Journal of Biological Chemistry. 278, 19, p. 16706-16712 7 p.

Research output: Contribution to journalArticle

Cyclic GMP-Dependent Protein Kinases
Phosphorylation
Protein Kinase C
Chemical activation
Signal transduction
573 Citations (Scopus)

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., Lee, J. R., Offermanns, S. & Ganapathy, V., Jan 16 2014, In : Immunity. 40, 1, p. 128-139 12 p.

Research output: Contribution to journalArticle

Butyrates
Niacin
Colonic Neoplasms
Carcinogenesis
Inflammation
54 Citations (Scopus)
Phosphorylation
p38 Mitogen-Activated Protein Kinases
Lipopolysaccharides
Nitric Oxide
Neutrophils
25 Citations (Scopus)

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R. W., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journalArticle

Antigen-Presenting Cells
Myeloid Cells
Immunotherapy
Cell Differentiation
Cross-Priming
26 Citations (Scopus)

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., Feb 1 2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

RNA Precursors
Phosphorylation
Serine
Exons
Protein Splicing
71 Citations (Scopus)
Matrix Metalloproteinase 13
Cyclic GMP-Dependent Protein Kinases
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinases
34 Citations (Scopus)

Activation of the small GTPase Rac1 by cGMP-dependent protein kinase

Hou, Y., Ye, R. D. & Browning, D. D., Jan 1 2004, In : Cellular Signalling. 16, 9, p. 1061-1069 9 p.

Research output: Contribution to journalArticle

Cyclic GMP-Dependent Protein Kinases
Monomeric GTP-Binding Proteins
p38 Mitogen-Activated Protein Kinases
HEK293 Cells
Transfection
26 Citations (Scopus)

Acute Depletion Redefines the Division of Labor among DNA Methyltransferases in Methylating the Human Genome

Tiedemann, R. L., Putiri, E. L., Lee, J. H., Hlady, R. A., Kashiwagi, K., Ordog, T., Zhang, Z., Liu, C., Choi, J-H. & Robertson, K. D., Nov 20 2014, In : Cell Reports. 9, 4, p. 1554-1566 13 p.

Research output: Contribution to journalArticle

Methylation
Methyltransferases
Human Genome
Genes
Personnel
16 Citations (Scopus)
Myeloproliferative Disorders
B-Lymphoid Precursor Cells
B-lymphocytes
lymphoma
leukemia
63 Citations (Scopus)

Acylation of the lymphoma transmembrane glycoprotein, GP85, may be required for GP85-ankyrin interaction

Bourguignon, L. Y. W., Kalomiris, E. L. & Lokeshwar, V. B., Nov 5 1991, In : Journal of Biological Chemistry. 266, 18, p. 11761-11765 5 p.

Research output: Contribution to journalArticle

Ankyrins
Acylation
Palmitic Acid
Lymphoma
Glycoproteins
14 Citations (Scopus)

Adenovirus E1A oncoprotein liberates c-Myc activity to promote cell proliferation through abating Bin1 expression via an Rb/E2F1-dependent mechanism

Kinney, E. L., Tanida, S., Rodrigue, A. A., Johnson, J. K., Tompkins, V. S. & Sakamuro, D., Sep 1 2008, In : Journal of Cellular Physiology. 216, 3, p. 621-631 11 p.

Research output: Contribution to journalArticle

Oncogene Proteins
Cell proliferation
Fibroblasts
Adenoviridae
Small Interfering RNA
207 Citations (Scopus)

Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells

Huang, S., Kamata, T., Takada, Y., Ruggeri, Z. M. & Nemerow, G. R., Jun 27 1996, In : Journal of Virology. 70, 7, p. 4502-4508 7 p.

Research output: Contribution to journalArticle

integrins
Adenoviridae
gene transfer
Integrins
Genes
146 Citations (Scopus)

Adenovirus internalization and infection require dynamin

Wang, K., Huang, S., Kapoor-Munshi, A. & Nemerow, G., Apr 1 1998, In : Journal of Virology. 72, 4, p. 3455-3458 4 p.

Research output: Contribution to journalArticle

Dynamins
Adenoviridae Infections
Virus Internalization
Clathrin
Adenoviridae
96 Citations (Scopus)

Adenovirus vector pseudotyping in fiber-expressing cell lines: Improved transduction of Epstein-Barr virus-transformed B cells

Von Seggern, D. J., Huang, S., Fleck, S. K., Stevenson, S. C. & Nemerow, G. R., Jan 1 2000, In : Journal of Virology. 74, 1, p. 354-362 9 p.

Research output: Contribution to journalArticle

Human herpesvirus 4
fiber cells
Adenoviridae
Human Herpesvirus 4
B-lymphocytes
1 Citation (Scopus)

Adenylate kinase and aconitase in human rodent somatic cell hybrids

Povey, S., Slaughter, C. A., Wilson, D. E., Buckton, K., Gormley, I. P. & Perry, P., Dec 1 1976, In : Cytogenetics and Cell Genetics. 16, 1-5, p. 211-214 4 p.

Research output: Contribution to journalArticle

Chromosomes, Human, 6-12 and X
Aconitate Hydratase
Hydro-Lyases
Adenylate Kinase
Hybrid Cells
1 Citation (Scopus)

Adenylate kinase and aconitase in human rodent somatic cell hybrids HUMAN GENE MAPPING.3.

Povey, S., Slaughter, C. A., Wilson, D. E., Buckton, K., Gormley, I. P. & Perry, P., Dec 1 1976, In : Birth Defects: Original Article Series. 12, 7, p. 211-214 4 p.

Research output: Contribution to journalArticle

Chromosomes, Human, 6-12 and X
Aconitate Hydratase
Hydro-Lyases
Adenylate Kinase
Hybrid Cells
208 Citations (Scopus)

Adhesion-induced tyrosine phosphorylation of the p130 SRC substrate

Petch Lee, L. A., Bockholt, S. M., Bouton, A., Parsons, J. T. & Burridge, K., Jan 1 1995, In : Journal of Cell Science. 108, 4, p. 1371-1379 9 p.

Research output: Contribution to journalArticle

Tyrosine
Phosphorylation
Paxillin
Phosphotyrosine
Focal Adhesions
2 Citations (Scopus)

Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells

Ding, Z-C., Habtetsion, T., Cao, Y., Li, T., Liu, C., Kuczma, M., Chen, T., Hao, Z., Bryan, L. J., Munn, D. H. & Zhou, G., Dec 1 2017, In : Scientific Reports. 7, 1, 12168.

Research output: Contribution to journalArticle

Interleukin-7
Cell- and Tissue-Based Therapy
T-Lymphocytes
Cytokines
Adoptive Immunotherapy
60 Citations (Scopus)

A facilitated tracking and transcription mechanism of long-range enhancer function

Zhu, X., Ling, J., Zhang, L., Pi, W., Wu, M. & Tuan Lo, D., Aug 1 2007, In : Nucleic Acids Research. 35, 16, p. 5532-5544 13 p.

Research output: Contribution to journalArticle

Globins
DNA
DNA Polymerase II
Locus Control Region
Genes
8 Citations (Scopus)

A federated network for translational cancer research using clinical data and biospecimens

Jacobson, R. S., Becich, M. J., Bollag, R. J., Chavan, G., Corrigan, J., Dhir, R., Feldman, M. D., Gaudioso, C., Legowski, E., Maihle, N. J., Mitchell, K., Murphy, M., Sakthivel, M., Tseytlin, E. & Weaver, J., Dec 15 2015, In : Cancer Research. 75, 24, p. 5194-5201 8 p.

Research output: Contribution to journalArticle

Translational Medical Research
Information Storage and Retrieval
Information Systems
Phenotype
Neoplasms
8 Citations (Scopus)

African dust and asthma in the Caribbean: Medical and statistical perspectives

Monteil, M. A. & Antoine, R., Aug 27 2009, In : International Journal of Biometeorology. 53, 5, p. 379-381 3 p.

Research output: Contribution to journalArticle

Barbados
asthma
Air Pollution
Dust
risk assessment
107 Citations (Scopus)

African dust clouds are associated with increased paediatric asthma accident and emergency admissions on the Caribbean island of Trinidad

Gyan, K., Henry, W., Lacaille, S., Laloo, A., Lamsee-Ebanks, C., McKay, S., Antoine, R. M. & Monteil, M. A., Jul 1 2005, In : International Journal of Biometeorology. 49, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

Trinidad and Tobago
West Indies
Pediatrics
asthma
Dust
53 Citations (Scopus)

A garter snake transcriptome: Pyrosequencing, de novo assembly, and sex-specific differences

Schwartz, T. S., Tae, H., Yang, Y., Mockaitis, K., Van Hemert, J. L., Proulx, S. R., Choi, J. H. & Bronikowski, A. M., Dec 7 2010, In : BMC Genomics. 11, 1, 694.

Research output: Contribution to journalArticle

Colubridae
Reptiles
Transcriptome
Sex Characteristics
Genes
64 Citations (Scopus)

A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin

Jagadeeswaran, P., Tuan Lo, D., Forget, B. G. & Weissman, S. M., Dec 1 1982, In : Nature. 296, 5856, p. 469-470 2 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Nucleic Acid Repetitive Sequences
Gene Deletion
Globins
Genes
47 Citations (Scopus)

A genome-wide methylation study of severe vitamin d deficiency in African American adolescents

Zhu, H., Wang, X., Shi, H., Su, S., Harshfield, G. A., Gutin, B., Snieder, H. & Dong, Y., Jan 1 2013, In : Journal of Pediatrics. 162, 5

Research output: Contribution to journalArticle

Avitaminosis
African Americans
Methylation
Vitamin D Deficiency
Genome