Research Output

2017

A phase 1b/2b multicenter study of oral panobinostat plus azacitidine in adults with MDS, CMML or AML with ≤30% blasts

Garcia-Manero, G., Sekeres, M. A., Egyed, M., Breccia, M., Graux, C., Cavenagh, J. D., Salman, H., Illes, A., Fenaux, P., Deangelo, D. J., Stauder, R., Yee, K., Zhu, N., Lee, J. H., Valcarcel, D., Macwhannell, A., Borbenyi, Z., Gazi, L., Acharyya, S., Ide, S. & 2 others, Marker, M. & Ottmann, O. G., Jan 1 2017, In : Leukemia. 31, 12, p. 2799-2806 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

A randomized trial to reduce disparities in referral for transplant evaluation

Patzer, R. E., Paul, S., Plantinga, L., Gander, J., Sauls, L., Krisher, J., Mulloy, L. L., Gibney, E. M., Browne, T., Zayas, C. F., Mcclellan, W. M., Arriola, K. J. & Pastan, S. O., Mar 2017, In : Journal of the American Society of Nephrology. 28, 3, p. 935-942 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Are EETs at the heart of the b“EET” in obesity-induced cardiomyopathy?

Dellsperger, K. C., Aug 11 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 313, 2, p. H326-H327

Research output: Contribution to journalEditorial

A single bout of maximal exercise improves lung function in patients with cystic fibrosis

Tucker, M. A., Crandall, R., Seigler, N., Rodriguez-Miguelez, P., McKie, K. T., Forseen, C., Thomas, J. & Harris, R. A., Nov 2017, In : Journal of Cystic Fibrosis. 16, 6, p. 752-758 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Assessing genetic risk of hypertension at an early age: future research directions

Wang, X. & Snieder, H., Nov 2 2017, In : Expert Review of Cardiovascular Therapy. 15, 11, p. 809-812 4 p.

Research output: Contribution to journalEditorial

Association of DPP-4 activity with BMD, body composition, and incident hip fracture: the Cardiovascular Health Study

Carbone, L. D., Bůžková, P., Fink, H. A., Robbins, J. A., Bethel, M., Isales, C. M. & Hill, W. D., May 1 2017, In : Osteoporosis International. 28, 5, p. 1631-1640 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Association of Plasma SDF-1 with Bone Mineral Density, Body Composition, and Hip Fractures in Older Adults: The Cardiovascular Health Study

Carbone, L. D., Bůžková, P., Fink, H. A., Robbins, J. A., Bethel, M., Hamrick, M. W. & Hill, W. D., Jun 1 2017, In : Calcified Tissue International. 100, 6, p. 599-608 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Associations of Biomarker-Calibrated Sodium and Potassium Intakes with Cardiovascular Disease Risk among Postmenopausal Women

Prentice, R. L., Huang, Y., Neuhouser, M. L., Manson, J. E., Mossavar-Rahmani, Y., Thomas, F., Tinker, L. F., Allison, M., Johnson, K. C., Wassertheil-Smoller, S., Seth, A., Rossouw, J. E., Shikany, J., Carbone, L. D., Martin, L. W., Stefanick, M. L., Haring, B. & Van Horn, L., Nov 1 2017, In : American journal of epidemiology. 186, 9, p. 1035-1043 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Augmented expression of polo-like kinase 1 indicates poor clinical outcome for breast patients: A systematic review and meta-analysis

Zhang, Y., Wu, Z., Liu, D., Wang, M., Xiao, G., Wang, P., Sun, X., Ren, H., Tang, S-C. & Du, N., Jan 1 2017, In : Oncotarget. 8, 34, p. 57723-57732 10 p.

Research output: Contribution to journalReview article

6 Scopus citations

Autoimmune progesterone dermatitis manifesting as mucosal erythema multiforme in the setting of HIV infection

Grunnet, K. M., Powell, K. S., Miller, I. A. & Davis, L. S., Jan 1 2017, In : JAAD Case Reports. 3, 1, p. 22-24 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Autophagy is activated to protect against podocyte injury in adriamycin-induced nephropathy

Yi, M., Zhang, L., Liu, Y., Livingston, M. J., Chen, J., Nahman, N. S., Liu, F. & Dong, Z., Jan 1 2017, In : American Journal of Physiology - Renal Physiology. 313, 1, p. F74-F84

Research output: Contribution to journalArticle

16 Scopus citations

A whole brain volumetric approach in overweight/obese children: Examining the association with different physical fitness components and academic performance. The ActiveBrains project

Esteban-Cornejo, I., Cadenas-Sanchez, C., Contreras-Rodriguez, O., Verdejo-Roman, J., Mora-Gonzalez, J., Migueles, J. H., Henriksson, P., Davis, C. L., Verdejo-Garcia, A., Catena, A. & Ortega, F. B., Oct 1 2017, In : NeuroImage. 159, p. 346-354 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Basolateral delivery of the type i transforming growth factor beta receptor is mediated by a dominant-acting cytoplasmic motif

Yin, X., Kang, J. H., Andrianifahanana, M., Wang, Y., Jung, M. Y., Hernandez, D. M. & Leof, E. B., Oct 1 2017, In : Molecular Biology of the Cell. 28, 20, p. 2701-2711 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Berberine regulates the protein expression of multiple tumorigenesis-related genes in hepatocellular carcinoma cell lines

Chuang, T. Y., Wu, H. L., Min, J., Diamond, M. P., Azziz, R. & Chen, Y-H., May 30 2017, In : Cancer Cell International. 17, 1, 59.

Research output: Contribution to journalArticle

11 Scopus citations

Biased g protein-coupled receptor signaling: New player in modulating physiology and pathology

Bologna, Z., Teoh, J. P., Bayoumi, A. S., Tang, Y. & Kim, I. M., Jan 2017, In : Biomolecules and Therapeutics. 25, 1, p. 12-25 14 p.

Research output: Contribution to journalArticle

43 Scopus citations

Blepharochalasis: something to cry about

Browning, R. J., Sanchez, A. T., Mullins, S., Sheehan, D. J. & Davis, L. S., Mar 1 2017, In : Journal of Cutaneous Pathology. 44, 3, p. 279-282 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Blood pressure trajectories from childhood to young adulthood associated with cardiovascular risk

Hao, G., Wang, X., Treiber, F. A., Harshfield, G., Kapuku, G. & Su, S., Mar 1 2017, In : Hypertension. 69, 3, p. 435-442 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Bone mineral density and risk of heart failure in older adults: The cardiovascular health study

Fohtung, R. B., Brown, D. L., Koh, W. J. H., Bartz, T. M., Carbone, L. D., Civitelli, R., Stein, P. K., Chaves, P. H. M., Kestenbaum, B. R. & Kizer, J. R., Jan 1 2017, In : Journal of the American Heart Association. 6, 3, e004344.

Research output: Contribution to journalArticle

9 Scopus citations

Cancer immunotherapy: moving forward with peptide T cell vaccines

Kumai, T., Fan, A., Harabuchi, Y. & Celis, E., Aug 2017, In : Current Opinion in Immunology. 47, p. 57-63 7 p.

Research output: Contribution to journalReview article

23 Scopus citations

Can Locoregionally Recurrent Breast Cancer Be Cured?

Chand, A. R., Ziauddin, M. F. & Tang, S. C., Aug 2017, In : Clinical Breast Cancer. 17, 5, p. 326-335 10 p.

Research output: Contribution to journalReview article

7 Scopus citations

Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity

Zhu, H., Lemos, H., Bhatt, B., Islam, B. N., Singh, A., Gurav, A., Huang, L., Browning, D. D., Mellor, A., Fulzele, S. & Singh, N., Sep 2017, In : PloS one. 12, 9, e0183484.

Research output: Contribution to journalArticle

8 Scopus citations

Cardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy

Li, J., Ma, W., Yue, G., Tang, Y., Kim, I. M., Weintraub, N. L., Wang, X. & Su, H., Jan 1 2017, In : Journal of molecular and cellular cardiology. 102, p. 53-60 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Cardiovascular catheter with an expandable origami structure

Taylor, A. J., Chen, Y., Fok, M., Berman, A., Nilsson, K. & Tse, Z. T. H., Sep 1 2017, In : Journal of Medical Devices, Transactions of the ASME. 11, 3, 034505.

Research output: Contribution to journalArticle

1 Scopus citations

Case-based approach to demonstrate utility of cardiac magnetic resonance imaging (MRI) for planning biventricular repair with inconclusive echo: Illustration of two cases

Gupta, S., Li, H., Keshavamurthy, J. H., Sharma, G. K. & Polimenakos, A. C., Dec 1 2017, In : Quantitative Imaging in Medicine and Surgery. 7, 6, p. 732-735 4 p.

Research output: Contribution to journalLetter

1 Scopus citations

cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium

Wang, R., Islam, B. N., Bridges, A., Sharman, S. K., Hu, M., Hou, Y., Somanath, P. R., Venable, L., Singh, N., Kim, S., Sridhar, S., Hofmann, F. & Browning, D. D., Feb 1 2017, In : American Journal of Pathology. 187, 2, p. 377-389 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy

Burgert, A., Schlegel, J., Bécam, J., Doose, S., Bieberich, E., Schubert-Unkmeir, A. & Sauer, M., Jan 1 2017, In : Angewandte Chemie - International Edition. 56, 22, p. 6131-6135 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Characterization of pressure-mediated vascular tone in resistance arteries from bile duct-ligated rats

Jadeja, R. N., Thounaojam, M. C. & Khurana, S., Jan 1 2017, In : Oncotarget. 8, 19, p. 30706-30722 17 p.

Research output: Contribution to journalArticle

3 Scopus citations

Chemo-immunotherapy: Role of indoleamine 2,3-dioxygenase in defining immunogenic versus tolerogenic cell death in the tumor microenvironment

Johnson, T. S., Mcgaha, T. & Munn, D. H., Jan 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 91-104 14 p. (Advances in Experimental Medicine and Biology; vol. 1036).

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations

Chronic constipation

Camilleri, M., Ford, A. C., Mawe, G. M., Dinning, P. G., Rao, S. S. C., Chey, W. D., Simrén, M., Lembo, A., Young-Fadok, T. M. & Chang, L., Dec 14 2017, In : Nature Reviews Disease Primers. 3, 17095.

Research output: Contribution to journalReview article

47 Scopus citations

Clinical and pathological characteristics of HIV-and HHV-8-negative Castleman disease

Yu, L., Tu, M., Cortes, J., Xu-Monette, Z. Y., Miranda, R. N., Zhang, J., Orlowski, R. Z., Neelapu, S., Boddu, P. C., Akosile, M. A., Uldrick, T. S., Yarchoan, R., Medeiros, L. J., Li, Y., Fajgenbaum, D. C. & Young, K. H., Mar 23 2017, In : Blood. 129, 12, p. 1658-1668 11 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Clinical Application of Detecting 21-Gene Recurrence Score in Predicating Prognosis and Therapy Response of Patients with Breast Cancer from Two Medical Centers

Xiao, G., Meng, J., Zhang, J., Li, G., Du, N., Qin, S., Wang, J., Xu, C., Ren, H., Tang, S-C. & Sun, X., Nov 26 2017, In : Cancer Investigation. 35, 10, p. 639-646 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Clonal evolution and outcomes in myelofibrosis after ruxolitinib discontinuation

Newberry, K. J., Patel, K., Masarova, L., Luthra, R., Manshouri, T., Jabbour, E., Bose, P., Daver, N., Cortes, J., Kantarjian, H. & Verstovsek, S., Aug 31 2017, In : Blood. 130, 9, p. 1125-1131 7 p.

Research output: Contribution to journalArticle

Open Access
50 Scopus citations

Clostridium difficile infection in dialysis patients

Tirath, A., Tadros, S., Coffin, S. L., Kintziger, K. W., Waller, J. L., Baer, S., Colombo, R. E., Huber, L. Y., Kheda, M. F. & Nahman, N. S., Feb 2017, In : Journal of Investigative Medicine. 65, 2, p. 353-357 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Combined inhibition of β-catenin and Bcr–Abl synergistically targets tyrosine kinase inhibitor-resistant blast crisis chronic myeloid leukemia blasts and progenitors in vitro and in vivo

Zhou, H., Mak, P. Y., Mu, H., Mak, D. H., Zeng, Z., Cortes, J., Liu, Q., Andreeff, M. & Carter, B. Z., Apr 18 2017, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

37 Scopus citations

Concurrent PD-1 blockade negates the effects of OX40 agonist antibody in combination immunotherapy through inducing T-cell apoptosis

Shrimali, R. K., Ahmad, S., Verma, V., Zeng, P., Ananth, S., Gaur, P., Gittelman, R. M., Yusko, E., Sanders, C., Robins, H., Hammond, S. A., Janik, J. E., Mkrtichyan, M., Gupta, S. & Khleif, S. N., Sep 2017, In : Cancer Immunology Research. 5, 9, p. 755-766 12 p.

Research output: Contribution to journalArticle

62 Scopus citations
18 Scopus citations

Corrigendum to “KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study” [Leuk. Res. 50 (Nov) (2016) 123–131. PubMed PMID: 27736729](S0145212616301989)(10.1016/j.leukres.2016.09.012)

Swords, R. T., Greenberg, P. L., Wei, A. H., Durrant, S., Advani, A. S., Hertzberg, M. S., Lewis, I. D., Rivera, G., Gratzinger, D., Fan, A. C., Felsher, D. W., Cortes, J. E., Watts, J. M., Yarranton, G. T., Walling, J. M. & Lancet, J. E., Aug 2017, In : Leukemia Research. 59, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Crizanlizumab for the prevention of pain crises in sickle cell disease

Ataga, K. I., Kutlar, A., Kanter, J., Liles, D., Cancado, R., Friedrisch, J., Guthrie, T. H., Knight-Madden, J., Alvarez, O. A., Gordeuk, V. R., Gualandro, S., Colella, M. P., Smith, W. R., Rollins, S. A., Stocker, J. W. & Rother, R. P., Feb 2 2017, In : New England Journal of Medicine. 376, 5, p. 429-439 11 p.

Research output: Contribution to journalArticle

164 Scopus citations

Crizanlizumab in sickle cell disease

Ataga, K. I., Kutlar, A. & Kanter, J., May 4 2017, In : New England Journal of Medicine. 376, 18, p. 1795-1796 2 p.

Research output: Contribution to journalLetter

18 Scopus citations

CrossTalk proposal: Skeletal muscle oxidative capacity is altered in patients with cystic fibrosis

Rodriguez-Miguelez, P., Erickson, M. L., McCully, K. K. & Harris, R. A., Mar 1 2017, In : Journal of Physiology. 595, 5, p. 1423-1425 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Deficiency of LRP1 in Mature Adipocytes Promotes Diet-Induced Inflammation and Atherosclerosis-Brief Report

Konaniah, E. S., Kuhel, D. G., Basford, J. E., Weintraub, N. L. & Hui, D. Y., Jun 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 6, p. 1046-1049 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Designing therapeutic cancer vaccines by mimicking viral infections

Sultan, H., Fesenkova, V. I., Addis, D., Fan, A. E., Kumai, T., Wu, J., Salazar, A. M. & Celis, E., Feb 1 2017, In : Cancer Immunology, Immunotherapy. 66, 2, p. 203-213 11 p.

Research output: Contribution to journalReview article

15 Scopus citations

Differential PI3Kδ signaling in CD4+ T-cell subsets enables selective targeting of t regulatory cells to enhance cancer immunotherapy

Ahmad, S., Abu-Eid, R., Shrimali, R. K., Webb, M., Verma, V., Doroodchi, A., Berrong, Z., Samara, R., Rodriguez, P. C., Mkrtichyan, M. & Khleif, S. N., Apr 15 2017, In : Cancer Research. 77, 8, p. 1892-1904 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Does the frequency of molecular monitoring after tyrosine kinase inhibitor discontinuation affect outcomes of patients with chronic myeloid leukemia?

Kong, J. H., Winton, E. F., Heffner, L. T., Chen, Z., Langston, A. A., Hill, B., Arellano, M., El-Rassi, F., Kim, A., Jillella, A., Kota, V., Bodó, I. & Khoury, H. J., Jul 1 2017, In : Cancer. 123, 13, p. 2482-2488 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Does the risk of diabetes and heart disease in women with polycystic ovary syndrome lessen with age?

Azziz, R., Dec 1 2017, In : Fertility and sterility. 108, 6, p. 959-960 2 p.

Research output: Contribution to journalEditorial

3 Scopus citations

Dual-energy X-ray absorptiometry and fracture prediction in patients with spinal cord injuries and disorders

Abderhalden, L., Weaver, F. M., Bethel, M., Demirtas, H., Burns, S., Svircev, J., Hoenig, H., Lyles, K., Miskevics, S. & Carbone, L. D., Mar 1 2017, In : Osteoporosis International. 28, 3, p. 925-934 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Early transcatheter valve prosthesis degeneration and future ramifications

Arora, S., Ramm, C. J., Misenheimer, J. A. & Vavalle, J. P., Jan 1 2017, In : Cardiovascular Diagnosis and Therapy. 7, 1, p. 1-3 3 p.

Research output: Contribution to journalReview article

7 Scopus citations

Effective antitumor peptide vaccines can induce severe autoimmune pathology

Sultan, H., Trillo-Tinoco, J., Rodriguez, P. & Celis, E., Jan 1 2017, In : Oncotarget. 8, 41, p. 70317-70331 15 p.

Research output: Contribution to journalArticle

6 Scopus citations