Biochemistry and Molecular Biology

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2001

Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4)

Friedrich, A., George, R. L., Bridges, C. C., Prasad, P. D. & Ganapathy, V., Jun 6 2001, In : Biochimica et Biophysica Acta - Biomembranes. 1512, 2, p. 299-307 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Vitamin C transport in human lens epithelial cells: Evidence for the presence of SVCT2

Kannan, R., Stolz, A., Ji, Q., Prasad, P. D. & Ganapathy, V., Jan 1 2001, In : Experimental eye research. 73, 2, p. 159-165 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

α/βTCRs differ in the degree of their specificity for the positively selecting MHC/peptide ligand

Kraj, P., Pacholczyk, R. & Ignatowicz, L., Feb 15 2001, In : Journal of Immunology. 166, 4, p. 2251-2259 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

αv Integrin, p38 Mitogen-activated Protein Kinase, and Urokinase Plasminogen Activator Are Functionally Linked in Invasive Breast Cancer Cells

Chen, J., Baskerville, C., Han, Q., Pan, Z. K. & Huang, S., Dec 21 2001, In : Journal of Biological Chemistry. 276, 51, p. 47901-47905 5 p.

Research output: Contribution to journalArticle

51 Scopus citations
2000

A (GATA)7 motif located in the 5' boundary area of the human β-globin locus control region exhibits silencer activity in erythroid cells

Ramchandran, R., Bengra, C., Whitney, B., Lanclos, K. & Tuan, D., Jan 1 2000, In : American Journal of Hematology. 65, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Adenovirus vector pseudotyping in fiber-expressing cell lines: Improved transduction of Epstein-Barr virus-transformed B cells

Von Seggern, D. J., Huang, S., Fleck, S. K., Stevenson, S. C. & Nemerow, G. R., Jan 1 2000, In : Journal of Virology. 74, 1, p. 354-362 9 p.

Research output: Contribution to journalArticle

97 Scopus citations

A retrospective analysis of invasive Streptococcus pneumoniae infections in Trinidad.

Williams, K. P. & Monteil, M. A., Mar 2000, In : The West Indian medical journal. 49, 1, p. 61-64 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cell growth and matrix invasion of EBV-immortalized human B lymphocytes is regulated by expression of α(v) integrins

Huang, S., Stupack, D., Liu, A., Cheresh, D. & Nemerow, G. R., Apr 6 2000, In : Oncogene. 19, 15, p. 1915-1923 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Characterization of [Re2Cl3(μ-dppm)2(NCCH3) 2][Cl] and [Re2Cl3(μ-dppm)2(NCC6H 5)2][Cl] · 2CH2Cl2 by X-ray Crystallographic and Two-Dimensional NMR Spectroscopic Techniques

Concolino, T. E., Eglin, J. L., Hadden, C. E., Hicks, R. P., Staples, R. J., Valente, E. J. & Zubkowski, J. D., Jan 1 2000, In : Journal of Cluster Science. 11, 1, p. 109-123 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cloning and functional characterization of a Na+-independent, broad-specific neutral amino acid transporter from mammalian intestine

Rajan, D. P., Kekuda, R., Huang, W., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jan 15 2000, In : Biochimica et Biophysica Acta - Biomembranes. 1463, 1, p. 6-14 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta

Wang, H., Huang, W., Sugawara, M., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jul 14 2000, In : Biochemical and Biophysical Research Communications. 273, 3, p. 1175-1179 5 p.

Research output: Contribution to journalArticle

87 Scopus citations

Descriptive epidemiology of asthma in Trinidad, West Indies

Monteil, M. A., Juman, S., Hassanally, R., Williams, K. P., Pierre, L., Rahaman, M., Singh, H. & Trinidade, A., Jan 1 2000, In : Journal of Asthma. 37, 8, p. 677-684 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Diagnosis and characterization of acute erythroleukemia subsets by determining the percentages of myeloblasts and proerythroblasts in 69 cases

Ramchandran, R., Bengra, C., Whitney, B., Lanclos, K. & Tuan Lo, D., Sep 11 2000, In : American Journal of Hematology. 65, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Differential influence of the 4F2 heavy chain and the protein related to b0,+ amino acid transport on substrate affinity of the heteromeric b0,+ amino acid transporter

Rajan, D. P., Huang, W., Kekuda, R., George, R. L., Wang, J., Conway, S. J., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., May 12 2000, In : Journal of Biological Chemistry. 275, 19, p. 14331-14335 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Electrogenic nature of rat sodium-dependent multivitamin transport

Prasad, P. D., Srinivas, S. R., Wang, H., Leibach, F. H., Devoe, L. D. & Ganapathy, V., Apr 21 2000, In : Biochemical and Biophysical Research Communications. 270, 3, p. 836-840 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Examination of the activity of carboxyl-terminal chimeric constructs of human and yeast ferrochelatases

Medlock, A. E. & Dailey, H. A., Jun 27 2000, In : Biochemistry. 39, 25, p. 7461-7467 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor α in mammalian retinal pigment epithelium

Chancy, C. D., Kekuda, R., Huang, W., Prasad, P. D., Kuhnel, J. M., Sirotnak, F. M., Roon, P., Ganapathy, V. & Smith, S. B., Jul 7 2000, In : Journal of Biological Chemistry. 275, 27, p. 20676-20684 9 p.

Research output: Contribution to journalArticle

117 Scopus citations

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

Arthur, W. T., Petch, L. A. & Burridge, K., Jun 1 2000, In : Current Biology. 10, 12, p. 719-722 4 p.

Research output: Contribution to journalArticle

362 Scopus citations

PKCε modulates NF-κB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes

Li, R. C. X., Ping, P., Zhang, J., Wead, W. B., Cao, X., Gao, J., Zheng, Y., Huang, S., Han, J. & Bolli, R., Jan 1 2000, In : American Journal of Physiology - Heart and Circulatory Physiology. 279, 4 48-4, p. H1679-H1689

Research output: Contribution to journalArticle

110 Scopus citations

Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A

Hatanaka, T., Huang, W., Wang, H., Sugawara, M., Prasad, P. D., Leibach, F. H. & Ganapathy, V., Jul 31 2000, In : Biochimica et Biophysica Acta - Biomembranes. 1467, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

112 Scopus citations

Primary structure genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+ - and H+ -coupled glutamine transporter

Fei, Y. J., Sugawara, M., Nakanishi, T., Huang, W., Wang, H., Prasad, P. D., Leibach, F. H. & Ganapathy, V., Aug 4 2000, In : Journal of Biological Chemistry. 275, 31, p. 23707-23717 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

Proteolytic cleavage of the Fe - S subunit hinge region of Rhodobacter capsulatus bc1 complex: Effects of inhibitors and mutations

Valkova-Valchanova, M., Darrouzet, E., Moomaw, C. R., Slaughter, C. A. & Daldal, F., Dec 19 2000, In : Biochemistry. 39, 50, p. 15484-15492 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Ras-independent oncogenic transformation by an EGF-receptor mutant

Boerner, J. L., McManus, M. J., Martin, G. S. & Maihle, N. J., Apr 12 2000, In : Journal of Cell Science. 113, 6, p. 935-942 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Solution structures in SDS micelles and functional activity at the bullfrog substance P receptor of ranatachykinin peptides

Perrine, S. A., Whitehead, T. L., Hicks, R. P., Szarek, J. L., Krause, J. E. & Simmons, M. A., May 30 2000, In : Journal of Medicinal Chemistry. 43, 9, p. 1741-1753 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Stable and unstable transgene integration sites in the human genome: extinction of the Green Fluorescent Protein transgene in K562 cells

Migliaccio, A. R., Bengra, C., Ling, J., Pi, W., Li, C., Zeng, S., Keskintepe, M., Whitney, B., Sanchez, M., Migliaccio, G. & Tuan, D., Oct 3 2000, In : Gene. 256, 1-2, p. 197-214 18 p.

Research output: Contribution to journalArticle

35 Scopus citations

The alloreactive and self-restricted CD4+ T cell response directed against a single MHC class II/peptide combination

Kovalik, J. P., Singh, N., Mendiratta, S. K., Martin, W. D., Ignatowicz, L. & Van Kaer, L., Aug 1 2000, In : Journal of Immunology. 165, 3, p. 1285-1293 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

The application of multidimensional NMR to the study of soil humic substances

Kingery, W. L., Simpson, A. J., Hayes, M. H. B., Locke, M. A. & Hicks, R. P., Jun 2000, In : Soil Science. 165, 6, p. 483-494 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

The protein tyrosine phosphatase Shp-2 regulates RhoA activity

Schoenwaelder, S. M., Petch, L. A., Williamson, D., Shen, R., Feng, G. S. & Burridge, K., Nov 30 2000, In : Current Biology. 10, 23, p. 1523-1526 4 p.

Research output: Contribution to journalArticle

116 Scopus citations

Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38α mitogen-activated protein kinase activity

Huang, S., New, L., Pan, Z., Han, J. & Nemerow, G. R., Apr 21 2000, In : Journal of Biological Chemistry. 275, 16, p. 12266-12272 7 p.

Research output: Contribution to journalArticle

120 Scopus citations

Various imaging modalities for the detection of salivary gland lesions: the advantages of tl spet

Arbab, A. S., Koizumi, K., Toyama, K., Nambu, A., Ichikawa, T., Arai, T. & Araki, T., Mar 2000, In : Nuclear Medicine Communications. 21, 3, p. 277-284 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
1999

A preliminary study of neopterin as a potential marker for severe dengue virus infection

Babb, K., Carrington, C. V. F. & Monteil, M. A., Jan 1 1999, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 93, 4, p. 447-448 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

A single amino acid in the adenovirus type 37 fiber confers binding to human conjunctival cells

Huang, S., Reddy, V., Dasgupta, N. & Nemerow, G. R., Apr 1999, In : Journal of Virology. 73, 4, p. 2798-2802 5 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta

Kenney, S. P., Kekuda, R., Prasad, P. D., Leibach, F. H., Devoe, L. D. & Ganapathy, V., Jan 1 1999, In : American Journal of Obstetrics and Gynecology. 181, 2, p. 491-497 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Characterization of the Moraxella catarrhalis uspA1 and uspA2 genes and their encoded products

Cope, L. D., Lafontaine, E. R., Slaughter, C. A., Hasemann, C. A., Aebi, C., Henderson, F. W., McCracken, G. H. & Hansen, E. J., Jul 1999, In : Journal of Bacteriology. 181, 13, p. 4026-4034 9 p.

Research output: Contribution to journalArticle

Open Access
87 Scopus citations

Cloning and expression of a b0,+-like amino acid transporter functioning asa heterodimer with 4F2hc-instead of rBAT. A new candidate gene for cystinuria

Rajan, D. P., Kekuda, R., Huang, W., Wang, H., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Oct 8 1999, In : Journal of Biological Chemistry. 274, 41, p. 29005-29010 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Cloning of the human thiamine transporter, a member of the folate transporter family

Dutta, B., Huang, W., Molero, M., Kekuda, R., Leibach, F. H., Devoe, L. D., Ganapathy, V. & Prasad, P. D., Nov 5 1999, In : Journal of Biological Chemistry. 274, 45, p. 31925-31929 5 p.

Research output: Contribution to journalArticle

141 Scopus citations

Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes

Liu, K., Schoonmaker, M. M., Levine, B. L., June, C. H., Hodes, R. J. & Weng, N. P., Apr 27 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 9, p. 5147-5152 6 p.

Research output: Contribution to journalArticle

198 Scopus citations

Contributions of viral splice sites and cis-regulatory elements to lentivirus vector function

Cui, Y., Iwakuma, T. & Chang, L. J., Jun 23 1999, In : Journal of Virology. 73, 7, p. 6171-6176 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Drugs of abuse and placental transport

Ganapathy, V., Prasad, P. D., Ganapathy, M. E. & Leibach, F. H., Jun 14 1999, In : Advanced Drug Delivery Reviews. 38, 1, p. 99-110 12 p.

Research output: Contribution to journalArticle

52 Scopus citations

Dynamic 99tcm-ecd spet correlates well with 201tl indices in brain tumours

Miyazawa, N., Koizumi, K., Arbab, A. S. & Tohyama, K., Nov 1999, In : Nuclear Medicine Communications. 20, 11, p. 1023-1030 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Dynamic SPET parameters of 123I-MIBG cardiac imaging

Arbab, A. S., Koizumi, K., Toyama, K., Arai, T. & Araki, T., Jul 1999, In : Nuclear Medicine Communications. 20, 7, p. 617-622 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system

Chang, L. J., Urlacher, V., Iwakuma, T., Cui, Y. & Zucali, J., May 1 1999, In : Gene Therapy. 6, 5, p. 715-728 14 p.

Research output: Contribution to journalArticle

174 Scopus citations

Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter

Wu, X., Huang, W., Prasad, P. D., Seth, P., Rajan, D. P., Leibach, F. H., Chen, J., Conway, S. J. & Ganapathy, V., Sep 1 1999, In : Journal of Pharmacology and Experimental Therapeutics. 290, 3, p. 1482-1492 11 p.

Research output: Contribution to journalArticle

292 Scopus citations

Human LAT1, a subunit of system L amino acid transporter: Molecular cloning and transport function

Prasad, P. D., Wang, H., Huang, W., Kekuda, R., Rajan, D. P., Leibach, F. H. & Ganapathy, V., Feb 16 1999, In : Biochemical and Biophysical Research Communications. 255, 2, p. 283-288 6 p.

Research output: Contribution to journalArticle

173 Scopus citations

Human Na+-dependent vitamin C transporter 1 (hSVCT1): Primary structure, functional characteristics and evidence for a non-functional splice variant

Wang, H., Dutta, B., Huang, W., Devoe, L. D., Leibach, F. H., Ganapathy, V. & Prasad, P. D., Nov 9 1999, In : Biochimica et Biophysica Acta - Biomembranes. 1461, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

109 Scopus citations

Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, chromosomal localization

Wang, H., Huang, W., Fei, Y. J., Xia, H., Yang-Feng, T. L., Leibach, F. H., Devoe, L. D., Ganapathy, V. & Prasad, P. D., May 21 1999, In : Journal of Biological Chemistry. 274, 21, p. 14875-14883 9 p.

Research output: Contribution to journalArticle

114 Scopus citations

Human placental sodium-dependent vitamin C transporter (SVCT2): Molecular cloning and transport function

Rajan, D. P., Huang, W., Dutta, B., Devoe, L. D., Leibach, F. H., Ganapathy, V. & Prasad, P. D., Sep 7 1999, In : Biochemical and Biophysical Research Communications. 262, 3, p. 762-768 7 p.

Research output: Contribution to journalArticle

132 Scopus citations

Intrastrain variants of herpes simplex virus type 1 isolated from a neonate with fatal disseminated infection differ in the ICP34.5 gene, glycoprotein processing, and neuroinvasiveness

Bower, J. R., Hanwen, M., Durishin, C., Rozenbom, E., Detwiler, M., Rempinski, D., Karban, T. L. & Rosenthal, K. S., Jan 1 1999, In : Journal of Virology. 73, 5, p. 3843-3853 11 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

Molecular and functional characterization of the intestinal Na+- dependent multivitamin transporter

Prasad, P. D., Wang, H., Huang, W., Fei, Y. J., Leibach, F. H., Devoe, L. D. & Ganapathy, V., Jun 1 1999, In : Archives of Biochemistry and Biophysics. 366, 1, p. 95-106 12 p.

Research output: Contribution to journalArticle

99 Scopus citations

Molecular and ligand-binding characterization of the σ-receptor in the Jurkat human T lymphocyte cell line

Ganapathy, M. E., Prasad, P. D., Huang, W., Seth, P., Leibach, F. H. & Ganapathy, V., Apr 1999, In : Journal of Pharmacology and Experimental Therapeutics. 289, 1, p. 251-260 10 p.

Research output: Contribution to journalArticle

93 Scopus citations