Hematology and Oncology

Research Output 1963 2019

Filter
Article
2009
5 Citations (Scopus)

Rare occurrence of Hb Lepore-Baltimore in African Americans: Molecular characteristics and variations of Hb Lepores

McKeown, S. M., Carmichael, H., Markowitz, R-B., Kutlar, A., Holley, L. & Kutlar, F., Jun 1 2009, In : Annals of Hematology. 88, 6, p. 545-548 4 p.

Research output: Contribution to journalArticle

African Americans
Globins
Gene Fusion
beta-Thalassemia
Ethnic Groups
46 Citations (Scopus)

Reactivation of DNA viruses in association with histone deacetylase inhibitor therapy: A case series report

Ritchie, D. S., Piekarz, R. L., Blombery, P., Karai, L. J., Pittaluga, S., Jaffe, E. S., Raffeld, M., Janik, J. E., Miles Prince, H. & Bates, S. E., Nov 1 2009, In : Haematologica. 94, 11, p. 1618-1622 5 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
DNA Viruses
Human Herpesvirus 4
Therapeutics
Peripheral T-Cell Lymphoma
58 Citations (Scopus)

Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury

Adamkiewicz, T. V., Abboud, M. R., Paley, C., Olivieri, N., Kirby-Allen, M., Vichinsky, E., Casella, J. F., Alvarez, O. A., Barredo, J. C., Lee, M. T., Iyer, R. V., Kutlar, A., McKie, K. M., McKie, V., Odo, N., Gee, B., Kwiatkowski, J. L., Woods, G. M., Coates, T., Wang, W. & 1 others, Adams, R. J., Nov 19 2009, In : Blood. 114, 21, p. 4632-4638 7 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Ferritins
Blood Transfusion
Liver
Blood
8 Citations (Scopus)

Strategies to Improve Long-Term Outcome in Stage IIIB Inflammatory Breast Cancer: Multimodality Treatment Including Dose-Intensive Induction and High-Dose Chemotherapy

Sportès, C., Steinberg, S. M., Liewehr, D. J., Gea-Banacloche, J., Danforth, D. N., Avila, D. N., Bryant, K. E., Krumlauf, M. C., Fowler, D. H., Pavletic, S., Hardy, N. M., Bishop, M. R. & Gress, R. E., Aug 1 2009, In : Biology of Blood and Marrow Transplantation. 15, 8, p. 963-970 8 p.

Research output: Contribution to journalArticle

Inflammatory Breast Neoplasms
Cell Transplantation
Drug Therapy
Stem Cells
Disease-Free Survival
1 Citation (Scopus)

Survivin(g) adult T-cell leukemia/lymphoma.

Janik, J. E. & Morris, J. C., Dec 1 2009, In : Oncology (Williston Park, N.Y.). 23, 14

Research output: Contribution to journalArticle

Adult T Cell Leukemia Lymphoma
34 Citations (Scopus)

The carboxyl-terminal domain of Atypical protein kinase Cζ binds to ceramide and regulates junction formation in Epithelial cells

Wang, G., Krishnamurthy, K., Umapathy, N. S., Verin, A. D. & Bieberich, E., May 22 2009, In : Journal of Biological Chemistry. 284, 21, p. 14469-14475 7 p.

Research output: Contribution to journalArticle

Ceramides
Epithelial Cells
Protein Kinases
Madin Darby Canine Kidney Cells
Electric Impedance
39 Citations (Scopus)

Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: A phase III double-blind crossover study (N01CB)

Cheville, A. L., Sloan, J. A., Northfelt, D. W., Jillella, A., Wong, G. Y., Bearden, J. D., Liu, H., Schaefer, P. L., Marchello, B. T., Christensen, B. J. & Loprinzi, C. L., Apr 1 2009, In : Supportive Care in Cancer. 17, 4, p. 451-460 10 p.

Research output: Contribution to journalArticle

Neuralgia
Lidocaine
Double-Blind Method
Cross-Over Studies
Pain
61 Citations (Scopus)

Variable CD52 expression in mature T cell and NK cell malignancies: Implications for alemtuzumab therapy

Jiang, L., Yuan, C. M., Hubacheck, J., Janik, J. E., Wilson, W., Morris, J. C., Jasper, G. A. & Stetler-Stevenson, M., Apr 1 2009, In : British Journal of Haematology. 145, 2, p. 173-179 7 p.

Research output: Contribution to journalArticle

T-Cell Lymphoma
Natural Killer Cells
Natural Killer T-Cells
T-Lymphocytes
Prolymphocytic Leukemia
2010
12 Citations (Scopus)

Acute myelogenous leukemia patients are at low risk for invasive fungal infections after high-dose cytarabine consolidations and thus do not require prophylaxis

Lewis, G., Hall, P., Eisa, N., Deremer, D., Dobbins, R., El-Geneidy, M., Jillella, A. & Ustun, C., Dec 1 2010, In : Acta Haematologica. 124, 4, p. 206-213 8 p.

Research output: Contribution to journalArticle

Fluconazole
Cytarabine
Acute Myeloid Leukemia
Control Groups
Fever
2 Citations (Scopus)

A new sickling variant 'Hb S-Wake β[(Glu6Val-Asn139 Ser)]' found in a compound heterozygote with Hb S β(Glu6Val) coinherited with homozygous α-thalassemia-2: Phenotype and molecular characteristics

Kutlar, F., Redding-Lallinger, R., Meiler, S. E., Bakanay, S. M., Borders, L. & Kutlar, A., Oct 1 2010, In : Acta Haematologica. 124, 2, p. 120-124 5 p.

Research output: Contribution to journalArticle

Thalassemia
Heterozygote
Alleles
Phenotype
Mutation
20 Citations (Scopus)

Anti-proliferative and anti-cancer properties of Achyranthes aspera: Specific inhibitory activity against pancreatic cancer cells

Subbarayan, P. R., Sarkar, M., Impellizzeri, S., Raymo, F., Lokeshwar, B. L., Kumar, P., Agarwal, R. P. & Ardalan, B., Aug 1 2010, In : Journal of Ethnopharmacology. 131, 1, p. 78-82 5 p.

Research output: Contribution to journalArticle

Achyranthes
Pancreatic Neoplasms
Silica Gel
Methanol
Neoplasms
26 Citations (Scopus)

Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemia

Chen, J., Petrus, M., Bryant, B. R., Nguyen, V. P., Goldman, C. K., Bamford, R., Morris, J. C., Janik, J. E. & Waldmann, T. A., Dec 23 2010, In : Blood. 116, 26, p. 5948-5956 9 p.

Research output: Contribution to journalArticle

T-Cell Prolymphocytic Leukemia
Adult T Cell Leukemia Lymphoma
T-cells
Cell proliferation
Interleukin-9
10 Citations (Scopus)

CD44 and p53 immunoexpression patterns in NF1 neoplasms - indicators of malignancy and infiltration

Riddle, N. D., Gorden, L., Rojiani, M. V., Hakam, A. & Rojiani, A. M., Sep 2 2010, In : International Journal of Clinical and Experimental Pathology. 3, 5, p. 515-521 7 p.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Neurofibroma
Neurilemmoma
Neoplasms
Plexiform Neurofibroma
Cell Proliferation
Proteins
Minichromosome Maintenance Proteins
Palatine Tonsil
Cell Extracts
47 Citations (Scopus)

Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype

Ding, Z. C., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Mar 25 2010, In : Blood. 115, 12, p. 2397-2406 10 p.

Research output: Contribution to journalArticle

Chemotherapy
T-cells
Tumors
Cell Differentiation
T-Lymphocytes
9 Citations (Scopus)

Correlation of pretransplant and early post-transplant response assessment with outcomes after reduced-intensity allogeneic hematopoietic stem cell transplantation for non-Hodgkin's lymphoma

Bishop, M. R., Dean, R. M., Steinberg, S. M., Odom, J., Pollack, S. M., Pavletic, S. Z., Sportes, C., Gress, R. E. & Fowler, D. H., Feb 15 2010, In : Cancer. 116, 4, p. 852-862 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Non-Hodgkin's Lymphoma
Outcome Assessment (Health Care)
Transplants
Disease-Free Survival
33 Citations (Scopus)

DNA prime-protein boost increased the titer, avidity and persistence of anti-AΒ antibodies in wild-type mice

Davtyan, H., Mkrtichyan, M., Movsesyan, N., Petrushina, I., Mamikonyan, G., Cribbs, D. H., Agadjanyan, M. G. & Ghochikyan, A., Feb 1 2010, In : Gene Therapy. 17, 2, p. 261-271 11 p.

Research output: Contribution to journalArticle

Recombinant Proteins
Anti-Idiotypic Antibodies
DNA Vaccines
Alzheimer Vaccines
Epitopes
697 Citations (Scopus)

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

Kochenderfer, J. N., Wilson, W. H., Janik, J. E., Dudley, M. E., Stetler-Stevenson, M., Feldman, S. A., Maric, I., Raffeld, M., Nathan, D. A. N., Lanier, B. J., Morgan, R. A. & Rosenberg, S. A., Nov 18 2010, In : Blood. 116, 20, p. 4099-4102 4 p.

Research output: Contribution to journalArticle

CD19 Antigens
T-cells
Antigen Receptors
Lymphoma
T-Cell Antigen Receptor
56 Citations (Scopus)

Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma

Rojiani, M. V., Alidina, J., Esposito, N. & Rojiani, A. M., Dec 1 2010, In : International Journal of Clinical and Experimental Pathology. 3, 8, p. 775-781 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Central Nervous System
Neoplasm Metastasis
Carcinoma
Lung
21 Citations (Scopus)

Gene silencing of BAG-1 modulates apoptotic genes and sensitizes lung cancer cell lines to cisplatin-induced apoptosis

Liu, H., Liang, Y., Li, Y., Li, Y., Wang, J., Wu, H., Wang, Y., Tang, S. C., Chen, J. & Zhou, Q., May 15 2010, In : Cancer Biology and Therapy. 9, 10, p. 832-840 9 p.

Research output: Contribution to journalArticle

Open Access
Gene Silencing
Cisplatin
Lung Neoplasms
Apoptosis
Cell Line
11 Citations (Scopus)

Inhibition of endothelial nitric oxide synthase by the lipid phosphatase PTEN

Church, J. E., Qian, J., Kumar, S., Black, S. M., Venema, R. C., Papapetropoulos, A. & Fulton, D. J. R., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 191-198 8 p.

Research output: Contribution to journalArticle

PTEN Phosphohydrolase
Nitric Oxide Synthase Type III
Phosphorylation
Lipids
1-Phosphatidylinositol 4-Kinase
7 Citations (Scopus)

Low concentrations of anti-Aβ antibodies generated in Tg2576 mice by DNA epitope vaccine fused with 3C3d molecular adjuvant do not affect AD pathology

Movsesyan, N., Davtyan, H., Mkrtichyan, M., Petrushina, I., Tiraturyan, T., Ross, T., Agadjanyan, M. G., Ghochikyan, A. & Cribbs, D. H., Nov 1 2010, In : Human Gene Therapy. 21, 11, p. 1569-1576 8 p.

Research output: Contribution to journalArticle

DNA Vaccines
Epitopes
Anti-Idiotypic Antibodies
Alzheimer Disease
Vaccines
31 Citations (Scopus)

Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: Role of asymmetric dimethylarginine

Sharma, S., Smith, A., Kumar, S., Aggarwal, S., Rehmani, I., Snead, C., Harmon, C., Fineman, J., Fulton, D. J., Catravas, J. D. & Black, S. M., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 182-190 9 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Endotoxins
Nitric Oxide Synthase
Lipopolysaccharides
Lung
14 Citations (Scopus)

Minimal residual disease detection by flow cytometry in adult T-cell leukemia/lymphoma

Shao, H., Yuan, C. M., Xi, L., Raffeld, M., Morris, J. C., Janik, J. E. & Stetler-Stevenson, M., Apr 1 2010, In : American Journal of Clinical Pathology. 133, 4, p. 592-601 10 p.

Research output: Contribution to journalArticle

Adult T Cell Leukemia Lymphoma
Residual Neoplasm
Flow Cytometry
T-Lymphocytes
Gene Rearrangement
29 Citations (Scopus)

Molecular mechanisms involved in adenosine-induced endothelial cell barrier enhancement

Siddaramappa, U. N., Fan, Z. H., Zemskov, E. A., Alieva, I. B., Black, S. M. & Verin, A. D., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 199-206 8 p.

Research output: Contribution to journalArticle

Adenosine
Endothelial Cells
Electric Impedance
Pulmonary Artery
Small Interfering RNA
143 Citations (Scopus)

Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia

Vichinsky, E. P., Neumayr, L. D., Gold, J. I., Weiner, M. W., Rule, R. R., Truran, D., Kasten, J., Eggleston, B., Kesler, K., McMahon, L., Orringer, E. P., Harrington, T., Kalinyak, K., De Castro, L. M., Kutlar, A., Rutherford, C. J., Johnson, C., Bessman, J. D., Jordan, L. B. & Armstrong, F. D., May 12 2010, In : JAMA - Journal of the American Medical Association. 303, 18, p. 1823-1831 9 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Neuroimaging
Confidence Intervals
Executive Function
Intelligence
3 Citations (Scopus)
Plasmids
Anti-Bacterial Agents
Stem Cells
Cell Lineage
Embryonic Stem Cells
13 Citations (Scopus)

Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow

Sharma, S., Kumar, S., Wiseman, D. A., Kallarackal, S., Ponnala, S., Elgaish, M., Tian, J., Fineman, J. R. & Black, S. M., Jul 1 2010, In : Vascular Pharmacology. 53, 1-2, p. 38-52 15 p.

Research output: Contribution to journalArticle

Xanthine Oxidase
Superoxides
Sheep
NADP
Oxidoreductases
123 Citations (Scopus)

Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy

Sportès, C., Babb, R. R., Krumlauf, M. C., Hakim, F. T., Steinberg, S. M., Chow, C. K., Brown, M. R., Fleisher, T. A., Noel, P., Maric, I., Stetler-Stevenson, M., Engel, J., Buffet, R., Morre, M., Amato, R. J., Pecora, A., Mackall, C. L. & Gress, R. E., Jan 15 2010, In : Clinical Cancer Research. 16, 2, p. 727-735 9 p.

Research output: Contribution to journalArticle

Interleukin-7
B-Lymphoid Precursor Cells
Neoplasms
Human Activities
T-Lymphocytes
20 Citations (Scopus)

Plasma interleukin-1β concentration is associated with stroke in sickle cell disease

Asare, K., Gee, B. E., Stiles, J. K., Wilson, N. O., Driss, A., Quarshie, A., Adams, R. J., Kutlar, A. & Hibbert, J. M., Jan 1 2010, In : Cytokine. 49, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Interleukin-1
Stroke
Plasmas
Ultrasonics
2 Citations (Scopus)

Posterior segment ophthalmic complications of aplastic anemia.

Agarwal, M., Yeh, S., Faia, L. J., Bishop, R. J., Lai, M. M., Pantin, J. M., Scheinberg, P., Chew, E. Y. & Weichel, E. D., Jan 1 2010, In : Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye. 41 Online

Research output: Contribution to journalArticle

Aplastic Anemia
Vitrectomy
Vitreous Hemorrhage
Temazepam
Visual Acuity
36 Citations (Scopus)
Catalase
Protein Kinase C
Nitric Oxide
Endothelial Cells
Phosphorylation
22 Citations (Scopus)

Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter

Miyauchi, S., Gopal, E., Babu, E., Srinivas, S. R., Kubo, Y., Siddaramappa, U. N., Thakkar, S. V., Ganapathy, V. & Prasad, P. D., Jun 1 2010, In : Biochimica et Biophysica Acta - Biomembranes. 1798, 6, p. 1164-1171 8 p.

Research output: Contribution to journalArticle

Pyrrolidonecarboxylic Acid
Sodium
Amino Acid Transport Systems
Chemical activation
Oocytes
23 Citations (Scopus)

The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - A crucial role for protein kinase C-α inhibition

Xiong, C., Yang, G., Kumar, S., Aggarwal, S., Leustik, M., Snead, C., Hamacher, J., Fischer, B., Siddaramappa, U. N., Hossain, H., Wendel, A., Catravas, J. D., Verin, A. D., Fulton, D. J., Black, S. M., Chakraborty, T. & Lucas, R., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 207-213 7 p.

Research output: Contribution to journalArticle

Lectins
Protein Kinase C
Myosin Light Chains
Endothelial Cells
Lung
29 Citations (Scopus)

The lectin-like doMain of tumor necrosis factor improves lung function after rat lung transplantation-Potential role for a reduction in reactive oxygen species generation

Hamacher, J., Stammberger, U., Roux, J., Kumar, S., Yang, G., Xiong, C., Schmid, R. A., Fakin, R. M., Chakraborty, T., Hossain, H. M. D., Pittet, J. F., Wendel, A., Black, S. M. & Lucas, R., Mar 2010, In : Critical care medicine. 38, 3, p. 871-878 8 p.

Research output: Contribution to journalArticle

Lung Transplantation
Lectins
Reactive Oxygen Species
Tumor Necrosis Factor-alpha
Lung
255 Citations (Scopus)

The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up

Steinberg, M. H., McCarthy, W. F., Castro, O., Ballas, S. K., Armstrong, F. D., Smith, W., Ataga, K., Swerdlow, P., Kutlar, A., DeCastro, L., Waclawiw, M. A., Orringer, E., Jones, S., Strayhorn, D., Rosse, W., Phillips, G., Peace, D., Johnson-Telfair, A., Daitch, L. H., Milner, P. & 91 others, Tracy, A., Valdez, S., Allen, G. E., Moshang, J., Scott, B., Bigelow, C., Anderson, A., Sabahi, V., Harrington, T., Labrousse, W., Pegelow, C., Temple, D., Case, E., Harrell, R., Childerie, S., Embury, S., Schmidt, B., Davies, D., Saunthararajah, Y., Koshy, M., Talischy-Zahed, N., Dorn, L., Pendarvis, G., McGee, M., Telfer, M., Davis, A., Onyekwere, O. C., Nwokolo, C., Finke, H., Perlin, E., Siteman, J., Bryan, M., Saunders, T., Barber, Y., Gascon, P., Di Paolo, P., Gargiulo, S., Eckman, J., Carter-Randall, E., Bailey, J. H., Platt, A., Waller, L., Ramirez, G., Knors, V., Hernandez, S., Rodriguez, E. M., Wilkes, E., Vichinsky, E., Hagar, W., Hoehner, C., Hackney-Stevens, E., Claster, S., Earles, A., Kleman, K., McLaughlin, K., White, L., Maddox, B., Usry, L., Brenner, A., Williams, K., O'Brien, R., Genther, K., Shurin, S., Berman, B., Chiarucci, K., Keverline, L., Olivieri, N., Chow, J., Hui, M., Shaw, D., Lewis, N., Okam, M., Mandell, E., Palmer, A., Bridges, K., Tynan, B., Winograd, C., Bellevue, R., Dosik, H., Sheikhai, M., Ryans, P., Souffrant, H., Adler, B., Johnson-Telfair, A., Eskridge, L., Prchal, J., Braddock, J., McArdle, T., Carlos, T., Roundtree-Schmotzer, A. & Gardner, D., Jun 1 2010, In : American Journal of Hematology. 85, 6, p. 403-408 6 p.

Research output: Contribution to journalArticle

Hydroxyurea
Sickle Cell Anemia
Mortality
Withholding Treatment
Cohort Studies
5 Citations (Scopus)

Visual inspection versus quantitative flow cytometry to detect aberrant CD2 expression in malignant T cells

Arun, I., Wulu, J. A., Janik, J. E., Jasper, G. A., Yuan, C. M., Venzon, D. & Stetler-Stevenson, M., May 1 2010, In : Cytometry Part B - Clinical Cytometry. 78, 3, p. 169-175 7 p.

Research output: Contribution to journalArticle

Flow Cytometry
T-Lymphocytes
Antibodies
Neoplasms
Reference Values
2011
8 Citations (Scopus)

Adult T-cell leukemia/lymphoma with Epstein-Barr virus-positive Hodgkin-like cells

Venkataraman, G., Berkowitz, J., Morris, J. C., Janik, J. E., Raffeld, M. A. & Pittaluga, S., Jul 1 2011, In : Human Pathology. 42, 7, p. 1042-1046 5 p.

Research output: Contribution to journalArticle

Adult T Cell Leukemia Lymphoma
Human Herpesvirus 4
Hodgkin Disease
Lymphoproliferative Disorders
B-Lymphocytes
85 Citations (Scopus)
Arginase
rho-Associated Kinases
p38 Mitogen-Activated Protein Kinases
Angiotensin II
Blood Vessels
100 Citations (Scopus)

Anti-PD-1 synergizes with cyclophosphamide to induce potent anti-tumor vaccine effects through novel mechanisms

Mkrtichyan, M., Najjar, Y. G., Raulfs, E. C., Abdalla, M. Y., Samara, R., Rotem-Yehudar, R., Cook, L. & Khleif, S. N., Oct 1 2011, In : European Journal of Immunology. 41, 10, p. 2977-2986 10 p.

Research output: Contribution to journalArticle

Death Domain Receptors
Cancer Vaccines
Regulatory T-Lymphocytes
Cyclophosphamide
T-Lymphocytes
122 Citations (Scopus)

Association of genetic variation with systolic and diastolic blood pressure among african americans: The candidate gene association resource study

Fox, E. R., Young, J. H., Li, Y., Dreisbach, A. W., Keating, B. J., Musani, S. K., Liu, K., Morrison, A. C., Ganesh, S., Kutlar, A., Ramachandran, V. S., Polak, J. F., Fabsitz, R. R., Dries, D. L., Farlow, D. N., Redline, S., Adeyemo, A., Hirschorn, J. N., Sun, Y. V., Wyatt, S. B. & 23 others, Penman, A. D., Palmas, W., Rotter, J. I., Townsend, R. R., Doumatey, A. P., Tayo, B. O., Mosley, T. H., Lyon, H. N., Kang, S. J., Rotimi, C. N., Cooper, R. S., Franceschini, N., Curb, J. D., Martin, L. W., Eaton, C. B., Kardia, S. L. R., Taylor, H. A., Caulfield, M. J., Ehret, G. B., Johnson, T., Chakravarti, A., Zhu, X. & Levy, D., Jun 1 2011, In : Human Molecular Genetics. 20, 11, p. 2273-2284 12 p., ddr092.

Research output: Contribution to journalArticle

Genetic Association Studies
African Americans
Blood Pressure
Genes
Genome-Wide Association Study
18 Citations (Scopus)

Cancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma

Mkrtichyan, M., Ghochikyan, A., Davtyan, H., Movsesyan, N., Loukinov, D., Lobanenkov, V., Cribbs, D. H., Laust, A. K., Nelson, E. L. & Agadjanyan, M. G., Jun 6 2011, In : Cellular Immunology. 270, 2, p. 188-197 10 p.

Research output: Contribution to journalArticle

Testicular Neoplasms
Dendritic Cells
Vaccines
Breast Neoplasms
Antigens
38 Citations (Scopus)
Tetracyclines
Pharmaceutical Preparations
Neoplasms
Matrix Metalloproteinases
Apoptosis
59 Citations (Scopus)

Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: Contributions from the CARe consortium

Zhu, X., Young, J. H., Fox, E., Keating, B. J., Franceschini, N., Kang, S., Tayo, B., Adeyemo, A., Sun, Y. V., Li, Y., Morrison, A., Newton-Cheh, C., Liu, K., Ganesh, S. K., Kutlar, A., Vasan, R. S., Dreisbach, A., Wyatt, S., Polak, J., Palmas, W. & 19 others, Musani, S., Taylor, H., Fabsitz, R., Townsend, R. R., Dries, D., Glessner, J., Chiang, C. W. K., Mosley, T., Kardia, S., Curb, D., Hirschhorn, J. N., Rotimi, C., Reiner, A., Eaton, C., Rotter, J. I., Cooper, R. S., Redline, S., Chakravarti, A. & Levy, D., Jun 1 2011, In : Human Molecular Genetics. 20, 11, p. 2285-2295 11 p., ddr113.

Research output: Contribution to journalArticle

Genetic Loci
Blood Pressure
Genes
African Americans
Single Nucleotide Polymorphism
48 Citations (Scopus)

CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients withATL and HAM/TSP

Ju, W., Zhang, M., Jiang, J. K., Thomas, C. J., Oh, U., Bryant, B. R., Chen, J., Sato, N., Tagaya, Y., Morris, J. C., Janik, J. E., Jacobson, S. & Waldmann, T. A., Feb 10 2011, In : Blood. 117, 6, p. 1938-1946 9 p.

Research output: Contribution to journalArticle

Janus Kinase 3
Tropical Spastic Paraparesis
T-cells
Adult T Cell Leukemia Lymphoma
Chemical activation
16 Citations (Scopus)

C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow

Sun, X., Fratz, S., Sharma, S., Hou, Y., Rafikov, R., Kumar, S., Rehmani, I., Tian, J., Smith, A., Schreiber, C., Reiser, J., Naumann, S., Haag, S., Hess, J., Catravas, J. D., Patterson, C., Fineman, J. R. & Black, S. M., Jul 1 2011, In : American journal of respiratory cell and molecular biology. 45, 1, p. 163-171 9 p.

Research output: Contribution to journalArticle

GTP Cyclohydrolase
HSP70 Heat-Shock Proteins
Guanosine
Guanosine Triphosphate
Blood
28 Citations (Scopus)

Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms

Dos Santos, J. L., Lanaro, C., Lima, L. M., Gambero, S., Franco-Penteado, C. F., Alexandre-Moreira, M. S., Wade, M., Yerigenahally, S., Kutlar, A., Meiler, S. E., Costa, F. F. & Chung, M., Aug 25 2011, In : Journal of Medicinal Chemistry. 54, 16, p. 5811-5819 9 p.

Research output: Contribution to journalArticle

Hydroxyurea
Sickle Cell Anemia
Tumor Necrosis Factor-alpha
Pharmacology
Thalidomide
18 Citations (Scopus)

Disseminated Strongyloides stercoralis infection in HTLV-1-associated adult T-cell leukemia/lymphoma

Stewart, D. M., Ramanathan, R., Mahanty, S., Fedorko, D. P., Janik, J. E. & Morris, J. C., Aug 1 2011, In : Acta Haematologica. 126, 2, p. 63-67 5 p.

Research output: Contribution to journalArticle

Strongyloides stercoralis
Adult T Cell Leukemia Lymphoma
Human T-lymphotropic virus 1
T-Lymphocytes
Adrenal Cortex Hormones
128 Citations (Scopus)

eNOS activation and NO function: Structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity

Rafikov, R., Fonseca, F. V., Kumar, S., Pardo, D., Darragh, C., Elms, S., Fulton, D. & Black, S. M., Sep 1 2011, In : Journal of Endocrinology. 210, 3, p. 271-284 14 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Nucleic Acid Regulatory Sequences
Post Translational Protein Processing
Superoxides
Oxidative Stress
58 Citations (Scopus)

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

Elliott, N. E., Cleveland, S. M., Grann, V., Janik, J., Waldmann, T. A. & Davé, U. P., Oct 6 2011, In : Blood. 118, 14, p. 3911-3921 11 p.

Research output: Contribution to journalArticle

Adult T Cell Leukemia Lymphoma
T-cells
Mutation
Chemotherapy
Genetic Association Studies