Culver Vision Discovery Institute

Research Output 1997 2017

2017
5 Citations (Scopus)

Chloroquine Suppresses the Development of Hypertension in Spontaneously Hypertensive Rats

McCarthy, C. G., Wenceslau, C. F., Goulopoulou, S., Baban, B., Matsumoto, T. & Webb, R. C., Feb 1 2017, In : American journal of hypertension. 30, 2, p. 173-181 9 p.

Research output: Contribution to journalArticle

Chloroquine
Inbred SHR Rats
Hypertension
Mesenteric Arteries
Myeloid Differentiation Factor 88
2016
18 Citations (Scopus)

Anti-inflammatory role of sesamin in STZ induced mice model of diabetic retinopathy

Ahmad, S., ElSherbiny, N. M., Jamal, M. S., Alzahrani, F. A., Haque, R., Khan, R., Zaidi, S. K., AlQahtani, M. H., Liou, G. I. & Bhatia, K., Jun 15 2016, In : Journal of Neuroimmunology. 295-296, p. 47-53 7 p.

Research output: Contribution to journalArticle

Diabetic Retinopathy
Streptozocin
Anti-Inflammatory Agents
Nitric Oxide Synthase Type II
Microglia
5 Citations (Scopus)

Comorbidity in drivers with Parkinson's disease

Ranchet, M., Tant, M., Akinwuntan, A. E., Neal, E. & Devos, H., Feb 1 2016, In : Journal of the American Geriatrics Society. 64, 2, p. 342-346 5 p.

Research output: Contribution to journalArticle

Parkinson Disease
Comorbidity
Physicians
Logistic Models
Drive
2015
13 Citations (Scopus)

Agreement between Physician's Recommendation and Fitness-to-Drive Decision in Multiple Sclerosis

Ranchet, M., Akinwuntan, A. E., Tant, M., Neal, E. & Devos, H., Oct 1 2015, In : Archives of Physical Medicine and Rehabilitation. 96, 10, p. 1840-1844 5 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Physicians
Outcome Assessment (Health Care)
Surveys and Questionnaires
14 Citations (Scopus)

Establishing an evidence-base framework for driving rehabilitation in Parkinson's disease: A systematic review of on-road driving studies

Devos, H., Ranchet, M., Emmanuel Akinwuntan, A. & Uc, E. Y., Aug 22 2015, In : NeuroRehabilitation. 37, 1, p. 35-52 18 p.

Research output: Contribution to journalReview article

Parkinson Disease
Rehabilitation
Library Science
Motor Skills
PubMed
1 Citation (Scopus)

Process-oriented guided-inquiry learning: A natural fit for occupational therapy education

Jaffe, L., Gibson, R. & D'Amico, M., Apr 3 2015, In : Occupational Therapy in Health Care. 29, 2, p. 115-125 11 p.

Research output: Contribution to journalArticle

Occupational Therapy
Learning
Education
Evidence-Based Practice
Teaching
2014
93 Citations (Scopus)

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation

Metz, R., Smith, C., DuHadaway, J. B., Chandler, P., Baban, B., Merlo, L. M. F., Pigott, E., Keough, M. P., Rust, S., Mellor, A. L., Mandik-Nayak, L., Muller, A. J. & Prendergast, G. C., Jul 2014, In : International Immunology. 26, 7, p. 357-367 11 p.

Research output: Contribution to journalArticle

Inflammation
T-Lymphocytes
Kynurenine
Peritoneum
Contact Dermatitis
2013
70 Citations (Scopus)

Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells s tolerogenic responses

Huang, L., Li, L., Lemos, H., Chandler, P. R., Pacholczyk, G., Baban, B., Barber, G. N., Hayakawa, Y., McGaha, T. L., Ravishankar, B., Munn, D. H. & Mellor, A. L., Oct 1 2013, In : Journal of Immunology. 191, 7, p. 3509-3513 5 p.

Research output: Contribution to journalArticle

Myeloid Cells
Dendritic Cells
DNA
Genes
Nanoparticles
21 Citations (Scopus)

Cytokine profiling of young overweight and obese female African American adults with prediabetes

Lucas, R., Parikh, S. J., Sridhar, S., Guo, D. H., Bhagatwala, J., Dong, Y., Caldwell, R., Mellor, A., Caldwell, W., Zhu, H. & Dong, Y., Oct 1 2013, In : Cytokine. 64, 1, p. 310-315 6 p.

Research output: Contribution to journalArticle

Prediabetic State
African Americans
Cytokines
Medical problems
Type 2 Diabetes Mellitus
2012
16 Citations (Scopus)
Vascular Endothelial Growth Factor A
Bone
Bone Regeneration
Tissue
Proteins
44 Citations (Scopus)

Engineering DNA nanoparticles as immunomodulatory reagents that activate regulatory T cells

Huang, L., Lemos, H. P., Li, N., Li, M., Chandler, P. R., Baban, B., McGaha, T. L., Ravishankar, B., Lee, J. R., Munn, D. H. & Mellor, A. L., May 15 2012, In : Journal of Immunology. 188, 10, p. 4913-4920 8 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Polyethyleneimine
Nanoparticles
DNA
Ligands
4 Citations (Scopus)

Invariant recognition of visual objects: Some emerging computational principles

Bart, E. & Hegdé, J., Aug 24 2012, In : Frontiers in Computational Neuroscience. AUGUST

Research output: Contribution to journalArticle

2011
67 Citations (Scopus)

High-mobility group box-1 and biomarkers of inflammation in the vitreous from patients with proliferative diabetic retinopathy

El-Asrar, A. M. A., Nawaz, M. I., Kangave, D., Geboes, K., Ola, M. S., Ahmad, S. & Al-Shabrawey, M., Jul 29 2011, In : Molecular Vision. 17, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

Diabetic Retinopathy
Biomarkers
Inflammation
Retina
Chemokine CCL2
52 Citations (Scopus)

Leishmania major attenuates host immunity by stimulating local indoleamine 2,3-dioxygenase expression

Makala, L. H. C., Baban, B., Lemos, H., El-Awady, A. R., Chandler, P. R., Hou, D. Y., Munn, D. H. & Mellor, A. L., Mar 1 2011, In : Journal of Infectious Diseases. 203, 5, p. 715-725 11 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Leishmania major
Immunity
Infection
T-Lymphocytes
58 Citations (Scopus)

Physiologic control of IDO competence in splenic dendritic cells

Baban, B., Chandler, P. R., Johnson, B. A., Huang, L., Li, M., Sharpe, M. L., Francisco, L. M., Sharpe, A. H., Blazar, B. R., Munn, D. H. & Mellor, A. L., Sep 1 2011, In : Journal of Immunology. 187, 5, p. 2329-2335 7 p.

Research output: Contribution to journalArticle

Mental Competency
Dendritic Cells
T-Lymphocytes
Ligands
Ligation
2010
38 Citations (Scopus)

B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase

Johnson, B. A., Kahler, D. J., Baban, B., Chandler, P. R., Kang, B., Shimoda, M., Koni, P. A., Pihkala, J., Vilagos, B., Busslinger, M., Munn, D. H. & Mellor, A. L., Jun 8 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 23, p. 10644-10648 5 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
Lymphocytes
T-Lymphocytes
Regulatory T-Lymphocytes
75 Citations (Scopus)

Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege

Huang, L., Baban, B., Johnson, B. A. & Mellor, A. L., Mar 1 2010, In : International Reviews of Immunology. 29, 2, p. 133-155 23 p.

Research output: Contribution to journalReview article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
Regulatory T-Lymphocytes
T-Lymphocytes
Immunosuppressive Agents
131 Citations (Scopus)

Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice

Sharma, M. D., Hou, D. Y., Baban, B., Koni, P. A., He, Y., Chandler, P. R., Blazar, B. R., Mellor, A. L. & Munn, D. H., Dec 14 2010, In : Immunity. 33, 6, p. 942-954 13 p.

Research output: Contribution to journalArticle

Cross-Priming
Regulatory T-Lymphocytes
T-Lymphocytes
Indoleamine-Pyrrole 2,3,-Dioxygenase
Antigens
2009
3 Citations (Scopus)

Cannabidiol as a putative novel therapy for diabetic retinopathy: A postulated mechanism of action as an entry point for biomarker-guided clinical development

Liou, G. I., El-Remessy, A. B., Ibrahim, A. S., Caldwell, R. B., Khalifa, Y. M., Gunes, A. & Nussbaum, J. J., Sep 1 2009, In : Current Pharmacogenomics and Personalized Medicine. 7, 3, p. 215-222 8 p.

Research output: Contribution to journalArticle

Cannabidiol
Diabetic Retinopathy
Biomarkers
Retinal Diseases
Precision Medicine
282 Citations (Scopus)

IDO activates regulatory T cells and blocks their conversion into Th17-like T cells

Baban, B., Chandler, P. R., Sharma, M. D., Pihkala, J., Koni, P. A., Munn, D. H. & Mellor, A. L., Aug 15 2009, In : Journal of Immunology. 183, 4, p. 2475-2483 9 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Ligands
T-Lymphocytes
Interleukin-6
Interleukin-17
47 Citations (Scopus)

Targeting the immunoregulatory indoleamine 2,3 dioxygenase pathway in immunotherapy

Johnson, B. A., Baban, B. & L'Mellor, A., Jul 1 2009, In : Immunotherapy. 1, 4, p. 645-661 17 p.

Research output: Contribution to journalReview article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Immunotherapy
Tissue Survival
Immune Tolerance
Dendritic Cells
2007
538 Citations (Scopus)

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

Sharma, M. D., Baban, B., Chandler, P., Hou, D. Y., Singh, N., Yagita, H., Azuma, M., Blazar, B. R., Mellor, A. L. & Munn, D. H., Sep 4 2007, In : Journal of Clinical Investigation. 117, 9, p. 2570-2582 13 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
Lymph Nodes
Neoplasms
CD274 Antigen
27 Citations (Scopus)

Role of CD28 in fatal autoimmune disorder in scurfy mice

Singh, N., Chandler, P. R., Seki, Y., Baban, B., Takezaki, M., Kahler, D. J., Munn, D. H., Larsen, C. P., Mellor, A. L. & Iwashima, M., Aug 15 2007, In : Blood. 110, 4, p. 1199-1206 8 p.

Research output: Contribution to journalArticle

T-cells
T-Lymphocytes
Genes
Mutation
Lymphoproliferative Disorders
2006
13 Citations (Scopus)

Enrichment of regulatory CD4+CD25+ T cells by inhibition of phospholipase D signaling

Singh, N., Seki, Y., Takami, M., Baban, B., Chandler, P. R., Khosravi, D., Zheng, X., Takezaki, M., Lee, J. R., Mellor, A. L., Bollag, W. B. & Iwashima, M., Aug 1 2006, In : Nature Methods. 3, 8, p. 629-636 8 p.

Research output: Contribution to journalArticle

Phospholipase D
T-cells
Regulatory T-Lymphocytes
T-Lymphocytes
Antigen Receptors
2005
149 Citations (Scopus)

A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation

Baban, B., Hansen, A. M., Chandler, P. R., Manlapat, A., Bingaman, A., Kahler, D. J., Munn, D. H. & Mellor, A. L., Jul 1 2005, In : International Immunology. 17, 7, p. 909-919 11 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
Ligation
T-Lymphocytes
Population
237 Citations (Scopus)

Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling

Mellor, A. L., Baban, B., Chandler, P. R., Manlapat, A., Kahler, D. J. & Munn, D. H., Nov 1 2005, In : Journal of Immunology. 175, 9, p. 5601-5605 5 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Oligodeoxyribonucleotides
Regulatory T-Lymphocytes
Oligonucleotides
Dendritic Cells
644 Citations (Scopus)

GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase

Munn, D. H., Sharma, M. D., Baban, B., Harding, H. P., Zhang, Y., Ron, D. & Mellor, A. L., May 1 2005, In : Immunity. 22, 5, p. 633-642 10 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Phosphotransferases
T-Lymphocytes
Dendritic Cells
Transfer RNA
111 Citations (Scopus)

Glucose-dependent insulinotropic polypeptide receptor knockout mice have altered bone turnover

Xie, D., Cheng, H., Hamrick, M., Zhong, Q., Ding, K. H., Correa, D., Williams, S., Mulloy, A., Bollag, W., Bollag, R. J., Runner, R. R., McPherson, J. C., Insogna, K. & Isales, C. M., Dec 1 2005, In : Bone. 37, 6, p. 759-769 11 p.

Research output: Contribution to journalArticle

Bone Remodeling
Knockout Mice
Bone and Bones
Glucose
Peptides
2004
642 Citations (Scopus)

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

Munn, D. H., Sharma, M. D., Hou, D., Baban, B., Lee, J. R., Antonia, S. J., Messina, J. L., Chandler, P., Koni, P. A. & Mellor, A. L., Jan 1 2004, In : Journal of Clinical Investigation. 114, 2, p. 280-290 11 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
Lymph Nodes
T-Lymphocytes
Neoplasms
217 Citations (Scopus)

Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific

Baban, B., Chandler, P., McCool, D., Marshall, B., Munn, D. H. & Mellor, A. L., Apr 1 2004, In : Journal of Reproductive Immunology. 61, 2, p. 67-77 11 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Trophoblasts
Giant Cells
Mothers
Genome
238 Citations (Scopus)

Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase

Mellor, A. L., Chandler, P., Baban, B., Hansen, A. M., Marshall, B., Pihkala, J., Waldmann, H., Cobbold, S., Adams, E. & Munn, D. H., Oct 1 2004, In : International Immunology. 16, 10, p. 1391-1401 11 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Regulatory T-Lymphocytes
Dendritic Cells
T-Lymphocytes
Tryptophan
2003
367 Citations (Scopus)

Cutting edge: Induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion

Mellor, A. L., Baban, B., Chandler, P., Marshall, B., Jhaver, K., Hansen, A., Koni, P. A., Iwashima, M. & Munn, D. H., Aug 15 2003, In : Journal of Immunology. 171, 4, p. 1652-1655 4 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
T-Lymphocyte Subsets
Dendritic Cells
T-Lymphocytes
Adoptive Transfer
42 Citations (Scopus)
Reduced Folate Carrier Protein
Limb Buds
Yolk Sac
Rhombencephalon
Neural Tube
1997
20 Citations (Scopus)

Amidative peptide processing and vascular function

Oldham, C. D., Li, C., Feng, J., Scott, R. O., Wang, W. Z., Moore, A. B., Girard, P. R., Huang, J., Caldwell, R. B., William Caldwell, R. & May, S. W., Dec 1 1997, In : American Journal of Physiology - Cell Physiology. 273, 6 42-6, p. C1908-C1914

Research output: Contribution to journalArticle

Substance P
Blood Vessels
Endothelial cells
Peptides
Nitric Oxide Synthase