Hematology and Oncology

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2009

Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia-lymphoma: A proposal from an international consensus meeting

Tsukasaki, K., Hermine, O., Bazarbachi, A., Ratner, L., Ramos, J. C., Harrington, W., O'Mahony, D., Janik, J. E., Bittencourt, A. L., Taylor, G. P., Yamaguchi, K., Utsunomiya, A., Tobinai, K. & Watanabe, T., Jan 20 2009, In : Journal of Clinical Oncology. 27, 3, p. 453-459 7 p.

Research output: Contribution to journalArticle

332 Scopus citations
69 Scopus citations

Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma

Dunleavy, K., Pittaluga, S., Czuczman, M. S., Dave, S. S., Wright, G., Grant, N., Shovlin, M., Jaffe, E. S., Janik, J. E., Staudt, L. M. & Wilson, W. H., Nov 19 2009, In : Blood. 113, 24, p. 6069-6076 8 p.

Research output: Contribution to journalArticle

382 Scopus citations

EBV-related lymphoproliferative disease complicating therapy with the anti-CD2 monoclonal antibody, siplizumab, in patients with t-cell malignancies

O'Mahony, D., Morris, J. C., Stetler-Stevenson, M., Matthews, H., Brown, M. R., Fleisher, T., Pittaluga, S., Raffeld, M., Albert, P. S., Reitsma, D., Kaucic, K., Hammershaimb, L., Waldmann, T. A. & Janik, J. E., Apr 1 2009, In : Clinical Cancer Research. 15, 7, p. 2514-2522 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Effect of PPARγ inhibition on pulmonary endothelial cell gene expression: Gene profiling in pulmonary hypertension

Tian, J., Smith, A., Nechtman, J., Podolsky, R., Aggarwal, S., Snead, C., Kumar, S., Elgaish, M., Oishi, P., Göerlach, A., Fratz, S., Hess, J., Catravas, J. D., Verin, A. D., Fineman, J. R., She, J. X. & Black, S. M., Jan 1 2009, In : Physiological Genomics. 40, 1, p. 48-60 13 p.

Research output: Contribution to journalArticle

35 Scopus citations
8 Scopus citations

Gene expression profiling of ATL patients: Compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability

Pise-Masison, C. A., Radonovich, M., Dohoney, K., Morris, J. C., O'Mahony, D., Lee, M. J., Trepel, J., Waldmann, T. A., Janik, J. E. & Brady, J. N., Nov 17 2009, In : Blood. 113, 17, p. 4016-4026 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

GTP cyclohydrolase I expression is regulated by nitric oxide: Role of cyclic AMP

Kumar, S., Sun, X., Sharma, S., Aggarwal, S., Ravi, K., Fineman, J. R. & Black, S. M., Aug 1 2009, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 297, 2, p. L309-L317

Research output: Contribution to journalArticle

12 Scopus citations

Hb M Dothan [β 25/26 (B7/B8)/(GGT/GAG→GAG//Gly/Glu→Glu]; a new mechanism of unstable methemoglobin variant and molecular characteristics

Kutlar, F., Hilliard, L. M., Zhuang, L., Patel, N., Eroglu, B., Meiler, S. E., Carmichael, H., Russell, R. B. & Kutlar, A., Nov 1 2009, In : Blood Cells, Molecules, and Diseases. 43, 3, p. 235-238 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Hepatic failure caused by plasma cell infiltration in multiple myeloma

Rahhal, F. E., Schade, R. R., Nayak, A. & Coleman, T. A., Apr 28 2009, In : World Journal of Gastroenterology. 15, 16, p. 2038-2040 3 p.

Research output: Contribution to journalArticle

12 Scopus citations

Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of Sp1 activity

Kumar, S., Sun, X., Wiseman, D. A., Tian, J., Umapathy, N. S., Verin, A. D. & Black, S. M., Mar 1 2009, In : DNA and cell biology. 28, 3, p. 119-129 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
13 Scopus citations

Monoclonal antibody therapy of T cell lymphoma: Single agent trials of anti-CD2 (Siplizumab) and anti-CD4 (Humax-CD4)

Janik, J. E., O'Mahony, D., Waldmann, T. A. & Morris, J. C., Sep 9 2009, In : Haematologica Meeting Reports. 3, 1, p. 61-68 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Plasmablastic lymphoma: CNS involvement, coexistence of other malignancies, possible viral etiology, and dismal outcome

Ustun, C., Reid-Nicholson, M., Nayak-Kapoor, A., Jones-Crawford, J., McDonald, K., Jillella, A. P. & Ramalingam, P., Jan 1 2009, In : Annals of Hematology. 88, 4, p. 351-358 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Probiotic-associated high-titer anti-b in a group a platelet donor as a cause of severe hemolytic transfusion reactions

Daniel-Johnson, J., Leitman, S., Klein, H., Alter, H., Lee-Stroka, A., Scheinberg, P., Pantin, J. & Quillen, K., Sep 1 2009, In : Transfusion. 49, 9, p. 1845-1849 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Rare occurrence of Hb Lepore-Baltimore in African Americans: Molecular characteristics and variations of Hb Lepores

McKeown, S. M., Carmichael, H., Markowitz, R-B., Kutlar, A., Holley, L. & Kutlar, F., Jun 1 2009, In : Annals of Hematology. 88, 6, p. 545-548 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Reactivation of DNA viruses in association with histone deacetylase inhibitor therapy: A case series report

Ritchie, D. S., Piekarz, R. L., Blombery, P., Karai, L. J., Pittaluga, S., Jaffe, E. S., Raffeld, M., Janik, J. E., Miles Prince, H. & Bates, S. E., Nov 1 2009, In : Haematologica. 94, 11, p. 1618-1622 5 p.

Research output: Contribution to journalArticle

46 Scopus citations

Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury

Adamkiewicz, T. V., Abboud, M. R., Paley, C., Olivieri, N., Kirby-Allen, M., Vichinsky, E., Casella, J. F., Alvarez, O. A., Barredo, J. C., Lee, M. T., Iyer, R. V., Kutlar, A., McKie, K. M., McKie, V., Odo, N., Gee, B., Kwiatkowski, J. L., Woods, G. M., Coates, T., Wang, W. & 1 others, Adams, R. J., Nov 19 2009, In : Blood. 114, 21, p. 4632-4638 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Strategies to Improve Long-Term Outcome in Stage IIIB Inflammatory Breast Cancer: Multimodality Treatment Including Dose-Intensive Induction and High-Dose Chemotherapy

Sportès, C., Steinberg, S. M., Liewehr, D. J., Gea-Banacloche, J., Danforth, D. N., Avila, D. N., Bryant, K. E., Krumlauf, M. C., Fowler, D. H., Pavletic, S., Hardy, N. M., Bishop, M. R. & Gress, R. E., Aug 1 2009, In : Biology of Blood and Marrow Transplantation. 15, 8, p. 963-970 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Survivin(g) adult T-cell leukemia/lymphoma.

Janik, J. E. & Morris, J. C., Dec 1 2009, In : Oncology (Williston Park, N.Y.). 23, 14

Research output: Contribution to journalArticle

1 Scopus citations

The carboxyl-terminal domain of Atypical protein kinase Cζ binds to ceramide and regulates junction formation in Epithelial cells

Wang, G., Krishnamurthy, K., Umapathy, N. S., Verin, A. D. & Bieberich, E., May 22 2009, In : Journal of Biological Chemistry. 284, 21, p. 14469-14475 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: A phase III double-blind crossover study (N01CB)

Cheville, A. L., Sloan, J. A., Northfelt, D. W., Jillella, A., Wong, G. Y., Bearden, J. D., Liu, H., Schaefer, P. L., Marchello, B. T., Christensen, B. J. & Loprinzi, C. L., Apr 1 2009, In : Supportive Care in Cancer. 17, 4, p. 451-460 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Variable CD52 expression in mature T cell and NK cell malignancies: Implications for alemtuzumab therapy

Jiang, L., Yuan, C. M., Hubacheck, J., Janik, J. E., Wilson, W., Morris, J. C., Jasper, G. A. & Stetler-Stevenson, M., Apr 1 2009, In : British Journal of Haematology. 145, 2, p. 173-179 7 p.

Research output: Contribution to journalArticle

61 Scopus citations
2008

Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing

Ma, W., Chen, J., Xue, X., Wang, Z., Liu, H., Wang, T., Bai, Y., Tang, S-C. & Zhou, Q., Jul 4 2008, In : Biochemical and Biophysical Research Communications. 371, 3, p. 425-430 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension

Sharma, S., Sud, N., Wiseman, D. A., Carter, A. L., Kumar, S., Hou, Y., Rau, T., Wilham, J., Harmon, C., Oishi, P., Fineman, J. R. & Black, S. M., Jan 1 2008, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 294, 1, p. L46-L56

Research output: Contribution to journalArticle

49 Scopus citations

Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Burbelo, P. D., Meoli, E., Leahy, H. P., Graham, J., Yao, K., Oh, U., Janik, J. E., Mahieux, R., Kashanchi, F., Iadarola, M. J. & Jacobson, S., Oct 20 2008, In : Retrovirology. 5, 96.

Research output: Contribution to journalArticle

38 Scopus citations

Brain metastases in N2-positive non-small-cell lung cancer: Implications for prophylactic cranial irradiation

Bansal, M., Boyle, T., Ehsan, A. & Mott, F. E., Jul 2008, In : Clinical Lung Cancer. 9, 4, p. 227-229 3 p.

Research output: Contribution to journalArticle

Calcium/calmodulin-dependent phosphorylation of tumor protein D52 on serine residue 136 may be mediated by CAMK2δ6

Chew, C. S., Chen, X., Zhang, H., Berg, E. A. & Zhang, H., Dec 1 2008, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 295, 6, p. G1159-G1172

Research output: Contribution to journalArticle

11 Scopus citations

Cardiac involvement with human T-cell lymphotrophic virus type-1-associated adult T-cell leukemia/lymphoma: The NIH experience

O'Mahony, D., Debnath, I., Janik, J. E., Aisner, D., Jaffe, E., Waldmann, T. & Morris, J., Mar 1 2008, In : Leukemia and Lymphoma. 49, 3, p. 439-446 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation

Bishop, M. R., Dean, R. M., Steinberg, S. M., Odom, J., Pavletic, S. Z., Chow, C., Pittaluga, S., Sportes, C., Hardy, N. M., Gea-Banacloche, J., Kolstad, A., Gress, R. E. & Fowler, D. H., Nov 3 2008, In : Annals of Oncology. 19, 11, p. 1935-1940 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Colon cancer 15 years after ureterosigmoidostomy

Chan, C. C. W., Tan, A. & Salman, H., Sep 15 2008, In : Journal of Clinical Oncology. 26, 10, p. 1755-1757 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Coombs'-negative autoimmune hemolytic anemia in a patient with small lymphocytic lymphoma involving the bone marrow

Savage, N., Georgi, D., Kutlar, A. & Cook, L., Dec 1 2008, In : Laboratory Medicine. 39, 8, p. 465-466 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells

Fiskus, W., Wang, Y., Joshi, R., Rao, R., Yang, Y., Chen, J., Kolhe, R., Balusu, R., Eaton, K., Lee, P., Ustun, C., Jillella, A., Buser, C. A., Peiper, S. & Bhalla, K., Oct 1 2008, In : Clinical Cancer Research. 14, 19, p. 6106-6115 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Disparity in the management of iron overload between patients with sickle cell disease and thalassemia who received transfusions

Fung, E. B., Harmatz, P. R., Milet, M., Balasa, V., Ballas, S. K., Casella, J. F., Hilliard, L., Kutlar, A., McClain, K. L., Olivieri, N. F., Porter, J. B., Vichinsky, E. P., Bellevue, R., Coates, T., Darbari, D., Davis, C., DeCastro, L., Giardina, P., Hord, J., Jeng, M. & 16 others, Kirby, M., Mignaca, R., Mentzer, W., Olivieri, N., Owen, W., Pegelow, C., Porter, J., Ramirez, G., Ranalli, M., Rao, S., Scher, C., Shafer, F., Smith, M. G., Smith-Whitney, K., Thompson, A. & Wang, W., Sep 1 2008, In : Transfusion. 48, 9, p. 1971-1980 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

DNA, but not protein vaccine based on mutated BORIS antigen significantly inhibits tumor growth and prolongs the survival of mice

Mkrtichyan, M., Ghochikyan, A., Loukinov, D., Davtyan, H., Ichim, T. E., Cribbs, D. H., Lobanenkov, V. V. & Agadjanyan, M. G., Jan 1 2008, In : Gene Therapy. 15, 1, p. 61-64 4 p.

Research output: Contribution to journalArticle

18 Scopus citations

DNA epitope vaccine containing complement component C3d enhances anti-amyloid-β antibody production and polarizes the immune response towards a Th2 phenotype

Movsesyan, N., Mkrtichyan, M., Petrushina, I., Ross, T. M., Cribbs, D. H., Agadjanyan, M. G. & Ghochikyan, A., Dec 15 2008, In : Journal of Neuroimmunology. 205, 1-2, p. 57-63 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

Ataga, K. I., Smith, W. R., De Castro, L. M., Swerdlow, P., Saunthararajah, Y., Castro, O., Vichinsky, E., Kutlar, A., Orringer, E. P., Rigdon, G. C. & Stacker, J. W., Apr 15 2008, In : Blood. 111, 8, p. 3991-3997 7 p.

Research output: Contribution to journalArticle

139 Scopus citations

Escape from suppression: Tumor-specific effector cells outcompete regulatory T cells following stem-cell transplantation

Mirmonsef, P., Tan, G., Zhou, G., Morino, T., Noonan, K., Borrello, I. & Levitsky, H. I., Feb 15 2008, In : Blood. 111, 4, p. 2112-2121 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells

Umapathy, N. S., Dun, Y., Martin, P. M., Duplantier, J. N., Roon, P., Prasad, P., Smith, S. B. & Ganapathy, V., Nov 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 5151-5160 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Ferroportin q248h, dietary iron, and serum ferritin in community African-Americans with low to high alcohol consumption

Gordeuk, V. R., Diaz, S. F., Onojobi, G. O., Kasvosve, I., Debebe, Z., Edossa, A., Pantin, J. M., Xiong, S., Nekhai, S., Nouraie, M., Tsukamoto, H. & Taylor, R. E., Nov 1 2008, In : Alcoholism: Clinical and Experimental Research. 32, 11, p. 1947-1953 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Hemoglobin binding to Aβ and HBG2 SNP association suggest a role in Alzheimer's disease

Perry, R. T., Gearhart, D. A., Wiener, H. W., Harrell, L. E., Barton, J. C., Kutlar, A., Kutlar, F., Ozcan, O., Go, R. C. P. & Hill, W. D., Feb 1 2008, In : Neurobiology of Aging. 29, 2, p. 185-193 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
34 Scopus citations

Immunogenicity of a multi-component recombinant human acrosomal protein vaccine in female Macaca fascicularis

Kurth, B. E., Digilio, L., Snow, P., Bush, L. A., Wolkowicz, M., Shetty, J., Mandal, A., Hao, Z., Reddi, P. P., Flickinger, C. J. & Herr, J. C., Apr 1 2008, In : Journal of Reproductive Immunology. 77, 2, p. 126-141 16 p.

Research output: Contribution to journalArticle

17 Scopus citations

Immunostimulant adjuvant patch enhances humoral and cellular immune responses to DNA immunization

Mkrtichyan, M., Ghochikyan, A., Movsesyan, N., Karapetyan, A., Begoyan, G., Yu, J., Glenn, G. M., Ross, T. M., Agadjanyan, M. G. & Cribbs, D. H., Jan 1 2008, In : DNA and cell biology. 27, 1, p. 19-24 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-eell leukemia cells by a paracrine mechanism

Chen, J., Petrus, M., Bryant, B. R., Nguyen, V. P., Stamer, M., Goldman, C. K., Bamford, R., Morris, J. C., Janik, J. E. & Waldmann, T. A., May 15 2008, In : Blood. 111, 10, p. 5163-5172 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Mannan-Abeta28 conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice

Petrushina, I., Ghochikyan, A., Mkrtichyan, M., Mamikonyan, G., Movsesyan, N., Ajdari, R., Vasilevko, V., Karapetyan, A., Lees, A., Agadjanyan, M. G. & Cribbs, D. H., Sep 29 2008, In : Journal of Neuroinflammation. 5, 42.

Research output: Contribution to journalArticle

32 Scopus citations

Neonatal cyanosis due to a novel fetal hemoglobin: Hb F-Circleville [ Gγ63(E7)His→Leu, CAT>CTT]

Dainer, E., Shell, R., Miller, R., Atkin, J. F., Pastore, M., Kutlar, A., Zhuang, L., Holley, L., Davis, D. H. & Kutlar, F., Nov 1 2008, In : Hemoglobin. 32, 6, p. 596-600 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Nilotinib: A second-generation tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia

DeRemer, D. L., Ustun, C. & Natarajan, K., Nov 1 2008, In : Clinical Therapeutics. 30, 11, p. 1956-1975 20 p.

Research output: Contribution to journalArticle

108 Scopus citations

Phase II study of dose-adjusted EPOCH and rituximab in untreated diffuse large B-cell lymphoma with analysis of germinal center and post-germinal center biomarkers

Wilson, W. H., Dunleavy, K., Pittaluga, S., Hegde, U., Grant, N., Steinberg, S. M., Raffeld, M., Gutierrez, M., Chabner, B. A., Staudt, L., Jaffe, E. S. & Janik, J. E., Sep 15 2008, In : Journal of Clinical Oncology. 26, 16, p. 2717-2724 8 p.

Research output: Contribution to journalArticle

213 Scopus citations

Plasmablastic lymphoma: Cytologic findings in 5 cases with unusual presentation.

Reid-Nicholson, M., Kavuri, S., Ustun, C., Crawford, J., Nayak-Kapoor, A. & Ramalingam, P., Oct 25 2008, In : Cancer. 114, 5, p. 333-341 9 p.

Research output: Contribution to journalArticle

16 Scopus citations