Biochemistry and Molecular Biology

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1992
13 Citations (Scopus)

Autophosphorylation of Skeletal Muscle Myosin Light Chain Kinase

Gao, Z. H., Stull, J. T., Moomaw, C. R., Hsu, J. & Slaughter, C. A., Feb 1 1992, In : Biochemistry. 31, 26, p. 6126-6133 8 p.

Research output: Contribution to journalArticle

Skeletal Muscle Myosins
Myosin-Light-Chain Kinase
Calmodulin
Phosphorylation
Catalytic Domain
1 Citation (Scopus)

Complete distal renal tubular acidosis: Biochemical profile of a case

Rajpurohit, S. K., Pendse, AK., Ahmed, A. & Singh, PP., 1992, In : Indian Journal of Clinical Biochemistry. 7, 2, p. 205-206 2 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Conformational analysis of met‐enkephalin in both aqueous solution and in the presence of sodium dodecyl sulfate micelles using multidimensional NMR and molecular modeling

Graham, W. H., Carter, E. S. & Hicks, R. P., Jan 1 1992, In : Biopolymers. 32, 12, p. 1755-1764 10 p.

Research output: Contribution to journalArticle

Molecular modeling
Sodium dodecyl sulfate
Micelles
Sodium Dodecyl Sulfate
Conformations
31 Citations (Scopus)

Identification and Localization of a Cysteinyl Residue Critical for the Trypsin-like Catalytic Activity of the Proteasome

Dick, L. R., Moomaw, C. R., Pramanik, B. C., DeMartino, G. N. & Slaughter, C. A., Feb 1 1992, In : Biochemistry. 31, 32, p. 7347-7355 9 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Trypsin
Catalyst activity
Peptide Hydrolases
Amino Acids
249 Citations (Scopus)

Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor

Lust, J. A., Donovan, K. A., Kline, M. P., Greipp, P. R., Kyle, R. A. & Maihle, N. J., Mar 1992, In : Cytokine. 4, 2, p. 96-100 5 p.

Research output: Contribution to journalArticle

Interleukin-6 Receptors
Messenger RNA
Sequence Analysis
B-Lymphocytes
Interleukin-7 Receptors
47 Citations (Scopus)

Proliferation of human colon cancer cells: Role of epidermal growth factor and transforming growth factorα

Huang, S., Trujillo, J. M. & Chakrabarty, S., Dec 2 1992, In : International Journal of Cancer. 52, 6, p. 978-986 9 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Epidermal Growth Factor
Colonic Neoplasms
Cell Line
Intercellular Signaling Peptides and Proteins
40 Citations (Scopus)

Signals from focal adhesions

Burridge, K., Petch, L. A. & Romer, L. H., Oct 1992, In : Current Biology. 2, 10, p. 537-539 3 p.

Research output: Contribution to journalArticle

Focal Adhesions
adhesion
25 Citations (Scopus)

Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles: Transport and binding

Prasad, P. D., Leibach, F. H., Mahesh, V. B. & Ganapathy, V., Nov 25 1992, In : Journal of Biological Chemistry. 267, 33, p. 23632-23639 8 p.

Research output: Contribution to journalArticle

Antiporters
Transport Vesicles
Brushes
Microvilli
Cations
39 Citations (Scopus)

The interactions of neuropeptides with membrane model systems: A case study

Hicks, R. P., Beard, D. J. & Young, J. K., Jan 1992, In : Biopolymers. 32, 1, p. 85-96 12 p.

Research output: Contribution to journalArticle

Bradykinin
Substance P
Neuropeptides
Membranes
Lysophosphatidylcholines
16 Citations (Scopus)

The use of UV‐visible spectroscopy for the determination of hydrophobic interactions between neuropeptides and membrane model systems

Young, J. K., Graham, W. H., Beard, D. J. & Hicks, R. P., Aug 1992, In : Biopolymers. 32, 8, p. 1061-1064 4 p.

Research output: Contribution to journalArticle

Lysophosphatidylcholines
Rabies
Sodium dodecyl sulfate
Micelles
Bradykinin
133 Citations (Scopus)

Transcription of the hypersensitive site HS2 enhancer in erythroid cells

Tuan, D., Kong, S. & Hu, K., Dec 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 23, p. 11219-11223 5 p.

Research output: Contribution to journalArticle

Erythroid Cells
Chloramphenicol O-Acetyltransferase
Genes
RNA
Globins
1991
46 Citations (Scopus)

1,3,8-Trisubstituted Xanthines. Effects of Substitution Pattern upon Adenosine Receptor A1/A2 Affinity

Erickson, R. H., Hiner, R. N., Feeney, S. W., Blake, P. R., Rzeszotarski, W. J., Hicks, R. P., Costello, D. G. & Abreu, M. E., Apr 1 1991, In : Journal of Medicinal Chemistry. 34, 4, p. 1431-1435 5 p.

Research output: Contribution to journalArticle

Xanthines
Adenosine A2 Receptors
Adenosine A1 Receptors
varespladib methyl
62 Citations (Scopus)

Characterization of progesterone receptor binding to the 90- and 70- kDa heat shock proteins

Schowalter, D. B., Sullivan, W. P., Maihle, N. J., Dobson, A. D. W., Conneely, O. M., O'Malley, B. W. & Toft, D. O., Jan 1 1991, In : Journal of Biological Chemistry. 266, 31, p. 21165-21173 9 p.

Research output: Contribution to journalArticle

HSP70 Heat-Shock Proteins
Progesterone Receptors
Steroids
Chickens
Cells
48 Citations (Scopus)

Cloning of murine tissue factor and regulation of gene expression by transforming growth factor type β1

Ranganathan, G., Blatti, S. P., Subramaniam, M., Fass, D. N., Maihle, N. J. & Getz, M. J., Jan 31 1991, In : Journal of Biological Chemistry. 266, 1, p. 496-501 6 p.

Research output: Contribution to journalArticle

Cloning
Gene Expression Regulation
Thromboplastin
Transforming Growth Factors
Gene expression
82 Citations (Scopus)

Degradation of Oxidized Insulin B Chain by the Multiproteinase Complex Macropain (Proteasome)

Dick, L. R., Moomaw, C. R., DeMartino, G. N. & Slaughter, C. A., Mar 1 1991, In : Biochemistry. 30, 10, p. 2725-2734 10 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Insulin
Degradation
Peptides
Antipain
20 Citations (Scopus)

Growth modulation by epidermal growth factor (EGF) in human colonic carcinoma cells: Constitutive expression of the human EGF gene

Huang, S., Lin, PF. F., Fan, D., Price, J. E., Trujillo, J. M. & Chakrabarty, S., Aug 1991, In : Journal of Cellular Physiology. 148, 2, p. 220-227 8 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Genes
Cells
Modulation
Carcinoma
22 Citations (Scopus)

Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor

Maihle, N. J., Flickinger, T. W., Raines, M. A., Sanders, M. L. & Kung, H. J., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 5, p. 1825-1829 5 p.

Research output: Contribution to journalArticle

erbB Genes
Immune Sera
Ligands
Growth Factor Receptors
Proteins
1990
171 Citations (Scopus)

A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue

Petch, L. A., Harris, J., Raymond, V. W., Blasband, A., Lee, D. C. & Earp, H. S., Jan 1 1990, In : Molecular and Cellular Biology. 10, 6, p. 2973-2982 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Messenger RNA
Clone Cells
Epidermal Growth Factor
Hepatocytes
4 Citations (Scopus)

NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays

Kaplita, P. V., Abreu, M. E., Connor, J. R., Erickson, R. H., Ferkany, J. W., Hicks, R. P., Schenden, J. A., Noronha‐Blob, L. & Hanson, R. C., 1990, In : Drug Development Research. 20, 4, p. 429-443 15 p.

Research output: Contribution to journalArticle

Adenosine A1 Receptor Antagonists
Xanthine
Guinea Pigs
Adenylyl Cyclases
Adenosine A2 Receptors

Retroviral insertional mutagenesis: the making of a receptor-oncogene.

Kung, H. J., Pelley, R. J., Shu, H. K., Maihle, N. J., Raines, M., Carter, T., Boerkoel, C., Moscovici, G. & Moscovici, C., Jan 1 1990, In : Developments in biological standardization. 72, p. 139-144 6 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Avian Leukosis Virus
Leukemia, Erythroblastic, Acute
Insertional Mutagenesis
Viral DNA
8 Citations (Scopus)

Staphylococcal opsonization and anti-Staphylococcus aureus IgG subclass antibodies in patients with severe or recurrent S. aureus infections

Monteil, M. A., Kaniuk, A. S. C. & Hobbs, J. R., Dec 1990, In : FEMS Microbiology Letters. 64, 5-6, p. 259-262 4 p.

Research output: Contribution to journalArticle

Staphylococcus aureus
Immunoglobulin G
Antibodies
Infection
Staphylococcal Infections
1989
199 Citations (Scopus)

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human 'β-like globin' genes

Tuan, D. Y. H., Solomon, W. B., London, I. M. & Lee, D. P., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 8, p. 2554-2558 5 p.

Research output: Contribution to journalArticle

Globins
Genes
Erythroid Cells
Genetic Complementation Test
16 Citations (Scopus)

Disease tropism of c-erbB: Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation

Pelley, R. J., Maihle, N. J., Boerkoel, C., Shu, H. K., Carter, T. H., Moscovici, C. & Kung, H. J., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 18, p. 7164-7168 5 p.

Research output: Contribution to journalArticle

Tropism
Tyrosine
Phosphotransferases
Avian Leukosis Virus
Leukemia, Erythroblastic, Acute
9 Citations (Scopus)

One hundred years of retinoblastoma Research: From the clinic to the gene and back again

Cowell, J. K., Jun 1 1989, In : Ophthalmic Paediatrics and Genetics. 10, 2, p. 75-88 14 p.

Research output: Contribution to journalArticle

Retinoblastoma
Research
Genes
Neoplasms
Chromosomes, Human, Pair 13
1988
60 Citations (Scopus)

Epidermal growth factor (EGF) and hormones stimulate phosphoinositide hydrolysis and increase EGF receptor protein synthesis and mRNA levels in rat liver epithelial cells. Evidence for protein kinase C-dependent and -independent pathways

Earp, H. S., Hepler, J. R., Petch, L. A., Miller, A., Berry, A. R., Harris, J. A., Raymond, V. W., McCune, B. K., Lee, L. W., Grisham, J. W. & Harden, T. K., Jan 1 1988, In : Journal of Biological Chemistry. 263, 27, p. 13868-13874 7 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Epidermal Growth Factor Receptor
Epidermal Growth Factor
Liver
Protein Kinase C
135 Citations (Scopus)

Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Gil, G., Smith, J. R., Goldstein, J. L., Slaughter, C. A., Orth, K., Brown, M. S. & Osborn, T. F., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 23, p. 8963-8967 5 p.

Research output: Contribution to journalArticle

NFI Transcription Factors
Oxidoreductases
Genes
Proteins
Cricetinae
24 Citations (Scopus)

Proviral insertional activation of c-erbB: Differential processing of the protein products arising from two alternate transcripts

Maihle, N. J., Raines, M. A., Flickinger, T. W. & Kung, H. J., Jan 1 1988, In : Molecular and Cellular Biology. 8, 11, p. 4868-4876 9 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins
Genetic Transcription
Genetic Transformation
Proviruses
Proto-Oncogenes
23 Citations (Scopus)

Septic scarlet fever due to streptococcus pyogenes cellulitis

Shaunak, S., Wendon, J., Monteil, M. & Gordon, A. M., Nov 1988, In : QJM. 69, 2, p. 921-925 5 p.

Research output: Contribution to journalArticle

Scarlet Fever
Cellulitis
Streptococcus pyogenes
Toxemia
Young Adult
1987
56 Citations (Scopus)

Application of a protein-blotting procedure to the study of human glucocorticoid receptor interactions with DNA

Silva, C. M., Tully, D. B., Petch, L. A., Jewell, C. M. & Cidlowski, J. A., Jun 11 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 7, p. 1744-1748 5 p.

Research output: Contribution to journalArticle

Glucocorticoid Receptors
Mouse mammary tumor virus
DNA
Proteins
Collodion
14 Citations (Scopus)

SELECTIVE IMMUNODEFICIENCY AFFECTING STAPHYLOCOCCAL RESPONSE

Monteil, M., Hobbs, J. & Citron, K., Oct 17 1987, In : The Lancet. 330, 8564, p. 880-883 4 p.

Research output: Contribution to journalArticle

Immunoglobulin G
Staphylococcal Infections
Sepsis
Antibodies
Therapeutics
1986
3 Citations (Scopus)

Blood utilization for elective general surgery at the Port-of-Spain General Hospital.

Monteil, M. A. & Naraynsingh, V., Dec 1 1986, In : West Indian Medical Journal. 35, 4, p. 293-294 2 p.

Research output: Contribution to journalArticle

Hospital Surgery Department
Blood Grouping and Crossmatching
Trinidad and Tobago
Blood Banks
Hospital Departments
61 Citations (Scopus)

Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids

Henthorn, P. S., Knoll, B. J., Raducha, M., Rothblum, K. N., Slaughter, C. A., Weiss, M., Lafferty, M. A., Fischer, T. & Harris, H., Dec 19 1986, In : Proceedings of the National Academy of Sciences of the United States of America. 83, 15, p. 5597-5601 5 p.

Research output: Contribution to journalArticle

Amino Acid Sequence
Complementary DNA
Alleles
Amino Acids
Gene Library
1985
63 Citations (Scopus)

Agonist-induced alteration in the membrane form of muscarinic cholinergic receptors

Harden, T. K., Petch, L. A., Traynelis, S. F. & Waldo, G. L., Dec 1 1985, In : Journal of Biological Chemistry. 260, 24, p. 13060-13066 7 p.

Research output: Contribution to journalArticle

Cholinergic Receptors
Muscarinic Receptors
Cholinergic Agents
Carbachol
Membranes

Agonist-induced change in the membrane form of muscarinic cholinergic receptors (MR) in astrocytoma cells

Harden, T. K., Petch Lee, L. A. & Traynelis, S. F., Jan 1 1985, In : Federation Proceedings. 44, 5

Research output: Contribution to journalArticle

Astrocytoma
Cholinergic Receptors
Muscarinic Receptors
Membranes
7 Citations (Scopus)

Preparation of glucosidic derivatives of steganol

Hicks, R. P. & Sneden, A. T., Jan 1 1985, In : Journal of Natural Products. 48, 3, p. 357-362 6 p.

Research output: Contribution to journalArticle

Glucosides
Derivatives
Podophyllotoxin
Acetaldehyde
Assays
28 Citations (Scopus)

Protein secretion in Tetrahymena thermophila: Characterization of the secretory mutant strain SB281

Maihle, N. J. & Satir, B. H., Jan 1 1985, In : Journal of Cell Science. VOL. 78, p. 49-65 17 p.

Research output: Contribution to journalArticle

Freeze Fracturing
Tetrahymena thermophila
Tetrahymena
Species Specificity
Membrane Fusion
412 Citations (Scopus)

The 'β-like-globin' gene domain in human erythroid cells

Tuan Lo, D., Solomon, W., Li, Q. & London, I. M., Jan 1 1985, In : Proceedings of the National Academy of Sciences of the United States of America. 82, 19, p. 6384-6388 5 p.

Research output: Contribution to journalArticle

Erythroid Cells
Globins
Deoxyribonuclease I
Genes
DNA
1984
80 Citations (Scopus)
Globins
K562 Cells
Deoxyribonuclease I
Leukemia
myc Genes
15 Citations (Scopus)

Neoisostegane, A New Bisbenzocyclooctadiene Lignan Lactone from Steganotaenia Araliacea1

Taafrout, M., Rouessac, F., Robin, J. P., Hicks, R. P., Shillady, D. D. & Sneden, A. T., May 1984, In : Journal of Natural Products. 47, 4, p. 600-606 7 p.

Research output: Contribution to journalArticle

Lignans
Lactones
Araliaceae
Isomerization
Functional groups
1983
83 Citations (Scopus)

cDNA cloning of the bovine low density lipoprotein receptor: Feedback regulation of a receptor mRNA

Russell, D. W., Yamamoto, T., Schneider, W. J., Slaughter, C. A., Brown, M. S. & Goldstein, J. L., Jan 1 1983, In : Proceedings of the National Academy of Sciences of the United States of America. 80, 24 I, p. 7501-7505 5 p.

Research output: Contribution to journalArticle

LDL Receptors
Organism Cloning
Complementary DNA
Messenger RNA
Cyanogen Bromide
3 Citations (Scopus)

Molecular studies of mutations that increase Hb F production in man.

Forget, B. G., Tuan Lo, D., Newman, M. V., Feingold, E. A., Collins, F., Fukumaki, Y., Jagadeeswaran, P. & Weissman, S. M., Dec 1 1983, In : Progress in clinical and biological research. 134, p. 65-76 12 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Chromosome Deletion
Thalassemia
Chromosome Mapping
Gene Expression Regulation
20 Citations (Scopus)

Neoisostegane, a new bisbenzocyclooctadiene lignan lactone from Steganotaenia araliacea hochst.

Hicks, R. P. & Sneden, A. T., Jan 1 1983, In : Tetrahedron Letters. 24, 29, p. 2987-2990 4 p.

Research output: Contribution to journalArticle

Araliaceae
Lignans
Lactones
Nuclear magnetic resonance
Proton Magnetic Resonance Spectroscopy
1982
64 Citations (Scopus)

A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin

Jagadeeswaran, P., Tuan, D., Forget, B. G. & Weissman, S. M., Dec 1 1982, In : Nature. 296, 5856, p. 469-470 2 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Nucleic Acid Repetitive Sequences
Gene Deletion
Globins
Genes
1981
56 Citations (Scopus)

Calmodulin localization during capping and receptor-mediated endocytosis

Salisbury, J. L., Condeelis, J. S., Maihle, N. J. & Satir, P., Dec 1 1981, In : Nature. 294, 5837, p. 163-166 4 p.

Research output: Contribution to journalArticle

Receptor Aggregation
Calmodulin
Endocytosis
Trifluoperazine
Ligands
31 Citations (Scopus)

Presence and indirect immunofluorescent localization of calmodulin in Paramecium tetraurelia

Maihle, N. I., Dedman, J. R., Means, A. R., Chafouleas, J. G. & Satir, B. H., Oct 19 1981, In : Journal of Cell Biology. 89, 3, p. 695-699 5 p.

Research output: Contribution to journalArticle

Paramecium tetraurelia
Organoids
Paramecium
Calcium-Binding Proteins
Cilia
13 Citations (Scopus)

Ultrastructure of the flagellar apparatus of the green alga Tetraselmis subcordiformis - With special consideration given to the function of the rhizoplast and rhizanchora

Salisbury, J. L., Swanson, J. A., Floyd, G. L., Hall, R. & Maihle, N. J., Mar 1 1981, In : Protoplasma. 107, 1-2, p. 1-11 11 p.

Research output: Contribution to journalArticle

Basal Bodies
Tetraselmis
Chlorophyta
microtubules
ultrastructure
1980

ANALYSIS OF β‐GLOBIN GENES IN β^ THALASSEMIA

Tuan, D., Biro, P. A., De Riel, J. K. & Forget, B. G., May 1980, In : Annals of the New York Academy of Sciences. 344, 1, p. 12-30 19 p.

Research output: Contribution to journalArticle

Genetic Suppression
Nucleic Acid Hybridization
Chromosome Deletion
Thalassemia
Globins
20 Citations (Scopus)

Cotransfer of circular and linear prokaryotic and eukaryotic DNA sequences into mouse cells.

Hsiung, N., Warrick, H., deRiel, J. K., Tuan, D., Forget, B. G., Skoultchi, A. & Kucherlapati, R., Aug 1980, In : Proceedings of the National Academy of Sciences of the United States of America. 77, 8, p. 4852-4856 5 p.

Research output: Contribution to journalArticle

Thymidine Kinase
Plasmids
Genes
beta-Globins
Transfection
42 Citations (Scopus)

Heterogeneity in the molecular basis of hereditary persistence of fetal haemoglobin

Tuan Lo, D., Murnane, M. J., DeRiel, J. K. & Forget, B. G., Dec 1 1980, In : Nature. 285, 5763, p. 335-337 3 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Globins
Gene Deletion
DNA
Hemoglobins
13 Citations (Scopus)

Morphological and ultrastructural features of Nikitinsporites canadensis chaloner, a devonian megaspore from the frasnian of canada

Taylor, T. N., Maihle, N. J. & Hills, L. V., Jan 1 1980, In : Review of Palaeobotany and Palynology. 30, C, p. 89-99 11 p.

Research output: Contribution to journalArticle

megaspores
Frasnian
ornamentation
ultrastructure
appendages