Projects 1975 2019

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Research project

Mini-plasmin: Pre-Clinical Evaluation of a Novel Thrombolytic Strategy for Stroke

Sazonova, I. Y., Pellock, J., Pellock, J. & Verin, A.

National Institutes of Health

12/7/871/31/15

Project: Research project

Fibrinolysin
Stroke
Tissue Plasminogen Activator
Fibrinolytic Agents
Thrombolytic Therapy

TOLERANCE EVASION BY SELF MHC SPECIFIC T CELLS

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

7/15/985/31/02

Project: Research project

T-Lymphocytes
Peptides
Thymocytes
T-Cell Antigen Receptor
Transgenic Mice

Engineering DNA nanoparticles to create immune tolerance

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

6/15/135/31/17

Project: Research project

Immune Tolerance
Indoleamine-Pyrrole 2,3,-Dioxygenase
Nanoparticles
DNA
Interferons

GLOMERULAR IMMUNE DEPOSIT FORMATION IN SLE

Madaio, M. P.

National Institutes of Health

1/1/8512/31/87

Project: Research project

Systemic Lupus Erythematosus
Immunoglobulins
Lupus Nephritis
Antinuclear Antibodies
Antigen-Antibody Complex
Myeloid Cells
Carcinogenesis
Neoplasms
Inflammation
Kupffer Cells
HLA-G Antigens
Dendritic Cells
Transplantation
Allografts
T-Lymphocytes
African Americans
Sodium
Bone and Bones
Metabolic Bone Diseases
Bone Density
Campylobacter fetus
Virulence Factors
Escherichia coli
S-layer proteins
Antigenic Variation
Natriuresis
Interleukin-6
Pressure
C-Reactive Protein
Genes
Campylobacter jejuni
Campylobacter
Biofilms
Virulence
Regulon
Smoke
Tobacco
Cotinine
Nicotine
Blood Pressure

NCMHD Southeastern Exploratory Sickle Cell Center of Excellence

Adamkiewicz, T., Gibson, R. W., Ikuta, T., Kutlar, A., Gibson, R. W., Gibson, R. W. & Tuan Lo, D.

National Institutes of Health

5/28/0912/31/15

Project: Research project

Sickle Cell Anemia
Hydroxyurea
gamma-Globins
Globins
Opioid Analgesics
African Americans
Tobacco
Living Wills
Tobacco Use
Campylobacter jejuni
DNA Methylation
Genes
Orphaned Children
Gastroenteritis
Adrenergic Receptors
Blood Pressure
Genes
Haplotypes
Vascular Stiffness
DNA Methylation
Psychological Stress
Epigenomics
Health
Substance-Related Disorders
Adenosine Triphosphate
Lung
Endothelial Cells
Electric Impedance
GTP-Binding Proteins
Subunit Vaccines
Interferon-gamma
T-Lymphocytes
Neoplasms
Immunotherapy

GENERAL CLINICAL RESEARCH CENTER

Burghen, G., Weber, K., Hak, L., Tylavsky, F., Herrod, H., Christensen, M., Kritchevsky, S., Kutteh, W., Lustig, R., Hathaway, D. K., Buffington, C., Umpierrez, G., Kritchevsky, S., Brown, C., Myers, L. K., Thomason, D., Boucher, B., Hak, E., Satterfield, S., Kutteh, W., Postlethwaite, A., Johnson, K. M., Kitabchi, A. E., Fleckenstein, J., Jones, D., Hathaway, D. K., Wyatt, R., Parker, R., Stentz, F., Alpert, B. S., Collins, R. L., Adkins, R., Wang, B., Tylavsky, F., Kudsk, K., Jacewicz, M., O'Brien, J., Williams, J., Summitt, R., Salim, M., Pfeiffer, R., Tuomanen, E., Meyer, M., McKown, K., Schwab, S., J Hohnson, J., Kraus, A., Mercer, B., Moore, L., K Johnson, K., Kutten, W., Steiner, M. S., Engelhardt, K., Crouse, D., Faulkner, M., Krueger, J. M., Bryer, M., Dockter, M. E., Tuomanen, E., Kotb, M. Y. S., Newman, K., Edwards, N., DeVincenzo, J., Velasquez-Mieyer, P., Dagogo-Jack, S., Ryder, K., Katancik, J., Meyers, L., Debon, M., Rosenberg, W., Stender, S., Riely, C., Casson, P., Kristiansen, S., Egerman, R., Burstein, S., Palmieri, G. M., Rogers, L., Koo, W. W., Burns, R., Carlson, S., Self, T., Bertorini, T., Hughes, T., Deitcher, S., Petrides, A., Sullivan, J., Schoumacher, R., Wyatt, R., Meduri, U., Meyers, L., Waters, B., Johnson, J., Satterfield, S., Gaber, O., Applegate, W., Johnson, K., Burghen, G., Postlethwaite, A., Kitabchi, A., Gaber, A., Meduri, G. U., Alpert, B., Rose, S., Elam, M., Harshfield, G. A., Carbone, L. D. & Carbone, L. D.

National Institutes of Health

12/1/7611/30/09

Project: Research project

pamidronate
Bone and Bones
Research
Blood Pressure
Sodium
Abdominal Aortic Aneurysm
Angiotensin II
Aneurysm
Oxidative Stress
Peroxidase

IN VIVO STUDIES OF VCAM-1 IN IMMUNITY

Koni, P.

National Institutes of Health

7/1/015/31/07

Project: Research project

Vascular Cell Adhesion Molecule-1
Immunity
T-Lymphocytes
Dendritic Cells
Peripheral Tolerance

PROGRAM PROJECT FATTY ACIDS, LIPOPROTEINS &LIPID OXIDAT

Knapp, H., Field, F. J., Chappell, D., Spector, A. & Weintraub, N. L.

National Institutes of Health

9/30/928/31/03

Project: Research project

Coronary Circulation
Blood Vessels
Coronary Vessels
Microvessels
Acids
Angiotensin II
High Fat Diet
Adipose Tissue
Atherosclerosis
Blood Vessels
Sodium
Cardiovascular Diseases
Hemodynamics
Hormones
Blood Pressure
Acute Lung Injury
Endothelial Cells
Protein Kinase C-alpha
Adenosine
Proteins
Epitopes
T-Lymphocyte Epitopes
Cancer Vaccines
Cytotoxic T-Lymphocytes
Cell- and Tissue-Based Therapy
Calmodulin
Thrombin
Endothelial Cells
Permeability
Myosin-Light-Chain Kinase

Mechanisms of Vascular Dysfunction in Cirrhosis

Khurana, S.

National Institutes of Health

7/28/086/30/14

Project: Research project

Bile Acids and Salts
Gastroenterology
Blood Vessels
Vasodilation
Fibrosis

Stress Related Mechanisms of Hypertension Risk

Gutin, B., Layman, L., Pollock, D., Treiber, F., Pollock, J., Strong, W., Smith, D., George, V., Dong, Y., Kapuku, K. G. & Harshfield, G. A.

National Institutes of Health

7/1/026/30/19

Project: Research project

Hypertension
Renin-Angiotensin System
Natriuresis
Sodium
Biological Assay
Stem Cells
CXCR4 Receptors
Myocardial Ischemia
Myocardium
Cell Survival

Regulation of T cell immunity by indol 2,3 dioxygenase

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

4/1/023/31/08

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dioxygenases
Immunity
T-Lymphocytes
Complement Activation

T CELL IMMUNOREGULATION BY TRYPTOPHAN DEPLETION

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

12/1/983/31/04

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tryptophan
T-Lymphocytes
Embryo Loss
Isoantigens

IMMUNOLOGIC MECHANISMS IN LUPUS NEPHRITIS

Madaio, M. P.

National Institutes of Health

1/1/856/30/03

Project: Research project

Lupus Nephritis
Autoantibodies
Antigens
DNA
Surface Antigens

AUTOREACTIVE T CELLS IN MURINE LUPUS NEPHRITIS

Madaio, M. P.

National Institutes of Health

4/1/894/30/97

Project: Research project

Lupus Nephritis
T-Lymphocytes
Immunoglobulins
B-Lymphocytes
Activation Analysis

MOLECULAR ANALYSIS OF HUMAN ANTIGBM ANTIBODIES

Madaio, M. P.

National Institutes of Health

9/1/976/30/06

Project: Research project

Antibodies
Glomerular Basement Membrane
T-Lymphocytes
Clone Cells
Kidney

MOLECULAR MECHANISMS OF RENAL INFLAMMATION AND INJURY

Madaio, M. P., Gasser, D., Cooke, N., Kelly, C., Ziyadeh, F. & Neilson, E.

National Institutes of Health

8/1/927/31/03

Project: Research project

Kidney
Antinuclear Antibodies
Wounds and Injuries
Collagen
Collagen Type IV
Epigenomics
Type 2 Diabetes Mellitus
Methylation
Cardiovascular Diseases
Obesity
Methylation
Genome
DNA Methylation
Epigenomics
Essential Hypertension
T-Lymphocytes
Recurrence
Drug Therapy
Neoplasms
Immunity
Blood Vessels
Type 2 Diabetes Mellitus
Indoleamine-Pyrrole 2,3,-Dioxygenase
Arginase
Cytokines
Aldosterone
Hormones
Protein Kinases
Zona Glomerulosa
Phosphotransferases
Spinal Cord Diseases
Veterans
Spinal Cord Injuries
Bone Density
Photon Absorptiometry
Campylobacter jejuni
Virulence
Regulon
Gastroenteritis
Biofilms
Cognition
Exercise
Automatic Data Processing
Physical Education and Training
Executive Function
Insulin Resistance
Exercise
Body Composition
Practice Guidelines
African Americans
Catenins
Dendritic Cells
Autoimmune Experimental Encephalomyelitis
Brain
Multiple Sclerosis
hypertension
sodium
single nucleotide polymorphism
genes
salt stress
Epigenomics
Cardiovascular Diseases
Depression
Methylation
Major Depressive Disorder
Molecular Chaperones
Neurodegenerative Diseases
Molecular Probes
Humulus
Metabolic Diseases

VASCULAR MECHANISMS IN ATHEROGENESIS

Lentz, S., Faraci, F., Farci, F., Sigmund, C. D., Heistad, D. & Weintraub, N. L.

National Institutes of Health

6/1/004/30/16

Project: Research project

Surface-Active Agents
Smooth Muscle Myocytes
Pulmonary Surfactant-Associated Protein D
Blood Vessels
Inflammation