Obstetrics and Gynecology

Research Output 1966 2019

2017
3 Citations (Scopus)

Oxidative stress: a key regulator of leiomyoma cell survival

Fletcher, N. M., Abusamaan, M. S., Memaj, I., Saed, M. G., Al-Hendy, A., Diamond, M. P. & Saed, G. M., Jun 1 2017, In : Fertility and sterility. 107, 6, p. 1387-1394.e1

Research output: Contribution to journalArticle

Leiomyoma
Cell Survival
Oxidative Stress
Nitric Oxide Synthase Type II
Peroxidase
4 Citations (Scopus)

PCOS: Animal models for PCOS-not the real thing

Azziz, R., Jul 1 2017, In : Nature Reviews Endocrinology. 13, 7, p. 382-384 3 p.

Research output: Contribution to journalComment/debate

Animal Models
2 Citations (Scopus)

Peri-muscular adipose tissue may play a unique role in determining insulin sensitivity/resistance in women with polycystic ovary syndrome

Morrison, S. A., Goss, A. M., Azziz, R., Raju, D. A. & Gower, B. A., Jan 1 2017, In : Human Reproduction. 32, 1, p. 185-192 8 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Insulin Resistance
Adipose Tissue
Thigh
Homeostasis
8 Citations (Scopus)

Perspectives on polycystic ovary syndrome: Is polycystic ovary syndrome research underfunded?

Brakta, S., Lizneva, D., Mykhalchenko, K., Imam, A., Walker, W., Diamond, M. P. & Azziz, R., Jan 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 12, p. 4421-4427 7 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
National Institutes of Health (U.S.)
Health
Systemic Lupus Erythematosus
Rheumatoid Arthritis
6 Citations (Scopus)

Polycystic Ovarian Syndrome: Long-Term Health Consequences

Zore, T., Joshi, N. V., Lizneva, D. & Azziz, R., May 1 2017, In : Seminars in Reproductive Medicine. 35, 3, p. 271-281 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Health
Morbidity
Psychological Sexual Dysfunctions
Glucose Intolerance
16 Citations (Scopus)

Psychological manifestations of celiac disease autoimmunity in young children

The TEDDY study group, Mar 1 2017, In : Pediatrics. 139, 3, e20162848.

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Psychology
Mothers
Autoantibodies

Recurrent low grade serous ovarian cancer in a 20 year old woman: A case from the Ohio State University College of Medicine

Cohn, DE., Backes, FJ., Wallbillich, J. J., Bixel, K., Crafton, SM., Neff, R., ElNaggar, AC., Smith, B. & Suarez, AA., Mar 2017, In : Gynecologic Oncology. p. 451-455 5 p., 28161140.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

On behalf of the TEDDY Study Group, Oct 1 2017, In : Diabetologia. 60, 10, p. 1931-1940 10 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Respiratory Tract Infections
Autoantibodies
Tracheitis
4 Citations (Scopus)

RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins

Chen, F., Wang, Y., Rafikov, R., Haigh, S., Kumar, S., Rafikova, O., Lucas, R., Verin, A. D., Black, S. M. & Fulton, D. J., Mar 1 2017, In : Biochemical Pharmacology. 127, p. 34-45 12 p.

Research output: Contribution to journalArticle

Bacterial Toxins
Nitric Oxide
glutathione-independent formaldehyde dehydrogenase
Lung
Calcium

Role of Markov Modeling Approaches to Understand the Impact of Infertility Treatments

Rao, A. S. R. & Diamond, M. P., Nov 1 2017, In : Reproductive Sciences. 24, 11, p. 1538-1543 6 p.

Research output: Contribution to journalArticle

Infertility
Therapeutics
Mobile Applications
Clomiphene
Aromatase Inhibitors
3 Citations (Scopus)

Role of Stro1+/CD44+ stem cells in myometrial physiology and uterine remodeling during pregnancy

Mas, A., Prusinski, L., Yang, Q., Diaz-Gimeno, P., Stone, L., Diamond, M. P., Simón, C. & Al-Hendy, A., Jan 1 2017, In : Biology of reproduction. 96, 1, p. 70-80 11 p., 143461.

Research output: Contribution to journalArticle

Stem Cells
Pregnancy
Uterus
Cell Proliferation
Parity
14 Citations (Scopus)

ROS signaling in the pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS)

Kellner, M., Noonepalle, S., Lu, Q., Srivastava, A., Zemskov, E. A. & Black, S. M., Jan 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 105-137 33 p. (Advances in Experimental Medicine and Biology; vol. 967).

Research output: Chapter in Book/Report/Conference proceedingChapter

Acute Lung Injury
Adult Respiratory Distress Syndrome
Reactive Oxygen Species
Permeability
Oxidative stress
5 Citations (Scopus)

Salud es Vida: a Cervical Cancer Screening Intervention for Rural Latina Immigrant Women

Luque, J. S., Tarasenko, Y. N., Reyes-Garcia, C., Alfonso, M. L., Suazo, N., Rebing, L. & Ferris, D. G., Dec 1 2017, In : Journal of Cancer Education. 32, 4, p. 690-699 10 p.

Research output: Contribution to journalArticle

Papanicolaou Test
Early Detection of Cancer
Hispanic Americans
Uterine Cervical Neoplasms
Self Efficacy
12 Citations (Scopus)

Selective progesterone receptor modulators for fertility preservation in women with symptomatic uterine fibroids

Ali, M. & Al-Hendy, A., Jan 1 2017, In : Biology of reproduction. 97, 3, p. 337-352 16 p.

Research output: Contribution to journalReview article

Fertility Preservation
Leiomyoma
Progesterone Receptors
Fertility
Therapeutics
5 Citations (Scopus)

Serum complexed and free prostate-specific antigen (PSA) for the diagnosis of the polycystic ovarian syndrome (PCOS)

Diamandis, E. P., Stanczyk, F. Z., Wheeler, S., Mathew, A., Stengelin, M., Nikolenko, G., Glezer, E. N., Brown, M. D., Zheng, Y., Chen, Y-H., Wu, H. L. & Azziz, R., Oct 26 2017, In : Clinical Chemistry and Laboratory Medicine. 55, 11, p. 1789-1797 9 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Prostate-Specific Antigen
Biomarkers
Serum
Hyperandrogenism
6 Citations (Scopus)

Sexual function in infertile women with polycystic ovary syndrome and unexplained infertility

Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network, Aug 1 2017, In : American journal of obstetrics and gynecology. 217, 2, p. 191.e1-191.e19

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Infertility
Androgens
Equipment and Supplies
Testosterone
31 Citations (Scopus)

The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history on the progression from multiple autoantibodies to type 1 diabetes: A teddy study report

Krischer, J. P., Liu, X., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G. & Akolkar, B., Dec 1 2017, In : Diabetes. 66, 12, p. 3122-3129 8 p.

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Type 1 Diabetes Mellitus
Autoantibodies
HLA-DQ Antigens
HLA-DR Antigens
84 Citations (Scopus)

Treatment of endometriosis-associated pain with elagolix, an oral GnRH antagonist

Taylor, H. S., Giudice, L. C., Lessey, B. A., Abrao, M. S., Kotarski, J., Archer, D. F., Diamond, M. P., Surrey, E., Johnson, N. P., Watts, N. B., Gallagher, J. C., Simon, J. A., Carr, B., Dmowski, W. P., Leyland, N., Rowan, J. P., Duan, W. R., Ng, J., Schwefel, B., Thomas, J. W. & 2 others, Jain, R. I. & Chwalisz, K., Jul 6 2017, In : New England Journal of Medicine. 377, 1, p. 28-40 13 p.

Research output: Contribution to journalArticle

Hormone Antagonists
Endometriosis
Gonadotropin-Releasing Hormone
Pain
Dysmenorrhea
26 Citations (Scopus)

Updates of the role of oxidative stress in the pathogenesis of ovarian cancer

Saed, G. M., Diamond, M. P. & Fletcher, N. M., Jun 1 2017, In : Gynecologic Oncology. 145, 3, p. 595-602 8 p.

Research output: Contribution to journalReview article

Ovarian Neoplasms
Oxidative Stress
Reactive Nitrogen Species
Neoplasms
Reactive Oxygen Species
2 Citations (Scopus)

Uterine Fibroids: Bridging Genomic Defects and Chronic Inflammation

El Andaloussi, A., Chaudhry, Z., Al-Hendy, A. & Ismail, N., Nov 1 2017, In : Seminars in Reproductive Medicine. 35, 6, p. 494-498 5 p.

Research output: Contribution to journalArticle

Leiomyoma
Inflammation
Mutation
Myoma
Pelvic Pain
13 Citations (Scopus)

Uterine Fibroids: Burden and Unmet Medical Need

Al-Hendy, A., Myers, E. R. & Stewart, E., Nov 1 2017, In : Seminars in Reproductive Medicine. 35, 6, p. 473-480 8 p.

Research output: Contribution to journalArticle

Leiomyoma
Fertility
Population
Therapeutics
Costs and Cost Analysis
2 Citations (Scopus)

Uterine Leiomyoma: New Perspectives on an Old Disease

Segars, J. H. & Al-Hendy, A., Nov 1 2017, In : Seminars in Reproductive Medicine. 35, 6, p. 471-472 2 p.

Research output: Contribution to journalEditorial

Leiomyoma
5 Citations (Scopus)

What is the role of retroperitoneal exploration in optimally debulked stage IIIC epithelial ovarian cancer? An NRG Oncology/Gynecologic Oncology Group ancillary data study

Rungruang, B. J., Miller, A., Krivak, T. C., Horowitz, N. S., Rodriguez, N., Hamilton, C. A., Backes, F. J., Carson, L. F., Friedlander, M., Mutch, D. G., Goodheart, M. J., Tewari, K. S., Wenham, R. M., Bookman, M. A., Maxwell, G. L. & Richard, S. D., Mar 15 2017, In : Cancer. 123, 6, p. 985-993 9 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Survival
Lymph Nodes
Neoplasms
Ovarian epithelial cancer
9 Citations (Scopus)

Zebrafish knockout of Down syndrome gene, DYRK1A, shows social impairments relevant to autism

Kim, O. H., Cho, H. J., Han, E., Hong, T. I., Ariyasiri, K., Choi, J. H., Hwang, K. S., Jeong, Y. M., Yang, S. Y., Yu, K., Park, D. S., Oh, H. W., Davis, E. E., Schwartz, C. E., Lee, J. S., Kim, H. G. & Kim, C. H., Sep 29 2017, In : Molecular Autism. 8, 1, 168.

Research output: Contribution to journalArticle

Zebrafish
Autistic Disorder
Down Syndrome
Microcephaly
Genes
2016
1 Citation (Scopus)

35 yaş üzeri in-vitro fertilizasyon over follikül sıvı proteomların çözümlenmesi

Translated title of the contribution: Decoding the proteome of In-Vitro fertilization ovarian follicular fluid for women over 35 yearsMohamed, S., Hassanin, I. M. A., Ait-Allah, A. S., Mohamed, S. M., Helmy, Y. A. & Al-Hendy, A., Jan 1 2016, In : Journal of Clinical and Analytical Medicine. 7, 1, p. 60-64 5 p.

Research output: Contribution to journalArticle

Follicular Fluid
Fertilization in Vitro
Proteome
Proteins
Pregnancy Outcome
4 Citations (Scopus)

A balanced chromosomal translocation involving chromosomes 3 and 16 in a patient with Mayer-Rokitansky-Kuster-Hauser syndrome reveals new candidate genes at 3p22.3 and 16p13.3

Williams, L. S., Kim, H. G., Kalscheuer, V. M., Tuck, J. M., Chorich, L. P., Sullivan, M. E., Falkenstrom, A., Reindollar, R. H. & Layman, L. C., Jul 30 2016, In : Molecular Cytogenetics. 9, 1, 57.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 16
Genetic Translocation
Chromosomes, Human, Pair 3
Chromosomes
Genes
6 Citations (Scopus)
Regression Analysis
Pediatrics
Logistic Models
Population
Health
14 Citations (Scopus)

Activation of calpain-2 by mediators in pulmonary vascular remodeling of pulmonary arterial hypertension

Kovacs, L., Han, W., Rafikov, R., Bagi, Z., Offermanns, S., Saido, T. C., Black, S. M. & Su, Y., Mar 1 2016, In : American journal of respiratory cell and molecular biology. 54, 3, p. 384-393 10 p.

Research output: Contribution to journalArticle

Calpain
Pulmonary Hypertension
Chemical activation
Lung
Muscle
5 Citations (Scopus)

Adhesion phenotype manifests an altered metabolic profile favoring glycolysis

Fletcher, N. M., Awonuga, A. O., Abusamaan, M. S., Saed, M. G., Diamond, M. P. & Saed, G. M., Jun 1 2016, In : Fertility and Sterility. 105, 6, p. 1628-1637.e1

Research output: Contribution to journalArticle

Metabolome
Glycolysis
Fibroblasts
Phenotype
Hypoxia-Inducible Factor 1
2 Citations (Scopus)

Adipose-derived human stem/stromal cells: comparative organ specific mitochondrial bioenergy profiles

Ferng, A. S., Marsh, K. M., Fleming, J. M., Conway, R. F., Schipper, D., Bajaj, N., Connell, A. M., Pilikian, T., Johnson, K., Runyan, R., Black, S. M., Szivek, J. A. & Khalpey, Z., Dec 1 2016, In : SpringerPlus. 5, 1, 2057.

Research output: Contribution to journalArticle

Stromal Cells
Stem Cells
Energy Metabolism
Adipose Tissue
Respiration
5 Citations (Scopus)
Laparoscopy
Multicenter Studies
Hydrogel
Uterine Myomectomy
Tissue Adhesions
12 Citations (Scopus)

Altered Biomarkers in Trophoblast Cells Obtained Noninvasively Prior to Clinical Manifestation of Perinatal Disease

Bolnick, J. M., Kohan-Ghadr, H. R., Fritz, R., Bolnick, A. D., Kilburn, B. A., Diamond, M. P., Armant, D. R. & Drewlo, S., Sep 23 2016, In : Scientific Reports. 6, 32382.

Research output: Contribution to journalArticle

Trophoblasts
Biomarkers
Pre-Eclampsia
Cervix Uteri
Pregnancy
4 Citations (Scopus)

Altered expression of histone deacetylases, inflammatory cytokines and contractile-associated factors in uterine myometrium of Long Evans rats gestationally exposed to benzo[a]pyrene

Laknaur, A., Foster, T. L., Bobb, L. E., Ramesh, A., Ladson, G. M., Hood, D. B., Al-Hendy, A. & Thota, C., Jun 1 2016, In : Journal of Applied Toxicology. 36, 6, p. 827-835 9 p.

Research output: Contribution to journalArticle

Long Evans Rats
Histone Deacetylases
Myometrium
Benzo(a)pyrene
Premature Birth
6 Citations (Scopus)

A microdeletion at Xq22.2 implicates a glycine receptor GLRA4 involved in intellectual disability, behavioral problems and craniofacial anomalies

Labonne, J. D. J., Graves, T. D., Shen, Y., Jones, J. R., Kong, I. K., Layman, L. C. & Kim, H. G., Aug 9 2016, In : BMC Neurology. 16, 1, 132.

Research output: Contribution to journalArticle

Glycine Receptors
Intellectual Disability
Genes
Pelizaeus-Merzbacher Disease
X-Linked Genes
13 Citations (Scopus)

An atypical 12q24.31 microdeletion implicates six genes including a histone demethylase KDM2B and a histone methyltransferase SETD1B in syndromic intellectual disability

Labonne, J. D. J., Lee, K. H., Iwase, S., Kong, I. K., Diamond, M. P., Layman, L. C., Kim, C. H. & Kim, H. G., Jul 1 2016, In : Human Genetics. 135, 7, p. 757-771 15 p.

Research output: Contribution to journalArticle

Histone Demethylases
Intellectual Disability
Genes
Untranslated RNA
Zebrafish
19 Citations (Scopus)

Androgen excess: Investigations and management

Lizneva, D., Gavrilova-Jordan, L. P., Walker, W. & Azziz, R., Nov 1 2016, In : Best Practice and Research: Clinical Obstetrics and Gynaecology. 37, p. 98-118 21 p.

Research output: Contribution to journalReview article

Androgens
Alopecia
Hirsutism
Acne Vulgaris
Hyperandrogenism
12 Citations (Scopus)

An Open Letter to the Food and Drug Administration Regarding the Use of Morcellation Procedures in Women Having Surgery for Presumed Uterine Myomas

Parker, W., Berek, J. S., Pritts, E., Olive, D., Kaunitz, A. M., Chalas, E., Clarke-Pearson, D., Goff, B., Bristow, R., Taylor, H. S., Farias-Eisner, R., Fader, A. N., Maxwell, G. L., Goodwin, S. C., Love, S., Gibbons, W. E., Foshag, L. J., Leppert, P. C., Norsigian, J., Nager, C. W. & 26 others, Johnson, T., Guzick, D. S., As-Sanie, S., Paulson, R. J., Farquhar, C., Bradley, L., Scheib, S. A., Bilchik, A. J., Rice, L. W., Dionne, C., Jacoby, A., Ascher-Walsh, C., Kilpatrick, S. J., Adamson, G. D., Siedhoff, M., Israel, R., Paraiso, M. F., Frumovitz, M. M., Lurain, J. R., Al-Hendy, A., Benrubi, G. I., Raman, S. S., Kho, R. M., Anderson, T. L., Reynolds, R. K. & DeLancey, J., Mar 1 2016, In : Journal of Minimally Invasive Gynecology. 23, 3, p. 303-308 6 p.

Research output: Contribution to journalEditorial

A note from the editor-in-chief

Devoe, L. D., Dec 1 2016, In : Journal of Reproductive Medicine. 61, 6, p. 527-528 2 p.

Research output: Contribution to journalEditorial

A note from the editor-in-chief

Devoe, L. D., Feb 1 2016, In : Journal of Reproductive Medicine. 61, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

A note from the editor-in-chief

Devoe, L. D., Apr 1 2016, In : Journal of Reproductive Medicine. 61, 2, p. 93-94 2 p.

Research output: Contribution to journalArticle

A note from the editor-in-chief

Devoe, L. D., Aug 1 2016, In : Journal of Reproductive Medicine. 61, 4, p. 309-310 2 p.

Research output: Contribution to journalEditorial

A note from the editor-in-chief

Devoe, L. D., Oct 1 2016, In : Journal of Reproductive Medicine. 61, 5, p. 403-404 2 p.

Research output: Contribution to journalEditorial

8 Citations (Scopus)

A personalized paradigm in the treatment of platinum-resistant ovarian cancer: A cost utility analysis of genomic-based versus cytotoxic therapy

Wallbillich, J. J., Forde, B., Havrilesky, LJ. & Cohn, DE., Jul 2016, In : Gynecologic Oncology. 142, 1, p. 144-149 6 p., 27106017.

Research output: Contribution to journalArticle

22 Citations (Scopus)
Assisted Reproductive Techniques
Intracytoplasmic Sperm Injections
Methylation
DNA Methylation
Fertilization in Vitro
85 Citations (Scopus)

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study

Dietary Biomarkers Laboratory, Project Scientist, Other contributors, Autoantibody Reference Laboratories, Cortisol Laboratory, Data Coordinating Center, Pennsylvania Satellite Center, Washington Clinical Center, Sweden Clinical Center, Finland Clinical Center, Germany Clinical Center, Georgia/Florida Clinical Center, for the TEDDY Study Group, SNP Laboratory, RNA Laboratory and Gene Expression Laboratory, Microbiome and Viral Metagenomics Laboratory, Metabolomics Laboratory, HbA1c Laboratory, HLA Reference Laboratory, OGTT Laboratory & 2 others, Proteomics Laboratory & Repository, Jan 2016, In : JAMA Pediatrics. 170, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

Probiotics
Autoimmunity
Type 1 Diabetes Mellitus
Genotype
Autoantibodies
4 Citations (Scopus)

Association study of androgen signaling pathway genes in polycystic ovary syndrome

Ketefian, A., Jones, M. R., Krauss, R. M., Chen, Y. D. I., Legro, R. S., Azziz, R. & Goodarzi, M. O., Feb 1 2016, In : Fertility and sterility. 105, 2, p. 467-473.e4

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Androgens
Genes
Single Nucleotide Polymorphism
Androgen Receptors
1 Citation (Scopus)

Asymmetric dimethylarginine stimulates Akt1 phosphorylation via heat shock protein 70-facilitated carboxyl-terminal modulator protein degradation in pulmonary arterial endothelial cells

Sun, X., Kellner, M., Desai, A. A., Wang, T., Lu, Q., Kangath, A., Qu, N., Klinger, C., Fratz, S., Yuan, J. X. J., Jacobson, J. R., Garcia, J. G. N., Rafikov, R., Fineman, J. R. & Black, S. M., Aug 1 2016, In : American journal of respiratory cell and molecular biology. 55, 2, p. 275-287 13 p.

Research output: Contribution to journalArticle

Phosphorylation
HSP70 Heat-Shock Proteins
Endothelial cells
Modulators
Proteolysis
31 Citations (Scopus)

ATP promotes cell survival via regulation of cytosolic [Ca2+] and Bcl-2/Bax ratio in lung cancer cells

Song, S., Jacobson, K. N., McDermott, K. M., Reddy, S. P., Cress, A. E., Tang, H., Dudek, S. M., Black, S. M., Garcia, J. G. N., Makino, A. & Yuan, J. X. J., Jan 15 2016, In : American Journal of Physiology - Cell Physiology. 310, 2, p. C99-C114

Research output: Contribution to journalArticle

Lung Neoplasms
Cell Survival
Adenosine Triphosphate
bcl-2-Associated X Protein
Tumor Microenvironment

Atypical presentations of molar pregnancy: Diagnostic roles of imaging, ß-human chorionic gonadotropin measurement, and p57 immunostaining

Mohamed, S. A., Al-Hendy, A., Ghamande, S. A., Chaffin, J. & Browne, P. C., Mar 1 2016, In : Journal of Ultrasound in Medicine. 35, 3, p. 643-649 7 p.

Research output: Contribution to journalArticle

Gestational Trophoblastic Disease
Hydatidiform Mole
Chorionic Gonadotropin
Diagnostic Imaging
Cyclin-Dependent Kinase Inhibitor p57
5 Citations (Scopus)

Baseline AMH level associated with ovulation following ovulation induction in women with Polycystic Ovary Syndrome

Mumford, S. L., Legro, R. S., Diamond, M. P., Coutifaris, C., Steiner, A. Z., Schlaff, W. D., Alvero, R., Christman, G. M., Casson, P. R., Huang, H., Santoro, N., Eisenberg, E., Zhang, H. & Cedars, M. I., Sep 1 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3288-3296 9 p.

Research output: Contribution to journalArticle

Aromatase
Ovulation Induction
Polycystic Ovary Syndrome
Ovulation
Progesterone