• 1816 Citations
  • 25 h-Index
20032019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2003 2019

  • 1816 Citations
  • 25 h-Index
  • 44 Article
  • 5 Review article
  • 1 Chapter
  • 1 Comment/debate
2019

Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain

Elmarakby, A. A., Faulkner, J., Pati, P., Dan Rudic, R. & Bergson, C. M., Feb 1 2019, In : PloS one. 14, 2, e0211903.

Research output: Contribution to journalArticle

Open Access
Attention Deficit Disorder with Hyperactivity
Prosencephalon
Arterial Pressure
Genes
brain
2 Citations (Scopus)

Tetrahydrobiopterin improves endothelial function in patients with cystic fibrosis

Jeong, J. H., Lee, N., Tucker, M. A., Rodriguez-Miguelez, P., Looney, J., Thomas, J., Derella, C. C., Elmarakby, A. A., Musall, J. B., Sullivan, J. C., McKie, K. T., Forseen, C. J., Davison, G. W. & Harris, R. A., Jan 1 2019, In : Journal of Applied Physiology. 126, 1, p. 60-66 7 p.

Research output: Contribution to journalArticle

Cystic Fibrosis
Dilatation
Blood Vessels
Nitric Oxide
Biological Availability
2018
2 Citations (Scopus)
Celecoxib
Albuminuria
Cyclooxygenase 2 Inhibitors
Blood pressure
Inbred SHR Rats
2017
1 Citation (Scopus)
meloxicam
Epoxide Hydrolases
Streptozocin
Rats
Acids
2016
6 Citations (Scopus)
Inbred SHR Rats
Angiotensin II
Hemodynamics
Glomerular Filtration Rate
Arterial Pressure
8 Citations (Scopus)

Novel molecular triggers underlie valproate-induced liver injury and its alleviation by the omega-3 fatty acid DHA: role of inflammation and apoptosis

El-Mowafy, A. M., Katary, M. M., Pye, C., Ibrahim, A. S. & Elmarakby, A. A., Jul 1 2016, In : Heliyon. 2, 7, e00130.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Valproic Acid
Apoptosis
Inflammation
Liver
2015
38 Citations (Scopus)

Curcumin attenuates iron accumulation and oxidative stress in the liver and spleen of chronic iron-overloaded rats

Badria, F. A., Ibrahim, A. S., Badria, A. F. & Elmarakby, A. A., Jul 31 2015, In : PLoS One. 10, 7, e0134156.

Research output: Contribution to journalArticle

Curcumin
Oxidative stress
curcumin
Liver
iron overload
2014
15 Citations (Scopus)

Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms

Pye, C., Elsherbiny, N. M., Ibrahim, A. S., Liou, G. I., Chadli, A., Al-Shabrawey, M. & Elmarakby, A. A., Jan 1 2014, In : Pharmacological Research. 85, p. 45-54 10 p.

Research output: Contribution to journalArticle

Adenosine Kinase
Experimental Diabetes Mellitus
Oxidants
Anti-Inflammatory Agents
Kidney
21 Citations (Scopus)

Valproate-induced liver injury: Modulation by the omega-3 fatty acid DHA proposes a novel anticonvulsant regimen

Abdel-Dayem, M. A., Elmarakby, A. A., Abdel-Aziz, A. A., Pye, C., Said, S. A. & El-Mowafy, A. M., Jan 1 2014, In : Drugs in R and D. 14, 2, p. 85-94 10 p.

Research output: Contribution to journalArticle

Docosahexaenoic Acids
Omega-3 Fatty Acids
Valproic Acid
Anticonvulsants
Liver
2013
45 Citations (Scopus)

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase

Othman, A., Ahmad, S., Megyerdi, S., Mussell, R., Choksi, K., Maddipati, K. R., Elmarakby, A. A., Rizk, N. & Al-Shabrawey, M., Feb 20 2013, In : PloS one. 8, 2, e57254.

Research output: Contribution to journalArticle

NADPH Oxidase
Endothelial cells
Metabolites
lipoxygenase
endothelial cells

Erratum: Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: Implications in retinal neovascularization (Diabetes (2011) 60 (614-624))

Al-Shabrawey, M., Mussell, R., Kahook, K., Tawfik, A. M., Eladl, M., Sarthy, V., Nussbaum, J. J., Elmarakby, A. A., Park, S. Y., Gurel, Z., Sheibani, N. & Maddipati, K. R., Mar 1 2013, In : Diabetes. 62, 3, 1 p.

Research output: Contribution to journalComment/debate

Arachidonate 12-Lipoxygenase
Retinal Neovascularization
Diabetic Retinopathy
Oxygen
15 Citations (Scopus)
Inbred SHR Rats
NG-Nitroarginine Methyl Ester
Nitric Oxide Synthase
Blood Pressure
T-Lymphocytes
39 Citations (Scopus)

Renal collecting duct nos1 maintains fluid-electrolyte homeostasis and blood pressure

Hyndman, K. A., Boesen, E. I., Elmarakby, A. A., Brands, M. W., Huang, P., Kohan, D. E., Pollock, D. M. & Pollock, J. S., Jul 1 2013, In : Hypertension. 62, 1, p. 91-98 8 p.

Research output: Contribution to journalArticle

Electrolytes
Homeostasis
Water-Electrolyte Balance
Nitrites
Blood Pressure
19 Citations (Scopus)

Role of haem oxygenase in the renoprotective effects of soluble epoxide hydrolase inhibition in diabetic spontaneously hypertensive rats

Elmarakby, A. A., Faulkner, J., Pye, C., Rouch, K., Alhashim, A., Maddipati, K. R. & Baban, B., Oct 1 2013, In : Clinical Science. 125, 7, p. 349-359 11 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Heme Oxygenase (Decyclizing)
Inbred SHR Rats
Kidney
Fibrosis
2012
36 Citations (Scopus)
Heme Oxygenase-1
Inbred SHR Rats
Apoptosis
Wounds and Injuries
Oxidative Stress
16 Citations (Scopus)
Heme Oxygenase-1
Inbred SHR Rats
Oxidative Stress
Inflammation
Kidney
28 Citations (Scopus)

Intrafibrillar silicification of collagen scaffolds for sustained release of stem cell homing chemokine in hard tissue regeneration

Niu, L. N., Jiao, K., Qi, Y. P., Nikonov, S., Yiu, C. K. Y., Arola, D. D., Gong, S. Q., Elmarakby, A. A., Carrilho, M. R. O., Hamrick, M. W., Hargreaves, K. M., Diogenes, A., Chen, J. H., Pashley, D. H. & Tay, F. C. M., Nov 1 2012, In : FASEB Journal. 26, 11, p. 4517-4529 13 p.

Research output: Contribution to journalArticle

Tissue regeneration
Stem cells
Chemokines
Scaffolds
Regeneration
26 Citations (Scopus)
Inbred SHR Rats
Sex Characteristics
Angiotensin II
Oxidative Stress
Hypertension
13 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Angiotensin II
Interleukin-6
Hypertension
Fenofibrate
253 Citations (Scopus)

Relationship between oxidative stress and inflammatory cytokines in diabetic nephropathy

Elmarakby, A. A. & Sullivan, J. C., Feb 1 2012, In : Cardiovascular Therapeutics. 30, 1, p. 49-59 11 p.

Research output: Contribution to journalReview article

Diabetic Nephropathies
Oxidative Stress
Cytokines
Inflammation
Type 1 Diabetes Mellitus
29 Citations (Scopus)
Cardiovascular Diseases
Epoxide Hydrolases
Acids
Chronic Kidney Failure
Animal Models
2011
56 Citations (Scopus)
Epoxide Hydrolases
Streptozocin
Type 1 Diabetes Mellitus
Inflammation
Kidney
56 Citations (Scopus)

Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: Implications in retinal neovascularization

Al-Shabrawey, M., Mussell, R., Kahook, K., Tawfik, A. M., Eladl, M., Sarthy, V., Nussbaum, J. J., Elmarakby, A. A., Park, S. Y., Gurel, Z., Sheibani, N. & Maddipati, K. R., Feb 1 2011, In : Diabetes. 60, 2, p. 614-624 11 p.

Research output: Contribution to journalArticle

Arachidonate 12-Lipoxygenase
Retinal Neovascularization
Hydroxyeicosatetraenoic Acids
Diabetic Retinopathy
Oxygen
20 Citations (Scopus)
NADPH Oxidase
Oxidative Stress
Pressure
Superoxide Dismutase
Uric Acid
17 Citations (Scopus)
Desoxycorticosterone Acetate
Fenofibrate
Peroxisome Proliferator-Activated Receptors
Cyclooxygenase 2
Cytochrome P-450 Enzyme System
8 Citations (Scopus)

Submandibular gland and caries susceptibility in the obese Zucker rat

Mozaffari, M. S., Abdelsayed, R. A., Zakhary, I., Elsalanty, M. E., Liu, J. Y., Wimborne, H. & Elmarakby, A. A., Feb 1 2011, In : Journal of Oral Pathology and Medicine. 40, 2, p. 194-200 7 p.

Research output: Contribution to journalArticle

Zucker Rats
Submandibular Gland
Insulin Resistance
Obesity
NF-kappa B
39 Citations (Scopus)

Tyrosine kinase inhibitor, genistein, reduces renal inflammation and injury in streptozotocin-induced diabetic mice

Elmarakby, A. A., Ibrahim, A. S., Faulkner, J., Mozaffari, M. S., Liou, G. I. & Abdelsayed, R. A., Nov 1 2011, In : Vascular Pharmacology. 55, 5-6, p. 149-156 8 p.

Research output: Contribution to journalArticle

Genistein
Streptozocin
Protein-Tyrosine Kinases
Inflammation
Kidney
2010
69 Citations (Scopus)

Angiotensin (1-7) receptor antagonism equalizes angiotensin II-induced hypertension in male and female spontaneously hypertensive rats

Sullivan, J. C., Bhatia, K., Yamamoto, T. & Elmarakby, A. A., Oct 1 2010, In : Hypertension. 56, 4, p. 658-666 9 p.

Research output: Contribution to journalArticle

Inbred SHR Rats
Angiotensin II
Hypertension
7-Ala-angiotensin (1-7)
Blood Pressure
34 Citations (Scopus)

Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions

Imig, J. D., Elmarakby, A. A., Nithipatikom, K., Wei, S., Capdevila, J. H., Tuniki, V. R., Sangras, B., Anjaiah, S., Manthati, V. L., Reddy, D. S. & Falck, J. R., Dec 1 2010, In : Frontiers in Physiology. 1 DEC, Artilce 157.

Research output: Contribution to journalArticle

Antihypertensive Agents
Ether
Blood Pressure
Inbred SHR Rats
Acids
17 Citations (Scopus)

Induction of hemeoxygenase-1 attenuates the hypertension and renal inflammation in spontaneously hypertensive rats

Elmarakby, A. A., Faulkner, J., Posey, S. P. & Sullivan, J. C., Nov 1 2010, In : Pharmacological Research. 62, 5, p. 400-407 8 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Renal Hypertension
Inbred SHR Rats
Inflammation
Proteinuria
22 Citations (Scopus)

Inflammatory cytokines as predictive markers for early detection and progression of diabetic nephropathy

Elmarakby, A. A., Abdelsayed, R. A., Liu, J. Y. & Mozaffari, M. S., Mar 1 2010, In : EPMA Journal. 1, 1, p. 117-129 13 p.

Research output: Contribution to journalReview article

Diabetic Nephropathies
Cytokines
Chemokines
Chronic Kidney Failure
Biomarkers
47 Citations (Scopus)

Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats

Elmarakby, A. A. & Imig, J. D., Jan 1 2010, In : Clinical Science. 118, 4, p. 291-301 11 p.

Research output: Contribution to journalArticle

High Fat Diet
Blood Vessels
Obesity
Inflammation
Hypertension
2009
19 Citations (Scopus)

Effects of chromium picolinate on glycemic control and kidney of the obese zucker rat

Mozaffari, M. S., Abdelsayed, R. A., Liu, J. Y., Wimborne, H., El-Remessy, A. & Elmarakby, A. A., Dec 1 2009, In : Nutrition and Metabolism. 6, 51.

Research output: Contribution to journalArticle

Zucker Rats
Kidney
Chromium
DNA Damage
Oxidative Stress
21 Citations (Scopus)

Obesity induced renal oxidative stress contributes to renal injury in salt-sensitive hypertension

Quigley, J. E., Elmarakby, A. A., Knight, S. F., Manhiani, M. M., Stepp, D. W., Olearzcyk, J. J. & Imig, J. D., Jul 1 2009, In : Clinical and Experimental Pharmacology and Physiology. 36, 7, p. 724-728 5 p.

Research output: Contribution to journalArticle

Desoxycorticosterone
Oxidative Stress
Obesity
Salts
Hypertension
55 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Peroxisomes
NADPH Oxidase
Oxygen
Blood Vessels
2008
83 Citations (Scopus)

Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet

Knight, S. F., Quigley, J. E., Yuan, J., Roy, S. S., Elmarakby, A. A. & Imig, J. D., Feb 1 2008, In : Hypertension. 51, 2, p. 352-359 8 p.

Research output: Contribution to journalArticle

High Fat Diet
Inbred SHR Rats
Fats
Kidney
Wounds and Injuries
42 Citations (Scopus)

SPARC ameliorates ovarian cancer-associated inflammation

Said, N. A., Elmarakby, A. A., Imig, J. D., Fulton, D. J. & Motamed, K., Jan 1 2008, In : Neoplasia. 10, 10, p. 1092-1104 13 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Cysteine
Inflammation
Macrophages
Proteins
94 Citations (Scopus)

TNF-α inhibition reduces renal injury in DOCA-salt hypertensive rats

Elmarakby, A. A., Quigley, J. E., Imig, J. D., Pollock, J. S. & Pollock, D. M., Jan 1 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 1

Research output: Contribution to journalArticle

Desoxycorticosterone Acetate
Salts
Kidney
Wounds and Injuries
Chemokine CCL2
2007
41 Citations (Scopus)

Chemokine receptor 2b inhibition provides renal protection in angiotensin II-salt hypertension

Elmarakby, A. A., Quigley, J. E., Olearczyk, J. J., Sridhar, A., Cook, A. K., Inscho, E. W., Pollock, D. M. & Imig, J. D., Dec 1 2007, In : Hypertension. 50, 6, p. 1069-1076 8 p.

Research output: Contribution to journalArticle

Chemokine Receptors
Angiotensin II
Salts
Hypertension
Kidney
63 Citations (Scopus)

Normalization of the ovarian cancer microenvironment by SPARC

Said, N., Socha, M. J., Olearczyk, J. J., Elmarakby, A. A., Imig, J. D. & Motamed, K., Oct 1 2007, In : Molecular Cancer Research. 5, 10, p. 1015-1030 16 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Ovarian Neoplasms
Vascular Endothelial Growth Factor A
Cysteine
Ascites
13 Citations (Scopus)

Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension

Elmarakby, A. A., Williams, J. M., Imig, J. D., Pollock, J. S. & Pollock, D. M., Feb 1 2007, In : Vascular Pharmacology. 46, 2, p. 144-151 8 p.

Research output: Contribution to journalArticle

Enalapril
Angiotensin II
Hypertension
8-epi-prostaglandin F2alpha
Blood Pressure
2006

Renal dysfunction in hypertension and obesity

Elmarakby, A. A., Pollock, D. M. & Imig, J. D., Nov 1 2006, Comprehensive Medicinal Chemistry II. Elsevier Ltd., Vol. 6. p. 575-595 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

86 Citations (Scopus)

Tumor necrosis factor α blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension

Elmarakby, A. A., Quigley, J. E., Pollock, D. M. & Imig, J. D., Mar 1 2006, In : Hypertension. 47, 3 II, p. 557-562 6 p.

Research output: Contribution to journalArticle

Angiotensins
Tumor Necrosis Factor-alpha
Salts
Hypertension
Kidney
2005
106 Citations (Scopus)

Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats

D'Angelo, G., Elmarakby, A. A., Pollock, D. M. & Stepp, D. W., Oct 1 2005, In : Hypertension. 46, 4, p. 806-811 6 p.

Research output: Contribution to journalArticle

Fructose
Sprague Dawley Rats
Insulin Resistance
Blood Pressure
Plethysmography
93 Citations (Scopus)

NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1

Elmarakby, A. A., Loomis, E. D., Pollock, J. S. & Pollock, D. M., Feb 1 2005, In : Hypertension. 45, 2, p. 283-287 5 p.

Research output: Contribution to journalArticle

NADPH Oxidase
8-epi-prostaglandin F2alpha
Oxidative Stress
Hypertension
Superoxides
2004
36 Citations (Scopus)

ETA receptor blockade attenuates hypertension and decreases reactive oxygen species in ETB receptor-deficient rats

Elmarakby, A. A., Loomis, E. D., Pollock, J. S. & Pollock, D. M., Nov 1 2004, In : Journal of Cardiovascular Pharmacology. 44, SUPPL. 1

Research output: Contribution to journalArticle

Reactive Oxygen Species
Hypertension
Blood Pressure
Endothelin A Receptors
Salts
26 Citations (Scopus)

Reduced NOS3 Phosphorylation Mediates Reduced NO/cGMP Signaling in Mesenteric Arteries of Deoxycorticosterone Acetate-Salt Hypertensive Rats

Sasser, J. M., Sullivan, J. C., Elmarakby, A. A., Kemp, B. E., Pollock, D. M. & Pollock, J. S., May 1 2004, In : Hypertension. 43, 5, p. 1080-1085 6 p.

Research output: Contribution to journalArticle

Desoxycorticosterone
Mesenteric Arteries
Acetates
Salts
Phosphorylation
2003
9 Citations (Scopus)

Enalapril attenuates endothelin-1-induced hypertension via increased kinin survival

Elmarakby, A. A., Morsing, P. & Pollock, D. M., Jun 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 6 53-6

Research output: Contribution to journalArticle

Kinins
Enalapril
Endothelin-1
Hypertension
Arterial Pressure
13 Citations (Scopus)

Estradiol relaxes rat aorta via endothelium-dependent and -independent mechanisms

Abou-Mohamed, G., Elmarakby, A. A., Carrier, G. O., Catravas, J. D., Caldwell, R. W. & White, R. E., Aug 11 2003, In : Pharmacology. 69, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

Endothelium
Aorta
Estradiol
Estrogens
Nitroarginine
10 Citations (Scopus)

Omapatrilat increases renal endothelin in deoxycorticosterone acetate-salt hypertensive rats

Elmarakby, A. A., Morsing, P., Pollock, J. S. & Pollock, D. M., Dec 1 2003, In : Vascular Pharmacology. 40, 5, p. 253-259 7 p.

Research output: Contribution to journalArticle

Desoxycorticosterone
Endothelins
Neprilysin
Acetates
Enalapril