Biochemistry and Molecular Biology

Research Output 1968 2019

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1991
46 Citations (Scopus)

1,3,8-Trisubstituted Xanthines. Effects of Substitution Pattern upon Adenosine Receptor A1/A2 Affinity

Erickson, R. H., Hiner, R. N., Feeney, S. W., Blake, P. R., Rzeszotarski, W. J., Hicks, R. P., Costello, D. G. & Abreu, M. E., Apr 1 1991, In : Journal of Medicinal Chemistry. 34, 4, p. 1431-1435 5 p.

Research output: Contribution to journalArticle

Xanthines
Adenosine A2 Receptors
Adenosine A1 Receptors
varespladib methyl
44 Citations (Scopus)

A conserved sequence element in ribonuclease III processing signals is not required for accurate in vitro enzymatic cleavage

Chelladurai, B. S., Li, H. & Nicholson, A. W., Apr 25 1991, In : Nucleic Acids Research. 19, 8, p. 1759-1766 8 p.

Research output: Contribution to journalArticle

Ribonuclease III
Conserved Sequence
RNA
Base Pairing
RNA Phages
63 Citations (Scopus)

Acylation of the lymphoma transmembrane glycoprotein, GP85, may be required for GP85-ankyrin interaction

Bourguignon, L. Y. W., Kalomiris, E. L. & Lokeshwar, V. B., Nov 5 1991, In : Journal of Biological Chemistry. 266, 18, p. 11761-11765 5 p.

Research output: Contribution to journalArticle

Ankyrins
Acylation
Palmitic Acid
Lymphoma
Glycoproteins
10 Citations (Scopus)
Acquired Immunodeficiency Syndrome
HIV
Peptides
Serum
Proteins
58 Citations (Scopus)

Changes observed in antioxidant system in the blood of post-menopausal women with breast cancer

Kumar, K., Thangaraju, M. & Sachdanandam, P., Dec 1 1991, In : Biochemistry International. 25, 2, p. 371-380 10 p.

Research output: Contribution to journalArticle

Blood
Antioxidants
Breast Neoplasms
Lipid Peroxidation
Ceruloplasmin
48 Citations (Scopus)

Cloning of murine tissue factor and regulation of gene expression by transforming growth factor type β1

Ranganathan, G., Blatti, S. P., Subramaniam, M., Fass, D. N., Maihle, N. J. & Getz, M. J., Jan 31 1991, In : Journal of Biological Chemistry. 266, 1, p. 496-501 6 p.

Research output: Contribution to journalArticle

Cloning
Gene Expression Regulation
Thromboplastin
Transforming Growth Factors
Gene expression
81 Citations (Scopus)

Degradation of Oxidized Insulin B Chain by the Multiproteinase Complex Macropain (Proteasome)

Dick, L. R., Moomaw, C. R., DeMartino, G. N. & Slaughter, C. A., Mar 1 1991, In : Biochemistry. 30, 10, p. 2725-2734 10 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Insulin
Degradation
Peptides
Antipain
20 Citations (Scopus)

Growth modulation by epidermal growth factor (EGF) in human colonic carcinoma cells: Constitutive expression of the human EGF gene

Huang, S., Lin, PF. F., Fan, D., Price, J. E., Trujillo, J. M. & Chakrabarty, S., Aug 1991, In : Journal of Cellular Physiology. 148, 2, p. 220-227 8 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Genes
Cells
Modulation
Carcinoma
103 Citations (Scopus)

Molecular genetics of kinesin light chains: Generation of isoforms by alternative splicing

Cyr, J. L., Pfister, K. K., Bloom, G. S., Slaughter, C. A. & Brady, S. T., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 22, p. 10114-10118 5 p.

Research output: Contribution to journalArticle

Kinesin
Alternative Splicing
Molecular Biology
Protein Isoforms
Light
22 Citations (Scopus)

Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor

Maihle, N. J., Flickinger, T. W., Raines, M. A., Sanders, M. L. & Kung, H. J., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 5, p. 1825-1829 5 p.

Research output: Contribution to journalArticle

erbB Genes
Immune Sera
Ligands
Growth Factor Receptors
Proteins
138 Citations (Scopus)

Nonidentical subunits of p21(H-ras) farnesyltransferase. Peptide binding and farnesyl pyrophosphate carrier functions

Reiss, Y., Seabra, M. C., Armstrong, S. A., Slaughter, C. A., Goldstein, J. L. & Brown, M. S., Aug 16 1991, In : Journal of Biological Chemistry. 266, 16, p. 10672-10677 6 p.

Research output: Contribution to journalArticle

Farnesyltranstransferase
Proto-Oncogene Proteins p21(ras)
Peptides
ras Proteins
Holoenzymes
96 Citations (Scopus)
Ankyrins
Glycosylation
Biosynthesis
Post Translational Protein Processing
Lymphoma
11 Citations (Scopus)

State-dependent variation in the inhibitory effect of [D-Ala2, D-Leu5]- enkephalin on hippocampal serotonin release in ground squirrels

Kramarova, L. I., Lee, T. F., Cui, Y. & Wang, L. C. H., Jan 1 1991, In : Life sciences. 48, 2, p. 175-181 7 p.

Research output: Contribution to journalArticle

Sciuridae
Enkephalins
Serotonin
Opioid Analgesics
Hibernation
1992
65 Citations (Scopus)

An alternatively processed mRNA from the avian c-erbB gene encodes a soluble, truncated form of the receptor that can block ligand-dependent transformation

Flickinger, T. W., Maihle, N. J. & Kung, H. J., Jan 1 1992, In : Molecular and Cellular Biology. 12, 2, p. 883-893 11 p.

Research output: Contribution to journalArticle

erbB Genes
Ligands
Messenger RNA
Chickens
Transforming Growth Factor alpha
92 Citations (Scopus)

An efficient screen for peroxisome-deficient mutants of Pichia pastoris

Liu, H., Tan, X., Veenhuis, M., McCollum, D. & Cregg, J. M., Jan 1 1992, In : Journal of Bacteriology. 174, 15, p. 4943-4951 9 p.

Research output: Contribution to journalArticle

Peroxisomes
Pichia
Methanol
Oleic Acid
alcohol oxidase
1 Citation (Scopus)

Assessment of renal acidification capacity of stone formers by acid challenge test

Ahmed, A., Pendse, AK., Rajpurohit, S. K. & Singh, PP., 1992, In : Indian Journal of Clinical Biochemistry. 7, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Autophosphorylation of Skeletal Muscle Myosin Light Chain Kinase

Gao, Z. H., Stull, J. T., Moomaw, C. R., Hsu, J. & Slaughter, C. A., Feb 1 1992, In : Biochemistry. 31, 26, p. 6126-6133 8 p.

Research output: Contribution to journalArticle

Skeletal Muscle Myosins
Myosin-Light-Chain Kinase
Calmodulin
Phosphorylation
Catalytic Domain
1 Citation (Scopus)

Complete distal renal tubular acidosis: Biochemical profile of a case

Rajpurohit, S. K., Pendse, AK., Ahmed, A. & Singh, PP., 1992, In : Indian Journal of Clinical Biochemistry. 7, 2, p. 205-206 2 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Conformational analysis of met‐enkephalin in both aqueous solution and in the presence of sodium dodecyl sulfate micelles using multidimensional NMR and molecular modeling

Graham, W. H., Carter, E. S. & Hicks, R. P., Jan 1 1992, In : Biopolymers. 32, 12, p. 1755-1764 10 p.

Research output: Contribution to journalArticle

Molecular modeling
Sodium dodecyl sulfate
Micelles
Sodium Dodecyl Sulfate
Conformations
21 Citations (Scopus)

Cytomegalovirus genomes demonstrates by polymerase chain reaction in synovial fluid from rheumatoid arthritis patients

Murayama, T., Jisaki, F., Ayata, M., Sakamuro, D., Hironaka, T., Hirai, K., Tsuchiya, N., Ito, K. & Furukawa, T., Jan 1 1992, In : Clinical and Experimental Rheumatology. 10, 2, p. 161-164 4 p.

Research output: Contribution to journalArticle

Synovial Fluid
Cytomegalovirus
Rheumatoid Arthritis
Genome
Polymerase Chain Reaction
31 Citations (Scopus)

Identification and Localization of a Cysteinyl Residue Critical for the Trypsin-like Catalytic Activity of the Proteasome

Dick, L. R., Moomaw, C. R., Pramanik, B. C., DeMartino, G. N. & Slaughter, C. A., Feb 1 1992, In : Biochemistry. 31, 32, p. 7347-7355 9 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Trypsin
Catalyst activity
Peptide Hydrolases
Amino Acids
247 Citations (Scopus)

Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor

Lust, J. A., Donovan, K. A., Kline, M. P., Greipp, P. R., Kyle, R. A. & Maihle, N. J., Jan 1 1992, In : Cytokine. 4, 2, p. 96-100 5 p.

Research output: Contribution to journalArticle

Interleukin-6 Receptors
Messenger RNA
Sequence Analysis
B-Lymphocytes
Interleukin-7 Receptors
47 Citations (Scopus)

Proliferation of human colon cancer cells: Role of epidermal growth factor and transforming growth factorα

Huang, S., Trujillo, J. M. & Chakrabarty, S., Dec 2 1992, In : International Journal of Cancer. 52, 6, p. 978-986 9 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Epidermal Growth Factor
Colonic Neoplasms
Cell Line
Intercellular Signaling Peptides and Proteins
220 Citations (Scopus)

Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product

Seabra, M. C., Brown, M. S., Slaughter, C. A., Südhof, T. C. & Goldstein, J. L., Sep 18 1992, In : Cell. 70, 6, p. 1049-1057 9 p.

Research output: Contribution to journalArticle

Choroideremia
rab3A GTP-Binding Protein
Purification
Conserved Sequence
Genes
40 Citations (Scopus)

Signals from focal adhesions

Burridge, K., Petch, L. A. & Romer, L. H., Oct 1992, In : Current Biology. 2, 10, p. 537-539 3 p.

Research output: Contribution to journalArticle

Focal Adhesions
adhesion
25 Citations (Scopus)

Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles: Transport and binding

Prasad, P. D., Leibach, F. H., Mahesh, V. B. & Ganapathy, V., Nov 25 1992, In : Journal of Biological Chemistry. 267, 33, p. 23632-23639 8 p.

Research output: Contribution to journalArticle

Antiporters
Transport Vesicles
Brushes
Microvilli
Cations
64 Citations (Scopus)

The hbpA gene of Haemophilus influenzae type b encodes a heme-binding lipoprotein conserved among heme-dependent Haemophilus species

Hanson, M. S., Slaughter, C. A. & Hansen, E. J., Jan 1 1992, In : Infection and Immunity. 60, 6, p. 2257-2266 10 p.

Research output: Contribution to journalArticle

Haemophilus
Haemophilus influenzae type b
Staphylococcal Protein A
Heme
Lipoproteins
39 Citations (Scopus)

The interactions of neuropeptides with membrane model systems: A case study

Hicks, R. P., Beard, D. J. & Young, J. K., Jan 1 1992, In : Biopolymers. 32, 1, p. 85-96 12 p.

Research output: Contribution to journalArticle

Bradykinin
Substance P
Neuropeptides
Membranes
Lysophosphatidylcholines
7 Citations (Scopus)

The involvement of Ca2+ and myosin light chain kinase in collagen-induced platelet activation

Lokeshwar, V. B. & Bourguignon, L. Y. W., Jan 1 1992, In : Cell Biology International Reports. 16, 9, p. 883-897 15 p.

Research output: Contribution to journalArticle

Myosin-Light-Chain Kinase
Myosin Light Chains
Platelet Activation
Collagen
Phosphorylation
16 Citations (Scopus)

The use of UV‐visible spectroscopy for the determination of hydrophobic interactions between neuropeptides and membrane model systems

Young, J. K., Graham, W. H., Beard, D. J. & Hicks, R. P., Jan 1 1992, In : Biopolymers. 32, 8, p. 1061-1064 4 p.

Research output: Contribution to journalArticle

Lysophosphatidylcholines
Rabies
Sodium dodecyl sulfate
Micelles
Bradykinin
130 Citations (Scopus)

Transcription of the hypersensitive site HS2 enhancer in erythroid cells

Tuan, D., Kong, S. & Hu, K., Dec 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 23, p. 11219-11223 5 p.

Research output: Contribution to journalArticle

Erythroid Cells
Chloramphenicol O-Acetyltransferase
Genes
RNA
Globins
58 Citations (Scopus)

Tyrosine phosphatase activity of lymphoma CD45 (GP180) is regulated by a direct interaction with the cytoskeleton

Lokeshwar, V. B. & Bourguignon, L. Y. W., Jan 1 1992, In : Journal of Biological Chemistry. 267, 30, p. 21551-21557 7 p.

Research output: Contribution to journalArticle

Cytoskeleton
Phosphoric Monoester Hydrolases
Spectrin
Tyrosine
Lymphoma
63 Citations (Scopus)

Unification of the ferritin family of proteins

Grossman, M. J., Hinton, S. M., Minak-Bernero, V., Slaughter, C. A. & Stiefel, E. I., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 6, p. 2419-2423 5 p.

Research output: Contribution to journalArticle

Ferritins
Azotobacter vinelandii
Proteins
Environmental Monitoring
Heme
1993
28 Citations (Scopus)

Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinases

Bell, S. M., Connolly, D. C., Maihle, N. J. & Degen, J. L., Sep 1993, In : Molecular and Cellular Biology. 13, 9, p. 5888-5897 10 p.

Research output: Contribution to journalArticle

Plasminogen Activators
Oncogene Proteins
Urokinase-Type Plasminogen Activator
Protein-Tyrosine Kinases
Gene Expression
223 Citations (Scopus)

Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals

Robinson, P. J., Sontag, J. M., Liu, J. P., Fykse, E. M., Slaughter, C., McMahontt, H. & Südhof, T. C., Jan 1 1993, In : Nature. 365, 6442, p. 163-166 4 p.

Research output: Contribution to journalArticle

Dynamins
GTP Phosphohydrolases
Protein Kinase C
Phosphorylation
Endocytosis
100 Citations (Scopus)

Expression of a Cocaine-Sensitive Norepinephrine Transporter in the Human Placental Syncytiotrophoblast

Ramamoorthy, S., Prasad, P. D., Kulanthaivel, P., Leibach, F. H., Blakely, R. D. & Ganapathy, V., Jan 1 1993, In : Biochemistry. 32, 5, p. 1346-1353 8 p.

Research output: Contribution to journalArticle

Norepinephrine Plasma Membrane Transport Proteins
Trophoblasts
Cocaine
Norepinephrine
Northern Blotting
72 Citations (Scopus)

Hydroubiquinone-Cytochrome c2 Oxidoreductase from Rhodobacter capsulatus: Definition of a Minimal, Functional Isolated Preparation

Robertson, D. E., Ding, H., Chelminski, P. R., Slaughter, C. A., Hsu, J., Moomaw, C., Tokito, M., Daldal, F. & Dutton, P. L., Jan 1 1993, In : Biochemistry. 32, 5, p. 1310-1317 8 p.

Research output: Contribution to journalArticle

Cytochromes c2
Rhodobacter capsulatus
Heme
Paramagnetic resonance
Oxidoreductases
5 Citations (Scopus)

Induction of murine hepatic glutathione S-transferase by dietary dehydroepiandrosterone

Milewich, L., Marrero, M., Tezabwala, B. U., Bennett, M., Frenkel, R. A. & Slaughter, C. A., Sep 1993, In : Journal of Steroid Biochemistry and Molecular Biology. 46, 3, p. 321-329 9 p.

Research output: Contribution to journalArticle

Dehydroepiandrosterone
Glutathione Transferase
Nutrition
Liver
Diet
61 Citations (Scopus)

PA28, an activator of the 20 S proteasome, is inactivated by proteolytic modification at its carboxyl terminus

Chu-Ping, M., Willy, P. J., Slaughter, C. A. & DeMartino, G. N., Jan 1 1993, In : Journal of Biological Chemistry. 268, 30, p. 22514-22519 6 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Carboxypeptidase B
Carboxypeptidases
Proteins
Molecular Weight
62 Citations (Scopus)

Ribonuclease III cleavage of a bacteriophage T7 processing signal. Divalent cation specificity, and specific anion effects

Li, H., Chelladurai, B. S., Zhang, K. & Nicholson, A. W., Apr 25 1993, In : Nucleic Acids Research. 21, 8, p. 1919-1925 7 p.

Research output: Contribution to journalArticle

Ribonuclease III
Bacteriophage T7
Divalent Cations
Anions
Salts
41 Citations (Scopus)

Sodium- and Chloride-Dependent, Cocaine-Sensitive, High-Affinity Binding of Nisoxetine to the Human Placental Norepinephrine Transporter

Jayanthi, L. D., Prasad, P. D., Ramamoorthy, S., Mahesh, V. B., Leibach, F. H. & Ganapathy, V., Jan 1 1993, In : Biochemistry. 32, 45, p. 12178-12185 8 p.

Research output: Contribution to journalArticle

nisoxetine
Norepinephrine Plasma Membrane Transport Proteins
Cocaine
Sodium Chloride
Norepinephrine
1994
33 Citations (Scopus)

Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor

Eldredge, E. R., Korf, G. M., Christensen, T. A., Connolly, D. C., Getz, M. J. & Maihle, N. J., Nov 1994, In : Molecular and Cellular Biology. 14, 11, p. 7527-7534 8 p.

Research output: Contribution to journalArticle

fos Genes
Epidermal Growth Factor Receptor
Serum Response Element
Gene Expression
Transcription Factors
185 Citations (Scopus)

Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function

Lokeshwar, V. B., Fregien, N. & Bourguignon, L. Y. W., Aug 1 1994, In : Journal of Cell Biology. 126, 4, p. 1099-1109 11 p.

Research output: Contribution to journalArticle

Ankyrins
Hyaluronic Acid
Proteins
COS Cells
Cell Adhesion Molecules
19 Citations (Scopus)

Control of AKR fibroblast phenotype by fibronectin: Regulation of cell‐surface fibronectin binding receptor by fibronectin

Huang, S., Varani, J. & Chakrabarty, S., Jan 1 1994, In : Journal of Cellular Physiology. 161, 3, p. 470-482 13 p.

Research output: Contribution to journalArticle

Integrin alpha5beta1
Fibroblasts
Fibronectins
Phenotype
Antisense RNA
832 Citations (Scopus)

ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1

Xu, D., Emoto, N., Giaid, A., Slaughter, C., Kaw, S., deWit, D. & Yanagisawa, M., Aug 12 1994, In : Cell. 78, 3, p. 473-485 13 p.

Research output: Contribution to journalArticle

Endothelins
Metalloproteases
Endothelin-1
Chemical activation
Membranes
26 Citations (Scopus)

Elevated serum levels of transforming growth factor-α in breast cancer patients

Chakrabarty, S., Huang, S., Moskal, T. L. & Fritsche, H. A., May 16 1994, In : Cancer Letters. 79, 2, p. 157-160 4 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Breast Neoplasms
Serum
Neoplasms
Carcinoembryonic Antigen
42 Citations (Scopus)

Epidermal growth factor receptor-dependent stimulation of amphiregulin expression in androgen-stimulated human prostate cancer cells

Sehgal, I., Bailey, J., Hitzemann, K., Pittelkow, M. R. & Maihle, N. J., Jan 1 1994, In : Molecular Biology of the Cell. 5, 3, p. 339-347 9 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Androgens
Prostatic Neoplasms
Epidermal Growth Factor
Heparin
18 Citations (Scopus)

Expression of antisense fibronectin RNA in human colon carcinoma cells disrupts the regulation of carcinoembryonic antigen by transforming growth factor β1

Huang, S. & Chakrabarty, S., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 28764-28768 5 p.

Research output: Contribution to journalArticle

Antisense RNA
Carcinoembryonic Antigen
Transforming Growth Factors
Fibronectins
Colon
39 Citations (Scopus)

Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells

Prasad, P. D., Mahesh, V. B., Leibach, F. H. & Ganapathy, V., Jun 30 1994, In : BBA - Molecular Cell Research. 1222, 2, p. 309-314 6 p.

Research output: Contribution to journalArticle

Folic Acid Transporters
Probenecid
Proton Pumps
Choriocarcinoma
Folic Acid
27 Citations (Scopus)

Human placenta as a target organ for cocaine action: Interaction of cocaine with the placental serotonin transporter

Prasad, P. D., Leibach, F. H., Mahesh, V. B. & Ganapathy, V., Jan 1 1994, In : Placenta. 15, 3, p. 267-278 12 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Cocaine
Placenta
Choriocarcinoma
Microvilli