Cardiology

Projects

Projects per year 1992 2017

• 7 Finished
• 68 Not started

Projects per year

Search results

• Not started

  Mitochondrial KATP Channel in Cardioprotection

  Ashraf, M., Ashraf, M. & Ashraf, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • mitochondrial K(ATP) channel 100%
  • Nitric Oxide 17%
  • Up-Regulation 7%
  • RNA Isoforms 7%
  • Pharmacology 7%

• PDE5A Inhibition Stimulates Stem Cell Survival &Differentiation

  Ashraf, M., Ashraf, M., Ashraf, M., Ashraf, M., Ashraf, M. & Ashraf, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Stem Cells 100%
  • Tadalafil 59%
  • Cell Survival 51%
  • Cell Differentiation 44%
  • Heart 44%

• Stem Cells in Cardiac Repair and Angiogenesis

  Ashraf, M., Ashraf, M., Ashraf, M., Ashraf, M., Ashraf, M. & Ashraf, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Bone Marrow Cells 100%
  • Stem Cells 93%
  • Myocardium 79%
  • Muscle Cells 58%
  • Phenotype 25%

• PURCHASE OF A TRANSMISSION ELECTRON MICROSCOPE

  Ashraf, M. & Ashraf, M.

  National Institutes of Health

  Project: Research project

  • transmission electron microscopes 100%
  • microscopes 19%
  • human resources 19%
  • medical facilities 16%
  • electron microscopy 16%

• MYOCARDIAL ISCHEMIC INJURY: MODIFICATION BY DRUG THERAPY

  Ashraf, M., Ashraf, M. & Ashraf, M.

  National Heart, Lung, and Blood Institute, National Institutes of Health

  Project: Research project

  • Hydroxyl Radical 100%
  • Muscle Cells 62%
  • Wounds and Injuries 60%
  • Reperfusion 29%
  • Reactive Oxygen Species 27%

• Integration Free IPS Cells-Derived Progenitors for Cardiac Regeneration

  Ashraf, M., Ashraf, M., Rehman, J. & Ashraf, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Induced Pluripotent Stem Cells 100%
  • Skeletal Myoblasts 78%
  • Stem Cells 52%
  • Heart 45%
  • Regeneration 44%

• A novel therapeutic strategy to eradicate breast cancer through Hsp90 inhibition and reduced immune tolerance

  Chadli, A.

  Project: Research project

  • HSP90 Heat-Shock Proteins 100%
  • Neoplasms 43%
  • Immune Tolerance 30%
  • Immunotherapy 22%
  • Immune System 20%

• Epigenetic regulation of HDAC9 in obesity and atherosclerosis

  Weintraub, N. L.

  Project: Research project

  • Histone Deacetylases 100%
  • Obesity 59%
  • Diet 45%
  • Adipose Tissue 33%
  • Atherosclerosis 32%

• SMOOTH MUSCLE CELL PHENOTYPIC CONTROL BY HOMEOPROTEINS

  Miano, J. M.

  Project: Research project

• Regulation and Function of Myocardin in Vascular Pathobiology

  Miano, J. M. & MIANO, J. M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • myocardin 100%
  • Serum Response Factor 30%
  • Vascular Smooth Muscle 27%
  • Smooth Muscle Myocytes 24%
  • Vascular Diseases 17%

• Regulation and Function of SRF in Vascular Pathiobiology

  Miano, J. M. & MIANO, J.

  Project: Research project

  • Serum Response Factor 100%
  • Vascular Smooth Muscle 55%
  • Smooth Muscle Myocytes 49%
  • Vascular Diseases 30%
  • Clustered Regularly Interspaced Short Palindromic Repeats 28%

• Redox Regulation of Cu Importer CTR1 in Angiogenesis

  Fukai, T. & Fukai, M.

  Project: Research project

  • Reactive Oxygen Species 100%
  • Endothelial Cells 92%
  • Oxidation-Reduction 68%
  • Vascular Endothelial Growth Factor A 61%
  • Organized Financing 42%

• Mechanisms of myeloperoxidase and Nox4 interactions in abdominal aortic aneurysm

  Weintraub, N. L.

  Project: Research project

  • Abdominal Aortic Aneurysm 100%
  • Peroxidase 53%
  • prostaglandin D2 receptor 16%
  • Neutrophil Activation 12%
  • Smooth Muscle Myocytes 8%

• HDAC9, Aging and Alzheimer's Disease

  Weintraub, N. L. & LU, X.

  Project: Research project

  • Histone Deacetylases 100%
  • Adipose Tissue 40%
  • Brain 36%
  • Alzheimer Disease 9 21%
  • Adipokines 14%

• Hypoxia and cardiac stem cell homing

  Tang, Y. L., TANG, Y. L., TANG, Y. L., TANG, Y. L., TANG, Y. L. & TANG, Y. L.

  Project: Research project

  • Enhancer of Zeste Homolog 2 Protein 100%
  • Mesenchymal Stem Cells 51%
  • Stem Cells 47%
  • Hypoxia 32%
  • CXCR4 Receptors 22%

• Angiotensin II, oxidative stress and aneurysm formation

  Weintraub, N. L.

  Project: Research project

  • Abdominal Aortic Aneurysm 100%
  • Peroxidase 63%
  • Angiotensin II 55%
  • pancreatic elastase II 30%
  • Oxidative Stress 30%

• SMOOTH MUSCLE CELL PHENOTYPIC CONTROL BY HOMEODOMAIN PRO

  Miano, J. M.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

• Regulation and Function of SRF in Vascular Pathiobiology

  Miano, J. M. & MIANO, J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Serum Response Factor 100%
  • Vascular Smooth Muscle 55%
  • Smooth Muscle Myocytes 49%
  • Vascular Diseases 30%
  • Clustered Regularly Interspaced Short Palindromic Repeats 28%

• Transcriptional Control of Myocardin and the MYOCARDome

  Miano, J. M., MIANO, J. & MIANO, J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Vascular Smooth Muscle 100%
  • Smooth Muscle Myocytes 89%
  • myocardin 80%
  • Clustered Regularly Interspaced Short Palindromic Repeats 35%
  • Cell Differentiation 33%

• Role of Cysteine Sulfenic Acid Formation in Compartmentalization of VEGF Signalin

  Fukai, M., USHIO-FUKAI, M. & USHIO-FUKAI, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Cysteine 100%
  • Reactive Oxygen Species 84%
  • Vascular Endothelial Growth Factor A 68%
  • cysteinesulfenic acid 35%
  • Endothelial Cells 32%

• hiPS cells derived skeletal muscle progenitors and their extracellular vesicles for treatment of sarcopenia

  Xuan, W.

  National Institute on Aging

  Project: Research project

  • Extracellular Vesicles 100%
  • Stem Cells 98%
  • Sarcopenia 75%
  • givinostat 73%
  • Muscles 65%

• Innovative Approaches to Treat Duchenne Muscular Dystrophy Using iPSC-Derived Muscle Progenitors

  Weintraub, N. L., Tang, Y. L., Ashraf, M. & Ashraf, M.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • Duchenne Muscular Dystrophy 100%
  • Induced Pluripotent Stem Cells 96%
  • Muscles 70%
  • Stem Cells 46%
  • Exosomes 25%

• Role of Cysteine Sulfenic Acid Formation in Compartmentalization of VEGF Signalin

  Fukai, M.

  Project: Research project

  • Cysteine 100%
  • Reactive Oxygen Species 84%
  • Vascular Endothelial Growth Factor A 68%
  • cysteinesulfenic acid 35%
  • Endothelial Cells 32%

• Regulation and Function of Myocardin in Vascular Pathobiology

  Miano, J. M.

  Project: Research project

  • myocardin 100%
  • Serum Response Factor 30%
  • Vascular Smooth Muscle 27%
  • Smooth Muscle Myocytes 24%
  • Vascular Diseases 17%

• Endotoxin, Vascular Inflammation and Atherosclerosis

  Weintraub, N. L.

  Project: Research project

  • Endotoxins 100%
  • Atherosclerosis 44%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 35%
  • Blood Vessels 26%
  • Coronary Vessels 22%

• Notch1/miR-322 Axis in Stem Cell Mediated Vascular Repair

  Weintraub, N. L., Tang, Y. L. & Ashraf, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Stem Cells 100%
  • Mesenchymal Stem Cells 81%
  • Blood Vessels 62%
  • Cell Survival 34%
  • human MIRN424 microrna 30%

• Regulation of Vascular Smooth Muscle Cell Phenotype by a Novel Isoform of Glucose-6-Phosphate Dehydrogenase

  Miano, J. M., Gupte, S. & Miano, J. M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Vascular Smooth Muscle 100%
  • Smooth Muscle Myocytes 89%
  • Glucosephosphate Dehydrogenase 71%
  • myocardin 68%
  • Phenotype 39%

• Protein Disulfide Isomerase as Novel Redox Sensor in VEGF Signaling

  Fukai, M.

  Project: Research project

  • Oxidation-Reduction 100%
  • Protein Disulfide-Isomerases 81%
  • Vascular Endothelial Growth Factor A 69%
  • Reactive Oxygen Species 46%
  • Mitochondrial Dynamics 44%

• Angiomyogenesis With Myoblast Derived iPS Cells

  Ashraf, M., Ashraf, M., Wang, Y., Ashraf, M., Ashraf, M., Ashraf, M. & Wang, Y.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • induced pluripotent stem cells 100%
  • myoblasts 97%
  • fibroblasts 25%
  • animal models 25%
  • stem cells 21%

• 02 RADICALS-MEDIATED CARDIAC INJURY DURING CA++ PARADOX

  Ashraf, M., Ashraf, M. & Ashraf, M.

  National Institutes of Health, National Heart, Lung, and Blood Institute

  Project: Research project

  • hydroxide ion 100%
  • Muscle Cells 80%
  • Endothelial Cells 55%
  • Wounds and Injuries 42%
  • Superoxides 25%

• Mechanistic basis of myoblast therapy &angiomyogenesis

  Ashraf, M., Ashraf, M. & Ashraf, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • myoblasts 100%
  • prognosis 17%
  • therapeutics 14%
  • growth factors 13%
  • myocardial infarction 12%

• ADENOSINE AND CA++ IN MYOCARDIAL PRECONDITIONING

  Ashraf, M. & Ashraf, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Adenosine 100%
  • Calcium 59%
  • Catecholamines 40%
  • Wounds and Injuries 35%
  • Heart 28%

• Cu Transporting ATPase and Diabetic Vascular Complications

  Fukai, T. & Fukai, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Vascular Endothelial Growth Factor A 100%
  • Diabetic Angiopathies 88%
  • Copper-Transporting ATPases 53%
  • Endothelial Cells 36%
  • Microvessels 33%

• Novel Interplay of KILN and MKL1 in Vascular Pathophysiology

  Long, X., LONG, X. & LONG, X.

  Project: Research project

  • Vascular Smooth Muscle 100%
  • Smooth Muscle Myocytes 89%
  • Bacterial Artificial Chromosomes 40%
  • Long Noncoding RNA 31%
  • Vascular Diseases 28%

• Copper transport protein and inflammatory angiogenesis

  Fukai, T., Fukai, M. & Fukai, M.

  Project: Research project

  • NADPH Oxidases 100%
  • Reactive Oxygen Species 59%
  • Endothelial Cells 46%
  • Carrier Proteins 42%
  • Copper Transport Proteins 40%

• hiPS cells derived skeletal muscle progenitors and their extracellular vesicles for treatment of sarcopenia

  Xuan, W.

  Project: Research project

  • Extracellular Vesicles 100%
  • Stem Cells 98%
  • Sarcopenia 75%
  • givinostat 73%
  • Muscles 65%

• Cu Transporting ATPase and Diabetic Vascular Complications

  Fukai, T. & Fukai, M.

  Project: Research project

  • Vascular Endothelial Growth Factor A 100%
  • Diabetic Angiopathies 88%
  • Copper-Transporting ATPases 53%
  • Endothelial Cells 36%
  • Microvessels 33%

• Bifunctionality of Myocardin in Myogenesis

  Miano, J. M.

  Project: Research project

  • myocytes 100%
  • smooth muscle 88%
  • gene expression 48%
  • skeletal muscle 36%
  • muscles 32%

• HDAC9, Aging and Alzheimer's Disease

  Weintraub, N. L., LU, X., LU, X. & Weintraub, N.

  National Institute on Aging

  Project: Research project

  • Histone Deacetylases 100%
  • Adipose Tissue 40%
  • Brain 36%
  • Alzheimer Disease 9 21%
  • Adipokines 14%

• Regulation and Function of AKAP12A in the Vessel Wall

  Miano, J. M., Fisher, E., Fisher, E. A. & MIANO, J. M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Vascular Smooth Muscle 100%
  • Smooth Muscle Myocytes 89%
  • Serum Response Factor 44%
  • myocardin 32%
  • Vascular Diseases 19%

• Redox Regulation of Cu Importer CTR1 in Angiogenesis

  Fukai, T. & Fukai, M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Reactive Oxygen Species 100%
  • Endothelial Cells 92%
  • Oxidation-Reduction 68%
  • Vascular Endothelial Growth Factor A 61%
  • Organized Financing 42%

• Targeting the core components of the Hsp90 chaperoning machine

  Chadli, A.

  Project: Research project

  • Molecular Chaperones 100%
  • Neurodegenerative Diseases 70%
  • Humulus 56%
  • Molecular Probes 54%
  • Glucocorticoid Receptors 45%

• A novel therapeutic strategy to eradicate breast cancer through Hsp90 inhibition and reduced immune tolerance

  Chadli, A.

  National Cancer Institute

  Project: Research project

  • HSP90 Heat-Shock Proteins 100%
  • Neoplasms 43%
  • Immune Tolerance 30%
  • Immunotherapy 22%
  • Immune System 20%

• Epigenetic regulation of HDAC9 in obesity and atherosclerosis

  Weintraub, N. L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Histone Deacetylases 100%
  • Obesity 59%
  • Diet 45%
  • Adipose Tissue 33%
  • Atherosclerosis 32%

• Regulation and Function of AKAP12A in the Vessel Wall

  Miano, J. M. & Fisher, E.

  Project: Research project

  • Vascular Smooth Muscle 100%
  • Smooth Muscle Myocytes 89%
  • Serum Response Factor 44%
  • myocardin 32%
  • Vascular Diseases 19%

• Analysis of a Retinoid-Induced Tumor Suppressor in SMC

  Miano, J. M.

  Project: Research project

  • Smooth Muscle Myocytes 100%
  • Retinoids 96%
  • Phosphotransferases 87%
  • Growth 23%
  • Nucleic Acid Regulatory Sequences 21%

• Bifunctionality of Myocardin in Myogenesis

  Miano, J. M. & MIANO, J. M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • myocytes 100%
  • smooth muscle 88%
  • gene expression 48%
  • skeletal muscle 36%
  • muscles 32%

• Role of Smooth Muscle Calponin in Vascular Pathobiology

  Miano, J. M. & MIANO, J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Vascular Smooth Muscle 100%
  • Smooth Muscle Myocytes 89%
  • Clustered Regularly Interspaced Short Palindromic Repeats 38%
  • Vascular Diseases 32%
  • calponin 24%

• Function and Regulation of TSPAN2 in Vascular Disease

  Long, X. & LONG, X.

  Project: Research project

  • Vascular Smooth Muscle 100%
  • Smooth Muscle Myocytes 89%
  • Integrins 34%
  • Phenotype 30%
  • Vascular Diseases 28%

• Mechanisms of myeloperoxidase and Nox4 interactions in abdominal aortic aneurysm

  Weintraub, N. L. & Weintraub, N.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Abdominal Aortic Aneurysm 100%
  • Peroxidase 53%
  • prostaglandin D2 receptor 16%
  • Neutrophil Activation 12%
  • Smooth Muscle Myocytes 8%