Hematology and Oncology

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2008

Plasmablastic lymphoma with small lymphocytic lymphoma: Clinico-pathologic features, and review of the literature

Ramalingam, P., Nayak-Kapoor, A., Reid-Nicholson, M., Jones-Crawford, J. & Ustun, C., Nov 5 2008, In : Leukemia and Lymphoma. 49, 10, p. 1999-2002 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Predictive markers of tubulin-targeting agents in breast cancer

Tang, S-C., Jan 1 2008, In : Clinical Breast Cancer. 8, SUPPL. 2

Research output: Contribution to journalArticle

6 Scopus citations

Progressive dysfunction of nitric oxide synthase in a lamb model of chronically increased pulmonary blood flow: A role for oxidative stress

Oishi, P. E., Wiseman, D. A., Sharma, S., Kumar, S., Hou, Y., Datar, S. A., Azakie, A., Johengen, M. J., Harmon, C., Fratz, S., Fineman, J. R. & Black, S. M., Nov 1 2008, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 295, 5, p. L756-L766

Research output: Contribution to journalArticle

30 Scopus citations

Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - A novel immunotherapeutic strategy

Movsesyan, N., Ghochikyan, A., Mkrtichyan, M., Petrushina, I., Davtyan, H., Olkhanud, P. B., Head, E., Biragyn, A., Cribbs, D. H. & Agadjanyan, M. G., May 7 2008, In : PloS one. 3, 5, e2124.

Research output: Contribution to journalArticle

90 Scopus citations

Targeted deletion of Tssk1 and 2 causes male infertility due to haploinsufficiency

Xu, B., Hao, Z., Jha, K. N., Zhang, Z., Urekar, C., Digilio, L., Pulido, S., Strauss, J. F., Flickinger, C. J. & Herr, J. C., Jul 15 2008, In : Developmental Biology. 319, 2, p. 211-222 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

TSKS concentrates in spermatid centrioles during flagellogenesis

Xu, B., Hao, Z., Jha, K. N., Zhang, Z., Urekar, C., Digilio, L., Pulido, S., Strauss, J. F., Flickinger, C. J. & Herr, J. C., Jul 15 2008, In : Developmental Biology. 319, 2, p. 201-210 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Two new hemoglobin variants: Hb Sinai-Greenspring [β34(B16) Val→Ile, GTC > ATC] and Hb Sinai-Bel Air [β53(D4)Ala→Asp, GCT > GAT]

Dainer, E., Wenk, R. E., Luddy, R., Elam, D., Holley, L., Kutlar, A. & Kutlar, F., Nov 1 2008, In : Hemoglobin. 32, 6, p. 588-591 4 p.

Research output: Contribution to journalArticle

2007

A novel role for Bcl-2 associated-athanogene-1 (Bag-1) in regulation of the endoplasmic reticulum stress response in mammalian chondrocytes

Yang, L., McBurney, D., Tang, S-C., Carlson, S. G. & Horton, W. E., Oct 15 2007, In : Journal of cellular biochemistry. 102, 3, p. 786-800 15 p.

Research output: Contribution to journalArticle

25 Scopus citations

Anti-Aβ1-11 antibody binds to different β-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers

Mamikonyan, G., Necula, M., Mkrtichyan, M., Ghochikyan, A., Petrushina, I., Movsesyan, N., Mina, E., Kiyatkin, A., Glabe, C. G., Cribbs, D. H. & Agadjanyan, M. G., Aug 3 2007, In : Journal of Biological Chemistry. 282, 31, p. 22376-22386 11 p.

Research output: Contribution to journalArticle

85 Scopus citations

A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy

O'Mahony, D., Morris, J. C., Quinn, C., Gao, W., Wilson, W. H., Gause, B., Pittaluga, S., Neelapu, S., Brown, M., Fleisher, T. A., Gulley, J. L., Schlom, J., Nussenblatt, R., Albert, P., Davis, T. A., Lowy, I., Petrus, M., Waldmann, T. A. & Janik, J. E., Feb 1 2007, In : Clinical Cancer Research. 13, 3, p. 958-964 7 p.

Research output: Contribution to journalArticle

137 Scopus citations

Aplastic crisis revealing the diagnosis of Hb Evans [α62(E11) Val→Met, GTG→ATG (α2)] in a Hispanic kindred: Case report and review

Steiner, L. A., Van Hoff, J., Kutlar, F. & Gallagher, P. G., Oct 1 2007, In : Hemoglobin. 31, 4, p. 409-416 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Aurintricarboxylic acid inhibits protein synthesis independent, sanguinarine-induced apoptosis and oncosis

Hallock, S., Tang, S-C., Buja, L. M., Trump, B. F., Liepins, A. & Weerasinghe, P., Mar 12 2007, In : Toxicologic Pathology. 35, 2, p. 300-309 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney

Gopal, E., Umapathy, N. S., Martin, P. M., Ananth, S., Gnana-Prakasam, J. P., Becker, H., Wagner, C. A., Ganapathy, V. & Prasad, P. D., Nov 1 2007, In : Biochimica et Biophysica Acta - Biomembranes. 1768, 11, p. 2690-2697 8 p.

Research output: Contribution to journalArticle

53 Scopus citations
44 Scopus citations

Diagnostic approach to hemoglobinopathies

Kutlar, F., Apr 1 2007, In : Hemoglobin. 31, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Effective therapy of murine models of human leukemia and lymphoma with radiolabeled anti-CD30 antibody, HeFi-1

Zhang, M., Yao, Z., Patel, H., Garmestani, K., Zhang, Z., Talanov, V. S., Plascjak, P. S., Goldman, C. K., Janik, J. E., Brechbiel, M. W. & Waldmann, T. A., May 15 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 20, p. 8444-8448 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Elicitation of T cell responses to histologically unrelated tumors by immunization with the novel cancer-testis antigen, brother of the regulator of imprinted sites

Ghochikyan, A., Mkrtichyan, M., Loukinov, D., Mamikonyan, G., Pack, S. D., Movsesyan, N., Ichim, T. E., Cribbs, D. H., Lobanenkov, V. V. & Agadjanyan, M. G., Jan 1 2007, In : Journal of Immunology. 178, 1, p. 566-573 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Fetal hemoglobin in sickle cell anemia: Genetic determinants of response to hydroxyurea

Ma, Q., Wyszynski, D. F., Farrell, J. J., Kutlar, A., Farrer, L. A., Baldwin, C. T. & Steinberg, M. H., Dec 1 2007, In : Pharmacogenomics Journal. 7, 6, p. 386-394 9 p.

Research output: Contribution to journalArticle

85 Scopus citations

Lung antioxidant enzymes are regulated by development and increased pulmonary blood flow

Sharma, S., Grobe, A. C., Wiseman, D. A., Kumar, S., Englaish, M., Najwer, I., Benavidez, E., Oishi, P., Azakie, A., Fineman, J. R. & Black, S. M., Oct 1 2007, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 293, 4

Research output: Contribution to journalArticle

23 Scopus citations

Missense mutation of the last nucleotide of exon 1 (G->C) of β globin gene not only leads to undetectable mutant peptide and transcript but also interferes with the expression of wild allele

Agarwal, N., Kutlar, F., Mojica-Henshaw, M. P., Ou, C. N., Gaikwad, A., Reading, N. S., Bailey, L., Kutlar, A. & Prchal, J. T., Dec 1 2007, In : Haematologica. 92, 12, p. 1715-1716 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mixed chimerism and graft failure following conditioning with the fludarabine and cyclophosphamide nonablative regimen; conversion to full donor chimerism

Jillella, A. P., Shafer, D., Klumpp, T. R., Emmons, R. V. B. & Mangan, K. F., Jun 1 2007, In : American Journal of Hematology. 82, 6, p. 419-426 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Morbidity and mortality in chronically transfused subjects with Thalassemia and Sickle Cell Disease: A report from the multi-center study of iron overload

Fung, E. B., Harmatz, P., Milet, M., Ballas, S. K., De Castro, L., Hagar, W., Owen, W., Olivieri, N., Smith-Whitley, K., Darbari, D., Wang, W., Vichinsky, E., Balasa, V., Bellevue, R., Cassela, J., Coates, T., Davis, C., Giardina, P., Hilliard, L., Hord, J. & 15 others, Jeng, M., Kirby, M., Kutlar, A., McClain, K., Mentzer, W., Mignaca, R., Pegelow, C., Porter, J., Ramirez, G., Ranalli, M., Rao, S., Scher, C., Shafer, F., Smith, M. G. & Thompson, A., Apr 1 2007, In : American Journal of Hematology. 82, 4, p. 255-265 11 p.

Research output: Contribution to journalArticle

93 Scopus citations

Nitric oxide and superoxide generation from endothelial NOS: Modulation by HSP90

Sud, N., Sharma, S., Wiseman, D. A., Harmon, C., Kumar, S., Venema, R. C., Fineman, J. R. & Black, S. M., Dec 2007, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 293, 6, p. L1444-L1453

Research output: Contribution to journalArticle

64 Scopus citations

Nordihydroguaiaretic acid increases endothelial nitric oxide synthase expression via the transcription factor AP-1

Kumar, S., Wedgwood, S. & Black, S. M., Dec 1 2007, In : DNA and Cell Biology. 26, 12, p. 853-862 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Oral Mucositis-Related Oropharyngeal Pain and Correlative Tumor Necrosis Factor-α Expression in Adult Oncology Patients Undergoing Hematopoietic Stem Cell Transplantation

FalI-Dickson, J. M., Ramsay, E. S., Castro, K., Woltz, P. & Sportés, C., Dec 28 2007, In : Clinical Therapeutics. 29, 11 SUPPL. 1, p. 2547-2561 15 p.

Research output: Contribution to journalArticle

22 Scopus citations

Pediatric pulmonary hypertension: Roles of endothelin-1 and nitric oxide

Black, S. M., Kumar, S., Wiseman, D., Ravi, K., Wedgwood, S., Ryzhov, V. & Fineman, J. R., Jul 6 2007, In : Clinical Hemorheology and Microcirculation. 37, 1-2, p. 111-120 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Professor Titus H.J. Huisman and the Medical College of Georgia

Moores, R. R., Apr 1 2007, In : Hemoglobin. 31, 2, p. 187-191 5 p.

Research output: Contribution to journalArticle

Sickle cell disease: A multigenic perspective of a single gene disorder

Kutlar, A., Apr 1 2007, In : Hemoglobin. 31, 2, p. 209-224 16 p.

Research output: Contribution to journalArticle

30 Scopus citations

Spontaneous rupture of the spleen in the presentation of acute myeloid leukemia

Tan, A., Ziari, M., Salman, H. S., Ortega, W. & Cortese, C., Dec 1 2007, In : Journal of Clinical Oncology. 25, 34, p. 5519-5520 2 p.

Research output: Contribution to journalArticle

9 Scopus citations
36 Scopus citations
2006

Antitumor efficacy of DNA vaccination to the epigenetically acting tumor promoting transcription factor BORIS and CD80 molecular adjuvant

Loukinov, D., Ghochikyan, A., Mkrtichyan, M., Ichim, T. E., Lobanenkov, V. V., Cribbs, D. H. & Agadjanyan, M. C., Aug 1 2006, In : Journal of cellular biochemistry. 98, 5, p. 1037-1043 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Effective therapy for a murine model of human anaplastic large-cell lymphoma with the anti-CD30 monoclonal antibody, HeFi-1, does not require activating Fc receptors

Zhang, M., Yao, Z., Zhang, Z., Garmestani, K., Goldman, C. K., Ravetch, J. V., Janik, J. E., Brechbiel, M. W. & Waldmann, T. A., Jul 15 2006, In : Blood. 108, 2, p. 705-710 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Electrophysiological characterization and modeling of the structure activity relationship of the human concentrative nucleoside transporter 3 (hCNT3)

Hu, H., Endres, C. J., Chang, C., Umapathy, N. S., Lee, E. W., Fei, Y. J., Itagaki, S., Swaan, P. W., Ganapathy, V. & Unadkat, J. D., May 1 2006, In : Molecular Pharmacology. 69, 5, p. 1542-1553 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Functional Characteristics of NaS2, a Placenta-specific Na+-coupled Transporter for Sulfate and Oxyanions of the Micronutrients Selenium and Chromium

Miyauchi, S., Srinivas, S. R., Fei, Y. J., Gopal, E., Umapathy, N. S., Wang, H., Conway, S. J., Ganapathy, V. & Prasad, P. D., Jun 1 2006, In : Placenta. 27, 6-7, p. 550-559 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Hb J- Meerut [α 120 (H3) Ala →Glu (α1)] in a Turkish male

Dinçol, G., Güvenç, S., Elam, D., Kutlar, A. & Kutlar, F., Feb 2 2006, In : International Journal of Medical Sciences. 3, 1, p. 26-27 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells

Rosenberg, S. A., Sportès, C., Ahmadzadeh, M., Fry, T. J., Ngo, L. T., Schwarz, S. L., Stetler-Stevenson, M., Morton, K. E., Mavroukakis, S. A., Morre, M., Buffet, R., Mackall, C. L. & Gress, R. E., May 1 2006, In : Journal of Immunotherapy. 29, 3, p. 313-319 7 p.

Research output: Contribution to journalArticle

293 Scopus citations

Phase I Clinical Trial of Costimulated, IL-4 Polarized Donor CD4+ T Cells as Augmentation of Allogeneic Hematopoietic Cell Transplantation

Fowler, D. H., Odom, J., Steinberg, S. M., Chow, C. K., Foley, J., Kogan, Y., Hou, J., Gea-Banacloche, J., Sportes, C., Pavletic, S., Leitman, S., Read, E. J., Carter, C., Kolstad, A., Fox, R., Beatty, G. L., Vonderheide, R. H., Levine, B. L., June, C. H., Gress, R. E. & 1 others, Bishop, M. R., Nov 1 2006, In : Biology of Blood and Marrow Transplantation. 12, 11, p. 1150-1160 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

Preclinical and phase I clinical trial of blockade of IL-15 using Mikβ1 monoclonal antibody in T cell large granular lymphocyte leukemia

Morris, J. C., Janik, J. E., White, J. D., Fleisher, T. A., Brown, M., Tsudo, M., Goldman, C. K., Bryant, B., Petrus, M., Top, L., Lee, C. C., Gao, W. & Waldmann, T. A., Jan 10 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 2, p. 401-406 6 p.

Research output: Contribution to journalArticle

55 Scopus citations

Prototype Alzheimer's disease epitope vaccine induced strong Th2-type anti-Aβ antibody response with Alum to Quil A adjuvant switch

Ghochikyan, A., Mkrtichyan, M., Petrushina, I., Movsesyan, N., Karapetyan, A., Cribbs, D. H. & Agadjanyan, M. G., Mar 20 2006, In : Vaccine. 24, 13, p. 2275-2282 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Regular transfusion lowers plasma free hemoglobin in children with sickle-cell disease at risk for stroke

Lezcano, N. E., Odo, N., Kutlar, A., Brambilla, D. & Adams, R. J., Jun 1 2006, In : Stroke. 37, 6, p. 1424-1426 3 p.

Research output: Contribution to journalArticle

66 Scopus citations

Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells

Weerasinghe, P., Hallock, S., Tang, S. C., Trump, B. & Liepins, A., Aug 15 2006, In : Experimental and Toxicologic Pathology. 58, 1, p. 21-30 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Transcranial Doppler ultrasonography in adults with sickle cell disease

Valadi, N., Silva, G. S., Bowman, L. S., Ramsingh, D., Vicari, P., Filho, A. C., Massaro, A. R., Kutlar, A., Nichols, F. T. & Adams, R. J., Aug 1 2006, In : Neurology. 67, 4, p. 572-574 3 p.

Research output: Contribution to journalArticle

37 Scopus citations

Use of heparin versus lepirudin flushes to prevent withdrawal occlusion of central venous access devices

Horne, M. K., McCloskey, D. J., Calis, K., Wesley, R., Childs, R. & Kasten-Sportes, C., Sep 1 2006, In : Pharmacotherapy. 26, 9 I, p. 1262-1267 6 p.

Research output: Contribution to journalArticle

16 Scopus citations
2005

Adjuvant docetaxel for node-positive breast cancer

Martin, M., Pienkowski, T., Mackey, J., Pawlicki, M., Guastalla, J. P., Weaver, C., Tomiak, E., Al-Tweigeri, T., Chap, L., Juhos, E., Guevin, R., Howell, A., Fornander, T., Hainsworth, J., Coleman, R., Vinholes, J., Modiano, M., Pinter, T., Tang, S. C., Colwell, B. & 12 others, Prady, C., Provencher, L., Walde, D., Rodriguez-Lescure, A., Hugh, J., Loret, C., Rupin, M., Blitz, S., Jacobs, P., Murawsky, M., Riva, A. & Vogel, C., Jun 2 2005, In : New England Journal of Medicine. 352, 22, p. 2302-2313 12 p.

Research output: Contribution to journalArticle

789 Scopus citations

A phase II study of weekly paclitaxel and carboplatin in previously untreated patients with advanced non-small-cell lung cancer

Kallab, A. M., Nalamolu, Y., Dainer, P. M. & Jillella, A. P., Jun 1 2005, In : Medical Oncology. 22, 2, p. 145-151 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

B-cell recovery following rituximab-based therapy is associated with perturbations in stromal derived factor-1 and granulocyte homeostasis

Dunleavy, K., Hakim, F., Kim, H. K., Janik, J. E., Grant, N., Nakayama, T., White, T., Wright, G., Kwak, L., Gress, R., Tosato, G. & Wilson, W. H., Aug 1 2005, In : Blood. 106, 3, p. 795-802 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

Combination therapy for adult T-cell leukemia-xenografted mice: Flavopiridol and anti-CD25 monoclonal antibody

Zhang, M., Zhang, Z., Goldman, C. K., Janik, J. & Waldmann, T. A., Feb 1 2005, In : Blood. 105, 3, p. 1231-1236 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Establishing a platform for immunotherapy: Clinical outcome and study of immune reconstitution after high-dose chemotherapy with progenitor cell support in breast cancer patients

Sportes, C., McCarthy, N. J., Hakim, F., Steinberg, S. M., Liewehr, D. J., Weng, D., Kummar, S., Gea-Banacloche, J., Chow, C. K., Dean, R. M., Castro, K. M., Marchigiani, D., Bishop, M. R., Fowler, D. H. & Gress, R. E., Jun 1 2005, In : Biology of Blood and Marrow Transplantation. 11, 6, p. 472-483 12 p.

Research output: Contribution to journalArticle

14 Scopus citations
41 Scopus citations

High incidence of occult leptomeningeal disease detected by flow cytometry in newly diagnosed aggressive B-cell lymphomas at risk for central nervous system involvement: The role of flow cytometry versus cytology

Hegde, U., Filie, A., Little, R. F., Janik, J. E., Grant, N., Steinberg, S. M., Dunleavy, K., Jaffe, E. S., Abati, A., Stetler-Stevenson, M. & Wilson, W. H., Jan 15 2005, In : Blood. 105, 2, p. 496-502 7 p.

Research output: Contribution to journalArticle

264 Scopus citations