• 2067 Citations
  • 26 h-Index
20032020

Research output per year

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Research Output

  • 2067 Citations
  • 26 h-Index
  • 47 Article
  • 5 Review article
  • 1 Chapter
  • 1 Comment/debate
Article

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase

Othman, A., Ahmad, S., Megyerdi, S., Mussell, R., Choksi, K., Maddipati, K. R., Elmarakby, A., Rizk, N. & Al-Shabrawey, M., Feb 20 2013, In : PloS one. 8, 2, e57254.

Research output: Contribution to journalArticle

55 Scopus citations

Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms

Pye, C., Elsherbiny, N. M., Ibrahim, A. S., Liou, G. I., Chadli, A., Al-Shabrawey, M. & Elmarakby, A. A., Jul 2014, In : Pharmacological Research. 85, p. 45-54 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

A dual role of 12/15-lipoxygenase in LPS-induced acute renal inflammation and injury

Elmarakby, A. A., Ibrahim, A. S., Katary, M. A., Elsherbiny, N. M., El-Shafey, M., Abd-Elrazik, A. M., Abdelsayed, R. A., Maddipati, K. R. & Al-Shabrawey, M., Nov 2019, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 11, p. 1669-1680 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Angiotensin (1-7) receptor antagonism equalizes angiotensin II-induced hypertension in male and female spontaneously hypertensive rats

Sullivan, J. C., Bhatia, K., Yamamoto, T. & Elmarakby, A. A., Oct 2010, In : Hypertension. 56, 4, p. 658-666 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

Chemokine receptor 2b inhibition provides renal protection in angiotensin II-salt hypertension

Elmarakby, A. A., Quigley, J. E., Olearczyk, J. J., Sridhar, A., Cook, A. K., Inscho, E. W., Pollock, D. M. & Imig, J. D., Dec 2007, In : Hypertension. 50, 6, p. 1069-1076 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Curcumin attenuates iron accumulation and oxidative stress in the liver and spleen of chronic iron-overloaded rats

Badria, F. A., Ibrahim, A. S., Badria, A. F. & Elmarakby, A. A., Jul 31 2015, In : PloS one. 10, 7, e0134156.

Research output: Contribution to journalArticle

51 Scopus citations
60 Scopus citations

Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions

Imig, J. D., Elmarakby, A., Nithipatikom, K., Wei, S., Capdevila, J. H., Tuniki, V. R., Sangras, B., Anjaiah, S., Manthati, V. L., Reddy, D. S. & Falck, J. R., 2010, In : Frontiers in Physiology. 1 DEC, Artilce 157.

Research output: Contribution to journalArticle

36 Scopus citations

Effects of chromium picolinate on glycemic control and kidney of the obese zucker rat

Mozaffari, M. S., Abdelsayed, R., Liu, J. Y., Wimborne, H., El-Remessy, A. & El-Marakby, A., 2009, In : Nutrition and Metabolism. 6, 51.

Research output: Contribution to journalArticle

20 Scopus citations

Enalapril attenuates endothelin-1-induced hypertension via increased kinin survival

Elmarakby, A. A., Morsing, P. & Pollock, D. M., Jun 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 6 53-6, p. H1899-H1903

Research output: Contribution to journalArticle

9 Scopus citations

Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet

Knight, S. F., Quigley, J. E., Yuan, J., Roy, S. S., Elmarakby, A. & Imig, J. D., Feb 2008, In : Hypertension. 51, 2, p. 352-359 8 p.

Research output: Contribution to journalArticle

87 Scopus citations

Estradiol relaxes rat aorta via endothelium-dependent and -independent mechanisms

Abou-Mohamed, G., Elmarakby, A., Carrier, G. O., Catravas, J. D., Caldwell, R. W. & White, R. E., Aug 11 2003, In : Pharmacology. 69, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

ETA receptor blockade attenuates hypertension and decreases reactive oxygen species in ETB receptor-deficient rats

Elmarakby, A. A., Loomis, E. D., Pollock, J. S. & Pollock, D. M., Nov 2004, In : Journal of Cardiovascular Pharmacology. 44, SUPPL. 1, p. S7-S10

Research output: Contribution to journalArticle

36 Scopus citations
22 Scopus citations

Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats

D'Angelo, G., Elmarakby, A. A., Pollock, D. M. & Stepp, D. W., Oct 2005, In : Hypertension. 46, 4, p. 806-811 6 p.

Research output: Contribution to journalArticle

105 Scopus citations

Greater T Regulatory Cells in Females Attenuate DOCA-Salt-Induced Increases in Blood Pressure Versus Males

Belanger, K. M., Crislip, G. R., Gillis, E. E., Abdelbary, M., Musall, J. B., Mohamed, R., Baban, B., Elmarakby, A., Brands, M. W. & Sullivan, J. C., 2020, (Accepted/In press) In : Hypertension. p. 1615-1623 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
7 Scopus citations

Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain

Elmarakby, A., Faulkner, J., Pati, P., Dan Rudic, R. & Bergson, C., Feb 2019, In : PloS one. 14, 2, e0211903.

Research output: Contribution to journalArticle

Open Access

Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: Implications in retinal neovascularization

Al-Shabrawey, M., Mussell, R., Kahook, K., Tawfik, A., Eladl, M., Sarthy, V., Nussbaum, J., El-Marakby, A., Park, S. Y., Gurel, Z., Sheibani, N. & Maddipati, K. R., Feb 2011, In : Diabetes. 60, 2, p. 614-624 11 p.

Research output: Contribution to journalArticle

63 Scopus citations

Induction of hemeoxygenase-1 attenuates the hypertension and renal inflammation in spontaneously hypertensive rats

Elmarakby, A. A., Faulkner, J., Posey, S. P. & Sullivan, J. C., Nov 1 2010, In : Pharmacological Research. 62, 5, p. 400-407 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
39 Scopus citations
19 Scopus citations
5 Scopus citations

Intrafibrillar silicification of collagen scaffolds for sustained release of stem cell homing chemokine in hard tissue regeneration

Niu, L. N., Jiao, K., Qi, Y. P., Nikonov, S., Yiu, C. K. Y., Arola, D. D., Gong, S. Q., El-Marakby, A., Carrilho, M. R. O., Hamrick, M. W., Hargreaves, K. M., Diogenes, A., Chen, J. H., Pashley, D. H. & Tay, F. R., Nov 2012, In : FASEB Journal. 26, 11, p. 4517-4529 13 p.

Research output: Contribution to journalArticle

33 Scopus citations
21 Scopus citations

NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1

Elmarakby, A. A., Loomis, E. D., Pollock, J. S. & Pollock, D. M., Feb 2005, In : Hypertension. 45, 2, p. 283-287 5 p.

Research output: Contribution to journalArticle

98 Scopus citations

Normalization of the ovarian cancer microenvironment by SPARC

Said, N., Socha, M. J., Olearczyk, J. J., Elmarakby, A. A., Imig, J. D. & Motamed, K., Oct 1 2007, In : Molecular Cancer Research. 5, 10, p. 1015-1030 16 p.

Research output: Contribution to journalArticle

68 Scopus citations

Novel molecular triggers underlie valproate-induced liver injury and its alleviation by the omega-3 fatty acid DHA: role of inflammation and apoptosis

El-Mowafy, A. M., Katary, M. M., Pye, C., Ibrahim, A. S. & Elmarakby, A. A., Jul 1 2016, In : Heliyon. 2, 7, e00130.

Research output: Contribution to journalArticle

10 Scopus citations

Obesity induced renal oxidative stress contributes to renal injury in salt-sensitive hypertension

Quigley, J. E., Elmarakby, A. A., Knight, S. F., Manhiani, M. M., Stepp, D. W., Olearzcyk, J. J. & Imig, J. D., Jul 2009, In : Clinical and Experimental Pharmacology and Physiology. 36, 7, p. 724-728 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats

Elmarakby, A. A. & Imig, J. D., 2010, In : Clinical Science. 118, 4, p. 291-301 11 p.

Research output: Contribution to journalArticle

57 Scopus citations

Omapatrilat increases renal endothelin in deoxycorticosterone acetate-salt hypertensive rats

Elmarakby, A. A., Morsing, P., Pollock, J. S. & Pollock, D. M., Dec 1 2003, In : Vascular Pharmacology. 40, 5, p. 253-259 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
38 Scopus citations
15 Scopus citations
19 Scopus citations

Reduced NOS3 Phosphorylation Mediates Reduced NO/cGMP Signaling in Mesenteric Arteries of Deoxycorticosterone Acetate-Salt Hypertensive Rats

Sasser, J. M., Sullivan, J. C., Elmarakby, A. A., Kemp, B. E., Pollock, D. M. & Pollock, J. S., May 2004, In : Hypertension. 43, 5, p. 1080-1085 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Renal collecting duct nos1 maintains fluid-electrolyte homeostasis and blood pressure

Hyndman, K. A., Boesen, E. I., Elmarakby, A. A., Brands, M. W., Huang, P., Kohan, D. E., Pollock, D. M. & Pollock, J. S., Jul 2013, In : Hypertension. 62, 1, p. 91-98 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Role of haem oxygenase in the renoprotective effects of soluble epoxide hydrolase inhibition in diabetic spontaneously hypertensive rats

Elmarakby, A. A., Faulkner, J., Pye, C., Rouch, K., Alhashim, A., Maddipati, K. R. & Baban, B., Oct 1 2013, In : Clinical Science. 125, 7, p. 349-359 11 p.

Research output: Contribution to journalArticle

21 Scopus citations
Open Access
4 Scopus citations

SPARC ameliorates ovarian cancer-associated inflammation

Said, N. A., Elmarakby, A. A., Imig, J. D., Fulton, D. J. & Motamed, K., Oct 2008, In : Neoplasia. 10, 10, p. 1092-1104 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

Submandibular gland and caries susceptibility in the obese Zucker rat

Mozaffari, M. S., Abdelsayed, R., Zakhary, I., El-Salanty, M., Liu, J. Y., Wimborne, H. & El-Marakby, A., Feb 2011, In : Journal of Oral Pathology and Medicine. 40, 2, p. 194-200 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
65 Scopus citations

Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension

Elmarakby, A. A., Williams, J. M., Imig, J. D., Pollock, J. S. & Pollock, D. M., Feb 2007, In : Vascular Pharmacology. 46, 2, p. 144-151 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Tetrahydrobiopterin improves endothelial function in patients with cystic fibrosis

Jeong, J. H., Lee, N., Tucker, M. A., Rodriguez-Miguelez, P., Looney, J., Thomas, J., Derella, C. C., Elmarakby, A. A., Musall, J. B., Sullivan, J. C., McKie, K. T., Forseen, C. J., Davison, G. W. & Harris, R. A., Jan 2019, In : Journal of Applied Physiology. 126, 1, p. 60-66 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

TNF-α inhibition reduces renal injury in DOCA-salt hypertensive rats

Elmarakby, A. A., Quigley, J. E., Imig, J. D., Pollock, J. S. & Pollock, D. M., Jan 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 1, p. R76-R83

Research output: Contribution to journalArticle

101 Scopus citations

Tumor necrosis factor α blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension

Elmarakby, A. A., Quigley, J. E., Pollock, D. M. & Imig, J. D., Mar 2006, In : Hypertension. 47, 3 II, p. 557-562 6 p.

Research output: Contribution to journalArticle

90 Scopus citations

Tyrosine kinase inhibitor, genistein, reduces renal inflammation and injury in streptozotocin-induced diabetic mice

Elmarakby, A. A., Ibrahim, A. S., Faulkner, J., Mozaffari, M. S., Liou, G. I. & Abdelsayed, R., Nov 1 2011, In : Vascular Pharmacology. 55, 5-6, p. 149-156 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Valproate-induced liver injury: Modulation by the omega-3 fatty acid DHA proposes a novel anticonvulsant regimen

Abdel-Dayem, M. A., Elmarakby, A. A., Abdel-Aziz, A. A., Pye, C., Said, S. A. & El-Mowafy, A. M., Jun 2014, In : Drugs in R and D. 14, 2, p. 85-94 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
Chapter

Renal dysfunction in hypertension and obesity

Elmarakby, A. A., Pollock, D. M. & Imig, J. D., Nov 1 2006, Comprehensive Medicinal Chemistry II. Elsevier Ltd., Vol. 6. p. 575-595 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
Comment/debate

Erratum: Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: Implications in retinal neovascularization (Diabetes (2011) 60 (614-624))

Al-Shabrawey, M., Mussell, R., Kahook, K., Tawfik, A., Eladl, M., Sarthy, V., Nussbaum, J., El-Marakby, A., Park, S. Y., Gurel, Z., Sheibani, N. & Maddipati, K. R., Mar 2013, In : Diabetes. 62, 3, p. 998 1 p.

Research output: Contribution to journalComment/debate

Review article

Inflammatory cytokines as predictive markers for early detection and progression of diabetic nephropathy

Elmarakby, A. A., Abdelsayed, R., Liu, J. Y. & Mozaffari, M. S., Mar 2010, In : EPMA Journal. 1, 1, p. 117-129 13 p.

Research output: Contribution to journalReview article

24 Scopus citations