Hematology and Oncology

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2011

Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms

Dos Santos, J. L., Lanaro, C., Lima, L. M., Gambero, S., Franco-Penteado, C. F., Alexandre-Moreira, M. S., Wade, M., Yerigenahally, S., Kutlar, A., Meiler, S. E., Costa, F. F. & Chung, M., Aug 25 2011, In : Journal of Medicinal Chemistry. 54, 16, p. 5811-5819 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Disseminated Strongyloides stercoralis infection in HTLV-1-associated adult T-cell leukemia/lymphoma

Stewart, D. M., Ramanathan, R., Mahanty, S., Fedorko, D. P., Janik, J. E. & Morris, J. C., Aug 1 2011, In : Acta Haematologica. 126, 2, p. 63-67 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

eNOS activation and NO function: Structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity

Rafikov, R., Fonseca, F. V., Kumar, S., Pardo, D., Darragh, C., Elms, S., Fulton, D. & Black, S. M., Sep 1 2011, In : Journal of Endocrinology. 210, 3, p. 271-284 14 p.

Research output: Contribution to journalArticle

130 Scopus citations

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

Elliott, N. E., Cleveland, S. M., Grann, V., Janik, J., Waldmann, T. A. & Davé, U. P., Oct 6 2011, In : Blood. 118, 14, p. 3911-3921 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

Flow cytometric immunophenotypic assessment of T-cell clonality by V β repertoire analysis: Detection of T-cell clonality at diagnosis and monitoring of minimal residual disease following therapy

Tembhare, P., Yuan, C. M., Xi, L., Morris, J. C., Liewehr, D., Venzon, D., Janik, J. E., Raffeld, M. & Stetler-Stevenson, M., Jun 1 2011, In : American Journal of Clinical Pathology. 135, 6, p. 890-900 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Genetic association for renal traits among participants of African Ancestry reveals new loci for renal function

Liu, C. T., Garnaas, M. K., Tin, A., Kottgen, A., Franceschini, N., Peralta, C. A., de Boer, I. H., Lu, X., Atkinson, E., Ding, J., Nalls, M., Shriner, D., Coresh, J., Kutlar, A., Bibbins-Domingo, K., Siscovick, D., Akylbekova, E., Wyatt, S., Astor, B., Mychaleckjy, J. & 21 others, Li, M., Reilly, M. P., Townsend, R. R., Adeyemo, A., Zonderman, A. B., de Andrade, M., Turner, S. T., Mosley, T. H., Harris, T. B., Rotimi, C. N., Liu, Y., Kardia, S. L. R., Evans, M. K., Shlipak, M. G., Kramer, H., Flessner, M. F., Dreisbach, A. W., Goessling, W., Cupples, L. A., Kao, W. L. & Fox, C. S., Sep 1 2011, In : PLoS Genetics. 7, 9, e1002264.

Research output: Contribution to journalArticle

80 Scopus citations

Hydroxycarbamide in very young children with sickle-cell anaemia: A multicentre, randomised, controlled trial (BABY HUG)

Wang, W. C., Ware, R. E., Miller, S. T., Iyer, R. V., Casella, J. F., Minniti, C. P., Rana, S., Thornburg, C. D., Rogers, Z. R., Kalpatthi, R. V., Barredo, J. C., Brown, R. C., Sarnaik, S. A., Howard, T. H., Wynn, L. W., Kutlar, A., Armstrong, F. D., Files, B. A., Goldsmith, J. C., Waclawiw, M. A. & 2 others, Huang, X. & Thompson, B. W., May 14 2011, In : The Lancet. 377, 9778, p. 1663-1672 10 p.

Research output: Contribution to journalArticle

396 Scopus citations

Improvements in haemolysis and indicators of erythrocyte survival do not correlate with acute vaso-occlusive crises in patients with sickle cell disease: A phase III randomized, placebo-controlled, double-blind study of the gardos channel blocker senicapoc (ICA-17043)

Ataga, K. I., Reid, M., Ballas, S. K., Yasin, Z., Bigelow, C., James, L. S., Smith, W. R., Galacteros, F., Kutlar, A., Hull, J. H. & Stocker, J. W., Apr 1 2011, In : British Journal of Haematology. 153, 1, p. 92-104 13 p.

Research output: Contribution to journalArticle

113 Scopus citations

Long-term safety and efficacy of deferasirox (Exjade®) for up to 5years in transfusional iron-overloaded patients with sickle cell disease

Vichinsky, E., Bernaudin, F., Forni, G. L., Gardner, R., Hassell, K., Heeney, M. M., Inusa, B., Kutlar, A., Lane, P., Mathias, L., Porter, J., Tebbi, C., Wilson, F., Griffel, L., Deng, W., Giannone, V. & Coates, T., Aug 1 2011, In : British Journal of Haematology. 154, 3, p. 387-397 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

P2Y receptors as regulators of lung endothelial barrier integrity

Zemskov, E., Lucas, R., Verin, A. D. & Umapathy, N. S., Jan 1 2011, In : Journal of Cardiovascular Disease Research. 2, 1, p. 14-22 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Phase i trial of 7-hydroxystaurosporine and fludararbine phosphate: In vivo evidence of 7-hydroxystaurosporine induced apoptosis in chronic lymphocytic leukemia

Marti, G. E., Stetler-Stevenson, M., Grant, N. D., White, T., Figg, W. D., Tohnya, T., Jaffe, E. S., Dunleavy, K., Janik, J. E., Steinberg, S. M. & Wilson, W. H., Dec 1 2011, In : Leukemia and Lymphoma. 52, 12, p. 2284-2292 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Phase I trial of adoptive cell transfer with mixed-profile type-I/type-II allogeneic T cells for metastatic breast cancer

Hardy, N. M., Mossoba, M. E., Steinberg, S. M., Fellowes, V., Yan, X. Y., Hakim, F. T., Babb, R. R., Avila, D., Gea-Banacloche, J., Sportés, C., Levine, B. L., June, C. H., Khuu, H. M., Carpenter, A. E., Krumlauf, M. C., Dwyer, A. J., Gress, R. E., Fowler, D. H. & Bishop, M. R., Nov 1 2011, In : Clinical Cancer Research. 17, 21, p. 6878-6887 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

Meiler, S. E., Wade, M., Kutlar, F., Yerigenahally, S. D., Xue, Y., Moutouh-de Parseval, L. A., Corral, L. G., Swerdlow, P. S. & Kutlar, A., Jul 28 2011, In : Blood. 118, 4, p. 1109-1112 4 p.

Research output: Contribution to journalArticle

44 Scopus citations
27 Scopus citations

Purification and functional analysis of protein kinase G-1α using a bacterial expression system

Aggarwal, S., Rafikov, R., Gross, C. M., Kumar, S., Pardo, D. & Black, S. M., Oct 1 2011, In : Protein Expression and Purification. 79, 2, p. 271-276 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Thalassemia-like phenotype in a novel complex hemoglobinopathy with α, β, δ globin chain abnormalities

Sabio, H., Dixon, N., Patel, N., Obiaga, C., Zhuang, L., Meiler, S. E., Kutlar, A. & Kutlar, F., Dec 1 2011, In : Journal of Pediatric Hematology/Oncology. 33, 8, p. 589-591 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

The proinflammatory cytokine GM-CSF downregulates fetal hemoglobin expression by attenuating the cAMP-dependent pathway in sickle cell disease

Ikuta, T., Adekile, A. D., Gutsaeva, D. R., Parkerson, J. B., Yerigenahally, S. D., Clair, B., Kutlar, A., Odo, N. & Head, C. A., Dec 15 2011, In : Blood Cells, Molecules, and Diseases. 47, 4, p. 235-242 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

The risk factors and prognosis of bilateral primary breast cancer: A comparative study with unilateral breast cancer

Wang, T., Liu, H., Chen, K. X., Xun, P., Li, H. X. & Tang, S. C., Mar 14 2011, In : Oncology Research. 19, 3-4, p. 171-178 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cells

Ganapathy, P. S., White, R. E., Ha, Y., Renee Bozard, B., McNeil, P. L., Caldwell, R. W., Kumar, S., Black, S. M. & Smith, S. B., Jul 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 8, p. 5515-5524 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Tumor markers in hairy cell leukemia

Janik, J. E., Jun 1 2011, In : Leukemia and Lymphoma. 52, SUPPL. 2, p. 69-71 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma

Schuster, S. J., Neelapu, S. S., Gause, B. L., Janik, J. E., Muggia, F. M., Gockerman, J. P., Winter, J. N., Flowers, C. R., Nikcevich, D. A., Sotomayor, E. M., McGaughey, D. S., Jaffe, E. S., Chong, E. A., Reynolds, C. W., Berry, D. A., Santos, C. F., Popa, M. A., McCord, A. M. & Kwak, L. W., Jul 10 2011, In : Journal of Clinical Oncology. 29, 20, p. 2787-2794 8 p.

Research output: Contribution to journalArticle

180 Scopus citations
2010

Acute myelogenous leukemia patients are at low risk for invasive fungal infections after high-dose cytarabine consolidations and thus do not require prophylaxis

Lewis, G., Hall, P., Eisa, N., Deremer, D., Dobbins, R., El-Geneidy, M., Jillella, A. & Ustun, C., Dec 1 2010, In : Acta Haematologica. 124, 4, p. 206-213 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

A new sickling variant 'Hb S-Wake β[(Glu6Val-Asn139 Ser)]' found in a compound heterozygote with Hb S β(Glu6Val) coinherited with homozygous α-thalassemia-2: Phenotype and molecular characteristics

Kutlar, F., Redding-Lallinger, R., Meiler, S. E., Bakanay, S. M., Borders, L. & Kutlar, A., Oct 1 2010, In : Acta Haematologica. 124, 2, p. 120-124 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemia

Chen, J., Petrus, M., Bryant, B. R., Nguyen, V. P., Goldman, C. K., Bamford, R., Morris, J. C., Janik, J. E. & Waldmann, T. A., Dec 23 2010, In : Blood. 116, 26, p. 5948-5956 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype

Ding, Z. C., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Mar 25 2010, In : Blood. 115, 12, p. 2397-2406 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Correlation of pretransplant and early post-transplant response assessment with outcomes after reduced-intensity allogeneic hematopoietic stem cell transplantation for non-Hodgkin's lymphoma

Bishop, M. R., Dean, R. M., Steinberg, S. M., Odom, J., Pollack, S. M., Pavletic, S. Z., Sportes, C., Gress, R. E. & Fowler, D. H., Feb 15 2010, In : Cancer. 116, 4, p. 852-862 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

DNA prime-protein boost increased the titer, avidity and persistence of anti-AΒ antibodies in wild-type mice

Davtyan, H., Mkrtichyan, M., Movsesyan, N., Petrushina, I., Mamikonyan, G., Cribbs, D. H., Agadjanyan, M. G. & Ghochikyan, A., Feb 1 2010, In : Gene Therapy. 17, 2, p. 261-271 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

Kochenderfer, J. N., Wilson, W. H., Janik, J. E., Dudley, M. E., Stetler-Stevenson, M., Feldman, S. A., Maric, I., Raffeld, M., Nathan, D. A. N., Lanier, B. J., Morgan, R. A. & Rosenberg, S. A., Nov 18 2010, In : Blood. 116, 20, p. 4099-4102 4 p.

Research output: Contribution to journalArticle

707 Scopus citations

Gene silencing of BAG-1 modulates apoptotic genes and sensitizes lung cancer cell lines to cisplatin-induced apoptosis

Liu, H., Liang, Y., Li, Y., Li, Y., Wang, J., Wu, H., Wang, Y., Tang, S. C., Chen, J. & Zhou, Q., May 15 2010, In : Cancer Biology and Therapy. 9, 10, p. 832-840 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Inhibition of endothelial nitric oxide synthase by the lipid phosphatase PTEN

Church, J. E., Qian, J., Kumar, S., Black, S. M., Venema, R. C., Papapetropoulos, A. & Fulton, D. J. R., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 191-198 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Low concentrations of anti-Aβ antibodies generated in Tg2576 mice by DNA epitope vaccine fused with 3C3d molecular adjuvant do not affect AD pathology

Movsesyan, N., Davtyan, H., Mkrtichyan, M., Petrushina, I., Tiraturyan, T., Ross, T., Agadjanyan, M. G., Ghochikyan, A. & Cribbs, D. H., Nov 1 2010, In : Human Gene Therapy. 21, 11, p. 1569-1576 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: Role of asymmetric dimethylarginine

Sharma, S., Smith, A., Kumar, S., Aggarwal, S., Rehmani, I., Snead, C., Harmon, C., Fineman, J., Fulton, D. J., Catravas, J. D. & Black, S. M., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 182-190 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Minimal residual disease detection by flow cytometry in adult T-cell leukemia/lymphoma

Shao, H., Yuan, C. M., Xi, L., Raffeld, M., Morris, J. C., Janik, J. E. & Stetler-Stevenson, M., Apr 1 2010, In : American Journal of Clinical Pathology. 133, 4, p. 592-601 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Molecular mechanisms involved in adenosine-induced endothelial cell barrier enhancement

Siddaramappa, U. N., Fan, Z. H., Zemskov, E. A., Alieva, I. B., Black, S. M. & Verin, A. D., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 199-206 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia

Vichinsky, E. P., Neumayr, L. D., Gold, J. I., Weiner, M. W., Rule, R. R., Truran, D., Kasten, J., Eggleston, B., Kesler, K., McMahon, L., Orringer, E. P., Harrington, T., Kalinyak, K., De Castro, L. M., Kutlar, A., Rutherford, C. J., Johnson, C., Bessman, J. D., Jordan, L. B. & Armstrong, F. D., May 12 2010, In : JAMA - Journal of the American Medical Association. 303, 18, p. 1823-1831 9 p.

Research output: Contribution to journalArticle

145 Scopus citations

Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow

Sharma, S., Kumar, S., Wiseman, D. A., Kallarackal, S., Ponnala, S., Elgaish, M., Tian, J., Fineman, J. R. & Black, S. M., Jul 1 2010, In : Vascular Pharmacology. 53, 1-2, p. 38-52 15 p.

Research output: Contribution to journalArticle

13 Scopus citations

Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy

Sportès, C., Babb, R. R., Krumlauf, M. C., Hakim, F. T., Steinberg, S. M., Chow, C. K., Brown, M. R., Fleisher, T. A., Noel, P., Maric, I., Stetler-Stevenson, M., Engel, J., Buffet, R., Morre, M., Amato, R. J., Pecora, A., Mackall, C. L. & Gress, R. E., Jan 15 2010, In : Clinical Cancer Research. 16, 2, p. 727-735 9 p.

Research output: Contribution to journalArticle

124 Scopus citations

Plasma interleukin-1β concentration is associated with stroke in sickle cell disease

Asare, K., Gee, B. E., Stiles, J. K., Wilson, N. O., Driss, A., Quarshie, A., Adams, R. J., Kutlar, A. & Hibbert, J. M., Jan 1 2010, In : Cytokine. 49, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Posterior segment ophthalmic complications of aplastic anemia.

Agarwal, M., Yeh, S., Faia, L. J., Bishop, R. J., Lai, M. M., Pantin, J. M., Scheinberg, P., Chew, E. Y. & Weichel, E. D., Jan 1 2010, In : Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye. 41 Online

Research output: Contribution to journalArticle

2 Scopus citations
36 Scopus citations

Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter

Miyauchi, S., Gopal, E., Babu, E., Srinivas, S. R., Kubo, Y., Umapathy, N. S., Thakkar, S. V., Ganapathy, V. & Prasad, P. D., Jun 1 2010, In : Biochimica et Biophysica Acta - Biomembranes. 1798, 6, p. 1164-1171 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - A crucial role for protein kinase C-α inhibition

Xiong, C., Yang, G., Kumar, S., Aggarwal, S., Leustik, M., Snead, C., Hamacher, J., Fischer, B., Siddaramappa, U. N., Hossain, H., Wendel, A., Catravas, J. D., Verin, A. D., Fulton, D. J., Black, S. M., Chakraborty, T. & Lucas, R., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 207-213 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

The lectin-like doMain of tumor necrosis factor improves lung function after rat lung transplantation-Potential role for a reduction in reactive oxygen species generation

Hamacher, J., Stammberger, U., Roux, J., Kumar, S., Yang, G., Xiong, C., Schmid, R. A., Fakin, R. M., Chakraborty, T., Hossain, H. M. D., Pittet, J. F., Wendel, A., Black, S. M. & Lucas, R., Mar 2010, In : Critical care medicine. 38, 3, p. 871-878 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up

Steinberg, M. H., McCarthy, W. F., Castro, O., Ballas, S. K., Armstrong, F. D., Smith, W., Ataga, K., Swerdlow, P., Kutlar, A., DeCastro, L., Waclawiw, M. A., Orringer, E., Jones, S., Strayhorn, D., Rosse, W., Phillips, G., Peace, D., Johnson-Telfair, A., Daitch, L. H., Milner, P. & 91 others, Tracy, A., Valdez, S., Allen, G. E., Moshang, J., Scott, B., Bigelow, C., Anderson, A., Sabahi, V., Harrington, T., Labrousse, W., Pegelow, C., Temple, D., Case, E., Harrell, R., Childerie, S., Embury, S., Schmidt, B., Davies, D., Saunthararajah, Y., Koshy, M., Talischy-Zahed, N., Dorn, L., Pendarvis, G., McGee, M., Telfer, M., Davis, A., Onyekwere, O. C., Nwokolo, C., Finke, H., Perlin, E., Siteman, J., Bryan, M., Saunders, T., Barber, Y., Gascon, P., Di Paolo, P., Gargiulo, S., Eckman, J., Carter-Randall, E., Bailey, J. H., Platt, A., Waller, L., Ramirez, G., Knors, V., Hernandez, S., Rodriguez, E. M., Wilkes, E., Vichinsky, E., Hagar, W., Hoehner, C., Hackney-Stevens, E., Claster, S., Earles, A., Kleman, K., McLaughlin, K., White, L., Maddox, B., Usry, L., Brenner, A., Williams, K., O'Brien, R., Genther, K., Shurin, S., Berman, B., Chiarucci, K., Keverline, L., Olivieri, N., Chow, J., Hui, M., Shaw, D., Lewis, N., Okam, M., Mandell, E., Palmer, A., Bridges, K., Tynan, B., Winograd, C., Bellevue, R., Dosik, H., Sheikhai, M., Ryans, P., Souffrant, H., Adler, B., Johnson-Telfair, A., Eskridge, L., Prchal, J., Braddock, J., McArdle, T., Carlos, T., Roundtree-Schmotzer, A. & Gardner, D., Jun 1 2010, In : American Journal of Hematology. 85, 6, p. 403-408 6 p.

Research output: Contribution to journalArticle

261 Scopus citations

Visual inspection versus quantitative flow cytometry to detect aberrant CD2 expression in malignant T cells

Arun, I., Wulu, J. A., Janik, J. E., Jasper, G. A., Yuan, C. M., Venzon, D. & Stetler-Stevenson, M., May 1 2010, In : Cytometry Part B - Clinical Cytometry. 78, 3, p. 169-175 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2009

Acute splenic complications and implications of splenectomy in hemoglobin SC disease

Subbannan, K., Ustun, C., Natarajan, K., Clair, B., Daitch, L., Fields, S., Kutlar, F. & Kutlar, A., Sep 1 2009, In : European Journal of Haematology. 83, 3, p. 258-260 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Alterations in lung arginine metabolism in lambs with pulmonary hypertension associated with increased pulmonary blood flow

Sharma, S., Kumar, S., Sud, N., Wiseman, D. A., Tian, J., Rehmani, I., Datar, S., Oishi, P., Fratz, S., Venema, R. C., Fineman, J. R. & Black, S. M., Nov 1 2009, In : Vascular Pharmacology. 51, 5-6, p. 359-364 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Compound heterozygosity for hemoglobin S [β6(A3)Glu6Val] and hemoglobin Korle-Bu [β73(E17)Asp73Asn]

Akl, P. S., Kutlar, F., Patel, N., Salisbury, C. L., Lane, P. & Young, A. N., Sep 1 2009, In : Laboratory Hematology. 15, 3, p. 20-24 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Cotreatment with BCL-2 antagonist sensitizes cutaneous T-cell lymphoma to lethal action of HDAC7-Nur77-based mechanism

Chen, J., Fiskus, W., Eaton, K., Fernandez, P., Wang, Y., Rao, R., Lee, P., Joshi, R., Yang, Y., Kolhe, R., Balusu, R., Chappa, P., Natarajan, K., Jillella, A., Atadja, P. & Bhalla, K. N., Nov 17 2009, In : Blood. 113, 17, p. 4038-4048 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells

Wang, Y., Fiskus, W., Chong, D. G., Buckley, K. M., Natrajan, K., Rao, R., Joshi, A., Balusu, R., Koul, S., Chen, J., Savoie, A., Ustun, C., Jillella, A., Atadja, P., Levine, R. L. & Bhalla, K. N., Dec 3 2009, In : Blood. 114, 24, p. 5024-5033 10 p.

Research output: Contribution to journalArticle

121 Scopus citations