Biochemistry and Molecular Biology

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2001

An incremental increase in the complexity of peptides bound to class II MHC changes the diversity of positively selected αβ TCRs

Pacholczyk, R. W., Kraj, P. & Ignatowicz, L., Feb 15 2001, In : Journal of Immunology. 166, 4, p. 2357-2363 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine

Moore, P., El-sherbeny, A., Roon, P., Schoenlein, P. V., Ganapathy, V. & Smith, S. B., Jan 1 2001, In : Experimental eye research. 73, 1, p. 45-57 13 p.

Research output: Contribution to journalArticle

120 Scopus citations

A preliminary study of serum concentrations of soluble epidermal growth factor receptor (sErbB1), gonadotropins, and steroid hormones in healthy men and women

Baron, A. T., Lafky, J. M., Maihle, N. J., Suman, V. J., Hillman, D. W., Buenafe, M. C., Boardman, C. H., Podratz, K. C. & Perez, E. A., Jan 1 2001, In : Cancer Epidemiology Biomarkers and Prevention. 10, 11, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Associations between climate variables and asthma visits to accident and emergency facilities in Trinidad, West Indies

Ivey, M. A., Simeon, D. T., Juman, S., Hassanally, R., Williams, K. & Monteil, M. A., Jan 1 2001, In : Allergology International. 50, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Augmentation in expression of activation-induced genes differentiates memory from naive CD4+ T cells and is a molecular mechanism for enhanced cellular response of memory CD4+ T cells

Liu, K., Li, Y., Prabhu, V., Young, L., Becker, K. G., Munson, P. J. & Weng, N. P., Jun 15 2001, In : Journal of Immunology. 166, 12, p. 7335-7344 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Chemoattractant-stimulated NF-κB Activation Is Dependent on the Low Molecular Weight GTPase RhoA

Huang, S., Chen, L. Y., Zuraw, B. L., Ye, R. D. & Pan, Z. K., Nov 2 2001, In : Journal of Biological Chemistry. 276, 44, p. 40977-40981 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Cloning and functional characterization of a new subtype of the amino acid transport system N

Nakanishi, T., Kekuda, R., Fei, Y. J., Hatanaka, T., Sugawara, M., Martindale, R. G., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jan 1 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1757-C1768

Research output: Contribution to journalArticle

85 Scopus citations

Effects of the incorporation of CHAPS into SDS micelles on neuropeptide-micelle binding: Separation of the role of electrostatic interactions from hydrophobic interactions

Whitehead, T. L., Jones, L. M. & Hicks, R. P., Jun 11 2001, In : Biopolymers. 58, 7, p. 593-605 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Evaluation of crossed cerebellar diaschisis in 30 patients with major cerebral artery occlusion by means of quantitative I-123 IMP SPECT

Miyazawa, N., Toyama, K., Arbab, A. S., Koizumi, K., Arai, T. & Nukui, H., Jan 1 2001, In : Annals of Nuclear Medicine. 15, 6, p. 513-519 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A

Hatanaka, T., Huang, W., Ling, R., Prasad, P. D., Sugawara, M., Leibach, F. H. & Ganapathy, V., Feb 9 2001, In : Biochimica et Biophysica Acta - Biomembranes. 1510, 1-2, p. 10-17 8 p.

Research output: Contribution to journalArticle

83 Scopus citations

Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina

Shamsul Ola, M., Martin, P. M., El-Sherbeny, A., Roon, P., Agarwal, N., Sarthy, V. P., Casellas, P., Ganapathy, V. & Smith, S. B., Nov 1 2001, In : Molecular Brain Research. 95, 1-2, p. 86-95 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Feeding daidzein to late pregnant sows influences the estrogen receptor beta and type 1 insulin-like growth factor receptor mRNA expression in newborn piglets

Ren, M. Q., Kuhn, G., Wegner, J., Nürnberg, G., Chen, J. & Ender, K., Aug 6 2001, In : Journal of Endocrinology. 170, 1, p. 129-135 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Functional Analysis of Type 1α cGMP-dependent Protein Kinase Using Green Fluorescent Fusion Proteins

Browning, D. D., Mc Shane, M., Marty, C. & Ye, R. D., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 13039-13048 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A

Ling, R., Bridges, C. C., Sugawara, M., Fujita, T., Leibach, F. H., Prasad, P. D. & Ganapathy, V., May 2 2001, In : Biochimica et Biophysica Acta - Biomembranes. 1512, 1, p. 15-21 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Na+ - and CI- -coupled active transport of carnitine by the amino acid transporter ATB0,+ from mouse colon expressed in HRPE cells and Xenopus oocytes

Nakanishi, T., Hatanaka, T., Huang, W., Prasad, P. D., Leibach, F. H., Ganapathy, M. E. & Ganapathy, V., Apr 15 2001, In : Journal of Physiology. 532, 2, p. 297-304 8 p.

Research output: Contribution to journalArticle

149 Scopus citations

Na+- and Cl--coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B0,+

Hatanaka, T., Nakanishi, T., Huang, W., Leibach, F. H., Prasad, P. D., Ganapathy, V. & Ganapathy, M. E., Jan 1 2001, In : Journal of Clinical Investigation. 107, 8, p. 1035-1043 9 p.

Research output: Contribution to journalArticle

55 Scopus citations

Positive selection of CD4+ t cells is induced in vivo by agonist and inhibited by antagonist peptides

Kraj, P., Pacholczyk, R., Ignatowicz, H., Kisielow, P., Jensen, P. & Ignatowicz, L., Aug 20 2001, In : Journal of Experimental Medicine. 194, 4, p. 407-416 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Recent advances in NMR: Expanding its role in rational drug design

Hicks, R. P., Jan 1 2001, In : Current Medicinal Chemistry. 8, 6, p. 627-650 24 p.

Research output: Contribution to journalArticle

28 Scopus citations

Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells

Bridges, C. C., Ola, M. S., Prasad, P. D., El-Sherbeny, A., Ganapathy, V. & Smith, S. B., Jan 1 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1825-C1836

Research output: Contribution to journalArticle

45 Scopus citations

Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells

Bridges, C. C., Kekuda, R., Wang, H., Prasad, P. D., Mehta, P., Huang, W., Smith, S. B. & Ganapathy, V., Jan 30 2001, In : Investigative Ophthalmology and Visual Science. 42, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

101 Scopus citations

Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N

Nakanishi, T., Sugawara, M., Huang, W., Martindale, R. G., Leibach, F. H., Ganapathy, M. E., Prasad, P. D. & Ganapathy, V., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 281, 5, p. 1343-1348 6 p.

Research output: Contribution to journalArticle

84 Scopus citations

Targeting the sodium-dependent multivitamin transporter (SMVT) for improving the oral absorption properties of a retro-inverso Tat nonapeptide

Ramanathan, S., Pooyan, S., Stein, S., Prasad, P. D., Wang, J., Leibowitz, M. J., Ganapathy, V. & Sinko, P. J., Sep 11 2001, In : Pharmaceutical Research. 18, 7, p. 950-956 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4)

Friedrich, A., George, R. L., Bridges, C. C., Prasad, P. D. & Ganapathy, V., Jun 6 2001, In : Biochimica et Biophysica Acta - Biomembranes. 1512, 2, p. 299-307 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Vitamin C transport in human lens epithelial cells: Evidence for the presence of SVCT2

Kannan, R., Stolz, A., Ji, Q., Prasad, P. D. & Ganapathy, V., Jan 1 2001, In : Experimental eye research. 73, 2, p. 159-165 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

α/βTCRs differ in the degree of their specificity for the positively selecting MHC/peptide ligand

Kraj, P., Pacholczyk, R. & Ignatowicz, L., Feb 15 2001, In : Journal of Immunology. 166, 4, p. 2251-2259 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

αv Integrin, p38 Mitogen-activated Protein Kinase, and Urokinase Plasminogen Activator Are Functionally Linked in Invasive Breast Cancer Cells

Chen, J., Baskerville, C., Han, Q., Pan, Z. K. & Huang, S., Dec 21 2001, In : Journal of Biological Chemistry. 276, 51, p. 47901-47905 5 p.

Research output: Contribution to journalArticle

51 Scopus citations
2002

A chromosomal region 7p11.2 transcript map: Its development and application to the study of EGFR amplicons in glioblastoma

Eley, G. D., Reiter, J. L., Pandita, A., Park, S., Jenkins, R. B., Maihle, N. J. & James, C. D., Jan 1 2002, In : Neuro-Oncology. 4, 2, p. 86-94 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
74 Scopus citations

Amphiphilic gels with controlled mesh dimensions for insulin delivery

Kennedy, J. P., Fenyvesi, G., Na, S., Keszler, B. & Rosenthal, K. S., Dec 1 2002, In : ACS Symposium Series. 833, 1, p. 710-711 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Analysis of genome by visualization of genomic signature

Choi, J-H., Lee, S. K., Yee, S. B., Kim, Y. J., Cho, H. G. & Kim, K. W., Mar 1 2002, In : Korean Journal of Genetics. 24, 1, p. 97-104 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Analysis of sigma receptor (σR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice

Shamsul Ola, M., Martin, P. M., Maddox, D., El-Sherbeny, A., Huang, W., Roon, P., Agarwal, N., Ganapathy, V. & Smith, S. B., Nov 15 2002, In : Molecular Brain Research. 107, 2, p. 97-107 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

A randomized phase II study of sequential docetaxel and doxorubicin/cyclophosphamide in patients with metastatic breast cancer

Kugler, J. W., Perez, E. A., Geeraerts, L., Lafky, J. M., Ingle, J. N., Suman, V. J., Adjei, A. A., Baron, A. T., Hatfield, A. K., Maihle, N., Michalak, J. C. & Kuross, S. A., Aug 1 2002, In : Annals of Oncology. 13, 8, p. 1225-1235 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Capillary electrophoresis determination of biflavanones from Garcinia kola in three traditional African medicinal formulations

Okunji, C. O., Ware, T. A., Hicks, R. P., Iwu, M. M. & Skanchy, D. J., Jun 19 2002, In : Planta Medica. 68, 5, p. 440-444 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Characterization of the main phase transition in 1,2-dipalmitoyl-phosphatidylcholine LUVs by 1H NMR

Kennedy, A., Hmel, P. J., Seelbaugh, J., Quiles, J. G., Hicks, R. & Reid, T. J., Dec 12 2002, In : Journal of Liposome Research. 12, 3, p. 221-237 17 p.

Research output: Contribution to journalArticle

13 Scopus citations

Comparing mRNA levels of genes encoding leptin, leptin receptor, and lipoprotein lipase between dairy and beef cattle

Ren, M. Q., Wegner, J., Bellmann, O., Brockmann, G. A., Schneider, F., Teuscher, F. & Ender, K., Oct 1 2002, In : Domestic Animal Endocrinology. 23, 3, p. 371-381 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity

Manfredini, S., Pavan, B., Vertuani, S., Scaglianti, M., Compagnone, D., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Prasad, P. D. & Dalpiaz, A., Jan 31 2002, In : Journal of Medicinal Chemistry. 45, 3, p. 559-562 4 p.

Research output: Contribution to journalArticle

85 Scopus citations

Dissociated ROS production and ceramide generation in sulfasalazine-induced cell death in Raw 264.7 cells

Salh, B., Assi, K., Huang, S., O'Brien, L., Steinbrecher, U. & Gómez-Muñoz, A., Oct 1 2002, In : Journal of Leukocyte Biology. 72, 4, p. 790-799 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells

Bachmann, A., Hanke, B., Zawatzky, R., Soto, U., Van Riggelen, J., Zur Hausen, H. & Rösl, F., Jan 1 2002, In : Journal of Virology. 76, 1, p. 280-291 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice

Naggar, H., Shamsul Ola, M., Martin, P. M., Huang, W., Bridges, C. C., Ganapathy, V. & Smith, S. B., Feb 11 2002, In : Investigative Ophthalmology and Visual Science. 43, 2, p. 556-563 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Effect of moderate caloric restriction and/or weight cycling on mammary tumor incidence and latency in MMTV-Neu female mice

Pape-Ansorge, K. A., Grande, J. P., Christensen, T. A., Maihle, N. J. & Cleary, M. P., Jan 1 2002, In : Nutrition and Cancer. 44, 2, p. 162-168 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

EGF receptor/ErbB isoforms as serum biomarkers in breast and ovarian cancer

Maihle, N. J., Lafky, J. M., Baron, A. T., Boardman, C. H., Greenwood, T. M., Christensen, T. A., Reiter, J. L., Cora, E. M., Lee, H., Suman, V. J., Fishman, D. A., Perez, E. A. & Podratz, K. C., Mar 1 2002, In : Journal of Clinical Ligand Assay. 25, 1, p. 57-60 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Endogenous reactivation of the RARβ2 tumor suppressor gene epigenetically silenced in breast cancer

Sirchia, S. M., Ren, M., Pili, R., Sironi, E., Somenzi, G., Ghidoni, R., Toma, S., Nicolò, G. & Sacchi, N., May 1 2002, In : Cancer Research. 62, 9, p. 2455-2461 7 p.

Research output: Contribution to journalArticle

145 Scopus citations

Generation and characterization of polyclonal antibodies specific for human p110 sEGFR

Christensen, T. A., Reiter, J. L., Baron, A. T. & Maihle, N. J., Jan 1 2002, In : Hybridoma and Hybridomics. 21, 3, p. 183-189 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

Wiemann, S. U., Ande, S., Tsahuridu, M., Tillmann, H. L., Zender, L., Klempnauer, J., Flemming, P., Franco, S., Blasco, M. A., Manns, M. P. & Lenhard Rudolph, K., Jul 22 2002, In : FASEB Journal. 16, 9, p. 935-942 8 p.

Research output: Contribution to journalArticle

337 Scopus citations

IL-1 receptor-associated kinase and low molecular weight GTPase RhoA signal molecules are required for bacterial lipopolysaccharide-induced cytokine gene transcription

Chen, L. Y., Zuraw, B. L., Liu, F. T., Huang, S. & Pan, Z. K., Oct 1 2002, In : Journal of Immunology. 169, 7, p. 3934-3939 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Inhibition of system A amino acid transport activity by ethanol in BeWo choriocarcinoma cells

Jones, C. R., Srinivas, S. R., Devoe, L. D., Ganapathy, V. & Prasad, P. D., Jan 1 2002, In : American journal of obstetrics and gynecology. 187, 1, p. 209-216 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Leptin - A growth factor in normal and malignant breast cells and for normal mammary gland development

Hu, X., Juneja, S. C., Maihle, N. J. & Cleary, M. P., Nov 20 2002, In : Journal of the National Cancer Institute. 94, 22, p. 1704-1711 8 p.

Research output: Contribution to journalArticle

Open Access
368 Scopus citations

Peptide specificity of thymic selection of CD4+CD25+ T cells

Pacholczyk, R., Kraj, P. & Ignatowicz, L., Jan 15 2002, In : Journal of Immunology. 168, 2, p. 613-620 8 p.

Research output: Contribution to journalArticle

83 Scopus citations

Pharmacokinetic and pharmacodynamic investigation of efavirenz in the semen and blood of human immunodeficiency virus type 1-infected men

Reddy, Y. S., Gotzkowsky, S. K., Eron, J. J., Kim, J. Y., Fiske, W. D., Fiscus, S. A., Petch, L., Cohen, M. S. & Kashuba, A. D. M., Nov 1 2002, In : Journal of Infectious Diseases. 186, 9, p. 1339-1343 5 p.

Research output: Contribution to journalArticle

39 Scopus citations
8 Scopus citations