Biochemistry and Molecular Biology

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Synergistic activation of NF-κB by bacterial chemoattractant and TNFα is mediated by p38 MAPK-dependent RelA acetylation

Pan, W. W., Li, J. D., Huang, S., Papadimos, T. J., Pan, Z. K. & Chen, L. Y., Nov 5 2010, In : Journal of Biological Chemistry. 285, 45, p. 34348-34354 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Synergistic induction of inflammation by bacterial products lipopolysaccharide and fMLP: An important microbial pathogenic mechanism

Chen, L. Y., Pan, W. W., Chen, M., Li, J. D., Liu, W., Chen, G., Huang, S., Papadimos, T. J. & Pan, Z. K., Feb 15 2009, In : Journal of Immunology. 182, 4, p. 2518-2524 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Synergistic Targeting HER2 and EGFR with Bivalent Aptamer-siRNA Chimera Efficiently Inhibits HER2-Positive Tumor Growth

Xue, L., Maihle, N. J., Yu, X., Tang, S. C. & Liu, H., Nov 5 2018, In : Molecular Pharmaceutics. 15, 11, p. 4801-4813 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Synthesis, characterization, DNA binding and cytotoxicity studies of moxifloxacinato complexes

Singh, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Chakraborty, D., Sep 1 2012, In : Transition Metal Chemistry. 37, 6, p. 541-551 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Synthesis, DNA binding and antiproliferative activity of ternary copper complexes of moxifloxacin and gatifloxacin against lung cancer cells

Singh, R., Jadeja, R. N., Thounaojam, M. C., Patel, T., Devkar, R. V. & Chakraborty, D., Sep 1 2012, In : Inorganic Chemistry Communications. 23, p. 78-84 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Synthesis of radioactive single-stranded DNA probes using asymmetrical PCR and oligonucleotide random priming

Mao, H. & Rosenthal, K. S., 1999, In : BioTechniques. 27, 4, p. 674-678 5 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Synthetic HLA-G proteins for therapeutic use in transplantation

LeMaoult, J., Daouya, M., Wu, J., Loustau, M., Horuzsko, A. & Carosella, E. D., Sep 1 2013, In : FASEB Journal. 27, 9, p. 3643-3651 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Systemic antibiotic therapy reduces circulating inflammatory dendritic cells and Treg–Th17 plasticity in periodontitis

Rajendran, M., Looney, S., Singh, N., Elashiry, M., Meghil, M. M., El-Awady, A. R., Tawfik, O., Susin, C., Arce, R. M. & Cutler, C. W., May 1 2019, In : Journal of Immunology. 202, 9, p. 2690-2699 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Systemic levels of estrogens and PGE2 synthesis in relation to postmenopausal breast cancer risk

Kim, S., Campbell, J., Yoo, W., Taylor, J. A. & Sandler, D. P., Mar 1 2017, In : Cancer Epidemiology Biomarkers and Prevention. 26, 3, p. 383-388 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

TAB1β (transforming growth factor-β-activated protein kinase 1-binding protein 1β), a novel splicing variant of TAB1 that interacts with p38α but not TAK1

Ge, B., Xiong, X., Jing, Q., Mosley, J. L., Filose, A., Bian, D., Huang, S. & Han, J., Jan 24 2003, In : Journal of Biological Chemistry. 278, 4, p. 2286-2293 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

TAK1 is required for TGF-β1-mediated regulation of matrix metalloproteinase-9 and metastasis

Safina, A., Ren, M. Q., Vandette, E. & Bakin, A. V., Feb 21 2008, In : Oncogene. 27, 9, p. 1198-1207 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing

Lee, E. J., Pei, L., Srivastava, G., Joshi, T., Kushwaha, G., Choi, J-H., Robertson, K. D., Wang, X., Colbourne, J. K., Zhang, L., Schroth, G. P., Xu, D., Zhang, K. & Shi, H., Oct 1 2011, In : Nucleic Acids Research. 39, 19

Research output: Contribution to journalArticle

44 Scopus citations

Targeted next generation sequencing approach identifies eighteen new candidate genes in normosmic hypogonadotropic hypogonadism and Kallmann syndrome

Quaynor, S. D., Bosley, M. E., Duckworth, C. G., Porter, K. R., Kim, S. H., Kim, H. G., Chorich, L. P., Sullivan, M. E., Choi, J. H., Cameron, R. S. & Layman, L. C., Dec 5 2016, In : Molecular and Cellular Endocrinology. 437, p. 86-96 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer

Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In : Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models

Wu, Q., Bhole, A., Qin, H., Karp, J., Malek, S., Cowell, J. K. & Ren, M., 2016, In : Oncotarget. 7, 31, p. 49733-49742 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia

Ganguly, S., Home, T., Yacoub, A., Kambhampati, S., Shi, H., Dandawate, P., Padhye, S., Saluja, A. K., McGuirk, J. & Rao, R., 2015, In : Oncotarget. 6, 31, p. 31767-31779 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Targeting hyaluronidase for cancer therapy: Antitumor activity of sulfated hyaluronic acid in prostate cancer cells

Benitez, A., Yates, T. J., Lopez, L. E., Cerwinka, W. H., Bakkar, A. & Lokeshwar, V. B., Jun 15 2011, In : Cancer Research. 71, 12, p. 4085-4095 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Targeting lymphotoxin β receptor with tumor-specific T lymphocytes for tumor regression

Yang, D., Ud Din, N., Browning, D. D., Abrams, S. I. & Liu, K., Sep 1 2007, In : Clinical Cancer Research. 13, 17, p. 5202-5210 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers

Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E., Melnik, M. K., Korkaya, H., Maroun, C. R., Christensen, J. G., Steensma, M. R., Boerner, J. L. & Graveel, C. R., Jan 1 2016, In : Oncotarget. 7, 43, p. 69903-69915 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress

Zhang, Y., Lai, J., Du, Z., Gao, J., Yang, S., Gorityala, S., Xiong, X., Deng, O., Ma, Z., Yan, C., Susana, G., Xu, Y. & Zhang, J., Jun 7 2016, In : Oncotarget. 7, 23, p. 34688-34702 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Targeting the MYC oncogene in burkitt lymphoma through HSP90 inhibition

Poole, C. J., Zheng, W., Lee, H., Young, D., Lodh, A., Chadli, A. & van Riggelen, J., Nov 16 2018, In : Cancers. 10, 11, 448.

Research output: Contribution to journalArticle

4 Scopus citations

Targeting the sodium-dependent multivitamin transporter (SMVT) for improving the oral absorption properties of a retro-inverso Tat nonapeptide

Ramanathan, S., Pooyan, S., Stein, S., Prasad, P. D., Wang, J., Leibowitz, M. J., Ganapathy, V. & Sinko, P. J., Sep 11 2001, In : Pharmaceutical Research. 18, 7, p. 950-956 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Tauroursodeoxycholic acid alleviates secondary injury in the spinal cord via up-regulation of CIBZ gene

Zhang, Z., Chen, J., Chen, F., Yu, D., Li, R., Lv, C., Wang, H., Li, H., Li, J. & Cai, Y., Jul 1 2018, In : Cell Stress and Chaperones. 23, 4, p. 551-560 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

T cells can be activated by peptides that are unrelated in sequence to their selecting peptide

Ignatowicz, L., Rees, W., Pacholczyk, R. W., Ignatowicz, H., Kushnir, E., Kappler, J. & Marrack, P., Jan 1 1997, In : Immunity. 7, 2, p. 179-186 8 p.

Research output: Contribution to journalArticle

105 Scopus citations

Teaching Biochemistry and Genetics to Students of Medicine, Pharmacy, and Dentistry: 6 th International Conference of the Association of Biochemistry Educators (ABE) Clearwater Beach, FL, USA, May 7-11, 2017

Niederhoffer, E. C., Cline, S. D., Osheroff, N., Simmons, J. M., Diekman, A. B., Franklin, D. S., Abali, E. E., Bateman, R. C., Fontes, J. D., Lindsley, J. E., Pearson, D., Rubenstein, P. A., Slaughter, C. A., Bernstein, J. A., Hyland, K. M., Park, V. M., Sobering, A. K., Weiler, T. A. & Dasgupta, S., Dec 1 2017, In : Medical Science Educator. 27, 4, p. 855-859 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Teaching Biochemistry to Students of Medicine, Pharmacy and Dentistry: 5th International Conference of the Association of Biochemistry Course Directors (ABCD) Santa Fe, NM, USA, May 3–7, 2015

Osheroff, N., Niederhoffer, E. C., Sabina, R. L., Cline, S. D., Wimmer, M. J., Franklin, D. S., Diekman, A. B., Hogg, T., Kearney, K. R., King, S. C., Pearson, D., Slaughter, C. A. & Thompson, K., Dec 1 2015, In : Medical Science Educator. 25, 4, p. 473-477 5 p.

Research output: Contribution to journalArticle

Technetium-99m-tetrofosmin, Technetium-99m-MIBI and Thallium-201 uptake in rat myocardial cells

Arbab, A. S., Koizumi, K., Toyama, K., Arai, T. & Araki, T., Feb 1 1998, In : Journal of Nuclear Medicine. 39, 2, p. 266-271 6 p.

Research output: Contribution to journalArticle

82 Scopus citations

Testosterone Affects Neural Gene Expression Differently in Male and Female Juncos: A Role for Hormones in Mediating Sexual Dimorphism and Conflict

Peterson, M. P., Rosvall, K. A., Choi, J. H., Ziegenfus, C., Tang, H., Colbourne, J. K. & Ketterson, E. D., Apr 16 2013, In : PloS one. 8, 4, e61784.

Research output: Contribution to journalArticle

37 Scopus citations

TGFbeta-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas

Müller, J., Samans, B., Van Riggelen, J., Fagà, G., Raquel Peh, K. N., Wei, C. L., Müller, H., Amati, B., Felsher, D. & Eilers, M., Dec 1 2010, In : Cell Cycle. 9, 23, p. 4622-4626 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

TGF-β signaling in myeloid cells is required for tumor metastasis

Pang, Y., Gara, S. K., Achyut, B. R., Li, Z., Yan, H. H., Day, C-P., Weiss, J. M., Trinchieri, G., Morris, J. C. & Yang, L., Aug 2013, In : Cancer Discovery. 3, 8, p. 936-51 16 p.

Research output: Contribution to journalArticle

58 Scopus citations

The 100 kDa haem:haemopexin‐binding protein of Haemophilus Influenzae: structure and localization

Cope, L. D., Thomas, S. E., Latimer, J. L., Slaughter, C. A., Müller‐Eberhard, U. & Hansen, E. J., Sep 1994, In : Molecular Microbiology. 13, 5, p. 863-873 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins

Wei, S., Wang, H., Lu, C., Malmut, S., Zhang, J., Ren, S., Yu, G., Wang, W., Tang, D. D. & Yan, C., Mar 30 2014, In : Journal of Biological Chemistry. 289, 13, p. 8947-8959 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

The alloreactive and self-restricted CD4+ T cell response directed against a single MHC class II/peptide combination

Kovalik, J. P., Singh, N., Mendiratta, S. K., Martin, W. D., Ignatowicz, L. & Van Kaer, L., Aug 1 2000, In : Journal of Immunology. 165, 3, p. 1285-1293 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
68 Scopus citations

The andean anticancer herbal product BIRM causes destabilization of androgen receptor and induces caspase-8 mediated-apoptosis in prostate cancer

Shamaladevi, N., Araki, S., Lyn, D. A., Ayyathurai, R., Gao, J., Lokeshwar, V. B., Navarrete, H. & Lokeshwar, B. L., 2016, In : Oncotarget. 7, 51, p. 84201-84213 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

The anthrax protective antigen (PA63) bound conformation of a peptide inhibitor of the binding of lethal factor to PA63: As determined by trNOESY NMR and molecular modeling

Hicks, R. P., Bhattacharjee, A. K., Koser, B. W. & Traficante, D. D., Oct 21 2004, In : Journal of Medicinal Chemistry. 47, 22, p. 5347-5355 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors

Pathania, A. S., Wani, Z. A., Guru, S. K., Kumar, S., Bhushan, S., Korkaya, H., Seals, D. F., Kumar, A., Mondhe, D. M., Ahmed, Z., Chandan, B. K. & Malik, F., Jan 21 2015, In : Molecular cancer. 14, 1, 6.

Research output: Contribution to journalArticle

17 Scopus citations

The application of DOSY NMR and molecular dynamics simulations to explore the mechanism(s) of micelle binding of antimicrobial peptides containing unnatural amino acids

Clark, T. D., Bartolotti, L. & Hicks, R. P., Aug 1 2013, In : Biopolymers. 99, 8, p. 548-561 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

The application of multidimensional NMR to the study of soil humic substances

Kingery, W. L., Simpson, A. J., Hayes, M. H. B., Locke, M. A. & Hicks, R. P., Jun 2000, In : Soil Science. 165, 6, p. 483-494 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

The association of dimethylsulfoxide and model membranes studied by pulse-field gradient NMR

Kennedy, A., Long, C. J., Hmel, P. J., Hicks, R. & Reid, T. J., 2004, In : Spectroscopy. 18, 2, p. 265-269 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

The association of elevated urinary total to sulfated glycosaminoglycan ratio and high molecular mass hyaluronic acid with interstitial cystitis

Wei, D. C., Politano, V. A., Selzer, M. G. & Lokeshwar, V. B., May 2000, In : Journal of Urology. 163, 5, p. 1577-1583 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

The biology of isolated chromatin

Bonner, J., Dahmus, M. E., Fambrough, D., Huang, R. C. C., Marushige, K. & Tuan, D. Y. H., Jan 1 1968, In : Science. 159, 3810, p. 47-56 10 p.

Research output: Contribution to journalArticle

273 Scopus citations

The cell polarity protein Scrib functions as a tumor suppressor in liver cancer

Kapil, S., Sharma, B. K., Patil, M., Elattar, S., Yuan, J., Hou, S. X., Kolhe, R. B. & Ande, S., Jan 1 2017, In : Oncotarget. 8, 16, p. 26515-26531 17 p.

Research output: Contribution to journalArticle

9 Scopus citations

The characterization of cell line CRL-2335 as a basal-like breast carcinoma model

Hill Neves, L. A., Ingram, L. & Davis, M. B., 2011, In : Breast Cancer: Basic and Clinical Research. 5, 1, p. 67-72 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis

Eisa, N. H., Jilani, Y., Kainth, K., Redd, P., Lu, S., Bougrine, O., Sater, H. A., Patwardhan, C. A., Shull, A., Shi, H., Liu, K., Elsherbiny, N. M., Eissa, L. A., El-Shishtawy, M. M., Horuzsko, A., Bollag, R., Maihle, N., Roig, J., Korkaya, H., Cowell, J. K. & 1 others, Chadli, A., Apr 5 2019, In : Journal of Biological Chemistry. 294, 14, p. 5246-5260 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation

Zhao, J., Li, X., Guo, M., Yu, J. & Yan, C., May 4 2016, In : BMC Genomics. 17, 1, 335.

Research output: Contribution to journalArticle

24 Scopus citations
140 Scopus citations

The CPLANE protein Intu protects kidneys from ischemia-reperfusion injury by targeting STAT1 for degradation

Wang, S., Liu, A., Wu, G., Ding, H. F., Huang, S., Nahman, S. & Dong, Z., Dec 1 2018, In : Nature communications. 9, 1, 1234.

Research output: Contribution to journalArticle

5 Scopus citations

The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: A regulator of endothelial precursor cells derived from human umbilical cord blood

Guo, A. M., Janic, B., Sheng, J., Falck, J. R., Roman, R. J., Edwards, P. A., Arbab, A. S. & Scicli, A. G., Aug 2011, In : Journal of Pharmacology and Experimental Therapeutics. 338, 2, p. 421-429 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

The effect of the length and flexibility of the side chain of basic amino acids on the binding of antimicrobial peptides to zwitterionic and anionic membrane model systems

Russell, A. L., Williams, B. C., Spuches, A., Klapper, D., Srouji, A. H. & Hicks, R. P., Mar 1 2012, In : Bioorganic and Medicinal Chemistry. 20, 5, p. 1723-1739 17 p.

Research output: Contribution to journalArticle

14 Scopus citations