Projects 1975 2019

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Research project
Angiotensin II
High Fat Diet
Adipose Tissue
Atherosclerosis
Blood Vessels

TOLERANCE EVASION BY SELF MHC SPECIFIC T CELLS

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

7/15/985/31/02

Project: Research project

T-Lymphocytes
Peptides
Thymocytes
T-Cell Antigen Receptor
Transgenic Mice
Natriuresis
Pressure
Natriuretic Peptides
Sodium
Heart Failure
Blood Vessels
Type 2 Diabetes Mellitus
Indoleamine-Pyrrole 2,3,-Dioxygenase
Arginase
Cytokines
Abdominal Aortic Aneurysm
Angiotensin II
Aneurysm
Oxidative Stress
Peroxidase

Engineering DNA nanoparticles to create immune tolerance

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

6/15/135/31/17

Project: Research project

Immune Tolerance
Indoleamine-Pyrrole 2,3,-Dioxygenase
Nanoparticles
DNA
Interferons

Manipulating natural host immunoregulation via IDO during viral Infection

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

5/1/094/30/15

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Virus Diseases
T-Lymphocytes
Regulatory T-Lymphocytes
Infection

GENERAL CLINICAL RESEARCH CENTER

Burghen, G., Weber, K., Hak, L., Tylavsky, F., Herrod, H., Christensen, M., Kritchevsky, S., Kutteh, W., Lustig, R., Hathaway, D. K., Buffington, C., Umpierrez, G., Kritchevsky, S., Brown, C., Myers, L. K., Thomason, D., Boucher, B., Hak, E., Satterfield, S., Kutteh, W., Postlethwaite, A., Johnson, K. M., Kitabchi, A. E., Fleckenstein, J., Jones, D., Hathaway, D. K., Wyatt, R., Parker, R., Stentz, F., Alpert, B. S., Collins, R. L., Adkins, R., Wang, B., Tylavsky, F., Kudsk, K., Jacewicz, M., O'Brien, J., Williams, J., Summitt, R., Salim, M., Pfeiffer, R., Tuomanen, E., Meyer, M., McKown, K., Schwab, S., J Hohnson, J., Kraus, A., Mercer, B., Moore, L., K Johnson, K., Kutten, W., Steiner, M. S., Engelhardt, K., Crouse, D., Faulkner, M., Krueger, J. M., Bryer, M., Dockter, M. E., Tuomanen, E., Kotb, M. Y. S., Newman, K., Edwards, N., DeVincenzo, J., Velasquez-Mieyer, P., Dagogo-Jack, S., Ryder, K., Katancik, J., Meyers, L., Debon, M., Rosenberg, W., Stender, S., Riely, C., Casson, P., Kristiansen, S., Egerman, R., Burstein, S., Palmieri, G. M., Rogers, L., Koo, W. W., Burns, R., Carlson, S., Self, T., Bertorini, T., Hughes, T., Deitcher, S., Petrides, A., Sullivan, J., Schoumacher, R., Wyatt, R., Meduri, U., Meyers, L., Waters, B., Johnson, J., Satterfield, S., Gaber, O., Applegate, W., Johnson, K., Burghen, G., Postlethwaite, A., Kitabchi, A., Gaber, A., Meduri, G. U., Alpert, B., Rose, S., Elam, M., Harshfield, G. A., Carbone, L. D. & Carbone, L. D.

National Institutes of Health

12/1/7611/30/09

Project: Research project

pamidronate
Bone and Bones
Research
Blood Pressure
Sodium
Nephritis
Antibodies
Pharmaceutical Preparations
Kidney
Glomerulonephritis

RENAL RESEARCH TRAINING PROGRAM

Madaio, M. P., Neilson, E., Turka, L., Agus, Z. & Holzman, L. B.

National Institutes of Health

7/1/756/30/06

Project: Research project

GENERAL CLINICAL RESEARCH CENTER

Mahan, J., Novak, V., Colombo, D., Marucha, P. T., Durnwald, C., Pesavento, T., Corrigan, J., Boudoulas, H., Coyle, J., Cromer, B., Friedman, C., Lima, J., Arnold, M., Wright, J. G., Falko, J. M., Dasta, J., Gerber, N., Leier, C., Lamb, D., Ellison, E. C., Cosio, F., Hartman, J., Grever, M. R., Fabri, P., Zipf, W., Bay, W., Binkley, P. F., Bornstein, R., Allred, J., Snively, T., Cacioppo, J. T., Leenders, N., Pollak, C., Reynolds, N., Glaser, R., Tzagournis, M., Para, M., Rovin, B., Frid, D., West, S., Moser, D., Iams, J., Schwartz, S., Hughes, J., Moore, J. L., Sedmak, D., Rammohan, K., Chan, K., Aman, M. G., Shapiro, C., Lynn, D., Koletar, S., Landon, M., Diaz, P., Carson, W. E., Schuster, D., Snively, T., Cacioppo, J. T., Leenders, N., Pollak, C., Stoney, C., Grecula, J., Lennie, T., Frazier, S. K., Diaz, P., Carson, W. E., Shapiro, C., Para, M. F., Robles, T., Clark, D., Loucks, A., Jackson, R., Schwartz, S., Schuster, D., Kissel, J., Iams, J. A. Y., Paskett, E. D., Emery, C. F., Malarkey, W. B., Aman, M. G., Belury, M., Andersen, B. L., Buckworth, J., Beversdorf, D. Q., Arnold, L. E., Osei, K. N., Habash, D., Ahijevych, K., Mendell, J., Salsberry, P., Diaz, P., Hiremath, L., Rammohan, K., Yee, L., Para, M. F., Elsheikh, B., Lynn, D., Raman, S., Bauer, H., Reiss, R., Reuning, R., vandecreek, L., Wooding-Scott, R., Washington, S., Leiby, J. M., O'Dorisio, S. U. E., Levy, A. B., Wright, F., Panganamala, R., Jaeckle, R., Majetich, N., Nelson, S., Schmidt, H., Kudsk, K., Donnerberg, R. L., Moon, K., Reitz, J., Wooley, C., Warren, L., Mysiw, J., Cataland, S., Caccioppo, J., Ruymann, F., O'Dorisio, T., McNeil, D., O'Dorsio, T., Walson, P., Kraut, E. R., Pearson, A., Schiller, M. R., Greenson, J., Tesi, R., Thomas, F., Benes, S., Herbert, L., Brobeck, E., Foley, M., Flako, J., Schaal, S., Hurley, R., Caldwell, J., O'Dorisio, S., O'Dorisio, M., Quick, D., Bremseth, D., Davis, B., Chang, F., Malarky, W., Marlarkey, W. B., Kiecolt-Glaser, J., Allen, C., Fass, R. J., Tzebiatowski, G., Zuelzer, W., Kolibash, A., Schroeder, K., Starling, R., Carey, L., Nester, T., Hudson, N. P., O'Dorisio, M., Boyne, L., Camisa, C., Visconti, J., Rinehart, J., Sloan, H., MacKichan, J., Hirsch, S., Drake, M., Nahman, N. S., Neidhart, J., Zollinger, R., Strauss, R., Earle, S. B., Bossetti, B., Behrens, B., Balcerzak, S., Rogers, J., Gora, M., Ferguson, R., Kiecolt-Glaser, J., Kang, D., Levy, C., Triozzi, P., McKenna, D., Fish, A., Stout-Shafer, S., Goodman, J., Brugge, K., Whitacre, C., Caligiuri, M., Gilles, E., Burgun, S., Fass, R., Zaqqa, D., Wininger, D., Preshaw, P., Henry, M., Kraut, E., Magorien, R., Sanfilippo, A., Flancbaum, L., Pollack, C., Kirby, T., Souba, W. W., Kang, D., Levy, C., Triozzi, P., McAuley, J., Kiecolt-Glaser, J., Hubble, J., Bates, S., McKenna, D., Fish, A., Stout-Shafer, S., Goodman, J., Caligiuri, M., Porcu, P., Kraut, E., Buck, J., Hall, C., Kaumaya, P. T., Wininger, D., Lin, T., Smith, A., Nash, S., Hoffman, R., Medeiros, L., Marcucci, G., Fristad, M., Haines, D., Pajer, K., Corwin, E., Mastronarde, J., Grzybowski, D., Wininger, D., Kirby, T. I. M., Roe, B., Shneker, B., Racke, M., Hawker, K. S., Borchers, J., Rajab, A., Parthasarathy, S., Paulson, G., Hebert, L. A., Kiecolt-Glaser, J. A. N., Disilvestro, R., Nahman, S., Ehrman, J., Jhiang, S., Sharma, H., Engebretson, T., Schwartzbaum, J., Boyle, J., Berntson, G. G., Stone, K. S., Sotos, J., Kien, C. L., Mazzaferri, E., McAuley, J., Schirmer, W., Kissel, J., Cottrell, D., Loucks, A., Mendell, J., Wewers, M. E., Hebert, L., Andersen, B., Gadek, J., Jackson, R. D., Stoney, C., Matkovic, V., Ahijevych, K., Malarkey, W. B., Osei, K., Davis, W. B. & Nahman, N. S.

National Institutes of Health

12/1/7611/30/09

Project: Research project

Research Personnel
Vitamin E
Cystic Fibrosis
Tobacco Products
Respiratory System
African Americans
Sodium
Bone and Bones
Metabolic Bone Diseases
Bone Density
T-Lymphocytes
Recurrence
Drug Therapy
Neoplasms
Immunity
Calmodulin
Thrombin
Endothelial Cells
Permeability
Myosin-Light-Chain Kinase
Aldosterone
Hormones
Protein Kinases
Zona Glomerulosa
Phosphotransferases

GENERAL CLINICAL RESEARCH CENTER

Feld, R., Goldberg, M., Naides, S., Anuras, S., Hansen, W., Labrecque, D., Haynes, W., Somers, V., Goldner, W., Ellingrod, V., Williams, R., Schmidt, W., Tsalikian, E. V. A., Schultz, S. K., Corbett, J., Park, G., Dusdieker, L., Mock, D., Damasio, H. C., Ferguson, D., Marcus, M. L., Andreasen, N., Sherman, B., Teresi, M., Lombard, K., Fincham, R., Stanford, W., Chemtob, S., Wolraich, M., Kienzle, M., Feldman, R., Berg, M., Merchant, J., Hoffmann, R., Gingrich, R., Dagle, J., Johnson, S., Sood, A., Schlechte, J. A., Rizzo, M., Block, R., Correia, M., Weiner, G., Link, B., Phillips, B., Lutgendorf, S., Morcuende, J. A., Coryell, W., Stumbo, P., Robillard, J., Noormohamed, S., Hornick, D., Kline, J. N., Carter, A., Bar, R., Schlechte, J. A., Rubinstein, J. T., Bechara, A., Warren, J., Link, B. K., Hayreh, S., Min, D., Phillips, B., Johnson, S., Morcuende, J. A., Thorne, P., Rizzo, M., Lubaroff, D., Wefel, J. S., Sander, M., Widness, J. A., Saltzman, C. L., Wilson, J., Stapleton, J., Yack, H. J., Wallace, R. B., Meier, J., Ahrens, R., Sivitz, W. I., Haynes, W., Stanford, C., England, S. K., Kline, J. N., Strauss, R., Hoffman, E., Murray, J., Moser, D., Levy, S. M., Carter, A. B., Hunninghake, G., Nopoulos, P., Gantz, B., Lutgendorf, S., Paulsen, J., Robinson, R., Timmons, S., Wooldridge, J., Kahn, D. A., Bell, E., Andrews, J. I., Howard, M. A., Ashare, A., Miller, D., Winokur, P., Anderson, B. M., Calarge, C. A., Block, R., Bechara, A., Colaizy, T. T., Beglinger, L., Kleiber, C., Mehra, R., Kreder, K., Morcuende, J. A., Tranel, D. T., Rizzo, M., Correia, M., Williams, R. D., Durairaj, L., Winokur, G., Riggs, C., Madsen, D., Rea, R., Noyes, R., Campbell, K. C. M., Zeitler, R. R., Hayford, J., Stevenson, R., Fitz, A., Schulte, K., Eslinger, P., Strottmann, P., Strottman, P., Burns, C. P., Mulliken, B., Aylward, P., Kisker, T., Cook, B., Laver, R., Cadoret, R., Fick, R., Balough, K., Thompson, H. S., Trigg, M. E., Donohoue, P., Phelps, C., Schwarz, D., Woodhead, J. C., Victor, R., McGuinness, G. A., Richerson, H. B., Abboud, F., Rosenthal, D., Hunsicker, L., Lapolla, J., Schneider, R., Smidt, G., Stegink, L., Rubright, W., Ionasescu, V., B-Chen, W., Joad, J., Ginsberg, B., Weiss, R., Murray, P., Hubel, K., [No Value], V. S., Weismann, D., Burke, P. N., Winniford, M., Weinstein, S., Kummer, M., From, R., Dietz, F., Damasio, A. R., Degowin, R., Tobacman, J., Pruchno, C., Chappell, D., Skorton, D. J., Holmes, C., Lewis, D., Smith, I., Wenzel, R., Dungy, C., Younoszai, M. K., Andersen, B., Callaghan, J., Symreng, T., Winfield, H., Friedlander, M., Syrop, C., Field, E. E., Songsiridej, N., White, C., Runyon, B., Tonner, D., Gupta, S., Worster, D., Thompson, R., Prince, R., Furst, D. E., Platz, C., Brown, J. D., Piette, W., Eckstein, J. W., Clifton, J., Lynch, R. G., Janus, T., Dibona, G., Lawrence, J., Rhead, W., Clamon, G., Stokes, J., Lauer, R., Oren, R., Southard, K., Klepser, M., Carlson, S., Bauman, N. M., Knapp, H., Payne, J., Davis, B., Ault, K., Porter, C., Smetanka, R., Doebbeling, B. N., Ecklund, D., Bertolatus, J. A., Raghuveer, G., Brennan, T. J., Bishop, W., Lawton, W., Loew, T. W., Snetselaar, L., Schlesinger, L. S., Kelch, R., Carter, B., Stanford, R., Bale, J. F., Smith, J., Logan, H., Welsh, M. J., McLennan, G., See, W., Williamson, R., Robinson, S. R., Lopez, J., Wacker, D., Doebbeling, B., Harper, D. C., Schilling, M., Davis, D., Oren, R. M., O'Shaughnessy, P., Heller, K., Choueiri, N., Ferguson, J. S., Dipaola, J., Hocking-Brown, M., Lichtor, J. L., Gardner, S., Dixon, B., Sparks, A., Ernst, M., O'Dorisio, T. M., Keel, P. K., Wacker, D., Damasio, A., Silverman, M., Clamon, G., Ziegler, E., Hunsicker, L. G., Dokras-Jagasia, A., George, T., O'Dorisio, M. S., Snetselaar, L., McLennan, G., Black, D. W., O Leary, D. S., Al-Shaer, M., Degeest, K., Gerday, E., Egri, Z., Cram, P., Schilling, M., Carter, T., McCormick, L., Milchak, R., Segal, N., Doerschug, K., Cobb, D., Shibli-Rahhal, A., Kalil, R., Trask, D., Ringold, V., Schelbert, E., Patel, P., Weintraub, N., Wang, C., Roman, S., Fasano, M., Wolf, B. R., Rossen, J., Doelle, G., Grose, C. F., Horwitz, P., Suneja, M., Peters, T., Dipaola, J., Sheharyar, S., St. Louis, E. K., Lim, V., Vargas, K., Baker, K. M., Mathews, K., Fakhry, A. L. I., Samuel, I., Smith, J., Kennedy, C., Uc, E., Schatteman, G., Dixon, B., Farris, K., Sipe, C., Griffith, T., Rodnitzky, R., Lutz, C. T., Rebouche, C., Burns, C. P., Loening-Baucke, V., Winniford, M., Mummey, C., Segar, J., Heilskov, J., Pillsbury, L., McKay, C., Flanigan, M. J., Soffer, E., Kathol, R. G., Lindgren, S., Rhed, W., Crawford, M., Kline, J. N., McCray, P., Hausberg, M., Anderson, E., Fomon, S., Weinstein, S. L., Tsalikian, E. V. A., Murph, J. R., Bell, E., vangilder, J., George, T., Weinberger, M., Mark, A. L., Donohoue, P., Rossen, J., Johnson, K., Weiler, J., Schrott, H., Saag, K., Dreicer, R., Peterson, M., Ahrens, R., Crowe, R., Hunsicker, L. G., Hoffman, R., Lim, V., Levy, S. M., Kisker, C. T., Hohl, R., Torner, J., Perry, P., Gantz, B., Hegeman, R., Fleckenstein, L., Sivitz, W., Stapleton, J., van Dyke, D., Damasio, A., Hayreh, S., Strauss, R., Min, D., Kao, S., Hunninghake, G., Schwartz, D., Weingeist, T., Widness, J. A., Ziegler, E., Wallace, R. B., La Brecque, D., Zabner, J., Welsh, M. J., Martins, J., Rao, S. S. C. & Rao, S. S. C.

National Institutes of Health

12/1/772/29/08

Project: Research project

Defecation
Fecal Incontinence
Constipation
Healthy Volunteers
Chronic Pain
Bone and Bones
Food
Mesenchymal Stromal Cells
Stem Cells
Leptin
Microtubules
Endothelial Cells
Lung
Thrombin
Phosphorylation
African Americans
Natriuresis
Vasoconstriction
Homeostasis
Hemodynamics
Campylobacter jejuni
Campylobacter
Biofilms
Virulence
Regulon
Subunit Vaccines
Interferon-gamma
T-Lymphocytes
Neoplasms
Immunotherapy
Subunit Vaccines
Neoplasms
Cytotoxic T-Lymphocytes
Helper-Inducer T-Lymphocytes
T-Lymphocyte Epitopes
Salts
Renin-Angiotensin System
Genes
Sympathetic Nervous System
Genetic Polymorphisms
Campylobacter jejuni
Membrane Proteins
Vaccines
Campylobacter Infections
Immunity
Arousal
Sodium
Hemodynamics
Kidney
Twin Studies
Blood Pressure
Kidney
Salts
Sodium
Research
Campylobacter jejuni
Virulence
Regulon
Gastroenteritis
Biofilms

Exercise &Overweight Children's Cognition

McDowell, J., Tomporowski, P., Davis, C. M. & Davis, C. L.

National Institutes of Health

9/5/087/31/15

Project: Research project

Cognition
Exercise
Executive Function
Pediatric Obesity
Research
Dendritic Cells
Immunity
Allergy and Immunology
Neoplasms
Cell Biology
Catenins
Dendritic Cells
Autoimmune Experimental Encephalomyelitis
Brain
Multiple Sclerosis
Catenins
beta Catenin
Dendritic Cells
Inflammation
Inflammatory Bowel Diseases
Hormones
Placental Lactogen
Lactotrophs
Pituitary Hormones
Pituitary Neoplasms
Epigenomics
Cardiovascular Diseases
Depression
Methylation
Major Depressive Disorder

T CELL IMMUNOREGULATION BY TRYPTOPHAN DEPLETION

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

12/1/983/31/04

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tryptophan
T-Lymphocytes
Embryo Loss
Isoantigens
Natriuresis
Interleukin-6
Pressure
C-Reactive Protein
Genes

T cell regulation by IDO-competent plasmacytoid dendritic cells

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

5/22/094/30/12

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
T-Lymphocytes
Islets of Langerhans
Inflammation
Epigenomics
Type 2 Diabetes Mellitus
Methylation
Cardiovascular Diseases
Obesity
Heart Rate
Genes
Cardiovascular Diseases
Genetic Databases
Twin Studies

Stress Related Mechanisms of Hypertension Risk

Gutin, B., Layman, L., Pollock, D., Treiber, F., Pollock, J., Strong, W., Smith, D., George, V., Dong, Y., Kapuku, K. G. & Harshfield, G. A.

National Institutes of Health

7/1/026/30/19

Project: Research project

Hypertension
Renin-Angiotensin System
Natriuresis
Sodium
Biological Assay

IDO dependent T cell suppression

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

12/1/0411/30/10

Project: Research project

T-Lymphocytes
Allografts
Immunity
Cell Proliferation
Indoleamine-Pyrrole 2,3,-Dioxygenase
hypertension
sodium
single nucleotide polymorphism
genes
salt stress

The Role of Endothelin-1 in Sickle Cell Disease

Meiler, S., Pollock, D. & Kutlar, A.

National Institutes of Health

8/15/135/31/18

Project: Research project

Sickle Cell Anemia
Endothelin-1
Translational Medical Research
Research
Pain

NCMHD Southeastern Exploratory Sickle Cell Center of Excellence

Adamkiewicz, T., Gibson, R. W., Ikuta, T., Kutlar, A., Gibson, R. W., Gibson, R. W. & Tuan Lo, D.

National Institutes of Health

5/28/0912/31/15

Project: Research project

Sickle Cell Anemia
Hydroxyurea
gamma-Globins
Globins
Opioid Analgesics