Projects 1975 2019

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Research project

Mini-plasmin: Pre-Clinical Evaluation of a Novel Thrombolytic Strategy for Stroke

Sazonova, I. Y., Pellock, J., Pellock, J. & Verin, A.

National Institutes of Health

12/7/871/31/15

Project: Research project

Fibrinolysin
Stroke
Tissue Plasminogen Activator
Fibrinolytic Agents
Thrombolytic Therapy

GLOMERULAR IMMUNE DEPOSIT FORMATION IN SLE

Madaio, M. P.

National Institutes of Health

1/1/8512/31/87

Project: Research project

Systemic Lupus Erythematosus
Immunoglobulins
Lupus Nephritis
Antinuclear Antibodies
Antigen-Antibody Complex

IN VIVO STUDIES OF VCAM-1 IN IMMUNITY

Koni, P.

National Institutes of Health

7/1/015/31/07

Project: Research project

Vascular Cell Adhesion Molecule-1
Immunity
T-Lymphocytes
Dendritic Cells
Peripheral Tolerance

Mechanisms of Vascular Dysfunction in Cirrhosis

Khurana, S.

National Institutes of Health

7/28/086/30/14

Project: Research project

Bile Acids and Salts
Gastroenterology
Blood Vessels
Vasodilation
Fibrosis

GENERAL CLINICAL RESEARCH CENTER

Mahan, J., Novak, V., Colombo, D., Marucha, P. T., Durnwald, C., Pesavento, T., Corrigan, J., Boudoulas, H., Coyle, J., Cromer, B., Friedman, C., Lima, J., Arnold, M., Wright, J. G., Falko, J. M., Dasta, J., Gerber, N., Leier, C., Lamb, D., Ellison, E. C., Cosio, F., Hartman, J., Grever, M. R., Fabri, P., Zipf, W., Bay, W., Binkley, P. F., Bornstein, R., Allred, J., Snively, T., Cacioppo, J. T., Leenders, N., Pollak, C., Reynolds, N., Glaser, R., Tzagournis, M., Para, M., Rovin, B., Frid, D., West, S., Moser, D., Iams, J., Schwartz, S., Hughes, J., Moore, J. L., Sedmak, D., Rammohan, K., Chan, K., Aman, M. G., Shapiro, C., Lynn, D., Koletar, S., Landon, M., Diaz, P., Carson, W. E., Schuster, D., Snively, T., Cacioppo, J. T., Leenders, N., Pollak, C., Stoney, C., Grecula, J., Lennie, T., Frazier, S. K., Diaz, P., Carson, W. E., Shapiro, C., Para, M. F., Robles, T., Clark, D., Loucks, A., Jackson, R., Schwartz, S., Schuster, D., Kissel, J., Iams, J. A. Y., Paskett, E. D., Emery, C. F., Malarkey, W. B., Aman, M. G., Belury, M., Andersen, B. L., Buckworth, J., Beversdorf, D. Q., Arnold, L. E., Osei, K. N., Habash, D., Ahijevych, K., Mendell, J., Salsberry, P., Diaz, P., Hiremath, L., Rammohan, K., Yee, L., Para, M. F., Elsheikh, B., Lynn, D., Raman, S., Bauer, H., Reiss, R., Reuning, R., vandecreek, L., Wooding-Scott, R., Washington, S., Leiby, J. M., O'Dorisio, S. U. E., Levy, A. B., Wright, F., Panganamala, R., Jaeckle, R., Majetich, N., Nelson, S., Schmidt, H., Kudsk, K., Donnerberg, R. L., Moon, K., Reitz, J., Wooley, C., Warren, L., Mysiw, J., Cataland, S., Caccioppo, J., Ruymann, F., O'Dorisio, T., McNeil, D., O'Dorsio, T., Walson, P., Kraut, E. R., Pearson, A., Schiller, M. R., Greenson, J., Tesi, R., Thomas, F., Benes, S., Herbert, L., Brobeck, E., Foley, M., Flako, J., Schaal, S., Hurley, R., Caldwell, J., O'Dorisio, S., O'Dorisio, M., Quick, D., Bremseth, D., Davis, B., Chang, F., Malarky, W., Marlarkey, W. B., Kiecolt-Glaser, J., Allen, C., Fass, R. J., Tzebiatowski, G., Zuelzer, W., Kolibash, A., Schroeder, K., Starling, R., Carey, L., Nester, T., Hudson, N. P., O'Dorisio, M., Boyne, L., Camisa, C., Visconti, J., Rinehart, J., Sloan, H., MacKichan, J., Hirsch, S., Drake, M., Nahman, N. S., Neidhart, J., Zollinger, R., Strauss, R., Earle, S. B., Bossetti, B., Behrens, B., Balcerzak, S., Rogers, J., Gora, M., Ferguson, R., Kiecolt-Glaser, J., Kang, D., Levy, C., Triozzi, P., McKenna, D., Fish, A., Stout-Shafer, S., Goodman, J., Brugge, K., Whitacre, C., Caligiuri, M., Gilles, E., Burgun, S., Fass, R., Zaqqa, D., Wininger, D., Preshaw, P., Henry, M., Kraut, E., Magorien, R., Sanfilippo, A., Flancbaum, L., Pollack, C., Kirby, T., Souba, W. W., Kang, D., Levy, C., Triozzi, P., McAuley, J., Kiecolt-Glaser, J., Hubble, J., Bates, S., McKenna, D., Fish, A., Stout-Shafer, S., Goodman, J., Caligiuri, M., Porcu, P., Kraut, E., Buck, J., Hall, C., Kaumaya, P. T., Wininger, D., Lin, T., Smith, A., Nash, S., Hoffman, R., Medeiros, L., Marcucci, G., Fristad, M., Haines, D., Pajer, K., Corwin, E., Mastronarde, J., Grzybowski, D., Wininger, D., Kirby, T. I. M., Roe, B., Shneker, B., Racke, M., Hawker, K. S., Borchers, J., Rajab, A., Parthasarathy, S., Paulson, G., Hebert, L. A., Kiecolt-Glaser, J. A. N., Disilvestro, R., Nahman, S., Ehrman, J., Jhiang, S., Sharma, H., Engebretson, T., Schwartzbaum, J., Boyle, J., Berntson, G. G., Stone, K. S., Sotos, J., Kien, C. L., Mazzaferri, E., McAuley, J., Schirmer, W., Kissel, J., Cottrell, D., Loucks, A., Mendell, J., Wewers, M. E., Hebert, L., Andersen, B., Gadek, J., Jackson, R. D., Stoney, C., Matkovic, V., Ahijevych, K., Malarkey, W. B., Osei, K., Davis, W. B. & Nahman, N. S.

National Institutes of Health

12/1/7611/30/09

Project: Research project

Research Personnel
Vitamin E
Cystic Fibrosis
Tobacco Products
Respiratory System
Epigenomics
Type 2 Diabetes Mellitus
Methylation
Cardiovascular Diseases
Obesity

VASCULAR MECHANISMS IN ATHEROGENESIS

Lentz, S., Faraci, F., Farci, F., Sigmund, C. D., Heistad, D. & Weintraub, N. L.

National Institutes of Health

6/1/004/30/16

Project: Research project

Surface-Active Agents
Smooth Muscle Myocytes
Pulmonary Surfactant-Associated Protein D
Blood Vessels
Inflammation
Nephritis
Podocytes
Peptides
Glomerulonephritis
Endothelial Cells
Acute Lung Injury
Endothelial Cells
Protein Kinase C-alpha
Adenosine
Proteins
Spinal Cord Diseases
Veterans
Spinal Cord Injuries
Bone Density
Photon Absorptiometry
rural community
nicotine
morbidity
mortality
school system
Cytotoxic T-Lymphocytes
Prostatic Neoplasms
Vaccines
T-Lymphocyte Epitopes
Immunotherapy
African Americans
Natriuresis
Vasoconstriction
Homeostasis
Hemodynamics
Subunit Vaccines
Neoplasms
Cytotoxic T-Lymphocytes
Helper-Inducer T-Lymphocytes
T-Lymphocyte Epitopes
Subunit Vaccines
Interferon-gamma
T-Lymphocytes
Neoplasms
Immunotherapy
Salts
Renin-Angiotensin System
Genes
Sympathetic Nervous System
Genetic Polymorphisms
Adenosine Triphosphate
Lung
Endothelial Cells
Electric Impedance
GTP-Binding Proteins
Subunit Vaccines
Melanoma
Vaccines
T-Lymphocytes
Neoplasms
Natriuresis
Interleukin-6
Pressure
C-Reactive Protein
Genes
Epigenomics
Cardiovascular Diseases
Depression
Methylation
Major Depressive Disorder
Campylobacter jejuni
Virulence
Regulon
Gastroenteritis
Biofilms
Campylobacter jejuni
DNA Methylation
Genes
Orphaned Children
Gastroenteritis
Aldosterone
Hormones
Protein Kinases
Zona Glomerulosa
Phosphotransferases
Blood Vessels
Type 2 Diabetes Mellitus
Indoleamine-Pyrrole 2,3,-Dioxygenase
Arginase
Cytokines

IMMUNOLOGIC MECHANISMS IN LUPUS NEPHRITIS

Madaio, M. P.

National Institutes of Health

1/1/856/30/03

Project: Research project

Lupus Nephritis
Autoantibodies
Antigens
DNA
Surface Antigens

AUTOREACTIVE T CELLS IN MURINE LUPUS NEPHRITIS

Madaio, M. P.

National Institutes of Health

4/1/894/30/97

Project: Research project

Lupus Nephritis
T-Lymphocytes
Immunoglobulins
B-Lymphocytes
Activation Analysis

MOLECULAR ANALYSIS OF HUMAN ANTIGBM ANTIBODIES

Madaio, M. P.

National Institutes of Health

9/1/976/30/06

Project: Research project

Antibodies
Glomerular Basement Membrane
T-Lymphocytes
Clone Cells
Kidney

MOLECULAR MECHANISMS OF RENAL INFLAMMATION AND INJURY

Madaio, M. P., Gasser, D., Cooke, N., Kelly, C., Ziyadeh, F. & Neilson, E.

National Institutes of Health

8/1/927/31/03

Project: Research project

Kidney
Antinuclear Antibodies
Wounds and Injuries
Collagen
Collagen Type IV
Gene Deletion
Proteins
Transgenes
Research Personnel
Genetic Recombination

Regulation of T cell immunity by indol 2,3 dioxygenase

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

4/1/023/31/08

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dioxygenases
Immunity
T-Lymphocytes
Complement Activation

TOLERANCE EVASION BY SELF MHC SPECIFIC T CELLS

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

7/15/985/31/02

Project: Research project

T-Lymphocytes
Peptides
Thymocytes
T-Cell Antigen Receptor
Transgenic Mice

Engineering DNA nanoparticles to create immune tolerance

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

6/15/135/31/17

Project: Research project

Immune Tolerance
Indoleamine-Pyrrole 2,3,-Dioxygenase
Nanoparticles
DNA
Interferons

Manipulating natural host immunoregulation via IDO during viral Infection

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

5/1/094/30/15

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Virus Diseases
T-Lymphocytes
Regulatory T-Lymphocytes
Infection
T-Lymphocytes
Recurrence
Drug Therapy
Neoplasms
Immunity

PROGRAM PROJECT FATTY ACIDS, LIPOPROTEINS &LIPID OXIDAT

Knapp, H., Field, F. J., Chappell, D., Spector, A. & Weintraub, N. L.

National Institutes of Health

9/30/928/31/03

Project: Research project

Coronary Circulation
Blood Vessels
Coronary Vessels
Microvessels
Acids

GENERAL CLINICAL RESEARCH CENTER

Feld, R., Goldberg, M., Naides, S., Anuras, S., Hansen, W., Labrecque, D., Haynes, W., Somers, V., Goldner, W., Ellingrod, V., Williams, R., Schmidt, W., Tsalikian, E. V. A., Schultz, S. K., Corbett, J., Park, G., Dusdieker, L., Mock, D., Damasio, H. C., Ferguson, D., Marcus, M. L., Andreasen, N., Sherman, B., Teresi, M., Lombard, K., Fincham, R., Stanford, W., Chemtob, S., Wolraich, M., Kienzle, M., Feldman, R., Berg, M., Merchant, J., Hoffmann, R., Gingrich, R., Dagle, J., Johnson, S., Sood, A., Schlechte, J. A., Rizzo, M., Block, R., Correia, M., Weiner, G., Link, B., Phillips, B., Lutgendorf, S., Morcuende, J. A., Coryell, W., Stumbo, P., Robillard, J., Noormohamed, S., Hornick, D., Kline, J. N., Carter, A., Bar, R., Schlechte, J. A., Rubinstein, J. T., Bechara, A., Warren, J., Link, B. K., Hayreh, S., Min, D., Phillips, B., Johnson, S., Morcuende, J. A., Thorne, P., Rizzo, M., Lubaroff, D., Wefel, J. S., Sander, M., Widness, J. A., Saltzman, C. L., Wilson, J., Stapleton, J., Yack, H. J., Wallace, R. B., Meier, J., Ahrens, R., Sivitz, W. I., Haynes, W., Stanford, C., England, S. K., Kline, J. N., Strauss, R., Hoffman, E., Murray, J., Moser, D., Levy, S. M., Carter, A. B., Hunninghake, G., Nopoulos, P., Gantz, B., Lutgendorf, S., Paulsen, J., Robinson, R., Timmons, S., Wooldridge, J., Kahn, D. A., Bell, E., Andrews, J. I., Howard, M. A., Ashare, A., Miller, D., Winokur, P., Anderson, B. M., Calarge, C. A., Block, R., Bechara, A., Colaizy, T. T., Beglinger, L., Kleiber, C., Mehra, R., Kreder, K., Morcuende, J. A., Tranel, D. T., Rizzo, M., Correia, M., Williams, R. D., Durairaj, L., Winokur, G., Riggs, C., Madsen, D., Rea, R., Noyes, R., Campbell, K. C. M., Zeitler, R. R., Hayford, J., Stevenson, R., Fitz, A., Schulte, K., Eslinger, P., Strottmann, P., Strottman, P., Burns, C. P., Mulliken, B., Aylward, P., Kisker, T., Cook, B., Laver, R., Cadoret, R., Fick, R., Balough, K., Thompson, H. S., Trigg, M. E., Donohoue, P., Phelps, C., Schwarz, D., Woodhead, J. C., Victor, R., McGuinness, G. A., Richerson, H. B., Abboud, F., Rosenthal, D., Hunsicker, L., Lapolla, J., Schneider, R., Smidt, G., Stegink, L., Rubright, W., Ionasescu, V., B-Chen, W., Joad, J., Ginsberg, B., Weiss, R., Murray, P., Hubel, K., [No Value], V. S., Weismann, D., Burke, P. N., Winniford, M., Weinstein, S., Kummer, M., From, R., Dietz, F., Damasio, A. R., Degowin, R., Tobacman, J., Pruchno, C., Chappell, D., Skorton, D. J., Holmes, C., Lewis, D., Smith, I., Wenzel, R., Dungy, C., Younoszai, M. K., Andersen, B., Callaghan, J., Symreng, T., Winfield, H., Friedlander, M., Syrop, C., Field, E. E., Songsiridej, N., White, C., Runyon, B., Tonner, D., Gupta, S., Worster, D., Thompson, R., Prince, R., Furst, D. E., Platz, C., Brown, J. D., Piette, W., Eckstein, J. W., Clifton, J., Lynch, R. G., Janus, T., Dibona, G., Lawrence, J., Rhead, W., Clamon, G., Stokes, J., Lauer, R., Oren, R., Southard, K., Klepser, M., Carlson, S., Bauman, N. M., Knapp, H., Payne, J., Davis, B., Ault, K., Porter, C., Smetanka, R., Doebbeling, B. N., Ecklund, D., Bertolatus, J. A., Raghuveer, G., Brennan, T. J., Bishop, W., Lawton, W., Loew, T. W., Snetselaar, L., Schlesinger, L. S., Kelch, R., Carter, B., Stanford, R., Bale, J. F., Smith, J., Logan, H., Welsh, M. J., McLennan, G., See, W., Williamson, R., Robinson, S. R., Lopez, J., Wacker, D., Doebbeling, B., Harper, D. C., Schilling, M., Davis, D., Oren, R. M., O'Shaughnessy, P., Heller, K., Choueiri, N., Ferguson, J. S., Dipaola, J., Hocking-Brown, M., Lichtor, J. L., Gardner, S., Dixon, B., Sparks, A., Ernst, M., O'Dorisio, T. M., Keel, P. K., Wacker, D., Damasio, A., Silverman, M., Clamon, G., Ziegler, E., Hunsicker, L. G., Dokras-Jagasia, A., George, T., O'Dorisio, M. S., Snetselaar, L., McLennan, G., Black, D. W., O Leary, D. S., Al-Shaer, M., Degeest, K., Gerday, E., Egri, Z., Cram, P., Schilling, M., Carter, T., McCormick, L., Milchak, R., Segal, N., Doerschug, K., Cobb, D., Shibli-Rahhal, A., Kalil, R., Trask, D., Ringold, V., Schelbert, E., Patel, P., Weintraub, N., Wang, C., Roman, S., Fasano, M., Wolf, B. R., Rossen, J., Doelle, G., Grose, C. F., Horwitz, P., Suneja, M., Peters, T., Dipaola, J., Sheharyar, S., St. Louis, E. K., Lim, V., Vargas, K., Baker, K. M., Mathews, K., Fakhry, A. L. I., Samuel, I., Smith, J., Kennedy, C., Uc, E., Schatteman, G., Dixon, B., Farris, K., Sipe, C., Griffith, T., Rodnitzky, R., Lutz, C. T., Rebouche, C., Burns, C. P., Loening-Baucke, V., Winniford, M., Mummey, C., Segar, J., Heilskov, J., Pillsbury, L., McKay, C., Flanigan, M. J., Soffer, E., Kathol, R. G., Lindgren, S., Rhed, W., Crawford, M., Kline, J. N., McCray, P., Hausberg, M., Anderson, E., Fomon, S., Weinstein, S. L., Tsalikian, E. V. A., Murph, J. R., Bell, E., vangilder, J., George, T., Weinberger, M., Mark, A. L., Donohoue, P., Rossen, J., Johnson, K., Weiler, J., Schrott, H., Saag, K., Dreicer, R., Peterson, M., Ahrens, R., Crowe, R., Hunsicker, L. G., Hoffman, R., Lim, V., Levy, S. M., Kisker, C. T., Hohl, R., Torner, J., Perry, P., Gantz, B., Hegeman, R., Fleckenstein, L., Sivitz, W., Stapleton, J., van Dyke, D., Damasio, A., Hayreh, S., Strauss, R., Min, D., Kao, S., Hunninghake, G., Schwartz, D., Weingeist, T., Widness, J. A., Ziegler, E., Wallace, R. B., La Brecque, D., Zabner, J., Welsh, M. J., Martins, J., Rao, S. S. C. & Rao, S. S. C.

National Institutes of Health

12/1/772/29/08

Project: Research project

Defecation
Fecal Incontinence
Constipation
Healthy Volunteers
Chronic Pain
Defecation
Constipation
Brain
Therapeutics
Laxatives

GENERAL CLINICAL RESEARCH CENTER

Burghen, G., Weber, K., Hak, L., Tylavsky, F., Herrod, H., Christensen, M., Kritchevsky, S., Kutteh, W., Lustig, R., Hathaway, D. K., Buffington, C., Umpierrez, G., Kritchevsky, S., Brown, C., Myers, L. K., Thomason, D., Boucher, B., Hak, E., Satterfield, S., Kutteh, W., Postlethwaite, A., Johnson, K. M., Kitabchi, A. E., Fleckenstein, J., Jones, D., Hathaway, D. K., Wyatt, R., Parker, R., Stentz, F., Alpert, B. S., Collins, R. L., Adkins, R., Wang, B., Tylavsky, F., Kudsk, K., Jacewicz, M., O'Brien, J., Williams, J., Summitt, R., Salim, M., Pfeiffer, R., Tuomanen, E., Meyer, M., McKown, K., Schwab, S., J Hohnson, J., Kraus, A., Mercer, B., Moore, L., K Johnson, K., Kutten, W., Steiner, M. S., Engelhardt, K., Crouse, D., Faulkner, M., Krueger, J. M., Bryer, M., Dockter, M. E., Tuomanen, E., Kotb, M. Y. S., Newman, K., Edwards, N., DeVincenzo, J., Velasquez-Mieyer, P., Dagogo-Jack, S., Ryder, K., Katancik, J., Meyers, L., Debon, M., Rosenberg, W., Stender, S., Riely, C., Casson, P., Kristiansen, S., Egerman, R., Burstein, S., Palmieri, G. M., Rogers, L., Koo, W. W., Burns, R., Carlson, S., Self, T., Bertorini, T., Hughes, T., Deitcher, S., Petrides, A., Sullivan, J., Schoumacher, R., Wyatt, R., Meduri, U., Meyers, L., Waters, B., Johnson, J., Satterfield, S., Gaber, O., Applegate, W., Johnson, K., Burghen, G., Postlethwaite, A., Kitabchi, A., Gaber, A., Meduri, G. U., Alpert, B., Rose, S., Elam, M., Harshfield, G. A., Carbone, L. D. & Carbone, L. D.

National Institutes of Health

12/1/7611/30/09

Project: Research project

pamidronate
Bone and Bones
Research
Blood Pressure
Sodium
Abdominal Aortic Aneurysm
Angiotensin II
Aneurysm
Oxidative Stress
Peroxidase
Endotoxins
Blood Vessels
Atherosclerosis
Inflammation
Hydroxymethylglutaryl-CoA Reductase Inhibitors

SPORE in Prostate Cancer

Young, C., Fatemi, M., Morris, J. C., Thibodeau, S. N., Vile, R., Vasmatzis, G., Jenkins, R. B., Bergstralh, E. J., Cheville, J., Klee, G., Tindall, D. J., Davis, B., Sargent, D., Layton, D., Vuk-Pavlovic, S. & Celis, E.

National Institutes of Health

8/31/018/31/13

Project: Research project

Prostatic Neoplasms
Cytotoxic T-Lymphocytes
Helper-Inducer T-Lymphocytes
Neoplasms
Therapeutics
Cognition
Exercise
Automatic Data Processing
Physical Education and Training
Executive Function
Insulin Resistance
Exercise
Body Composition
Practice Guidelines
African Americans
Prostatic Neoplasms
Cytotoxic T-Lymphocytes
Major Histocompatibility Complex
T-Lymphocyte Epitopes
Antigens
Dendritic Cells
Immunity
Allergy and Immunology
Neoplasms
Cell Biology
Sodium
Cardiovascular Diseases
Hemodynamics
Hormones
Blood Pressure
Epitopes
T-Lymphocyte Epitopes
Cancer Vaccines
Cytotoxic T-Lymphocytes
Cell- and Tissue-Based Therapy
Arousal
Sodium
Hemodynamics
Kidney
Twin Studies

Exercise &Overweight Children's Cognition

McDowell, J., Tomporowski, P., Davis, C. M. & Davis, C. L.

National Institutes of Health

9/5/087/31/15

Project: Research project

Cognition
Exercise
Executive Function
Pediatric Obesity
Research
Glypicans
alpha-Fetoproteins
Hepatocellular Carcinoma
Vaccines
Autoantigens