Projects 1975 2019

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VASCULAR MECHANISMS IN ATHEROGENESIS

Lentz, S., Faraci, F., Farci, F., Sigmund, C. D., Heistad, D. & Weintraub, N. L.

National Institutes of Health

6/1/004/30/16

Project: Research project

Surface-Active Agents
Smooth Muscle Myocytes
Pulmonary Surfactant-Associated Protein D
Blood Vessels
Inflammation

VACCINE TO TREAT CHRONIC HEPATITIS B VIRUS INFECTION

Vitello, M., Chesnut, R. & Celis, E.

National Institutes of Health

4/1/924/30/97

Project: Research project

Cytotoxic T-Lymphocytes
Hepatitis B virus
Vaccines
T-Lymphocyte Epitopes
Chronic Hepatitis B
Myeloid Cells
Carcinogenesis
Neoplasms
Inflammation
Kupffer Cells
Subunit Vaccines
Melanoma
Vaccines
T-Lymphocytes
Neoplasms

TOLERANCE EVASION BY SELF MHC SPECIFIC T CELLS

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

7/15/985/31/02

Project: Research project

T-Lymphocytes
Peptides
Thymocytes
T-Cell Antigen Receptor
Transgenic Mice

The Role of Endothelin-1 in Sickle Cell Disease

Meiler, S., Pollock, D. & Kutlar, A.

National Institutes of Health

8/15/135/31/18

Project: Research project

Sickle Cell Anemia
Endothelin-1
Translational Medical Research
Research
Pain
Cytotoxic T-Lymphocytes
Prostatic Neoplasms
Vaccines
T-Lymphocyte Epitopes
Immunotherapy
African Americans
Tobacco
Living Wills
Tobacco Use

T cell regulation by IDO-competent plasmacytoid dendritic cells

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

5/22/094/30/12

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
T-Lymphocytes
Islets of Langerhans
Inflammation

T CELL IMMUNOREGULATION BY TRYPTOPHAN DEPLETION

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

12/1/983/31/04

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tryptophan
T-Lymphocytes
Embryo Loss
Isoantigens
Molecular Chaperones
Neurodegenerative Diseases
Molecular Probes
Humulus
Metabolic Diseases

Stress Related Mechanisms of Hypertension Risk

Gutin, B., Layman, L., Pollock, D., Treiber, F., Pollock, J., Strong, W., Smith, D., George, V., Dong, Y., Kapuku, K. G. & Harshfield, G. A.

National Institutes of Health

7/1/026/30/19

Project: Research project

Hypertension
Renin-Angiotensin System
Natriuresis
Sodium
Biological Assay

SPORE in Prostate Cancer

Young, C., Fatemi, M., Morris, J. C., Thibodeau, S. N., Vile, R., Vasmatzis, G., Jenkins, R. B., Bergstralh, E. J., Cheville, J., Klee, G., Tindall, D. J., Davis, B., Sargent, D., Layton, D., Vuk-Pavlovic, S. & Celis, E.

National Institutes of Health

8/31/018/31/13

Project: Research project

Prostatic Neoplasms
Cytotoxic T-Lymphocytes
Helper-Inducer T-Lymphocytes
Neoplasms
Therapeutics
African Americans
Sodium
Bone and Bones
Metabolic Bone Diseases
Bone Density
T-Lymphocytes
Recurrence
Drug Therapy
Neoplasms
Immunity

RENAL RESEARCH TRAINING PROGRAM

Madaio, M. P., Neilson, E., Turka, L., Agus, Z. & Holzman, L. B.

National Institutes of Health

7/1/756/30/06

Project: Research project

Regulation of T cell immunity by indol 2,3 dioxygenase

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

4/1/023/31/08

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dioxygenases
Immunity
T-Lymphocytes
Complement Activation
Catenins
beta Catenin
Dendritic Cells
Inflammation
Inflammatory Bowel Diseases
Dendritic Cells
Immunity
Allergy and Immunology
Neoplasms
Cell Biology
African Americans
Natriuresis
Vasoconstriction
Homeostasis
Hemodynamics
rural community
nicotine
morbidity
mortality
school system

PROGRAM PROJECT FATTY ACIDS, LIPOPROTEINS &LIPID OXIDAT

Knapp, H., Field, F. J., Chappell, D., Spector, A. & Weintraub, N. L.

National Institutes of Health

9/30/928/31/03

Project: Research project

Coronary Circulation
Blood Vessels
Coronary Vessels
Microvessels
Acids
Catenins
Dendritic Cells
Autoimmune Experimental Encephalomyelitis
Brain
Multiple Sclerosis
HLA-G Antigens
Dendritic Cells
Transplantation
Allografts
T-Lymphocytes
Campylobacter jejuni
Virulence
Regulon
Gastroenteritis
Biofilms
Angiotensin II
High Fat Diet
Adipose Tissue
Atherosclerosis
Blood Vessels
Subunit Vaccines
Neoplasms
Cytotoxic T-Lymphocytes
Helper-Inducer T-Lymphocytes
T-Lymphocyte Epitopes
Blood Vessels
Type 2 Diabetes Mellitus
Indoleamine-Pyrrole 2,3,-Dioxygenase
Arginase
Cytokines
Nephritis
Podocytes
Peptides
Glomerulonephritis
Endothelial Cells
Defecation
Constipation
Brain
Therapeutics
Laxatives
Fecal Incontinence
Therapeutics
Lower Gastrointestinal Tract
Pelvic Floor
Muscle Strength

NCMHD Southeastern Exploratory Sickle Cell Center of Excellence

Adamkiewicz, T., Gibson, R. W., Ikuta, T., Kutlar, A., Gibson, R. W., Gibson, R. W. & Tuan Lo, D.

National Institutes of Health

5/28/0912/31/15

Project: Research project

Sickle Cell Anemia
Hydroxyurea
gamma-Globins
Globins
Opioid Analgesics

MOLECULAR REGULATION OF ENDOTHELIAL CELL PERMEABILITY

Langan, G. P., Ratneshwar, L., Garcia, J. G. N., Birukov, K., Natarajan, V., Salgia, R., English, D. K., Patterson, C., Romer, L., Crow, M. T., Hassoun, P. & Verin, A. D.

National Institutes of Health

2/1/981/31/14

Project: Research project

Microtubules
Lung
Endothelial Cells
Permeability
Myosin Light Chains

MOLECULAR MECHANISMS OF RENAL INFLAMMATION AND INJURY

Madaio, M. P., Gasser, D., Cooke, N., Kelly, C., Ziyadeh, F. & Neilson, E.

National Institutes of Health

8/1/927/31/03

Project: Research project

Kidney
Antinuclear Antibodies
Wounds and Injuries
Collagen
Collagen Type IV

MOLECULAR ANALYSIS OF HUMAN ANTIGBM ANTIBODIES

Madaio, M. P.

National Institutes of Health

9/1/976/30/06

Project: Research project

Antibodies
Glomerular Basement Membrane
T-Lymphocytes
Clone Cells
Kidney
Nephritis
Antibodies
Pharmaceutical Preparations
Kidney
Glomerulonephritis
Spinal Cord Diseases
Veterans
Spinal Cord Injuries
Bone Density
Photon Absorptiometry

Mini-plasmin: Pre-Clinical Evaluation of a Novel Thrombolytic Strategy for Stroke

Sazonova, I. Y., Pellock, J., Pellock, J. & Verin, A.

National Institutes of Health

12/7/871/31/15

Project: Research project

Fibrinolysin
Stroke
Tissue Plasminogen Activator
Fibrinolytic Agents
Thrombolytic Therapy
Microtubules
Endothelial Cells
Lung
Thrombin
Phosphorylation
Blood Pressure
Kidney
Salts
Sodium
Research

Mechanisms of Vascular Dysfunction in Cirrhosis

Khurana, S.

National Institutes of Health

7/28/086/30/14

Project: Research project

Bile Acids and Salts
Gastroenterology
Blood Vessels
Vasodilation
Fibrosis
Calmodulin
Thrombin
Endothelial Cells
Permeability
Myosin-Light-Chain Kinase
Immunity
Immunization
T-Lymphocytes
Antigen Presentation
Immunotherapy

Manipulating natural host immunoregulation via IDO during viral Infection

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

5/1/094/30/15

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Virus Diseases
T-Lymphocytes
Regulatory T-Lymphocytes
Infection

IN VIVO STUDIES OF VCAM-1 IN IMMUNITY

Koni, P.

National Institutes of Health

7/1/015/31/07

Project: Research project

Vascular Cell Adhesion Molecule-1
Immunity
T-Lymphocytes
Dendritic Cells
Peripheral Tolerance
Subunit Vaccines
Interferon-gamma
T-Lymphocytes
Neoplasms
Immunotherapy
Natriuresis
Interleukin-6
Pressure
C-Reactive Protein
Genes
Gene Deletion
Proteins
Transgenes
Research Personnel
Genetic Recombination