Research Output

Filter
Article
2020

Adenosine kinase inhibition enhances microvascular dilator function and improves left ventricle diastolic dysfunction

Davila, A., Tian, Y., Czikora, I., S. Weissman, A., Weinand, N., Dong, G., Xu, J., Li, J., Su, H., Kapuku, G., Huo, Y. & Bagi, Z., Jan 1 2020, (Accepted/In press) In : Microcirculation.

Research output: Contribution to journalArticle

Age-related increase of kynurenine enhances miR29b-1-5p to decrease both CXCL12 signaling and the epigenetic enzyme Hdac3 in bone marrow stromal cells

Elmansi, A. M., Hussein, K. A., Herrero, S. M., Periyasamy-Thandavan, S., Aguilar-Pérez, A., Kondrikova, G., Kondrikov, D., Eisa, N. H., Pierce, J. L., Kaiser, H., Ding, K. H., Walker, A. L., Jiang, X., Bollag, W. B., Elsalanty, M., Zhong, Q., Shi, X. M., Su, Y., Johnson, M., Hunter, M. & 7 others, Reitman, C., Volkman, B. F., Hamrick, M. W., Isales, C. M., Fulzele, S., McGee-Lawrence, M. E. & Hill, W. D., Jun 2020, In : Bone Reports. 12, 100270.

Research output: Contribution to journalArticle

Open Access
Open Access
1 Scopus citations

An unexpected dependence of cortical depth in shaping neural responsiveness and selectivity in mouse visual cortex

O’herron, P., Levy, M., Woodward, J. J. & Kara, P., Jan 1 2020, In : eNeuro. 7, 2, ENEURO.0497-19.2020.

Research output: Contribution to journalArticle

Open Access
Open Access

Blockade of Toll-like receptor 4 (TLR4) reduces oxidative stress and restores phospho-ERK1/2 levels in Leydig cells exposed to high glucose

Karpova, T., de Oliveira, A. A., Naas, H., Priviero, F. & Nunes, K. P., Mar 15 2020, In : Life sciences. 245, 117365.

Research output: Contribution to journalArticle

CCL2 mediates early renal leukocyte infiltration during salt-sensitive hypertension

Alsheikh, A. J., Dasinger, J. H., Abais-Battad, J. M., Fehrenbach, D. J., Yang, C., Cowley, A. W. & Mattson, D. L., Apr 1 2020, In : American journal of physiology. Renal physiology. 318, 4, p. F982-F993

Research output: Contribution to journalArticle

Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization

Jackson, L., Dong, G., Althomali, W., Sayed, M. A., Eldahshan, W., Baban, B., Johnson, M. H., Filosa, J., Fagan, S. C. & Ergul, A., Aug 1 2020, In : Translational Stroke Research. 11, 4, p. 762-775 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

Dioleoylphosphatidylglycerol accelerates corneal epithelial wound healing

Bollag, W. B., Olala, L. O., Xie, D., Lu, X., Qin, H., Choudhary, V., Patel, R., Bogorad, D., Estes, A. & Watsky, M., Mar 2020, In : Investigative Ophthalmology and Visual Science. 61, 3, 29.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Double-stranded RNA and Toll-like receptor activation: A novel mechanism for blood pressure regulation

Dela Justina, V., Giachini, F. R., Priviero, F. & Webb, R. C., Jan 1 2020, In : Clinical Science. 134, 2, p. 303-313 11 p.

Research output: Contribution to journalArticle

Electrolyte and transporter responses to angiotensin II induced hypertension in female and male rats and mice

Veiras, L. C., McFarlin, B. E., Ralph, D. L., Buncha, V., Prescott, J., Shirvani, B. S., McDonough, J. C., Ha, D., Giani, J., Gurley, S. B., Mamenko, M. & McDonough, A. A., May 1 2020, In : Acta Physiologica. 229, 1, e13448.

Research output: Contribution to journalArticle

Epigenetic Modifications in T Cells: The Role of DNA Methylation in Salt-Sensitive Hypertension

Dasinger, J. H., Alsheikh, A. J., Abais-Battad, J. M., Pan, X., Fehrenbach, D. J., Lund, H., Roberts, M. L., Cowley, A. W., Kidambi, S., Kotchen, T. A., Liu, P., Liang, M. & Mattson, D. L., Feb 1 2020, In : Hypertension. p. 372-382 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Greater T Regulatory Cells in Females Attenuate DOCA-Salt-Induced Increases in Blood Pressure Versus Males

Belanger, K. M., Crislip, G. R., Gillis, E. E., Abdelbary, M., Musall, J. B., Mohamed, R., Baban, B., Elmarakby, A., Brands, M. W. & Sullivan, J. C., 2020, (Accepted/In press) In : Hypertension. p. 1615-1623 9 p.

Research output: Contribution to journalArticle

In vivo two-photon imaging of neuronal and brain vascular responses in mice chronically exposed to ethanol

O'Herron, P., Summers, P. M., Shih, A. Y., Kara, P. & Woodward, J. J., Jun 2020, In : Alcohol. 85, p. 41-47 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo

Pierce, J. L., Roberts, R. L., Yu, K., Kendall, R. K., Kaiser, H., Davis, C., Johnson, M. H., Hill, W. D., Isales, C. M., Bollag, W. B., Hamrick, M. W. & McGee-Lawrence, M. E., Feb 2020, In : Experimental Gerontology. 130, 110818.

Research output: Contribution to journalArticle

1 Scopus citations

NOX2-derived reactive oxygen species in immune cells exacerbates salt-sensitive hypertension

Abais-Battad, J. M., Lund, H., Dasinger, J. H., Fehrenbach, D. J., Cowley, A. W. & Mattson, D. L., Jan 2020, In : Free Radical Biology and Medicine. 146, p. 333-339 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

O-GlcNAc impairs endothelial function in uterine arteries from virgin but not pregnant rats: The role of GSK3β

Dela Justina, V., Priviero, F., dos Passos, R. R., Webb, R. C., Lima, V. V. & Giachini, F. R., Aug 5 2020, In : European Journal of Pharmacology. 880, 173133.

Research output: Contribution to journalArticle

1 Scopus citations

Picolinic acid, a tryptophan oxidation product, does not impact bone mineral density but increases marrow adiposity

Ding, K., McGee-Lawrence, M. E., Kaiser, H., Sharma, A. K., Pierce, J. L., Irsik, D. L., Bollag, W. B., Xu, J., Zhong, Q., Hill, W. D., Shi, X. M., Fulzele, S., Kennedy, E. J., Elsalanty, M. E., Hamrick, M. W. & Isales, C. M., May 2020, In : Experimental Gerontology. 133, 110885.

Research output: Contribution to journalArticle

1 Scopus citations

Splenocyte transfer exacerbates salt-sensitive hypertension in rats

Fehrenbach, D. J., Dasinger, J. H., Lund, H., Zemaj, J. & Mattson, D. L., Jan 1 2020, (Accepted/In press) In : Experimental Physiology.

Research output: Contribution to journalArticle

1 Scopus citations

The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress

Lee, H., Smith, S. B., Sheu, S. S. & Yoon, Y., May 8 2020, In : Journal of Biological Chemistry. 295, 19, p. 6543-6560 18 p.

Research output: Contribution to journalArticle

Open Access

Toll-like receptor 9 regulates metabolic profile and contributes to obesity-induced benign prostatic hyperplasia in mice

Calmasini, F. B., McCarthy, C. G., Wenceslau, C. F., Priviero, F. B. M., Antunes, E. & Webb, R. C., Feb 1 2020, In : Pharmacological Reports. 72, 1, p. 179-187 9 p.

Research output: Contribution to journalArticle

Twenty-four-hour versus clinic blood pressure levels as predictors of long-term cardiovascular and renal disease outcomes among African Americans

Kidambi, S., Wang, T., Chelius, T., Nunuk, I., Agarwal, P., Laud, P., Mattson, D., Cowley, A. W., Liang, M. & Kotchen, T., Dec 1 2020, In : Scientific reports. 10, 1, 11685.

Research output: Contribution to journalArticle

Open Access
2019
4 Scopus citations

Angiotensin receptor (AT2R) agonist C21 prevents cognitive decline after permanent stroke in aged animals—A randomized double- blind pre-clinical study

Ahmed, H. A., Ishrat, T., Pillai, B., Bunting, K. M., Vazdarjanova, A., Waller, J. L., Ergul, A. & Fagan, S. C., Feb 1 2019, In : Behavioural Brain Research. 359, p. 560-569 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Association of leptin gene polymorphism with economic traits in crossbred cattle

Choudhary, V., Kumar, P., Mishra, C., Bhattacharya, T. K., Bhushan, B. & Sharma, A., Jan 1 2019, In : Indian Journal of Animal Sciences. 89, 9, p. 974-978 5 p.

Research output: Contribution to journalArticle

Augmented astrocyte microdomain Ca 2+ dynamics and parenchymal arteriole tone in angiotensin II-infused hypertensive mice

Diaz, J. R., Kim, K. J., Brands, M. W. & Filosa, J. A., Mar 2019, In : Glia. 67, 3, p. 551-565 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Bif-1 interacts with prohibitin-2 to regulate mitochondrial inner membrane during cell stress and apoptosis

Cho, S. G., Xiao, X., Wang, S., Gao, H., Rafikov, R., Black, S., Huang, S., Ding, H. F., Yoon, Y., Kirken, R. A., Yin, X. M., Wang, H. G. & Dong, Z., Jul 2019, In : Journal of the American Society of Nephrology. 30, 7, p. 1174-1191 18 p.

Research output: Contribution to journalArticle

5 Scopus citations
3 Scopus citations

Diabetic Stroke Promotes a Sexually Dimorphic Expansion of T Cells

Jackson, L., Li, W., Abdul, Y., Dong, G., Baban, B. & Ergul, A., Dec 1 2019, In : NeuroMolecular Medicine. 21, 4, p. 445-453 9 p.

Research output: Contribution to journalArticle

Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome

Abais-Battad, J. M., Alsheikh, A. J., Pan, X., Fehrenbach, D. J., Dasinger, J. H., Lund, H., Roberts, M. L., Kriegel, A. J., Cowley, A. W., Kidambi, S., Kotchen, T. A., Liu, P., Liang, M. & Mattson, D. L., Oct 1 2019, In : Hypertension. 74, 4, p. 854-863 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dose–response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke

Ishrat, T., Fouda, A. Y., Pillai, B., Eldahshan, W., Ahmed, H., Waller, J. L., Ergul, A. & Fagan, S. C., Aug 1 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 8, p. 1635-1647 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Endothelial adenosine kinase deficiency ameliorates diet-induced insulin resistance

Xu, J., Yang, Q., Zhang, X., Liu, Z., Cao, Y., Wang, L., Zhou, Y., Zeng, X., Ma, Q., Xu, Y., Wang, Y., Huang, L., Han, Z., Wang, T., Stepp, D., Bagi, Z., Wu, C., Hong, M. & Huo, Y., Aug 1 2019, In : The Journal of endocrinology. 242, 2, p. 159-172 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Enhancer of zeste homolog 2 (EZH2) regulates adipocyte lipid metabolism independent of adipogenic differentiation: Role of apolipoprotein e

Yiew, N. K. H., Greenway, C., Zarzour, A., Ahmadieh, S., Goo, B., Kim, D., Benson, T. W., Ogbi, M., Tang, Y. L., Chen, W., Stepp, D., Patel, V., Hilton, R., Lu, X. Y., Hui, D. Y., Kim, H. W. & Weintraub, N. L., May 24 2019, In : Journal of Biological Chemistry. 294, 21, p. 8577-8591 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Equilin displays similar endothelium-independent vasodilator potential to 17β-estradiol regardless of lower potential to inhibit calcium entry

Filgueira, F. P., Lobato, N. S., Nascimento, D. L., Ceravolo, G. S., Giachini, F. R. C., Lima, V. V., Dantas, A. P., Fortes, Z. B., Webb, R. C., Tostes, R. C. & Carvalho, M. H. C., Jan 2019, In : Steroids. 141, p. 46-54 9 p.

Research output: Contribution to journalArticle

Excess homocysteine upregulates the NRF2-antioxidant pathway in retinal Müller glial cells

Navneet, S., Cui, X., Zhao, J., Wang, J., Kaidery, N. A., Thomas, B., Bollinger, K. E., Yoon, Y. & Smith, S. B., Jan 2019, In : Experimental eye research. 178, p. 228-237 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels

Bagi, Z., Couch, Y., Broskova, Z., Perez-Balderas, F., Yeo, T., Davis, S., Fischer, R., Sibson, N. R., Davis, B. G. & Anthony, D. C., Dec 1 2019, In : Scientific reports. 9, 1, 15847.

Research output: Contribution to journalArticle

Open Access

Formyl peptide receptor-1 activation exerts a critical role for the dynamic plasticity of arteries via actin polymerization

Wenceslau, C. F., McCarthy, C. G., Szasz, T., Calmasini, F. B., Mamenko, M. & Webb, R. C., Mar 2019, In : Pharmacological Research. 141, p. 276-290 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Galectin-3 is expressed in vascular smooth muscle cells and promotes pulmonary hypertension through changes in proliferation, apoptosis, and fibrosis

Barman, S. A., Li, X., Haigh, S., Kondrikov, D., Mahboubi, K., Bordan, Z., Stepp, D. W., Zhou, J., Wang, Y., Weintraub, D. S., Traber, P., Snider, W., Jonigk, D., Sullivan, J., Ryan Crislip, G., Butcher, J. T., Thompson, J., Su, Y., Chen, F. & Fulton, D. J. R., May 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 316, 5, p. L784-L797

Research output: Contribution to journalArticle

6 Scopus citations

Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension

Rafikov, R., Nair, V., Sinari, S., Babu, H., Sullivan, J. C., Yuan, J. X. J., Desai, A. A. & Rafikova, O., Nov 1 2019, In : Antioxidants and Redox Signaling. 31, 13, p. 917-932 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

Hirsutanol A attenuates lipopolysaccharide-mediated matrix metalloproteinase 9 expression and cytokines production and improves endotoxemia-induced acute sickness behavior and acute lung injury

Jan, J. S., Yang, C. H., Wang, M. H., Lin, F. L., Yen, J. L., Hsieh, I., Khotimchenko, M., Lee, T. H. & Hsiao, G., Jun 17 2019, In : Marine Drugs. 17, 6, 360.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2

Navneet, S., Zhao, J., Wang, J., Mysona, B. A., Barwick, S., Ammal Kaidery, N., Saul, A. B., Kaddour-Djebbar, I., Bollag, W. B., Thomas, B., Bollinger, K. E. & Smith, S. B., Jun 2019, In : Redox Biology. 24, 101199.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Increased ENaC activity during kidney preservation in Wisconsin solution

Khedr, S., Palygin, O., Pavlov, T. S., Blass, G., Levchenko, V., Alsheikh, A., Brands, M. W., El-Meanawy, A. & Staruschenko, A., Apr 29 2019, In : BMC Nephrology. 20, 1, 145.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4

Abdul, Y., Abdelsaid, M., Li, W., Webb, R. C., Sullivan, J. C., Dong, G. & Ergul, A., Mar 1 2019, In : Molecular Neurobiology. 56, 3, p. 1607-1617 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Interleukin-10 negatively modulates extracellular signal-regulated kinases 1 and 2 in aorta from hypertensive mouse induced by angiotensin II infusion

Bressan, A. F., Fonseca, G. A., Tostes, R. C., Webb, R. C., Lima, V. V. & Giachini, F. R., Feb 1 2019, In : Fundamental and Clinical Pharmacology. 33, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2 Scopus citations

Leptin restores endothelial function via endothelial PPARγ-nox1-mediated mechanisms in a mouse model of congenital generalized lipodystrophy

Bruder-Nascimento, T., Faulkner, J. L., Haigh, S., Kennard, S., Antonova, G., Patel, V. S., Fulton, D. J. R., Chen, W. & De Chantemèle, E. J. B., Dec 1 2019, In : Hypertension. 74, 6, p. 1399-1408 10 p.

Research output: Contribution to journalArticle