Hematology and Oncology

Research Output 1963 2019

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21 Citations (Scopus)

Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury

Gross, C. M., Rafikov, R., Kumar, S., Aggarwal, S., Ham, P. B., Meadows, M. L., Cherian-Shaw, M., Kangath, A., Sridhar, S., Lucas, R. & Black, S. M., Mar 18 2015, In : PloS one. 10, 3, e0119918.

Research output: Contribution to journalArticle

Acute Lung Injury
Nitric Oxide Synthase Type III
lipopolysaccharides
Lipopolysaccharides
lungs
79 Citations (Scopus)

Endothelial PFKFB3 plays a critical role in angiogenesis

Xu, Y., An, X., Guo, X., Habtetsion, T. G., Wang, Y., Xu, X., Kandala, S., Li, Q., Li, H., Zhang, C., Caldwell, R. B., Fulton, D. J., Su, Y., Hoda, MD. N., Zhou, G., Wu, C. & Huo, Y., Jan 1 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 6, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Protein Isoforms
Glycolysis
Endothelial Cells
Lactic Acid
17 Citations (Scopus)

Endothelin-1 contributes to the progression of renal injury in sickle cell disease via reactive oxygen species

Brett Heimlich, J., Speed, J. S., O'Connor, P. M., Pollock, J. S., Townes, T. M., Meiler, S. E., Kutlar, A. & Pollock, D. M., Jan 1 2016, In : British Journal of Pharmacology. 173, 2, p. 386-395 10 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Endothelin-1
Reactive Oxygen Species
Kidney
Wounds and Injuries
30 Citations (Scopus)

Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase

Sun, X., Kumar, S., Sharma, S., Aggarwal, S., Lu, Q., Gross, C., Rafikova, O., Lee, S. G., Dasarathy, S., Hou, Y., Meadows, M. L., Han, W., Su, Y., Fineman, J. R. & Black, S. M., Jan 1 2014, In : American journal of respiratory cell and molecular biology. 50, 6, p. 1084-1095 12 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Endothelial cells
Endothelin-1
Pulmonary Hypertension
Endothelial Cells
13 Citations (Scopus)

Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167

Rafikov, R., Kumar, S., Aggarwal, S., Hou, Y., Kangath, A., Pardo, D., Fineman, J. R. & Black, S. M., Feb 1 2014, In : Free Radical Biology and Medicine. 67, p. 255-264 10 p.

Research output: Contribution to journalArticle

Phosphorylation
Endothelin-1
Catalase
Serine
Protein Kinase C
35 Citations (Scopus)

Enhanced assessment of allogeneic bone marrow transplant engraftment using automated fluorescent-based typing

Pindolia, K., Janakiraman, N., Kasten-Sportes, C., Demanet, C., Van Waeyenberge, C., Pals, G. & Worsham, M. J., Jan 1 1999, In : Bone marrow transplantation. 24, 11, p. 1235-1241 7 p.

Research output: Contribution to journalArticle

Chimerism
Bone Marrow
Transplants
DNA
Unrelated Donors
23 Citations (Scopus)
Apoptosis Regulatory Proteins
Smoke
Tobacco Products
DNA Damage
Apoptosis
15 Citations (Scopus)

Enhanced therapeutic efficacy and memory of tumor-specific CD8 T cells by ex vivo PI3K-δ inhibition

Abu Eid, R., Ahmad, S., Lin, Y., Webb, M., Berrong, Z., Shrimali, R. K., Kumai, T., Ananth, S., Rodriguez, P. C., Celis, E., Janik, J. E., Mkrtichyan, M. & Khleif, S. N., Aug 1 2017, In : Cancer Research. 77, 15, p. 4135-4145 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
T-Lymphocytes
Aptitude
Neoplasms
Protein Isoforms
128 Citations (Scopus)

eNOS activation and NO function: Structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity

Rafikov, R., Fonseca, F. V., Kumar, S., Pardo, D., Darragh, C., Elms, S., Fulton, D. & Black, S. M., Sep 1 2011, In : Journal of Endocrinology. 210, 3, p. 271-284 14 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Nucleic Acid Regulatory Sequences
Post Translational Protein Processing
Superoxides
Oxidative Stress
100 Citations (Scopus)

ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets

Wright, P. W., Bolling, L. C., Calvert, M. E., Sarmento, O. F., Berkeley, E. V., Shea, M. C., Hao, Z., Jayes, F. C., Bush, L. A., Shetty, J., Shore, A. N., Reddi, P. P., Tung, K. S., Samy, E., Allietta, M. M., Sherman, N. E., Herr, J. C. & Coonrod, S. A., Apr 1 2003, In : Developmental Biology. 256, 1, p. 74-89 16 p.

Research output: Contribution to journalArticle

Oocytes
Ovum
Embryonic Structures
Proteins
Keratins
29 Citations (Scopus)

Epigenetic regulation of HYAL-1 hyaluronidase expression: Identification of HYAL-1 promoter

Lokeshwar, V. B., Gomez, P., Kramer, M., Knapp, J., McCornack, M. A., Lopez, L. E., Fregien, N., Dhir, N., Scherer, S., Klumpp, D. J., Manoharan, M., Soloway, M. S. & Lokeshwar, B. L., Oct 24 2008, In : Journal of Biological Chemistry. 283, 43, p. 29215-29227 13 p.

Research output: Contribution to journalArticle

Hyaluronoglucosaminidase
Epigenomics
Transcription Initiation Site
Tissue
Methylation
9 Citations (Scopus)

Epoetin alfa in patients not on chemotherapy - Canadian data

Quirt, I., Robeson, C., Lau, C. Y., Kovacs, M., Burdette-Radoux, S., Dolan, S., Tang, S-C., McKenzie, M. & Couture, F., Jan 1 2002, In : Seminars in Oncology. 29, 3 SUPPL. 8, p. 75-80 6 p.

Research output: Contribution to journalArticle

Epoetin Alfa
Drug Therapy
Anemia
Hemoglobins
Quality of Life
136 Citations (Scopus)

Epoetin alfa therapy increases hemoglobin levels and improves quality of life in patients with cancer-related anemia who are not receiving chemotherapy and patients with anemia who are receiving chemotherapy

Quirt, I., Robeson, C., Lau, C. Y., Kovacs, M., Burdette-Radoux, S., Dolan, S., Tang, S-C., McKenzie, M. & Couture, F., Nov 1 2001, In : Journal of Clinical Oncology. 19, 21, p. 4126-4134 9 p.

Research output: Contribution to journalArticle

Epoetin Alfa
Anemia
Hemoglobins
Quality of Life
Drug Therapy
685 Citations (Scopus)

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

Kochenderfer, J. N., Wilson, W. H., Janik, J. E., Dudley, M. E., Stetler-Stevenson, M., Feldman, S. A., Maric, I., Raffeld, M., Nathan, D. A. N., Lanier, B. J., Morgan, R. A. & Rosenberg, S. A., Nov 18 2010, In : Blood. 116, 20, p. 4099-4102 4 p.

Research output: Contribution to journalArticle

CD19 Antigens
T-cells
Antigen Receptors
Lymphoma
T-Cell Antigen Receptor
50 Citations (Scopus)

Erythrocyte sickling during exercise and thermal stress

Bergeron, M. F., Cannon, J. G., Hall, E. L. & Kutlar, A., Nov 1 2004, In : Clinical Journal of Sport Medicine. 14, 6, p. 354-356 3 p.

Research output: Contribution to journalArticle

Hot Temperature
Erythrocytes
Exercise
Peroxidase
Heart Rate
2 Citations (Scopus)

Erythropoiesis inhibitory factor(s) from human plasma and urine: The production and application of a neutralizing anti-EIF serum

Garver, F. A., Neal, W. A., Lewis, J. P., Grenett, H. E., Lutcher, C. L., Ozawa, T., Moores, R. R. & Wright, C. S., Jan 1 1981, In : Biochemical Medicine. 25, 2, p. 174-185 12 p.

Research output: Contribution to journalArticle

Plasma (human)
Erythropoiesis
Urine
Plasmas
Polycythemia
11 Citations (Scopus)

Erythropoiesis Stimulating Factors

Lewis, J. P., Alford, D. A., Neal, W. A., Moores, R. R., Welch, E. T., Gardner, E., Wright, CS. S. & Smith, L. L., Jan 1 1971, In : Scandinavian Journal of Haematology. 8, 3, p. 200-209 10 p.

Research output: Contribution to journalArticle

Erythropoiesis
Glycoproteins
Dialysis
Hexosamines
Fucose
15 Citations (Scopus)

Erythropoietin assay with posthypoxic-polycythemic mice.

Lewis, J. P., Neal, W. A., Alford, D. A., Moores, R. R., Gardner, E., Welch, E. T., Wright, C. S. & McWhirter, J. D., May 1 1970, In : American Journal of Veterinary Research. 31, 5, p. 891-893 3 p.

Research output: Contribution to journalArticle

Rodent Diseases
polycythemia
erythropoietin
Polycythemia
Erythropoietin
31 Citations (Scopus)

Erythropoietin production. A potential marker for interleukin‐2/interferon‐responsive tumors

Janik, J. E., Sharfman, W. H., Smitht, J. W., Longo, D. L., Sznol, M., Urba, W. J., Figlin, R., Pierce, W. C., Bukowski, R. M., Fyfe, G. & Belldegrun, A., Jan 1 1993, In : Cancer. 72, 9, p. 2656-2659 4 p.

Research output: Contribution to journalArticle

Erythropoietin
Renal Cell Carcinoma
Neoplasms
Polycythemia
Hyperthyroidism
16 Citations (Scopus)

Escape from suppression: Tumor-specific effector cells outcompete regulatory T cells following stem-cell transplantation

Mirmonsef, P., Tan, G., Zhou, G., Morino, T., Noonan, K., Borrello, I. & Levitsky, H. I., Feb 15 2008, In : Blood. 111, 4, p. 2112-2121 10 p.

Research output: Contribution to journalArticle

Tumor Escape
Transplantation (surgical)
T-cells
Stem Cell Transplantation
Regulatory T-Lymphocytes
14 Citations (Scopus)

Establishing a platform for immunotherapy: Clinical outcome and study of immune reconstitution after high-dose chemotherapy with progenitor cell support in breast cancer patients

Sportes, C., McCarthy, N. J., Hakim, F., Steinberg, S. M., Liewehr, D. J., Weng, D., Kummar, S., Gea-Banacloche, J., Chow, C. K., Dean, R. M., Castro, K. M., Marchigiani, D., Bishop, M. R., Fowler, D. H. & Gress, R. E., Jun 1 2005, In : Biology of Blood and Marrow Transplantation. 11, 6, p. 472-483 12 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Immunotherapy
Stem Cells
Outcome Assessment (Health Care)
Breast Neoplasms
125 Citations (Scopus)

Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism

Tanaka, K., Hao, Z., Kai, M. & Okayama, H., Oct 15 2001, In : EMBO Journal. 20, 20, p. 5779-5790 12 p.

Research output: Contribution to journalArticle

Chromatids
Schizosaccharomyces
Yeast
Maintenance
DNA
8 Citations (Scopus)
GTP Cyclohydrolase
Response Elements
Guanosine Triphosphate
Cyclic AMP
Estradiol
26 Citations (Scopus)
Acetylation
Histones
Ethanol
Cytoskeleton
Memory Disorders
3 Citations (Scopus)

Evaluation of romiplostim for the treatment of secondary failure of platelet recovery among allogeneic hematopoietic stem cell transplant patients

Hartranft, M. E., Clemmons, A. B., Deremer, D. L. & Kota, V., Jan 1 2017, In : Journal of Oncology Pharmacy Practice. 23, 1, p. 10-17 8 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Treatment Failure
Blood Platelets
Transplants
Thrombopoietin Receptors
125 Citations (Scopus)

Evidence that monoclonal antibodies against CD9 antigen induce specific association between CD9 and the platelet glycoprotein IIb-IIIa complex

Slupsky, J. R., Seehafer, J. G., Tang, S. C., Masellis-Smith, A. & Shaw, A. R. E., Jan 1 1989, In : Journal of Biological Chemistry. 264, 21, p. 12289-12293 5 p.

Research output: Contribution to journalArticle

CD9 Antigen
Integrin beta3
Platelet Membrane Glycoproteins
Platelet Glycoprotein GPIIb-IIIa Complex
Platelets
5 Citations (Scopus)

Exercise capacity as an independent risk factor for adverse cardiovascular outcomes among nondiabetic and diabetic patients

Pierre-Louis, B., Guddati, A. K., Syed, M. K. H., Gorospe, V. E., Manguerra, M., Bagchi, C., Aronow, W. S. & Ahn, C., Feb 1 2014, In : Archives of Medical Science. 10, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

Exercise
Stroke
Myocardial Infarction
Myocardial Ischemia
Coronary Artery Disease
16 Citations (Scopus)

Exercise in sickle cell anemia: Effect on inflammatory and vasoactive mediators

Barbeau, P., Woods, K. F., Ramsey, L. T., Litaker, M. S., Pollock, D. M., Pollock, J. S., Callahan, L. A., Kutlar, A., Mensah, G. A. & Gutin, B., Jan 1 2001, In : Endothelium: Journal of Endothelial Cell Research. 8, 2, p. 147-155 9 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Exercise
Nitric Oxide
Endothelin-1
C-Reactive Protein
59 Citations (Scopus)

Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues. A TSSK member is present in the equatorial segment of human sperm

Hao, Z., Jha, K. N., Kim, Y. H., Vemuganti, S., Westbrook, V. A., Chertihin, O., Markgraf, K., Flickinger, C. J., Coppola, M., Herr, J. C. & Visconti, P. E., Jun 1 2004, In : Molecular Human Reproduction. 10, 6, p. 433-444 12 p.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
Spermatozoa
Testis
Phosphotransferases
Northern Blotting
40 Citations (Scopus)
Glutamine
Protein Isoforms
system N protein 1
Messenger RNA
Substrate Specificity
16 Citations (Scopus)

Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells

Umapathy, N. S., Dun, Y., Martin, P. M., Duplantier, J. N., Roon, P., Prasad, P., Smith, S. B. & Ganapathy, V., Nov 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 5151-5160 10 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Glutamine
Ganglia
Neuroglia
In Situ Hybridization
72 Citations (Scopus)

Expression of BAG-1 in invasive breast carcinomas

Tang, S. C., Shaheta, N., Chernenko, G., Khalifa, M. & Wang, X., Jun 1 1999, In : Journal of Clinical Oncology. 17, 6, p. 1710-1719 10 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Disease-Free Survival
Newfoundland and Labrador
Survival
Progesterone Receptors
20 Citations (Scopus)

Expression of cellular genes in HPV16-immortalized and cigarette smoke condensate-transformed human endocervical cells

Yang, X., Nakao, Y., Pater, M. M., Tang, S-C. & Pater, A., Sep 1 1997, In : Journal of cellular biochemistry. 66, 3, p. 309-321 13 p.

Research output: Contribution to journalArticle

Smoke
Tobacco Products
Genes
Proliferating Cell Nuclear Antigen
Gene Expression
56 Citations (Scopus)

Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma

Rojiani, M. V., Alidina, J., Esposito, N. & Rojiani, A. M., Dec 1 2010, In : International Journal of Clinical and Experimental Pathology. 3, 8, p. 775-781 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Central Nervous System
Neoplasm Metastasis
Carcinoma
Lung
4 Citations (Scopus)

Extracavitary manifestation of primary effusion lymphoma as a right atrial mass

Marak, C. P., Ponea, A. M., Shim, C., Shaheen, S. & Guddati, A. K., Jan 1 2013, In : Case Reports in Oncology. 6, 1, p. 114-118 5 p.

Research output: Contribution to journalArticle

Primary Effusion Lymphoma
Pleural Effusion
Viruses
Light
Pericardial Effusion

Extreme Prostate-Specific Antigen Response to Infusional 5-Flourouracil in Castrate-Resistant Prostate Cancer

Manogue, C., Ledet, E., Guddati, A. K., Lewis, B. & Sartor, O., Mar 1 2018, In : Oncologist. 23, 3, p. 383-385 3 p.

Research output: Contribution to journalArticle

Prostate-Specific Antigen
Prostatic Neoplasms
Fluorouracil
Folic Acid Antagonists
Androgens
11 Citations (Scopus)

Factors predicting survival in peripheral T-cell lymphoma in the USA: A population-based analysis of 8802 patients in the modern era

Petrich, A. M., Helenowski, I. B., Bryan, L. J., Rozell, S. A., Galamaga, R. & Nabhan, C., Mar 1 2015, In : British Journal of Haematology. 168, 5, p. 708-718 11 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Survival
Population
Histology
Epidemiology
46 Citations (Scopus)

Fatty acid metabolism and cell proliferation. V. Evaluation of pathways for the generation of lipid peroxides

Morisaki, N., Lindsey, J. A., Stitts, J. M., Zhang, H. & Cornwell, D. G., Jun 1 1984, In : Lipids. 19, 6, p. 381-394 14 p.

Research output: Contribution to journalArticle

fatty acid metabolism
Lipid Peroxides
Cell proliferation
Malondialdehyde
peroxides
31 Citations (Scopus)

Fatty acid metabolism and cell proliferation. VII. Antioxidant effects of tocopherols and their quinones

Lindsey, J. A., Zhang, H., Kaseki, H., Morisaki, N., Sato, T. & Cornwell, D. G., Mar 1 1985, In : Lipids. 20, 3, p. 151-157 7 p.

Research output: Contribution to journalArticle

Quinones
Tocopherols
Cell proliferation
Metabolism
Fatty Acids

Fatty acid release: A mechanism for diminished immunosurveillance and cytotoxicity with cyclosporine A

Kaseki, H., Zhang, H. & Lindsey, J. A., Jan 1 1985, In : Federation Proceedings. 44, 3

Research output: Contribution to journalArticle

Immunologic Monitoring
Cyclosporine
Fatty Acids
58 Citations (Scopus)

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

Elliott, N. E., Cleveland, S. M., Grann, V., Janik, J., Waldmann, T. A. & Davé, U. P., Oct 6 2011, In : Blood. 118, 14, p. 3911-3921 11 p.

Research output: Contribution to journalArticle

Adult T Cell Leukemia Lymphoma
T-cells
Mutation
Chemotherapy
Genetic Association Studies
8 Citations (Scopus)

Ferroportin q248h, dietary iron, and serum ferritin in community African-Americans with low to high alcohol consumption

Gordeuk, V. R., Diaz, S. F., Onojobi, G. O., Kasvosve, I., Debebe, Z., Edossa, A., Pantin, J. M., Xiong, S., Nekhai, S., Nouraie, M., Tsukamoto, H. & Taylor, R. E., Nov 1 2008, In : Alcoholism: Clinical and Experimental Research. 32, 11, p. 1947-1953 7 p.

Research output: Contribution to journalArticle

Dietary Iron
Ferritins
Alcohol Drinking
African Americans
Alcohols
4 Citations (Scopus)

Fetal hemoglobin heterogeneity in chinese newborns of the uygur and han nationalities; comparisons of babies from xinjiang and Beijing

Chu, Z. F., Liang, C. C., Kutlar, F. & Huisman, T. H. J., Jan 1 1987, In : Hemoglobin. 11, 2, p. 123-128 6 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Chromosome Mapping
Ethnic Groups
Restriction Fragment Length Polymorphisms
China
118 Citations (Scopus)

Fetal hemoglobin in normal adults and β-thalassemia heterozygotes

Kutlar, A., Kutlar, F., Gu, L. G., Mayson, S. M. & Huisman, T. H. J., Jun 1 1990, In : Human Genetics. 85, 1, p. 106-110 5 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Thalassemia
Heterozygote
Mutation
Codon
85 Citations (Scopus)

Fetal hemoglobin in sickle cell anemia: Genetic determinants of response to hydroxyurea

Ma, Q., Wyszynski, D. F., Farrell, J. J., Kutlar, A., Farrer, L. A., Baldwin, C. T. & Steinberg, M. H., Dec 1 2007, In : Pharmacogenomics Journal. 7, 6, p. 386-394 9 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Hydroxyurea
Sickle Cell Anemia
Single Nucleotide Polymorphism
Genes

Fifth Atlantic Canada Oncology Group Winter Symposium

Tang, S-C. & Champion, P., Nov 14 2001, In : Current Oncology. 8, 2, p. 83-94 12 p.

Research output: Contribution to journalArticle

Canada
6 Citations (Scopus)

First observation of haemoglobin Malay alpha 2B2 26 (B1) Asn----Ser--a case report.

George, E., Huisman, T. H., Yang, K. G., Kutlari, F., Wilson, J. B., Kutlar, A., Storming, T. A., Gonzales-Redondo, J. M., Faridah, K. & Khalid, A. K., Sep 1 1989, In : Medical Journal of Malaysia. 44, 3, p. 259-262 4 p.

Research output: Contribution to journalArticle

Hemoglobins
Observation
Codon
Mutation
hemoglobin Malay
17 Citations (Scopus)

Five adults with mild sickle cell anemia share a βs chromosome with the same haplotype

Bakioglu, I., Hattori, Y., Kutlar, A., Mathew, C. & Huisman, T. H. J., Jan 1 1985, In : American Journal of Hematology. 20, 3, p. 297-300 4 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Haplotypes
Chromosomes
Qatar
Thalassemia
18 Citations (Scopus)

Flow cytometric analysis of androgen receptor expression in human prostate tumors and benign tissues

Krishan, A., Oppenheimer, A., You, W., Dubbin, R., Sharma, D. & Lokeshwar, B. L., May 1 2000, In : Clinical Cancer Research. 6, 5, p. 1922-1930 9 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostate
Neoplasms
Aneuploidy
Genetic Markers
21 Citations (Scopus)

Flow cytometric immunophenotypic assessment of T-cell clonality by V β repertoire analysis: Detection of T-cell clonality at diagnosis and monitoring of minimal residual disease following therapy

Tembhare, P., Yuan, C. M., Xi, L., Morris, J. C., Liewehr, D., Venzon, D., Janik, J. E., Raffeld, M. & Stetler-Stevenson, M., Jun 1 2011, In : American Journal of Clinical Pathology. 135, 6, p. 890-900 11 p.

Research output: Contribution to journalArticle

Residual Neoplasm
T-Cell Antigen Receptor
T-Lymphocytes
Therapeutics
Neoplasms