Hematology and Oncology

Research Output 1963 2019

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1989
6 Citations (Scopus)

HB j-Lome or α2β259(e3)LYS→ASN in a vietnamese family

Prior, J. F., Raven, J. L., Wilson, J. B., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 1, p. 79-81 3 p.

Research output: Contribution to journalArticle

Hemoglobin J
Abnormal Hemoglobins
DEAE-Cellulose Chromatography
Vietnam
31 Citations (Scopus)

HB monroe or α2β230(b12)ARG→THR, a variant associated with βthalassemia due to a g→c substitution adjacent to the donor splice site of the first intron

Gonzalez-Redondo, J. M., Stoming, T. A., Kutlar, F., Kutlar, A., Hu, H., Wilson, J. B. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Abnormal Hemoglobins
RNA Splice Sites
Thalassemia
Gene Rearrangement
14 Citations (Scopus)

Hydrops fetalis due to homozygosity for α-thalassemia-1, -(α)-20.5 kb: The first observation in a Turkish family

Gurgey, A., Altay, Beksaç, M. S., Bhattacharya, R., Kutlar, F. & Huisman, T. H. J., Jan 1 1989, In : Acta Haematologica. 81, 3, p. 169-171 3 p.

Research output: Contribution to journalArticle

Hydrops Fetalis
Thalassemia
Globins
Chromosome Mapping
Fetus
7 Citations (Scopus)

Mechanisms for the stimulation of prostanoid synthesis by cyclosporine and bacterial lipopolysacch aride

Zhang, H., Kaseki, H., Davis, W. B., Whisler, R. L. & Cornwell, D. G., Jan 1 1989, In : Transplantation. 47, 5, p. 864-871 8 p.

Research output: Contribution to journalArticle

Arachidonic Acid
Cyclosporine
Prostaglandins
Calcimycin
Prostaglandin-Endoperoxide Synthases
2 Citations (Scopus)

Mild sickle cell anemia associated with alpha globin mutant alpha montgomery

Prchal, J. T., Scott, C. M., Rahbar, S., Nagel, R. L., Kutlar, A., Galla, J. H. & Hall, K., 1989, In : The American Journal of Medicine. 86, 2 C, p. 232-236 5 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Molecular characterization of β‐globin gene mutations in Malay patients with Hb E‐β‐thalassaemia and thalassaemia major

Yang, K. G., Kutlar, F., George, E., Wilson, J. B., Kutlar, A., Stoming, T. A., Redondo, J. M. G. & Huisman, T. H. J., May 1989, In : British Journal of Haematology. 72, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

Globins
beta-Thalassemia
Codon
Thalassemia
Mutation
20 Citations (Scopus)

Molecular heterogeneity of beta-thalassemia intermedia in turkey

Gurgey, A., Altay, Diaz-Chico, J. C., Kutlar, F., Kutlar, A. & Huisman, T. H. J., Jan 1 1989, In : Acta Haematologica. 81, 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

beta-Thalassemia
Thalassemia
Codon
Mutation
Genetic Association Studies
19 Citations (Scopus)

Normal Fetal Hemoglobin Levels in the Sudden Infant Death Syndrome

Zielke, H. R., Meny, R. G., O'brien, M. J., Smialek, J. E., Kutlar, F., Huisman, T. H. J. & Dover, G. J., Nov 16 1989, In : New England Journal of Medicine. 321, 20, p. 1359-1364 6 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Sudden Infant Death
Fluorescent Antibody Technique
Cause of Death
Parents
12 Citations (Scopus)

Quantitation of hemoglobins Bart's, H, Portland-I, Portland-II and constant spring by anion-exchange high-performance liquid chromatography

Kutlar, F., Gu, L. H., Hu, H. & Huisman, T. H. J., Jan 1 1989, In : Journal of Chromatography B: Biomedical Sciences and Applications. 487, C, p. 265-274 10 p.

Research output: Contribution to journalArticle

Hemoglobin H
High performance liquid chromatography
Anions
Blood
Abnormal Hemoglobins
41 Citations (Scopus)

Severe Hb S-β°-thalassaemia with a T→C substitution in the donor splice site of the first intron of the β-globin gene

Gonzalez-Redondo, J. M., Stoming, T. A., Kutlar, F., Kutlar, A., McKie, V. C., McKie, K. M. & Huisman, T. H. J., Jan 1 1989, In : British Journal of Haematology. 71, 1, p. 113-117 5 p.

Research output: Contribution to journalArticle

RNA Splice Sites
Thalassemia
Globins
Introns
Genes
17 Citations (Scopus)

Studies on oxidized low density lipoproteins. Controlled oxidation and a prostaglandin artifact

Zhang, H., Davis, W. B., Chen, X., Whisler, R. L. & Cornwell, D. G., Jan 1 1989, In : Journal of Lipid Research. 30, 2, p. 141-148 8 p.

Research output: Contribution to journalArticle

LDL Lipoproteins
Artifacts
Prostaglandins
Lipoproteins
Oxidation
32 Citations (Scopus)

The levels of ζ, γ, and δ chains in patients with Hb H disease

Kutlar, F., Gonzalez-Redondo, J. M., Kutlar, A., Gurgey, A., Altay, Ç., Efremov, G. D., Kleman, K. & Huisman, T. H. J., May 1 1989, In : Human Genetics. 82, 2, p. 179-186 8 p.

Research output: Contribution to journalArticle

RNA Splice Sites
Globins
Far East
Hemolytic Anemia
Gene Deletion
14 Citations (Scopus)

The types of hemoglobins and globin chains in hydrops fetalis

Kutlar, F., Reese, A. L., Hsia, Y. E., Kleman, K. M. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 7-8, p. 671-683 13 p.

Research output: Contribution to journalArticle

Hydrops Fetalis
Globins
Hemoglobins
Cells
Blood
6 Citations (Scopus)

Two rare unstable β chain variants, HB mozhaisk or α2β292(f8)his ARG and HB DJELFA or α2β298(FG5)VAL→ALA, each being observed for the second time

Bird, A. R., Elliott, T., Wison, J. B., Webber, B. B., Hu, H., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 2, p. 193-197 5 p.

Research output: Contribution to journalArticle

Cellulose Acetate Electrophoresis
Abnormal Hemoglobins
Amino Acid Sequence
High Pressure Liquid Chromatography

α‐thalassemia among Pediatric Hemoglobin S Homozygotes: Molecular and Clinical Studies

FELICE, A. E., ZHAO, J., KUTLAR, A., RHODES, M., McKie, K. & McKie, V., Jul 1989, In : Annals of the New York Academy of Sciences. 565, 1, p. 381-382 2 p.

Research output: Contribution to journalArticle

Sickle Hemoglobin
alpha-Thalassemia
Homozygote
Pediatrics
Clinical Studies
18 Citations (Scopus)

βthalassemia intermedia in two turkish families is caused by the interaction of HB knossos [β27(b9)ALA→SER] and of HB city of Hope [β69(e13)gly→ser] with b°thalassemia

Kutlar, A., Kutlar, F., Aksoy, M., Gurgey, A., Altay, C., Wilson, J. B., Diaz-Chico, J. C., Hu, H. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 1, p. 7-16 10 p.

Research output: Contribution to journalArticle

Thalassemia
beta-Thalassemia
Abnormal Hemoglobins
Oligonucleotide Probes
High performance liquid chromatography
1990
9 Citations (Scopus)

Chinese in west Malaysia: the geography of beta thalassaemia mutations.

George-Kodiseri, E., Yang, K. G., Kutlar, F., Wilson, J. B., Kutlar, A., Stoming, T. A., Gonzales-Redondo, J. M. & Huisman, T. H., Jan 1 1990, In : Singapore Medical Journal. 31, 4, p. 374-377 4 p.

Research output: Contribution to journalArticle

Geography
beta-Thalassemia
Malaysia
Mutation
Codon
5 Citations (Scopus)

Compound heterozygosity for a mild β+ and a rare β0-thalassemia allele

Codrington, J., Anijs, J., Wisse, J. H., Codrington, F. A., Li, H., Kutlar, F., Ramachandran, M. & Huisman, T. H. J., Jan 1 1990, In : Acta Haematologica. 84, 3, p. 135-138 4 p.

Research output: Contribution to journalArticle

Thalassemia
Heterozygote
Alleles
Mutation
Suriname
109 Citations (Scopus)

Effects of oxidatively modified LDL on cholesterol esterification in cultured macrophages

Zhang, H., Basra, H. J. K. & Steinbrecher, U. P., Jan 1 1990, In : Journal of Lipid Research. 31, 8, p. 1361-1369 9 p.

Research output: Contribution to journalArticle

Macrophages
Esterification
LDL Lipoproteins
LDL Cholesterol
Cholesterol
20 Citations (Scopus)

Effects of oxidized low density liporoteins on arachidonic acid metabolism in smooth muscle cells

Zhang, H., Davis, W. B., Chen, X., Jones, K. H., Whisler, R. L. & Cornwell, D. G., Jan 1 1990, In : Journal of Lipid Research. 31, 4, p. 551-565 15 p.

Research output: Contribution to journalArticle

Arachidonic Acid
Metabolism
Smooth Muscle Myocytes
Muscle
Prostaglandins
118 Citations (Scopus)

Fetal hemoglobin in normal adults and β-thalassemia heterozygotes

Kutlar, A., Kutlar, F., Gu, L. G., Mayson, S. M. & Huisman, T. H. J., Jun 1 1990, In : Human Genetics. 85, 1, p. 106-110 5 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Thalassemia
Heterozygote
Mutation
Codon
6 Citations (Scopus)

Growth factor-dependent regulation of transferrin receptor in proliferating and quiescent macrophages

Lokeshwar, B. L. & Lin, H. S., Oct 15 1990, In : Cellular Immunology. 130, 2, p. 401-415 15 p.

Research output: Contribution to journalArticle

Transferrin Receptors
Intercellular Signaling Peptides and Proteins
Macrophages
Macrophage Colony-Stimulating Factor
Colony-Stimulating Factor Receptors
4 Citations (Scopus)

Hb f-Brooklyn or α2gγ266(e10)LYSGLN

Plaseska, D., Li, H. J., Wilson, J. B., Kutlar, F., Kutlar, A., Huisman, T. H. J. & Kulpa, J., Jan 1 1990, In : Hemoglobin. 14, 2, p. 213-216 4 p.

Research output: Contribution to journalArticle

Hemoglobins
Blood
Abnormal Hemoglobins
Electrophoresis
Screening
4 Citations (Scopus)

Hb f-catala or α2gy2l5(a12)trp →arg

Plaseska, D., Wilson, J. B., Kutlar, F., Font, L., Baiget, H. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 5, p. 511-516 6 p.

Research output: Contribution to journalArticle

compound A 12
Spain
Substitution reactions
Amino Acids
Liquids
11 Citations (Scopus)

Hb f-charlotte, an aγ variant with a threonine residue in position γ75 and a glycine residue in position γ136

Plaseska, D., Kutlar, F., Wilson, J. B., Fei, Y. J. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 6, p. 617-625 9 p.

Research output: Contribution to journalArticle

Threonine
Glycine
Blood
Substitution reactions
Genes
4 Citations (Scopus)

Hb f-jiangsu, the first γ chain variant with a valine -methionine substitution: Αgamma;2134(h12) val→met

Plaseska, D., Kutlar, F., Wilson, J. B., Webber, B. B., Zeng, Y. T. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

methionylmethionine
Valine
Fetal Blood
Methionine
Substitution reactions
4 Citations (Scopus)

Hb f-onoda or α2gγ2146(HC3)histyr a newly discovered fetal hemoglobin variant in a japanese newborn

Harano, T., Harano, K., Doi, K., Ueda, S., Imai, K., Ohba, Y., Kutlar, F. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 2, p. 217-222 6 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Gene Order
Globins
High performance liquid chromatography
Reverse-Phase Chromatography
13 Citations (Scopus)

Hb Hekinan observed in three chinese from macau; identification of the gag→gat mutation in the αl-globin gene

Zhao, W., Wilson, J. B., Webber, B. B., Kutlar, A., Tamagnini, G. P., Kuan, B. & Huisnan, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 6, p. 627-635 9 p.

Research output: Contribution to journalArticle

Macau
Globins
High performance liquid chromatography
Aspartic Acid
Purification
7 Citations (Scopus)

Hb lepore-Baltimore in a north sardinian family

Nasala, B., Manca, L., Wilson, J. B., Webber, B. B., Kutlar, A. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 3, p. 241-246 6 p.

Research output: Contribution to journalArticle

Abnormal Hemoglobins
Italy
Amino Acids
hemoglobin Lepore Baltimore
26 Citations (Scopus)

Hb sun prae or α213o(h13)ala → proβ2 a new unstable variant occurring in low quantities

Harkness, M., Harkness, D. R., Kutlar, F., Kutlar, A., Wilson, J. B., Webber, B. B., Codrington, J. F. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 5, p. 479-489 11 p.

Research output: Contribution to journalArticle

Solar System
Sun
Globins
Genes
Mutation
6 Citations (Scopus)

Hb zengcg or α2β2114(g16)leu → met

Plaseska, D., Wilson, J. B., Gu, L. H., Kutlar, F., Huisman, T. H. J., Zeng, Y. T. & Shen, M., Jan 1 1990, In : Hemoglobin. 14, 5, p. 555-557 3 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Abnormal Hemoglobins
Heterozygote
Amino Acid Sequence
Newborn Infant
9 Citations (Scopus)

Hemoglobin Birmingham and hemoglobin Galicia: Two unstable β chain variants characterized by small deletions and insertions

Wilson, J. B., Webber, B. B., Hu, H., Kutlar, A., Kutlar, F., Codrington, J. F., Prchal, J. T., Hall, K. M., De Pablos, J. M., Rodriguez, I. & Huisman, T. H. J., Jan 1 1990, In : Blood. 75, 9, p. 1883-1887 5 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Glutamine
Codon
Leucine
Hemoglobins
68 Citations (Scopus)

Molecular characterization of β‐thalassaemia in 174 Greek patients with thalassaemia major

Kattamis, C., Hu, H., Cheng, G., Reese, A. L., Gonzalez‐Redondo, J. M., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Mar 1990, In : British Journal of Haematology. 74, 3, p. 342-346 5 p.

Research output: Contribution to journalArticle

Thalassemia
beta-Thalassemia
Mutation
Oligonucleotide Probes
Chromosome Mapping
9 Citations (Scopus)

Myristic acid is incorporates into the two acylatable domains of the functional glycoprotein CD9 in ester, but not in amide bonds

Seehafer, J. G., Slupsky, J. R., Tang, S. C., Masellis-Smith, A. & Shaw, A. R. E., Jun 19 1990, In : Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 1039, 2, p. 218-226 9 p.

Research output: Contribution to journalArticle

Myristic Acid
Amides
Glycoproteins
Esters
Fatty Acids
51 Citations (Scopus)

Observations on the levels of Hb A2 in patients with different β-thalassemia mutations and a δ chain variant

Codrington, J. F., Li, H. W., Kutlar, F., Gu, L. H., Ramachandran, M. & Huisman, T. H. J., Jan 1 1990, In : Blood. 76, 6, p. 1246-1249 4 p.

Research output: Contribution to journalArticle

Thalassemia
Globins
Genes
Mutation
Heterozygote
25 Citations (Scopus)
Escherichia coli
Proteins
Amino Acyl-tRNA Synthetases
Transfer RNA
Plasmids
544 Citations (Scopus)

Role of oxidatively modified LDL in atherosclerosis

Steinbrecher, U. P., Zhang, H. & Lougheed, M., Jan 1 1990, In : Free Radical Biology and Medicine. 9, 2, p. 155-168 14 p.

Research output: Contribution to journalArticle

Atherosclerosis
Oxidation
Apolipoproteins B
Macrophages
Phosphatidylcholines
6 Citations (Scopus)

The detection of hemoglobin variants by isoelectrofocusing using EDTA-collected and filter paper-dried cord blood specimens

Kutlar, A., Ozcan, O., Brisco, J. T., Ansley, M. C. & Huisman, T. H. J., Jan 1 1990, In : American Journal of Clinical Pathology. 94, 2, p. 199-202 4 p.

Research output: Contribution to journalArticle

Fetal Blood
Edetic Acid
Hemoglobins
Abnormal Hemoglobins
Hemoglobinopathies
6 Citations (Scopus)

Variation in the level of fetal hemoglobin in (δβ)°‐thalassemia heterozygotes with different numbers of α‐globin genes

Öner, C., Gurgey, A., Altay, C., Kutlar, F. & Huisman, T. H. J., Jan 1 1990, In : American Journal of Hematology. 34, 3, p. 230-231 2 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Thalassemia
Globins
Heterozygote
Fathers
1 Citation (Scopus)

αthalassemia DUE toframeshifts at codons 5, 6, 8, and 8/9; hematological observations in heterozygotes

Aga-Fal, S., Oner, R., Kutlar, F. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 4, p. 471-475 5 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Globins
29 Citations (Scopus)

βthalassemia in Bulgaria

Petkov, G. H., Efremov, G. D., Efremov, D. G., Dimovski, A., Tchaicarova, P., Tchaicarov, R., Rogina, B., Agarwal, S., Kutlar, A., Kutlar, F., Reese, A. L., Stoning, T. A. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

Bulgaria
Thalassemia
Mutation
Oligonucleotide Probes
DNA
75 Citations (Scopus)

βthalassemia in Turkey

Öner, R., Altay, C., Gurgey, A., Aksoy, M., Kilinc, Y., Stoming, T. A., Reese, A. L., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Jan 1 1990, In : Hemoglobin. 14, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Abnormal Hemoglobins
RNA Splice Sites
Thalassemia
Chromosomes
Turkey
1991
10 Citations (Scopus)

Action of bradykinin at the cyclooxygenase step in prostanoid synthesis through the arachidonic acid cascade

Zhang, H., Gaginella, T. S., Chen, X. & Cornwell, D. G., Nov 1 1991, In : Agents and Actions. 34, 3-4, p. 397-404 8 p.

Research output: Contribution to journalArticle

Bradykinin
Prostaglandin-Endoperoxide Synthases
Arachidonic Acid
Prostaglandins
Metabolites
9 Citations (Scopus)

Biochemical modulation of combined radiation and 5-fluorouracil treatment of murine tumors by d,l-leucovorin

Kovacs, C. J., Dainer, P. M., Evans, M. J. & Nyce, J., Jan 1 1991, In : Anticancer research. 11, 2, p. 905-909 5 p.

Research output: Contribution to journalArticle

Leucovorin
Fluorouracil
Radiation
Neoplasms
Therapeutics
28 Citations (Scopus)

Certain mutations observed in the 5’ sequences of theGγ-andAγ-globin genes of βSchromosomes are specific for chromosomes with major haplotypes

Dimovski, A. J., öner, C., Agarwal, S., Gu, Y. C., Gu, L. H., Kutlar, F., Lanclos, K. D. & Huisman, T. H. J., Jan 1 1991, In : Acta Haematologica. 85, 2, p. 79-87 9 p.

Research output: Contribution to journalArticle

Globins
Haplotypes
Chromosomes
Mutation
Genes
12 Citations (Scopus)

Compound heterozygosity for a β{ring operator}-thalassemia (frameshift codons 38/39; -C) and a nondeletional swiss type of HPFH (A→C at NT -110, Gγ) in a Czechoslovakian family

Indrak, K., Indrakova, J., Kutlar, F., Pospisilova, D., Sulovska, I., Baysal, E. & Huisman, T. H. J., Jan 1 1991, In : Annals of Hematology. 63, 2, p. 111-115 5 p.

Research output: Contribution to journalArticle

Thalassemia
Heterozygote
Codon
Fetal Hemoglobin
High Pressure Liquid Chromatography
9 Citations (Scopus)

HB Cleveland or α2β293(f9)CYS→ARG;121(GH4)GLU→GLN

Wilson, J. B., Ramachandran, M., Webber, B. B., Kutlar, F., Hazelnood, L. F., Barnett, D., Hirschler, N. V. & Huisman, T. H. J., Jan 1 1991, In : Hemoglobin. 15, 4, p. 269-278 10 p.

Research output: Contribution to journalArticle

Heme
Substitution reactions
Amino Acid Substitution
Oxygen
Amino Acids
41 Citations (Scopus)

Hemoglobinopathies among the gond tribal groups of central India; interaction of α and βthalassemia with β chain variants

Gupta, R. B., Tiwary, R. S., Pande, P. L., Kutlar, F., Öner, C., Öner, R. & Huisman, T. H. J., Jan 1 1991, In : Hemoglobin. 15, 5, p. 441-458 18 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Molecular Sequence Data
Abnormal Hemoglobins
Hemoglobinopathies
Thalassemia
1 Citation (Scopus)

Heterogeneity of γ-globin chain synthesis in Saudi newborns

Niazi, G. A., Yaish, H. M., Kutlar, F. & Huisman, T. H. J., Jan 1 1991, In : International Journal of Hematology. 54, 5, p. 377-383 7 p.

Research output: Contribution to journalArticle

Globins
Fetal Hemoglobin
Gene Order
Saudi Arabia
Multigene Family
38 Citations (Scopus)

Molecular characterization of Hb S(C) β‐thalassemia in American blacks

Gonzalez‐Redondo, J. M., Kutlar, A., Kutlar, F., McKie, V. C., McKie, K. M., Baysal, E. & Huisman, T. H. J., Sep 1991, In : American Journal of Hematology. 38, 1, p. 9-14 6 p.

Research output: Contribution to journalArticle

Thalassemia
Mutation
Globins
Chromosomes
Southeastern United States