Biochemistry and Molecular Biology

Research Output 1968 2019

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1994
123 Citations (Scopus)

Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancer

Sehgal, I., Powers, S., Huntley, B., Powis, G., Pittelkow, M. & Maihle, N. J., May 24 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 11, p. 4673-4677 5 p.

Research output: Contribution to journalArticle

Neurotensin
Androgens
Prostatic Neoplasms
Growth
Neurotensin Receptors
61 Citations (Scopus)
Molecular modeling
Micelles
Bradykinin
Dimethyl Sulfoxide
Neuropeptides
66 Citations (Scopus)

Nmr and molecular modeling investigations of the neuropeptide substance P in the presence of 15 mM sodium dodecyl sulfate micelles

Young, J. K., Hicks, R. P. & Hicks, R. P., Jan 1 1994, In : Biopolymers. 34, 11, p. 1449-1462 14 p.

Research output: Contribution to journalArticle

Molecular modeling
Sodium dodecyl sulfate
Micelles
Substance P
Neuropeptides
54 Citations (Scopus)

PA28, an activator of the 20 S proteasome, is composed of two nonidentical but homologous subunits

Mott, J. D., Pramanik, B. C., Moomaw, C. R., Afendis, S. J., DeMartino, G. N. & Slaughter, C. A., Dec 16 1994, In : Journal of Biological Chemistry. 269, 50, p. 31466-31471 6 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Protein Sequence Analysis
Oligomers
Amino Acids
Molecules
104 Citations (Scopus)

Prognostic value of c‐erbB2 overexpression in axillary lymph node positive breast cancer. Results from a randomized adjuvant treatment protocol

Hartmann, L. C., Ingle, J. N., Wold, L. E., Farr, G. H., Grill, J. P., Su, J. Q., Maihle, N. J., Krook, J. E., Witzig, T. E. & Roche, P. C., Jan 1 1994, In : Cancer. 74, 11, p. 2956-2963 8 p.

Research output: Contribution to journalArticle

Clinical Protocols
Lymph Nodes
Staining and Labeling
Breast Neoplasms
Multivariate Analysis
2 Citations (Scopus)

Radioimmunoscintigraphy of CEA/CA 19-9 producing tumors with I-131 labeled monoclonal antibodies

Arbab, A. S., Koizumi, K., Uchiyama, G., Arai, T., Eguchi, H., Matsumoto, Y. & Suda, K., Mar 1 1994, In : Annals of Nuclear Medicine. 8, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

Radioimmunodetection
Monoclonal Antibodies
Sigmoid Neoplasms
Ascending Colon
Neoplasms
50 Citations (Scopus)
Integrin alpha5beta1
Laminin
Fibronectins
Colonic Neoplasms
Growth
22 Citations (Scopus)

Relationship between thyroid hormone transport and neutral amino acid transport in jar human choriocarcinoma cells

Prasad, P. D., Leibach, F. H., Mahesh, V. B. & Ganapathy, V., Jan 1 1994, In : Endocrinology. 134, 2, p. 574-581 8 p.

Research output: Contribution to journalArticle

Neutral Amino Acids
Choriocarcinoma
Thyroid Hormones
Amino Acid Transport System L
Leucine
54 Citations (Scopus)

Selective expression of the high-affinity isoform of the folate receptor (FR-α) in the human placental syncytiotrophoblast and choriocarcinoma cells

Prasad, P. D., Ramamoorthy, S., Moe, A. J., Smith, C. H., Leibach, F. H. & Ganapathy, V., Aug 11 1994, In : BBA - Molecular Cell Research. 1223, 1, p. 71-75 5 p.

Research output: Contribution to journalArticle

Choriocarcinoma
Trophoblasts
Folic Acid
Protein Isoforms
Placenta
5 Citations (Scopus)

Signal transduction during cannibalistic sexual phagocytosis: Calcium is not the trigger but GTP-binding protein function is essential

Lewis, K. E., Browning, D. D. & O'Day, D. H., Jan 1 1994, In : Cellular Signalling. 6, 2, p. 209-215 7 p.

Research output: Contribution to journalArticle

Phagocytosis
GTP-Binding Proteins
Signal Transduction
Calcimycin
Phagocytes
17 Citations (Scopus)

Solid-phase synthesis of biologically active lipopeptides as analogs for spirochetal lipoproteins

DeOgny, L., Pramanik, B. C., Arndt, L. L., Jones, J. D., Rush, J., Slaughter, C. A., Radolf, J. D. & Norgard, M. V., Mar 1 1994, In : Peptide research. 7, 2, p. 91-97 7 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Borrelia burgdorferi Group
Lipopeptides
Treponema pallidum
Spirochaetales
12 Citations (Scopus)

Species difference in the modulatory effect of κ agonist on 5-HT release from ground squirrel and rat hippocampus

Cui, Y., Lee, T. F. & Wang, L. C. H., Jul 4 1994, In : Neuroscience Letters. 175, 1-2, p. 126-128 3 p.

Research output: Contribution to journalArticle

Serotonin Receptor Agonists
Sciuridae
Hippocampus
Serotonin
Naloxone
77 Citations (Scopus)

The interaction of epidermal growth factor and radiation in human head and neck squamous cell carcinoma cell lines with vastly different radiosensitivities

Bonner, J. A., Maihle, N. J., Folven, B. R., Christianson, T. J. H. & spain, K., May 15 1994, In : International Journal of Radiation Oncology, Biology, Physics. 29, 2, p. 243-247 5 p.

Research output: Contribution to journalArticle

Radiation Tolerance
radiation tolerance
cultured cells
Epidermal Growth Factor
cancer
1993
28 Citations (Scopus)

Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinases

Bell, S. M., Connolly, D. C., Maihle, N. J. & Degen, J. L., Jan 1 1993, In : Molecular and Cellular Biology. 13, 9, p. 5888-5897 10 p.

Research output: Contribution to journalArticle

Plasminogen Activators
Oncogene Proteins
Urokinase-Type Plasminogen Activator
Protein-Tyrosine Kinases
Gene Expression
223 Citations (Scopus)

Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals

Robinson, P. J., Sontag, J. M., Liu, J. P., Fykse, E. M., Slaughter, C., McMahontt, H. & Südhof, T. C., Jan 1 1993, In : Nature. 365, 6442, p. 163-166 4 p.

Research output: Contribution to journalArticle

Dynamins
GTP Phosphohydrolases
Protein Kinase C
Phosphorylation
Endocytosis
100 Citations (Scopus)

Expression of a Cocaine-Sensitive Norepinephrine Transporter in the Human Placental Syncytiotrophoblast

Ramamoorthy, S., Prasad, P. D., Kulanthaivel, P., Leibach, F. H., Blakely, R. D. & Ganapathy, V., Jan 1 1993, In : Biochemistry. 32, 5, p. 1346-1353 8 p.

Research output: Contribution to journalArticle

Norepinephrine Plasma Membrane Transport Proteins
Trophoblasts
Cocaine
Norepinephrine
Northern Blotting
72 Citations (Scopus)

Hydroubiquinone-Cytochrome c2 Oxidoreductase from Rhodobacter capsulatus: Definition of a Minimal, Functional Isolated Preparation

Robertson, D. E., Ding, H., Chelminski, P. R., Slaughter, C. A., Hsu, J., Moomaw, C., Tokito, M., Daldal, F. & Dutton, P. L., Jan 1 1993, In : Biochemistry. 32, 5, p. 1310-1317 8 p.

Research output: Contribution to journalArticle

Cytochromes c2
Rhodobacter capsulatus
Heme
Paramagnetic resonance
Oxidoreductases
5 Citations (Scopus)

Induction of murine hepatic glutathione S-transferase by dietary dehydroepiandrosterone

Milewich, L., Marrero, M., Tezabwala, B. U., Bennett, M., Frenkel, R. A. & Slaughter, C. A., Sep 1993, In : Journal of Steroid Biochemistry and Molecular Biology. 46, 3, p. 321-329 9 p.

Research output: Contribution to journalArticle

Dehydroepiandrosterone
Glutathione Transferase
Nutrition
Liver
Diet
61 Citations (Scopus)

PA28, an activator of the 20 S proteasome, is inactivated by proteolytic modification at its carboxyl terminus

Chu-Ping, M., Willy, P. J., Slaughter, C. A. & DeMartino, G. N., Jan 1 1993, In : Journal of Biological Chemistry. 268, 30, p. 22514-22519 6 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Carboxypeptidase B
Carboxypeptidases
Proteins
Molecular Weight
62 Citations (Scopus)

Ribonuclease III cleavage of a bacteriophage T7 processing signal. Divalent cation specificity, and specific anion effects

Li, H., Chelladurai, B. S., Zhang, K. & Nicholson, A. W., Apr 25 1993, In : Nucleic Acids Research. 21, 8, p. 1919-1925 7 p.

Research output: Contribution to journalArticle

Ribonuclease III
Bacteriophage T7
Divalent Cations
Anions
Salts
41 Citations (Scopus)

Sodium- and Chloride-Dependent, Cocaine-Sensitive, High-Affinity Binding of Nisoxetine to the Human Placental Norepinephrine Transporter

Jayanthi, L. D., Prasad, P. D., Ramamoorthy, S., Mahesh, V. B., Leibach, F. H. & Ganapathy, V., Jan 1 1993, In : Biochemistry. 32, 45, p. 12178-12185 8 p.

Research output: Contribution to journalArticle

nisoxetine
Norepinephrine Plasma Membrane Transport Proteins
Cocaine
Sodium Chloride
Norepinephrine
1992
65 Citations (Scopus)

An alternatively processed mRNA from the avian c-erbB gene encodes a soluble, truncated form of the receptor that can block ligand-dependent transformation

Flickinger, T. W., Maihle, N. J. & Kung, H. J., Jan 1 1992, In : Molecular and Cellular Biology. 12, 2, p. 883-893 11 p.

Research output: Contribution to journalArticle

erbB Genes
Ligands
Messenger RNA
Chickens
Transforming Growth Factor alpha
92 Citations (Scopus)

An efficient screen for peroxisome-deficient mutants of Pichia pastoris

Liu, H., Tan, X., Veenhuis, M., McCollum, D. & Cregg, J. M., Jan 1 1992, In : Journal of Bacteriology. 174, 15, p. 4943-4951 9 p.

Research output: Contribution to journalArticle

Peroxisomes
Pichia
Methanol
Oleic Acid
alcohol oxidase
1 Citation (Scopus)

Assessment of renal acidification capacity of stone formers by acid challenge test

Ahmed, A., Pendse, AK., Rajpurohit, S. K. & Singh, PP., 1992, In : Indian Journal of Clinical Biochemistry. 7, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Autophosphorylation of Skeletal Muscle Myosin Light Chain Kinase

Gao, Z. H., Stull, J. T., Moomaw, C. R., Hsu, J. & Slaughter, C. A., Feb 1 1992, In : Biochemistry. 31, 26, p. 6126-6133 8 p.

Research output: Contribution to journalArticle

Skeletal Muscle Myosins
Myosin-Light-Chain Kinase
Calmodulin
Phosphorylation
Catalytic Domain
1 Citation (Scopus)

Complete distal renal tubular acidosis: Biochemical profile of a case

Rajpurohit, S. K., Pendse, AK., Ahmed, A. & Singh, PP., 1992, In : Indian Journal of Clinical Biochemistry. 7, 2, p. 205-206 2 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Conformational analysis of met‐enkephalin in both aqueous solution and in the presence of sodium dodecyl sulfate micelles using multidimensional NMR and molecular modeling

Graham, W. H., Carter, E. S. & Hicks, R. P., Jan 1 1992, In : Biopolymers. 32, 12, p. 1755-1764 10 p.

Research output: Contribution to journalArticle

Molecular modeling
Sodium dodecyl sulfate
Micelles
Sodium Dodecyl Sulfate
Conformations
21 Citations (Scopus)

Cytomegalovirus genomes demonstrates by polymerase chain reaction in synovial fluid from rheumatoid arthritis patients

Murayama, T., Jisaki, F., Ayata, M., Sakamuro, D., Hironaka, T., Hirai, K., Tsuchiya, N., Ito, K. & Furukawa, T., Jan 1 1992, In : Clinical and Experimental Rheumatology. 10, 2, p. 161-164 4 p.

Research output: Contribution to journalArticle

Synovial Fluid
Cytomegalovirus
Rheumatoid Arthritis
Genome
Polymerase Chain Reaction
31 Citations (Scopus)

Identification and Localization of a Cysteinyl Residue Critical for the Trypsin-like Catalytic Activity of the Proteasome

Dick, L. R., Moomaw, C. R., Pramanik, B. C., DeMartino, G. N. & Slaughter, C. A., Feb 1 1992, In : Biochemistry. 31, 32, p. 7347-7355 9 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Trypsin
Catalyst activity
Peptide Hydrolases
Amino Acids
246 Citations (Scopus)

Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor

Lust, J. A., Donovan, K. A., Kline, M. P., Greipp, P. R., Kyle, R. A. & Maihle, N. J., Jan 1 1992, In : Cytokine. 4, 2, p. 96-100 5 p.

Research output: Contribution to journalArticle

Interleukin-6 Receptors
Messenger RNA
Sequence Analysis
B-Lymphocytes
Interleukin-7 Receptors
47 Citations (Scopus)

Proliferation of human colon cancer cells: Role of epidermal growth factor and transforming growth factorα

Huang, S., Trujillo, J. M. & Chakrabarty, S., Dec 2 1992, In : International Journal of Cancer. 52, 6, p. 978-986 9 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Epidermal Growth Factor
Colonic Neoplasms
Cell Line
Intercellular Signaling Peptides and Proteins
219 Citations (Scopus)

Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product

Seabra, M. C., Brown, M. S., Slaughter, C. A., Südhof, T. C. & Goldstein, J. L., Sep 18 1992, In : Cell. 70, 6, p. 1049-1057 9 p.

Research output: Contribution to journalArticle

Choroideremia
rab3A GTP-Binding Protein
Purification
Conserved Sequence
Genes
40 Citations (Scopus)

Signals from focal adhesions

Burridge, K., Petch, L. A. & Romer, L. H., Oct 1992, In : Current Biology. 2, 10, p. 537-539 3 p.

Research output: Contribution to journalArticle

Focal Adhesions
adhesion
25 Citations (Scopus)

Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles: Transport and binding

Prasad, P. D., Leibach, F. H., Mahesh, V. B. & Ganapathy, V., Nov 25 1992, In : Journal of Biological Chemistry. 267, 33, p. 23632-23639 8 p.

Research output: Contribution to journalArticle

Antiporters
Transport Vesicles
Brushes
Microvilli
Cations
63 Citations (Scopus)

The hbpA gene of Haemophilus influenzae type b encodes a heme-binding lipoprotein conserved among heme-dependent Haemophilus species

Hanson, M. S., Slaughter, C. A. & Hansen, E. J., Jan 1 1992, In : Infection and Immunity. 60, 6, p. 2257-2266 10 p.

Research output: Contribution to journalArticle

Haemophilus
Haemophilus influenzae type b
Staphylococcal Protein A
Heme
Lipoproteins
39 Citations (Scopus)

The interactions of neuropeptides with membrane model systems: A case study

Hicks, R. P., Beard, D. J. & Young, J. K., Jan 1 1992, In : Biopolymers. 32, 1, p. 85-96 12 p.

Research output: Contribution to journalArticle

Bradykinin
Substance P
Neuropeptides
Membranes
Lysophosphatidylcholines
7 Citations (Scopus)

The involvement of Ca2+ and myosin light chain kinase in collagen-induced platelet activation

Lokeshwar, V. B. & Bourguignon, L. Y. W., Jan 1 1992, In : Cell Biology International Reports. 16, 9, p. 883-897 15 p.

Research output: Contribution to journalArticle

Myosin-Light-Chain Kinase
Myosin Light Chains
Platelet Activation
Collagen
Phosphorylation
16 Citations (Scopus)

The use of UV‐visible spectroscopy for the determination of hydrophobic interactions between neuropeptides and membrane model systems

Young, J. K., Graham, W. H., Beard, D. J. & Hicks, R. P., Jan 1 1992, In : Biopolymers. 32, 8, p. 1061-1064 4 p.

Research output: Contribution to journalArticle

Lysophosphatidylcholines
Rabies
Sodium dodecyl sulfate
Micelles
Bradykinin
130 Citations (Scopus)

Transcription of the hypersensitive site HS2 enhancer in erythroid cells

Tuan Lo, D., Kong, S. & Hu, K., Dec 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 23, p. 11219-11223 5 p.

Research output: Contribution to journalArticle

Erythroid Cells
Chloramphenicol O-Acetyltransferase
Genes
RNA
Globins
58 Citations (Scopus)

Tyrosine phosphatase activity of lymphoma CD45 (GP180) is regulated by a direct interaction with the cytoskeleton

Lokeshwar, V. B. & Bourguignon, L. Y. W., Jan 1 1992, In : Journal of Biological Chemistry. 267, 30, p. 21551-21557 7 p.

Research output: Contribution to journalArticle

Cytoskeleton
Phosphoric Monoester Hydrolases
Spectrin
Tyrosine
Lymphoma
63 Citations (Scopus)

Unification of the ferritin family of proteins

Grossman, M. J., Hinton, S. M., Minak-Bernero, V., Slaughter, C. A. & Stiefel, E. I., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 6, p. 2419-2423 5 p.

Research output: Contribution to journalArticle

Ferritins
Azotobacter vinelandii
Proteins
Environmental Monitoring
Heme
1991
46 Citations (Scopus)

1,3,8-Trisubstituted Xanthines. Effects of Substitution Pattern upon Adenosine Receptor A1/A2 Affinity

Erickson, R. H., Hiner, R. N., Feeney, S. W., Blake, P. R., Rzeszotarski, W. J., Hicks, R. P., Costello, D. G. & Abreu, M. E., Apr 1 1991, In : Journal of Medicinal Chemistry. 34, 4, p. 1431-1435 5 p.

Research output: Contribution to journalArticle

Xanthines
Adenosine A2 Receptors
Adenosine A1 Receptors
varespladib methyl
44 Citations (Scopus)

A conserved sequence element in ribonuclease III processing signals is not required for accurate in vitro enzymatic cleavage

Chelladurai, B. S., Li, H. & Nicholson, A. W., Apr 25 1991, In : Nucleic Acids Research. 19, 8, p. 1759-1766 8 p.

Research output: Contribution to journalArticle

Ribonuclease III
Conserved Sequence
RNA
Base Pairing
RNA Phages
63 Citations (Scopus)

Acylation of the lymphoma transmembrane glycoprotein, GP85, may be required for GP85-ankyrin interaction

Bourguignon, L. Y. W., Kalomiris, E. L. & Lokeshwar, V. B., Nov 5 1991, In : Journal of Biological Chemistry. 266, 18, p. 11761-11765 5 p.

Research output: Contribution to journalArticle

Ankyrins
Acylation
Palmitic Acid
Lymphoma
Glycoproteins
10 Citations (Scopus)
Acquired Immunodeficiency Syndrome
HIV
Peptides
Serum
Proteins
58 Citations (Scopus)

Changes observed in antioxidant system in the blood of post-menopausal women with breast cancer

Kumar, K., Thangaraju, M. & Sachdanandam, P., Dec 1 1991, In : Biochemistry International. 25, 2, p. 371-380 10 p.

Research output: Contribution to journalArticle

Blood
Antioxidants
Breast Neoplasms
Lipid Peroxidation
Ceruloplasmin
48 Citations (Scopus)

Cloning of murine tissue factor and regulation of gene expression by transforming growth factor type β1

Ranganathan, G., Blatti, S. P., Subramaniam, M., Fass, D. N., Maihle, N. J. & Getz, M. J., Jan 31 1991, In : Journal of Biological Chemistry. 266, 1, p. 496-501 6 p.

Research output: Contribution to journalArticle

Cloning
Gene Expression Regulation
Thromboplastin
Transforming Growth Factors
Gene expression
81 Citations (Scopus)

Degradation of Oxidized Insulin B Chain by the Multiproteinase Complex Macropain (Proteasome)

Dick, L. R., Moomaw, C. R., DeMartino, G. N. & Slaughter, C. A., Mar 1 1991, In : Biochemistry. 30, 10, p. 2725-2734 10 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Insulin
Degradation
Peptides
Antipain
20 Citations (Scopus)

Growth modulation by epidermal growth factor (EGF) in human colonic carcinoma cells: Constitutive expression of the human EGF gene

Huang, S., Lin, PF. F., Fan, D., Price, J. E., Trujillo, J. M. & Chakrabarty, S., Aug 1991, In : Journal of Cellular Physiology. 148, 2, p. 220-227 8 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Genes
Cells
Modulation
Carcinoma
102 Citations (Scopus)

Molecular genetics of kinesin light chains: Generation of isoforms by alternative splicing

Cyr, J. L., Pfister, K. K., Bloom, G. S., Slaughter, C. A. & Brady, S. T., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 22, p. 10114-10118 5 p.

Research output: Contribution to journalArticle

Kinesin
Alternative Splicing
Molecular Biology
Protein Isoforms
Light