Hematology and Oncology

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1996

Human JC virus nuclear factor 1 binding motifs and large tumor antigen region required for transactivation of late promoter

Kumar, K. U., Devireddy, L. R., Tang, S. C., Pater, A. & Pater, M. M., Aug 1 1996, In : Journal of Neurochemistry. 67, 2, p. 473-481 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Influence of interleukin-2 regimens on circulating populations of lymphocytes after adoptive transfer of anti-CD3-stimulated T cells: Results from a phase I trial in cancer patients

Curti, B. D., Ochoa, A. C., Urba, W. J., Gregory Alvord, W., Kopp, W. C., Powers, G., Hawk, C., Creekmore, S. P., Gause, B. L., Janik, J. E., Holmlund, J. T., Kremers, P., Fenton, R. G., Miller, L., Sznol, M., Smith, J. W., Sharfman, W. H. & Longo, D. L., Jan 1 1996, In : Journal of Immunotherapy with Emphasis on Tumor Immunology. 19, 4, p. 296-308 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Phase II trial of interleukin 1α and indomethacin in treatment of metastatic melanoma

Janik, J. E., Miller, L. L., Longo, D. L., Powers, G. C., Urba, W. J., Kopp, W. C., Gause, B. L., Curti, B. D., Fenton, R. G., Oppenheim, J. J., Conlon, K. C., Holmlund, J. T., Sznol, M., Sharfman, W. H., Steis, R. G., Creekmore, S. P., Alvord, W. G., Beauchamp, A. E. & Smith, J. W., Jan 12 1996, In : Journal of the National Cancer Institute. 88, 1, p. 44-49 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Phase I study of subcutaneously administered interleukin-2 in combination with interferon alfa-2a in patients with advanced cancer

Gause, B. L., Sznol, M., Kopp, W. C., Janik, J. E., Smith, II. W., Steis, R. G., Urba, W. J., Sharfman, W., Fenton, R. G., Creekmore, S. P., Holmlund, J., Conlon, K. C., VanderMolen, L. A. & Longo, D. L., Jan 1 1996, In : Journal of Clinical Oncology. 14, 8, p. 2234-2241 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene

Benlian, P., De Gennes, J. L., Foubert, L., Zhang, H., Gagné, S. E. & Hayden, M., Sep 19 1996, In : New England Journal of Medicine. 335, 12, p. 848-854 7 p.

Research output: Contribution to journalArticle

251 Scopus citations

Reinstituting warfarin in patients who develop warfarin skin necrosis

Jillella, A. & Lutcher, C. L., Jun 1 1996, In : American Journal of Hematology. 52, 2, p. 117-119 3 p.

Research output: Contribution to journalArticle

36 Scopus citations

Up-regulation of hormone response of human papillomavirus type 16 expression and increased DNA-protein binding by consensus mutations of viral glucocorticoid response elements

Khare, S., Kumar, K. U., Tang, S. C., Pater, M. M. & Pater, A., Nov 1 1996, In : Journal of Medical Virology. 50, 3, p. 254-262 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
1995

A lipoprotein lipase mutation (Asn291Ser) is associated with reduced HDL cholesterol levels in premature atherosclerosis

Reymer, P. W. A., Gagné, E., Groenemeyer, B. E., Zhang, H., Forsyth, I., Jansen, H., Seidell, J. C., Kromhout, D., Lie, K. E., Kastelein, J. & Hayden, M. R., Jan 1 1995, In : Nature Genetics. 10, 1, p. 28-34 7 p.

Research output: Contribution to journalArticle

221 Scopus citations

A newly discovered βdeg;thalassemia (IVS-11-850, g→a) mutation in a north european family

Çudie;rük, M. A., Howard, S. C., Kutlar, A. & Huisman, T. H. J., Jan 1 1995, In : Hemoglobin. 19, 3-4, p. 207-211 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cells

Thornton, D. E., Jones, K. H., Jiang, Z., Zhang, H., Liu, G. & Cornwell, D. G., Jan 1 1995, In : Free Radical Biology and Medicine. 18, 6, p. 963-976 14 p.

Research output: Contribution to journalArticle

48 Scopus citations

Clinical course and outcome of patients with hodgkin's disease who progress after autologous transplantation

Varterasian, M., Ratanatharathorn, V., Uberti, J. P., Karanes, C., Abella, E., Momin, F., Kasten-Sportes, C., Al-Katib, A., Lum, L., Heilbrun, L. K. & Sensenbrenner, L. L., Jan 1 1995, In : Leukemia and Lymphoma. 20, 1-2, p. 59-65 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

International Hemoglobin Information Center Variant List

Carver, M. F. & Kutlar, A., Jan 1 1995, In : Hemoglobin. 19, 1-2, p. 37-149 113 p.

Research output: Contribution to journalArticle

7 Scopus citations

Myositis associated with interleukin‐2 therapy in a patient with metastatic renal cell carcinoma

Esteva‐Lorenzo, F. J., Janik, J. E., Fenton, R. G., Emslie‐Smith, A., Engel, A. G. & Longo, D. L., Jan 1 1995, In : Cancer. 76, 7, p. 1219-1223 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Patients with ApoE3 deficiency (E2/2, E3/2, and E4/2) who manifest with hyperlipidemia have increased frequency of an Asn 291→Ser mutation in the human LPL gene

Zhang, H., Reymer, P. W. A., Liu, M. S., Forsythe, I. J., Groenemeyer, B. E., Frohlich, J., Brunzell, J. D., Kastelein, J. J. P., Hayden, M. R. & Ma, Y., Jan 1 1995, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 15, 10, p. 1695-1703 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Phase I/II trial of 5-fluorouracil, leucovorin, zidovudine and dipyridamole for patients with metastatic colorectal cancer, renal cell carcinoma and malignant melanoma

Sharfman, W. H., Urba, W. J., Smith, J. W., Janik, J. E., Curti, B. D., Gause, B. L., Holmlund, J. T., Steis, R. G., Beauchamp, A. E. & Longo, D. L., Jan 1 1995, In : International Journal of Oncology. 6, 3, p. 579-583 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Radioimmunotherapy of interleukin-2Rα-expressing adult T-cell leukemia with Yttrium-90-labeled anti-Tac

Waldmann, T. A., White, J. D., Carrasquillo, J. A., Reynolds, J. C., Paik, C. H., Gansow, O. A., Brechbiel, M. W., Jaffe, E. S., Fleisher, T. A., Goldman, C. K., Top, L. E., Bamford, R., Zaknoen, S., Roessler, E., Sportes, C., England, R., Litou, H., Johnson, J. A. & Jackson-White, T., Jan 1 1995, In : Blood. 86, 11, p. 4063-4075 13 p.

Research output: Contribution to journalArticle

206 Scopus citations

Structural features in lipoprotein lipase necessary for the mediation of lipoprotein uptake into cells

Krapp, A., Zhang, H., Ginzinger, D., Liu, M. S., Lindberg, A., Olivecrona, G., Hayden, M. R. & Beisiegel, U., Jan 1 1995, In : Journal of Lipid Research. 36, 11, p. 2362-2373 12 p.

Research output: Contribution to journalArticle

46 Scopus citations
1994

Alpha thalassemia and stroke risk in sickle cell anemia

Adams, R. J., Kutlar, A., McKie, V., Carl, E., Nichols, F. T., Liu, J. C., McKie, K. & Clary, A., Jan 1 1994, In : American Journal of Hematology. 45, 4, p. 279-282 4 p.

Research output: Contribution to journalArticle

97 Scopus citations

Alteration of lipid profiles in plasma of transgenic mice expressing human lipoprotein lipase

Liu, M. S., Jirik, F. R., LeBoeuf, R. C., Henderson, H., Castellani, L. W., Lusis, A. J., Ma, Y., Forsythe, I. J., Zhang, H., Kirk, E., Brunzell, J. D. & Hayden, M. R., Apr 15 1994, In : Journal of Biological Chemistry. 269, 15, p. 11417-11424 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Analysis of DNA changes in the LPL gene in patients with familial combined hyperlipidemia

Gagné, E., Genest, J., Zhang, H., Clarke, L. A. & Hayden, M. R., Jan 1 1994, In : Arteriosclerosis, thrombosis, and vascular biology. 14, 8, p. 1250-1257 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Clinical significance of bcl-2-MBR gene rearrangement and protein expression in diffuse large-cell non-Hodgkin's lymphoma: An analysis of 83 cases

Tang, S. C., Visser, L., Hepperle, B., Hanson, J. & Poppema, S., Jan 1994, In : Journal of Clinical Oncology. 12, 1, p. 149-154 6 p.

Research output: Contribution to journalArticle

105 Scopus citations

High frequency of mutations in the human lipoprotein lipase gene in pregnancy-induced chylomicronemia: Possible association with apolipoprotein E2 isoform

Ma, Y., Ooi, T. C., Liu, M. S., Zhang, H., McPherson, R., Edwards, A. L., Forsythe, I. J., Frohlich, J., Brunzell, J. D. & Hayden, M. R., Jan 1 1994, In : Journal of Lipid Research. 35, 6, p. 1066-1075 10 p.

Research output: Contribution to journalArticle

89 Scopus citations

Humanized antibody directed to the IL-2 receptor β-chain prolongs primate cardiac allograft survival

Tinubu, S. A., Hakimi, J., Kondas, J. A., Bailon, P., Familletti, P. C., Spence, C., Crittenden, M. D., Parenteau, G. L., Dirbas, F. M., Tsudo, M., Bacher, J. D., Sportes, C., Martinucci, J. L., Goldman, C. K., Clark, R. E. & Waldmann, T. A., Nov 1 1994, In : Journal of Immunology. 153, 9, p. 4330-4338 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Murine α-l-Iduronidase: cDNA isolation and expression

Clarke, L. A., Nasir, J., Zhang, H., McDonald, H., Applegarth, D. A., Hayden, M. R. & Toone, J., Nov 15 1994, In : Genomics. 24, 2, p. 311-316 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Mutagenesis in four candidate heparin binding regions (residues 279-282, 291-304, 390-393, and 439-448) and identification of residues affecting heparin binding of human lipoprotein lipase

Ma, Y., Henderson, H. E., Liu, M. S., Zhang, H., Forsythe, I. J., Clarke-Lewis, I., Hayden, M. R. & Brunzell, J. D., Jan 1 1994, In : Journal of Lipid Research. 35, 11, p. 2049-2059 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Necrotizing pneumonia due to rhodococcus equi in a patient with AIDS

Jillella, A. P., Newman, C. L., Mallory, R. L., Lowman, L. S., Hernandez, L. S. & Fisher, J. F., Jan 1 1994, In : Infectious Diseases in Clinical Practice. 3, 2, p. 117-119 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

T-cell receptor gene rearrangement in T-cell large granular leukocyte leukemia: Preferential Vα but diverse Jα usage in one of five patients

Sportes, C., Zaknoen, S., Steis, R. G., Chan, W. C., Winton, E. F. & Waldmann, T. A., Feb 1 1994, In : Blood. 83, 3, p. 767-775 9 p.

Research output: Contribution to journalArticle

27 Scopus citations
1993

Dose-related immunologic effects of levamisole in patients with cancer

Janik, J. E., Kopp, W. C., Smith, J. W., Longo, D. L., Alvord, W. G., Sharfman, W. H., Fenton, R. G., Sznol, M., Steis, R. G., Creekmore, S. P., Ewel, C. H., Hursey, J. & Urba, W. J., Jan 1 1993, In : Journal of Clinical Oncology. 11, 1, p. 125-135 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Erythropoietin production. A potential marker for interleukin‐2/interferon‐responsive tumors

Janik, J. E., Sharfman, W. H., Smitht, J. W., Longo, D. L., Sznol, M., Urba, W. J., Figlin, R., Pierce, W. C., Bukowski, R. M., Fyfe, G. & Belldegrun, A., Nov 1 1993, In : Cancer. 72, 9, p. 2656-2659 4 p.

Research output: Contribution to journalArticle

31 Scopus citations

Hb adana or α259(E8)Gly→Aspβ2, A severely unstable α1‐globin variant, observed in combination with the ‐(α)20.5 KB α‐thal‐1 deletion in two Turkish patients

Çürük, M. A., Dimovski, A. J., Baysal, E., Gu, L. H., Kutlar, F., Molchanova, T. P., Webber, B. B., Altay, Gürgey, A. & Huisman, T. H. J., Jan 1 1993, In : American Journal of Hematology. 44, 4, p. 270-275 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

High-dose carboplatin and recombinant granulocyte-macrophage colony-stimulating factor in advanced-stage recurrent ovarian cancer

Reed, E., Janik, J. E., Bookman, M. A., Rothenberg, M., Smith, J., Young, R. C., Ozols, R. F., Vandermolen, L., Kohn, E., Jacob, J. L. & Cornelison, T. L., Jan 1 1993, In : Journal of Clinical Oncology. 11, 11, p. 2118-2126 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Interactions between the monocyte/macrophage and the vascular smooth muscle cell: Stimulation of mitogenesis by a soluble factor and of prostanoid synthesis by cell-cell contact

Zhang, H., Downs, E. C., Lindsey, J. A., Davis, W. B., Whisler, R. L. & Cornwall, D. G., Jan 1 1993, In : Arteriosclerosis, thrombosis, and vascular biology. 13, 2, p. 220-230 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Interstitial Pressure of Subcutaneous Nodules in Melanoma and Lymphoma Patients: Changes during Treatment1

Curti, B. D., Janik, J. E., Smith, J. W. & Janik, J. E., Jan 1 1993, In : Cancer Research. 53, 10, p. 2204-2207 4 p.

Research output: Contribution to journalArticle

135 Scopus citations

Levamisole‐Induced Neopterin Synthesis

Janik, J. E., KOPP, WILLIAM. C., II, JOHN. W. SMITH., LONGO, DAN. L., ALVORD, W. GREGORY. & URBA, WALTER. J., Jan 1 1993, In : Annals of the New York Academy of Sciences. 685, 1, p. 252-258 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
10 Scopus citations

Reductive methylation of proteins and lipoproteins causes increased chromogenicity in the lowry assay

Zhang, H. & Steinbrecher, U. P., Jan 1 1993, In : Clinical Chemistry and Enzymology Communications. 5, 3, p. 163-168 6 p.

Research output: Contribution to journalArticle

Spleen in sickle cell anemia: Comparative studies of Nigerian and U.S. patients

Adekile, A. D., McKie, K. M., Adeodu, O. O., Sulzer, A. J., Liu, J. S., McKie, V. C., Kutlar, F., Ramachandran, M., Kaine, W., Akenzua, G. I., Okolo, A. A., Asindi, A. A., Obinyan, E. A., Ogala, W. N., Ibrahim, M. & Huisman, T. H. J., Mar 1993, In : American Journal of Hematology. 42, 3, p. 316-321 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Structural requirements for the binding of modified proteins to the scavenger receptor of macrophages

Zhang, H., Yang, Y. & Steinbrecher, U. P., Mar 15 1993, In : Journal of Biological Chemistry. 268, 8, p. 5535-5542 8 p.

Research output: Contribution to journalArticle

98 Scopus citations

The Effects of Treatment with Interleukin-1α on Platelet Recovery after High-Dose Carboplatin

Smith, J. W., Longo, D. L., Alvord, W. G., Janik, J. E., Sharfman, W. H., Gause, B. L., Curti, B. D., Creekmore, S. P., Holmlund, J. T., Fenton, R. G., Sznol, M., Miller, L. L., Shimizu, M., Oppenheim, J. J., Fiem, S. J., Hursey, J. C., Powers, G. C. & Urba, W. J., Mar 18 1993, In : New England Journal of Medicine. 328, 11, p. 756-761 6 p.

Research output: Contribution to journalArticle

111 Scopus citations

Treatment of cancer patients with ex vivo anti-CD3-activated killer cells and interleukin-2

Curti, B. D., Longo, D. L., Ochoa, A. C., Conlon, K. C., Smith, J. W., Alvord, W. G., Creekmore, S. P., Fenton, R. G., Gause, B. L., Holmlund, J., Janik, J. E., Ochoa, J., Rice, P. A., Sharfman, W. H., Sznol, M. & Urba, W. J., Jan 1 1993, In : Journal of Clinical Oncology. 11, 4, p. 652-660 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Usefulness of HPLC methodology for the characterization of combinations of the common β chain variants HBS s, c, and o-ARAB, and the α chain variant HB g-philadelphia

Kutlar, F., Kutlar, A., Nuguid, E., Prchal, J. & Huisman, T. H. J., Jan 1 1993, In : Hemoglobin. 17, 1, p. 55-66 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

βthalassehia mutations in the portuguese; high frequencies of two alleles in restricted populations

Tamagnini, G. P., Gonçalves, P., Ribeiro, M. L. S., Kaeda, J., Kutlar, F., Baysal, E. & Huisman, T. H. J., Jan 1 1993, In : Hemoglobin. 17, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
1992

A NOVEL β°‐THALASSAEMIA MUTATION (CODON 15, TGG→TGA) IS PREVALENT IN A POPULATION OF CENTRAL PORTUGAL

Ribeiro, M. L. S., Baysal, E., Kutlar, F., Tamagnini, G. P., Goncalves, P., Lopes, D. & Huisman, T. H. J., Apr 1992, In : British Journal of Haematology. 80, 4, p. 567-568 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Anti-CD3 Monoclonal Antibody Treatment of Patients with CD3-Negative Tumors: A Phase IA/B Study

Urba, W. J., Ewel, C., Kopp, W., Rossio, J., Beveridge, J., Fenton, R., Janik, J., Longo, D. L. & Janik, J. E., Jan 1 1992, In : Cancer Research. 52, 9, p. 2394-2401 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Black β‐thalassemia homozygotes with specific sequence variations in the 5′ hypersensitive site‐2 of the locus control region have high levels of fetal hemoglobin

Beris, P., Kitundu, M. N., Baysal, E., Öner, C., Lanclos, K. D., Dimovski, A. J., Kutlar, F. & Huisman, T. H. J., Oct 1992, In : American Journal of Hematology. 41, 2, p. 97-101 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

HB shelby [α2β2131(h9)GLN→LYS]-βdeg;thalassemia [codon 15 (TGG→TGA)] identified by DNA sequencing

Cürük, M. A., Kutlar, A. & Huisman, T. H. J., Jan 1 1992, In : Hemoglobin. 16, 5, p. 417-419 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Intensive therapy with cisplatin, interleukin-2 and interferon-alpha-2a in patients with metastatic melanoma. A phase II Study.

Sznol, M., Steis, R. G., Smith, J. W., Janik, J. E., Sharfman, W. H., Urba, W. J., Fenton, R. G., Creekmore, S. P., Beveridge, J. & Longo, D. L., Jul 1 1992, In : The Online journal of current clinical trials [electronic resource]. Doc No 9

Research output: Contribution to journalArticle

3 Scopus citations

Molecular characterization of β-thalassemia in Czechoslovakia

Indrak, K., Brabec, V., Indrakova, J., Chrobak, L., Sakalova, A., Jarosova, M., Cermak, J., Fei, Y. J., Kutlar, F., Gu, Y. C., Baysal, E. & Huisman, T. H. J., Jan 1 1992, In : Human Genetics. 88, 4, p. 399-404 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Pilot study of interleukin-2 and lymphokine-activated killer cells combined with immunomodulatory doses of chemotherapy and sequenced with interferon alfa-2a in patients with metastatic melanoma and renal cell carcinoma

Sznol, M., Clark, J. W., Smith, J. W., Steis, R. G., Urba, W. J., Rubinstein, L. V., Vandermolen, L. A., Janik, J. E., Sharfman, W. H., Fenton, R. G., Creekmore, S. P., Kremers, P., Conlon, K., Hersey, J., Beveridge, J. & Longo, D. L., Jun 17 1992, In : Journal of the National Cancer Institute. 84, 12, p. 929-937 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Protocol for the study of the metabolism of retinyl esters in plasma lipoproteins during postprandial lipemia

Ruotolo, G., Zhang, H., Bentsianov, V. & Le, N. A., Jan 1 1992, In : Journal of Lipid Research. 33, 10, p. 1541-1549 9 p.

Research output: Contribution to journalArticle

69 Scopus citations