Biochemistry and Molecular Biology

Research Output 1968 2019

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2018
3 Citations (Scopus)

Sustained persistence of il2 signaling enhances the antitumor effect of peptide vaccines through t-cell expansion and preventing pd-1 inhibition

Sultan, H., Kumai, T., Fesenkova, V. I., Fan, A. E., Wu, J., Cho, H. II., Kobayashi, H., Harabuchi, Y. & Celis, E., May 2018, In : Cancer Immunology Research. 6, 5, p. 617-627 11 p.

Research output: Contribution to journalArticle

Subunit Vaccines
Interleukin-2
T-Lymphocytes
Neoplasms
Neoplasm Antigens
6 Citations (Scopus)

Suxiao Jiuxin pill promotes exosome secretion from mouse cardiac mesenchymal stem cells in vitro

Ruan, X. F., Ju, C. W., Shen, Y., Liu, Y., Kim, I., Yu, H., Weintraub, N. L., Wang, X. L. & Tang, Y. L., Apr 1 2018, In : Acta Pharmacologica Sinica. 39, 4, p. 569-578 10 p.

Research output: Contribution to journalArticle

Exosomes
Mesenchymal Stromal Cells
Sphingomyelin Phosphodiesterase
GTP Phosphohydrolases
Therapeutics
2 Citations (Scopus)

Synergistic Targeting HER2 and EGFR with Bivalent Aptamer-siRNA Chimera Efficiently Inhibits HER2-Positive Tumor Growth

Xue, L., Maihle, N. J., Yu, X., Tang, S. C. & Liu, H., Nov 5 2018, In : Molecular Pharmaceutics. 15, 11, p. 4801-4813 13 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Breast Neoplasms
Growth
Drug Resistance
Pharmaceutical Preparations
12 Citations (Scopus)

Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer

Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In : Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Breast Neoplasms
Nucleotide Aptamers
Antibodies
Heterografts
2 Citations (Scopus)

Targeting the MYC oncogene in burkitt lymphoma through HSP90 inhibition

Poole, C. J., Zheng, W., Lee, H., Young, D., Lodh, A., Chadli, A. & Van Riggelen, J., Nov 16 2018, In : Cancers. 10, 11, 448.

Research output: Contribution to journalArticle

Burkitt Lymphoma
Oncogenes
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
tanespimycin
Proteins
1 Citation (Scopus)

Tauroursodeoxycholic acid alleviates secondary injury in the spinal cord via up-regulation of CIBZ gene

Zhang, Z., Chen, J., Chen, F., Yu, D., Li, R., Lv, C., Wang, H., Li, H., Li, J. & Cai, Y., Jul 1 2018, In : Cell Stress and Chaperones. 23, 4, p. 551-560 10 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Up-Regulation
Genes
Endoplasmic Reticulum Stress
Apoptosis
3 Citations (Scopus)
STAT1 Transcription Factor
effectors
ischemia
kidneys
Reperfusion Injury
5 Citations (Scopus)

The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer

Kadi, N. E., Wang, L., Davis, A., Korkaya, H., Cooke, A., Vadnala, V., Brown, N. A., Betz, B. L., Cascalho, M., Kalemkerian, G. P. & Hassan, K. A., Dec 15 2018, In : Cancer Research. 78, 24, p. 6728-6735 8 p.

Research output: Contribution to journalArticle

5-Methylcytosine
Deamination
Protein-Tyrosine Kinases
Lung Neoplasms
Mutation
9 Citations (Scopus)

The innate immune receptor TREM-1 promotes liver injury and fibrosis

Nguyen, A. T., Ajith, A., Portik-Dobos, V., Horuzsko, D. D., Arbab, A. S., Dzutsev, A., Sadek, R. F., Trinchieri, G. & Horuzsko, A., Nov 1 2018, In : Journal of Clinical Investigation. 128, 11, p. 4870-4883 14 p.

Research output: Contribution to journalArticle

Myeloid Cells
Liver Cirrhosis
Liver
Wounds and Injuries
Kupffer Cells
6 Citations (Scopus)

The MIR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase

Hu, T., Chong, Y., Qin, H., Kitamura, E., Chang, C. S., Silva, J., Ren, M. & Cowell, J. K., Apr 1 2018, In : Oncogene. 37, 14, p. 1926-1938 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Phosphotransferases
Cell Proliferation
B-Cell Leukemia
Porifera
8 Citations (Scopus)

The tumor secretory factor ZAG promotes white adipose tissue browning and energy wasting

Elattar, S., Dimri, M. & Ande, S., Sep 1 2018, In : FASEB Journal. 32, 9, p. 4727-4743 17 p.

Research output: Contribution to journalArticle

White Adipose Tissue
Zinc
Tumors
Glycoproteins
Tissue
1 Citation (Scopus)

Thymoquinone prevents cisplatin neurotoxicity in primary DRG neurons

Üstün, R., Oğuz, E. K., Şeker, A. & Korkaya, H., Dec 1 2018, In : NeuroToxicology. 69, p. 68-76 9 p.

Research output: Contribution to journalArticle

Spinal Ganglia
Cisplatin
Neurons
Chemotherapy
Peripheral Nervous System Diseases
3 Citations (Scopus)

Thymoquinone protects DRG neurons from axotomy-induced cell death

Üstün, R., Oğuz, E. K., Şeker, A. & Korkaya, H., Nov 2 2018, In : Neurological Research. 40, 11, p. 930-937 8 p.

Research output: Contribution to journalArticle

Axotomy
Spinal Ganglia
Cell Death
Neurons
Peripheral Nerve Injuries
6 Citations (Scopus)

Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200c

Abisoye-Ogunniyan, A., Lin, H., Ghebremedhin, A., Salam, A. B., Karanam, B., Theodore, S., Jones-Trich, J., Davis, M. B., Grizzle, W., Wang, H. & Yates, C., Sep 1 2018, In : Cancer Letters. 431, p. 1-10 10 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Prostatic Neoplasms
Neoplasm Metastasis
Epidermal Growth Factor
DNA Methylation
7 Citations (Scopus)

Transgelin-2 as a therapeutic target for asthmatic pulmonary resistance

Yin, L. M., Xu, Y. D., Peng, L. L., Duan, T. T., Liu, J. Y., Xu, Z., Wang, W. Q., Guan, N., Han, X. J., Li, H. Y., Pang, Y., Wang, Y., Chen, Z., Zhu, W., Deng, L., Wu, Y. L., Ge, G. B., Huang, S., Ulloa, L. & Yang, Y. Q., Feb 7 2018, In : Science Translational Medicine. 10, 427, eaam8604.

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Lung
Metallothionein
Asthma
Myosin-Light-Chain Phosphatase
6 Citations (Scopus)

Transplantation of Cardiac Mesenchymal Stem Cell-Derived Exosomes Promotes Repair in Ischemic Myocardium

Ju, C., Shen, Y., Ma, G., Liu, Y., Cai, J., Kim, I., Weintraub, N. L., Liu, N. & Tang, Y. L., Jan 1 2018, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalArticle

Mesenchymal Stem Cell Transplantation
Exosomes
Myocardium
Myocardial Infarction
Cardiac Myocytes
7 Citations (Scopus)

Ufm1-Specific Ligase Ufl1 Regulates Endoplasmic Reticulum Homeostasis and Protects Against Heart Failure

Li, J., Yue, G., Ma, W., Zhang, A., Zou, J., Cai, Y., Tang, X., Wang, J., Liu, J., Li, H. & Su, H., Oct 1 2018, In : Circulation. Heart failure. 11, 10, p. e004917

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Ligases
Ubiquitin
Endoplasmic Reticulum
Homeostasis

ZBTB38, a novel regulator of autophagy initiation targeted by RB1CC1/FIP200 in spinal cord injury

Chen, J., Yan, L., Wang, H., Zhang, Z., Yu, D., Xing, C., Li, J., Li, H., Li, J. & Cai, Y., Dec 15 2018, In : Gene. 678, p. 8-16 9 p.

Research output: Contribution to journalArticle

Autophagy
Spinal Cord Injuries
Transcriptome
Spinal Cord
Lentivirus
3 Citations (Scopus)

α-Lipoic acid inhibits the migration and invasion of breast cancer cells through inhibition of TGFβ signaling

Tripathy, J., Tripathy, A., Thangaraju, M., Suar, M. & Elangovan, S., Aug 15 2018, In : Life sciences. 207, p. 15-22 8 p.

Research output: Contribution to journalArticle

Thioctic Acid
Cells
Breast Neoplasms
Neoplasm Metastasis
Cell Migration Inhibition
3 Citations (Scopus)

β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling

Teoh, J. P., Bayoumi, A. S., Aonuma, T., Xu, Y., Johnson, J. A., Su, H., Weintraub, N. L., Tang, Y. L. & Kim, I., May 1 2018, In : Journal of molecular and cellular cardiology. 118, p. 225-236 12 p.

Research output: Contribution to journalArticle

Arrestin
MicroRNAs
Adrenergic Receptors
Arrestins
Ribonuclease III
2017
2 Citations (Scopus)

Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells

Ding, Z-C., Habtetsion, T., Cao, Y., Li, T., Liu, C., Kuczma, M., Chen, T., Hao, Z., Bryan, L. J., Munn, D. H. & Zhou, G., Dec 1 2017, In : Scientific Reports. 7, 1, 12168.

Research output: Contribution to journalArticle

Interleukin-7
Cell- and Tissue-Based Therapy
T-Lymphocytes
Cytokines
Adoptive Immunotherapy
4 Citations (Scopus)

Agonist anti-GITR antibody significantly enhances the therapeutic efficacy of Listeria monocytogenes-based immunotherapy

Shrimali, R. K., Ahmad, S., Berrong, Z., Okoev, G., Matevosyan, A., Razavi, G. S. E., Petit, R., Gupta, S., Mkrtichyan, M. & Khleif, S. N., Aug 15 2017, In : Journal for ImmunoTherapy of Cancer. 5, 1, 64.

Research output: Contribution to journalArticle

Listeria monocytogenes
Immunotherapy
Anti-Idiotypic Antibodies
Neoplasms
Listeria
7 Citations (Scopus)

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

Mangaonkar, A., Mondal, A. K., Fulzule, S., Pundkar, C., Park, E. J., Jillella, A., Kota, V., Xu, H., Savage, N. M., Shi, H., Munn, D. H. & Kolhe, R. B., Dec 1 2017, In : Scientific Reports. 7, 1, 12892.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Acute Myeloid Leukemia
Mortality
Messenger RNA
Bone Marrow
1 Citation (Scopus)

Anti-HER-2 therapy following severe trastuzumab-induced cardiac toxicity

Sadek, I., Keaton, M., Maihle, N. J. & Tang, S-C., Sep 1 2017, In : Genes and Diseases. 4, 3, p. 159-162 4 p.

Research output: Contribution to journalArticle

Toxicity
Thoracic Wall
Breast Neoplasms
Therapeutics
Disease control
16 Citations (Scopus)

Anti-Jagged immunotherapy inhibits MDSCs and overcomes tumor-induced tolerance

Sierra, R. A., Trillo-Tinoco, J., Mohamed, E., Yu, L., Achyut, B. R., Arbab, A. S., Bradford, J. W., Osborne, B. A., Miele, L. & Rodriguez, P. C., Oct 15 2017, In : Cancer Research. 77, 20, p. 5628-5638 11 p.

Research output: Contribution to journalArticle

Immunotherapy
Neoplasms
T-Lymphocytes
Myeloid-Derived Suppressor Cells
Growth
6 Citations (Scopus)

Antitumor activity of sulfated hyaluronic acid fragments in pre-clinical models of bladder cancer

Jordan, A. R., Lokeshwar, S. D., Lopez, L. E., Hennig, M., Chipollini, J., Yates, T., Hupe, M. C., Merseburger, A. S., Shiedlin, A., Cerwinka, W. H., Liu, K. & Lokeshwar, V. B., Jan 1 2017, In : Oncotarget. 8, 15, p. 24262-24274 13 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Urinary Bladder Neoplasms
Catenins
1-Phosphatidylinositol 4-Kinase
Neoplasms
10 Citations (Scopus)

Augmentation of the anticancer activity of CYT997 in human prostate cancer by inhibiting Src activity

Teng, Y., Cai, Y., Pi, W., Gao, L. & Shay, C., Jun 12 2017, In : Journal of Hematology and Oncology. 10, 1, 118.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Pharmaceutical Preparations
Microtubules
Neoplasms
Cell Survival
39 Citations (Scopus)

Biased g protein-coupled receptor signaling: New player in modulating physiology and pathology

Bologna, Z., Teoh, J. P., Bayoumi, A. S., Tang, Y. L. & Kim, I., Jan 1 2017, In : Biomolecules and Therapeutics. 25, 1, p. 12-25 14 p.

Research output: Contribution to journalArticle

Physiology
Pathology
G-Protein-Coupled Receptors
Arrestins
GTP-Binding Proteins

CAME: Identification of chromatin accessibility from nucleosome occupancy and methylome sequencing

Piao, Y., Lee, S. K., Lee, E. J., Robertson, K. D., Shi, H., Ryu, K. H. & Choi, J-H., Apr 15 2017, In : Bioinformatics. 33, 8, p. 1139-1146 8 p.

Research output: Contribution to journalArticle

Methylation
Nucleosomes
Chromatin
Accessibility
Sequencing
4 Citations (Scopus)

Canonical NFκB signaling in myeloid cells is required for the glioblastoma growth

Achyut, B. R., Angara, K., Jain, M., Borin, T. F., Rashid, M. H., Iskander, A. S. M., Ara, R., Kolhe, R. B., Howard, S., Venugopal, N., Rodriguez, P. C., Bradford, J. W. & Arbab, A. S., Dec 1 2017, In : Scientific Reports. 7, 1, 13754.

Research output: Contribution to journalArticle

Myeloid Cells
Glioblastoma
NF-kappa B
Growth
Neoplasms
13 Citations (Scopus)

Cardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy

Li, J., Ma, W., Yue, G., Tang, Y. L., Kim, I., Weintraub, N. L., Wang, X. & Su, H., Jan 1 2017, In : Journal of molecular and cellular cardiology. 102, p. 53-60 8 p.

Research output: Contribution to journalArticle

Diabetic Cardiomyopathies
Proteasome Endopeptidase Complex
Ubiquitin
Experimental Diabetes Mellitus
Proteins
5 Citations (Scopus)

cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium

Wang, R., Islam, B. N., Bridges, A., Sharman, S. K., Hu, M., Hou, Y., Somanath, P. R., Venable, L., Singh, N., Kim, S., Sridhar, S., Hofmann, F. & Browning, D. D., Feb 1 2017, In : American Journal of Pathology. 187, 2, p. 377-389 13 p.

Research output: Contribution to journalArticle

Colon
Epithelium
Antioxidants
Gene Expression
Colonic Neoplasms
41 Citations (Scopus)

Concurrent PD-1 blockade negates the effects of OX40 agonist antibody in combination immunotherapy through inducing T-cell apoptosis

Shrimali, R. K., Ahmad, S., Verma, V., Zeng, P., Ananth, S., Gaur, P., Gittelman, R. M., Yusko, E., Sanders, C., Robins, H., Hammond, S. A., Janik, J. E., Mkrtichyan, M., Gupta, S. & Khleif, S. N., Sep 2017, In : Cancer Immunology Research. 5, 9, p. 755-766 12 p.

Research output: Contribution to journalArticle

Immunotherapy
Apoptosis
T-Lymphocytes
Antibodies
Vaccines
1 Citation (Scopus)

Design, synthesis and biological activities of quinazoline containing sorafenib analogs as antitumor agents

Zhang, J., Wang, N., Xie, X., Yan, C., Fu, F., Yao, J. & Wang, H., Jun 1 2017, In : Wuhan University Journal of Natural Sciences. 22, 3, p. 239-246 8 p.

Research output: Contribution to journalArticle

Quinazolines
Cytotoxicity
Bioactivity
Antineoplastic Agents
Cells
22 Citations (Scopus)

Differential PI3Kδ signaling in CD4+ T-cell subsets enables selective targeting of t regulatory cells to enhance cancer immunotherapy

Ahmad, S., Abu-Eid, R., Shrimali, R. K., Webb, M., Verma, V., Doroodchi, A., Berrong, Z., Samara, R., Rodriguez, P. C., Mkrtichyan, M. & Khleif, S. N., Apr 15 2017, In : Cancer Research. 77, 8, p. 1892-1904 13 p.

Research output: Contribution to journalArticle

T-Lymphocyte Subsets
Phosphatidylinositol 3-Kinases
Immunotherapy
Neoplasms
T-Lymphocytes
8 Citations (Scopus)

DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes, including interferon regulatory factor 8

Guo, C., Pei, L., Xiao, X., Wei, Q., Chen, J., Ding, H., Huang, S., Fan, G., Shi, H. & Dong, Z., Nov 1 2017, In : Kidney International. 92, 5, p. 1194-1205 12 p.

Research output: Contribution to journalArticle

DNA Methylation
Cisplatin
Acute Kidney Injury
Kidney
Wounds and Injuries
7 Citations (Scopus)

DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma

Poole, C. J., Zheng, W., Lodh, A., Yevtodiyenko, A., Liefwalker, D., Li, H., Felsher, D. W. & Van Riggelen, J., Jan 1 2017, In : Oncotarget. 8, 44, p. 76898-76920 23 p.

Research output: Contribution to journalArticle

Burkitt Lymphoma
DNA Methylation
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Maintenance
T-Lymphocytes
8 Citations (Scopus)

Efficacy of melatonin, IL-25 and siIL-17B in tumorigenesis-associated properties of breast cancer cell lines

Gelaleti, G. B., Borin, T. F., Maschio-Signorini, L. B., Moschetta, M. G., Jardim-Perassi, B. V., Calvinho, G. B., Facchini, M. C., Viloria-Petit, A. M. & de Campos Zuccari, D. A. P., Aug 15 2017, In : Life sciences. 183, p. 98-109 12 p.

Research output: Contribution to journalArticle

Interleukin-17
Melatonin
Carcinogenesis
Cells
Breast Neoplasms
16 Citations (Scopus)
Nanofibers
Polycaprolactone
Paclitaxel
Encapsulation
Fluorouracil
15 Citations (Scopus)

Enhanced therapeutic efficacy and memory of tumor-specific CD8 T cells by ex vivo PI3K-δ inhibition

Abu Eid, R., Ahmad, S., Lin, Y., Webb, M., Berrong, Z., Shrimali, R. K., Kumai, T., Ananth, S., Rodriguez, P. C., Celis, E., Janik, J. E., Mkrtichyan, M. & Khleif, S. N., Aug 1 2017, In : Cancer Research. 77, 15, p. 4135-4145 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
T-Lymphocytes
Aptitude
Neoplasms
Protein Isoforms
27 Citations (Scopus)

Epithelial-mesenchymal transition of ovarian cancer cells is sustained by Rac1 through simultaneous activation of MEK1/2 and Src signaling pathways

Fang, D., Chen, H., Zhu, J. Y., Wang, W., Teng, Y., Ding, H., Jing, Q., Su, S. B. & Huang, S., Mar 1 2017, In : Oncogene. 36, 11, p. 1546-1558 13 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Mitogens
Ovarian Neoplasms
33 Citations (Scopus)

FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib

Gao, L., Wang, X., Tang, Y. L., Huang, S., Hu, C. A. A. & Teng, Y., Jan 9 2017, In : Journal of Experimental and Clinical Cancer Research. 36, 1, 8.

Research output: Contribution to journalArticle

Fibroblast Growth Factors
Hepatocellular Carcinoma
Apoptosis
sorafenib
Clustered Regularly Interspaced Short Palindromic Repeats
5 Citations (Scopus)
Lymphoid Tissue
Cyclooxygenase 2
Dinoprostone
Homeostasis
T-Lymphocytes
4 Citations (Scopus)

HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model

Borin, T. F., Shankar, A., Angara, K., Rashid, M. H., Jain, M., Iskander, A., Ara, R., Lebedyeva, I. O., Korkaya, H., Achyut, B. R. & Arbab, A. S., Jun 1 2017, In : PloS one. 12, 6, 0178830.

Research output: Contribution to journalArticle

metastasis
breast neoplasms
Tumors
animal models
lungs
12 Citations (Scopus)

High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver

Zhou, D., Hlady, R. A., Schafer, M. J., White, T. A., Liu, C., Choi, J-H., Miller, J. D., Roberts, L. R., LeBrasseur, N. K. & Robertson, K. D., Jan 2 2017, In : Epigenetics. 12, 1, p. 55-69 15 p.

Research output: Contribution to journalArticle

High Fat Diet
Diet
Liver
DNA
DNA Methylation
12 Citations (Scopus)

Hyaluronic acid family in bladder cancer: Potential prognostic biomarkers and therapeutic targets

Morera, D. S., Hennig, M. S., Talukder, A., Lokeshwar, S. D., Wang, J., Garcia-Roig, M., Ortiz, N., Yates, T. J., Lopez, L. E., Kallifatidis, G., Kramer, M. W., Jordan, A. R., Merseburger, A. S., Manoharan, M., Soloway, M. S., Terris, M. K. & Lokeshwar, V. B., Nov 7 2017, In : British Journal of Cancer. 117, 10, p. 1507-1517 11 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Urinary Bladder Neoplasms
Hymecromone
Biomarkers
Atlases
1 Citation (Scopus)

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with index of hydroxyurea responsiveness

Zhu, X., Hu, T., Ho, M. H., Wang, Y., Yu, M., Patel, N., Pi, W., Choi, J-H., Xu, H., Ganapathy, V., Kutlar, F., Kutlar, A. & Tuan Lo, D., Nov 30 2017, In : Haematologica. 102, 12, p. 1995-2004 10 p.

Research output: Contribution to journalArticle

Erythroblasts
Hydroxyurea
Globins
Sickle Cell Anemia
Genes
5 Citations (Scopus)

Hypermethylated LTR retrotransposon exhibits enhancer activity

Hu, T., Zhu, X., Pi, W., Yu, M., Shi, H. & Tuan Lo, D., Mar 4 2017, In : Epigenetics. 12, 3, p. 226-237 12 p.

Research output: Contribution to journalArticle

Retroelements
Endogenous Retroviruses
Globins
Genes
DNA
9 Citations (Scopus)

Id1 promotes obesity by suppressing brown adipose thermogenesis and white adipose browning

Patil, M., Sharma, B. K., Elattar, S., Chang, J., Kapil, S., Yuan, J. & Satyanarayana, A., Jun 1 2017, In : Diabetes. 66, 6, p. 1611-1625 15 p.

Research output: Contribution to journalArticle

Brown Adipose Tissue
Thermogenesis
Obesity
White Adipose Tissue
Energy Metabolism
5 Citations (Scopus)

Inhibition of Epithelial-Mesenchymal Transition and Metastasis by Combined TGFbeta Knockdown and Metformin Treatment in a Canine Mammary Cancer Xenograft Model

Leonel, C., Borin, T. F., de Carvalho Ferreira, L., Moschetta, M. G., Bajgelman, M. C., Viloria-Petit, A. M. & de Campos Zuccari, D. A. P., Mar 1 2017, In : Journal of Mammary Gland Biology and Neoplasia. 22, 1, p. 27-41 15 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Metformin
Heterografts
Transforming Growth Factor beta
Canidae