Hematology and Oncology

Research Output 1963 2019

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2017
3 Citations (Scopus)

Allogeneic transplantation using CD34+ selected peripheral blood progenitor cells combined with non-mobilized donor T cells for refractory severe aplastic anaemia

Purev, E., Tian, X., Aue, G., Pantin, J., Vo, P., Shalabi, R., Reger, R. N., Cook, L., Ramos, C., Cho, E., Worthy, T., Khuu, H., Stroncek, D., Young, N. S. & Childs, R. W., Mar 1 2017, In : British Journal of Haematology. 176, 6, p. 950-960 11 p.

Research output: Contribution to journalArticle

Aplastic Anemia
Homologous Transplantation
Graft vs Host Disease
Blood Cells
Stem Cells
5 Citations (Scopus)

Analysis of risk factors for post-operative complications and prognostic predictors of disease recurrence following definitive treatment of patients with esophageal cancer from two medical centers in Northwest China

Wang, J., Zhang, B., Meng, J., Xiao, G., Li, X., Li, G., Qin, S., Du, N., Zhang, J., Zhang, J., Xu, C., Tang, S-C., Liang, R., Ren, H. & Sun, X., Jan 1 2017, In : Experimental and Therapeutic Medicine. 14, 3, p. 2584-2594 11 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
China
Recurrence
Cardiovascular Abnormalities
Esophagus
7 Citations (Scopus)

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

Mangaonkar, A., Mondal, A. K., Fulzule, S., Pundkar, C., Park, E. J., Jillella, A., Kota, V., Xu, H., Savage, N. M., Shi, H., Munn, D. & Kolhe, R., Dec 1 2017, In : Scientific Reports. 7, 1, 12892.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Acute Myeloid Leukemia
Mortality
Messenger RNA
Bone Marrow
1 Citation (Scopus)

Anti-HER-2 therapy following severe trastuzumab-induced cardiac toxicity

Sadek, I., Keaton, M., Maihle, N. J. & Tang, S. C., Sep 1 2017, In : Genes and Diseases. 4, 3, p. 159-162 4 p.

Research output: Contribution to journalArticle

Toxicity
Thoracic Wall
Breast Neoplasms
Therapeutics
Disease control
21 Citations (Scopus)

A phase 1b/2b multicenter study of oral panobinostat plus azacitidine in adults with MDS, CMML or AML with ≤30% blasts

Garcia-Manero, G., Sekeres, M. A., Egyed, M., Breccia, M., Graux, C., Cavenagh, J. D., Salman, H., Illes, A., Fenaux, P., Deangelo, D. J., Stauder, R., Yee, K., Zhu, N., Lee, J. H., Valcarcel, D., Macwhannell, A., Borbenyi, Z., Gazi, L., Acharyya, S., Ide, S. & 2 others, Marker, M. & Ottmann, O. G., Jan 1 2017, In : Leukemia. 31, 12, p. 2799-2806 8 p.

Research output: Contribution to journalArticle

Azacitidine
Myelodysplastic Syndromes
Multicenter Studies
Maximum Tolerated Dose
panobinostat
5 Citations (Scopus)

cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium

Wang, R., Islam, B. N., Bridges, A., Sharman, S. K., Hu, M., Hou, Y., Somanath, P. R., Venable, L., Singh, N., Kim, S., Sridhar, S., Hofmann, F. & Browning, D. D., Feb 1 2017, In : American Journal of Pathology. 187, 2, p. 377-389 13 p.

Research output: Contribution to journalArticle

Colon
Epithelium
Antioxidants
Gene Expression
Colonic Neoplasms
3 Citations (Scopus)

Clinical Application of Detecting 21-Gene Recurrence Score in Predicating Prognosis and Therapy Response of Patients with Breast Cancer from Two Medical Centers

Xiao, G., Meng, J., Zhang, J., Li, G., Du, N., Qin, S., Wang, J., Xu, C., Ren, H., Tang, S-C. & Sun, X., Nov 26 2017, In : Cancer Investigation. 35, 10, p. 639-646 8 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Recurrence
Genes
Therapeutics
Precision Medicine
50 Citations (Scopus)

Concurrent PD-1 blockade negates the effects of OX40 agonist antibody in combination immunotherapy through inducing T-cell apoptosis

Shrimali, R. K., Ahmad, S., Verma, V., Zeng, P., Ananth, S., Gaur, P., Gittelman, R. M., Yusko, E., Sanders, C., Robins, H., Hammond, S. A., Janik, J. E., Mkrtichyan, M., Gupta, S. & Khleif, S. N., Sep 2017, In : Cancer Immunology Research. 5, 9, p. 755-766 12 p.

Research output: Contribution to journalArticle

Immunotherapy
Apoptosis
T-Lymphocytes
Antibodies
Vaccines
140 Citations (Scopus)

Crizanlizumab for the prevention of pain crises in sickle cell disease

Ataga, K. I., Kutlar, A., Kanter, J., Liles, D., Cancado, R., Friedrisch, J., Guthrie, T. H., Knight-Madden, J., Alvarez, O. A., Gordeuk, V. R., Gualandro, S., Colella, M. P., Smith, W. R., Rollins, S. A., Stocker, J. W. & Rother, R. P., Feb 2 2017, In : New England Journal of Medicine. 376, 5, p. 429-439 11 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Placebos
Pain
Acute Chest Syndrome
P-Selectin
25 Citations (Scopus)

Differential PI3Kδ signaling in CD4+ T-cell subsets enables selective targeting of t regulatory cells to enhance cancer immunotherapy

Ahmad, S., Abu-Eid, R., Shrimali, R. K., Webb, M., Verma, V., Doroodchi, A., Berrong, Z., Samara, R., Rodriguez, P. C., Mkrtichyan, M. & Khleif, S. N., Apr 15 2017, In : Cancer Research. 77, 8, p. 1892-1904 13 p.

Research output: Contribution to journalArticle

T-Lymphocyte Subsets
Phosphatidylinositol 3-Kinases
Immunotherapy
Neoplasms
T-Lymphocytes
7 Citations (Scopus)

Does the frequency of molecular monitoring after tyrosine kinase inhibitor discontinuation affect outcomes of patients with chronic myeloid leukemia?

Kong, J. H., Winton, E. F., Heffner, L. T., Chen, Z., Langston, A. A., Hill, B., Arellano, M., El-Rassi, F., Kim, A., Jillella, A., Kota, V., Bodó, I. & Khoury, H. J., Jul 1 2017, In : Cancer. 123, 13, p. 2482-2488 7 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Protein-Tyrosine Kinases
Reverse Transcriptase Polymerase Chain Reaction
Therapeutics
Confidence Intervals
17 Citations (Scopus)

Effect of high-dose plerixafor on CD34+ cell mobilization in healthy stem cell donors: Results of a randomized crossover trial

Pantin, J., Purev, E., Tian, X., Cook, L., Donohue-Jerussi, T., Cho, E., Reger, R., Hsieh, M., Khuu, H., Calandra, G., Geller, N. L. & Childs, R. W., Feb 28 2017, In : Haematologica. 102, 3, p. 600-609 10 p.

Research output: Contribution to journalArticle

Cross-Over Studies
Stem Cells
Homologous Transplantation
Area Under Curve
Cell Count
249 Citations (Scopus)

Efficacy and safety of durvalumab in locally advanced or metastatic urothelial carcinoma: Updated results from a phase 1/2 open-label study

Powles, T., O'Donnell, P. H., Massard, C., Arkenau, H. T., Friedlander, T. W., Hoimes, C. J., Lee, J. L., Ong, M., Sridhar, S. S., Vogelzang, N. J., Fishman, M. N., Zhang, J., Srinivas, S., Parikh, J., Antal, J., Jin, X., Gupta, A. K., Ben, Y. & Hahn, N. M., Sep 2017, In : JAMA Oncology. 3, 9, e172411.

Research output: Contribution to journalArticle

Carcinoma
Safety
Cell Death
Therapeutics
Ligands
16 Citations (Scopus)

Enhanced therapeutic efficacy and memory of tumor-specific CD8 T cells by ex vivo PI3K-δ inhibition

Abu Eid, R., Ahmad, S., Lin, Y., Webb, M., Berrong, Z., Shrimali, R. K., Kumai, T., Ananth, S., Rodriguez, P. C., Celis, E., Janik, J. E., Mkrtichyan, M. & Khleif, S. N., Aug 1 2017, In : Cancer Research. 77, 15, p. 4135-4145 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
T-Lymphocytes
Aptitude
Neoplasms
Protein Isoforms
8 Citations (Scopus)

Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016

Ascierto, P. A., Agarwala, S. S., Ciliberto, G., Demaria, S., Dummer, R., Duong, C. P. M., Ferrone, S., Formenti, S. C., Garbe, C., Halaban, R., Khleif, S. N., Luke, J. J., Mir, L. M., Overwijk, W. W., Postow, M., Puzanov, I., Sondel, P., Taube, J. M., Thor Straten, P., Stroncek, D. F. & 3 others, Wargo, J. A., Zarour, H. & Thurin, M., Nov 16 2017, In : Journal of Translational Medicine. 15, 1, 236.

Research output: Contribution to journalArticle

T-cells
Tumors
Melanoma
Lymphocytes
Chemokine Receptors
44 Citations (Scopus)

Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

Kolhe, R. B., Hunter, D. M., Liu, S., Jadeja, R. N., Pundkar, C., Mondal, A. K., Mendhe, B., Drewry, M., Rojiani, M. V., Liu, Y., Isales, C. M., Guldberg, R. E., Hamrick, M. W. & Fulzele, S. T., Dec 1 2017, In : Scientific reports. 7, 1, 2029.

Research output: Contribution to journalArticle

Synovial Fluid
MicroRNAs
Osteoarthritis
Exosomes
Encyclopedias
1 Citation (Scopus)

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with index of hydroxyurea responsiveness

Zhu, X., Hu, T., Ho, M. H., Wang, Y., Yu, M., Patel, N., Pi, W., Choi, J-H., Xu, H., Ganapathy, V., Kutlar, F., Kutlar, A. & Tuan Lo, D., Nov 30 2017, In : Haematologica. 102, 12, p. 1995-2004 10 p.

Research output: Contribution to journalArticle

Erythroblasts
Hydroxyurea
Globins
Sickle Cell Anemia
Genes
2 Citations (Scopus)

Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury

Kumar, S., Sun, X., Noonepalle, S. K., Lu, Q., Zemskov, E. A., Wang, T., Aggarwal, S., Gross, C., Sharma, S., Desai, A. A., Hou, Y., Dasarathy, S., Qu, N., Reddy, V., Lee, S. G., Cherian-Shaw, M., Yuan, J. X. J., Catravas, J. D., Rafikov, R., Garcia, J. G. N. & 1 others, Black, S. M., Jan 1 2017, In : Free Radical Biology and Medicine. 102, p. 217-228 12 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Lipopolysaccharides
Nitric Oxide
Chemical activation
Nitric Oxide Synthase Type III
10 Citations (Scopus)

Immunotherapy biomarkers 2016: Overcoming the barriers

Gulley, J. L., Berzofsky, J. A., Butler, M. O., Cesano, A., Fox, B. A., Gnjatic, S., Janetzki, S., Kalavar, S., Karanikas, V., Khleif, S. N., Kirsch, I., Lee, P. P., Maccalli, C., Maecker, H., Schlom, J., Seliger, B., Siebert, J., Stroncek, D. F., Thurin, M., Yuan, J. & 1 others, Butterfield, L. H., Mar 21 2017, In : Journal for ImmunoTherapy of Cancer. 5, 1, 29.

Research output: Contribution to journalArticle

Immunotherapy
Biomarkers
National Cancer Institute (U.S.)
National Institutes of Health (U.S.)
Technology
10 Citations (Scopus)

Inhibition of androgen receptor promotes CXC-chemokine receptor 7-mediated prostate cancer cell survival

Hoy, J. J., Kallifatidis, G., Smith, D. K. & Lokeshwar, B. L., Dec 1 2017, In : Scientific reports. 7, 1, 3058.

Research output: Contribution to journalArticle

CXCR Receptors
CXC Chemokines
Chemokine Receptors
Androgen Receptors
Prostatic Neoplasms

Intracranial Germinoma: Systemic Chemotherapy in Addition to Dose-Reduced Radiation Therapy

Chiec, L., Curry, R. & Karim, N. A., Jan 1 2017, In : American journal of therapeutics. 24, 5, p. e609-e610

Research output: Contribution to journalArticle

18 Citations (Scopus)

Label-free ferrohydrodynamic cell separation of circulating tumor cells

Zhao, W., Cheng, R., Jenkins, B. D., Zhu, T., Okonkwo, N. E., Jones, C. E., Davis, M. B., Kavuri, S. K., Hao, Z., Schroeder, C. & Mao, L., Jan 1 2017, In : Lab on a Chip. 17, 18, p. 3097-3111 15 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Cell Separation
Labels
Tumors
Cells
29 Citations (Scopus)

LiGa5O8:Cr-based theranostic nanoparticles for imaging-guided X-ray induced photodynamic therapy of deep-seated tumors

Chen, H., Sun, X., Wang, G. D., Nagata, K., Hao, Z., Wang, A., Li, Z., Xie, J. & Shen, B., Nov 2017, In : Materials Horizons. 4, 6, p. 1092-1101 10 p.

Research output: Contribution to journalArticle

Photodynamic therapy
Tumors
Nanoparticles
Imaging techniques
X rays
23 Citations (Scopus)

Long-term endothelin-a receptor antagonism provides robust renal protection in humanized sickle cell disease mice

Kasztan, M., Fox, B. M., Speed, J. S., De Miguel, C., Gohar, E. Y., Townes, T. M., Kutlar, A., Pollock, J. S. & Pollock, D. M., Aug 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2443-2458 16 p.

Research output: Contribution to journalArticle

Endothelin Receptors
Sickle Cell Anemia
Kidney
Endothelin A Receptors
Albuminuria
2 Citations (Scopus)

Managing acute promyelocytic leukemia in patients belonging to the Jehovah’s witness congregation

Jillella, A. P., Arellano, M. L., Heffner, L. T., Gaddh, M., Langston, A. A., Khoury, H. J., Mangoankar, A. & Kota, V. K., Sep 26 2017, In : Hematology Reports. 9, 3, p. 102-105 4 p., 7083.

Research output: Contribution to journalArticle

Jehovah's Witnesses
Acute Promyelocytic Leukemia
Mortality
Disseminated Intravascular Coagulation
Leukemia
8 Citations (Scopus)

MiR-129 blocks estrogen induction of NOTCH signaling activity in breast cancer stem-like cells

Xiao, G., Li, X., Li, G., Zhang, B., Xu, C., Qin, S., Du, N., Wang, J., Tang, S-C., Zhang, J., Ren, H., Chen, K. & Sun, X., Jan 1 2017, In : Oncotarget. 8, 61, p. 103261-103273 13 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Cyclin D1
Estrogens
Stem Cells
Estrogen Receptor alpha
13 Citations (Scopus)

miR-367 stimulates Wnt cascade activation through degrading FBXW7 in NSCLC stem cells

Xiao, G., Zhang, B., Meng, J., Wang, J., Xu, C., Tang, S-C., Li, X., Zhang, J., Liang, R., Ren, H. & Sun, X., Dec 17 2017, In : Cell Cycle. 16, 24, p. 2374-2385 12 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Neoplastic Stem Cells
Stem Cells
Wnt Proteins
Wnt Signaling Pathway
64 Citations (Scopus)

Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade

Ouzounova, M., Lee, E., Piranlioglu, R., El Andaloussi, A., Kolhe, R., Demirci, M. F., Marasco, D., Asm, I., Chadli, A., Hassan, K. A., Thangaraju, M., Zhou, G., Arbab, A. S., Cowell, J. K. & Korkaya, H., Apr 6 2017, In : Nature Communications. 8, 14979.

Research output: Contribution to journalArticle

suppressors
plastic properties
Plasticity
Tumors
cascades
Melanosis
Cerebellar Nuclei
Pigmentation
Astrocytes
Cerebellum
13 Citations (Scopus)

Nano Let.7b sensitization of eliminating esophageal cancer stem.like cells is dependent on blockade of Wnt activation of symmetric division

Pang, Y., Liu, J., Li, X., Zhang, Y., Zhang, B., Zhang, J., Du, N., Xu, C., Liang, R., Ren, H., Tang, S-C. & Sun, X., Oct 2017, In : International journal of oncology. 51, 4, p. 1077-1088 12 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Neoplastic Stem Cells
Stem Cells
docetaxel
Therapeutics
13 Citations (Scopus)

Phase II study of alemtuzumab (CAMPATH-1) in patients with HTLV-1-associated adult T-cell leukemia/lymphoma

Sharma, K., Janik, J. E., O'Mahony, D., Stewart, D., Pittaluga, S., Stetler-Stevenson, M., Jaffe, E. S., Raffeld, M., Fleisher, T. A., Lee, C. C., Steinberg, S. M., Waldmann, T. A. & Morris, J. C., Jan 1 2017, In : Clinical Cancer Research. 23, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

Adult T Cell Leukemia Lymphoma
Human T-lymphotropic virus 1
T-Lymphocytes
Disease-Free Survival
alemtuzumab
47 Citations (Scopus)

Preclinical targeting of aggressive T-cell malignancies using anti-CD5 chimeric antigen receptor

Chen, K. H., Wada, M., Pinz, K. G., Liu, H., Lin, K. W., Jares, A., Firor, A. E., Shuai, X., Salman, H. S., Golightly, M., Lan, F., Senzel, L., Leung, E. L., Jiang, X. & Ma, Y., Oct 1 2017, In : Leukemia. 31, 10, p. 2151-2160 10 p.

Research output: Contribution to journalArticle

CD5 Antigens
Antigen Receptors
Natural Killer Cells
T-Lymphocytes
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
11 Citations (Scopus)
Medullary Carcinoma
Ligands
Kidney
Mortality
Disease Progression
8 Citations (Scopus)

Promoter methylation modulates indoleamine 2,3-dioxygenase 1 induction by activated T cells in human breast cancers

Noonepalle, S. K., Gu, F., Lee, E. J., Choi, J. H., Han, Q., Kim, J., Ouzounova, M., Shull, A. Y., Pei, L., Hsu, P. Y., Kolhe, R., Shi, F., Choi, J., Chiou, K., Huang, T. H. M., Korkaya, H., Deng, L., Xin, H. B., Huang, S., Thangaraju, M. & 5 others, Sreekumar, A., Ambs, S., Tang, S. C., Munn, D. H. & Shi, H., Apr 2017, In : Cancer Immunology Research. 5, 4, p. 330-344 15 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Methylation
Triple Negative Breast Neoplasms
Breast Neoplasms
T-Lymphocytes
31 Citations (Scopus)

Protein Nanocage Mediated Fibroblast-Activation Protein Targeted Photoimmunotherapy to Enhance Cytotoxic T Cell Infiltration and Tumor Control

Zhen, Z., Tang, W., Wang, M., Zhou, S., Wang, H., Wu, Z., Hao, Z., Li, Z., Liu, L. & Xie, J., Feb 8 2017, In : Nano Letters. 17, 2, p. 862-869 8 p.

Research output: Contribution to journalArticle

T-cells
fibroblasts
infiltration
Fibroblasts
Infiltration
25 Citations (Scopus)

Recent trends in racial and regional disparities in cervical cancer incidence and mortality in United States

Yoo, W., Kim, S., Huh, W. K., Dilley, S., Coughlin, S. S., Partridge, E. E., Chung, Y., Dicks, V., Lee, J. K. & Bae, S., Feb 2017, In : PloS one. 12, 2, e0172548.

Research output: Contribution to journalArticle

Epidemiology
uterine cervical neoplasms
Uterine Cervical Neoplasms
Screening
incidence
4 Citations (Scopus)

RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins

Chen, F., Wang, Y., Rafikov, R., Haigh, S., Kumar, S., Rafikova, O., Lucas, R., Verin, A. D., Black, S. M. & Fulton, D. J. R., Mar 1 2017, In : Biochemical Pharmacology. 127, p. 34-45 12 p.

Research output: Contribution to journalArticle

Bacterial Toxins
Nitric Oxide
glutathione-independent formaldehyde dehydrogenase
Lung
Calcium
20 Citations (Scopus)

SETD1B activates iNOS expression in myeloid-derived suppressor cells

Redd, P. S., Ibrahim, M. L., Klement, J. D., Sharman, S. K., Paschall, A. V., Yang, D., Nayak-Kapoor, A. & Liu, K., Jun 1 2017, In : Cancer Research. 77, 11, p. 2834-2843 10 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type II
Neoplasms
Myeloid Cells
Nitric Oxide
Myeloid-Derived Suppressor Cells
19 Citations (Scopus)

Sildenafil suppresses inflammation-driven colorectal cancer in mice

Islam, B. N., Sharman, S. K., Hou, Y., Bridges, A. E., Singh, N., Kim, S., Kolhe, R. B., Trillo-Tinoco, J., Rodriguez, P. C., Berger, F. G., Sridhar, S. & Browning, D. D., Jul 1 2017, In : Cancer Prevention Research. 10, 7, p. 377-388 12 p.

Research output: Contribution to journalArticle

Polyps
Colorectal Neoplasms
Dextran Sulfate
Azoxymethane
Inflammation

Single-, low-dose cyclophosphamideassociated severe hyponatremia with seizures in a patient with breast cancer

Gandhi, A. S., Mensah, F., Titus, L., Bradley, A., Schlafstein, A. & Tang, S. C., Jan 1 2017, In : Journal of Community and Supportive Oncology. 15, 1, p. 37-39 3 p.

Research output: Contribution to journalArticle

Hyponatremia
Seizures
Breast Neoplasms
4 Citations (Scopus)

Systemic levels of estrogens and PGE2 synthesis in relation to postmenopausal breast cancer risk

Kim, S., Campbell, J., Yoo, W., Taylor, J. A. & Sandler, D. P., Mar 1 2017, In : Cancer Epidemiology Biomarkers and Prevention. 26, 3, p. 383-388 6 p.

Research output: Contribution to journalArticle

Dinoprostone
Estrogens
Breast Neoplasms
Confidence Intervals
Aromatase
13 Citations (Scopus)

Targeting T-cell malignancies using anti-CD4 CAR NK-92 cells

Pinz, K. G., Yakaboski, E., Jares, A., Liu, H., Firor, A. E., Chen, K. H., Wada, M., Salman, H. S., Tse, W., Hagag, N., Lan, F., Leung, E. L. H., Jiang, X. & Ma, Y., Jan 1 2017, In : Oncotarget. 8, 68, p. 112783-112796 14 p.

Research output: Contribution to journalArticle

CD4 Antigens
Antigen Receptors
Peripheral T-Cell Lymphoma
Natural Killer Cells
T-Lymphocytes
14 Citations (Scopus)

The impact of antibiotic usage on the efficacy of chemoimmunotherapy is contingent on the source of tumorreactive T cells

Kuczma, M. P., Ding, Z-C., Li, T., Habtetsion, T., Chen, T., Hao, Z., Bryan, L. J., Singh, N., Kochenderfer, J. N. & Zhou, G., Jan 1 2017, In : Oncotarget. 8, 67, p. 111931-111942 12 p.

Research output: Contribution to journalArticle

Anti-Bacterial Agents
T-Lymphocytes
Cell- and Tissue-Based Therapy
Antibiotic Prophylaxis
B-Cell Lymphoma
3 Citations (Scopus)

The safety of Bosutinib for the treatment of chronic myeloid leukemia

Kong, J. H., Khoury, H., Kim, A. S., Hill, B. G. & Kota, V., Oct 3 2017, In : Expert Opinion on Drug Safety. 16, 10, p. 1203-1209 7 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Protein-Tyrosine Kinases
Safety
Leukemia, Myeloid, Chronic Phase
Therapeutics

Unusual Contiguous Soft Tissue Spread of Advanced Malignant Mesothelioma Detected by FDG PET/CT

Zhang, Y., Edwards, J., Williams, H. T., Hao, Z., Khleif, S. N. & Pucar, D., Jun 1 2017, In : Nuclear Medicine and Molecular Imaging. 51, 2, p. 178-181 4 p.

Research output: Contribution to journalArticle

Neoplasms
Thorax
Serous Membrane
Pleura
Peritoneum
44 Citations (Scopus)

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci

Canver, M. C., Lessard, S., Pinello, L., Wu, Y., Ilboudo, Y., Stern, E. N., Needleman, A. J., Galactéros, F., Brugnara, C., Kutlar, A., McKenzie, C., Reid, M., Chen, D. D., Das, P. P., A Cole, M., Zeng, J., Kurita, R., Nakamura, Y., Yuan, G. C., Lettre, G. & 2 others, Bauer, D. E. & Orkin, S. H., Mar 30 2017, In : Nature Genetics. 49, 4, p. 625-634 10 p.

Research output: Contribution to journalArticle

Mutagenesis
Libraries
Fetal Hemoglobin
Intergenic DNA
Genome-Wide Association Study
1 Citation (Scopus)

Vessel morphometric parameters-correlation with histologic grade and VEGF expression in oligodendroglioma

Strickland-Marmol, L. B., Brem, S., Rojiani, A. M. & Rojiani, M. V., Jan 1 2017, In : American Journal of Cancer Research. 7, 4, p. 973-981 9 p.

Research output: Contribution to journalArticle

Oligodendroglioma
Vascular Endothelial Growth Factor A
Neoplasms
Blood Vessels
Microvessels
2016
3 Citations (Scopus)

B7-H3 upregulates BRCC3 expression, antagonizing DNA damage caused by 5-Fu

Sun, Z. Z., Zhang, T., Ning, K., Zhu, R., Liu, F., Tang, S-C., Jiang, B. & Hua, D., Jul 2016, In : Oncology Reports. 36, 1, p. 231-238 8 p.

Research output: Contribution to journalArticle

Fluorouracil
DNA Damage
Up-Regulation
Colorectal Neoplasms
DNA Repair
2 Citations (Scopus)

Battling regional (stage III) lung cancer: Bumpy road of a cancer survivor in the immunotherapy age

Hao, Z., Biddinger, P., Schroeder, C. & Tariq, K., Jan 1 2016, In : BMJ Case Reports. 2016, 215304.

Research output: Contribution to journalArticle

docetaxel
Immunotherapy
Survivors
Lung Neoplasms
Kidney
13 Citations (Scopus)

CD133+CD24lo defines a 5-Fluorouracil-resistant colon cancer stem cell-like phenotype

Paschall, A. V., Yang, D., Lu, C., Redd, P. S., Choi, J. H., Heaton, C. M., Lee, J. R., Nayak-Kapoor, A. & Liu, K., Jan 1 2016, In : Oncotarget. 7, 48, p. 78698-78712 15 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Fluorouracil
Colonic Neoplasms
Phenotype
Gene Expression