Projects 1975 2019

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Research project

Mini-plasmin: Pre-Clinical Evaluation of a Novel Thrombolytic Strategy for Stroke

Sazonova, I. Y., Pellock, J., Pellock, J. & Verin, A.

National Institutes of Health

12/7/871/31/15

Project: Research project

Fibrinolysin
Stroke
Tissue Plasminogen Activator
Fibrinolytic Agents
Thrombolytic Therapy

TOLERANCE EVASION BY SELF MHC SPECIFIC T CELLS

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

7/15/985/31/02

Project: Research project

T-Lymphocytes
Peptides
Thymocytes
T-Cell Antigen Receptor
Transgenic Mice

Engineering DNA nanoparticles to create immune tolerance

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

6/15/135/31/17

Project: Research project

Immune Tolerance
Indoleamine-Pyrrole 2,3,-Dioxygenase
Nanoparticles
DNA
Interferons

GLOMERULAR IMMUNE DEPOSIT FORMATION IN SLE

Madaio, M. P.

National Institutes of Health

1/1/8512/31/87

Project: Research project

Systemic Lupus Erythematosus
Immunoglobulins
Lupus Nephritis
Antinuclear Antibodies
Antigen-Antibody Complex

IN VIVO STUDIES OF VCAM-1 IN IMMUNITY

Koni, P.

National Institutes of Health

7/1/015/31/07

Project: Research project

Vascular Cell Adhesion Molecule-1
Immunity
T-Lymphocytes
Dendritic Cells
Peripheral Tolerance

Mechanisms of Vascular Dysfunction in Cirrhosis

Khurana, S.

National Institutes of Health

7/28/086/30/14

Project: Research project

Bile Acids and Salts
Gastroenterology
Blood Vessels
Vasodilation
Fibrosis
HLA-G Antigens
Dendritic Cells
Transplantation
Allografts
T-Lymphocytes
Blood Vessels
Type 2 Diabetes Mellitus
Indoleamine-Pyrrole 2,3,-Dioxygenase
Arginase
Cytokines
Nephritis
Podocytes
Peptides
Glomerulonephritis
Endothelial Cells

MOLECULAR REGULATION OF ENDOTHELIAL CELL PERMEABILITY

Langan, G. P., Ratneshwar, L., Garcia, J. G. N., Birukov, K., Natarajan, V., Salgia, R., English, D. K., Patterson, C., Romer, L., Crow, M. T., Hassoun, P. & Verin, A. D.

National Institutes of Health

2/1/981/31/14

Project: Research project

Microtubules
Lung
Endothelial Cells
Permeability
Myosin Light Chains
Defecation
Constipation
Brain
Therapeutics
Laxatives

GENERAL CLINICAL RESEARCH CENTER

Burghen, G., Weber, K., Hak, L., Tylavsky, F., Herrod, H., Christensen, M., Kritchevsky, S., Kutteh, W., Lustig, R., Hathaway, D. K., Buffington, C., Umpierrez, G., Kritchevsky, S., Brown, C., Myers, L. K., Thomason, D., Boucher, B., Hak, E., Satterfield, S., Kutteh, W., Postlethwaite, A., Johnson, K. M., Kitabchi, A. E., Fleckenstein, J., Jones, D., Hathaway, D. K., Wyatt, R., Parker, R., Stentz, F., Alpert, B. S., Collins, R. L., Adkins, R., Wang, B., Tylavsky, F., Kudsk, K., Jacewicz, M., O'Brien, J., Williams, J., Summitt, R., Salim, M., Pfeiffer, R., Tuomanen, E., Meyer, M., McKown, K., Schwab, S., J Hohnson, J., Kraus, A., Mercer, B., Moore, L., K Johnson, K., Kutten, W., Steiner, M. S., Engelhardt, K., Crouse, D., Faulkner, M., Krueger, J. M., Bryer, M., Dockter, M. E., Tuomanen, E., Kotb, M. Y. S., Newman, K., Edwards, N., DeVincenzo, J., Velasquez-Mieyer, P., Dagogo-Jack, S., Ryder, K., Katancik, J., Meyers, L., Debon, M., Rosenberg, W., Stender, S., Riely, C., Casson, P., Kristiansen, S., Egerman, R., Burstein, S., Palmieri, G. M., Rogers, L., Koo, W. W., Burns, R., Carlson, S., Self, T., Bertorini, T., Hughes, T., Deitcher, S., Petrides, A., Sullivan, J., Schoumacher, R., Wyatt, R., Meduri, U., Meyers, L., Waters, B., Johnson, J., Satterfield, S., Gaber, O., Applegate, W., Johnson, K., Burghen, G., Postlethwaite, A., Kitabchi, A., Gaber, A., Meduri, G. U., Alpert, B., Rose, S., Elam, M., Harshfield, G. A., Carbone, L. D. & Carbone, L. D.

National Institutes of Health

12/1/7611/30/09

Project: Research project

pamidronate
Bone and Bones
Research
Blood Pressure
Sodium

SPORE in Prostate Cancer

Young, C., Fatemi, M., Morris, J. C., Thibodeau, S. N., Vile, R., Vasmatzis, G., Jenkins, R. B., Bergstralh, E. J., Cheville, J., Klee, G., Tindall, D. J., Davis, B., Sargent, D., Layton, D., Vuk-Pavlovic, S. & Celis, E.

National Institutes of Health

8/31/018/31/13

Project: Research project

Prostatic Neoplasms
Cytotoxic T-Lymphocytes
Helper-Inducer T-Lymphocytes
Neoplasms
Therapeutics
Cytotoxic T-Lymphocytes
Prostatic Neoplasms
Vaccines
T-Lymphocyte Epitopes
Immunotherapy
Fecal Incontinence
Therapeutics
Lower Gastrointestinal Tract
Pelvic Floor
Muscle Strength
Epitopes
T-Lymphocyte Epitopes
Cancer Vaccines
Cytotoxic T-Lymphocytes
Cell- and Tissue-Based Therapy
Abdominal Aortic Aneurysm
Angiotensin II
Aneurysm
Oxidative Stress
Peroxidase
Stem Cells
CXCR4 Receptors
Myocardial Ischemia
Myocardium
Cell Survival

VACCINE TO TREAT CHRONIC HEPATITIS B VIRUS INFECTION

Vitello, M., Chesnut, R. & Celis, E.

National Institutes of Health

4/1/924/30/97

Project: Research project

Cytotoxic T-Lymphocytes
Hepatitis B virus
Vaccines
T-Lymphocyte Epitopes
Chronic Hepatitis B
Natriuresis
Interleukin-6
Pressure
C-Reactive Protein
Genes
Campylobacter fetus
Virulence Factors
Escherichia coli
S-layer proteins
Antigenic Variation
Campylobacter jejuni
Proteins
Temperature
Poultry
Gastroenteritis
Sodium
Cardiovascular Diseases
Hemodynamics
Hormones
Blood Pressure
Cognition
Exercise
Automatic Data Processing
Physical Education and Training
Executive Function
Immunity
Immunization
T-Lymphocytes
Antigen Presentation
Immunotherapy
hypertension
sodium
single nucleotide polymorphism
genes
salt stress
Campylobacter jejuni
DNA Methylation
Genes
Orphaned Children
Gastroenteritis
Natriuresis
Pressure
Natriuretic Peptides
Sodium
Heart Failure

Regulation of T cell immunity by indol 2,3 dioxygenase

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

4/1/023/31/08

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dioxygenases
Immunity
T-Lymphocytes
Complement Activation

T CELL IMMUNOREGULATION BY TRYPTOPHAN DEPLETION

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

12/1/983/31/04

Project: Research project

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tryptophan
T-Lymphocytes
Embryo Loss
Isoantigens

IMMUNOLOGIC MECHANISMS IN LUPUS NEPHRITIS

Madaio, M. P.

National Institutes of Health

1/1/856/30/03

Project: Research project

Lupus Nephritis
Autoantibodies
Antigens
DNA
Surface Antigens

AUTOREACTIVE T CELLS IN MURINE LUPUS NEPHRITIS

Madaio, M. P.

National Institutes of Health

4/1/894/30/97

Project: Research project

Lupus Nephritis
T-Lymphocytes
Immunoglobulins
B-Lymphocytes
Activation Analysis

MOLECULAR ANALYSIS OF HUMAN ANTIGBM ANTIBODIES

Madaio, M. P.

National Institutes of Health

9/1/976/30/06

Project: Research project

Antibodies
Glomerular Basement Membrane
T-Lymphocytes
Clone Cells
Kidney

MOLECULAR MECHANISMS OF RENAL INFLAMMATION AND INJURY

Madaio, M. P., Gasser, D., Cooke, N., Kelly, C., Ziyadeh, F. & Neilson, E.

National Institutes of Health

8/1/927/31/03

Project: Research project

Kidney
Antinuclear Antibodies
Wounds and Injuries
Collagen
Collagen Type IV
Gene Deletion
Proteins
Transgenes
Research Personnel
Genetic Recombination
Methylation
Genome
DNA Methylation
Epigenomics
Essential Hypertension
Myeloid Cells
Carcinogenesis
Neoplasms
Inflammation
Kupffer Cells
Heart Rate
Genes
Cardiovascular Diseases
Genetic Databases
Twin Studies
Acute Lung Injury
Endothelial Cells
Protein Kinase C-alpha
Adenosine
Proteins
Adenosine Triphosphate
Lung
Endothelial Cells
Electric Impedance
GTP-Binding Proteins

PROGRAM PROJECT FATTY ACIDS, LIPOPROTEINS &LIPID OXIDAT

Knapp, H., Field, F. J., Chappell, D., Spector, A. & Weintraub, N. L.

National Institutes of Health

9/30/928/31/03

Project: Research project

Coronary Circulation
Blood Vessels
Coronary Vessels
Microvessels
Acids
Spinal Cord Diseases
Veterans
Spinal Cord Injuries
Bone Density
Photon Absorptiometry
Gastric Inhibitory Polypeptide
Bone Remodeling
Bone and Bones
Bone Resorption
Peptide Receptors
Prostatic Neoplasms
Cytotoxic T-Lymphocytes
Major Histocompatibility Complex
T-Lymphocyte Epitopes
Antigens
rural community
nicotine
morbidity
mortality
school system
Transforming Growth Factor beta
Permeability
Endothelial Cells
p38 Mitogen-Activated Protein Kinases
Electric Impedance
Angiotensin II
High Fat Diet
Adipose Tissue
Atherosclerosis
Blood Vessels
Insulin Resistance
Exercise
Body Composition
Practice Guidelines
African Americans
Smoke
Tobacco
Cotinine
Nicotine
Blood Pressure