Biochemistry and Molecular Biology

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2004

Recent advances in Drosophila genomics

Davis, M. B. & White, K. P., Sep 21 2004, In : Genome Biology. 5, 8, 339.

Research output: Contribution to journalArticle

3 Scopus citations

Sasa Health exerts a protective effect on Her2/NeuN mammary tumorigenesis

Ren, M., Reilly, R. T. & Sacchi, N., Sep 1 2004, In : Anticancer research. 24, 5 A, p. 2879-2884 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Serine racemase and D-serine transport in human placenta and evidence for a transplacental gradient for D-serine in humans

Chen, Z., Huang, W., Srinivas, S. R., Jones, C. R., Ganapathy, V. & Prasad, P. D., Jul 1 2004, In : Journal of the Society for Gynecologic Investigation. 11, 5, p. 294-303 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Smoking at home is strongly associated with symptoms of asthma and rhinitis in children of primary school age in Trinidad and Tobago

Monteil, M. A., Joseph, G., Kit, C. C., Wheeler, G. & Antoine, R. M., Sep 2004, In : Revista Panamericana de Salud Publica/Pan American Journal of Public Health. 16, 3, p. 193-198 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Sperm membrane protein profiles of fertile and infertile men: Identification and characterization of fertility-associated sperm antigen

Rajeev, S. K. & Reddy, K. V. R., Feb 2004, In : Human Reproduction. 19, 2, p. 234-242 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Structure-activity relationship study of antimalarial indolo [2,1-b]quinazoline-6,12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of new antimalarial candidates

Bhattacharjee, A. K., Hartell, M. G., Nichols, D. A., Hicks, R. P., Stanton, B., Van Hamont, J. E. & Milhous, W. K., Jan 2004, In : European Journal of Medicinal Chemistry. 39, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

99 Scopus citations

The anthrax protective antigen (PA63) bound conformation of a peptide inhibitor of the binding of lethal factor to PA63: As determined by trNOESY NMR and molecular modeling

Hicks, R. P., Bhattacharjee, A. K., Koser, B. W. & Traficante, D. D., Oct 21 2004, In : Journal of Medicinal Chemistry. 47, 22, p. 5347-5355 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

The association of dimethylsulfoxide and model membranes studied by pulse-field gradient NMR

Kennedy, A., Long, C. J., Hmel, P. J., Hicks, R. & Reid, T. J., 2004, In : Spectroscopy. 18, 2, p. 265-269 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans

Pi, W., Yang, Z., Wang, J., Ruan, L., Yu, X., Ling, J., Krantz, S., Isales, C. M., Conway, S. J., Lin, S. & Tuan Lo, D., Jan 20 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 3, p. 805-810 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate

Martin, P. M., Ola, M. S., Agarwal, N., Ganapathy, V. & Smith, S. B., Apr 7 2004, In : Molecular Brain Research. 123, 1-2, p. 66-75 10 p.

Research output: Contribution to journalArticle

63 Scopus citations

Transporter-Mediated Effects of Diclofenamic Acid and Its Ascorbyl Pro-drug in the In Vivo Neurotropic Activity of Ascorbyl Nipecotic Acid Conjugate

Dalpiaz, A., Pavan, B., Scaglianti, M., Vitali, F., Bortolotti, F., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Prasad, P. & Manfredini, S., Jan 2004, In : Journal of Pharmaceutical Sciences. 93, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
2003

Activation of cGMP-dependent protein kinase by protein kinase C

Hou, Y., Lascola, J., Dulin, N. O., Ye, R. D. & Browning, D. D., May 9 2003, In : Journal of Biological Chemistry. 278, 19, p. 16706-16712 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Climatic variables are associated with seasonal acute asthma admissions to accident and emergency room facilities in Trinidad, West Indies

Ivey, M. A., Simeon, D. T. & Monteil, M. A., Nov 1 2003, In : Clinical and Experimental Allergy. 33, 11, p. 1526-1530 5 p.

Research output: Contribution to journalArticle

37 Scopus citations

Comparison of the conformation and electrostatic surface properties of magainin peptides bound to sodium dodecyl sulfate and dodecylphosphocholine micelles

Hicks, R. P., Mones, E., Kim, H., Koser, B. W., Nichols, D. A. & Bhattacharjee, A. K., Apr 1 2003, In : Biopolymers. 68, 4, p. 459-470 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer

Yan, P. S., Shi, H., Rahmatpanah, F., Hsiau, T. H. C., Hsiau, A. H. A., Leu, Y. W., Liu, J. C. & Huang, T. H. M., Oct 1 2003, In : Cancer Research. 63, 19, p. 6178-6186 9 p.

Research output: Contribution to journalArticle

103 Scopus citations

Differential regulation of cell motility and invasion by FAK

Hsia, D. A., Mitra, S. K., Hauck, C. R., Streblow, D. N., Nelson, J. A., Ilic, D., Huang, S., Li, E., Nemerow, G. R., Leng, J., Spencer, K. S. R., Cheresh, D. A. & Schlaepfer, D. D., Mar 3 2003, In : Journal of Cell Biology. 160, 5, p. 753-767 15 p.

Research output: Contribution to journalArticle

423 Scopus citations

Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation

Leu, Y. W., Rahmatpanah, F., Shi, H., Wei, S. H., Liu, J. C., Yan, P. S. & Huang, T. H. M., Oct 1 2003, In : Cancer Research. 63, 19, p. 6110-6115 6 p.

Research output: Contribution to journalArticle

127 Scopus citations
15 Scopus citations

Functional significance of protein kinase A activation by endothelin-1 and ATP: Negative regulation of SRF-dependent gene expression by PKA

Davis, A., Hogarth, K., Fernandes, D., Solway, J., Niu, J., Kolenko, V., Browning, D., Miano, J. M., Orlov, S. N. & Dulin, N. O., Jun 1 2003, In : Cellular Signalling. 15, 6, p. 597-604 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Genetically obese MMTV-TGF-α/Lepob Lepob female mice do not develop mammary tumors

Cleary, M. P., Phillips, F. C., Getzin, S. C., Jacobson, T. L., Jacobson, M. K., Christensen, T. A., Juneja, S. C., Grande, J. P. & Maihle, N. J., Feb 1 2003, In : Breast Cancer Research and Treatment. 77, 3, p. 205-215 11 p.

Research output: Contribution to journalArticle

130 Scopus citations

Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.

Boerner, J. L., Danielsen, A. J., Lovejoy, C. A., Wang, Z., Juneja, S. C., Faupel-Badger, J. M., Darce, J. R. & Maihle, N. J., Oct 2 2003, In : Oncogene. 22, 43, p. 6679-6689 11 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
42 Scopus citations

Identification of Uhp1, a ubiquitinated histone-like protein, as a target/mediator of Rhp6 in mating-type silencing in fission yeast

Naresh, A., Saini, S. & Singh, J., Mar 14 2003, In : Journal of Biological Chemistry. 278, 11, p. 9185-9194 10 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Involvement of protein tyrosine kinase in toll-like receptor 4-mediated NF-κB activation in human peripheral blood monocytes

Chen, L. Y., Zuraw, B. L., Zhao, M., Liu, F. T., Huang, S. & Pan, Z. K., Apr 1 2003, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 284, 4 28-4, p. L607-L613

Research output: Contribution to journalArticle

53 Scopus citations

Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood-brain barrier

Friedrich, A., Prasad, P. D., Freyer, D., Ganapathy, V. & Brust, P., Apr 4 2003, In : Brain Research. 968, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Soluble epidermal growth factor receptor (sEGFR/sErbB1) as a potential risk, screening, and diagnostic serum biomarker of epithelial ovarian cancer

Baron, A. T., Cora, E. M., Lafky, J. M., Boardman, C. H., Buenafe, M. C., Rademaker, A., Liu, D., Fishman, D. A., Podratz, K. C. & Maihle, N. J., Feb 1 2003, In : Cancer Epidemiology Biomarkers and Prevention. 12, 2, p. 103-113 11 p.

Research output: Contribution to journalArticle

83 Scopus citations

TAB1β (transforming growth factor-β-activated protein kinase 1-binding protein 1β), a novel splicing variant of TAB1 that interacts with p38α but not TAK1

Ge, B., Xiong, X., Jing, Q., Mosley, J. L., Filose, A., Bian, D., Huang, S. & Han, J., Jan 24 2003, In : Journal of Biological Chemistry. 278, 4, p. 2286-2293 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

The ERV-9 LTR enhancer is not blocked by the HS5 insulator and synthesizes through the HS5 site non-coding, long RNAs that regulate LTR enhancer function

Ling, J., Pi, W., Yu, X., Bengra, C., Long, Q., Jin, H., Seyfang, A. & Tuan, D., Aug 1 2003, In : Nucleic Acids Research. 31, 15, p. 4582-4596 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

Transgenic mice demonstrate novel promoter regions for tissue-specific expression of the urokinase receptor gene

Wang, H., Hicks, J., Khanbolooki, P., Kim, S. J., Yan, C., Wang, Y. & Boyd, D., Aug 1 2003, In : American Journal of Pathology. 163, 2, p. 453-464 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Triple analysis of the cancer epigenome: An integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation

Shi, H., Wei, S. H., Leu, Y. W., Rahmatpanah, F., Liu, J. C., Yan, P. S., Nephew, K. P. & Huang, T. H. M., May 1 2003, In : Cancer Research. 63, 9, p. 2164-2171 8 p.

Research output: Contribution to journalArticle

125 Scopus citations

α6β1 integrin is a potential clinical marker for evaluating sperm quality in men

Reddy, V. R. K., Rajeev, S. K. & Gupta, V., Jun 1 2003, In : Fertility and sterility. 79, SUPPL. 3, p. 1590-1596 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
2002

A chromosomal region 7p11.2 transcript map: Its development and application to the study of EGFR amplicons in glioblastoma

Eley, G. D., Reiter, J. L., Pandita, A., Park, S., Jenkins, R. B., Maihle, N. J. & James, C. D., Jan 1 2002, In : Neuro-Oncology. 4, 2, p. 86-94 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
74 Scopus citations

Amphiphilic gels with controlled mesh dimensions for insulin delivery

Kennedy, J. P., Fenyvesi, G., Na, S., Keszler, B. & Rosenthal, K. S., Dec 1 2002, In : ACS Symposium Series. 833, 1, p. 710-711 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Analysis of genome by visualization of genomic signature

Choi, J-H., Lee, S. K., Yee, S. B., Kim, Y. J., Cho, H. G. & Kim, K. W., Mar 1 2002, In : Korean Journal of Genetics. 24, 1, p. 97-104 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Analysis of sigma receptor (σR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice

Shamsul Ola, M., Martin, P. M., Maddox, D., El-Sherbeny, A., Huang, W., Roon, P., Agarwal, N., Ganapathy, V. & Smith, S. B., Nov 15 2002, In : Molecular Brain Research. 107, 2, p. 97-107 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

A randomized phase II study of sequential docetaxel and doxorubicin/cyclophosphamide in patients with metastatic breast cancer

Kugler, J. W., Perez, E. A., Geeraerts, L., Lafky, J. M., Ingle, J. N., Suman, V. J., Adjei, A. A., Baron, A. T., Hatfield, A. K., Maihle, N., Michalak, J. C. & Kuross, S. A., Aug 1 2002, In : Annals of Oncology. 13, 8, p. 1225-1235 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Capillary electrophoresis determination of biflavanones from Garcinia kola in three traditional African medicinal formulations

Okunji, C. O., Ware, T. A., Hicks, R. P., Iwu, M. M. & Skanchy, D. J., Jun 19 2002, In : Planta Medica. 68, 5, p. 440-444 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Characterization of the main phase transition in 1,2-dipalmitoyl-phosphatidylcholine LUVs by 1H NMR

Kennedy, A., Hmel, P. J., Seelbaugh, J., Quiles, J. G., Hicks, R. & Reid, T. J., Dec 12 2002, In : Journal of Liposome Research. 12, 3, p. 221-237 17 p.

Research output: Contribution to journalArticle

13 Scopus citations

Comparing mRNA levels of genes encoding leptin, leptin receptor, and lipoprotein lipase between dairy and beef cattle

Ren, M. Q., Wegner, J., Bellmann, O., Brockmann, G. A., Schneider, F., Teuscher, F. & Ender, K., Oct 1 2002, In : Domestic Animal Endocrinology. 23, 3, p. 371-381 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity

Manfredini, S., Pavan, B., Vertuani, S., Scaglianti, M., Compagnone, D., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Prasad, P. D. & Dalpiaz, A., Jan 31 2002, In : Journal of Medicinal Chemistry. 45, 3, p. 559-562 4 p.

Research output: Contribution to journalArticle

85 Scopus citations

Dissociated ROS production and ceramide generation in sulfasalazine-induced cell death in Raw 264.7 cells

Salh, B., Assi, K., Huang, S., O'Brien, L., Steinbrecher, U. & Gómez-Muñoz, A., Oct 1 2002, In : Journal of Leukocyte Biology. 72, 4, p. 790-799 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells

Bachmann, A., Hanke, B., Zawatzky, R., Soto, U., Van Riggelen, J., Zur Hausen, H. & Rösl, F., Jan 1 2002, In : Journal of Virology. 76, 1, p. 280-291 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice

Naggar, H., Shamsul Ola, M., Martin, P. M., Huang, W., Bridges, C. C., Ganapathy, V. & Smith, S. B., Feb 11 2002, In : Investigative Ophthalmology and Visual Science. 43, 2, p. 556-563 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Effect of moderate caloric restriction and/or weight cycling on mammary tumor incidence and latency in MMTV-Neu female mice

Pape-Ansorge, K. A., Grande, J. P., Christensen, T. A., Maihle, N. J. & Cleary, M. P., Jan 1 2002, In : Nutrition and Cancer. 44, 2, p. 162-168 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

EGF receptor/ErbB isoforms as serum biomarkers in breast and ovarian cancer

Maihle, N. J., Lafky, J. M., Baron, A. T., Boardman, C. H., Greenwood, T. M., Christensen, T. A., Reiter, J. L., Cora, E. M., Lee, H., Suman, V. J., Fishman, D. A., Perez, E. A. & Podratz, K. C., Mar 1 2002, In : Journal of Clinical Ligand Assay. 25, 1, p. 57-60 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Endogenous reactivation of the RARβ2 tumor suppressor gene epigenetically silenced in breast cancer

Sirchia, S. M., Ren, M., Pili, R., Sironi, E., Somenzi, G., Ghidoni, R., Toma, S., Nicolò, G. & Sacchi, N., May 1 2002, In : Cancer Research. 62, 9, p. 2455-2461 7 p.

Research output: Contribution to journalArticle

145 Scopus citations

Generation and characterization of polyclonal antibodies specific for human p110 sEGFR

Christensen, T. A., Reiter, J. L., Baron, A. T. & Maihle, N. J., Jan 1 2002, In : Hybridoma and Hybridomics. 21, 3, p. 183-189 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

Wiemann, S. U., Ande, S., Tsahuridu, M., Tillmann, H. L., Zender, L., Klempnauer, J., Flemming, P., Franco, S., Blasco, M. A., Manns, M. P. & Lenhard Rudolph, K., Jul 22 2002, In : FASEB Journal. 16, 9, p. 935-942 8 p.

Research output: Contribution to journalArticle

338 Scopus citations