Hematology and Oncology

Research Output 1963 2019

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1989
9 Citations (Scopus)

HB brockton [α2β2138(h16)ALA→PRO] observed in a turkish girl

Ulukutlu, L., Ozsahin, H., Wilson, J. B., Webber, B. B., Hu, H., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 5, p. 509-513 5 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Abnormal Hemoglobins
Protein Denaturation
Peptide Fragments
Turkey
9 Citations (Scopus)

HB Chandigarh or α2β294(FGl)ASP→GLY observed in an indian family

Dash, S., Webber, B. B., Kutlar, A., Huisman, T. H. J. & Wilson, J. B., Jan 1 1989, In : Hemoglobin. 13, 7-8, p. 749-752 4 p.

Research output: Contribution to journalArticle

Abnormal Hemoglobins
13 Citations (Scopus)

Hb evans or α262(e11)val→metβ2; an unstable hemoglobin causing a mild hemolytic anemia

Wilson, J. B., Webber, B. B., Kutlar, A., Reese, A. L., Mckie, V. C., Lutcher, C. L., Felice, A. E. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 6, p. 557-566 10 p.

Research output: Contribution to journalArticle

Hemolytic Anemia
Heme
Hemoglobins
Mutation
Globins
12 Citations (Scopus)

HB extremadura or α2β2133(h11)VAU→LEU, a new mildly unstable hemoglobin in a Spanish female

Villegas, A., Martín, G., Wilson, J. B., Webber, B. B., Hu, H., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 5, p. 505-508 4 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Abnormal Hemoglobins
Valine
Leucine
Spain
10 Citations (Scopus)

HB f-h-Osaka or (α2gγ;263(e7)HIS→TYR in a caucasian male infant

Glader, B. E., Zwerdling, D., Kutlar, F., Kutlar, A., Wilson, J. B. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 7-8, p. 769-773 5 p.

Research output: Contribution to journalArticle

Hemoglobin M
Abnormal Hemoglobins
Fetal Hemoglobin
5 Citations (Scopus)

Hb gainesville-ga or α2β246(cd5) gly→arg; second report

Wilson, J. B., Webber, B. B., Kutlar, A. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 6, p. 623-624 2 p.

Research output: Contribution to journalArticle

Blood Protein Electrophoresis
Abnormal Hemoglobins
Hemoglobin A
Fetal Hemoglobin
High Pressure Liquid Chromatography
10 Citations (Scopus)

Hb Himeji or α2β2140(h18)ala→asp in a portuguese family

Martins, M. C., Rosado, L., Wilson, J. B., Kutlar, A., Hu, H. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 4, p. 411-415 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

HB j-Lome or α2β259(e3)LYS→ASN in a vietnamese family

Prior, J. F., Raven, J. L., Wilson, J. B., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 1, p. 79-81 3 p.

Research output: Contribution to journalArticle

Hemoglobin J
Abnormal Hemoglobins
31 Citations (Scopus)

HB monroe or α2β230(b12)ARG→THR, a variant associated with βthalassemia due to a g→c substitution adjacent to the donor splice site of the first intron

Gonzalez-Redondo, J. M., Stoming, T. A., Kutlar, F., Kutlar, A., Hu, H., Wilson, J. B. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Abnormal Hemoglobins
RNA Splice Sites
Thalassemia
Gene Rearrangement
14 Citations (Scopus)

Hydrops fetalis due to homozygosity for α-thalassemia-1, -(α)-20.5 kb: The first observation in a Turkish family

Gurgey, A., Altay, Beksaç, M. S., Bhattacharya, R., Kutlar, F. & Huisman, T. H. J., Jan 1 1989, In : Acta Haematologica. 81, 3, p. 169-171 3 p.

Research output: Contribution to journalArticle

Hydrops Fetalis
Thalassemia
Globins
Chromosome Mapping
Fetus
7 Citations (Scopus)

Mechanisms for the stimulation of prostanoid synthesis by cyclosporine and bacterial lipopolysacch aride

Zhang, H., Kaseki, H., Davis, W. B., Whisler, R. L. & Cornwell, D. G., Jan 1 1989, In : Transplantation. 47, 5, p. 864-871 8 p.

Research output: Contribution to journalArticle

Arachidonic Acid
Cyclosporine
Prostaglandins
Calcimycin
Prostaglandin-Endoperoxide Synthases
84 Citations (Scopus)

Molecular characterization of β‐globin gene mutations in Malay patients with Hb E‐β‐thalassaemia and thalassaemia major

Yang, K. G., Kutlar, F., George, E., Wilson, J. B., Kutlar, A., Stoming, T. A., Redondo, J. M. G. & Huisman, T. H. J., Jan 1 1989, In : British Journal of Haematology. 72, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

Globins
beta-Thalassemia
Codon
Thalassemia
Mutation
20 Citations (Scopus)

Molecular heterogeneity of beta-thalassemia intermedia in turkey

Gurgey, A., Altay, Diaz-Chico, J. C., Kutlar, F., Kutlar, A. & Huisman, T. H. J., Jan 1 1989, In : Acta Haematologica. 81, 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

beta-Thalassemia
Thalassemia
Codon
Mutation
Genetic Association Studies
19 Citations (Scopus)

Normal Fetal Hemoglobin Levels in the Sudden Infant Death Syndrome

Zielke, H. R., Meny, R. G., O'brien, M. J., Smialek, J. E., Kutlar, F., Huisman, T. H. J. & Dover, G. J., Nov 16 1989, In : New England Journal of Medicine. 321, 20, p. 1359-1364 6 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Sudden Infant Death
Fluorescent Antibody Technique
Cause of Death
Parents
12 Citations (Scopus)

Quantitation of hemoglobins Bart's, H, Portland-I, Portland-II and constant spring by anion-exchange high-performance liquid chromatography

Kutlar, F., Gu, L. H., Hu, H. & Huisman, T. H. J., Jan 1 1989, In : Journal of Chromatography B: Biomedical Sciences and Applications. 487, C, p. 265-274 10 p.

Research output: Contribution to journalArticle

Hemoglobin H
High performance liquid chromatography
Anions
Blood
Abnormal Hemoglobins
41 Citations (Scopus)

Severe Hb S-β°-thalassaemia with a T→C substitution in the donor splice site of the first intron of the β-globin gene

Gonzalez-Redondo, J. M., Stoming, T. A., Kutlar, F., Kutlar, A., McKie, V. C., McKie, K. M. & Huisman, T. H. J., Jan 1 1989, In : British Journal of Haematology. 71, 1, p. 113-117 5 p.

Research output: Contribution to journalArticle

RNA Splice Sites
Thalassemia
Globins
Introns
Genes
17 Citations (Scopus)

Studies on oxidized low density lipoproteins. Controlled oxidation and a prostaglandin artifact

Zhang, H., Davis, W. B., Chen, X., Whisler, R. L. & Cornwell, D. G., Jan 1 1989, In : Journal of Lipid Research. 30, 2, p. 141-148 8 p.

Research output: Contribution to journalArticle

LDL Lipoproteins
Artifacts
Prostaglandins
Lipoproteins
Oxidation
32 Citations (Scopus)

The levels of ζ, γ, and δ chains in patients with Hb H disease

Kutlar, F., Gonzalez-Redondo, J. M., Kutlar, A., Gurgey, A., Altay, Ç., Efremov, G. D., Kleman, K. & Huisman, T. H. J., May 1 1989, In : Human Genetics. 82, 2, p. 179-186 8 p.

Research output: Contribution to journalArticle

RNA Splice Sites
Globins
Far East
Hemolytic Anemia
Gene Deletion
14 Citations (Scopus)

The types of hemoglobins and globin chains in hydrops fetalis

Kutlar, F., Reese, A. L., Hsia, Y. E., Kleman, K. M. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 7-8, p. 671-683 13 p.

Research output: Contribution to journalArticle

Hydrops Fetalis
Globins
Hemoglobins
Cells
Blood
6 Citations (Scopus)

Two rare unstable β chain variants, HB mozhaisk or α2β292(f8)his ARG and HB DJELFA or α2β298(FG5)VAL→ALA, each being observed for the second time

Bird, A. R., Elliott, T., Wison, J. B., Webber, B. B., Hu, H., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 2, p. 193-197 5 p.

Research output: Contribution to journalArticle

Cellulose Acetate Electrophoresis
Abnormal Hemoglobins
Amino Acid Sequence
High Pressure Liquid Chromatography

α‐thalassemia among Pediatric Hemoglobin S Homozygotes: Molecular and Clinical Studies

FELICE, A. E., ZHAO, J., Kutlar, A., RHODES, M., McKie, K. & McKie, V., Jan 1 1989, In : Annals of the New York Academy of Sciences. 565, 1, p. 381-382 2 p.

Research output: Contribution to journalArticle

Sickle Hemoglobin
alpha-Thalassemia
Homozygote
Pediatrics
Clinical Studies
18 Citations (Scopus)

βthalassemia intermedia in two turkish families is caused by the interaction of HB knossos [β27(b9)ALA→SER] and of HB city of Hope [β69(e13)gly→ser] with b°thalassemia

Kutlar, A., Kutlar, F., Aksoy, M., Gurgey, A., Altay, C., Wilson, J. B., Diaz-Chico, J. C., Hu, H. & Huisman, T. H. J., Jan 1 1989, In : Hemoglobin. 13, 1, p. 7-16 10 p.

Research output: Contribution to journalArticle

Thalassemia
beta-Thalassemia
Abnormal Hemoglobins
Oligonucleotide Probes
High performance liquid chromatography
1988
7 Citations (Scopus)

A chromosome with five γ-globin genes

Fei, Y. J., Lanclos Ke., D., Kutlar, F., Walker, E. F. & Huisman, T. H. J., Jan 1 1988, In : Blood. 72, 2, p. 827-829 3 p.

Research output: Contribution to journalArticle

Globins
Chromosomes
Genes
Fetal Hemoglobin
Chromosome Mapping
13 Citations (Scopus)

Biochemical and molecular aspects of βthalassemia types in northern sardinia

Masala, B., Manca, L., Gallisai, D., Stangoni, A., Lanclos, K. D., Kutlar, F., Yang, K. G. & Huisnan, T. H. J., Jan 1 1988, In : Hemoglobin. 12, 5-6, p. 661-671 11 p.

Research output: Contribution to journalArticle

Thalassemia
Haplotypes
Italy
Chromosomes
Genes
8 Citations (Scopus)

Characterization of abnormalities in the γglobin gene arrangements of japanese newborns

Harano, T., Harano, K., Ukita, H., Wada, Y., Hayashi, A., Ohba, Y., Miyaji, T., Kutlar, F. & Huisman, T. H. J., Jan 1 1988, In : Hemoglobin. 12, 5-6, p. 723-739 17 p.

Research output: Contribution to journalArticle

Gene Order
Globins
Genes
Newborn Infant
Chromosomes
145 Citations (Scopus)

Clinical and genetic heterogeneity in black patients with homozygous β-thalassemia from the Southeastern United States

Gonzalez-Redondo, J. M., Stoming, T. A., Lanclos, K. D., Gu, Y. C., Kutlar, A., Nakatsuji, T., Deng, B., Han, I. S., McKie, V. C. & Huisman, T. H. J., Jan 1 1988, In : Blood. 72, 3, p. 1007-1014 8 p.

Research output: Contribution to journalArticle

Southeastern United States
Thalassemia
Genetic Heterogeneity
Fetal Hemoglobin
Chromosomes
9 Citations (Scopus)

HB duan [α75(EF4)ASP→ALA), HB Westmead [α122(h5)HIS→GLN], and αthalassemia-2 (-4.2 KB deletion) in a chinese family

Liang, S., Tang, Z., Su, C., Lung, Q., Liang, R., Fei, Y. J., Kutlar, F., Wilson, J. B., Mebber, B. B., Hu, H. & Huisman, T. H. J., Jan 1 1988, In : Hemoglobin. 12, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

Thalassemia
Globins
Chromosomes
Substitution reactions
Genes
11 Citations (Scopus)

Hb las palms or α2β249(cd8)ser→phe, a mildly unstable hemiglobin variant

Malcorra-Azpiazu, J. J., Balda-Aguirre, H. I., Diaz-Chico, J. C., Hu, H., Wilson, J. B., Webber, B. B., Kutlar, F., Kutlar, A. & Huisman, T. H. J., Jan 1 1988, In : Hemoglobin. 12, 2, p. 163-170 8 p.

Research output: Contribution to journalArticle

High performance liquid chromatography
Electrophoresis
Spain
Hemoglobins
Substitution reactions
13 Citations (Scopus)

Hb Natal or α2(minus Tyr-Arg)β2: A high oxygen affinity α chain variant with a deleted carboxy-terminus resulting from a TAC → TAA (Tyr → terminating codon) mutation in codon α140

Jogessar, V. B., Westermeyer, K., Webber, B. B., Wilson, J. B., Hu, H., Gonzalez-Redondo, J. M., Kutlar, A. & Huisman, T. H. J., Nov 10 1988, In : BBA - Gene Structure and Expression. 951, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

kyotorphin
Heme
Codon
Tyrosine
Oxygen
23 Citations (Scopus)

Hb S(c)-β+ -thalassaemia: Different mutations are associated with different levels of normal Hb A

Gonzalez-Redondo, J. M., Kutlar, F., Kutlar, A., Stoming, T. A., De Pablos, J. M., Kilinc, Y. & Huisman, T. H. J., Jan 1 1988, In : British Journal of Haematology. 70, 1, p. 85-89 5 p.

Research output: Contribution to journalArticle

Thalassemia
Mutation
Globins
Oligonucleotide Probes
Hematology
51 Citations (Scopus)

Inclusion body β-thalassemia trait in a Swiss family is caused by an abnormal hemoglobin (Geneva) with an altered and extended β chain carboxy-terminus due to a modification in codon β114

Beris, P., Miescher, P. A., Diaz-Chico, J. C., Han, I. S., Kutlar, A., Hu, H., Wilson, J. B. & Huisman, T. H. J., Jan 1 1988, In : Blood. 72, 2, p. 801-805 5 p.

Research output: Contribution to journalArticle

Abnormal Hemoglobins
Thalassemia
Inclusion Bodies
Codon
Cells
83 Citations (Scopus)

Mild and severe β-thalassemia among homozygotes from Turkey: Identification of the types by hybridization of amplified DNA with synthetic probes

Diaz-Chico, J. C., Yang, K. G., Stoming, T. A., Efremov, D. G., Kutlar, A., Kutlar, F., Aksoy, M., Altay, C., Gurgey, A., Kilinc, Y. & Huisman, T. H. J., Jan 1 1988, In : Blood. 71, 1, p. 248-251 4 p.

Research output: Contribution to journalArticle

Thalassemia
Homozygote
Turkey
Nucleotides
DNA
10 Citations (Scopus)

Quantification of hemoglobins S, C, and F by a magnetic affinity immunoassay

Moscoso, H., Kiefer, C. R., Kutlar, A. & Garver, F. A., Jan 1 1988, In : Clinical Chemistry. 34, 5, p. 902-905 4 p.

Research output: Contribution to journalArticle

Hemoglobin C
Sickle Hemoglobin
Fetal Hemoglobin
Immunoassay
Hemoglobins
16 Citations (Scopus)

Some rare hemoglobin variants with altered oxygen affinities; hb linkoping [β36(c2)pro→thr], hb caribbean [β91(f7)leu→ar6], and hb sunnybrook [β 36(c2)pro→arg]

Ali, M. A. M., Pinkerton, P., Chow, S. W. S., Zaetz, S. D., Wilson, J. B., Webber, B. B., Hu, H., Kutlar, F. & Huisman, T. H. J., Jan 1 1988, In : Hemoglobin. 12, 2, p. 137-148 12 p.

Research output: Contribution to journalArticle

Hemoglobins
Oxygen
Polycythemia
Anemia
Liquids
21 Citations (Scopus)
Membrane Glycoproteins
Cellular Structures
Platelets
Fatty Acids
Blood Platelets
20 Citations (Scopus)
Glycoproteins
Binding Sites
Monoclonal Antibodies
Membranes
Peptides
28 Citations (Scopus)

Upstream promoter mutation associated with a modest elevation of fetal hemoglobin expression in human adults

Gilman, J. G., Mishima, N., Wen, X. J., Kutlar, F. & Huisman, T. H. J., Jan 1 1988, In : Blood. 72, 1, p. 78-81 4 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Haplotypes
Genes
Mutation
Benin
27 Citations (Scopus)

Variation in clinical severity among patients with Hb Lepore-Boston-β-thalassaemia is related to the type of β-thalassaemia

Efremov, D. G., Efremov, G. D., Zisovski, N., Stojanovski, N., Kutlar, F., Diaz-Chico, J. C., Kutlar, A., Yang, K. G., Stoming, T. A. & Huisman, T. H. J., Jan 1 1988, In : British Journal of Haematology. 68, 3, p. 351-355 5 p.

Research output: Contribution to journalArticle

Thalassemia
Blood Transfusion
Globins
Codon
hemoglobin Lepore Boston
7 Citations (Scopus)

Variations in gγ, and aγ ratios in the fetal hemiglobin of newborn babies

Huisman, T. H. J., Fei, Y. J. & Kutlar, F., Jan 1 1988, In : Hemoglobin. 12, 5-6, p. 699-705 7 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Globins
1987
10 Citations (Scopus)

Adult hemoglobin levels in newborn babies from different countries and in babies with some significant hemoglobinopathies

Kutlar, F., Kutlar, A., Gu, Y. C. & Huisman, T. H. J., Jan 1 1987, In : Acta Haematologica. 78, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

Hemoglobinopathies
Globins
Hemoglobins
Thalassemia
Fetal Blood
12 Citations (Scopus)

A G to A nucleotide substitution 161 base pairs 5' of the G gamma globin gene cap site (-161) in a high G gamma non-anemic person.

Gilman, J. G., Kutlar, F., Johnson, M. E. & Huisman, T. H., Jan 1 1987, In : Progress in Clinical and Biological Research. 251, p. 383-390 8 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
RNA Caps
gamma-Globins
Fetal Hemoglobin
Globins
30 Citations (Scopus)

An ~300 bp deletion involving part of the 5' β-globin gene region is observed in members of a Turkish family with β-thalassemia

Diaz-Chico, J. C., Yang, K. G., Kutlar, A., Reese, A. L., Aksoy, M. & Huisman, T. H. J., Jan 1 1987, In : Blood. 70, 2, p. 583-586 4 p.

Research output: Contribution to journalArticle

Thalassemia
Globins
Hemoglobin A2
Genes
Chromosome Mapping
1 Citation (Scopus)

An indonesian family with the southeast asian type of α-thalassemia-1 and a γ-globin gene triplication

Daenen, S., Reese, A. L., Kutlar, F. & Huisman, T., Jan 1 1987, In : Acta Haematologica. 78, 1, p. 23-27 5 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Thalassemia
Globins
Chromosome Mapping
Genes
21 Citations (Scopus)

Characterization of chromosomes with hybrid genes for Hb Lepore-Washington, Hb Lepore-Baltimore, Hb P-Nilotic, and Hb Kenya

Lanclos, K. D., Patterson, J., Efremov, G. D., Wong, S. C., Villegas, A., Ojwang, P. J., Wilson, J. B., Kutlar, F. & Huisman, T. H. J., Jan 1 1987, In : Human Genetics. 77, 1, p. 40-45 6 p.

Research output: Contribution to journalArticle

Chromosomes
Haplotypes
Genes
Chromosomes, Human, Pair 8
Chromosomes, Human, Pair 5
18 Citations (Scopus)

Detection of the embryonic ζ chain in blood from newborn babies by reversed-phase high-perfomance liquid chromatogrphy

Kutlar, F., Fei, Y. J., Wilson, J. B., Kutlar, A. & Huisman, T. H. J., Jan 1 1987, In : Journal of Chromatography A. 394, 2, p. 333-343 11 p.

Research output: Contribution to journalArticle

Globins
Blood
Thalassemia
Genes
High performance liquid chromatography
18 Citations (Scopus)

Effects of α‐thalassemia‐2 on the developmental changes of hematological values in children with sickle cell disease from georgia

Felice, A. E., McKie, K. M., Cleek, M. P., Marino, E. M., Kutlar, A. & McKie, V. C., Jan 1 1987, In : American Journal of Hematology. 25, 4, p. 389-400 12 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Sickle Cell Anemia
Globins
Sickle Hemoglobin
Erythrocyte Indices
4 Citations (Scopus)

Fetal hemoglobin heterogeneity in chinese newborns of the uygur and han nationalities; comparisons of babies from xinjiang and Beijing

Chu, Z. F., Liang, C. C., Kutlar, F. & Huisman, T. H. J., Jan 1 1987, In : Hemoglobin. 11, 2, p. 123-128 6 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Chromosome Mapping
Ethnic Groups
Restriction Fragment Length Polymorphisms
China
42 Citations (Scopus)

Haplotypes and α globin gene analyses in sickle cell anaemia patients from Kenya

Ojwang, P. J., Ogada, T., Beris, P., Hattori, Y., Lanclos, K. D., Kutlar, A., Kutlar, F. & Huisman, T. H. J., Jan 1 1987, In : British Journal of Haematology. 65, 2, p. 211-215 5 p.

Research output: Contribution to journalArticle

Globins
Kenya
Sickle Cell Anemia
Haplotypes
Genes
1 Citation (Scopus)

Hb borås or α2β288(f4)leu → arg in a south african female

Bird, A. R., Elliot, T. E., Wilson, J. B., Webber, B. B., Kutlar, F., Kutlar, A. & Huisman, T. H. J., Jan 1 1987, In : Hemoglobin. 11, 2, p. 157-160 4 p.

Research output: Contribution to journalArticle

High pressure liquid chromatography
Abnormal Hemoglobins
Leucine
Arginine
hemoglobin Boras
3 Citations (Scopus)

Hb bushwick [β74(e18)GLY→VAL] heterozygotes in a yugoslavian family have 35 to 40% of the unstable variant

Efremov, G. D., Jankovic, L., Juricic, D., Stojancov, A., Wilson, J. B., Webber, B. B., Kutlar, F., Kutlar, A., Hu, H. & Huisman, T. H. J., Jan 1 1987, In : Hemoglobin. 11, 6, p. 557-562 6 p.

Research output: Contribution to journalArticle

Congenital Hemolytic Anemia
Abnormal Hemoglobins
Heterozygote
Electrophoresis
Chromatography