Hematology and Oncology

Research Output 1963 2019

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2015
48 Citations (Scopus)

Suppression of tumor angiogenesis by metformin treatment via a mechanism linked to targeting of HER2/HIF-1α/VEGF secretion axis

Wang, J., Li, G., Wang, Y., Tang, S-C., Sun, X., Feng, X., Li, Y., Bao, G., Li, P., Mao, X., Wang, M. & Liu, P., Jan 1 2015, In : Oncotarget. 6, 42, p. 44579-44592 14 p.

Research output: Contribution to journalArticle

Metformin
Vascular Endothelial Growth Factor A
Neoplasms
Neuregulin-1
Microvessels
3 Citations (Scopus)

The FDA Guidance on therapeutic cancer vaccines: The need for revision to include preventive cancer vaccines or for anewguidance dedicated to them

Finn, O. J., Khleif, S. N. & Herberman, R. B., Nov 1 2015, In : Cancer Prevention Research. 8, 11, p. 1011-1016 6 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Vaccines
Therapeutics
Disease Progression
Immune System
13 Citations (Scopus)

The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60

Cui, H., Guo, M., Xu, D., Ding, Z-C., Zhou, G., Ding, H., Zhang, J., Tang, Y. & Yan, C., Apr 13 2015, In : Nature Communications. 6, 6752.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
tat Gene Products
Histone Acetyltransferases
genes
Genes
7 Citations (Scopus)

Thyroid transcription factor-1 expression is significantly associated with mutations in exon 21 of the epidermal growth factor receptor gene in Chinese patients with lung adenocarcinoma

Zhao, Q., Xu, S., Liu, J., Li, Y., Fan, Y., Shi, T., Wei, S., Tang, S-C., Liu, H. & Chen, J., Sep 7 2015, In : OncoTargets and Therapy. 8, p. 2469-2478 10 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Exons
Epidermal Growth Factor Receptor
Mutation
thyroid nuclear factor 1
16 Citations (Scopus)

TIMP-1 Inhibits apoptosis in lung adenocarcinoma cells via interaction with Bcl-2

Nalluri, S., Ghoshal-Gupta, S., Kutiyanawalla, A., Gayatri, S., Lee, B. R., Jiwani, S., Rojiani, A. M. & Rojiani, M. V., Sep 14 2015, In : PLoS One. 10, 9, e0137673.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-1
metalloproteinases
adenocarcinoma
Cell Communication
apoptosis
17 Citations (Scopus)

TIMP-1 overexpression in lung carcinoma enhances tumor kinetics and angiogenesis in brain metastasis

Rojiani, M. V., Ghoshal-Gupta, S., Kutiyanawalla, A., Mathur, S. & Rojiani, A. M., Jan 1 2015, In : Journal of Neuropathology and Experimental Neurology. 74, 4, p. 293-304 12 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinases
Matrix Metalloproteinase 1
Tissue Inhibitor of Metalloproteinase-1
Neoplasm Metastasis
Carcinoma
4 Citations (Scopus)

Tumor Lysis Syndrome in Metastatic Colon Cancer Following Treatment with Regorafenib

Farooqi, B., Simmons, J. & Hao, Z., Oct 1 2015, In : Journal of Gastrointestinal Cancer. 46, 3, p. 314-316 3 p.

Research output: Contribution to journalArticle

Phenylurea Compounds
Tumor Lysis Syndrome
Pyridines
Colonic Neoplasms
Neoplasm Metastasis
57 Citations (Scopus)

Vps4A functions as a tumor suppressor by regulating the secretion and uptake of exosomal microRNAs in human hepatoma cells

Wei, J. X., Lv, L. H., Wan, Y. L., Cao, Y., Li, G. L., Lin, H. M., Zhou, R., Shang, C. Z., Cao, J., He, H., Han, Q. F., Liu, P. Q., Zhou, G. & Min, J., Apr 1 2015, In : Hepatology. 61, 4, p. 1284-1294 11 p.

Research output: Contribution to journalArticle

Exosomes
MicroRNAs
Hepatocellular Carcinoma
Neoplasms
Phosphatidylinositol 3-Kinase
2 Citations (Scopus)

Zoledronate can promote apoptosis and inhibit the proliferation of colorectal cancer cells

Gao, X., Jiang, B., Zou, S., Zhang, T., Qi, X., Jin, L., Ge, X., Tang, S. C., Hua, D. & Chen, W., Jul 29 2015, In : Tumor Biology. 36, 7, p. 5315-5322 8 p.

Research output: Contribution to journalArticle

zoledronic acid
Colorectal Neoplasms
Apoptosis
Mitochondria
Caco-2 Cells
2014
1 Citation (Scopus)

Acute facial paralysis and otomastoiditis as presenting symptoms of myeloid sarcoma

Howell, J., Segel, J., Jajosky, R., Savage, N. M., Fields, B., Kota, V. & Mowry, S., Aug 19 2014, (Accepted/In press) In : Otology and Neurotology.

Research output: Contribution to journalArticle

Mastoiditis
Myeloid Sarcoma
Second Primary Neoplasms
Facial Paralysis
Acute Myeloid Leukemia
33 Citations (Scopus)

A double-blind, placebo-controlled phase II study of the efficacy and safety of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease

Reid, M. E., El Beshlawy, A., Inati, A., Kutlar, A., Abboud, M. R., Haynes, J., Ward, R., Sharon, B., Taher, A. T., Smith, W., Manwani, D. & Ghalie, R. G., Jan 1 2014, In : American Journal of Hematology. 89, 7, p. 709-713 5 p.

Research output: Contribution to journalArticle

2,2-dimethylbutyric acid
Globins
Sickle Cell Anemia
Placebos
Safety
5 Citations (Scopus)

Azacitidine as salvage therapy for acute myeloid leukemia in a severely ill patient

Powers, H. R., Bachar, M., Savage, N. M., Toscano, M. P. & Dainer, P. M., Jan 1 2014, In : Hematology Reports. 6, 3, p. 58-60 3 p., 5516.

Research output: Contribution to journalArticle

Azacitidine
Salvage Therapy
Acute Myeloid Leukemia
Myeloid Progenitor Cells
Remission Induction
5 Citations (Scopus)

Bifocal juvenile papillomatosis as a marker of breast cancer: A case report and review of the literature

Wang, T., Li, Y. Q., Liu, H., Fu, X. L. & Tang, S. C., Dec 1 2014, In : Oncology Letters. 8, 6, p. 2587-2590 4 p.

Research output: Contribution to journalArticle

Papilloma
Breast Neoplasms
Breast
Fibroadenoma
Cheese
4 Citations (Scopus)

CYP2C9 allelic variants and frequencies in a pediatric sickle cell disease cohort: Implications for NSAIDs pharmacotherapy

Jaja, C., Patel, N., Scott, S. A., Gibson, R. W. & Kutlar, A., Oct 1 2014, In : Clinical and Translational Science. 7, 5, p. 396-401 6 p.

Research output: Contribution to journalArticle

Drug therapy
Pediatrics
Sickle Cell Anemia
Anti-Inflammatory Agents
Drug Therapy
10 Citations (Scopus)

Difficult conversations: From diagnosis to death

Marcus, J. D. & Mott, F. E., Dec 1 2014, In : Ochsner Journal. 14, 4, p. 712-717 6 p.

Research output: Contribution to journalArticle

Communication
Motivational Interviewing
Physicians
Cognitive Therapy
Therapeutics
18 Citations (Scopus)

Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury

Aggarwal, S., Gross, C. M., Kumar, S., Dimitropoulou, C., Sharma, S., Gorshkov, B. A., Sridhar, S., Lu, Q., Bogatcheva, N. V., Jezierska-Drutel, A. J., Lucas, R., Verin, A. D., Catravas, J. D. & Black, S. M., Jan 1 2014, In : American journal of respiratory cell and molecular biology. 50, 3, p. 614-625 12 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Lung
Oxidative stress
Nitration
Vascular System Injuries
79 Citations (Scopus)

Endothelial PFKFB3 plays a critical role in angiogenesis

Xu, Y., An, X., Guo, X., Habtetsion, T. G., Wang, Y., Xu, X., Kandala, S., Li, Q., Li, H., Zhang, C., Caldwell, R. B., Fulton, D. J., Su, Y., Hoda, MD. N., Zhou, G., Wu, C. & Huo, Y., Jan 1 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 6, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Protein Isoforms
Glycolysis
Endothelial Cells
Lactic Acid
30 Citations (Scopus)

Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase

Sun, X., Kumar, S., Sharma, S., Aggarwal, S., Lu, Q., Gross, C., Rafikova, O., Lee, S. G., Dasarathy, S., Hou, Y., Meadows, M. L., Han, W., Su, Y., Fineman, J. R. & Black, S. M., Jan 1 2014, In : American journal of respiratory cell and molecular biology. 50, 6, p. 1084-1095 12 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Endothelial cells
Endothelin-1
Pulmonary Hypertension
Endothelial Cells
13 Citations (Scopus)

Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167

Rafikov, R., Kumar, S., Aggarwal, S., Hou, Y., Kangath, A., Pardo, D., Fineman, J. R. & Black, S. M., Feb 1 2014, In : Free Radical Biology and Medicine. 67, p. 255-264 10 p.

Research output: Contribution to journalArticle

Phosphorylation
Endothelin-1
Catalase
Serine
Protein Kinase C
5 Citations (Scopus)

Exercise capacity as an independent risk factor for adverse cardiovascular outcomes among nondiabetic and diabetic patients

Pierre-Louis, B., Guddati, A. K., Syed, M. K. H., Gorospe, V. E., Manguerra, M., Bagchi, C., Aronow, W. S. & Ahn, C., Feb 1 2014, In : Archives of Medical Science. 10, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

Exercise
Stroke
Myocardial Infarction
Myocardial Ischemia
Coronary Artery Disease
32 Citations (Scopus)

Heat shock protein 90 inhibitors prevent lps-induced endothelial barrier dysfunction by disrupting Rhoa signaling

Joshi, A. D., Dimitropoulou, C., Thangjam, G., Snead, C., Feldman, S., Barabutis, N., Fulton, D. J., Hou, Y., Kumar, S., Patel, V. S., Gorshkov, B. A., Verin, A. D., Black, S. M. & Catravas, J. D., Jan 1 2014, In : American journal of respiratory cell and molecular biology. 50, 1, p. 170-179 10 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
tanespimycin
Endothelial cells
Myosin Light Chains
Phosphorylation
55 Citations (Scopus)

Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor cd4 t-cell responses through the PD-1-PD-L1 axis

Ding, Z. C., Lu, X., Yu, M., Lemos, H., Huang, L., Chandler, P., Liu, K., Walters, M., Krasinski, A., Mack, M., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Jul 1 2014, In : Cancer Research. 74, 13, p. 3441-3453 13 p.

Research output: Contribution to journalArticle

Myeloid Cells
Immunosuppressive Agents
Cyclophosphamide
Drug Therapy
Adoptive Transfer
12 Citations (Scopus)

Long-term outcome of fludarabine-based reduced-intensity allogeneic hematopoietic cell transplantation for debilitating paroxysmal nocturnal hemoglobinuria

Pantin, J. M., Tian, X., Geller, N., Ramos, C., Cook, L., Cho, E., Scheinberg, P., Vasu, S., Khuu, H., Stroncek, D., Barrett, J., Young, N. S., Donohue, T. & Childs, R. W., Jan 1 2014, In : Biology of Blood and Marrow Transplantation. 20, 9, p. 1435-1439 5 p.

Research output: Contribution to journalArticle

Paroxysmal Hemoglobinuria
Cell Transplantation
Glycosylphosphatidylinositols
Antilymphocyte Serum
Granulocyte Colony-Stimulating Factor
13 Citations (Scopus)

Modulation of BAG-1 expression alters the sensitivity of breast cancer cells to tamoxifen

Liu, H., Lu, S., Gu, L., Gao, Y., Wang, T., Zhao, J., Rao, J., Chen, J., Hao, X. & Tang, S-C., Jan 1 2014, In : Cellular Physiology and Biochemistry. 33, 2, p. 365-374 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Breast Neoplasms
MCF-7 Cells
Protein Isoforms
Down-Regulation
17 Citations (Scopus)

Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding

Aggarwal, S., Gross, C. M., Rafikov, R., Kumar, S., Fineman, J. R., Ludewig, B., Jonigk, D. & Black, S. M., Mar 14 2014, In : Journal of Biological Chemistry. 289, 11, p. 7948-7961 14 p.

Research output: Contribution to journalArticle

Nitration
Cyclic GMP-Dependent Protein Kinases
Cyclic GMP
Tyrosine
Smooth Muscle Myocytes

Nondeletional α-Thalassemia (α2- IVS-1-116, A>G HBA2): An α2 gene point mutation detected in an african-american female for the first time

Dainer, P. M., Patel, N., Zhuang, L., Carmichael, H. & Kutlar, F., Jan 1 2014, In : Acta Haematologica. 132, 1, p. 22-23 2 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Hemoglobin A2
Abnormal Hemoglobins
alpha-Thalassemia
Point Mutation

Pemetrexed and communicating hydrocephalus

Son, C. O. & Mott, F. E., Jan 1 2014, In : Ochsner Journal. 14, 2, p. 292-294 3 p.

Research output: Contribution to journalArticle

Pemetrexed
Hydrocephalus
Platinum
Maintenance
Mesothelioma
29 Citations (Scopus)

PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins

Chen, F., Kumar, S., Yu, Y., Aggarwal, S., Gross, C., Wang, Y., Chakraborty, T., Verin, A. D., Catravas, J. D., Lucas, R., Black, S. M. & Fulton, D. J., Jul 14 2014, In : PloS one. 9, 7, e99823.

Research output: Contribution to journalArticle

Phosphorylation
Nitric Oxide Synthase Type III
phosphorylation
toxins
Endothelial cells
10 Citations (Scopus)

Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction

Czikora, I., Sridhar, S., Gorshkov, B. A., Alieva, I. B., Kasa, A., Gonzales, J. N., Potapenko, O., Siddaramappa, U. N., Pillich, H., Rick, F. G., Block, N. L., Verin, A. D., Chakraborty, T., Matthay, M. A., Schally, A. V. & Lucas, R., Jan 1 2014, In : Frontiers in Physiology. 5 JUL, 00259.

Research output: Contribution to journalArticle

Bacterial Toxins
Growth Hormone-Releasing Hormone
Cyclic AMP-Dependent Protein Kinases
Lung
Endothelial Cells
3 Citations (Scopus)

Protein engineering to develop a redox insensitive endothelial nitric oxide synthase

Rafikov, R., Kumar, S., Aggarwal, S., Pardo, D., Fonseca, F. V., Ransom, J., Rafikova, O., Chen, Q., Springer, M. L. & Black, S. M., Jan 1 2014, In : Redox Biology. 2, 1, p. 156-164 9 p.

Research output: Contribution to journalArticle

Protein Engineering
Nitric Oxide Synthase Type III
Oxidation-Reduction
Dimers
Endothelial cells

Rituximab therapy for factor II inhibitor in a patient with antiphospholipid antibody syndrome

Guddati, A. K. & Kuter, D. J., Jan 1 2014, In : Blood Coagulation and Fibrinolysis. 25, 3, p. 289-291 3 p.

Research output: Contribution to journalArticle

Antiphospholipid Syndrome
Hemorrhage
Partial Thromboplastin Time
Prothrombin Time
Therapeutics
34 Citations (Scopus)

Safety, efficacy, and pharmacokinetics/pharmacodynamics of daclizumab (anti-CD25) in patients with adult T-cell leukemia/lymphoma

Berkowitz, J. L., Janik, J. E., Stewart, D. M., Jaffe, E. S., Stetler-Stevenson, M., Shih, J. H., Fleisher, T. A., Turner, M., Urquhart, N. E., Wharfe, G. H., Figg, W. D., Peer, C. J., Goldman, C. K., Waldmann, T. A. & Morris, J. C., Dec 1 2014, In : Clinical Immunology. 155, 2, p. 176-187 12 p.

Research output: Contribution to journalArticle

Adult T Cell Leukemia Lymphoma
Pharmacokinetics
Safety
Interleukin-2 Receptors
Deltaretrovirus
52 Citations (Scopus)

Selective inhibition of regulatory T cells by targeting the PI3K-Akt pathway

Abu-Eid, R., Samara, R. N., Ozbun, L., Abdalla, M. Y., Berzofsky, J. A., Friedman, K. M., Mkrtichyan, M. & Khleif, S. N., Nov 1 2014, In : Cancer Immunology Research. 2, 11, p. 1080-1089 10 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Phosphatidylinositol 3-Kinases
Tumor Escape
T-Lymphocytes
Therapeutic Uses
5 Citations (Scopus)

Sox18 Preserves the Pulmonary Endothelial Barrier Under Conditions of Increased Shear Stress

Gross, C. M., Aggarwal, S., Kumar, S., Tian, J., Kasa, A., Bogatcheva, N., Datar, S. A., Verin, A. D., Fineman, J. R. & Black, S. M., Jan 1 2014, In : Journal of Cellular Physiology. 229, 11, p. 1802-1816 15 p.

Research output: Contribution to journalArticle

Claudin-5
Shear stress
Lung
Blood
Endothelial cells
35 Citations (Scopus)

The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation

Salazar, N., Muñoz, D., Kallifatidis, G., Singh, R. K., Jordà, M. & Lokeshwar, B. L., Aug 28 2014, In : Molecular cancer. 13, 1, 198.

Research output: Contribution to journalArticle

CXCR Receptors
Chemokine Receptors
Epidermal Growth Factor Receptor
Cell Proliferation
Breast Neoplasms
2 Citations (Scopus)

Two new hemoglobin variants: Hb tallahassee [α3(a1)ser→tyr; Hba2: C.11c>a] and hb madison-nc [β119(gh2)gly→ser; Hbb: C.358g>a]

Kutlar, F., Unguru, Y., Dixon, N., Patel, N., Bailey, L., Zhuang, L., Carmichael, H. & Kutlar, A., Jan 1 2014, In : Hemoglobin. 38, 3, p. 207-210 4 p.

Research output: Contribution to journalArticle

Globins
Hemoglobins
Codon
Phenotype
Screening
1 Citation (Scopus)

Two new γ chain variants: Hb F-Augusta GA [Gγ59(E3)Lys→Arg; HBG2: C.179A>G] and Hb F-Port Royal-II [Aγ125(H3)Glu→Ala; HBG1: C.377A>C]

Kutlar, F., Ameri, A., Patel, N. H., Zhuang, L., Johnson, L. E., Cheng, M. L. & Kutlar, A., Oct 1 2014, In : Hemoglobin. 38, 5, p. 376-380 5 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Globins
Molecular Pathology
African Americans
Screening
4 Citations (Scopus)

Vascular alterations in schwannoma

Papiez, J., Rojiani, M. V. & Rojiani, A. M., Jan 1 2014, In : International Journal of Clinical and Experimental Pathology. 7, 7, p. 4032-4038 7 p.

Research output: Contribution to journalArticle

Neurilemmoma
Blood Vessels
Neurofibroma
Meningioma
Hemosiderin
2013
12 Citations (Scopus)

A clinical investigation of inhibitory effect of panobinostat on CYP2D6 substrate in patients with advanced cancer

Feld, R., Woo, M. M., Leighl, N., Shepherd, F. A., Beck, J. T., Zhao, L., Gazi, L., Hengelage, T., Porro, M. G. & Nayak, A., Oct 1 2013, In : Cancer Chemotherapy and Pharmacology. 72, 4, p. 747-755 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Dextromethorphan
Substrates
Neoplasms
Dextrorphan
19 Citations (Scopus)

Adenosine A1 Receptors Promote Vasa Vasorum Endothelial Cell Barrier Integrity via Gi and Akt-Dependent Actin Cytoskeleton Remodeling

Siddaramappa, U. N., Kaczmarek, E., Fatteh, N., Burns, N., Lucas, R., Stenmark, K. R., Verin, A. D. & Gerasimovskaya, E. V., Apr 16 2013, In : PloS one. 8, 4, e59733.

Research output: Contribution to journalArticle

Vasa Vasorum
Adenosine A1 Receptors
Endothelial cells
adenosine
microfilaments
16 Citations (Scopus)

A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease

Kutlar, A., Reid, M. E., Inati, A., Taher, A. T., Abboud, M. R., El-Beshlawy, A., Buchanan, G. R., Smith, H., Ataga, K. I., Perrine, S. P. & Ghalie, R. G., Nov 1 2013, In : American Journal of Hematology. 88, 11

Research output: Contribution to journalArticle

2,2-dimethylbutyric acid
Globins
Sickle Cell Anemia
Sickle Hemoglobin
Fetal Hemoglobin
42 Citations (Scopus)

A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease

Wun, T., Soulieres, D., Frelinger, A. L., Krishnamurti, L., Novelli, E. M., Kutlar, A., Ataga, K. I., Knupp, C. L., McMahon, L. E., Strouse, J. J., Zhou, C., Heath, L. E., Nwachuku, C. E., Jakubowski, J. A., Riesmeyer, J. S. & Winters, K. J., Feb 19 2013, In : Journal of Hematology and Oncology. 6, 1, 17.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Placebos
Platelet Activation
P-Selectin
Platelet Aggregation Inhibitors
139 Citations (Scopus)

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

Monda, K. L., Chen, G. K., Taylor, K. C., Palmer, C., Edwards, T. L., Lange, L. A., Ng, M. C. Y., Adeyemo, A. A., Allison, M. A., Bielak, L. F., Chen, G., Graff, M., Irvin, M. R., Rhie, S. K., Li, G., Liu, Y., Liu, Y., Lu, Y., Nalls, M. A., Sun, Y. V. & 188 others, Wojczynski, M. K., Yanek, L. R., Aldrich, M. C., Ademola, A., Amos, C. I., Bandera, E. V., Bock, C. H., Britton, A., Broeckel, U., Cai, Q., Caporaso, N. E., Carlson, C. S., Carpten, J., Casey, G., Chen, W. M., Chen, F., Chen, Y. D. I., Chiang, C. W. K., Coetzee, G. A., Demerath, E., Deming-Halverson, S. L., Driver, R. W., Dubbert, P., Feitosa, M. F., Feng, Y., Freedman, B. I., Gillanders, E. M., Gottesman, O., Guo, X., Haritunians, T., Harris, T., Harris, C. C., Hennis, A. J. M., Hernandez, D. G., McNeill, L. H., Howard, T. D., Howard, B. V., Howard, V. J., Johnson, K. C., Kang, S. J., Keating, B. J., Kolb, S., Kuller, L. H., Kutlar, A., Langefeld, C. D., Lettre, G., Lohman, K., Lotay, V., Lyon, H., Manson, J. E., Maixner, W., Meng, Y. A., Monroe, K. R., Morhason-Bello, I., Murphy, A. B., Mychaleckyj, J. C., Nadukuru, R., Nathanson, K. L., Nayak, U., N'Diaye, A., Nemesure, B., Wu, S. Y., Leske, M. C., Neslund-Dudas, C., Neuhouser, M., Nyante, S., Ochs-Balcom, H., Ogunniyi, A., Ogundiran, T. O., Ojengbede, O., Olopade, O. I., Palmer, J. R., Ruiz-Narvaez, E. A., Palmer, N. D., Press, M. F., Rampersaud, E., Rasmussen-Torvik, L. J., Rodriguez-Gil, J. L., Salako, B., Schadt, E. E., Schwartz, A. G., Shriner, D. A., Siscovick, D., Smith, S. B., Wassertheil-Smoller, S., Speliotes, E. K., Spitz, M. R., Sucheston, L., Taylor, H., Tayo, B. O., Tucker, M. A., Van Den Berg, D. J., Edwards, D. R. V., Wang, Z., Wiencke, J. K., Winkler, T. W., Witte, J. S., Wrensch, M., Wu, X., Yang, J. J., Levin, A. M., Young, T. R., Zakai, N. A., Cushman, M., Zanetti, K. A., Zhao, J. H., Zhao, W., Zheng, Y., Zhou, J., Ziegler, R. G., Zmuda, J. M., Fernandes, J. K., Gilkeson, G. S., Kamen, D. L., Hunt, K. J., Spruill, I. J., Ambrosone, C. B., Ambs, S., Arnett, D. K., Atwood, L., Becker, D. M., Berndt, S. I., Bernstein, L., Blot, W. J., Borecki, I. B., Bottinger, E. P., Bowden, D. W., Burke, G., Chanock, S. J., Cooper, R. S., Ding, J., Duggan, D., Evans, M. K., Fox, C., Garvey, W. T., Bradfield, J. P., Hakonarson, H., Grant, S. F. A., Hsing, A., Chu, L., Hu, J. J., Huo, D., Ingles, S. A., John, E. M., Jordan, J. M., Kabagambe, E. K., Kardia, S. L. R., Kittles, R. A., Goodman, P. J., Klein, E. A., Kolonel, L. N., Le Marchand, L., Liu, S., McKnight, B., Millikan, R. C., Mosley, T. H., Padhukasahasram, B., Williams, L. K., Patel, S. R., Peters, U., Pettaway, C. A., Peyser, P. A., Psaty, B. M., Redline, S., Rotimi, C. N., Rybicki, B. A., Sale, M. M., Schreiner, P. J., Signorello, L. B., Singleton, A. B., Stanford, J. L., Strom, S. S., Thun, M. J., Vitolins, M., Zheng, W., Moore, J. H., Williams, S. M., Ketkar, S., Zhu, X., Zonderman, A. B., Kooperberg, C., Papanicolaou, G. J., Henderson, B. E., Reiner, A. P., Hirschhorn, J. N., Loos, R. J. F., North, K. E. & Haiman, C. A., Jun 1 2013, In : Nature Genetics. 45, 6, p. 690-696 7 p.

Research output: Contribution to journalArticle

Meta-Analysis
Body Mass Index
Genome-Wide Association Study
Population
Single Nucleotide Polymorphism
18 Citations (Scopus)
Caspases
Cells
Apoptosis
Derivatives
Pharmaceutical Preparations
25 Citations (Scopus)

Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy

Mkrtichyan, M., Chong, N., Eid, R. A., Wallecha, A., Singh, R., Rothman, J. & Khleif, S. N., Jan 1 2013, In : Journal for ImmunoTherapy of Cancer. 1, 15.

Research output: Contribution to journalArticle

Death Domain Receptors
Listeria monocytogenes
Immunotherapy
Antibodies
Neoplasms
8 Citations (Scopus)

A phase 2 study of oxaliplatin combined with continuous infusion topotecan for patients with previously treated ovarian cancer

Stein, S. M., Tiersten, A., Hochster, H. S., Blank, S. V., Pothuri, B., Curtin, J., Shapira, I., Levinson, B., Ivy, P., Joseph, B., Guddati, A. K. & Muggia, F., Dec 2 2013, In : International Journal of Gynecological Cancer. 23, 9, p. 1577-1582 6 p.

Research output: Contribution to journalArticle

oxaliplatin
Topotecan
Platinum
Ovarian Neoplasms
Intravenous Infusions
37 Citations (Scopus)

Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonaryhypertension

Rafikova, O., Rafikov, R., Kumar, S., Sharma, S., Aggarwal, S., Schneider, F., Jonigk, D., Black, S. M. & Tofovic, S. P., Mar 1 2013, In : Free Radical Biology and Medicine. 56, p. 28-43 16 p.

Research output: Contribution to journalArticle

Oxidative stress
Pulmonary Hypertension
Endothelin-1
Oxidative Stress
Cell proliferation
27 Citations (Scopus)

Comparable efficacy and lower cost of PBSC mobilization with intermediate-dose cyclophosphamide and G-CSF compared with plerixafor and G-CSF in patients with multiple myeloma treated with novel therapies

Awan, F., Kochuparambil, S. T., Falconer, D. E., Cumpston, A., Leadmon, S., Watkins, K., Deremer, D., Jillella, A., Craig, M. & Hamadani, M., Oct 1 2013, In : Bone marrow transplantation. 48, 10, p. 1279-1284 6 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
Multiple Myeloma
Cyclophosphamide
Costs and Cost Analysis
Hematopoietic Stem Cell Mobilization
5 Citations (Scopus)

Comparison of hematologic measurements between local and central laboratories: Data from the BABY HUG trial

Kalpatthi, R., Thompson, B., Lu, M., Wang, W. C., Patel, N., Kutlar, A., Howard, T., Luchtman-Jones, L. & Miller, S. T., Feb 1 2013, In : Clinical Biochemistry. 46, 3, p. 278-281 4 p.

Research output: Contribution to journalArticle

Monocytes
Neutrophils
Blood
Clinical Trials
Erythrocyte Indices
204 Citations (Scopus)

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors

Marabelle, A., Kohrt, H., Sagiv-Barfi, I., Ajami, B., Axtell, R. C., Zhou, G., Rajapaksa, R., Green, M. R., Torchia, J., Brody, J., Luong, R., Rosenblum, M. D., Steinman, L., Levitsky, H. I., Tse, V. & Levy, R., Jun 3 2013, In : Journal of Clinical Investigation. 123, 6, p. 2447-2463 17 p.

Research output: Contribution to journalArticle

Neoplasms
Immunomodulation
Immunotherapy
Lymphoma
Therapeutics